Human polyomavirus IPPyV

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Sepolyvirales; Polyomaviridae; Alphapolyomavirus; Human polyomavirus 9

Average proteome isoelectric point is 6.75

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|F8K9Y5|F8K9Y5_9POLY Minor capsid protein OS=Human polyomavirus IPPyV OX=988774 GN=VP2 PE=3 SV=1
MM1 pKa = 7.58APQRR5 pKa = 11.84KK6 pKa = 8.37RR7 pKa = 11.84QEE9 pKa = 4.25CGACPVKK16 pKa = 10.01KK17 pKa = 8.84TCPTPAPVPKK27 pKa = 10.17LLVKK31 pKa = 10.79GGVEE35 pKa = 3.97VLEE38 pKa = 4.41VRR40 pKa = 11.84TGPDD44 pKa = 3.47AITQIEE50 pKa = 4.77AYY52 pKa = 10.29LNPRR56 pKa = 11.84MGNNNPTDD64 pKa = 3.56EE65 pKa = 4.81LYY67 pKa = 10.8GYY69 pKa = 10.12SADD72 pKa = 3.72INVASSKK79 pKa = 11.19ASDD82 pKa = 3.82NPNATTLPTYY92 pKa = 10.42SVAVIKK98 pKa = 10.8LPMLNEE104 pKa = 4.7DD105 pKa = 3.88MTCDD109 pKa = 3.43TLLMWEE115 pKa = 4.21AVSVKK120 pKa = 9.54TEE122 pKa = 3.61VMGISSLVNLHH133 pKa = 6.16QGGKK137 pKa = 9.56YY138 pKa = 9.87IYY140 pKa = 9.16GSSSGTIPVQGTTLHH155 pKa = 5.8MFSVGGEE162 pKa = 3.93PLEE165 pKa = 4.14LQGLVASSTTTYY177 pKa = 8.0PTDD180 pKa = 3.08MVTIKK185 pKa = 10.75NMKK188 pKa = 9.15PVNQALDD195 pKa = 3.93PNAKK199 pKa = 10.22ALLDD203 pKa = 3.78KK204 pKa = 10.92DD205 pKa = 3.32GKK207 pKa = 11.03YY208 pKa = 9.73PVEE211 pKa = 4.23VWSPDD216 pKa = 3.11PSKK219 pKa = 11.54NEE221 pKa = 3.36NTRR224 pKa = 11.84YY225 pKa = 10.01YY226 pKa = 11.35GSFTGGATTPPVMQFTNSVTTVLLDD251 pKa = 3.75EE252 pKa = 5.12NGVGPLCKK260 pKa = 9.66GDD262 pKa = 4.21KK263 pKa = 10.6LFLSAVDD270 pKa = 3.06IVGIHH275 pKa = 5.43TNYY278 pKa = 10.25SEE280 pKa = 4.2SQNWRR285 pKa = 11.84GLPRR289 pKa = 11.84YY290 pKa = 9.93FNVTLRR296 pKa = 11.84KK297 pKa = 9.25RR298 pKa = 11.84VVKK301 pKa = 10.6NPYY304 pKa = 9.06PVSSLLNSLFSGLMPQIQGQPMEE327 pKa = 4.48GTSGQVEE334 pKa = 4.43EE335 pKa = 4.02VRR337 pKa = 11.84IYY339 pKa = 10.71QGTEE343 pKa = 3.76GLPGDD348 pKa = 4.76PDD350 pKa = 3.8LDD352 pKa = 3.64RR353 pKa = 11.84YY354 pKa = 9.92VDD356 pKa = 4.37KK357 pKa = 10.98FCQNQTVPPRR367 pKa = 11.84SNDD370 pKa = 3.19QQ371 pKa = 3.14

Molecular weight: 40.33 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|F8K9Y6|F8K9Y6_9POLY Minor capsid protein OS=Human polyomavirus IPPyV OX=988774 GN=VP3 PE=3 SV=1
MM1 pKa = 7.7ALTPWFPQVDD11 pKa = 4.05YY12 pKa = 10.83LFPGLSSFSYY22 pKa = 10.36YY23 pKa = 10.81LNAALDD29 pKa = 3.48WGEE32 pKa = 4.4SLFHH36 pKa = 6.55AVGRR40 pKa = 11.84EE41 pKa = 3.21IWRR44 pKa = 11.84NIMRR48 pKa = 11.84QATQQIGYY56 pKa = 6.48TSRR59 pKa = 11.84ALAVRR64 pKa = 11.84GTNEE68 pKa = 4.05FQHH71 pKa = 6.21MLAQIAEE78 pKa = 4.27NARR81 pKa = 11.84WALTNGPIHH90 pKa = 7.04IYY92 pKa = 10.57SSVEE96 pKa = 3.49EE97 pKa = 4.47YY98 pKa = 11.07YY99 pKa = 10.71RR100 pKa = 11.84GLPSVNPIQLRR111 pKa = 11.84QQYY114 pKa = 9.51RR115 pKa = 11.84SRR117 pKa = 11.84GEE119 pKa = 3.83LPPTRR124 pKa = 11.84EE125 pKa = 3.5QFEE128 pKa = 4.27YY129 pKa = 10.75QEE131 pKa = 4.2QVRR134 pKa = 11.84LRR136 pKa = 11.84RR137 pKa = 11.84EE138 pKa = 3.78IGGSEE143 pKa = 4.21PRR145 pKa = 11.84SGHH148 pKa = 4.96YY149 pKa = 8.33VQHH152 pKa = 6.1YY153 pKa = 7.59AAPGGANQRR162 pKa = 11.84VSQDD166 pKa = 2.31WMLPLILGLYY176 pKa = 10.53GDD178 pKa = 4.72ITPTWEE184 pKa = 4.07KK185 pKa = 10.67EE186 pKa = 3.76LSKK189 pKa = 11.1LEE191 pKa = 4.0KK192 pKa = 10.47EE193 pKa = 4.58EE194 pKa = 3.92YY195 pKa = 10.71GPPKK199 pKa = 9.92KK200 pKa = 9.98KK201 pKa = 10.6ARR203 pKa = 11.84VRR205 pKa = 11.84SMSCKK210 pKa = 10.1KK211 pKa = 10.27NLSNTRR217 pKa = 11.84SRR219 pKa = 11.84SQTPCQRR226 pKa = 11.84RR227 pKa = 11.84GRR229 pKa = 11.84SSRR232 pKa = 11.84SS233 pKa = 3.16

Molecular weight: 26.94 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

1825

189

680

365.0

41.27

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.589 ± 1.142

2.137 ± 0.589

3.945 ± 0.763

6.849 ± 0.547

3.945 ± 0.726

6.63 ± 0.857

1.918 ± 0.471

4.712 ± 0.473

6.192 ± 1.393

10.466 ± 0.633

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.301 ± 0.284

4.822 ± 0.511

5.699 ± 0.745

5.096 ± 0.376

4.822 ± 1.179

7.671 ± 0.335

5.753 ± 0.707

5.589 ± 0.875

1.808 ± 0.346

4.055 ± 0.273
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski