Amino acid dipepetide frequency for Hubei picorna-like virus 39

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.138AlaAla: 4.138 ± 0.0
1.724AlaCys: 1.724 ± 0.0
2.069AlaAsp: 2.069 ± 0.0
4.483AlaGlu: 4.483 ± 0.0
1.724AlaPhe: 1.724 ± 0.0
3.793AlaGly: 3.793 ± 0.0
2.414AlaHis: 2.414 ± 0.0
4.138AlaIle: 4.138 ± 0.0
3.793AlaLys: 3.793 ± 0.0
6.207AlaLeu: 6.207 ± 0.0
1.724AlaMet: 1.724 ± 0.0
4.483AlaAsn: 4.483 ± 0.0
2.414AlaPro: 2.414 ± 0.0
1.724AlaGln: 1.724 ± 0.0
2.759AlaArg: 2.759 ± 0.0
8.276AlaSer: 8.276 ± 0.0
2.759AlaThr: 2.759 ± 0.0
6.207AlaVal: 6.207 ± 0.0
1.034AlaTrp: 1.034 ± 0.0
1.379AlaTyr: 1.379 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.034CysAla: 1.034 ± 0.0
0.345CysCys: 0.345 ± 0.0
1.034CysAsp: 1.034 ± 0.0
1.379CysGlu: 1.379 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.724CysGly: 1.724 ± 0.0
0.69CysHis: 0.69 ± 0.0
1.034CysIle: 1.034 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.379CysLeu: 1.379 ± 0.0
1.379CysMet: 1.379 ± 0.0
1.034CysAsn: 1.034 ± 0.0
0.69CysPro: 0.69 ± 0.0
0.69CysGln: 0.69 ± 0.0
1.379CysArg: 1.379 ± 0.0
0.69CysSer: 0.69 ± 0.0
1.379CysThr: 1.379 ± 0.0
2.069CysVal: 2.069 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.69CysTyr: 0.69 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.793AspAla: 3.793 ± 0.0
0.69AspCys: 0.69 ± 0.0
4.138AspAsp: 4.138 ± 0.0
1.724AspGlu: 1.724 ± 0.0
3.793AspPhe: 3.793 ± 0.0
1.034AspGly: 1.034 ± 0.0
1.034AspHis: 1.034 ± 0.0
2.759AspIle: 2.759 ± 0.0
2.414AspLys: 2.414 ± 0.0
6.552AspLeu: 6.552 ± 0.0
0.345AspMet: 0.345 ± 0.0
1.379AspAsn: 1.379 ± 0.0
3.103AspPro: 3.103 ± 0.0
2.759AspGln: 2.759 ± 0.0
1.379AspArg: 1.379 ± 0.0
3.103AspSer: 3.103 ± 0.0
5.517AspThr: 5.517 ± 0.0
3.448AspVal: 3.448 ± 0.0
1.379AspTrp: 1.379 ± 0.0
1.379AspTyr: 1.379 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.862GluAla: 5.862 ± 0.0
2.414GluCys: 2.414 ± 0.0
3.793GluAsp: 3.793 ± 0.0
3.448GluGlu: 3.448 ± 0.0
1.379GluPhe: 1.379 ± 0.0
2.414GluGly: 2.414 ± 0.0
2.414GluHis: 2.414 ± 0.0
3.103GluIle: 3.103 ± 0.0
5.517GluLys: 5.517 ± 0.0
3.448GluLeu: 3.448 ± 0.0
1.034GluMet: 1.034 ± 0.0
2.759GluAsn: 2.759 ± 0.0
1.379GluPro: 1.379 ± 0.0
2.069GluGln: 2.069 ± 0.0
2.414GluArg: 2.414 ± 0.0
3.448GluSer: 3.448 ± 0.0
2.414GluThr: 2.414 ± 0.0
5.517GluVal: 5.517 ± 0.0
2.069GluTrp: 2.069 ± 0.0
3.448GluTyr: 3.448 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.759PheAla: 2.759 ± 0.0
0.69PheCys: 0.69 ± 0.0
1.379PheAsp: 1.379 ± 0.0
2.759PheGlu: 2.759 ± 0.0
1.379PhePhe: 1.379 ± 0.0
2.069PheGly: 2.069 ± 0.0
1.034PheHis: 1.034 ± 0.0
2.759PheIle: 2.759 ± 0.0
3.103PheLys: 3.103 ± 0.0
3.103PheLeu: 3.103 ± 0.0
2.759PheMet: 2.759 ± 0.0
2.759PheAsn: 2.759 ± 0.0
1.724PhePro: 1.724 ± 0.0
3.103PheGln: 3.103 ± 0.0
2.414PheArg: 2.414 ± 0.0
2.414PheSer: 2.414 ± 0.0
1.724PheThr: 1.724 ± 0.0
4.138PheVal: 4.138 ± 0.0
1.379PheTrp: 1.379 ± 0.0
1.034PheTyr: 1.034 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.138GlyAla: 4.138 ± 0.0
0.0GlyCys: 0.0 ± 0.0
3.448GlyAsp: 3.448 ± 0.0
1.379GlyGlu: 1.379 ± 0.0
2.414GlyPhe: 2.414 ± 0.0
2.759GlyGly: 2.759 ± 0.0
1.034GlyHis: 1.034 ± 0.0
3.793GlyIle: 3.793 ± 0.0
3.793GlyLys: 3.793 ± 0.0
3.448GlyLeu: 3.448 ± 0.0
1.034GlyMet: 1.034 ± 0.0
0.69GlyAsn: 0.69 ± 0.0
1.379GlyPro: 1.379 ± 0.0
1.379GlyGln: 1.379 ± 0.0
1.034GlyArg: 1.034 ± 0.0
5.517GlySer: 5.517 ± 0.0
4.138GlyThr: 4.138 ± 0.0
5.862GlyVal: 5.862 ± 0.0
1.034GlyTrp: 1.034 ± 0.0
2.759GlyTyr: 2.759 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.345HisAla: 0.345 ± 0.0
0.69HisCys: 0.69 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.724HisGlu: 1.724 ± 0.0
0.345HisPhe: 0.345 ± 0.0
1.379HisGly: 1.379 ± 0.0
1.034HisHis: 1.034 ± 0.0
3.793HisIle: 3.793 ± 0.0
0.345HisLys: 0.345 ± 0.0
3.103HisLeu: 3.103 ± 0.0
0.69HisMet: 0.69 ± 0.0
1.724HisAsn: 1.724 ± 0.0
0.69HisPro: 0.69 ± 0.0
1.034HisGln: 1.034 ± 0.0
0.69HisArg: 0.69 ± 0.0
2.414HisSer: 2.414 ± 0.0
1.724HisThr: 1.724 ± 0.0
1.379HisVal: 1.379 ± 0.0
0.69HisTrp: 0.69 ± 0.0
1.724HisTyr: 1.724 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.828IleAla: 4.828 ± 0.0
1.379IleCys: 1.379 ± 0.0
2.759IleAsp: 2.759 ± 0.0
2.414IleGlu: 2.414 ± 0.0
3.103IlePhe: 3.103 ± 0.0
2.414IleGly: 2.414 ± 0.0
0.345IleHis: 0.345 ± 0.0
2.759IleIle: 2.759 ± 0.0
4.828IleLys: 4.828 ± 0.0
4.483IleLeu: 4.483 ± 0.0
2.759IleMet: 2.759 ± 0.0
2.759IleAsn: 2.759 ± 0.0
3.448IlePro: 3.448 ± 0.0
2.759IleGln: 2.759 ± 0.0
2.759IleArg: 2.759 ± 0.0
3.448IleSer: 3.448 ± 0.0
4.828IleThr: 4.828 ± 0.0
3.448IleVal: 3.448 ± 0.0
0.345IleTrp: 0.345 ± 0.0
4.483IleTyr: 4.483 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.828LysAla: 4.828 ± 0.0
0.69LysCys: 0.69 ± 0.0
3.793LysAsp: 3.793 ± 0.0
5.172LysGlu: 5.172 ± 0.0
3.793LysPhe: 3.793 ± 0.0
2.414LysGly: 2.414 ± 0.0
1.034LysHis: 1.034 ± 0.0
3.793LysIle: 3.793 ± 0.0
3.103LysLys: 3.103 ± 0.0
4.138LysLeu: 4.138 ± 0.0
0.0LysMet: 0.0 ± 0.0
1.034LysAsn: 1.034 ± 0.0
2.759LysPro: 2.759 ± 0.0
2.069LysGln: 2.069 ± 0.0
3.793LysArg: 3.793 ± 0.0
4.828LysSer: 4.828 ± 0.0
3.103LysThr: 3.103 ± 0.0
2.414LysVal: 2.414 ± 0.0
0.345LysTrp: 0.345 ± 0.0
1.034LysTyr: 1.034 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.517LeuAla: 5.517 ± 0.0
2.069LeuCys: 2.069 ± 0.0
3.103LeuAsp: 3.103 ± 0.0
7.241LeuGlu: 7.241 ± 0.0
4.483LeuPhe: 4.483 ± 0.0
5.862LeuGly: 5.862 ± 0.0
2.759LeuHis: 2.759 ± 0.0
3.103LeuIle: 3.103 ± 0.0
4.828LeuLys: 4.828 ± 0.0
8.966LeuLeu: 8.966 ± 0.0
1.379LeuMet: 1.379 ± 0.0
5.172LeuAsn: 5.172 ± 0.0
3.793LeuPro: 3.793 ± 0.0
2.759LeuGln: 2.759 ± 0.0
5.172LeuArg: 5.172 ± 0.0
9.655LeuSer: 9.655 ± 0.0
6.552LeuThr: 6.552 ± 0.0
6.552LeuVal: 6.552 ± 0.0
0.345LeuTrp: 0.345 ± 0.0
2.414LeuTyr: 2.414 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.379MetAla: 1.379 ± 0.0
0.69MetCys: 0.69 ± 0.0
2.759MetAsp: 2.759 ± 0.0
1.724MetGlu: 1.724 ± 0.0
1.724MetPhe: 1.724 ± 0.0
0.345MetGly: 0.345 ± 0.0
1.379MetHis: 1.379 ± 0.0
1.379MetIle: 1.379 ± 0.0
2.069MetLys: 2.069 ± 0.0
3.793MetLeu: 3.793 ± 0.0
0.345MetMet: 0.345 ± 0.0
1.379MetAsn: 1.379 ± 0.0
2.069MetPro: 2.069 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.724MetArg: 1.724 ± 0.0
0.69MetSer: 0.69 ± 0.0
0.69MetThr: 0.69 ± 0.0
2.759MetVal: 2.759 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.345MetTyr: 0.345 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.793AsnAla: 3.793 ± 0.0
0.69AsnCys: 0.69 ± 0.0
1.724AsnAsp: 1.724 ± 0.0
1.034AsnGlu: 1.034 ± 0.0
1.034AsnPhe: 1.034 ± 0.0
2.414AsnGly: 2.414 ± 0.0
0.69AsnHis: 0.69 ± 0.0
4.138AsnIle: 4.138 ± 0.0
1.724AsnLys: 1.724 ± 0.0
3.103AsnLeu: 3.103 ± 0.0
1.379AsnMet: 1.379 ± 0.0
2.414AsnAsn: 2.414 ± 0.0
3.103AsnPro: 3.103 ± 0.0
3.103AsnGln: 3.103 ± 0.0
0.69AsnArg: 0.69 ± 0.0
3.103AsnSer: 3.103 ± 0.0
3.103AsnThr: 3.103 ± 0.0
4.138AsnVal: 4.138 ± 0.0
0.69AsnTrp: 0.69 ± 0.0
2.069AsnTyr: 2.069 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.724ProAla: 1.724 ± 0.0
1.034ProCys: 1.034 ± 0.0
2.759ProAsp: 2.759 ± 0.0
1.724ProGlu: 1.724 ± 0.0
3.448ProPhe: 3.448 ± 0.0
2.069ProGly: 2.069 ± 0.0
0.69ProHis: 0.69 ± 0.0
1.724ProIle: 1.724 ± 0.0
2.069ProLys: 2.069 ± 0.0
3.793ProLeu: 3.793 ± 0.0
1.724ProMet: 1.724 ± 0.0
1.034ProAsn: 1.034 ± 0.0
0.69ProPro: 0.69 ± 0.0
1.379ProGln: 1.379 ± 0.0
2.069ProArg: 2.069 ± 0.0
5.172ProSer: 5.172 ± 0.0
2.069ProThr: 2.069 ± 0.0
2.414ProVal: 2.414 ± 0.0
1.034ProTrp: 1.034 ± 0.0
3.448ProTyr: 3.448 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.759GlnAla: 2.759 ± 0.0
0.69GlnCys: 0.69 ± 0.0
2.069GlnAsp: 2.069 ± 0.0
1.724GlnGlu: 1.724 ± 0.0
2.069GlnPhe: 2.069 ± 0.0
2.759GlnGly: 2.759 ± 0.0
0.345GlnHis: 0.345 ± 0.0
3.103GlnIle: 3.103 ± 0.0
1.724GlnLys: 1.724 ± 0.0
3.103GlnLeu: 3.103 ± 0.0
2.759GlnMet: 2.759 ± 0.0
1.724GlnAsn: 1.724 ± 0.0
0.69GlnPro: 0.69 ± 0.0
1.724GlnGln: 1.724 ± 0.0
1.724GlnArg: 1.724 ± 0.0
3.448GlnSer: 3.448 ± 0.0
3.103GlnThr: 3.103 ± 0.0
3.793GlnVal: 3.793 ± 0.0
0.345GlnTrp: 0.345 ± 0.0
0.69GlnTyr: 0.69 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.448ArgAla: 3.448 ± 0.0
0.345ArgCys: 0.345 ± 0.0
3.793ArgAsp: 3.793 ± 0.0
3.103ArgGlu: 3.103 ± 0.0
3.103ArgPhe: 3.103 ± 0.0
1.379ArgGly: 1.379 ± 0.0
1.379ArgHis: 1.379 ± 0.0
1.379ArgIle: 1.379 ± 0.0
2.414ArgLys: 2.414 ± 0.0
5.172ArgLeu: 5.172 ± 0.0
0.345ArgMet: 0.345 ± 0.0
3.448ArgAsn: 3.448 ± 0.0
2.759ArgPro: 2.759 ± 0.0
0.69ArgGln: 0.69 ± 0.0
2.069ArgArg: 2.069 ± 0.0
2.069ArgSer: 2.069 ± 0.0
1.379ArgThr: 1.379 ± 0.0
2.759ArgVal: 2.759 ± 0.0
0.69ArgTrp: 0.69 ± 0.0
2.414ArgTyr: 2.414 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.517SerAla: 5.517 ± 0.0
1.034SerCys: 1.034 ± 0.0
3.103SerAsp: 3.103 ± 0.0
6.207SerGlu: 6.207 ± 0.0
3.793SerPhe: 3.793 ± 0.0
5.172SerGly: 5.172 ± 0.0
3.448SerHis: 3.448 ± 0.0
3.103SerIle: 3.103 ± 0.0
3.793SerLys: 3.793 ± 0.0
9.31SerLeu: 9.31 ± 0.0
1.724SerMet: 1.724 ± 0.0
2.759SerAsn: 2.759 ± 0.0
3.103SerPro: 3.103 ± 0.0
3.103SerGln: 3.103 ± 0.0
2.414SerArg: 2.414 ± 0.0
5.517SerSer: 5.517 ± 0.0
6.552SerThr: 6.552 ± 0.0
2.759SerVal: 2.759 ± 0.0
1.379SerTrp: 1.379 ± 0.0
3.103SerTyr: 3.103 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.103ThrAla: 3.103 ± 0.0
1.034ThrCys: 1.034 ± 0.0
3.103ThrAsp: 3.103 ± 0.0
4.828ThrGlu: 4.828 ± 0.0
3.103ThrPhe: 3.103 ± 0.0
3.103ThrGly: 3.103 ± 0.0
1.379ThrHis: 1.379 ± 0.0
6.897ThrIle: 6.897 ± 0.0
3.448ThrLys: 3.448 ± 0.0
6.552ThrLeu: 6.552 ± 0.0
1.724ThrMet: 1.724 ± 0.0
2.414ThrAsn: 2.414 ± 0.0
2.759ThrPro: 2.759 ± 0.0
2.759ThrGln: 2.759 ± 0.0
4.138ThrArg: 4.138 ± 0.0
4.138ThrSer: 4.138 ± 0.0
4.138ThrThr: 4.138 ± 0.0
5.517ThrVal: 5.517 ± 0.0
0.69ThrTrp: 0.69 ± 0.0
1.379ThrTyr: 1.379 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.172ValAla: 5.172 ± 0.0
1.379ValCys: 1.379 ± 0.0
3.103ValAsp: 3.103 ± 0.0
4.483ValGlu: 4.483 ± 0.0
2.759ValPhe: 2.759 ± 0.0
5.172ValGly: 5.172 ± 0.0
1.379ValHis: 1.379 ± 0.0
3.103ValIle: 3.103 ± 0.0
3.103ValLys: 3.103 ± 0.0
7.241ValLeu: 7.241 ± 0.0
1.724ValMet: 1.724 ± 0.0
5.172ValAsn: 5.172 ± 0.0
4.138ValPro: 4.138 ± 0.0
4.828ValGln: 4.828 ± 0.0
3.103ValArg: 3.103 ± 0.0
4.483ValSer: 4.483 ± 0.0
4.828ValThr: 4.828 ± 0.0
9.31ValVal: 9.31 ± 0.0
1.379ValTrp: 1.379 ± 0.0
2.414ValTyr: 2.414 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.034TrpAla: 1.034 ± 0.0
0.345TrpCys: 0.345 ± 0.0
0.69TrpAsp: 0.69 ± 0.0
1.379TrpGlu: 1.379 ± 0.0
0.345TrpPhe: 0.345 ± 0.0
0.69TrpGly: 0.69 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.724TrpIle: 1.724 ± 0.0
0.345TrpLys: 0.345 ± 0.0
1.724TrpLeu: 1.724 ± 0.0
1.034TrpMet: 1.034 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.69TrpArg: 0.69 ± 0.0
1.724TrpSer: 1.724 ± 0.0
1.724TrpThr: 1.724 ± 0.0
1.034TrpVal: 1.034 ± 0.0
0.69TrpTrp: 0.69 ± 0.0
0.69TrpTyr: 0.69 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.069TyrAla: 2.069 ± 0.0
0.69TyrCys: 0.69 ± 0.0
3.103TyrAsp: 3.103 ± 0.0
2.414TyrGlu: 2.414 ± 0.0
0.69TyrPhe: 0.69 ± 0.0
2.414TyrGly: 2.414 ± 0.0
1.034TyrHis: 1.034 ± 0.0
2.759TyrIle: 2.759 ± 0.0
1.724TyrLys: 1.724 ± 0.0
3.103TyrLeu: 3.103 ± 0.0
1.034TyrMet: 1.034 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
1.379TyrPro: 1.379 ± 0.0
2.414TyrGln: 2.414 ± 0.0
1.724TyrArg: 1.724 ± 0.0
2.759TyrSer: 2.759 ± 0.0
4.483TyrThr: 4.483 ± 0.0
2.759TyrVal: 2.759 ± 0.0
0.345TyrTrp: 0.345 ± 0.0
2.759TyrTyr: 2.759 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2901 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski