Amino acid dipepetide frequency for Beihai picorna-like virus 28

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.006AlaAla: 5.006 ± 0.022
1.54AlaCys: 1.54 ± 0.838
3.851AlaAsp: 3.851 ± 1.282
7.316AlaGlu: 7.316 ± 2.628
3.851AlaPhe: 3.851 ± 0.606
6.161AlaGly: 6.161 ± 0.7
1.54AlaHis: 1.54 ± 0.838
3.08AlaIle: 3.08 ± 0.325
3.466AlaLys: 3.466 ± 1.885
5.006AlaLeu: 5.006 ± 0.697
1.925AlaMet: 1.925 ± 0.303
3.08AlaAsn: 3.08 ± 0.325
5.006AlaPro: 5.006 ± 1.328
1.54AlaGln: 1.54 ± 0.838
5.006AlaArg: 5.006 ± 2.047
4.621AlaSer: 4.621 ± 0.863
4.236AlaThr: 4.236 ± 1.747
5.006AlaVal: 5.006 ± 0.697
1.155AlaTrp: 1.155 ± 0.047
3.466AlaTyr: 3.466 ± 0.141
0.0AlaXaa: 0.0 ± 0.0
Cys
1.925CysAla: 1.925 ± 0.372
0.77CysCys: 0.77 ± 0.419
0.385CysAsp: 0.385 ± 0.209
0.77CysGlu: 0.77 ± 0.419
0.77CysPhe: 0.77 ± 0.419
1.54CysGly: 1.54 ± 0.838
0.0CysHis: 0.0 ± 0.0
0.385CysIle: 0.385 ± 0.209
0.77CysLys: 0.77 ± 0.419
1.54CysLeu: 1.54 ± 0.838
0.385CysMet: 0.385 ± 0.209
0.77CysAsn: 0.77 ± 0.419
1.54CysPro: 1.54 ± 0.838
0.77CysGln: 0.77 ± 0.256
1.155CysArg: 1.155 ± 0.047
0.0CysSer: 0.0 ± 0.0
1.54CysThr: 1.54 ± 0.838
1.155CysVal: 1.155 ± 0.628
0.0CysTrp: 0.0 ± 0.0
0.77CysTyr: 0.77 ± 0.419
0.0CysXaa: 0.0 ± 0.0
Asp
5.391AspAla: 5.391 ± 0.231
0.385AspCys: 0.385 ± 0.209
1.925AspAsp: 1.925 ± 0.372
3.851AspGlu: 3.851 ± 0.069
6.161AspPhe: 6.161 ± 0.7
2.31AspGly: 2.31 ± 1.256
1.54AspHis: 1.54 ± 0.838
2.31AspIle: 2.31 ± 0.769
2.695AspLys: 2.695 ± 0.791
3.851AspLeu: 3.851 ± 0.744
1.155AspMet: 1.155 ± 0.047
3.851AspAsn: 3.851 ± 1.957
4.621AspPro: 4.621 ± 2.888
2.695AspGln: 2.695 ± 0.56
1.54AspArg: 1.54 ± 0.162
0.77AspSer: 0.77 ± 0.419
3.466AspThr: 3.466 ± 1.491
3.466AspVal: 3.466 ± 0.816
1.54AspTrp: 1.54 ± 0.162
2.695AspTyr: 2.695 ± 0.791
0.0AspXaa: 0.0 ± 0.0
Glu
3.466GluAla: 3.466 ± 1.885
1.54GluCys: 1.54 ± 0.838
4.621GluAsp: 4.621 ± 0.863
3.851GluGlu: 3.851 ± 2.094
4.621GluPhe: 4.621 ± 0.487
1.925GluGly: 1.925 ± 1.047
3.08GluHis: 3.08 ± 1.0
1.925GluIle: 1.925 ± 0.303
2.695GluLys: 2.695 ± 1.466
6.546GluLeu: 6.546 ± 1.166
1.925GluMet: 1.925 ± 0.372
2.31GluAsn: 2.31 ± 0.581
2.31GluPro: 2.31 ± 0.581
1.54GluGln: 1.54 ± 0.162
3.466GluArg: 3.466 ± 1.209
5.776GluSer: 5.776 ± 0.44
3.466GluThr: 3.466 ± 1.209
3.851GluVal: 3.851 ± 2.632
1.155GluTrp: 1.155 ± 0.047
3.466GluTyr: 3.466 ± 0.534
0.0GluXaa: 0.0 ± 0.0
Phe
4.236PheAla: 4.236 ± 0.953
0.385PheCys: 0.385 ± 0.209
3.08PheAsp: 3.08 ± 1.0
5.391PheGlu: 5.391 ± 1.119
3.08PhePhe: 3.08 ± 1.0
3.466PheGly: 3.466 ± 0.141
1.925PheHis: 1.925 ± 0.303
1.54PheIle: 1.54 ± 0.838
2.695PheLys: 2.695 ± 0.791
1.925PheLeu: 1.925 ± 0.372
2.31PheMet: 2.31 ± 0.094
1.925PheAsn: 1.925 ± 1.653
4.236PhePro: 4.236 ± 0.397
1.925PheGln: 1.925 ± 0.372
3.08PheArg: 3.08 ± 1.025
3.851PheSer: 3.851 ± 1.957
3.466PheThr: 3.466 ± 0.141
3.466PheVal: 3.466 ± 0.141
0.385PheTrp: 0.385 ± 0.466
1.54PheTyr: 1.54 ± 0.162
0.0PheXaa: 0.0 ± 0.0
Gly
2.31GlyAla: 2.31 ± 1.444
0.385GlyCys: 0.385 ± 0.209
2.31GlyAsp: 2.31 ± 0.094
3.851GlyGlu: 3.851 ± 0.069
2.31GlyPhe: 2.31 ± 0.581
3.08GlyGly: 3.08 ± 1.025
0.385GlyHis: 0.385 ± 0.209
5.006GlyIle: 5.006 ± 0.022
3.851GlyLys: 3.851 ± 0.744
6.161GlyLeu: 6.161 ± 2.0
1.155GlyMet: 1.155 ± 0.628
2.31GlyAsn: 2.31 ± 1.444
3.08GlyPro: 3.08 ± 1.7
2.31GlyGln: 2.31 ± 0.094
3.466GlyArg: 3.466 ± 0.816
5.776GlySer: 5.776 ± 0.235
2.31GlyThr: 2.31 ± 0.581
2.695GlyVal: 2.695 ± 0.116
0.0GlyTrp: 0.0 ± 0.0
1.54GlyTyr: 1.54 ± 0.513
0.0GlyXaa: 0.0 ± 0.0
His
1.54HisAla: 1.54 ± 0.838
0.77HisCys: 0.77 ± 0.419
0.385HisAsp: 0.385 ± 0.209
1.155HisGlu: 1.155 ± 0.047
0.77HisPhe: 0.77 ± 0.419
1.925HisGly: 1.925 ± 1.047
0.77HisHis: 0.77 ± 0.419
1.155HisIle: 1.155 ± 0.628
1.155HisLys: 1.155 ± 0.047
2.695HisLeu: 2.695 ± 0.116
0.77HisMet: 0.77 ± 0.419
1.155HisAsn: 1.155 ± 0.722
1.155HisPro: 1.155 ± 0.628
0.77HisGln: 0.77 ± 0.419
0.77HisArg: 0.77 ± 0.419
2.695HisSer: 2.695 ± 0.56
0.385HisThr: 0.385 ± 0.209
0.77HisVal: 0.77 ± 0.256
0.0HisTrp: 0.0 ± 0.0
1.155HisTyr: 1.155 ± 0.628
0.0HisXaa: 0.0 ± 0.0
Ile
4.236IleAla: 4.236 ± 0.278
1.155IleCys: 1.155 ± 0.628
2.695IleAsp: 2.695 ± 1.91
2.31IleGlu: 2.31 ± 0.581
1.54IlePhe: 1.54 ± 0.838
3.851IleGly: 3.851 ± 0.069
1.925IleHis: 1.925 ± 0.303
2.31IleIle: 2.31 ± 0.581
1.925IleLys: 1.925 ± 0.303
2.31IleLeu: 2.31 ± 0.581
1.155IleMet: 1.155 ± 0.047
2.695IleAsn: 2.695 ± 0.116
2.695IlePro: 2.695 ± 0.56
1.155IleGln: 1.155 ± 0.628
3.851IleArg: 3.851 ± 0.606
4.236IleSer: 4.236 ± 1.628
5.776IleThr: 5.776 ± 0.91
2.695IleVal: 2.695 ± 0.116
0.0IleTrp: 0.0 ± 0.0
1.925IleTyr: 1.925 ± 0.978
0.0IleXaa: 0.0 ± 0.0
Lys
3.466LysAla: 3.466 ± 1.209
0.77LysCys: 0.77 ± 0.419
4.236LysAsp: 4.236 ± 2.303
3.851LysGlu: 3.851 ± 1.419
3.851LysPhe: 3.851 ± 0.069
3.851LysGly: 3.851 ± 0.744
0.77LysHis: 0.77 ± 0.256
3.08LysIle: 3.08 ± 1.025
1.925LysLys: 1.925 ± 0.303
3.851LysLeu: 3.851 ± 0.744
1.54LysMet: 1.54 ± 0.748
2.31LysAsn: 2.31 ± 0.581
1.155LysPro: 1.155 ± 0.722
1.155LysGln: 1.155 ± 0.047
6.546LysArg: 6.546 ± 2.209
5.006LysSer: 5.006 ± 2.722
3.08LysThr: 3.08 ± 0.35
4.621LysVal: 4.621 ± 1.163
0.385LysTrp: 0.385 ± 0.209
2.695LysTyr: 2.695 ± 1.466
0.0LysXaa: 0.0 ± 0.0
Leu
8.086LeuAla: 8.086 ± 0.347
1.54LeuCys: 1.54 ± 0.838
3.851LeuAsp: 3.851 ± 0.069
2.31LeuGlu: 2.31 ± 0.094
2.695LeuPhe: 2.695 ± 0.116
3.08LeuGly: 3.08 ± 1.7
1.54LeuHis: 1.54 ± 0.838
5.006LeuIle: 5.006 ± 0.697
4.236LeuLys: 4.236 ± 0.953
6.546LeuLeu: 6.546 ± 2.209
3.466LeuMet: 3.466 ± 0.534
5.391LeuAsn: 5.391 ± 0.444
4.621LeuPro: 4.621 ± 0.863
2.695LeuGln: 2.695 ± 0.56
3.851LeuArg: 3.851 ± 0.606
6.546LeuSer: 6.546 ± 0.184
7.316LeuThr: 7.316 ± 2.773
3.851LeuVal: 3.851 ± 0.744
0.77LeuTrp: 0.77 ± 0.419
4.621LeuTyr: 4.621 ± 0.188
0.0LeuXaa: 0.0 ± 0.0
Met
3.466MetAla: 3.466 ± 0.141
1.54MetCys: 1.54 ± 0.162
1.155MetAsp: 1.155 ± 0.047
0.77MetGlu: 0.77 ± 0.419
1.54MetPhe: 1.54 ± 1.863
0.77MetGly: 0.77 ± 0.419
0.0MetHis: 0.0 ± 0.0
2.695MetIle: 2.695 ± 0.791
1.155MetLys: 1.155 ± 0.047
1.155MetLeu: 1.155 ± 0.047
0.385MetMet: 0.385 ± 0.209
0.77MetAsn: 0.77 ± 0.931
1.54MetPro: 1.54 ± 0.838
1.925MetGln: 1.925 ± 0.372
0.77MetArg: 0.77 ± 0.419
4.236MetSer: 4.236 ± 0.953
0.77MetThr: 0.77 ± 0.256
1.155MetVal: 1.155 ± 0.628
0.385MetTrp: 0.385 ± 0.209
1.925MetTyr: 1.925 ± 0.303
0.0MetXaa: 0.0 ± 0.0
Asn
5.391AsnAla: 5.391 ± 0.444
0.385AsnCys: 0.385 ± 0.209
1.155AsnAsp: 1.155 ± 0.047
1.54AsnGlu: 1.54 ± 0.162
3.851AsnPhe: 3.851 ± 0.069
4.236AsnGly: 4.236 ± 0.397
0.77AsnHis: 0.77 ± 0.419
2.695AsnIle: 2.695 ± 1.235
3.08AsnLys: 3.08 ± 0.35
5.391AsnLeu: 5.391 ± 0.231
0.385AsnMet: 0.385 ± 0.209
1.54AsnAsn: 1.54 ± 0.162
5.006AsnPro: 5.006 ± 2.679
0.77AsnGln: 0.77 ± 0.256
1.155AsnArg: 1.155 ± 0.722
2.695AsnSer: 2.695 ± 0.791
2.695AsnThr: 2.695 ± 3.26
3.08AsnVal: 3.08 ± 0.325
0.385AsnTrp: 0.385 ± 0.466
1.54AsnTyr: 1.54 ± 0.513
0.0AsnXaa: 0.0 ± 0.0
Pro
4.621ProAla: 4.621 ± 0.188
0.0ProCys: 0.0 ± 0.0
4.236ProAsp: 4.236 ± 1.072
3.08ProGlu: 3.08 ± 0.325
2.31ProPhe: 2.31 ± 0.769
1.925ProGly: 1.925 ± 0.303
1.155ProHis: 1.155 ± 0.628
2.695ProIle: 2.695 ± 1.235
3.851ProLys: 3.851 ± 1.419
3.851ProLeu: 3.851 ± 1.957
1.155ProMet: 1.155 ± 0.967
1.925ProAsn: 1.925 ± 0.978
1.925ProPro: 1.925 ± 0.303
1.54ProGln: 1.54 ± 0.513
2.31ProArg: 2.31 ± 1.256
3.466ProSer: 3.466 ± 2.166
4.236ProThr: 4.236 ± 0.397
5.006ProVal: 5.006 ± 2.679
1.155ProTrp: 1.155 ± 0.722
3.08ProTyr: 3.08 ± 1.025
0.0ProXaa: 0.0 ± 0.0
Gln
2.31GlnAla: 2.31 ± 1.256
0.77GlnCys: 0.77 ± 0.419
1.155GlnAsp: 1.155 ± 0.722
2.31GlnGlu: 2.31 ± 0.581
1.155GlnPhe: 1.155 ± 0.628
0.77GlnGly: 0.77 ± 0.256
0.77GlnHis: 0.77 ± 0.419
1.925GlnIle: 1.925 ± 0.303
3.851GlnLys: 3.851 ± 0.744
3.851GlnLeu: 3.851 ± 0.744
0.77GlnMet: 0.77 ± 0.256
0.77GlnAsn: 0.77 ± 0.256
1.155GlnPro: 1.155 ± 0.722
0.77GlnGln: 0.77 ± 0.256
1.54GlnArg: 1.54 ± 0.513
0.385GlnSer: 0.385 ± 0.466
1.155GlnThr: 1.155 ± 0.047
1.155GlnVal: 1.155 ± 0.722
1.155GlnTrp: 1.155 ± 0.047
2.31GlnTyr: 2.31 ± 0.581
0.0GlnXaa: 0.0 ± 0.0
Arg
4.621ArgAla: 4.621 ± 0.188
0.385ArgCys: 0.385 ± 0.209
3.466ArgAsp: 3.466 ± 0.534
4.621ArgGlu: 4.621 ± 1.163
2.31ArgPhe: 2.31 ± 0.769
3.851ArgGly: 3.851 ± 1.282
1.925ArgHis: 1.925 ± 0.372
2.31ArgIle: 2.31 ± 0.094
7.316ArgLys: 7.316 ± 2.628
5.391ArgLeu: 5.391 ± 0.906
2.31ArgMet: 2.31 ± 1.256
1.155ArgAsn: 1.155 ± 0.047
2.31ArgPro: 2.31 ± 1.444
1.54ArgGln: 1.54 ± 0.838
2.695ArgArg: 2.695 ± 0.56
2.695ArgSer: 2.695 ± 0.56
1.54ArgThr: 1.54 ± 0.162
3.08ArgVal: 3.08 ± 0.325
1.155ArgTrp: 1.155 ± 0.047
1.155ArgTyr: 1.155 ± 0.047
0.0ArgXaa: 0.0 ± 0.0
Ser
5.006SerAla: 5.006 ± 1.372
0.0SerCys: 0.0 ± 0.0
5.391SerAsp: 5.391 ± 0.906
4.236SerGlu: 4.236 ± 0.278
3.466SerPhe: 3.466 ± 0.534
3.851SerGly: 3.851 ± 0.069
1.155SerHis: 1.155 ± 0.722
4.621SerIle: 4.621 ± 1.163
3.466SerLys: 3.466 ± 0.141
6.931SerLeu: 6.931 ± 2.982
1.925SerMet: 1.925 ± 0.303
4.621SerAsn: 4.621 ± 0.487
3.466SerPro: 3.466 ± 0.141
2.31SerGln: 2.31 ± 0.094
3.851SerArg: 3.851 ± 0.069
8.086SerSer: 8.086 ± 1.679
4.621SerThr: 4.621 ± 1.538
3.466SerVal: 3.466 ± 0.534
0.77SerTrp: 0.77 ± 0.256
2.31SerTyr: 2.31 ± 0.094
0.0SerXaa: 0.0 ± 0.0
Thr
3.466ThrAla: 3.466 ± 1.491
1.155ThrCys: 1.155 ± 0.628
5.006ThrAsp: 5.006 ± 2.004
3.466ThrGlu: 3.466 ± 0.816
1.54ThrPhe: 1.54 ± 0.513
1.54ThrGly: 1.54 ± 0.162
0.385ThrHis: 0.385 ± 0.209
2.31ThrIle: 2.31 ± 1.444
4.236ThrLys: 4.236 ± 2.303
5.391ThrLeu: 5.391 ± 1.119
1.925ThrMet: 1.925 ± 0.978
3.851ThrAsn: 3.851 ± 0.069
3.466ThrPro: 3.466 ± 2.166
2.31ThrGln: 2.31 ± 1.444
3.08ThrArg: 3.08 ± 0.35
4.621ThrSer: 4.621 ± 0.188
3.466ThrThr: 3.466 ± 2.841
6.161ThrVal: 6.161 ± 2.726
2.31ThrTrp: 2.31 ± 0.581
1.155ThrTyr: 1.155 ± 0.047
0.0ThrXaa: 0.0 ± 0.0
Val
4.236ValAla: 4.236 ± 0.397
1.925ValCys: 1.925 ± 0.372
5.006ValAsp: 5.006 ± 0.022
5.391ValGlu: 5.391 ± 0.444
4.621ValPhe: 4.621 ± 0.863
2.695ValGly: 2.695 ± 1.235
0.77ValHis: 0.77 ± 0.419
1.54ValIle: 1.54 ± 0.838
2.695ValLys: 2.695 ± 0.116
5.391ValLeu: 5.391 ± 1.794
1.54ValMet: 1.54 ± 0.162
5.391ValAsn: 5.391 ± 1.794
2.31ValPro: 2.31 ± 0.581
0.385ValGln: 0.385 ± 0.209
4.236ValArg: 4.236 ± 0.953
3.08ValSer: 3.08 ± 0.35
3.466ValThr: 3.466 ± 1.491
3.08ValVal: 3.08 ± 1.0
0.77ValTrp: 0.77 ± 0.419
2.695ValTyr: 2.695 ± 0.116
0.0ValXaa: 0.0 ± 0.0
Trp
0.77TrpAla: 0.77 ± 0.419
0.385TrpCys: 0.385 ± 0.209
0.385TrpAsp: 0.385 ± 0.466
1.155TrpGlu: 1.155 ± 0.628
0.77TrpPhe: 0.77 ± 0.931
0.385TrpGly: 0.385 ± 0.209
0.0TrpHis: 0.0 ± 0.0
0.385TrpIle: 0.385 ± 0.209
1.155TrpLys: 1.155 ± 0.722
2.31TrpLeu: 2.31 ± 0.581
1.155TrpMet: 1.155 ± 0.628
0.385TrpAsn: 0.385 ± 0.209
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.155TrpArg: 1.155 ± 0.047
0.77TrpSer: 0.77 ± 0.931
1.925TrpThr: 1.925 ± 0.303
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.77TrpTyr: 0.77 ± 0.419
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.31TyrAla: 2.31 ± 0.769
1.155TyrCys: 1.155 ± 0.047
1.925TyrAsp: 1.925 ± 0.303
2.31TyrGlu: 2.31 ± 0.581
2.695TyrPhe: 2.695 ± 0.116
3.08TyrGly: 3.08 ± 1.025
1.54TyrHis: 1.54 ± 0.162
3.466TyrIle: 3.466 ± 0.534
1.925TyrLys: 1.925 ± 1.047
1.925TyrLeu: 1.925 ± 0.978
0.385TyrMet: 0.385 ± 0.466
1.54TyrAsn: 1.54 ± 0.513
2.31TyrPro: 2.31 ± 0.581
1.925TyrGln: 1.925 ± 1.047
2.31TyrArg: 2.31 ± 0.094
4.236TyrSer: 4.236 ± 0.278
1.925TyrThr: 1.925 ± 0.372
3.466TyrVal: 3.466 ± 0.534
0.385TyrTrp: 0.385 ± 0.209
1.155TyrTyr: 1.155 ± 0.722
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2598 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski