Amino acid dipepetide frequency for Cordoba virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.565AlaAla: 2.565 ± 0.0
0.428AlaCys: 0.428 ± 0.0
2.565AlaAsp: 2.565 ± 0.0
3.848AlaGlu: 3.848 ± 0.0
2.138AlaPhe: 2.138 ± 0.0
1.71AlaGly: 1.71 ± 0.0
0.855AlaHis: 0.855 ± 0.0
3.42AlaIle: 3.42 ± 0.0
4.703AlaLys: 4.703 ± 0.0
7.696AlaLeu: 7.696 ± 0.0
2.565AlaMet: 2.565 ± 0.0
6.841AlaAsn: 6.841 ± 0.0
0.855AlaPro: 0.855 ± 0.0
0.428AlaGln: 0.428 ± 0.0
2.138AlaArg: 2.138 ± 0.0
3.42AlaSer: 3.42 ± 0.0
1.283AlaThr: 1.283 ± 0.0
2.138AlaVal: 2.138 ± 0.0
0.428AlaTrp: 0.428 ± 0.0
2.565AlaTyr: 2.565 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.855CysAsp: 0.855 ± 0.0
1.283CysGlu: 1.283 ± 0.0
0.855CysPhe: 0.855 ± 0.0
1.283CysGly: 1.283 ± 0.0
0.428CysHis: 0.428 ± 0.0
0.855CysIle: 0.855 ± 0.0
2.138CysLys: 2.138 ± 0.0
1.71CysLeu: 1.71 ± 0.0
0.428CysMet: 0.428 ± 0.0
1.71CysAsn: 1.71 ± 0.0
0.855CysPro: 0.855 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.855CysArg: 0.855 ± 0.0
1.283CysSer: 1.283 ± 0.0
1.283CysThr: 1.283 ± 0.0
0.855CysVal: 0.855 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.428CysTyr: 0.428 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.703AspAla: 4.703 ± 0.0
0.855AspCys: 0.855 ± 0.0
4.703AspAsp: 4.703 ± 0.0
6.413AspGlu: 6.413 ± 0.0
3.848AspPhe: 3.848 ± 0.0
2.565AspGly: 2.565 ± 0.0
1.283AspHis: 1.283 ± 0.0
4.275AspIle: 4.275 ± 0.0
5.985AspLys: 5.985 ± 0.0
2.565AspLeu: 2.565 ± 0.0
2.993AspMet: 2.993 ± 0.0
4.703AspAsn: 4.703 ± 0.0
1.283AspPro: 1.283 ± 0.0
2.138AspGln: 2.138 ± 0.0
2.993AspArg: 2.993 ± 0.0
3.42AspSer: 3.42 ± 0.0
2.565AspThr: 2.565 ± 0.0
5.558AspVal: 5.558 ± 0.0
0.855AspTrp: 0.855 ± 0.0
2.138AspTyr: 2.138 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.275GluAla: 4.275 ± 0.0
1.283GluCys: 1.283 ± 0.0
3.848GluAsp: 3.848 ± 0.0
6.413GluGlu: 6.413 ± 0.0
4.703GluPhe: 4.703 ± 0.0
1.71GluGly: 1.71 ± 0.0
1.283GluHis: 1.283 ± 0.0
8.123GluIle: 8.123 ± 0.0
5.985GluLys: 5.985 ± 0.0
5.558GluLeu: 5.558 ± 0.0
2.993GluMet: 2.993 ± 0.0
5.558GluAsn: 5.558 ± 0.0
1.283GluPro: 1.283 ± 0.0
1.283GluGln: 1.283 ± 0.0
4.703GluArg: 4.703 ± 0.0
3.42GluSer: 3.42 ± 0.0
5.13GluThr: 5.13 ± 0.0
5.558GluVal: 5.558 ± 0.0
0.428GluTrp: 0.428 ± 0.0
4.703GluTyr: 4.703 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.565PheAla: 2.565 ± 0.0
1.71PheCys: 1.71 ± 0.0
5.985PheAsp: 5.985 ± 0.0
4.275PheGlu: 4.275 ± 0.0
1.283PhePhe: 1.283 ± 0.0
2.565PheGly: 2.565 ± 0.0
0.855PheHis: 0.855 ± 0.0
2.565PheIle: 2.565 ± 0.0
2.993PheLys: 2.993 ± 0.0
5.13PheLeu: 5.13 ± 0.0
0.0PheMet: 0.0 ± 0.0
3.848PheAsn: 3.848 ± 0.0
0.0PhePro: 0.0 ± 0.0
0.428PheGln: 0.428 ± 0.0
2.138PheArg: 2.138 ± 0.0
3.848PheSer: 3.848 ± 0.0
2.565PheThr: 2.565 ± 0.0
3.848PheVal: 3.848 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.71PheTyr: 1.71 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.71GlyAla: 1.71 ± 0.0
1.283GlyCys: 1.283 ± 0.0
5.558GlyAsp: 5.558 ± 0.0
2.565GlyGlu: 2.565 ± 0.0
0.855GlyPhe: 0.855 ± 0.0
1.283GlyGly: 1.283 ± 0.0
0.855GlyHis: 0.855 ± 0.0
4.703GlyIle: 4.703 ± 0.0
3.42GlyLys: 3.42 ± 0.0
3.42GlyLeu: 3.42 ± 0.0
0.428GlyMet: 0.428 ± 0.0
4.275GlyAsn: 4.275 ± 0.0
0.855GlyPro: 0.855 ± 0.0
0.855GlyGln: 0.855 ± 0.0
1.283GlyArg: 1.283 ± 0.0
2.993GlySer: 2.993 ± 0.0
2.565GlyThr: 2.565 ± 0.0
2.565GlyVal: 2.565 ± 0.0
0.428GlyTrp: 0.428 ± 0.0
1.283GlyTyr: 1.283 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.71HisAla: 1.71 ± 0.0
0.428HisCys: 0.428 ± 0.0
1.283HisAsp: 1.283 ± 0.0
1.71HisGlu: 1.71 ± 0.0
2.138HisPhe: 2.138 ± 0.0
0.428HisGly: 0.428 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.565HisIle: 2.565 ± 0.0
1.283HisLys: 1.283 ± 0.0
1.71HisLeu: 1.71 ± 0.0
0.428HisMet: 0.428 ± 0.0
2.138HisAsn: 2.138 ± 0.0
0.855HisPro: 0.855 ± 0.0
0.428HisGln: 0.428 ± 0.0
1.283HisArg: 1.283 ± 0.0
0.855HisSer: 0.855 ± 0.0
1.283HisThr: 1.283 ± 0.0
0.428HisVal: 0.428 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.428HisTyr: 0.428 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.848IleAla: 3.848 ± 0.0
1.71IleCys: 1.71 ± 0.0
4.703IleAsp: 4.703 ± 0.0
6.413IleGlu: 6.413 ± 0.0
2.138IlePhe: 2.138 ± 0.0
2.565IleGly: 2.565 ± 0.0
1.71IleHis: 1.71 ± 0.0
3.42IleIle: 3.42 ± 0.0
8.551IleLys: 8.551 ± 0.0
5.558IleLeu: 5.558 ± 0.0
1.71IleMet: 1.71 ± 0.0
5.558IleAsn: 5.558 ± 0.0
1.283IlePro: 1.283 ± 0.0
1.283IleGln: 1.283 ± 0.0
3.42IleArg: 3.42 ± 0.0
4.275IleSer: 4.275 ± 0.0
3.42IleThr: 3.42 ± 0.0
4.275IleVal: 4.275 ± 0.0
0.0IleTrp: 0.0 ± 0.0
2.138IleTyr: 2.138 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.703LysAla: 4.703 ± 0.0
1.283LysCys: 1.283 ± 0.0
5.985LysAsp: 5.985 ± 0.0
5.985LysGlu: 5.985 ± 0.0
4.703LysPhe: 4.703 ± 0.0
4.703LysGly: 4.703 ± 0.0
2.138LysHis: 2.138 ± 0.0
4.703LysIle: 4.703 ± 0.0
5.13LysLys: 5.13 ± 0.0
7.696LysLeu: 7.696 ± 0.0
1.71LysMet: 1.71 ± 0.0
5.985LysAsn: 5.985 ± 0.0
2.138LysPro: 2.138 ± 0.0
2.138LysGln: 2.138 ± 0.0
5.13LysArg: 5.13 ± 0.0
5.985LysSer: 5.985 ± 0.0
5.13LysThr: 5.13 ± 0.0
5.558LysVal: 5.558 ± 0.0
0.0LysTrp: 0.0 ± 0.0
5.985LysTyr: 5.985 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
2.565LeuAla: 2.565 ± 0.0
0.855LeuCys: 0.855 ± 0.0
5.13LeuAsp: 5.13 ± 0.0
8.551LeuGlu: 8.551 ± 0.0
3.42LeuPhe: 3.42 ± 0.0
3.848LeuGly: 3.848 ± 0.0
2.565LeuHis: 2.565 ± 0.0
5.13LeuIle: 5.13 ± 0.0
9.833LeuLys: 9.833 ± 0.0
6.413LeuLeu: 6.413 ± 0.0
2.138LeuMet: 2.138 ± 0.0
5.13LeuAsn: 5.13 ± 0.0
0.0LeuPro: 0.0 ± 0.0
2.565LeuGln: 2.565 ± 0.0
3.848LeuArg: 3.848 ± 0.0
3.848LeuSer: 3.848 ± 0.0
6.413LeuThr: 6.413 ± 0.0
6.841LeuVal: 6.841 ± 0.0
0.855LeuTrp: 0.855 ± 0.0
1.283LeuTyr: 1.283 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.283MetAla: 1.283 ± 0.0
0.428MetCys: 0.428 ± 0.0
1.283MetAsp: 1.283 ± 0.0
2.138MetGlu: 2.138 ± 0.0
0.855MetPhe: 0.855 ± 0.0
0.428MetGly: 0.428 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.855MetIle: 0.855 ± 0.0
2.138MetLys: 2.138 ± 0.0
2.138MetLeu: 2.138 ± 0.0
0.855MetMet: 0.855 ± 0.0
2.565MetAsn: 2.565 ± 0.0
0.855MetPro: 0.855 ± 0.0
0.855MetGln: 0.855 ± 0.0
2.138MetArg: 2.138 ± 0.0
2.993MetSer: 2.993 ± 0.0
0.855MetThr: 0.855 ± 0.0
1.71MetVal: 1.71 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.71MetTyr: 1.71 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.275AsnAla: 4.275 ± 0.0
1.283AsnCys: 1.283 ± 0.0
3.848AsnAsp: 3.848 ± 0.0
5.558AsnGlu: 5.558 ± 0.0
4.275AsnPhe: 4.275 ± 0.0
2.565AsnGly: 2.565 ± 0.0
3.42AsnHis: 3.42 ± 0.0
5.558AsnIle: 5.558 ± 0.0
5.558AsnLys: 5.558 ± 0.0
5.13AsnLeu: 5.13 ± 0.0
3.42AsnMet: 3.42 ± 0.0
4.703AsnAsn: 4.703 ± 0.0
1.71AsnPro: 1.71 ± 0.0
0.855AsnGln: 0.855 ± 0.0
4.703AsnArg: 4.703 ± 0.0
2.993AsnSer: 2.993 ± 0.0
6.413AsnThr: 6.413 ± 0.0
5.558AsnVal: 5.558 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
2.993AsnTyr: 2.993 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.71ProAla: 1.71 ± 0.0
0.0ProCys: 0.0 ± 0.0
0.855ProAsp: 0.855 ± 0.0
1.283ProGlu: 1.283 ± 0.0
0.855ProPhe: 0.855 ± 0.0
2.565ProGly: 2.565 ± 0.0
0.0ProHis: 0.0 ± 0.0
2.993ProIle: 2.993 ± 0.0
0.855ProLys: 0.855 ± 0.0
1.71ProLeu: 1.71 ± 0.0
0.428ProMet: 0.428 ± 0.0
0.855ProAsn: 0.855 ± 0.0
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
0.428ProArg: 0.428 ± 0.0
1.283ProSer: 1.283 ± 0.0
1.283ProThr: 1.283 ± 0.0
0.855ProVal: 0.855 ± 0.0
0.428ProTrp: 0.428 ± 0.0
0.428ProTyr: 0.428 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.565GlnAla: 2.565 ± 0.0
0.855GlnCys: 0.855 ± 0.0
1.283GlnAsp: 1.283 ± 0.0
0.855GlnGlu: 0.855 ± 0.0
1.283GlnPhe: 1.283 ± 0.0
0.855GlnGly: 0.855 ± 0.0
0.428GlnHis: 0.428 ± 0.0
0.855GlnIle: 0.855 ± 0.0
0.855GlnLys: 0.855 ± 0.0
1.71GlnLeu: 1.71 ± 0.0
0.0GlnMet: 0.0 ± 0.0
1.71GlnAsn: 1.71 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.855GlnGln: 0.855 ± 0.0
1.71GlnArg: 1.71 ± 0.0
2.138GlnSer: 2.138 ± 0.0
0.855GlnThr: 0.855 ± 0.0
2.565GlnVal: 2.565 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.283GlnTyr: 1.283 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.138ArgAla: 2.138 ± 0.0
1.71ArgCys: 1.71 ± 0.0
0.855ArgAsp: 0.855 ± 0.0
2.993ArgGlu: 2.993 ± 0.0
4.275ArgPhe: 4.275 ± 0.0
0.855ArgGly: 0.855 ± 0.0
1.71ArgHis: 1.71 ± 0.0
3.42ArgIle: 3.42 ± 0.0
5.13ArgLys: 5.13 ± 0.0
4.703ArgLeu: 4.703 ± 0.0
1.71ArgMet: 1.71 ± 0.0
2.993ArgAsn: 2.993 ± 0.0
1.283ArgPro: 1.283 ± 0.0
2.138ArgGln: 2.138 ± 0.0
2.565ArgArg: 2.565 ± 0.0
4.703ArgSer: 4.703 ± 0.0
2.993ArgThr: 2.993 ± 0.0
5.13ArgVal: 5.13 ± 0.0
0.428ArgTrp: 0.428 ± 0.0
4.275ArgTyr: 4.275 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.565SerAla: 2.565 ± 0.0
0.0SerCys: 0.0 ± 0.0
4.275SerAsp: 4.275 ± 0.0
4.703SerGlu: 4.703 ± 0.0
2.138SerPhe: 2.138 ± 0.0
3.848SerGly: 3.848 ± 0.0
0.428SerHis: 0.428 ± 0.0
2.993SerIle: 2.993 ± 0.0
5.985SerLys: 5.985 ± 0.0
4.703SerLeu: 4.703 ± 0.0
2.138SerMet: 2.138 ± 0.0
2.993SerAsn: 2.993 ± 0.0
0.855SerPro: 0.855 ± 0.0
1.283SerGln: 1.283 ± 0.0
5.558SerArg: 5.558 ± 0.0
2.993SerSer: 2.993 ± 0.0
4.275SerThr: 4.275 ± 0.0
3.848SerVal: 3.848 ± 0.0
0.0SerTrp: 0.0 ± 0.0
2.138SerTyr: 2.138 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.138ThrAla: 2.138 ± 0.0
1.283ThrCys: 1.283 ± 0.0
2.138ThrAsp: 2.138 ± 0.0
5.13ThrGlu: 5.13 ± 0.0
2.993ThrPhe: 2.993 ± 0.0
0.855ThrGly: 0.855 ± 0.0
1.283ThrHis: 1.283 ± 0.0
2.565ThrIle: 2.565 ± 0.0
5.13ThrLys: 5.13 ± 0.0
6.841ThrLeu: 6.841 ± 0.0
0.0ThrMet: 0.0 ± 0.0
4.703ThrAsn: 4.703 ± 0.0
1.283ThrPro: 1.283 ± 0.0
2.138ThrGln: 2.138 ± 0.0
3.848ThrArg: 3.848 ± 0.0
1.283ThrSer: 1.283 ± 0.0
2.565ThrThr: 2.565 ± 0.0
5.985ThrVal: 5.985 ± 0.0
0.428ThrTrp: 0.428 ± 0.0
2.565ThrTyr: 2.565 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.848ValAla: 3.848 ± 0.0
1.283ValCys: 1.283 ± 0.0
4.275ValAsp: 4.275 ± 0.0
3.848ValGlu: 3.848 ± 0.0
2.138ValPhe: 2.138 ± 0.0
5.985ValGly: 5.985 ± 0.0
1.283ValHis: 1.283 ± 0.0
3.848ValIle: 3.848 ± 0.0
8.978ValLys: 8.978 ± 0.0
4.275ValLeu: 4.275 ± 0.0
0.855ValMet: 0.855 ± 0.0
4.275ValAsn: 4.275 ± 0.0
3.42ValPro: 3.42 ± 0.0
1.71ValGln: 1.71 ± 0.0
3.848ValArg: 3.848 ± 0.0
5.13ValSer: 5.13 ± 0.0
1.71ValThr: 1.71 ± 0.0
6.413ValVal: 6.413 ± 0.0
0.855ValTrp: 0.855 ± 0.0
4.703ValTyr: 4.703 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.428TrpAla: 0.428 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.428TrpAsp: 0.428 ± 0.0
0.855TrpGlu: 0.855 ± 0.0
0.428TrpPhe: 0.428 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.428TrpIle: 0.428 ± 0.0
0.428TrpLys: 0.428 ± 0.0
0.428TrpLeu: 0.428 ± 0.0
0.428TrpMet: 0.428 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.428TrpArg: 0.428 ± 0.0
0.428TrpSer: 0.428 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.855TrpTyr: 0.855 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.993TyrAla: 2.993 ± 0.0
0.428TyrCys: 0.428 ± 0.0
5.985TyrAsp: 5.985 ± 0.0
3.42TyrGlu: 3.42 ± 0.0
2.993TyrPhe: 2.993 ± 0.0
2.565TyrGly: 2.565 ± 0.0
0.855TyrHis: 0.855 ± 0.0
4.703TyrIle: 4.703 ± 0.0
1.71TyrLys: 1.71 ± 0.0
2.138TyrLeu: 2.138 ± 0.0
0.855TyrMet: 0.855 ± 0.0
4.275TyrAsn: 4.275 ± 0.0
0.0TyrPro: 0.0 ± 0.0
1.283TyrGln: 1.283 ± 0.0
2.993TyrArg: 2.993 ± 0.0
0.428TyrSer: 0.428 ± 0.0
2.565TyrThr: 2.565 ± 0.0
2.993TyrVal: 2.993 ± 0.0
0.428TyrTrp: 0.428 ± 0.0
4.275TyrTyr: 4.275 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2340 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski