Amino acid dipepetide frequency for Pseudochrobactrum asaccharolyticum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.143AlaAla: 13.143 ± 0.15	0.881AlaCys: 0.881 ± 0.024	6.468AlaAsp: 6.468 ± 0.199	6.991AlaGlu: 6.991 ± 0.094	4.101AlaPhe: 4.101 ± 0.064	9.14AlaGly: 9.14 ± 0.088	1.999AlaHis: 1.999 ± 0.043	6.328AlaIle: 6.328 ± 0.071	4.788AlaLys: 4.788 ± 0.075	11.944AlaLeu: 11.944 ± 0.122	3.292AlaMet: 3.292 ± 0.051	3.153AlaAsn: 3.153 ± 0.053	4.466AlaPro: 4.466 ± 0.083	4.402AlaGln: 4.402 ± 0.067	5.997AlaArg: 5.997 ± 0.081	5.992AlaSer: 5.992 ± 0.064	5.392AlaThr: 5.392 ± 0.079	7.668AlaVal: 7.668 ± 0.086	1.112AlaTrp: 1.112 ± 0.03	2.713AlaTyr: 2.713 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.852CysAla: 0.852 ± 0.027	0.104CysCys: 0.104 ± 0.009	0.443CysAsp: 0.443 ± 0.018	0.446CysGlu: 0.446 ± 0.019	0.363CysPhe: 0.363 ± 0.017	0.818CysGly: 0.818 ± 0.024	0.232CysHis: 0.232 ± 0.013	0.466CysIle: 0.466 ± 0.019	0.284CysLys: 0.284 ± 0.016	0.776CysLeu: 0.776 ± 0.025	0.182CysMet: 0.182 ± 0.011	0.261CysAsn: 0.261 ± 0.015	0.371CysPro: 0.371 ± 0.017	0.23CysGln: 0.23 ± 0.014	0.506CysArg: 0.506 ± 0.021	0.502CysSer: 0.502 ± 0.02	0.447CysThr: 0.447 ± 0.018	0.518CysVal: 0.518 ± 0.02	0.098CysTrp: 0.098 ± 0.009	0.197CysTyr: 0.197 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.172AspAla: 6.172 ± 0.205	0.434AspCys: 0.434 ± 0.02	3.049AspAsp: 3.049 ± 0.061	3.449AspGlu: 3.449 ± 0.056	2.262AspPhe: 2.262 ± 0.041	4.596AspGly: 4.596 ± 0.073	1.256AspHis: 1.256 ± 0.036	3.652AspIle: 3.652 ± 0.05	2.525AspLys: 2.525 ± 0.046	5.505AspLeu: 5.505 ± 0.066	1.596AspMet: 1.596 ± 0.037	1.905AspAsn: 1.905 ± 0.039	2.68AspPro: 2.68 ± 0.039	1.976AspGln: 1.976 ± 0.042	3.327AspArg: 3.327 ± 0.051	2.286AspSer: 2.286 ± 0.043	2.749AspThr: 2.749 ± 0.065	3.876AspVal: 3.876 ± 0.057	0.881AspTrp: 0.881 ± 0.026	1.838AspTyr: 1.838 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	6.747GluAla: 6.747 ± 0.082	0.363GluCys: 0.363 ± 0.017	2.834GluAsp: 2.834 ± 0.051	3.236GluGlu: 3.236 ± 0.064	1.948GluPhe: 1.948 ± 0.037	3.973GluGly: 3.973 ± 0.058	1.168GluHis: 1.168 ± 0.028	3.677GluIle: 3.677 ± 0.053	3.211GluLys: 3.211 ± 0.049	5.379GluLeu: 5.379 ± 0.065	1.622GluMet: 1.622 ± 0.033	2.331GluAsn: 2.331 ± 0.044	2.469GluPro: 2.469 ± 0.042	2.646GluGln: 2.646 ± 0.055	4.003GluArg: 4.003 ± 0.064	2.333GluSer: 2.333 ± 0.045	3.582GluThr: 3.582 ± 0.053	3.647GluVal: 3.647 ± 0.056	0.735GluTrp: 0.735 ± 0.024	1.182GluTyr: 1.182 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.237PheAla: 4.237 ± 0.064	0.408PheCys: 0.408 ± 0.017	2.637PheAsp: 2.637 ± 0.047	2.08PheGlu: 2.08 ± 0.039	1.576PhePhe: 1.576 ± 0.038	3.542PheGly: 3.542 ± 0.057	0.737PheHis: 0.737 ± 0.021	2.478PheIle: 2.478 ± 0.048	1.36PheLys: 1.36 ± 0.031	3.443PheLeu: 3.443 ± 0.062	0.972PheMet: 0.972 ± 0.028	1.454PheAsn: 1.454 ± 0.036	1.516PhePro: 1.516 ± 0.033	1.16PheGln: 1.16 ± 0.03	2.08PheArg: 2.08 ± 0.038	2.774PheSer: 2.774 ± 0.052	2.445PheThr: 2.445 ± 0.06	2.568PheVal: 2.568 ± 0.049	0.586PheTrp: 0.586 ± 0.021	1.127PheTyr: 1.127 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	7.636GlyAla: 7.636 ± 0.103	0.769GlyCys: 0.769 ± 0.025	3.886GlyAsp: 3.886 ± 0.059	4.443GlyGlu: 4.443 ± 0.065	3.651GlyPhe: 3.651 ± 0.055	6.126GlyGly: 6.126 ± 0.112	1.686GlyHis: 1.686 ± 0.04	4.974GlyIle: 4.974 ± 0.064	4.084GlyLys: 4.084 ± 0.066	8.039GlyLeu: 8.039 ± 0.098	2.207GlyMet: 2.207 ± 0.049	2.749GlyAsn: 2.749 ± 0.069	2.33GlyPro: 2.33 ± 0.047	2.974GlyGln: 2.974 ± 0.053	4.517GlyArg: 4.517 ± 0.056	4.809GlySer: 4.809 ± 0.071	4.538GlyThr: 4.538 ± 0.085	5.348GlyVal: 5.348 ± 0.066	1.149GlyTrp: 1.149 ± 0.031	2.349GlyTyr: 2.349 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	1.92HisAla: 1.92 ± 0.041	0.222HisCys: 0.222 ± 0.012	1.218HisAsp: 1.218 ± 0.031	1.109HisGlu: 1.109 ± 0.028	0.915HisPhe: 0.915 ± 0.031	1.681HisGly: 1.681 ± 0.037	0.575HisHis: 0.575 ± 0.026	1.295HisIle: 1.295 ± 0.032	0.791HisLys: 0.791 ± 0.021	1.983HisLeu: 1.983 ± 0.046	0.547HisMet: 0.547 ± 0.022	0.689HisAsn: 0.689 ± 0.025	1.146HisPro: 1.146 ± 0.029	0.706HisGln: 0.706 ± 0.028	1.132HisArg: 1.132 ± 0.035	1.154HisSer: 1.154 ± 0.031	0.905HisThr: 0.905 ± 0.028	1.304HisVal: 1.304 ± 0.031	0.303HisTrp: 0.303 ± 0.016	0.677HisTyr: 0.677 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	7.64IleAla: 7.64 ± 0.084	0.611IleCys: 0.611 ± 0.022	3.704IleAsp: 3.704 ± 0.055	3.769IleGlu: 3.769 ± 0.056	2.202IlePhe: 2.202 ± 0.045	5.25IleGly: 5.25 ± 0.069	1.027IleHis: 1.027 ± 0.029	3.756IleIle: 3.756 ± 0.056	2.196IleLys: 2.196 ± 0.043	5.396IleLeu: 5.396 ± 0.075	1.348IleMet: 1.348 ± 0.033	2.175IleAsn: 2.175 ± 0.039	2.577IlePro: 2.577 ± 0.044	1.638IleGln: 1.638 ± 0.034	3.67IleArg: 3.67 ± 0.048	4.042IleSer: 4.042 ± 0.054	3.643IleThr: 3.643 ± 0.064	4.286IleVal: 4.286 ± 0.063	0.668IleTrp: 0.668 ± 0.023	1.588IleTyr: 1.588 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	4.994LysAla: 4.994 ± 0.079	0.214LysCys: 0.214 ± 0.012	2.302LysAsp: 2.302 ± 0.044	2.142LysGlu: 2.142 ± 0.044	1.278LysPhe: 1.278 ± 0.035	3.033LysGly: 3.033 ± 0.05	0.83LysHis: 0.83 ± 0.026	2.756LysIle: 2.756 ± 0.048	2.07LysLys: 2.07 ± 0.052	4.349LysLeu: 4.349 ± 0.063	1.133LysMet: 1.133 ± 0.026	1.719LysAsn: 1.719 ± 0.04	2.589LysPro: 2.589 ± 0.046	1.775LysGln: 1.775 ± 0.04	2.677LysArg: 2.677 ± 0.048	2.601LysSer: 2.601 ± 0.044	2.914LysThr: 2.914 ± 0.045	2.682LysVal: 2.682 ± 0.048	0.464LysTrp: 0.464 ± 0.021	0.938LysTyr: 0.938 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	11.001LeuAla: 11.001 ± 0.093	0.889LeuCys: 0.889 ± 0.027	5.38LeuAsp: 5.38 ± 0.065	5.16LeuGlu: 5.16 ± 0.071	3.74LeuPhe: 3.74 ± 0.07	7.309LeuGly: 7.309 ± 0.084	1.89LeuHis: 1.89 ± 0.036	6.22LeuIle: 6.22 ± 0.084	4.553LeuLys: 4.553 ± 0.061	9.544LeuLeu: 9.544 ± 0.107	2.551LeuMet: 2.551 ± 0.045	3.627LeuAsn: 3.627 ± 0.057	5.056LeuPro: 5.056 ± 0.07	3.513LeuGln: 3.513 ± 0.058	5.95LeuArg: 5.95 ± 0.077	7.304LeuSer: 7.304 ± 0.088	6.008LeuThr: 6.008 ± 0.069	6.32LeuVal: 6.32 ± 0.087	1.094LeuTrp: 1.094 ± 0.031	2.335LeuTyr: 2.335 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	2.91MetAla: 2.91 ± 0.05	0.17MetCys: 0.17 ± 0.012	1.189MetAsp: 1.189 ± 0.033	1.192MetGlu: 1.192 ± 0.031	0.862MetPhe: 0.862 ± 0.028	1.713MetGly: 1.713 ± 0.036	0.503MetHis: 0.503 ± 0.019	1.741MetIle: 1.741 ± 0.04	1.263MetLys: 1.263 ± 0.033	2.719MetLeu: 2.719 ± 0.048	0.819MetMet: 0.819 ± 0.026	0.962MetAsn: 0.962 ± 0.026	1.461MetPro: 1.461 ± 0.033	1.184MetGln: 1.184 ± 0.032	1.824MetArg: 1.824 ± 0.037	2.025MetSer: 2.025 ± 0.042	1.902MetThr: 1.902 ± 0.036	1.74MetVal: 1.74 ± 0.036	0.214MetTrp: 0.214 ± 0.014	0.375MetTyr: 0.375 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.67AsnAla: 3.67 ± 0.055	0.284AsnCys: 0.284 ± 0.016	1.911AsnAsp: 1.911 ± 0.034	1.68AsnGlu: 1.68 ± 0.04	1.306AsnPhe: 1.306 ± 0.033	3.087AsnGly: 3.087 ± 0.07	0.689AsnHis: 0.689 ± 0.023	2.258AsnIle: 2.258 ± 0.045	1.373AsnLys: 1.373 ± 0.044	3.189AsnLeu: 3.189 ± 0.054	0.878AsnMet: 0.878 ± 0.026	1.36AsnAsn: 1.36 ± 0.042	2.064AsnPro: 2.064 ± 0.042	1.184AsnGln: 1.184 ± 0.032	2.046AsnArg: 2.046 ± 0.041	1.947AsnSer: 1.947 ± 0.041	1.82AsnThr: 1.82 ± 0.044	2.195AsnVal: 2.195 ± 0.046	0.599AsnTrp: 0.599 ± 0.022	1.004AsnTyr: 1.004 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	5.217ProAla: 5.217 ± 0.086	0.275ProCys: 0.275 ± 0.013	3.263ProAsp: 3.263 ± 0.05	3.572ProGlu: 3.572 ± 0.052	1.869ProPhe: 1.869 ± 0.043	2.616ProGly: 2.616 ± 0.044	1.085ProHis: 1.085 ± 0.026	1.972ProIle: 1.972 ± 0.047	1.79ProLys: 1.79 ± 0.039	4.436ProLeu: 4.436 ± 0.064	1.037ProMet: 1.037 ± 0.029	1.416ProAsn: 1.416 ± 0.031	1.626ProPro: 1.626 ± 0.043	2.053ProGln: 2.053 ± 0.04	2.059ProArg: 2.059 ± 0.043	2.613ProSer: 2.613 ± 0.041	2.052ProThr: 2.052 ± 0.048	4.527ProVal: 4.527 ± 0.059	0.587ProTrp: 0.587 ± 0.022	1.3ProTyr: 1.3 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.477GlnAla: 4.477 ± 0.066	0.234GlnCys: 0.234 ± 0.016	1.884GlnAsp: 1.884 ± 0.037	1.884GlnGlu: 1.884 ± 0.044	1.329GlnPhe: 1.329 ± 0.03	2.658GlnGly: 2.658 ± 0.045	0.796GlnHis: 0.796 ± 0.028	2.328GlnIle: 2.328 ± 0.042	1.692GlnLys: 1.692 ± 0.039	3.478GlnLeu: 3.478 ± 0.064	1.066GlnMet: 1.066 ± 0.03	1.422GlnAsn: 1.422 ± 0.034	1.854GlnPro: 1.854 ± 0.044	1.749GlnGln: 1.749 ± 0.038	2.439GlnArg: 2.439 ± 0.045	2.362GlnSer: 2.362 ± 0.046	2.121GlnThr: 2.121 ± 0.048	2.405GlnVal: 2.405 ± 0.039	0.479GlnTrp: 0.479 ± 0.019	0.817GlnTyr: 0.817 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	5.427ArgAla: 5.427 ± 0.071	0.422ArgCys: 0.422 ± 0.018	3.365ArgAsp: 3.365 ± 0.056	3.567ArgGlu: 3.567 ± 0.058	2.694ArgPhe: 2.694 ± 0.049	3.673ArgGly: 3.673 ± 0.058	1.39ArgHis: 1.39 ± 0.038	3.912ArgIle: 3.912 ± 0.052	2.692ArgLys: 2.692 ± 0.044	6.327ArgLeu: 6.327 ± 0.078	1.686ArgMet: 1.686 ± 0.033	2.169ArgAsn: 2.169 ± 0.044	2.499ArgPro: 2.499 ± 0.048	2.487ArgGln: 2.487 ± 0.039	3.712ArgArg: 3.712 ± 0.067	3.508ArgSer: 3.508 ± 0.054	2.896ArgThr: 2.896 ± 0.051	3.784ArgVal: 3.784 ± 0.061	0.734ArgTrp: 0.734 ± 0.025	1.685ArgTyr: 1.685 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.447SerAla: 6.447 ± 0.08	0.446SerCys: 0.446 ± 0.019	3.469SerAsp: 3.469 ± 0.049	3.314SerGlu: 3.314 ± 0.046	2.701SerPhe: 2.701 ± 0.05	6.167SerGly: 6.167 ± 0.09	1.26SerHis: 1.26 ± 0.029	3.265SerIle: 3.265 ± 0.058	2.268SerLys: 2.268 ± 0.043	5.967SerLeu: 5.967 ± 0.071	1.54SerMet: 1.54 ± 0.033	1.875SerAsn: 1.875 ± 0.039	2.513SerPro: 2.513 ± 0.04	1.977SerGln: 1.977 ± 0.04	3.37SerArg: 3.37 ± 0.061	3.561SerSer: 3.561 ± 0.062	2.904SerThr: 2.904 ± 0.051	4.534SerVal: 4.534 ± 0.059	0.842SerTrp: 0.842 ± 0.027	1.725SerTyr: 1.725 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	6.215ThrAla: 6.215 ± 0.082	0.412ThrCys: 0.412 ± 0.018	3.114ThrAsp: 3.114 ± 0.063	3.035ThrGlu: 3.035 ± 0.054	1.983ThrPhe: 1.983 ± 0.049	5.262ThrGly: 5.262 ± 0.075	1.07ThrHis: 1.07 ± 0.028	3.74ThrIle: 3.74 ± 0.062	1.983ThrLys: 1.983 ± 0.041	5.745ThrLeu: 5.745 ± 0.076	1.362ThrMet: 1.362 ± 0.027	1.662ThrAsn: 1.662 ± 0.035	3.103ThrPro: 3.103 ± 0.056	1.842ThrGln: 1.842 ± 0.039	2.816ThrArg: 2.816 ± 0.051	3.169ThrSer: 3.169 ± 0.052	3.269ThrThr: 3.269 ± 0.067	4.448ThrVal: 4.448 ± 0.085	0.563ThrTrp: 0.563 ± 0.023	1.437ThrTyr: 1.437 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	7.562ValAla: 7.562 ± 0.084	0.582ValCys: 0.582 ± 0.023	3.601ValAsp: 3.601 ± 0.061	4.061ValGlu: 4.061 ± 0.051	2.779ValPhe: 2.779 ± 0.051	4.57ValGly: 4.57 ± 0.068	1.264ValHis: 1.264 ± 0.032	4.371ValIle: 4.371 ± 0.063	2.977ValLys: 2.977 ± 0.054	7.092ValLeu: 7.092 ± 0.079	1.986ValMet: 1.986 ± 0.037	2.174ValAsn: 2.174 ± 0.042	3.285ValPro: 3.285 ± 0.048	2.269ValGln: 2.269 ± 0.041	3.893ValArg: 3.893 ± 0.06	4.736ValSer: 4.736 ± 0.066	4.563ValThr: 4.563 ± 0.072	5.105ValVal: 5.105 ± 0.076	0.82ValTrp: 0.82 ± 0.022	1.645ValTyr: 1.645 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.07TrpAla: 1.07 ± 0.032	0.125TrpCys: 0.125 ± 0.009	0.602TrpAsp: 0.602 ± 0.022	0.545TrpGlu: 0.545 ± 0.023	0.535TrpPhe: 0.535 ± 0.019	0.836TrpGly: 0.836 ± 0.027	0.291TrpHis: 0.291 ± 0.014	0.628TrpIle: 0.628 ± 0.022	0.528TrpLys: 0.528 ± 0.02	1.592TrpLeu: 1.592 ± 0.034	0.338TrpMet: 0.338 ± 0.019	0.487TrpAsn: 0.487 ± 0.023	0.604TrpPro: 0.604 ± 0.022	0.653TrpGln: 0.653 ± 0.022	0.884TrpArg: 0.884 ± 0.028	0.827TrpSer: 0.827 ± 0.036	0.667TrpThr: 0.667 ± 0.024	0.751TrpVal: 0.751 ± 0.027	0.197TrpTrp: 0.197 ± 0.01	0.336TrpTyr: 0.336 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.633TyrAla: 2.633 ± 0.044	0.249TyrCys: 0.249 ± 0.014	1.692TyrAsp: 1.692 ± 0.039	1.41TyrGlu: 1.41 ± 0.033	1.088TyrPhe: 1.088 ± 0.026	2.211TyrGly: 2.211 ± 0.045	0.524TyrHis: 0.524 ± 0.022	1.37TyrIle: 1.37 ± 0.029	1.035TyrLys: 1.035 ± 0.031	2.544TyrLeu: 2.544 ± 0.044	0.607TyrMet: 0.607 ± 0.021	0.955TyrAsn: 0.955 ± 0.031	1.157TyrPro: 1.157 ± 0.033	1.053TyrGln: 1.053 ± 0.027	1.726TyrArg: 1.726 ± 0.044	1.599TyrSer: 1.599 ± 0.037	1.413TyrThr: 1.413 ± 0.033	1.629TyrVal: 1.629 ± 0.033	0.371TyrTrp: 0.371 ± 0.017	0.78TyrTyr: 0.78 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4256 proteins (1333084 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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