Amino acid dipepetide frequency for Hubei myriapoda virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.42AlaAla: 3.42 ± 1.323
0.0AlaCys: 0.0 ± 0.0
2.28AlaAsp: 2.28 ± 1.805
1.425AlaGlu: 1.425 ± 0.625
3.135AlaPhe: 3.135 ± 1.106
2.28AlaGly: 2.28 ± 0.838
0.57AlaHis: 0.57 ± 0.956
3.705AlaIle: 3.705 ± 2.151
4.845AlaLys: 4.845 ± 1.564
6.84AlaLeu: 6.84 ± 0.558
1.71AlaMet: 1.71 ± 0.649
1.425AlaAsn: 1.425 ± 0.97
2.28AlaPro: 2.28 ± 1.607
0.855AlaGln: 0.855 ± 0.323
1.71AlaArg: 1.71 ± 0.504
3.99AlaSer: 3.99 ± 1.196
4.275AlaThr: 4.275 ± 0.753
3.705AlaVal: 3.705 ± 1.349
0.285AlaTrp: 0.285 ± 0.158
1.425AlaTyr: 1.425 ± 1.409
0.0AlaXaa: 0.0 ± 0.0
Cys
0.855CysAla: 0.855 ± 0.323
0.285CysCys: 0.285 ± 0.158
0.57CysAsp: 0.57 ± 0.437
1.71CysGlu: 1.71 ± 0.645
1.14CysPhe: 1.14 ± 0.633
1.425CysGly: 1.425 ± 0.791
0.0CysHis: 0.0 ± 0.0
0.855CysIle: 0.855 ± 0.323
1.71CysLys: 1.71 ± 0.645
0.57CysLeu: 0.57 ± 0.316
0.285CysMet: 0.285 ± 0.158
0.855CysAsn: 0.855 ± 0.323
0.285CysPro: 0.285 ± 0.158
0.0CysGln: 0.0 ± 0.0
0.855CysArg: 0.855 ± 0.323
1.995CysSer: 1.995 ± 0.773
1.14CysThr: 1.14 ± 0.63
0.285CysVal: 0.285 ± 0.51
0.0CysTrp: 0.0 ± 0.0
0.285CysTyr: 0.285 ± 0.158
0.0CysXaa: 0.0 ± 0.0
Asp
2.85AspAla: 2.85 ± 0.903
1.995AspCys: 1.995 ± 0.773
2.85AspAsp: 2.85 ± 1.243
3.42AspGlu: 3.42 ± 0.152
4.845AspPhe: 4.845 ± 1.393
2.565AspGly: 2.565 ± 1.09
0.57AspHis: 0.57 ± 0.956
3.705AspIle: 3.705 ± 1.214
5.7AspLys: 5.7 ± 1.399
7.694AspLeu: 7.694 ± 1.996
1.425AspMet: 1.425 ± 0.353
2.565AspAsn: 2.565 ± 0.686
3.135AspPro: 3.135 ± 0.708
3.42AspGln: 3.42 ± 1.071
2.28AspArg: 2.28 ± 1.059
2.85AspSer: 2.85 ± 0.59
3.99AspThr: 3.99 ± 0.816
3.135AspVal: 3.135 ± 0.063
0.855AspTrp: 0.855 ± 0.323
3.135AspTyr: 3.135 ± 1.552
0.0AspXaa: 0.0 ± 0.0
Glu
1.425GluAla: 1.425 ± 0.515
0.57GluCys: 0.57 ± 0.316
4.845GluAsp: 4.845 ± 1.332
3.99GluGlu: 3.99 ± 0.789
3.42GluPhe: 3.42 ± 1.332
2.28GluGly: 2.28 ± 0.556
1.995GluHis: 1.995 ± 0.912
3.705GluIle: 3.705 ± 1.637
4.275GluLys: 4.275 ± 0.843
5.7GluLeu: 5.7 ± 1.388
1.71GluMet: 1.71 ± 0.303
4.275GluAsn: 4.275 ± 1.099
1.425GluPro: 1.425 ± 0.665
2.85GluGln: 2.85 ± 0.826
1.995GluArg: 1.995 ± 0.378
4.845GluSer: 4.845 ± 1.492
3.135GluThr: 3.135 ± 0.997
2.85GluVal: 2.85 ± 0.885
0.855GluTrp: 0.855 ± 0.475
1.425GluTyr: 1.425 ± 0.515
0.0GluXaa: 0.0 ± 0.0
Phe
1.425PheAla: 1.425 ± 0.791
0.855PheCys: 0.855 ± 0.323
3.42PheAsp: 3.42 ± 1.298
2.28PheGlu: 2.28 ± 0.497
3.42PhePhe: 3.42 ± 1.453
3.42PheGly: 3.42 ± 1.118
2.28PheHis: 2.28 ± 0.939
3.135PheIle: 3.135 ± 0.972
4.275PheLys: 4.275 ± 0.87
5.7PheLeu: 5.7 ± 0.772
0.855PheMet: 0.855 ± 0.606
2.85PheAsn: 2.85 ± 0.736
1.14PhePro: 1.14 ± 0.829
3.42PheGln: 3.42 ± 0.848
3.42PheArg: 3.42 ± 0.929
4.56PheSer: 4.56 ± 2.175
3.99PheThr: 3.99 ± 1.577
3.705PheVal: 3.705 ± 0.497
0.855PheTrp: 0.855 ± 0.323
1.995PheTyr: 1.995 ± 0.927
0.0PheXaa: 0.0 ± 0.0
Gly
2.85GlyAla: 2.85 ± 0.91
1.425GlyCys: 1.425 ± 0.353
2.565GlyAsp: 2.565 ± 0.599
1.14GlyGlu: 1.14 ± 0.441
3.135GlyPhe: 3.135 ± 0.786
2.28GlyGly: 2.28 ± 1.633
0.57GlyHis: 0.57 ± 0.316
5.13GlyIle: 5.13 ± 1.197
2.565GlyLys: 2.565 ± 0.362
3.42GlyLeu: 3.42 ± 1.628
1.14GlyMet: 1.14 ± 0.4
2.565GlyAsn: 2.565 ± 0.362
2.28GlyPro: 2.28 ± 0.882
1.995GlyGln: 1.995 ± 0.851
1.995GlyArg: 1.995 ± 1.06
2.565GlySer: 2.565 ± 1.138
3.135GlyThr: 3.135 ± 1.349
2.565GlyVal: 2.565 ± 0.761
0.57GlyTrp: 0.57 ± 0.315
1.425GlyTyr: 1.425 ± 0.515
0.0GlyXaa: 0.0 ± 0.0
His
0.855HisAla: 0.855 ± 0.323
0.285HisCys: 0.285 ± 0.158
1.71HisAsp: 1.71 ± 0.949
0.855HisGlu: 0.855 ± 0.475
1.425HisPhe: 1.425 ± 0.533
1.14HisGly: 1.14 ± 0.633
0.57HisHis: 0.57 ± 0.316
1.71HisIle: 1.71 ± 0.647
0.855HisLys: 0.855 ± 0.323
3.42HisLeu: 3.42 ± 0.836
0.285HisMet: 0.285 ± 0.158
1.14HisAsn: 1.14 ± 0.451
2.565HisPro: 2.565 ± 1.232
2.28HisGln: 2.28 ± 0.852
2.85HisArg: 2.85 ± 1.168
1.995HisSer: 1.995 ± 0.927
1.425HisThr: 1.425 ± 1.455
0.57HisVal: 0.57 ± 0.692
0.0HisTrp: 0.0 ± 0.0
1.425HisTyr: 1.425 ± 1.071
0.0HisXaa: 0.0 ± 0.0
Ile
5.13IleAla: 5.13 ± 1.949
0.57IleCys: 0.57 ± 0.316
5.415IleAsp: 5.415 ± 1.254
3.42IleGlu: 3.42 ± 1.163
4.275IlePhe: 4.275 ± 2.374
4.275IleGly: 4.275 ± 2.108
0.57IleHis: 0.57 ± 0.316
3.135IleIle: 3.135 ± 1.307
3.135IleLys: 3.135 ± 0.996
5.415IleLeu: 5.415 ± 1.866
1.71IleMet: 1.71 ± 0.666
3.705IleAsn: 3.705 ± 0.859
4.845IlePro: 4.845 ± 1.343
3.42IleGln: 3.42 ± 0.704
3.135IleArg: 3.135 ± 0.736
3.705IleSer: 3.705 ± 0.275
3.99IleThr: 3.99 ± 1.361
3.42IleVal: 3.42 ± 0.62
0.855IleTrp: 0.855 ± 0.323
4.275IleTyr: 4.275 ± 1.291
0.0IleXaa: 0.0 ± 0.0
Lys
2.85LysAla: 2.85 ± 0.713
0.855LysCys: 0.855 ± 0.475
4.275LysAsp: 4.275 ± 1.579
5.13LysGlu: 5.13 ± 1.127
3.705LysPhe: 3.705 ± 0.988
2.85LysGly: 2.85 ± 1.243
1.995LysHis: 1.995 ± 0.378
6.27LysIle: 6.27 ± 1.149
7.125LysLys: 7.125 ± 1.733
5.985LysLeu: 5.985 ± 0.614
1.14LysMet: 1.14 ± 0.4
5.415LysAsn: 5.415 ± 1.104
3.135LysPro: 3.135 ± 1.098
4.845LysGln: 4.845 ± 1.508
3.135LysArg: 3.135 ± 0.708
3.705LysSer: 3.705 ± 0.639
5.7LysThr: 5.7 ± 0.757
3.99LysVal: 3.99 ± 0.274
0.57LysTrp: 0.57 ± 0.315
3.99LysTyr: 3.99 ± 1.033
0.0LysXaa: 0.0 ± 0.0
Leu
7.125LeuAla: 7.125 ± 2.364
1.14LeuCys: 1.14 ± 0.633
6.27LeuAsp: 6.27 ± 1.347
5.985LeuGlu: 5.985 ± 2.051
5.7LeuPhe: 5.7 ± 1.652
2.85LeuGly: 2.85 ± 0.789
3.99LeuHis: 3.99 ± 0.46
6.27LeuIle: 6.27 ± 1.473
6.555LeuLys: 6.555 ± 1.524
9.689LeuLeu: 9.689 ± 1.381
1.425LeuMet: 1.425 ± 0.359
5.13LeuAsn: 5.13 ± 1.081
5.7LeuPro: 5.7 ± 2.455
5.415LeuGln: 5.415 ± 0.922
1.71LeuArg: 1.71 ± 0.645
5.415LeuSer: 5.415 ± 2.374
6.27LeuThr: 6.27 ± 1.844
5.415LeuVal: 5.415 ± 1.612
0.285LeuTrp: 0.285 ± 0.158
2.85LeuTyr: 2.85 ± 1.396
0.0LeuXaa: 0.0 ± 0.0
Met
0.855MetAla: 0.855 ± 0.558
0.0MetCys: 0.0 ± 0.0
1.14MetAsp: 1.14 ± 0.633
1.71MetGlu: 1.71 ± 0.949
0.57MetPhe: 0.57 ± 0.315
0.285MetGly: 0.285 ± 0.657
0.57MetHis: 0.57 ± 0.315
0.57MetIle: 0.57 ± 0.759
2.565MetLys: 2.565 ± 0.599
1.995MetLeu: 1.995 ± 0.444
0.285MetMet: 0.285 ± 0.38
1.71MetAsn: 1.71 ± 0.666
0.57MetPro: 0.57 ± 0.437
0.57MetGln: 0.57 ± 0.316
1.14MetArg: 1.14 ± 0.4
0.855MetSer: 0.855 ± 0.323
0.285MetThr: 0.285 ± 0.158
1.14MetVal: 1.14 ± 0.441
0.0MetTrp: 0.0 ± 0.0
2.28MetTyr: 2.28 ± 0.475
0.0MetXaa: 0.0 ± 0.0
Asn
1.71AsnAla: 1.71 ± 0.649
1.71AsnCys: 1.71 ± 0.578
3.705AsnAsp: 3.705 ± 0.988
2.28AsnGlu: 2.28 ± 0.377
3.135AsnPhe: 3.135 ± 0.67
3.705AsnGly: 3.705 ± 1.414
1.425AsnHis: 1.425 ± 1.071
3.99AsnIle: 3.99 ± 1.583
3.135AsnLys: 3.135 ± 0.476
6.84AsnLeu: 6.84 ± 0.608
1.71AsnMet: 1.71 ± 0.978
1.71AsnAsn: 1.71 ± 0.504
3.99AsnPro: 3.99 ± 1.111
3.705AsnGln: 3.705 ± 0.656
0.855AsnArg: 0.855 ± 0.535
5.415AsnSer: 5.415 ± 0.962
2.28AsnThr: 2.28 ± 0.715
2.565AsnVal: 2.565 ± 1.09
0.285AsnTrp: 0.285 ± 0.158
2.28AsnTyr: 2.28 ± 1.065
0.0AsnXaa: 0.0 ± 0.0
Pro
1.995ProAla: 1.995 ± 1.662
0.0ProCys: 0.0 ± 0.0
3.705ProAsp: 3.705 ± 1.848
5.415ProGlu: 5.415 ± 1.833
2.28ProPhe: 2.28 ± 0.718
2.565ProGly: 2.565 ± 1.5
1.14ProHis: 1.14 ± 0.451
1.995ProIle: 1.995 ± 0.71
5.7ProLys: 5.7 ± 1.3
4.56ProLeu: 4.56 ± 1.198
0.285ProMet: 0.285 ± 0.158
1.425ProAsn: 1.425 ± 0.584
2.85ProPro: 2.85 ± 1.667
2.28ProGln: 2.28 ± 0.838
1.995ProArg: 1.995 ± 0.912
3.705ProSer: 3.705 ± 2.698
4.56ProThr: 4.56 ± 1.108
1.71ProVal: 1.71 ± 1.721
1.14ProTrp: 1.14 ± 0.874
1.425ProTyr: 1.425 ± 0.356
0.0ProXaa: 0.0 ± 0.0
Gln
2.28GlnAla: 2.28 ± 0.882
0.57GlnCys: 0.57 ± 0.316
2.28GlnAsp: 2.28 ± 0.475
2.85GlnGlu: 2.85 ± 1.243
2.85GlnPhe: 2.85 ± 0.746
1.14GlnGly: 1.14 ± 0.633
1.995GlnHis: 1.995 ± 0.897
3.42GlnIle: 3.42 ± 0.699
3.705GlnLys: 3.705 ± 1.146
5.7GlnLeu: 5.7 ± 2.664
0.0GlnMet: 0.0 ± 0.0
4.845GlnAsn: 4.845 ± 1.42
2.28GlnPro: 2.28 ± 0.475
1.995GlnGln: 1.995 ± 0.378
2.28GlnArg: 2.28 ± 0.702
3.42GlnSer: 3.42 ± 0.857
3.99GlnThr: 3.99 ± 1.537
1.71GlnVal: 1.71 ± 0.645
0.57GlnTrp: 0.57 ± 0.315
1.71GlnTyr: 1.71 ± 0.331
0.0GlnXaa: 0.0 ± 0.0
Arg
1.425ArgAla: 1.425 ± 0.791
0.57ArgCys: 0.57 ± 0.315
4.56ArgAsp: 4.56 ± 1.206
2.28ArgGlu: 2.28 ± 0.894
1.995ArgPhe: 1.995 ± 0.525
1.14ArgGly: 1.14 ± 0.4
0.57ArgHis: 0.57 ± 0.316
2.85ArgIle: 2.85 ± 0.736
5.13ArgLys: 5.13 ± 1.637
2.85ArgLeu: 2.85 ± 0.826
1.14ArgMet: 1.14 ± 0.537
2.565ArgAsn: 2.565 ± 1.04
2.28ArgPro: 2.28 ± 0.377
2.565ArgGln: 2.565 ± 1.455
1.71ArgArg: 1.71 ± 0.649
1.14ArgSer: 1.14 ± 0.537
1.71ArgThr: 1.71 ± 0.578
1.71ArgVal: 1.71 ± 0.504
0.0ArgTrp: 0.0 ± 0.0
0.855ArgTyr: 0.855 ± 0.323
0.0ArgXaa: 0.0 ± 0.0
Ser
3.705SerAla: 3.705 ± 1.713
0.57SerCys: 0.57 ± 0.316
2.85SerAsp: 2.85 ± 0.885
4.275SerGlu: 4.275 ± 1.385
4.56SerPhe: 4.56 ± 1.666
4.275SerGly: 4.275 ± 2.095
2.565SerHis: 2.565 ± 0.636
8.549SerIle: 8.549 ± 1.226
5.7SerLys: 5.7 ± 1.806
5.7SerLeu: 5.7 ± 1.645
1.995SerMet: 1.995 ± 0.75
2.85SerAsn: 2.85 ± 0.454
3.135SerPro: 3.135 ± 1.708
2.565SerGln: 2.565 ± 1.537
1.71SerArg: 1.71 ± 0.666
5.7SerSer: 5.7 ± 0.578
3.42SerThr: 3.42 ± 0.686
1.71SerVal: 1.71 ± 0.936
1.14SerTrp: 1.14 ± 1.881
0.855SerTyr: 0.855 ± 0.323
0.0SerXaa: 0.0 ± 0.0
Thr
2.85ThrAla: 2.85 ± 1.575
1.71ThrCys: 1.71 ± 0.649
3.135ThrAsp: 3.135 ± 1.083
2.565ThrGlu: 2.565 ± 0.909
2.565ThrPhe: 2.565 ± 0.599
3.705ThrGly: 3.705 ± 1.05
2.28ThrHis: 2.28 ± 0.36
4.56ThrIle: 4.56 ± 0.67
4.845ThrLys: 4.845 ± 2.249
4.56ThrLeu: 4.56 ± 0.955
0.285ThrMet: 0.285 ± 0.158
3.42ThrAsn: 3.42 ± 1.901
3.135ThrPro: 3.135 ± 0.736
3.42ThrGln: 3.42 ± 0.686
1.995ThrArg: 1.995 ± 0.773
6.27ThrSer: 6.27 ± 3.615
4.845ThrThr: 4.845 ± 1.344
4.845ThrVal: 4.845 ± 1.622
0.855ThrTrp: 0.855 ± 0.323
3.99ThrTyr: 3.99 ± 1.175
0.0ThrXaa: 0.0 ± 0.0
Val
4.56ValAla: 4.56 ± 1.198
1.425ValCys: 1.425 ± 0.533
4.275ValAsp: 4.275 ± 0.353
2.85ValGlu: 2.85 ± 0.903
3.42ValPhe: 3.42 ± 1.274
1.14ValGly: 1.14 ± 0.63
0.285ValHis: 0.285 ± 0.158
2.28ValIle: 2.28 ± 0.939
1.71ValLys: 1.71 ± 0.666
4.845ValLeu: 4.845 ± 1.432
0.855ValMet: 0.855 ± 0.475
3.42ValAsn: 3.42 ± 0.932
3.705ValPro: 3.705 ± 1.853
2.28ValGln: 2.28 ± 0.377
1.995ValArg: 1.995 ± 0.378
2.85ValSer: 2.85 ± 2.067
3.135ValThr: 3.135 ± 0.878
1.995ValVal: 1.995 ± 0.408
0.285ValTrp: 0.285 ± 0.158
0.855ValTyr: 0.855 ± 0.415
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.57TrpAsp: 0.57 ± 0.692
1.14TrpGlu: 1.14 ± 0.63
0.57TrpPhe: 0.57 ± 0.437
0.285TrpGly: 0.285 ± 0.38
0.855TrpHis: 0.855 ± 0.535
0.855TrpIle: 0.855 ± 0.475
1.14TrpLys: 1.14 ± 0.451
0.57TrpLeu: 0.57 ± 0.316
0.0TrpMet: 0.0 ± 0.0
0.855TrpAsn: 0.855 ± 0.558
0.285TrpPro: 0.285 ± 0.38
0.0TrpGln: 0.0 ± 0.0
0.285TrpArg: 0.285 ± 0.158
0.57TrpSer: 0.57 ± 0.315
0.855TrpThr: 0.855 ± 0.475
0.855TrpVal: 0.855 ± 0.475
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.995TyrAla: 1.995 ± 0.994
0.57TyrCys: 0.57 ± 0.437
2.565TyrAsp: 2.565 ± 0.34
2.85TyrGlu: 2.85 ± 0.772
1.14TyrPhe: 1.14 ± 0.4
1.71TyrGly: 1.71 ± 0.978
2.565TyrHis: 2.565 ± 1.026
1.71TyrIle: 1.71 ± 0.368
1.995TyrLys: 1.995 ± 0.897
3.135TyrLeu: 3.135 ± 0.063
0.57TyrMet: 0.57 ± 0.315
3.705TyrAsn: 3.705 ± 0.692
1.71TyrPro: 1.71 ± 0.504
1.71TyrGln: 1.71 ± 1.471
1.995TyrArg: 1.995 ± 1.108
2.28TyrSer: 2.28 ± 0.995
3.705TyrThr: 3.705 ± 1.385
0.285TyrVal: 0.285 ± 0.158
0.285TyrTrp: 0.285 ± 0.158
1.425TyrTyr: 1.425 ± 0.837
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3510 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski