Amino acid dipepetide frequency for Hubei picorna-like virus 60

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.255AlaAla: 4.255 ± 0.0
0.327AlaCys: 0.327 ± 0.0
4.583AlaAsp: 4.583 ± 0.0
0.655AlaGlu: 0.655 ± 0.0
3.601AlaPhe: 3.601 ± 0.0
4.91AlaGly: 4.91 ± 0.0
1.637AlaHis: 1.637 ± 0.0
4.255AlaIle: 4.255 ± 0.0
7.201AlaLys: 7.201 ± 0.0
8.511AlaLeu: 8.511 ± 0.0
1.637AlaMet: 1.637 ± 0.0
4.255AlaAsn: 4.255 ± 0.0
3.273AlaPro: 3.273 ± 0.0
2.946AlaGln: 2.946 ± 0.0
3.928AlaArg: 3.928 ± 0.0
6.219AlaSer: 6.219 ± 0.0
5.892AlaThr: 5.892 ± 0.0
3.928AlaVal: 3.928 ± 0.0
1.637AlaTrp: 1.637 ± 0.0
0.655AlaTyr: 0.655 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.309CysAla: 1.309 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.327CysAsp: 0.327 ± 0.0
0.655CysGlu: 0.655 ± 0.0
0.327CysPhe: 0.327 ± 0.0
0.982CysGly: 0.982 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.655CysIle: 0.655 ± 0.0
0.327CysLys: 0.327 ± 0.0
0.982CysLeu: 0.982 ± 0.0
0.327CysMet: 0.327 ± 0.0
0.655CysAsn: 0.655 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.655CysGln: 0.655 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.982CysSer: 0.982 ± 0.0
0.327CysThr: 0.327 ± 0.0
0.327CysVal: 0.327 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.982CysTyr: 0.982 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.583AspAla: 4.583 ± 0.0
1.309AspCys: 1.309 ± 0.0
4.583AspAsp: 4.583 ± 0.0
2.619AspGlu: 2.619 ± 0.0
4.255AspPhe: 4.255 ± 0.0
2.291AspGly: 2.291 ± 0.0
0.327AspHis: 0.327 ± 0.0
3.273AspIle: 3.273 ± 0.0
3.273AspLys: 3.273 ± 0.0
6.219AspLeu: 6.219 ± 0.0
3.601AspMet: 3.601 ± 0.0
1.964AspAsn: 1.964 ± 0.0
3.928AspPro: 3.928 ± 0.0
0.655AspGln: 0.655 ± 0.0
0.982AspArg: 0.982 ± 0.0
2.619AspSer: 2.619 ± 0.0
3.601AspThr: 3.601 ± 0.0
2.291AspVal: 2.291 ± 0.0
0.655AspTrp: 0.655 ± 0.0
1.964AspTyr: 1.964 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.273GluAla: 3.273 ± 0.0
0.655GluCys: 0.655 ± 0.0
4.255GluAsp: 4.255 ± 0.0
3.273GluGlu: 3.273 ± 0.0
1.637GluPhe: 1.637 ± 0.0
2.946GluGly: 2.946 ± 0.0
1.964GluHis: 1.964 ± 0.0
2.619GluIle: 2.619 ± 0.0
2.946GluLys: 2.946 ± 0.0
4.91GluLeu: 4.91 ± 0.0
1.309GluMet: 1.309 ± 0.0
2.291GluAsn: 2.291 ± 0.0
0.655GluPro: 0.655 ± 0.0
3.273GluGln: 3.273 ± 0.0
2.291GluArg: 2.291 ± 0.0
2.619GluSer: 2.619 ± 0.0
5.892GluThr: 5.892 ± 0.0
2.619GluVal: 2.619 ± 0.0
0.982GluTrp: 0.982 ± 0.0
0.655GluTyr: 0.655 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.946PheAla: 2.946 ± 0.0
0.655PheCys: 0.655 ± 0.0
3.601PheAsp: 3.601 ± 0.0
2.291PheGlu: 2.291 ± 0.0
2.946PhePhe: 2.946 ± 0.0
3.601PheGly: 3.601 ± 0.0
1.637PheHis: 1.637 ± 0.0
1.964PheIle: 1.964 ± 0.0
1.964PheLys: 1.964 ± 0.0
3.601PheLeu: 3.601 ± 0.0
0.982PheMet: 0.982 ± 0.0
3.601PheAsn: 3.601 ± 0.0
1.964PhePro: 1.964 ± 0.0
3.601PheGln: 3.601 ± 0.0
2.291PheArg: 2.291 ± 0.0
3.601PheSer: 3.601 ± 0.0
2.619PheThr: 2.619 ± 0.0
1.964PheVal: 1.964 ± 0.0
0.327PheTrp: 0.327 ± 0.0
1.637PheTyr: 1.637 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.601GlyAla: 3.601 ± 0.0
0.0GlyCys: 0.0 ± 0.0
2.946GlyAsp: 2.946 ± 0.0
1.964GlyGlu: 1.964 ± 0.0
4.255GlyPhe: 4.255 ± 0.0
3.928GlyGly: 3.928 ± 0.0
1.637GlyHis: 1.637 ± 0.0
4.255GlyIle: 4.255 ± 0.0
4.255GlyLys: 4.255 ± 0.0
3.601GlyLeu: 3.601 ± 0.0
1.637GlyMet: 1.637 ± 0.0
3.601GlyAsn: 3.601 ± 0.0
0.982GlyPro: 0.982 ± 0.0
3.601GlyGln: 3.601 ± 0.0
1.964GlyArg: 1.964 ± 0.0
2.619GlySer: 2.619 ± 0.0
2.619GlyThr: 2.619 ± 0.0
2.619GlyVal: 2.619 ± 0.0
0.327GlyTrp: 0.327 ± 0.0
3.273GlyTyr: 3.273 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.327HisAla: 0.327 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.982HisAsp: 0.982 ± 0.0
1.964HisGlu: 1.964 ± 0.0
0.982HisPhe: 0.982 ± 0.0
0.655HisGly: 0.655 ± 0.0
1.309HisHis: 1.309 ± 0.0
0.982HisIle: 0.982 ± 0.0
2.291HisLys: 2.291 ± 0.0
2.946HisLeu: 2.946 ± 0.0
0.982HisMet: 0.982 ± 0.0
1.309HisAsn: 1.309 ± 0.0
1.309HisPro: 1.309 ± 0.0
2.291HisGln: 2.291 ± 0.0
0.982HisArg: 0.982 ± 0.0
1.964HisSer: 1.964 ± 0.0
1.309HisThr: 1.309 ± 0.0
1.309HisVal: 1.309 ± 0.0
0.327HisTrp: 0.327 ± 0.0
2.619HisTyr: 2.619 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.892IleAla: 5.892 ± 0.0
0.327IleCys: 0.327 ± 0.0
4.255IleAsp: 4.255 ± 0.0
3.601IleGlu: 3.601 ± 0.0
1.637IlePhe: 1.637 ± 0.0
6.874IleGly: 6.874 ± 0.0
0.655IleHis: 0.655 ± 0.0
4.255IleIle: 4.255 ± 0.0
4.583IleLys: 4.583 ± 0.0
1.964IleLeu: 1.964 ± 0.0
1.309IleMet: 1.309 ± 0.0
5.237IleAsn: 5.237 ± 0.0
2.291IlePro: 2.291 ± 0.0
3.273IleGln: 3.273 ± 0.0
3.928IleArg: 3.928 ± 0.0
4.583IleSer: 4.583 ± 0.0
6.874IleThr: 6.874 ± 0.0
2.946IleVal: 2.946 ± 0.0
0.982IleTrp: 0.982 ± 0.0
2.619IleTyr: 2.619 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.928LysAla: 3.928 ± 0.0
0.982LysCys: 0.982 ± 0.0
3.928LysAsp: 3.928 ± 0.0
4.91LysGlu: 4.91 ± 0.0
2.291LysPhe: 2.291 ± 0.0
2.291LysGly: 2.291 ± 0.0
2.619LysHis: 2.619 ± 0.0
3.928LysIle: 3.928 ± 0.0
3.601LysLys: 3.601 ± 0.0
3.273LysLeu: 3.273 ± 0.0
1.637LysMet: 1.637 ± 0.0
0.982LysAsn: 0.982 ± 0.0
2.946LysPro: 2.946 ± 0.0
3.601LysGln: 3.601 ± 0.0
4.583LysArg: 4.583 ± 0.0
4.255LysSer: 4.255 ± 0.0
4.583LysThr: 4.583 ± 0.0
2.946LysVal: 2.946 ± 0.0
1.964LysTrp: 1.964 ± 0.0
3.601LysTyr: 3.601 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.219LeuAla: 6.219 ± 0.0
0.982LeuCys: 0.982 ± 0.0
4.91LeuAsp: 4.91 ± 0.0
2.946LeuGlu: 2.946 ± 0.0
4.91LeuPhe: 4.91 ± 0.0
3.601LeuGly: 3.601 ± 0.0
1.964LeuHis: 1.964 ± 0.0
6.219LeuIle: 6.219 ± 0.0
4.91LeuLys: 4.91 ± 0.0
6.547LeuLeu: 6.547 ± 0.0
1.637LeuMet: 1.637 ± 0.0
4.91LeuAsn: 4.91 ± 0.0
2.946LeuPro: 2.946 ± 0.0
4.91LeuGln: 4.91 ± 0.0
2.946LeuArg: 2.946 ± 0.0
4.583LeuSer: 4.583 ± 0.0
7.529LeuThr: 7.529 ± 0.0
2.946LeuVal: 2.946 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
2.291LeuTyr: 2.291 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.946MetAla: 2.946 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.309MetAsp: 1.309 ± 0.0
0.982MetGlu: 0.982 ± 0.0
0.982MetPhe: 0.982 ± 0.0
0.982MetGly: 0.982 ± 0.0
1.309MetHis: 1.309 ± 0.0
1.964MetIle: 1.964 ± 0.0
0.982MetLys: 0.982 ± 0.0
0.982MetLeu: 0.982 ± 0.0
0.655MetMet: 0.655 ± 0.0
1.309MetAsn: 1.309 ± 0.0
3.273MetPro: 3.273 ± 0.0
3.273MetGln: 3.273 ± 0.0
0.655MetArg: 0.655 ± 0.0
1.637MetSer: 1.637 ± 0.0
2.946MetThr: 2.946 ± 0.0
1.309MetVal: 1.309 ± 0.0
0.327MetTrp: 0.327 ± 0.0
0.327MetTyr: 0.327 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.91AsnAla: 4.91 ± 0.0
0.982AsnCys: 0.982 ± 0.0
1.964AsnAsp: 1.964 ± 0.0
2.946AsnGlu: 2.946 ± 0.0
1.637AsnPhe: 1.637 ± 0.0
1.964AsnGly: 1.964 ± 0.0
0.982AsnHis: 0.982 ± 0.0
5.565AsnIle: 5.565 ± 0.0
3.928AsnLys: 3.928 ± 0.0
2.946AsnLeu: 2.946 ± 0.0
1.637AsnMet: 1.637 ± 0.0
4.583AsnAsn: 4.583 ± 0.0
3.928AsnPro: 3.928 ± 0.0
3.273AsnGln: 3.273 ± 0.0
1.637AsnArg: 1.637 ± 0.0
5.237AsnSer: 5.237 ± 0.0
2.946AsnThr: 2.946 ± 0.0
3.601AsnVal: 3.601 ± 0.0
1.309AsnTrp: 1.309 ± 0.0
0.655AsnTyr: 0.655 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.291ProAla: 2.291 ± 0.0
1.309ProCys: 1.309 ± 0.0
2.619ProAsp: 2.619 ± 0.0
2.619ProGlu: 2.619 ± 0.0
1.637ProPhe: 1.637 ± 0.0
2.946ProGly: 2.946 ± 0.0
1.309ProHis: 1.309 ± 0.0
3.273ProIle: 3.273 ± 0.0
3.601ProLys: 3.601 ± 0.0
3.601ProLeu: 3.601 ± 0.0
0.655ProMet: 0.655 ± 0.0
1.637ProAsn: 1.637 ± 0.0
1.309ProPro: 1.309 ± 0.0
4.255ProGln: 4.255 ± 0.0
0.655ProArg: 0.655 ± 0.0
3.928ProSer: 3.928 ± 0.0
3.601ProThr: 3.601 ± 0.0
1.637ProVal: 1.637 ± 0.0
0.655ProTrp: 0.655 ± 0.0
1.309ProTyr: 1.309 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
5.237GlnAla: 5.237 ± 0.0
0.327GlnCys: 0.327 ± 0.0
2.619GlnAsp: 2.619 ± 0.0
4.91GlnGlu: 4.91 ± 0.0
3.928GlnPhe: 3.928 ± 0.0
2.946GlnGly: 2.946 ± 0.0
2.619GlnHis: 2.619 ± 0.0
2.619GlnIle: 2.619 ± 0.0
3.273GlnLys: 3.273 ± 0.0
3.273GlnLeu: 3.273 ± 0.0
0.982GlnMet: 0.982 ± 0.0
3.928GlnAsn: 3.928 ± 0.0
2.946GlnPro: 2.946 ± 0.0
1.964GlnGln: 1.964 ± 0.0
1.637GlnArg: 1.637 ± 0.0
3.273GlnSer: 3.273 ± 0.0
1.964GlnThr: 1.964 ± 0.0
2.946GlnVal: 2.946 ± 0.0
0.327GlnTrp: 0.327 ± 0.0
1.964GlnTyr: 1.964 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.619ArgAla: 2.619 ± 0.0
0.0ArgCys: 0.0 ± 0.0
2.291ArgAsp: 2.291 ± 0.0
3.601ArgGlu: 3.601 ± 0.0
1.964ArgPhe: 1.964 ± 0.0
2.946ArgGly: 2.946 ± 0.0
0.655ArgHis: 0.655 ± 0.0
2.946ArgIle: 2.946 ± 0.0
2.291ArgLys: 2.291 ± 0.0
2.946ArgLeu: 2.946 ± 0.0
1.309ArgMet: 1.309 ± 0.0
1.309ArgAsn: 1.309 ± 0.0
1.637ArgPro: 1.637 ± 0.0
1.964ArgGln: 1.964 ± 0.0
1.309ArgArg: 1.309 ± 0.0
2.291ArgSer: 2.291 ± 0.0
2.291ArgThr: 2.291 ± 0.0
2.946ArgVal: 2.946 ± 0.0
0.327ArgTrp: 0.327 ± 0.0
2.291ArgTyr: 2.291 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
7.856SerAla: 7.856 ± 0.0
0.655SerCys: 0.655 ± 0.0
3.273SerAsp: 3.273 ± 0.0
1.964SerGlu: 1.964 ± 0.0
2.946SerPhe: 2.946 ± 0.0
3.273SerGly: 3.273 ± 0.0
2.291SerHis: 2.291 ± 0.0
5.237SerIle: 5.237 ± 0.0
2.946SerLys: 2.946 ± 0.0
6.547SerLeu: 6.547 ± 0.0
2.291SerMet: 2.291 ± 0.0
4.255SerAsn: 4.255 ± 0.0
3.273SerPro: 3.273 ± 0.0
2.291SerGln: 2.291 ± 0.0
2.946SerArg: 2.946 ± 0.0
5.237SerSer: 5.237 ± 0.0
6.219SerThr: 6.219 ± 0.0
3.928SerVal: 3.928 ± 0.0
0.0SerTrp: 0.0 ± 0.0
3.273SerTyr: 3.273 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.255ThrAla: 4.255 ± 0.0
0.655ThrCys: 0.655 ± 0.0
3.928ThrAsp: 3.928 ± 0.0
4.255ThrGlu: 4.255 ± 0.0
2.291ThrPhe: 2.291 ± 0.0
2.946ThrGly: 2.946 ± 0.0
2.946ThrHis: 2.946 ± 0.0
6.219ThrIle: 6.219 ± 0.0
3.601ThrLys: 3.601 ± 0.0
7.529ThrLeu: 7.529 ± 0.0
2.619ThrMet: 2.619 ± 0.0
3.928ThrAsn: 3.928 ± 0.0
3.928ThrPro: 3.928 ± 0.0
2.946ThrGln: 2.946 ± 0.0
2.291ThrArg: 2.291 ± 0.0
6.547ThrSer: 6.547 ± 0.0
4.583ThrThr: 4.583 ± 0.0
5.565ThrVal: 5.565 ± 0.0
0.655ThrTrp: 0.655 ± 0.0
3.601ThrTyr: 3.601 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.583ValAla: 4.583 ± 0.0
0.655ValCys: 0.655 ± 0.0
1.637ValAsp: 1.637 ± 0.0
2.946ValGlu: 2.946 ± 0.0
2.619ValPhe: 2.619 ± 0.0
1.637ValGly: 1.637 ± 0.0
0.327ValHis: 0.327 ± 0.0
4.255ValIle: 4.255 ± 0.0
3.601ValLys: 3.601 ± 0.0
4.255ValLeu: 4.255 ± 0.0
1.964ValMet: 1.964 ± 0.0
2.291ValAsn: 2.291 ± 0.0
1.637ValPro: 1.637 ± 0.0
2.291ValGln: 2.291 ± 0.0
2.291ValArg: 2.291 ± 0.0
5.565ValSer: 5.565 ± 0.0
4.255ValThr: 4.255 ± 0.0
3.273ValVal: 3.273 ± 0.0
0.327ValTrp: 0.327 ± 0.0
2.946ValTyr: 2.946 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.309TrpAla: 1.309 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.327TrpAsp: 0.327 ± 0.0
0.982TrpGlu: 0.982 ± 0.0
0.327TrpPhe: 0.327 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.964TrpIle: 1.964 ± 0.0
0.327TrpLys: 0.327 ± 0.0
0.982TrpLeu: 0.982 ± 0.0
0.327TrpMet: 0.327 ± 0.0
1.637TrpAsn: 1.637 ± 0.0
0.327TrpPro: 0.327 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.327TrpArg: 0.327 ± 0.0
0.327TrpSer: 0.327 ± 0.0
0.327TrpThr: 0.327 ± 0.0
1.309TrpVal: 1.309 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.327TrpTyr: 0.327 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.291TyrAla: 2.291 ± 0.0
0.0TyrCys: 0.0 ± 0.0
0.655TyrAsp: 0.655 ± 0.0
0.982TyrGlu: 0.982 ± 0.0
2.619TyrPhe: 2.619 ± 0.0
1.964TyrGly: 1.964 ± 0.0
0.655TyrHis: 0.655 ± 0.0
1.637TyrIle: 1.637 ± 0.0
2.946TyrLys: 2.946 ± 0.0
2.291TyrLeu: 2.291 ± 0.0
0.327TyrMet: 0.327 ± 0.0
2.946TyrAsn: 2.946 ± 0.0
2.291TyrPro: 2.291 ± 0.0
2.619TyrGln: 2.619 ± 0.0
2.291TyrArg: 2.291 ± 0.0
2.619TyrSer: 2.619 ± 0.0
4.91TyrThr: 4.91 ± 0.0
2.946TyrVal: 2.946 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
1.964TyrTyr: 1.964 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3056 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski