Amino acid dipepetide frequency for Swagivirus HG

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.969AlaAla: 1.969 ± 0.0
0.984AlaCys: 0.984 ± 0.0
2.953AlaAsp: 2.953 ± 0.0
5.906AlaGlu: 5.906 ± 0.0
1.969AlaPhe: 1.969 ± 0.0
2.953AlaGly: 2.953 ± 0.0
0.984AlaHis: 0.984 ± 0.0
0.0AlaIle: 0.0 ± 0.0
2.953AlaLys: 2.953 ± 0.0
4.921AlaLeu: 4.921 ± 0.0
0.984AlaMet: 0.984 ± 0.0
1.969AlaAsn: 1.969 ± 0.0
1.969AlaPro: 1.969 ± 0.0
1.969AlaGln: 1.969 ± 0.0
2.953AlaArg: 2.953 ± 0.0
3.937AlaSer: 3.937 ± 0.0
3.937AlaThr: 3.937 ± 0.0
7.874AlaVal: 7.874 ± 0.0
0.984AlaTrp: 0.984 ± 0.0
2.953AlaTyr: 2.953 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.984CysAla: 0.984 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.953CysAsp: 2.953 ± 0.0
0.984CysGlu: 0.984 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.969CysGly: 1.969 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.969CysIle: 1.969 ± 0.0
0.984CysLys: 0.984 ± 0.0
0.984CysLeu: 0.984 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.969CysAsn: 1.969 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
4.921CysArg: 4.921 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.969CysVal: 1.969 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.969AspAla: 1.969 ± 0.0
1.969AspCys: 1.969 ± 0.0
4.921AspAsp: 4.921 ± 0.0
7.874AspGlu: 7.874 ± 0.0
5.906AspPhe: 5.906 ± 0.0
2.953AspGly: 2.953 ± 0.0
1.969AspHis: 1.969 ± 0.0
2.953AspIle: 2.953 ± 0.0
4.921AspLys: 4.921 ± 0.0
10.827AspLeu: 10.827 ± 0.0
1.969AspMet: 1.969 ± 0.0
0.984AspAsn: 0.984 ± 0.0
3.937AspPro: 3.937 ± 0.0
3.937AspGln: 3.937 ± 0.0
1.969AspArg: 1.969 ± 0.0
3.937AspSer: 3.937 ± 0.0
0.0AspThr: 0.0 ± 0.0
0.984AspVal: 0.984 ± 0.0
1.969AspTrp: 1.969 ± 0.0
3.937AspTyr: 3.937 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.906GluAla: 5.906 ± 0.0
0.0GluCys: 0.0 ± 0.0
2.953GluAsp: 2.953 ± 0.0
4.921GluGlu: 4.921 ± 0.0
4.921GluPhe: 4.921 ± 0.0
3.937GluGly: 3.937 ± 0.0
0.0GluHis: 0.0 ± 0.0
4.921GluIle: 4.921 ± 0.0
0.984GluLys: 0.984 ± 0.0
3.937GluLeu: 3.937 ± 0.0
2.953GluMet: 2.953 ± 0.0
0.984GluAsn: 0.984 ± 0.0
0.984GluPro: 0.984 ± 0.0
4.921GluGln: 4.921 ± 0.0
3.937GluArg: 3.937 ± 0.0
4.921GluSer: 4.921 ± 0.0
3.937GluThr: 3.937 ± 0.0
6.89GluVal: 6.89 ± 0.0
0.984GluTrp: 0.984 ± 0.0
2.953GluTyr: 2.953 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.937PheAla: 3.937 ± 0.0
0.984PheCys: 0.984 ± 0.0
7.874PheAsp: 7.874 ± 0.0
2.953PheGlu: 2.953 ± 0.0
3.937PhePhe: 3.937 ± 0.0
1.969PheGly: 1.969 ± 0.0
0.984PheHis: 0.984 ± 0.0
1.969PheIle: 1.969 ± 0.0
2.953PheLys: 2.953 ± 0.0
3.937PheLeu: 3.937 ± 0.0
1.969PheMet: 1.969 ± 0.0
1.969PheAsn: 1.969 ± 0.0
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
1.969PheArg: 1.969 ± 0.0
5.906PheSer: 5.906 ± 0.0
3.937PheThr: 3.937 ± 0.0
4.921PheVal: 4.921 ± 0.0
2.953PheTrp: 2.953 ± 0.0
2.953PheTyr: 2.953 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.984GlyAla: 0.984 ± 0.0
0.984GlyCys: 0.984 ± 0.0
0.984GlyAsp: 0.984 ± 0.0
4.921GlyGlu: 4.921 ± 0.0
3.937GlyPhe: 3.937 ± 0.0
2.953GlyGly: 2.953 ± 0.0
2.953GlyHis: 2.953 ± 0.0
6.89GlyIle: 6.89 ± 0.0
1.969GlyLys: 1.969 ± 0.0
3.937GlyLeu: 3.937 ± 0.0
0.984GlyMet: 0.984 ± 0.0
1.969GlyAsn: 1.969 ± 0.0
0.984GlyPro: 0.984 ± 0.0
1.969GlyGln: 1.969 ± 0.0
2.953GlyArg: 2.953 ± 0.0
3.937GlySer: 3.937 ± 0.0
1.969GlyThr: 1.969 ± 0.0
1.969GlyVal: 1.969 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.984HisCys: 0.984 ± 0.0
2.953HisAsp: 2.953 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.984HisGly: 0.984 ± 0.0
1.969HisHis: 1.969 ± 0.0
0.984HisIle: 0.984 ± 0.0
0.0HisLys: 0.0 ± 0.0
0.984HisLeu: 0.984 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.969HisAsn: 1.969 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.953HisArg: 2.953 ± 0.0
1.969HisSer: 1.969 ± 0.0
0.0HisThr: 0.0 ± 0.0
2.953HisVal: 2.953 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.984HisTyr: 0.984 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.937IleAla: 3.937 ± 0.0
0.984IleCys: 0.984 ± 0.0
3.937IleAsp: 3.937 ± 0.0
2.953IleGlu: 2.953 ± 0.0
4.921IlePhe: 4.921 ± 0.0
5.906IleGly: 5.906 ± 0.0
0.0IleHis: 0.0 ± 0.0
0.984IleIle: 0.984 ± 0.0
0.984IleLys: 0.984 ± 0.0
5.906IleLeu: 5.906 ± 0.0
0.0IleMet: 0.0 ± 0.0
0.984IleAsn: 0.984 ± 0.0
3.937IlePro: 3.937 ± 0.0
0.984IleGln: 0.984 ± 0.0
2.953IleArg: 2.953 ± 0.0
6.89IleSer: 6.89 ± 0.0
7.874IleThr: 7.874 ± 0.0
6.89IleVal: 6.89 ± 0.0
0.0IleTrp: 0.0 ± 0.0
1.969IleTyr: 1.969 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.953LysAla: 2.953 ± 0.0
0.984LysCys: 0.984 ± 0.0
6.89LysAsp: 6.89 ± 0.0
3.937LysGlu: 3.937 ± 0.0
3.937LysPhe: 3.937 ± 0.0
3.937LysGly: 3.937 ± 0.0
0.984LysHis: 0.984 ± 0.0
7.874LysIle: 7.874 ± 0.0
5.906LysLys: 5.906 ± 0.0
6.89LysLeu: 6.89 ± 0.0
0.984LysMet: 0.984 ± 0.0
2.953LysAsn: 2.953 ± 0.0
2.953LysPro: 2.953 ± 0.0
0.0LysGln: 0.0 ± 0.0
1.969LysArg: 1.969 ± 0.0
3.937LysSer: 3.937 ± 0.0
0.984LysThr: 0.984 ± 0.0
2.953LysVal: 2.953 ± 0.0
0.0LysTrp: 0.0 ± 0.0
3.937LysTyr: 3.937 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.906LeuAla: 5.906 ± 0.0
1.969LeuCys: 1.969 ± 0.0
6.89LeuAsp: 6.89 ± 0.0
1.969LeuGlu: 1.969 ± 0.0
2.953LeuPhe: 2.953 ± 0.0
3.937LeuGly: 3.937 ± 0.0
1.969LeuHis: 1.969 ± 0.0
6.89LeuIle: 6.89 ± 0.0
8.858LeuLys: 8.858 ± 0.0
4.921LeuLeu: 4.921 ± 0.0
1.969LeuMet: 1.969 ± 0.0
6.89LeuAsn: 6.89 ± 0.0
3.937LeuPro: 3.937 ± 0.0
0.984LeuGln: 0.984 ± 0.0
5.906LeuArg: 5.906 ± 0.0
6.89LeuSer: 6.89 ± 0.0
3.937LeuThr: 3.937 ± 0.0
6.89LeuVal: 6.89 ± 0.0
1.969LeuTrp: 1.969 ± 0.0
1.969LeuTyr: 1.969 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.953MetAla: 2.953 ± 0.0
0.984MetCys: 0.984 ± 0.0
1.969MetAsp: 1.969 ± 0.0
0.0MetGlu: 0.0 ± 0.0
4.921MetPhe: 4.921 ± 0.0
0.984MetGly: 0.984 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.984MetIle: 0.984 ± 0.0
1.969MetLys: 1.969 ± 0.0
3.937MetLeu: 3.937 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.984MetAsn: 0.984 ± 0.0
0.984MetPro: 0.984 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.984MetArg: 0.984 ± 0.0
2.953MetSer: 2.953 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.969MetVal: 1.969 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.984MetTyr: 0.984 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.937AsnAla: 3.937 ± 0.0
0.984AsnCys: 0.984 ± 0.0
1.969AsnAsp: 1.969 ± 0.0
5.906AsnGlu: 5.906 ± 0.0
1.969AsnPhe: 1.969 ± 0.0
0.984AsnGly: 0.984 ± 0.0
0.0AsnHis: 0.0 ± 0.0
4.921AsnIle: 4.921 ± 0.0
0.984AsnLys: 0.984 ± 0.0
5.906AsnLeu: 5.906 ± 0.0
0.0AsnMet: 0.0 ± 0.0
4.921AsnAsn: 4.921 ± 0.0
4.921AsnPro: 4.921 ± 0.0
0.984AsnGln: 0.984 ± 0.0
3.937AsnArg: 3.937 ± 0.0
4.921AsnSer: 4.921 ± 0.0
0.0AsnThr: 0.0 ± 0.0
2.953AsnVal: 2.953 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
1.969AsnTyr: 1.969 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.937ProAla: 3.937 ± 0.0
0.0ProCys: 0.0 ± 0.0
1.969ProAsp: 1.969 ± 0.0
3.937ProGlu: 3.937 ± 0.0
2.953ProPhe: 2.953 ± 0.0
1.969ProGly: 1.969 ± 0.0
0.0ProHis: 0.0 ± 0.0
4.921ProIle: 4.921 ± 0.0
0.0ProLys: 0.0 ± 0.0
0.984ProLeu: 0.984 ± 0.0
0.984ProMet: 0.984 ± 0.0
2.953ProAsn: 2.953 ± 0.0
0.984ProPro: 0.984 ± 0.0
0.984ProGln: 0.984 ± 0.0
1.969ProArg: 1.969 ± 0.0
2.953ProSer: 2.953 ± 0.0
1.969ProThr: 1.969 ± 0.0
1.969ProVal: 1.969 ± 0.0
0.0ProTrp: 0.0 ± 0.0
0.984ProTyr: 0.984 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.969GlnAla: 1.969 ± 0.0
0.984GlnCys: 0.984 ± 0.0
0.984GlnAsp: 0.984 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
0.984GlnPhe: 0.984 ± 0.0
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.969GlnLys: 1.969 ± 0.0
0.984GlnLeu: 0.984 ± 0.0
3.937GlnMet: 3.937 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
2.953GlnPro: 2.953 ± 0.0
1.969GlnGln: 1.969 ± 0.0
1.969GlnArg: 1.969 ± 0.0
1.969GlnSer: 1.969 ± 0.0
2.953GlnThr: 2.953 ± 0.0
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.984ArgAla: 0.984 ± 0.0
0.984ArgCys: 0.984 ± 0.0
1.969ArgAsp: 1.969 ± 0.0
5.906ArgGlu: 5.906 ± 0.0
4.921ArgPhe: 4.921 ± 0.0
1.969ArgGly: 1.969 ± 0.0
3.937ArgHis: 3.937 ± 0.0
6.89ArgIle: 6.89 ± 0.0
3.937ArgLys: 3.937 ± 0.0
6.89ArgLeu: 6.89 ± 0.0
0.0ArgMet: 0.0 ± 0.0
1.969ArgAsn: 1.969 ± 0.0
1.969ArgPro: 1.969 ± 0.0
0.0ArgGln: 0.0 ± 0.0
2.953ArgArg: 2.953 ± 0.0
1.969ArgSer: 1.969 ± 0.0
2.953ArgThr: 2.953 ± 0.0
5.906ArgVal: 5.906 ± 0.0
0.984ArgTrp: 0.984 ± 0.0
3.937ArgTyr: 3.937 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.906SerAla: 5.906 ± 0.0
0.0SerCys: 0.0 ± 0.0
8.858SerAsp: 8.858 ± 0.0
2.953SerGlu: 2.953 ± 0.0
4.921SerPhe: 4.921 ± 0.0
4.921SerGly: 4.921 ± 0.0
0.0SerHis: 0.0 ± 0.0
0.984SerIle: 0.984 ± 0.0
8.858SerLys: 8.858 ± 0.0
6.89SerLeu: 6.89 ± 0.0
5.906SerMet: 5.906 ± 0.0
4.921SerAsn: 4.921 ± 0.0
0.984SerPro: 0.984 ± 0.0
0.984SerGln: 0.984 ± 0.0
2.953SerArg: 2.953 ± 0.0
2.953SerSer: 2.953 ± 0.0
0.984SerThr: 0.984 ± 0.0
5.906SerVal: 5.906 ± 0.0
0.0SerTrp: 0.0 ± 0.0
0.984SerTyr: 0.984 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
1.969ThrAla: 1.969 ± 0.0
0.0ThrCys: 0.0 ± 0.0
0.984ThrAsp: 0.984 ± 0.0
0.984ThrGlu: 0.984 ± 0.0
1.969ThrPhe: 1.969 ± 0.0
0.984ThrGly: 0.984 ± 0.0
0.984ThrHis: 0.984 ± 0.0
2.953ThrIle: 2.953 ± 0.0
3.937ThrLys: 3.937 ± 0.0
5.906ThrLeu: 5.906 ± 0.0
0.0ThrMet: 0.0 ± 0.0
3.937ThrAsn: 3.937 ± 0.0
1.969ThrPro: 1.969 ± 0.0
0.0ThrGln: 0.0 ± 0.0
5.906ThrArg: 5.906 ± 0.0
4.921ThrSer: 4.921 ± 0.0
1.969ThrThr: 1.969 ± 0.0
2.953ThrVal: 2.953 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
1.969ThrTyr: 1.969 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.953ValAla: 2.953 ± 0.0
3.937ValCys: 3.937 ± 0.0
4.921ValAsp: 4.921 ± 0.0
6.89ValGlu: 6.89 ± 0.0
0.984ValPhe: 0.984 ± 0.0
2.953ValGly: 2.953 ± 0.0
1.969ValHis: 1.969 ± 0.0
1.969ValIle: 1.969 ± 0.0
8.858ValLys: 8.858 ± 0.0
7.874ValLeu: 7.874 ± 0.0
1.969ValMet: 1.969 ± 0.0
7.874ValAsn: 7.874 ± 0.0
0.984ValPro: 0.984 ± 0.0
2.953ValGln: 2.953 ± 0.0
3.937ValArg: 3.937 ± 0.0
3.937ValSer: 3.937 ± 0.0
1.969ValThr: 1.969 ± 0.0
8.858ValVal: 8.858 ± 0.0
0.984ValTrp: 0.984 ± 0.0
3.937ValTyr: 3.937 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.984TrpHis: 0.984 ± 0.0
1.969TrpIle: 1.969 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.969TrpArg: 1.969 ± 0.0
0.0TrpSer: 0.0 ± 0.0
2.953TrpThr: 2.953 ± 0.0
0.984TrpVal: 0.984 ± 0.0
0.984TrpTrp: 0.984 ± 0.0
1.969TrpTyr: 1.969 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.969TyrAla: 1.969 ± 0.0
1.969TyrCys: 1.969 ± 0.0
2.953TyrAsp: 2.953 ± 0.0
2.953TyrGlu: 2.953 ± 0.0
1.969TyrPhe: 1.969 ± 0.0
0.984TyrGly: 0.984 ± 0.0
0.0TyrHis: 0.0 ± 0.0
1.969TyrIle: 1.969 ± 0.0
3.937TyrLys: 3.937 ± 0.0
0.984TyrLeu: 0.984 ± 0.0
1.969TyrMet: 1.969 ± 0.0
1.969TyrAsn: 1.969 ± 0.0
1.969TyrPro: 1.969 ± 0.0
0.984TyrGln: 0.984 ± 0.0
1.969TyrArg: 1.969 ± 0.0
2.953TyrSer: 2.953 ± 0.0
1.969TyrThr: 1.969 ± 0.0
4.921TyrVal: 4.921 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
1.969TyrTyr: 1.969 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (1017 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski