Amino acid dipepetide frequency for Flavilitoribacter nigricans DSM 23189 = NBRC 102662

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.644AlaAla: 6.644 ± 0.059	0.936AlaCys: 0.936 ± 0.046	4.838AlaAsp: 4.838 ± 0.051	4.931AlaGlu: 4.931 ± 0.047	3.542AlaPhe: 3.542 ± 0.038	6.4AlaGly: 6.4 ± 0.064	1.304AlaHis: 1.304 ± 0.02	4.862AlaIle: 4.862 ± 0.044	3.083AlaLys: 3.083 ± 0.035	7.262AlaLeu: 7.262 ± 0.066	1.676AlaMet: 1.676 ± 0.028	3.172AlaAsn: 3.172 ± 0.043	3.148AlaPro: 3.148 ± 0.061	2.87AlaGln: 2.87 ± 0.031	3.654AlaArg: 3.654 ± 0.041	4.178AlaSer: 4.178 ± 0.045	4.197AlaThr: 4.197 ± 0.059	4.773AlaVal: 4.773 ± 0.045	0.992AlaTrp: 0.992 ± 0.019	3.074AlaTyr: 3.074 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	0.626CysAla: 0.626 ± 0.021	0.133CysCys: 0.133 ± 0.007	0.687CysAsp: 0.687 ± 0.048	0.568CysGlu: 0.568 ± 0.026	0.433CysPhe: 0.433 ± 0.015	0.765CysGly: 0.765 ± 0.035	0.215CysHis: 0.215 ± 0.009	0.478CysIle: 0.478 ± 0.013	0.325CysLys: 0.325 ± 0.01	0.911CysLeu: 0.911 ± 0.029	0.158CysMet: 0.158 ± 0.007	0.416CysAsn: 0.416 ± 0.02	0.521CysPro: 0.521 ± 0.029	0.331CysGln: 0.331 ± 0.011	0.491CysArg: 0.491 ± 0.013	0.624CysSer: 0.624 ± 0.018	0.623CysThr: 0.623 ± 0.027	0.444CysVal: 0.444 ± 0.015	0.111CysTrp: 0.111 ± 0.006	0.325CysTyr: 0.325 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.3AspAla: 4.3 ± 0.052	0.682AspCys: 0.682 ± 0.057	3.319AspAsp: 3.319 ± 0.075	3.809AspGlu: 3.809 ± 0.047	3.27AspPhe: 3.27 ± 0.034	5.199AspGly: 5.199 ± 0.072	1.353AspHis: 1.353 ± 0.026	3.787AspIle: 3.787 ± 0.057	2.463AspLys: 2.463 ± 0.03	6.624AspLeu: 6.624 ± 0.07	1.121AspMet: 1.121 ± 0.021	2.657AspAsn: 2.657 ± 0.046	3.429AspPro: 3.429 ± 0.041	2.999AspGln: 2.999 ± 0.033	3.551AspArg: 3.551 ± 0.045	2.996AspSer: 2.996 ± 0.054	3.044AspThr: 3.044 ± 0.084	3.258AspVal: 3.258 ± 0.051	1.102AspTrp: 1.102 ± 0.019	2.719AspTyr: 2.719 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	5.468GluAla: 5.468 ± 0.056	0.442GluCys: 0.442 ± 0.026	3.855GluAsp: 3.855 ± 0.037	4.806GluGlu: 4.806 ± 0.061	2.503GluPhe: 2.503 ± 0.031	4.166GluGly: 4.166 ± 0.046	1.235GluHis: 1.235 ± 0.025	4.409GluIle: 4.409 ± 0.041	4.055GluLys: 4.055 ± 0.054	6.677GluLeu: 6.677 ± 0.057	1.735GluMet: 1.735 ± 0.023	3.228GluAsn: 3.228 ± 0.036	2.26GluPro: 2.26 ± 0.025	3.057GluGln: 3.057 ± 0.037	3.428GluArg: 3.428 ± 0.039	3.383GluSer: 3.383 ± 0.033	3.479GluThr: 3.479 ± 0.042	4.498GluVal: 4.498 ± 0.04	0.895GluTrp: 0.895 ± 0.02	2.149GluTyr: 2.149 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	3.234PheAla: 3.234 ± 0.033	0.442PheCys: 0.442 ± 0.012	3.002PheAsp: 3.002 ± 0.031	2.763PheGlu: 2.763 ± 0.033	2.465PhePhe: 2.465 ± 0.035	3.483PheGly: 3.483 ± 0.039	0.932PheHis: 0.932 ± 0.02	2.719PheIle: 2.719 ± 0.038	1.895PheLys: 1.895 ± 0.028	4.545PheLeu: 4.545 ± 0.05	0.893PheMet: 0.893 ± 0.018	2.279PheAsn: 2.279 ± 0.029	2.053PhePro: 2.053 ± 0.027	1.899PheGln: 1.899 ± 0.029	2.757PheArg: 2.757 ± 0.035	3.584PheSer: 3.584 ± 0.035	3.036PheThr: 3.036 ± 0.041	2.594PheVal: 2.594 ± 0.031	0.708PheTrp: 0.708 ± 0.015	1.864PheTyr: 1.864 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	5.048GlyAla: 5.048 ± 0.05	0.827GlyCys: 0.827 ± 0.034	4.401GlyAsp: 4.401 ± 0.077	4.351GlyGlu: 4.351 ± 0.041	3.427GlyPhe: 3.427 ± 0.039	5.659GlyGly: 5.659 ± 0.072	1.327GlyHis: 1.327 ± 0.024	4.966GlyIle: 4.966 ± 0.047	4.04GlyLys: 4.04 ± 0.046	7.022GlyLeu: 7.022 ± 0.054	1.824GlyMet: 1.824 ± 0.026	3.73GlyAsn: 3.73 ± 0.05	2.348GlyPro: 2.348 ± 0.035	3.091GlyGln: 3.091 ± 0.034	3.614GlyArg: 3.614 ± 0.043	4.645GlySer: 4.645 ± 0.055	4.699GlyThr: 4.699 ± 0.075	4.4GlyVal: 4.4 ± 0.046	1.122GlyTrp: 1.122 ± 0.021	2.82GlyTyr: 2.82 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	1.155HisAla: 1.155 ± 0.022	0.21HisCys: 0.21 ± 0.008	0.916HisAsp: 0.916 ± 0.02	1.011HisGlu: 1.011 ± 0.022	1.264HisPhe: 1.264 ± 0.024	1.194HisGly: 1.194 ± 0.021	0.592HisHis: 0.592 ± 0.015	1.144HisIle: 1.144 ± 0.018	0.715HisLys: 0.715 ± 0.015	2.29HisLeu: 2.29 ± 0.034	0.326HisMet: 0.326 ± 0.01	0.734HisAsn: 0.734 ± 0.015	1.329HisPro: 1.329 ± 0.024	0.911HisGln: 0.911 ± 0.019	1.193HisArg: 1.193 ± 0.023	1.022HisSer: 1.022 ± 0.017	1.002HisThr: 1.002 ± 0.024	0.848HisVal: 0.848 ± 0.016	0.368HisTrp: 0.368 ± 0.011	0.971HisTyr: 0.971 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	4.856IleAla: 4.856 ± 0.044	0.666IleCys: 0.666 ± 0.021	4.187IleAsp: 4.187 ± 0.051	3.969IleGlu: 3.969 ± 0.044	2.822IlePhe: 2.822 ± 0.04	4.707IleGly: 4.707 ± 0.049	1.232IleHis: 1.232 ± 0.022	3.656IleIle: 3.656 ± 0.042	2.776IleLys: 2.776 ± 0.035	5.823IleLeu: 5.823 ± 0.048	1.112IleMet: 1.112 ± 0.018	3.039IleAsn: 3.039 ± 0.039	3.071IlePro: 3.071 ± 0.04	2.385IleGln: 2.385 ± 0.029	3.889IleArg: 3.889 ± 0.041	4.336IleSer: 4.336 ± 0.04	3.95IleThr: 3.95 ± 0.086	3.653IleVal: 3.653 ± 0.039	0.859IleTrp: 0.859 ± 0.019	2.318IleTyr: 2.318 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.673LysAla: 3.673 ± 0.048	0.264LysCys: 0.264 ± 0.01	2.783LysAsp: 2.783 ± 0.03	3.251LysGlu: 3.251 ± 0.042	1.668LysPhe: 1.668 ± 0.025	3.021LysGly: 3.021 ± 0.037	0.858LysHis: 0.858 ± 0.017	3.179LysIle: 3.179 ± 0.04	3.18LysLys: 3.18 ± 0.046	4.38LysLeu: 4.38 ± 0.052	1.336LysMet: 1.336 ± 0.024	2.268LysAsn: 2.268 ± 0.031	1.787LysPro: 1.787 ± 0.028	1.779LysGln: 1.779 ± 0.028	2.39LysArg: 2.39 ± 0.033	2.558LysSer: 2.558 ± 0.034	2.598LysThr: 2.598 ± 0.029	3.179LysVal: 3.179 ± 0.043	0.67LysTrp: 0.67 ± 0.016	1.775LysTyr: 1.775 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	7.686LeuAla: 7.686 ± 0.062	0.765LeuCys: 0.765 ± 0.019	5.961LeuAsp: 5.961 ± 0.049	6.959LeuGlu: 6.959 ± 0.058	4.585LeuPhe: 4.585 ± 0.046	6.354LeuGly: 6.354 ± 0.057	1.849LeuHis: 1.849 ± 0.029	6.123LeuIle: 6.123 ± 0.052	4.763LeuLys: 4.763 ± 0.053	10.395LeuLeu: 10.395 ± 0.1	1.94LeuMet: 1.94 ± 0.026	4.43LeuAsn: 4.43 ± 0.043	4.984LeuPro: 4.984 ± 0.047	4.383LeuGln: 4.383 ± 0.049	5.097LeuArg: 5.097 ± 0.051	6.942LeuSer: 6.942 ± 0.062	5.463LeuThr: 5.463 ± 0.054	5.704LeuVal: 5.704 ± 0.059	1.186LeuTrp: 1.186 ± 0.024	3.315LeuTyr: 3.315 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	1.786MetAla: 1.786 ± 0.025	0.115MetCys: 0.115 ± 0.006	1.391MetAsp: 1.391 ± 0.02	1.549MetGlu: 1.549 ± 0.023	0.621MetPhe: 0.621 ± 0.014	1.472MetGly: 1.472 ± 0.02	0.398MetHis: 0.398 ± 0.012	1.348MetIle: 1.348 ± 0.022	1.414MetLys: 1.414 ± 0.022	1.959MetLeu: 1.959 ± 0.027	0.523MetMet: 0.523 ± 0.014	0.993MetAsn: 0.993 ± 0.02	1.037MetPro: 1.037 ± 0.02	0.938MetGln: 0.938 ± 0.019	1.091MetArg: 1.091 ± 0.02	1.219MetSer: 1.219 ± 0.02	1.168MetThr: 1.168 ± 0.022	1.413MetVal: 1.413 ± 0.024	0.201MetTrp: 0.201 ± 0.008	0.597MetTyr: 0.597 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.186AsnAla: 3.186 ± 0.035	0.536AsnCys: 0.536 ± 0.022	2.593AsnAsp: 2.593 ± 0.047	2.521AsnGlu: 2.521 ± 0.034	2.308AsnPhe: 2.308 ± 0.031	4.078AsnGly: 4.078 ± 0.066	0.833AsnHis: 0.833 ± 0.015	2.94AsnIle: 2.94 ± 0.038	1.767AsnLys: 1.767 ± 0.026	4.311AsnLeu: 4.311 ± 0.047	0.907AsnMet: 0.907 ± 0.017	2.286AsnAsn: 2.286 ± 0.036	2.558AsnPro: 2.558 ± 0.034	1.822AsnGln: 1.822 ± 0.028	2.515AsnArg: 2.515 ± 0.034	2.619AsnSer: 2.619 ± 0.035	2.693AsnThr: 2.693 ± 0.041	2.549AsnVal: 2.549 ± 0.044	0.837AsnTrp: 0.837 ± 0.019	2.165AsnTyr: 2.165 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	3.923ProAla: 3.923 ± 0.046	0.281ProCys: 0.281 ± 0.014	3.675ProAsp: 3.675 ± 0.04	4.097ProGlu: 4.097 ± 0.045	2.03ProPhe: 2.03 ± 0.027	3.508ProGly: 3.508 ± 0.042	0.825ProHis: 0.825 ± 0.018	2.515ProIle: 2.515 ± 0.027	1.748ProLys: 1.748 ± 0.026	3.781ProLeu: 3.781 ± 0.041	0.837ProMet: 0.837 ± 0.017	2.238ProAsn: 2.238 ± 0.031	1.812ProPro: 1.812 ± 0.038	1.586ProGln: 1.586 ± 0.024	1.626ProArg: 1.626 ± 0.024	2.368ProSer: 2.368 ± 0.032	2.401ProThr: 2.401 ± 0.061	3.584ProVal: 3.584 ± 0.068	0.537ProTrp: 0.537 ± 0.015	1.619ProTyr: 1.619 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	3.168GlnAla: 3.168 ± 0.033	0.247GlnCys: 0.247 ± 0.01	2.288GlnAsp: 2.288 ± 0.041	2.895GlnGlu: 2.895 ± 0.04	1.84GlnPhe: 1.84 ± 0.024	2.373GlnGly: 2.373 ± 0.03	0.852GlnHis: 0.852 ± 0.017	2.604GlnIle: 2.604 ± 0.032	2.072GlnLys: 2.072 ± 0.029	4.862GlnLeu: 4.862 ± 0.049	1.002GlnMet: 1.002 ± 0.018	1.781GlnAsn: 1.781 ± 0.024	1.883GlnPro: 1.883 ± 0.025	2.207GlnGln: 2.207 ± 0.034	2.162GlnArg: 2.162 ± 0.032	2.353GlnSer: 2.353 ± 0.028	2.215GlnThr: 2.215 ± 0.045	2.602GlnVal: 2.602 ± 0.033	0.623GlnTrp: 0.623 ± 0.017	1.596GlnTyr: 1.596 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	3.543ArgAla: 3.543 ± 0.042	0.339ArgCys: 0.339 ± 0.011	2.888ArgAsp: 2.888 ± 0.037	3.784ArgGlu: 3.784 ± 0.043	2.635ArgPhe: 2.635 ± 0.032	3.01ArgGly: 3.01 ± 0.035	1.078ArgHis: 1.078 ± 0.021	3.793ArgIle: 3.793 ± 0.044	2.896ArgLys: 2.896 ± 0.038	5.275ArgLeu: 5.275 ± 0.058	1.37ArgMet: 1.37 ± 0.022	2.413ArgAsn: 2.413 ± 0.031	2.171ArgPro: 2.171 ± 0.029	2.462ArgGln: 2.462 ± 0.036	2.831ArgArg: 2.831 ± 0.036	3.318ArgSer: 3.318 ± 0.042	2.815ArgThr: 2.815 ± 0.035	2.97ArgVal: 2.97 ± 0.034	0.798ArgTrp: 0.798 ± 0.017	2.286ArgTyr: 2.286 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	4.315SerAla: 4.315 ± 0.041	0.748SerCys: 0.748 ± 0.021	3.601SerAsp: 3.601 ± 0.042	3.647SerGlu: 3.647 ± 0.036	3.167SerPhe: 3.167 ± 0.033	5.507SerGly: 5.507 ± 0.056	0.976SerHis: 0.976 ± 0.019	3.964SerIle: 3.964 ± 0.039	2.415SerLys: 2.415 ± 0.03	6.113SerLeu: 6.113 ± 0.054	1.271SerMet: 1.271 ± 0.021	2.607SerAsn: 2.607 ± 0.035	2.732SerPro: 2.732 ± 0.034	2.008SerGln: 2.008 ± 0.024	3.164SerArg: 3.164 ± 0.038	3.672SerSer: 3.672 ± 0.043	3.327SerThr: 3.327 ± 0.047	3.873SerVal: 3.873 ± 0.039	1.018SerTrp: 1.018 ± 0.022	2.337SerTyr: 2.337 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	4.809ThrAla: 4.809 ± 0.064	0.506ThrCys: 0.506 ± 0.027	3.922ThrAsp: 3.922 ± 0.078	3.392ThrGlu: 3.392 ± 0.039	2.881ThrPhe: 2.881 ± 0.044	4.775ThrGly: 4.775 ± 0.06	0.958ThrHis: 0.958 ± 0.018	4.024ThrIle: 4.024 ± 0.088	1.926ThrLys: 1.926 ± 0.029	5.264ThrLeu: 5.264 ± 0.046	0.876ThrMet: 0.876 ± 0.016	2.357ThrAsn: 2.357 ± 0.035	2.86ThrPro: 2.86 ± 0.043	1.855ThrGln: 1.855 ± 0.036	2.373ThrArg: 2.373 ± 0.032	3.201ThrSer: 3.201 ± 0.038	3.409ThrThr: 3.409 ± 0.072	4.325ThrVal: 4.325 ± 0.1	0.768ThrTrp: 0.768 ± 0.027	2.58ThrTyr: 2.58 ± 0.069	0.0ThrXaa: 0.0 ± 0.0
Val	4.583ValAla: 4.583 ± 0.04	0.56ValCys: 0.56 ± 0.017	4.036ValAsp: 4.036 ± 0.057	4.013ValGlu: 4.013 ± 0.044	2.927ValPhe: 2.927 ± 0.034	3.992ValGly: 3.992 ± 0.046	1.153ValHis: 1.153 ± 0.024	4.015ValIle: 4.015 ± 0.048	2.891ValLys: 2.891 ± 0.034	5.854ValLeu: 5.854 ± 0.051	1.305ValMet: 1.305 ± 0.023	2.936ValAsn: 2.936 ± 0.04	2.721ValPro: 2.721 ± 0.041	2.314ValGln: 2.314 ± 0.033	3.298ValArg: 3.298 ± 0.032	4.148ValSer: 4.148 ± 0.046	3.709ValThr: 3.709 ± 0.097	4.091ValVal: 4.091 ± 0.045	0.818ValTrp: 0.818 ± 0.017	2.302ValTyr: 2.302 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	0.894TrpAla: 0.894 ± 0.017	0.128TrpCys: 0.128 ± 0.007	0.895TrpAsp: 0.895 ± 0.019	1.018TrpGlu: 1.018 ± 0.018	0.587TrpPhe: 0.587 ± 0.017	0.992TrpGly: 0.992 ± 0.018	0.306TrpHis: 0.306 ± 0.01	0.88TrpIle: 0.88 ± 0.022	0.77TrpLys: 0.77 ± 0.018	1.425TrpLeu: 1.425 ± 0.027	0.424TrpMet: 0.424 ± 0.011	0.721TrpAsn: 0.721 ± 0.019	0.48TrpPro: 0.48 ± 0.015	0.742TrpGln: 0.742 ± 0.017	0.773TrpArg: 0.773 ± 0.018	0.954TrpSer: 0.954 ± 0.019	0.853TrpThr: 0.853 ± 0.025	0.859TrpVal: 0.859 ± 0.017	0.275TrpTrp: 0.275 ± 0.011	0.533TrpTyr: 0.533 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.637TyrAla: 2.637 ± 0.028	0.359TyrCys: 0.359 ± 0.011	2.448TyrAsp: 2.448 ± 0.028	2.391TyrGlu: 2.391 ± 0.032	2.173TyrPhe: 2.173 ± 0.029	2.706TyrGly: 2.706 ± 0.039	0.916TyrHis: 0.916 ± 0.02	1.901TyrIle: 1.901 ± 0.027	1.4TyrLys: 1.4 ± 0.021	4.111TyrLeu: 4.111 ± 0.043	0.597TyrMet: 0.597 ± 0.014	1.741TyrAsn: 1.741 ± 0.027	1.808TyrPro: 1.808 ± 0.023	1.987TyrGln: 1.987 ± 0.029	2.778TyrArg: 2.778 ± 0.039	2.341TyrSer: 2.341 ± 0.035	2.382TyrThr: 2.382 ± 0.054	2.047TyrVal: 2.047 ± 0.031	0.621TyrTrp: 0.621 ± 0.012	1.796TyrTyr: 1.796 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8179 proteins (3270642 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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