Amino acid dipepetide frequency for Fowl aviadenovirus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.554AlaAla: 7.554 ± 0.986
1.09AlaCys: 1.09 ± 0.425
4.595AlaAsp: 4.595 ± 0.588
4.984AlaGlu: 4.984 ± 0.748
2.881AlaPhe: 2.881 ± 0.392
4.517AlaGly: 4.517 ± 0.742
1.402AlaHis: 1.402 ± 0.285
4.517AlaIle: 4.517 ± 0.659
2.648AlaLys: 2.648 ± 0.409
7.71AlaLeu: 7.71 ± 1.103
1.947AlaMet: 1.947 ± 0.639
3.115AlaAsn: 3.115 ± 0.51
6.152AlaPro: 6.152 ± 0.685
2.804AlaGln: 2.804 ± 0.438
4.361AlaArg: 4.361 ± 0.691
6.074AlaSer: 6.074 ± 0.74
4.673AlaThr: 4.673 ± 0.564
5.062AlaVal: 5.062 ± 0.537
0.935AlaTrp: 0.935 ± 0.261
3.427AlaTyr: 3.427 ± 0.41
0.0AlaXaa: 0.0 ± 0.0
Cys
1.012CysAla: 1.012 ± 0.305
0.467CysCys: 0.467 ± 0.169
1.168CysAsp: 1.168 ± 0.352
0.545CysGlu: 0.545 ± 0.249
1.012CysPhe: 1.012 ± 0.245
1.48CysGly: 1.48 ± 0.341
0.701CysHis: 0.701 ± 0.238
0.623CysIle: 0.623 ± 0.234
0.779CysLys: 0.779 ± 0.302
1.168CysLeu: 1.168 ± 0.333
0.701CysMet: 0.701 ± 0.263
0.623CysAsn: 0.623 ± 0.293
1.168CysPro: 1.168 ± 0.326
0.857CysGln: 0.857 ± 0.259
1.402CysArg: 1.402 ± 0.345
1.246CysSer: 1.246 ± 0.269
1.402CysThr: 1.402 ± 0.402
1.168CysVal: 1.168 ± 0.367
0.312CysTrp: 0.312 ± 0.117
0.779CysTyr: 0.779 ± 0.203
0.0CysXaa: 0.0 ± 0.0
Asp
4.127AspAla: 4.127 ± 0.604
0.779AspCys: 0.779 ± 0.207
2.959AspAsp: 2.959 ± 0.562
3.504AspGlu: 3.504 ± 0.659
2.959AspPhe: 2.959 ± 0.458
4.283AspGly: 4.283 ± 0.546
1.402AspHis: 1.402 ± 0.331
2.57AspIle: 2.57 ± 0.422
2.103AspLys: 2.103 ± 0.424
4.361AspLeu: 4.361 ± 0.465
1.168AspMet: 1.168 ± 0.261
1.635AspAsn: 1.635 ± 0.437
4.984AspPro: 4.984 ± 0.574
2.025AspGln: 2.025 ± 0.343
4.05AspArg: 4.05 ± 0.61
4.595AspSer: 4.595 ± 0.538
3.115AspThr: 3.115 ± 0.578
2.881AspVal: 2.881 ± 0.526
0.623AspTrp: 0.623 ± 0.162
1.947AspTyr: 1.947 ± 0.335
0.0AspXaa: 0.0 ± 0.0
Glu
5.218GluAla: 5.218 ± 0.765
0.701GluCys: 0.701 ± 0.203
4.127GluAsp: 4.127 ± 0.569
7.788GluGlu: 7.788 ± 1.74
1.558GluPhe: 1.558 ± 0.337
3.816GluGly: 3.816 ± 0.469
1.558GluHis: 1.558 ± 0.345
2.57GluIle: 2.57 ± 0.363
1.869GluLys: 1.869 ± 0.504
5.841GluLeu: 5.841 ± 0.575
1.246GluMet: 1.246 ± 0.276
3.504GluAsn: 3.504 ± 0.544
2.57GluPro: 2.57 ± 0.474
2.025GluGln: 2.025 ± 0.479
3.582GluArg: 3.582 ± 0.713
4.673GluSer: 4.673 ± 0.591
3.582GluThr: 3.582 ± 0.448
3.037GluVal: 3.037 ± 0.519
0.935GluTrp: 0.935 ± 0.235
1.713GluTyr: 1.713 ± 0.366
0.0GluXaa: 0.0 ± 0.0
Phe
3.193PheAla: 3.193 ± 0.455
0.545PheCys: 0.545 ± 0.25
3.037PheAsp: 3.037 ± 0.606
2.181PheGlu: 2.181 ± 0.44
1.791PhePhe: 1.791 ± 0.346
1.558PheGly: 1.558 ± 0.368
1.713PheHis: 1.713 ± 0.339
0.935PheIle: 0.935 ± 0.266
1.947PheLys: 1.947 ± 0.381
4.595PheLeu: 4.595 ± 0.602
1.012PheMet: 1.012 ± 0.277
2.103PheAsn: 2.103 ± 0.358
2.57PhePro: 2.57 ± 0.423
0.935PheGln: 0.935 ± 0.244
3.271PheArg: 3.271 ± 0.367
2.181PheSer: 2.181 ± 0.341
2.258PheThr: 2.258 ± 0.358
3.504PheVal: 3.504 ± 0.508
1.168PheTrp: 1.168 ± 0.317
1.713PheTyr: 1.713 ± 0.258
0.0PheXaa: 0.0 ± 0.0
Gly
6.619GlyAla: 6.619 ± 0.746
0.935GlyCys: 0.935 ± 0.325
2.804GlyAsp: 2.804 ± 0.651
3.972GlyGlu: 3.972 ± 0.835
2.258GlyPhe: 2.258 ± 0.321
6.23GlyGly: 6.23 ± 0.873
1.09GlyHis: 1.09 ± 0.316
2.025GlyIle: 2.025 ± 0.467
1.869GlyLys: 1.869 ± 0.382
4.361GlyLeu: 4.361 ± 0.888
1.48GlyMet: 1.48 ± 0.297
2.181GlyAsn: 2.181 ± 0.478
2.804GlyPro: 2.804 ± 0.518
1.48GlyGln: 1.48 ± 0.299
3.972GlyArg: 3.972 ± 0.528
4.127GlySer: 4.127 ± 0.501
3.972GlyThr: 3.972 ± 0.618
5.451GlyVal: 5.451 ± 0.849
1.246GlyTrp: 1.246 ± 0.257
2.881GlyTyr: 2.881 ± 0.417
0.0GlyXaa: 0.0 ± 0.0
His
1.324HisAla: 1.324 ± 0.222
0.623HisCys: 0.623 ± 0.227
1.402HisAsp: 1.402 ± 0.343
1.246HisGlu: 1.246 ± 0.301
0.545HisPhe: 0.545 ± 0.201
1.558HisGly: 1.558 ± 0.323
1.012HisHis: 1.012 ± 0.251
1.09HisIle: 1.09 ± 0.27
0.389HisLys: 0.389 ± 0.173
2.103HisLeu: 2.103 ± 0.405
0.389HisMet: 0.389 ± 0.162
1.246HisAsn: 1.246 ± 0.238
1.713HisPro: 1.713 ± 0.397
0.857HisGln: 0.857 ± 0.308
2.336HisArg: 2.336 ± 0.346
1.012HisSer: 1.012 ± 0.232
1.168HisThr: 1.168 ± 0.293
1.635HisVal: 1.635 ± 0.461
0.234HisTrp: 0.234 ± 0.126
1.012HisTyr: 1.012 ± 0.218
0.0HisXaa: 0.0 ± 0.0
Ile
3.738IleAla: 3.738 ± 0.472
0.857IleCys: 0.857 ± 0.275
1.947IleAsp: 1.947 ± 0.296
2.025IleGlu: 2.025 ± 0.35
1.558IlePhe: 1.558 ± 0.332
2.103IleGly: 2.103 ± 0.421
0.779IleHis: 0.779 ± 0.229
1.324IleIle: 1.324 ± 0.329
1.168IleLys: 1.168 ± 0.358
3.816IleLeu: 3.816 ± 0.524
0.779IleMet: 0.779 ± 0.325
1.791IleAsn: 1.791 ± 0.396
3.037IlePro: 3.037 ± 0.36
1.324IleGln: 1.324 ± 0.304
3.037IleArg: 3.037 ± 0.422
2.881IleSer: 2.881 ± 0.434
2.804IleThr: 2.804 ± 0.683
2.57IleVal: 2.57 ± 0.391
0.389IleTrp: 0.389 ± 0.163
1.635IleTyr: 1.635 ± 0.257
0.0IleXaa: 0.0 ± 0.0
Lys
2.181LysAla: 2.181 ± 0.508
0.779LysCys: 0.779 ± 0.229
1.635LysAsp: 1.635 ± 0.341
2.492LysGlu: 2.492 ± 0.513
2.025LysPhe: 2.025 ± 0.414
1.791LysGly: 1.791 ± 0.517
0.389LysHis: 0.389 ± 0.154
1.558LysIle: 1.558 ± 0.246
2.103LysLys: 2.103 ± 0.534
3.582LysLeu: 3.582 ± 0.479
1.012LysMet: 1.012 ± 0.261
1.713LysAsn: 1.713 ± 0.37
1.869LysPro: 1.869 ± 0.374
0.935LysGln: 0.935 ± 0.219
3.816LysArg: 3.816 ± 0.668
1.635LysSer: 1.635 ± 0.51
3.037LysThr: 3.037 ± 0.601
1.869LysVal: 1.869 ± 0.375
0.545LysTrp: 0.545 ± 0.185
2.025LysTyr: 2.025 ± 0.502
0.0LysXaa: 0.0 ± 0.0
Leu
6.464LeuAla: 6.464 ± 0.616
2.025LeuCys: 2.025 ± 0.5
4.127LeuAsp: 4.127 ± 0.481
4.439LeuGlu: 4.439 ± 0.566
4.127LeuPhe: 4.127 ± 0.538
4.283LeuGly: 4.283 ± 0.513
2.492LeuHis: 2.492 ± 0.502
2.959LeuIle: 2.959 ± 0.515
3.582LeuLys: 3.582 ± 0.527
7.71LeuLeu: 7.71 ± 0.643
2.258LeuMet: 2.258 ± 0.387
3.738LeuAsn: 3.738 ± 0.439
5.062LeuPro: 5.062 ± 0.542
4.127LeuGln: 4.127 ± 0.449
6.619LeuArg: 6.619 ± 0.933
6.619LeuSer: 6.619 ± 0.568
6.931LeuThr: 6.931 ± 0.728
4.595LeuVal: 4.595 ± 0.614
1.558LeuTrp: 1.558 ± 0.251
3.66LeuTyr: 3.66 ± 0.519
0.0LeuXaa: 0.0 ± 0.0
Met
2.881MetAla: 2.881 ± 0.475
0.234MetCys: 0.234 ± 0.142
1.402MetAsp: 1.402 ± 0.304
1.168MetGlu: 1.168 ± 0.297
1.012MetPhe: 1.012 ± 0.28
1.324MetGly: 1.324 ± 0.33
0.701MetHis: 0.701 ± 0.217
0.857MetIle: 0.857 ± 0.338
1.09MetLys: 1.09 ± 0.27
2.258MetLeu: 2.258 ± 0.375
0.467MetMet: 0.467 ± 0.155
0.857MetAsn: 0.857 ± 0.204
1.246MetPro: 1.246 ± 0.239
1.09MetGln: 1.09 ± 0.242
1.791MetArg: 1.791 ± 0.358
1.869MetSer: 1.869 ± 0.395
1.168MetThr: 1.168 ± 0.333
1.48MetVal: 1.48 ± 0.348
0.078MetTrp: 0.078 ± 0.06
0.935MetTyr: 0.935 ± 0.277
0.0MetXaa: 0.0 ± 0.0
Asn
3.582AsnAla: 3.582 ± 0.621
1.09AsnCys: 1.09 ± 0.331
2.103AsnAsp: 2.103 ± 0.432
2.025AsnGlu: 2.025 ± 0.463
1.48AsnPhe: 1.48 ± 0.527
2.258AsnGly: 2.258 ± 0.45
0.701AsnHis: 0.701 ± 0.191
1.558AsnIle: 1.558 ± 0.447
1.635AsnLys: 1.635 ± 0.3
3.193AsnLeu: 3.193 ± 0.61
0.701AsnMet: 0.701 ± 0.29
1.791AsnAsn: 1.791 ± 0.431
3.894AsnPro: 3.894 ± 0.592
1.402AsnGln: 1.402 ± 0.41
2.881AsnArg: 2.881 ± 0.52
2.726AsnSer: 2.726 ± 0.629
2.648AsnThr: 2.648 ± 0.416
3.582AsnVal: 3.582 ± 0.624
0.701AsnTrp: 0.701 ± 0.319
1.947AsnTyr: 1.947 ± 0.382
0.0AsnXaa: 0.0 ± 0.0
Pro
5.529ProAla: 5.529 ± 0.827
0.857ProCys: 0.857 ± 0.218
3.271ProAsp: 3.271 ± 0.342
4.673ProGlu: 4.673 ± 0.702
3.193ProPhe: 3.193 ± 0.544
2.414ProGly: 2.414 ± 0.297
1.246ProHis: 1.246 ± 0.367
2.414ProIle: 2.414 ± 0.452
1.869ProLys: 1.869 ± 0.508
5.607ProLeu: 5.607 ± 0.739
1.402ProMet: 1.402 ± 0.367
2.959ProAsn: 2.959 ± 0.446
6.386ProPro: 6.386 ± 0.85
2.336ProGln: 2.336 ± 0.425
3.894ProArg: 3.894 ± 0.557
5.841ProSer: 5.841 ± 0.702
4.205ProThr: 4.205 ± 0.644
4.205ProVal: 4.205 ± 0.673
0.467ProTrp: 0.467 ± 0.202
3.037ProTyr: 3.037 ± 0.438
0.0ProXaa: 0.0 ± 0.0
Gln
2.804GlnAla: 2.804 ± 0.526
0.467GlnCys: 0.467 ± 0.151
1.791GlnAsp: 1.791 ± 0.314
2.336GlnGlu: 2.336 ± 0.553
1.168GlnPhe: 1.168 ± 0.293
1.713GlnGly: 1.713 ± 0.322
0.701GlnHis: 0.701 ± 0.318
1.48GlnIle: 1.48 ± 0.285
1.635GlnLys: 1.635 ± 0.316
3.66GlnLeu: 3.66 ± 0.46
1.324GlnMet: 1.324 ± 0.351
1.947GlnAsn: 1.947 ± 0.543
1.791GlnPro: 1.791 ± 0.352
2.181GlnGln: 2.181 ± 0.564
2.336GlnArg: 2.336 ± 0.416
2.103GlnSer: 2.103 ± 0.442
2.258GlnThr: 2.258 ± 0.477
2.181GlnVal: 2.181 ± 0.471
0.234GlnTrp: 0.234 ± 0.131
1.869GlnTyr: 1.869 ± 0.436
0.0GlnXaa: 0.0 ± 0.0
Arg
5.218ArgAla: 5.218 ± 0.812
1.168ArgCys: 1.168 ± 0.344
3.972ArgAsp: 3.972 ± 0.652
3.816ArgGlu: 3.816 ± 0.624
2.881ArgPhe: 2.881 ± 0.383
4.127ArgGly: 4.127 ± 0.819
2.258ArgHis: 2.258 ± 0.589
2.881ArgIle: 2.881 ± 0.506
3.037ArgLys: 3.037 ± 0.653
6.152ArgLeu: 6.152 ± 0.929
2.181ArgMet: 2.181 ± 0.351
2.959ArgAsn: 2.959 ± 0.606
4.127ArgPro: 4.127 ± 0.605
3.037ArgGln: 3.037 ± 0.406
8.255ArgArg: 8.255 ± 1.762
5.296ArgSer: 5.296 ± 0.774
3.504ArgThr: 3.504 ± 0.508
4.75ArgVal: 4.75 ± 0.596
1.012ArgTrp: 1.012 ± 0.228
2.414ArgTyr: 2.414 ± 0.38
0.0ArgXaa: 0.0 ± 0.0
Ser
4.75SerAla: 4.75 ± 0.602
1.246SerCys: 1.246 ± 0.283
5.763SerAsp: 5.763 ± 0.934
4.906SerGlu: 4.906 ± 0.667
2.648SerPhe: 2.648 ± 0.45
6.697SerGly: 6.697 ± 0.751
1.168SerHis: 1.168 ± 0.324
2.57SerIle: 2.57 ± 0.447
3.115SerLys: 3.115 ± 0.522
5.607SerLeu: 5.607 ± 0.721
1.791SerMet: 1.791 ± 0.435
2.492SerAsn: 2.492 ± 0.468
4.205SerPro: 4.205 ± 0.536
2.181SerGln: 2.181 ± 0.47
5.451SerArg: 5.451 ± 0.719
6.074SerSer: 6.074 ± 0.977
4.127SerThr: 4.127 ± 0.528
3.894SerVal: 3.894 ± 0.622
1.012SerTrp: 1.012 ± 0.316
2.025SerTyr: 2.025 ± 0.388
0.0SerXaa: 0.0 ± 0.0
Thr
6.464ThrAla: 6.464 ± 0.878
1.558ThrCys: 1.558 ± 0.316
2.726ThrAsp: 2.726 ± 0.456
4.127ThrGlu: 4.127 ± 0.399
2.492ThrPhe: 2.492 ± 0.438
4.673ThrGly: 4.673 ± 0.773
1.012ThrHis: 1.012 ± 0.273
2.726ThrIle: 2.726 ± 0.337
1.168ThrLys: 1.168 ± 0.252
5.529ThrLeu: 5.529 ± 0.556
1.09ThrMet: 1.09 ± 0.219
2.414ThrAsn: 2.414 ± 0.485
3.894ThrPro: 3.894 ± 0.575
1.869ThrGln: 1.869 ± 0.402
4.205ThrArg: 4.205 ± 0.532
3.582ThrSer: 3.582 ± 0.832
3.271ThrThr: 3.271 ± 0.479
4.906ThrVal: 4.906 ± 0.579
0.545ThrTrp: 0.545 ± 0.2
2.57ThrTyr: 2.57 ± 0.602
0.0ThrXaa: 0.0 ± 0.0
Val
4.517ValAla: 4.517 ± 0.675
1.48ValCys: 1.48 ± 0.279
3.504ValAsp: 3.504 ± 0.502
3.349ValGlu: 3.349 ± 0.47
3.504ValPhe: 3.504 ± 0.575
3.894ValGly: 3.894 ± 0.548
1.246ValHis: 1.246 ± 0.271
3.193ValIle: 3.193 ± 0.426
2.492ValLys: 2.492 ± 0.471
5.996ValLeu: 5.996 ± 0.603
1.246ValMet: 1.246 ± 0.307
2.57ValAsn: 2.57 ± 0.59
4.906ValPro: 4.906 ± 0.595
2.881ValGln: 2.881 ± 0.504
4.127ValArg: 4.127 ± 0.505
4.828ValSer: 4.828 ± 0.654
3.816ValThr: 3.816 ± 0.603
4.595ValVal: 4.595 ± 0.652
0.779ValTrp: 0.779 ± 0.246
2.492ValTyr: 2.492 ± 0.449
0.0ValXaa: 0.0 ± 0.0
Trp
0.701TrpAla: 0.701 ± 0.276
0.467TrpCys: 0.467 ± 0.224
0.857TrpAsp: 0.857 ± 0.2
0.623TrpGlu: 0.623 ± 0.157
0.623TrpPhe: 0.623 ± 0.266
0.779TrpGly: 0.779 ± 0.248
0.234TrpHis: 0.234 ± 0.128
0.545TrpIle: 0.545 ± 0.199
0.545TrpLys: 0.545 ± 0.24
1.246TrpLeu: 1.246 ± 0.3
0.156TrpMet: 0.156 ± 0.126
0.779TrpAsn: 0.779 ± 0.251
0.467TrpPro: 0.467 ± 0.342
0.623TrpGln: 0.623 ± 0.239
1.09TrpArg: 1.09 ± 0.226
1.012TrpSer: 1.012 ± 0.213
0.779TrpThr: 0.779 ± 0.243
1.168TrpVal: 1.168 ± 0.292
0.078TrpTrp: 0.078 ± 0.069
0.779TrpTyr: 0.779 ± 0.256
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.57TyrAla: 2.57 ± 0.333
1.246TyrCys: 1.246 ± 0.277
2.881TyrAsp: 2.881 ± 0.735
1.713TyrGlu: 1.713 ± 0.452
2.492TyrPhe: 2.492 ± 0.416
2.258TyrGly: 2.258 ± 0.391
1.09TyrHis: 1.09 ± 0.21
1.168TyrIle: 1.168 ± 0.279
1.947TyrLys: 1.947 ± 0.462
2.881TyrLeu: 2.881 ± 0.46
1.48TyrMet: 1.48 ± 0.357
1.48TyrAsn: 1.48 ± 0.4
2.959TyrPro: 2.959 ± 0.406
1.012TyrGln: 1.012 ± 0.262
2.57TyrArg: 2.57 ± 0.448
3.349TyrSer: 3.349 ± 0.593
2.103TyrThr: 2.103 ± 0.453
2.881TyrVal: 2.881 ± 0.345
0.779TyrTrp: 0.779 ± 0.254
1.168TyrTyr: 1.168 ± 0.202
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 37 proteins (12842 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski