Amino acid dipepetide frequency for [Clostridium] hylemonae DSM 15053

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.5AlaAla: 9.5 ± 0.134	1.287AlaCys: 1.287 ± 0.036	5.101AlaAsp: 5.101 ± 0.066	5.865AlaGlu: 5.865 ± 0.072	3.177AlaPhe: 3.177 ± 0.059	8.027AlaGly: 8.027 ± 0.101	1.217AlaHis: 1.217 ± 0.033	4.163AlaIle: 4.163 ± 0.061	4.182AlaLys: 4.182 ± 0.064	7.331AlaLeu: 7.331 ± 0.097	2.371AlaMet: 2.371 ± 0.045	2.263AlaAsn: 2.263 ± 0.048	2.219AlaPro: 2.219 ± 0.053	2.274AlaGln: 2.274 ± 0.044	3.639AlaArg: 3.639 ± 0.065	4.143AlaSer: 4.143 ± 0.063	2.826AlaThr: 2.826 ± 0.055	7.841AlaVal: 7.841 ± 0.098	0.584AlaTrp: 0.584 ± 0.022	2.857AlaTyr: 2.857 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.194CysAla: 1.194 ± 0.032	0.3CysCys: 0.3 ± 0.016	0.814CysAsp: 0.814 ± 0.025	0.913CysGlu: 0.913 ± 0.026	0.655CysPhe: 0.655 ± 0.021	1.695CysGly: 1.695 ± 0.041	0.325CysHis: 0.325 ± 0.017	1.215CysIle: 1.215 ± 0.035	0.703CysLys: 0.703 ± 0.027	1.284CysLeu: 1.284 ± 0.032	0.512CysMet: 0.512 ± 0.021	0.523CysAsn: 0.523 ± 0.021	0.674CysPro: 0.674 ± 0.026	0.35CysGln: 0.35 ± 0.017	1.02CysArg: 1.02 ± 0.03	0.939CysSer: 0.939 ± 0.025	0.856CysThr: 0.856 ± 0.026	1.089CysVal: 1.089 ± 0.029	0.128CysTrp: 0.128 ± 0.01	0.568CysTyr: 0.568 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	4.411AspAla: 4.411 ± 0.068	0.829AspCys: 0.829 ± 0.028	2.833AspAsp: 2.833 ± 0.07	4.454AspGlu: 4.454 ± 0.065	2.256AspPhe: 2.256 ± 0.051	4.606AspGly: 4.606 ± 0.077	0.845AspHis: 0.845 ± 0.024	4.81AspIle: 4.81 ± 0.071	3.652AspLys: 3.652 ± 0.062	4.072AspLeu: 4.072 ± 0.063	2.113AspMet: 2.113 ± 0.046	2.136AspAsn: 2.136 ± 0.046	1.734AspPro: 1.734 ± 0.042	1.053AspGln: 1.053 ± 0.031	2.743AspArg: 2.743 ± 0.054	3.009AspSer: 3.009 ± 0.052	3.202AspThr: 3.202 ± 0.05	4.034AspVal: 4.034 ± 0.061	0.543AspTrp: 0.543 ± 0.02	2.513AspTyr: 2.513 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	6.243GluAla: 6.243 ± 0.09	0.869GluCys: 0.869 ± 0.028	4.284GluAsp: 4.284 ± 0.068	7.857GluGlu: 7.857 ± 0.121	2.513GluPhe: 2.513 ± 0.052	5.011GluGly: 5.011 ± 0.071	1.439GluHis: 1.439 ± 0.04	5.283GluIle: 5.283 ± 0.085	6.196GluLys: 6.196 ± 0.075	6.959GluLeu: 6.959 ± 0.091	2.45GluMet: 2.45 ± 0.04	3.447GluAsn: 3.447 ± 0.054	2.098GluPro: 2.098 ± 0.043	2.965GluGln: 2.965 ± 0.059	3.803GluArg: 3.803 ± 0.061	3.275GluSer: 3.275 ± 0.061	3.823GluThr: 3.823 ± 0.057	4.655GluVal: 4.655 ± 0.073	0.62GluTrp: 0.62 ± 0.025	2.992GluTyr: 2.992 ± 0.056	0.0GluXaa: 0.0 ± 0.0
Phe	2.995PheAla: 2.995 ± 0.053	0.782PheCys: 0.782 ± 0.026	2.35PheAsp: 2.35 ± 0.047	2.506PheGlu: 2.506 ± 0.048	1.728PhePhe: 1.728 ± 0.038	3.046PheGly: 3.046 ± 0.057	0.796PheHis: 0.796 ± 0.027	2.856PheIle: 2.856 ± 0.058	1.887PheLys: 1.887 ± 0.043	3.781PheLeu: 3.781 ± 0.076	1.125PheMet: 1.125 ± 0.035	1.273PheAsn: 1.273 ± 0.031	1.402PhePro: 1.402 ± 0.035	1.179PheGln: 1.179 ± 0.032	1.82PheArg: 1.82 ± 0.038	2.683PheSer: 2.683 ± 0.047	2.35PheThr: 2.35 ± 0.044	2.732PheVal: 2.732 ± 0.052	0.363PheTrp: 0.363 ± 0.017	1.606PheTyr: 1.606 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	6.066GlyAla: 6.066 ± 0.086	1.415GlyCys: 1.415 ± 0.037	3.701GlyAsp: 3.701 ± 0.061	5.212GlyGlu: 5.212 ± 0.079	3.125GlyPhe: 3.125 ± 0.054	6.047GlyGly: 6.047 ± 0.088	1.34GlyHis: 1.34 ± 0.035	6.633GlyIle: 6.633 ± 0.091	5.176GlyLys: 5.176 ± 0.065	6.46GlyLeu: 6.46 ± 0.074	2.803GlyMet: 2.803 ± 0.054	2.878GlyAsn: 2.878 ± 0.048	1.69GlyPro: 1.69 ± 0.057	2.348GlyGln: 2.348 ± 0.051	4.275GlyArg: 4.275 ± 0.068	4.452GlySer: 4.452 ± 0.07	4.822GlyThr: 4.822 ± 0.075	5.363GlyVal: 5.363 ± 0.072	0.715GlyTrp: 0.715 ± 0.03	3.326GlyTyr: 3.326 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	1.148HisAla: 1.148 ± 0.027	0.321HisCys: 0.321 ± 0.016	0.876HisAsp: 0.876 ± 0.029	0.995HisGlu: 0.995 ± 0.026	0.707HisPhe: 0.707 ± 0.025	1.323HisGly: 1.323 ± 0.036	0.35HisHis: 0.35 ± 0.02	1.514HisIle: 1.514 ± 0.032	0.939HisLys: 0.939 ± 0.029	1.501HisLeu: 1.501 ± 0.035	0.676HisMet: 0.676 ± 0.027	0.648HisAsn: 0.648 ± 0.024	0.842HisPro: 0.842 ± 0.028	0.412HisGln: 0.412 ± 0.019	0.832HisArg: 0.832 ± 0.029	0.915HisSer: 0.915 ± 0.029	1.017HisThr: 1.017 ± 0.032	1.189HisVal: 1.189 ± 0.032	0.146HisTrp: 0.146 ± 0.012	0.722HisTyr: 0.722 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.524IleAla: 5.524 ± 0.068	1.314IleCys: 1.314 ± 0.038	3.818IleAsp: 3.818 ± 0.06	4.583IleGlu: 4.583 ± 0.063	2.83IlePhe: 2.83 ± 0.054	5.248IleGly: 5.248 ± 0.077	1.324IleHis: 1.324 ± 0.032	5.038IleIle: 5.038 ± 0.081	3.833IleLys: 3.833 ± 0.066	6.823IleLeu: 6.823 ± 0.088	2.08IleMet: 2.08 ± 0.045	2.43IleAsn: 2.43 ± 0.054	3.018IlePro: 3.018 ± 0.051	2.254IleGln: 2.254 ± 0.049	3.694IleArg: 3.694 ± 0.055	4.548IleSer: 4.548 ± 0.065	4.104IleThr: 4.104 ± 0.063	5.069IleVal: 5.069 ± 0.086	0.588IleTrp: 0.588 ± 0.025	2.683IleTyr: 2.683 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	5.048LysAla: 5.048 ± 0.073	0.687LysCys: 0.687 ± 0.029	3.688LysAsp: 3.688 ± 0.069	6.908LysGlu: 6.908 ± 0.092	1.653LysPhe: 1.653 ± 0.039	4.379LysGly: 4.379 ± 0.066	0.881LysHis: 0.881 ± 0.026	4.371LysIle: 4.371 ± 0.064	5.52LysLys: 5.52 ± 0.083	4.954LysLeu: 4.954 ± 0.066	2.187LysMet: 2.187 ± 0.038	2.969LysAsn: 2.969 ± 0.055	1.8LysPro: 1.8 ± 0.039	1.941LysGln: 1.941 ± 0.04	3.103LysArg: 3.103 ± 0.053	3.045LysSer: 3.045 ± 0.058	3.37LysThr: 3.37 ± 0.053	4.265LysVal: 4.265 ± 0.058	0.555LysTrp: 0.555 ± 0.022	2.632LysTyr: 2.632 ± 0.049	0.0LysXaa: 0.0 ± 0.0
Leu	7.096LeuAla: 7.096 ± 0.082	1.595LeuCys: 1.595 ± 0.039	5.074LeuAsp: 5.074 ± 0.072	6.218LeuGlu: 6.218 ± 0.079	3.716LeuPhe: 3.716 ± 0.068	6.297LeuGly: 6.297 ± 0.088	1.498LeuHis: 1.498 ± 0.039	5.787LeuIle: 5.787 ± 0.074	6.152LeuLys: 6.152 ± 0.074	8.582LeuLeu: 8.582 ± 0.126	2.68LeuMet: 2.68 ± 0.05	3.462LeuAsn: 3.462 ± 0.052	3.579LeuPro: 3.579 ± 0.054	2.473LeuGln: 2.473 ± 0.054	4.036LeuArg: 4.036 ± 0.058	6.245LeuSer: 6.245 ± 0.087	5.159LeuThr: 5.159 ± 0.078	5.374LeuVal: 5.374 ± 0.083	0.685LeuTrp: 0.685 ± 0.029	3.368LeuTyr: 3.368 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.541MetAla: 2.541 ± 0.047	0.425MetCys: 0.425 ± 0.019	1.968MetAsp: 1.968 ± 0.039	2.763MetGlu: 2.763 ± 0.053	0.985MetPhe: 0.985 ± 0.032	2.266MetGly: 2.266 ± 0.047	0.478MetHis: 0.478 ± 0.018	2.154MetIle: 2.154 ± 0.044	2.663MetLys: 2.663 ± 0.052	2.913MetLeu: 2.913 ± 0.05	0.993MetMet: 0.993 ± 0.031	1.522MetAsn: 1.522 ± 0.038	1.178MetPro: 1.178 ± 0.03	1.045MetGln: 1.045 ± 0.03	1.4MetArg: 1.4 ± 0.033	1.898MetSer: 1.898 ± 0.042	1.883MetThr: 1.883 ± 0.04	1.877MetVal: 1.877 ± 0.039	0.253MetTrp: 0.253 ± 0.015	1.007MetTyr: 1.007 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	2.922AsnAla: 2.922 ± 0.05	0.608AsnCys: 0.608 ± 0.022	1.854AsnAsp: 1.854 ± 0.049	2.564AsnGlu: 2.564 ± 0.048	1.338AsnPhe: 1.338 ± 0.037	3.088AsnGly: 3.088 ± 0.06	0.639AsnHis: 0.639 ± 0.021	3.266AsnIle: 3.266 ± 0.061	2.219AsnLys: 2.219 ± 0.04	3.19AsnLeu: 3.19 ± 0.05	1.396AsnMet: 1.396 ± 0.036	1.583AsnAsn: 1.583 ± 0.046	1.651AsnPro: 1.651 ± 0.039	0.984AsnGln: 0.984 ± 0.033	1.876AsnArg: 1.876 ± 0.039	1.991AsnSer: 1.991 ± 0.046	2.055AsnThr: 2.055 ± 0.04	2.791AsnVal: 2.791 ± 0.042	0.389AsnTrp: 0.389 ± 0.018	1.596AsnTyr: 1.596 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	3.076ProAla: 3.076 ± 0.064	0.546ProCys: 0.546 ± 0.024	2.52ProAsp: 2.52 ± 0.047	3.251ProGlu: 3.251 ± 0.062	1.497ProPhe: 1.497 ± 0.031	2.86ProGly: 2.86 ± 0.056	0.606ProHis: 0.606 ± 0.022	1.689ProIle: 1.689 ± 0.04	1.69ProLys: 1.69 ± 0.039	2.813ProLeu: 2.813 ± 0.047	0.812ProMet: 0.812 ± 0.025	1.046ProAsn: 1.046 ± 0.031	0.921ProPro: 0.921 ± 0.04	1.062ProGln: 1.062 ± 0.038	1.1ProArg: 1.1 ± 0.031	1.888ProSer: 1.888 ± 0.043	1.354ProThr: 1.354 ± 0.038	3.359ProVal: 3.359 ± 0.06	0.311ProTrp: 0.311 ± 0.018	1.485ProTyr: 1.485 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.301GlnAla: 2.301 ± 0.048	0.392GlnCys: 0.392 ± 0.017	1.452GlnAsp: 1.452 ± 0.034	2.49GlnGlu: 2.49 ± 0.05	1.184GlnPhe: 1.184 ± 0.029	1.997GlnGly: 1.997 ± 0.043	0.387GlnHis: 0.387 ± 0.018	2.339GlnIle: 2.339 ± 0.044	2.346GlnLys: 2.346 ± 0.047	2.564GlnLeu: 2.564 ± 0.051	1.185GlnMet: 1.185 ± 0.034	1.403GlnAsn: 1.403 ± 0.041	0.903GlnPro: 0.903 ± 0.029	1.034GlnGln: 1.034 ± 0.032	1.323GlnArg: 1.323 ± 0.035	1.561GlnSer: 1.561 ± 0.039	1.53GlnThr: 1.53 ± 0.033	1.885GlnVal: 1.885 ± 0.04	0.288GlnTrp: 0.288 ± 0.018	1.232GlnTyr: 1.232 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	3.2ArgAla: 3.2 ± 0.061	0.649ArgCys: 0.649 ± 0.023	2.366ArgAsp: 2.366 ± 0.045	4.298ArgGlu: 4.298 ± 0.07	1.933ArgPhe: 1.933 ± 0.038	3.0ArgGly: 3.0 ± 0.049	0.986ArgHis: 0.986 ± 0.03	3.587ArgIle: 3.587 ± 0.05	3.574ArgLys: 3.574 ± 0.06	4.551ArgLeu: 4.551 ± 0.067	1.775ArgMet: 1.775 ± 0.034	1.878ArgAsn: 1.878 ± 0.037	1.69ArgPro: 1.69 ± 0.044	2.07ArgGln: 2.07 ± 0.043	3.105ArgArg: 3.105 ± 0.062	2.509ArgSer: 2.509 ± 0.047	2.573ArgThr: 2.573 ± 0.047	2.723ArgVal: 2.723 ± 0.052	0.425ArgTrp: 0.425 ± 0.019	1.924ArgTyr: 1.924 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	4.53SerAla: 4.53 ± 0.07	0.876SerCys: 0.876 ± 0.03	3.16SerAsp: 3.16 ± 0.06	3.61SerGlu: 3.61 ± 0.059	2.639SerPhe: 2.639 ± 0.053	5.533SerGly: 5.533 ± 0.082	0.993SerHis: 0.993 ± 0.031	3.743SerIle: 3.743 ± 0.058	2.803SerLys: 2.803 ± 0.052	5.086SerLeu: 5.086 ± 0.079	1.779SerMet: 1.779 ± 0.04	1.902SerAsn: 1.902 ± 0.047	1.859SerPro: 1.859 ± 0.038	1.674SerGln: 1.674 ± 0.044	3.11SerArg: 3.11 ± 0.054	3.347SerSer: 3.347 ± 0.055	2.542SerThr: 2.542 ± 0.051	4.585SerVal: 4.585 ± 0.067	0.49SerTrp: 0.49 ± 0.02	2.335SerTyr: 2.335 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	5.03ThrAla: 5.03 ± 0.074	0.732ThrCys: 0.732 ± 0.025	3.279ThrAsp: 3.279 ± 0.056	3.869ThrGlu: 3.869 ± 0.059	2.177ThrPhe: 2.177 ± 0.041	5.266ThrGly: 5.266 ± 0.086	0.81ThrHis: 0.81 ± 0.026	3.364ThrIle: 3.364 ± 0.052	2.902ThrLys: 2.902 ± 0.044	4.769ThrLeu: 4.769 ± 0.074	1.417ThrMet: 1.417 ± 0.03	1.676ThrAsn: 1.676 ± 0.04	2.149ThrPro: 2.149 ± 0.038	1.294ThrGln: 1.294 ± 0.036	1.888ThrArg: 1.888 ± 0.037	2.726ThrSer: 2.726 ± 0.048	2.562ThrThr: 2.562 ± 0.052	4.794ThrVal: 4.794 ± 0.074	0.447ThrTrp: 0.447 ± 0.019	2.095ThrTyr: 2.095 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.707ValAla: 4.707 ± 0.072	1.379ValCys: 1.379 ± 0.032	3.736ValAsp: 3.736 ± 0.052	4.634ValGlu: 4.634 ± 0.067	3.128ValPhe: 3.128 ± 0.059	4.416ValGly: 4.416 ± 0.065	1.218ValHis: 1.218 ± 0.031	5.481ValIle: 5.481 ± 0.078	4.667ValLys: 4.667 ± 0.072	7.157ValLeu: 7.157 ± 0.088	2.301ValMet: 2.301 ± 0.04	2.886ValAsn: 2.886 ± 0.052	2.827ValPro: 2.827 ± 0.053	1.971ValGln: 1.971 ± 0.043	3.497ValArg: 3.497 ± 0.058	4.726ValSer: 4.726 ± 0.069	4.516ValThr: 4.516 ± 0.073	4.863ValVal: 4.863 ± 0.077	0.636ValTrp: 0.636 ± 0.026	2.85ValTyr: 2.85 ± 0.05	0.0ValXaa: 0.0 ± 0.0
Trp	0.54TrpAla: 0.54 ± 0.024	0.139TrpCys: 0.139 ± 0.013	0.509TrpAsp: 0.509 ± 0.022	0.61TrpGlu: 0.61 ± 0.024	0.38TrpPhe: 0.38 ± 0.021	0.663TrpGly: 0.663 ± 0.025	0.161TrpHis: 0.161 ± 0.011	0.595TrpIle: 0.595 ± 0.025	0.66TrpLys: 0.66 ± 0.026	0.822TrpLeu: 0.822 ± 0.031	0.316TrpMet: 0.316 ± 0.018	0.448TrpAsn: 0.448 ± 0.021	0.218TrpPro: 0.218 ± 0.014	0.327TrpGln: 0.327 ± 0.019	0.374TrpArg: 0.374 ± 0.018	0.459TrpSer: 0.459 ± 0.02	0.414TrpThr: 0.414 ± 0.018	0.494TrpVal: 0.494 ± 0.02	0.097TrpTrp: 0.097 ± 0.01	0.361TrpTyr: 0.361 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.798TyrAla: 2.798 ± 0.048	0.611TyrCys: 0.611 ± 0.024	2.464TyrAsp: 2.464 ± 0.052	3.183TyrGlu: 3.183 ± 0.05	1.636TyrPhe: 1.636 ± 0.037	3.08TyrGly: 3.08 ± 0.046	0.78TyrHis: 0.78 ± 0.027	2.915TyrIle: 2.915 ± 0.045	2.193TyrLys: 2.193 ± 0.048	3.464TyrLeu: 3.464 ± 0.06	1.24TyrMet: 1.24 ± 0.031	1.627TyrAsn: 1.627 ± 0.037	1.434TyrPro: 1.434 ± 0.036	1.085TyrGln: 1.085 ± 0.034	2.182TyrArg: 2.182 ± 0.042	2.237TyrSer: 2.237 ± 0.042	2.288TyrThr: 2.288 ± 0.051	2.613TyrVal: 2.613 ± 0.046	0.322TyrTrp: 0.322 ± 0.018	1.853TyrTyr: 1.853 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3971 proteins (1201420 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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