Amino acid dipepetide frequency for Diabrotica virgifera virgifera virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.973AlaAla: 2.973 ± 0.0
0.661AlaCys: 0.661 ± 0.0
4.955AlaAsp: 4.955 ± 0.0
4.295AlaGlu: 4.295 ± 0.0
3.304AlaPhe: 3.304 ± 0.0
3.634AlaGly: 3.634 ± 0.0
1.321AlaHis: 1.321 ± 0.0
4.625AlaIle: 4.625 ± 0.0
2.313AlaLys: 2.313 ± 0.0
5.616AlaLeu: 5.616 ± 0.0
2.313AlaMet: 2.313 ± 0.0
3.304AlaAsn: 3.304 ± 0.0
1.982AlaPro: 1.982 ± 0.0
4.625AlaGln: 4.625 ± 0.0
1.982AlaArg: 1.982 ± 0.0
3.634AlaSer: 3.634 ± 0.0
6.277AlaThr: 6.277 ± 0.0
4.295AlaVal: 4.295 ± 0.0
0.661AlaTrp: 0.661 ± 0.0
3.964AlaTyr: 3.964 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.991CysAla: 0.991 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.661CysAsp: 0.661 ± 0.0
0.33CysGlu: 0.33 ± 0.0
0.661CysPhe: 0.661 ± 0.0
1.982CysGly: 1.982 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.991CysIle: 0.991 ± 0.0
0.661CysLys: 0.661 ± 0.0
1.321CysLeu: 1.321 ± 0.0
0.33CysMet: 0.33 ± 0.0
1.321CysAsn: 1.321 ± 0.0
1.652CysPro: 1.652 ± 0.0
0.991CysGln: 0.991 ± 0.0
2.643CysArg: 2.643 ± 0.0
1.321CysSer: 1.321 ± 0.0
0.991CysThr: 0.991 ± 0.0
0.991CysVal: 0.991 ± 0.0
0.33CysTrp: 0.33 ± 0.0
1.321CysTyr: 1.321 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.277AspAla: 6.277 ± 0.0
0.991AspCys: 0.991 ± 0.0
5.286AspAsp: 5.286 ± 0.0
4.625AspGlu: 4.625 ± 0.0
4.955AspPhe: 4.955 ± 0.0
2.313AspGly: 2.313 ± 0.0
0.991AspHis: 0.991 ± 0.0
2.643AspIle: 2.643 ± 0.0
2.973AspLys: 2.973 ± 0.0
4.955AspLeu: 4.955 ± 0.0
1.982AspMet: 1.982 ± 0.0
1.982AspAsn: 1.982 ± 0.0
2.643AspPro: 2.643 ± 0.0
1.652AspGln: 1.652 ± 0.0
2.313AspArg: 2.313 ± 0.0
3.634AspSer: 3.634 ± 0.0
1.982AspThr: 1.982 ± 0.0
3.964AspVal: 3.964 ± 0.0
0.991AspTrp: 0.991 ± 0.0
1.321AspTyr: 1.321 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.304GluAla: 3.304 ± 0.0
2.313GluCys: 2.313 ± 0.0
2.973GluAsp: 2.973 ± 0.0
5.616GluGlu: 5.616 ± 0.0
1.982GluPhe: 1.982 ± 0.0
1.652GluGly: 1.652 ± 0.0
1.652GluHis: 1.652 ± 0.0
3.634GluIle: 3.634 ± 0.0
4.625GluLys: 4.625 ± 0.0
2.973GluLeu: 2.973 ± 0.0
0.661GluMet: 0.661 ± 0.0
0.661GluAsn: 0.661 ± 0.0
1.652GluPro: 1.652 ± 0.0
4.295GluGln: 4.295 ± 0.0
5.286GluArg: 5.286 ± 0.0
2.313GluSer: 2.313 ± 0.0
5.946GluThr: 5.946 ± 0.0
4.625GluVal: 4.625 ± 0.0
0.991GluTrp: 0.991 ± 0.0
3.304GluTyr: 3.304 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.982PheAla: 1.982 ± 0.0
0.991PheCys: 0.991 ± 0.0
2.973PheAsp: 2.973 ± 0.0
1.321PheGlu: 1.321 ± 0.0
1.321PhePhe: 1.321 ± 0.0
2.643PheGly: 2.643 ± 0.0
0.991PheHis: 0.991 ± 0.0
1.652PheIle: 1.652 ± 0.0
4.295PheLys: 4.295 ± 0.0
3.634PheLeu: 3.634 ± 0.0
1.652PheMet: 1.652 ± 0.0
2.313PheAsn: 2.313 ± 0.0
2.313PhePro: 2.313 ± 0.0
0.33PheGln: 0.33 ± 0.0
1.321PheArg: 1.321 ± 0.0
3.304PheSer: 3.304 ± 0.0
3.964PheThr: 3.964 ± 0.0
2.313PheVal: 2.313 ± 0.0
0.991PheTrp: 0.991 ± 0.0
1.652PheTyr: 1.652 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.304GlyAla: 3.304 ± 0.0
0.991GlyCys: 0.991 ± 0.0
2.643GlyAsp: 2.643 ± 0.0
1.982GlyGlu: 1.982 ± 0.0
1.982GlyPhe: 1.982 ± 0.0
2.643GlyGly: 2.643 ± 0.0
1.321GlyHis: 1.321 ± 0.0
2.643GlyIle: 2.643 ± 0.0
3.964GlyLys: 3.964 ± 0.0
3.964GlyLeu: 3.964 ± 0.0
0.991GlyMet: 0.991 ± 0.0
2.643GlyAsn: 2.643 ± 0.0
3.964GlyPro: 3.964 ± 0.0
2.313GlyGln: 2.313 ± 0.0
2.643GlyArg: 2.643 ± 0.0
3.304GlySer: 3.304 ± 0.0
5.286GlyThr: 5.286 ± 0.0
3.304GlyVal: 3.304 ± 0.0
0.991GlyTrp: 0.991 ± 0.0
3.634GlyTyr: 3.634 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.991HisAla: 0.991 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.991HisAsp: 0.991 ± 0.0
0.661HisGlu: 0.661 ± 0.0
0.661HisPhe: 0.661 ± 0.0
1.652HisGly: 1.652 ± 0.0
0.33HisHis: 0.33 ± 0.0
2.313HisIle: 2.313 ± 0.0
0.33HisLys: 0.33 ± 0.0
2.973HisLeu: 2.973 ± 0.0
0.661HisMet: 0.661 ± 0.0
1.321HisAsn: 1.321 ± 0.0
0.33HisPro: 0.33 ± 0.0
0.991HisGln: 0.991 ± 0.0
1.321HisArg: 1.321 ± 0.0
0.661HisSer: 0.661 ± 0.0
1.652HisThr: 1.652 ± 0.0
1.321HisVal: 1.321 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.33HisTyr: 0.33 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.643IleAla: 2.643 ± 0.0
0.991IleCys: 0.991 ± 0.0
3.304IleAsp: 3.304 ± 0.0
3.304IleGlu: 3.304 ± 0.0
2.643IlePhe: 2.643 ± 0.0
4.625IleGly: 4.625 ± 0.0
0.991IleHis: 0.991 ± 0.0
4.295IleIle: 4.295 ± 0.0
3.304IleLys: 3.304 ± 0.0
5.616IleLeu: 5.616 ± 0.0
1.982IleMet: 1.982 ± 0.0
3.634IleAsn: 3.634 ± 0.0
4.625IlePro: 4.625 ± 0.0
2.643IleGln: 2.643 ± 0.0
4.295IleArg: 4.295 ± 0.0
5.946IleSer: 5.946 ± 0.0
3.634IleThr: 3.634 ± 0.0
3.964IleVal: 3.964 ± 0.0
0.991IleTrp: 0.991 ± 0.0
1.982IleTyr: 1.982 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.313LysAla: 2.313 ± 0.0
0.991LysCys: 0.991 ± 0.0
2.973LysAsp: 2.973 ± 0.0
5.616LysGlu: 5.616 ± 0.0
1.652LysPhe: 1.652 ± 0.0
0.661LysGly: 0.661 ± 0.0
0.661LysHis: 0.661 ± 0.0
2.643LysIle: 2.643 ± 0.0
2.313LysLys: 2.313 ± 0.0
5.616LysLeu: 5.616 ± 0.0
1.652LysMet: 1.652 ± 0.0
1.982LysAsn: 1.982 ± 0.0
2.973LysPro: 2.973 ± 0.0
1.982LysGln: 1.982 ± 0.0
3.964LysArg: 3.964 ± 0.0
3.964LysSer: 3.964 ± 0.0
4.625LysThr: 4.625 ± 0.0
4.625LysVal: 4.625 ± 0.0
0.33LysTrp: 0.33 ± 0.0
2.973LysTyr: 2.973 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
7.268LeuAla: 7.268 ± 0.0
0.991LeuCys: 0.991 ± 0.0
4.625LeuAsp: 4.625 ± 0.0
4.295LeuGlu: 4.295 ± 0.0
2.313LeuPhe: 2.313 ± 0.0
4.295LeuGly: 4.295 ± 0.0
0.661LeuHis: 0.661 ± 0.0
3.634LeuIle: 3.634 ± 0.0
5.286LeuLys: 5.286 ± 0.0
5.946LeuLeu: 5.946 ± 0.0
0.991LeuMet: 0.991 ± 0.0
3.964LeuAsn: 3.964 ± 0.0
5.616LeuPro: 5.616 ± 0.0
4.955LeuGln: 4.955 ± 0.0
4.295LeuArg: 4.295 ± 0.0
4.295LeuSer: 4.295 ± 0.0
9.25LeuThr: 9.25 ± 0.0
3.964LeuVal: 3.964 ± 0.0
0.661LeuTrp: 0.661 ± 0.0
2.973LeuTyr: 2.973 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.661MetAla: 0.661 ± 0.0
0.661MetCys: 0.661 ± 0.0
2.313MetAsp: 2.313 ± 0.0
1.652MetGlu: 1.652 ± 0.0
2.643MetPhe: 2.643 ± 0.0
0.991MetGly: 0.991 ± 0.0
1.652MetHis: 1.652 ± 0.0
1.982MetIle: 1.982 ± 0.0
1.652MetLys: 1.652 ± 0.0
2.973MetLeu: 2.973 ± 0.0
0.33MetMet: 0.33 ± 0.0
0.661MetAsn: 0.661 ± 0.0
0.661MetPro: 0.661 ± 0.0
0.661MetGln: 0.661 ± 0.0
1.652MetArg: 1.652 ± 0.0
1.982MetSer: 1.982 ± 0.0
1.982MetThr: 1.982 ± 0.0
2.313MetVal: 2.313 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.33MetTyr: 0.33 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.982AsnAla: 1.982 ± 0.0
1.652AsnCys: 1.652 ± 0.0
2.643AsnAsp: 2.643 ± 0.0
1.982AsnGlu: 1.982 ± 0.0
0.33AsnPhe: 0.33 ± 0.0
1.982AsnGly: 1.982 ± 0.0
0.661AsnHis: 0.661 ± 0.0
6.607AsnIle: 6.607 ± 0.0
1.982AsnLys: 1.982 ± 0.0
4.295AsnLeu: 4.295 ± 0.0
0.991AsnMet: 0.991 ± 0.0
2.313AsnAsn: 2.313 ± 0.0
3.964AsnPro: 3.964 ± 0.0
1.982AsnGln: 1.982 ± 0.0
2.973AsnArg: 2.973 ± 0.0
3.304AsnSer: 3.304 ± 0.0
4.955AsnThr: 4.955 ± 0.0
1.321AsnVal: 1.321 ± 0.0
0.661AsnTrp: 0.661 ± 0.0
0.661AsnTyr: 0.661 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.634ProAla: 3.634 ± 0.0
0.661ProCys: 0.661 ± 0.0
2.313ProAsp: 2.313 ± 0.0
4.295ProGlu: 4.295 ± 0.0
2.973ProPhe: 2.973 ± 0.0
3.304ProGly: 3.304 ± 0.0
0.0ProHis: 0.0 ± 0.0
3.304ProIle: 3.304 ± 0.0
0.661ProLys: 0.661 ± 0.0
4.625ProLeu: 4.625 ± 0.0
1.321ProMet: 1.321 ± 0.0
1.982ProAsn: 1.982 ± 0.0
1.982ProPro: 1.982 ± 0.0
2.643ProGln: 2.643 ± 0.0
2.313ProArg: 2.313 ± 0.0
2.313ProSer: 2.313 ± 0.0
5.286ProThr: 5.286 ± 0.0
2.313ProVal: 2.313 ± 0.0
0.33ProTrp: 0.33 ± 0.0
1.982ProTyr: 1.982 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
5.286GlnAla: 5.286 ± 0.0
1.982GlnCys: 1.982 ± 0.0
1.982GlnAsp: 1.982 ± 0.0
1.982GlnGlu: 1.982 ± 0.0
1.982GlnPhe: 1.982 ± 0.0
3.304GlnGly: 3.304 ± 0.0
1.321GlnHis: 1.321 ± 0.0
1.652GlnIle: 1.652 ± 0.0
0.661GlnLys: 0.661 ± 0.0
3.634GlnLeu: 3.634 ± 0.0
2.313GlnMet: 2.313 ± 0.0
1.652GlnAsn: 1.652 ± 0.0
1.982GlnPro: 1.982 ± 0.0
2.643GlnGln: 2.643 ± 0.0
2.643GlnArg: 2.643 ± 0.0
2.313GlnSer: 2.313 ± 0.0
1.652GlnThr: 1.652 ± 0.0
2.313GlnVal: 2.313 ± 0.0
0.661GlnTrp: 0.661 ± 0.0
1.982GlnTyr: 1.982 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.304ArgAla: 3.304 ± 0.0
0.991ArgCys: 0.991 ± 0.0
4.295ArgAsp: 4.295 ± 0.0
1.982ArgGlu: 1.982 ± 0.0
1.982ArgPhe: 1.982 ± 0.0
3.634ArgGly: 3.634 ± 0.0
1.982ArgHis: 1.982 ± 0.0
3.634ArgIle: 3.634 ± 0.0
2.643ArgLys: 2.643 ± 0.0
4.955ArgLeu: 4.955 ± 0.0
1.321ArgMet: 1.321 ± 0.0
3.964ArgAsn: 3.964 ± 0.0
1.652ArgPro: 1.652 ± 0.0
2.313ArgGln: 2.313 ± 0.0
3.634ArgArg: 3.634 ± 0.0
1.321ArgSer: 1.321 ± 0.0
4.295ArgThr: 4.295 ± 0.0
2.973ArgVal: 2.973 ± 0.0
0.661ArgTrp: 0.661 ± 0.0
2.973ArgTyr: 2.973 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.616SerAla: 5.616 ± 0.0
1.652SerCys: 1.652 ± 0.0
2.313SerAsp: 2.313 ± 0.0
5.286SerGlu: 5.286 ± 0.0
2.643SerPhe: 2.643 ± 0.0
4.625SerGly: 4.625 ± 0.0
0.991SerHis: 0.991 ± 0.0
2.973SerIle: 2.973 ± 0.0
3.634SerLys: 3.634 ± 0.0
4.295SerLeu: 4.295 ± 0.0
2.643SerMet: 2.643 ± 0.0
2.313SerAsn: 2.313 ± 0.0
2.313SerPro: 2.313 ± 0.0
1.652SerGln: 1.652 ± 0.0
1.982SerArg: 1.982 ± 0.0
1.321SerSer: 1.321 ± 0.0
4.955SerThr: 4.955 ± 0.0
3.304SerVal: 3.304 ± 0.0
1.652SerTrp: 1.652 ± 0.0
2.973SerTyr: 2.973 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.286ThrAla: 5.286 ± 0.0
1.321ThrCys: 1.321 ± 0.0
3.634ThrAsp: 3.634 ± 0.0
3.964ThrGlu: 3.964 ± 0.0
3.304ThrPhe: 3.304 ± 0.0
3.964ThrGly: 3.964 ± 0.0
1.652ThrHis: 1.652 ± 0.0
9.25ThrIle: 9.25 ± 0.0
4.625ThrLys: 4.625 ± 0.0
4.625ThrLeu: 4.625 ± 0.0
0.661ThrMet: 0.661 ± 0.0
4.955ThrAsn: 4.955 ± 0.0
3.964ThrPro: 3.964 ± 0.0
4.625ThrGln: 4.625 ± 0.0
2.643ThrArg: 2.643 ± 0.0
4.955ThrSer: 4.955 ± 0.0
6.277ThrThr: 6.277 ± 0.0
6.277ThrVal: 6.277 ± 0.0
1.652ThrTrp: 1.652 ± 0.0
2.973ThrTyr: 2.973 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.616ValAla: 5.616 ± 0.0
0.991ValCys: 0.991 ± 0.0
3.634ValAsp: 3.634 ± 0.0
2.973ValGlu: 2.973 ± 0.0
2.973ValPhe: 2.973 ± 0.0
4.295ValGly: 4.295 ± 0.0
0.33ValHis: 0.33 ± 0.0
2.973ValIle: 2.973 ± 0.0
5.616ValLys: 5.616 ± 0.0
3.964ValLeu: 3.964 ± 0.0
2.313ValMet: 2.313 ± 0.0
2.643ValAsn: 2.643 ± 0.0
2.973ValPro: 2.973 ± 0.0
0.661ValGln: 0.661 ± 0.0
3.964ValArg: 3.964 ± 0.0
5.286ValSer: 5.286 ± 0.0
3.964ValThr: 3.964 ± 0.0
2.973ValVal: 2.973 ± 0.0
0.661ValTrp: 0.661 ± 0.0
1.652ValTyr: 1.652 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.661TrpAla: 0.661 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.33TrpAsp: 0.33 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.33TrpPhe: 0.33 ± 0.0
0.33TrpGly: 0.33 ± 0.0
0.661TrpHis: 0.661 ± 0.0
0.991TrpIle: 0.991 ± 0.0
1.321TrpLys: 1.321 ± 0.0
1.982TrpLeu: 1.982 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.321TrpAsn: 1.321 ± 0.0
0.661TrpPro: 0.661 ± 0.0
1.321TrpGln: 1.321 ± 0.0
0.33TrpArg: 0.33 ± 0.0
1.321TrpSer: 1.321 ± 0.0
1.321TrpThr: 1.321 ± 0.0
0.33TrpVal: 0.33 ± 0.0
0.33TrpTrp: 0.33 ± 0.0
1.321TrpTyr: 1.321 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.643TyrAla: 2.643 ± 0.0
0.661TyrCys: 0.661 ± 0.0
3.634TyrAsp: 3.634 ± 0.0
4.625TyrGlu: 4.625 ± 0.0
1.321TyrPhe: 1.321 ± 0.0
1.982TyrGly: 1.982 ± 0.0
1.321TyrHis: 1.321 ± 0.0
2.973TyrIle: 2.973 ± 0.0
1.652TyrLys: 1.652 ± 0.0
2.313TyrLeu: 2.313 ± 0.0
2.313TyrMet: 2.313 ± 0.0
2.313TyrAsn: 2.313 ± 0.0
0.33TyrPro: 0.33 ± 0.0
0.661TyrGln: 0.661 ± 0.0
2.313TyrArg: 2.313 ± 0.0
2.643TyrSer: 2.643 ± 0.0
2.313TyrThr: 2.313 ± 0.0
2.973TyrVal: 2.973 ± 0.0
1.321TyrTrp: 1.321 ± 0.0
1.652TyrTyr: 1.652 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3028 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski