Amino acid dipepetide frequency for Fikirini rhabdovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.781AlaAla: 2.781 ± 1.574
1.669AlaCys: 1.669 ± 0.624
2.781AlaAsp: 2.781 ± 0.64
3.615AlaGlu: 3.615 ± 1.551
2.503AlaPhe: 2.503 ± 0.902
2.225AlaGly: 2.225 ± 0.471
1.947AlaHis: 1.947 ± 1.071
3.059AlaIle: 3.059 ± 0.865
2.225AlaLys: 2.225 ± 1.69
4.727AlaLeu: 4.727 ± 1.109
0.834AlaMet: 0.834 ± 0.431
1.669AlaAsn: 1.669 ± 0.405
1.947AlaPro: 1.947 ± 1.659
1.947AlaGln: 1.947 ± 1.844
3.615AlaArg: 3.615 ± 0.303
2.225AlaSer: 2.225 ± 0.807
1.947AlaThr: 1.947 ± 0.648
3.059AlaVal: 3.059 ± 0.665
1.112AlaTrp: 1.112 ± 0.381
2.503AlaTyr: 2.503 ± 0.908
0.0AlaXaa: 0.0 ± 0.0
Cys
0.278CysAla: 0.278 ± 0.153
0.278CysCys: 0.278 ± 0.153
0.278CysAsp: 0.278 ± 0.153
1.669CysGlu: 1.669 ± 0.602
0.556CysPhe: 0.556 ± 0.35
1.669CysGly: 1.669 ± 0.56
0.556CysHis: 0.556 ± 0.535
1.112CysIle: 1.112 ± 0.363
1.112CysLys: 1.112 ± 0.966
2.503CysLeu: 2.503 ± 0.784
0.278CysMet: 0.278 ± 0.473
0.834CysAsn: 0.834 ± 0.459
1.669CysPro: 1.669 ± 1.287
0.278CysGln: 0.278 ± 0.153
0.834CysArg: 0.834 ± 0.459
2.781CysSer: 2.781 ± 0.265
0.834CysThr: 0.834 ± 0.394
0.834CysVal: 0.834 ± 0.464
0.834CysTrp: 0.834 ± 0.459
2.225CysTyr: 2.225 ± 0.654
0.0CysXaa: 0.0 ± 0.0
Asp
1.669AspAla: 1.669 ± 0.746
1.947AspCys: 1.947 ± 1.035
2.503AspAsp: 2.503 ± 0.803
4.171AspGlu: 4.171 ± 2.172
1.947AspPhe: 1.947 ± 1.071
3.615AspGly: 3.615 ± 0.696
1.947AspHis: 1.947 ± 0.51
2.781AspIle: 2.781 ± 1.178
1.669AspLys: 1.669 ± 0.507
6.118AspLeu: 6.118 ± 2.257
1.947AspMet: 1.947 ± 0.263
1.669AspAsn: 1.669 ± 0.685
3.337AspPro: 3.337 ± 1.156
3.059AspGln: 3.059 ± 1.282
3.893AspArg: 3.893 ± 0.897
4.171AspSer: 4.171 ± 1.667
2.503AspThr: 2.503 ± 1.261
3.059AspVal: 3.059 ± 0.616
0.834AspTrp: 0.834 ± 0.28
3.615AspTyr: 3.615 ± 0.947
0.0AspXaa: 0.0 ± 0.0
Glu
3.059GluAla: 3.059 ± 1.918
1.947GluCys: 1.947 ± 0.988
3.893GluAsp: 3.893 ± 0.566
5.562GluGlu: 5.562 ± 2.667
1.947GluPhe: 1.947 ± 0.67
3.059GluGly: 3.059 ± 1.122
1.669GluHis: 1.669 ± 0.405
5.006GluIle: 5.006 ± 1.274
4.727GluLys: 4.727 ± 1.97
6.952GluLeu: 6.952 ± 2.008
1.112GluMet: 1.112 ± 0.484
1.947GluAsn: 1.947 ± 0.51
1.947GluPro: 1.947 ± 0.735
1.39GluGln: 1.39 ± 0.498
3.337GluArg: 3.337 ± 1.732
4.727GluSer: 4.727 ± 0.945
4.449GluThr: 4.449 ± 1.239
5.006GluVal: 5.006 ± 1.162
1.39GluTrp: 1.39 ± 1.216
2.503GluTyr: 2.503 ± 0.751
0.0GluXaa: 0.0 ± 0.0
Phe
1.39PheAla: 1.39 ± 0.437
1.39PheCys: 1.39 ± 0.498
3.059PheAsp: 3.059 ± 1.032
2.781PheGlu: 2.781 ± 1.523
1.669PhePhe: 1.669 ± 0.472
1.669PheGly: 1.669 ± 0.507
0.278PheHis: 0.278 ± 0.153
1.112PheIle: 1.112 ± 0.381
2.781PheLys: 2.781 ± 0.883
6.118PheLeu: 6.118 ± 2.063
1.112PheMet: 1.112 ± 0.403
2.225PheAsn: 2.225 ± 0.516
2.225PhePro: 2.225 ± 0.937
1.947PheGln: 1.947 ± 0.75
1.39PheArg: 1.39 ± 0.503
3.059PheSer: 3.059 ± 1.371
1.112PheThr: 1.112 ± 0.381
1.112PheVal: 1.112 ± 0.612
0.278PheTrp: 0.278 ± 0.153
2.225PheTyr: 2.225 ± 1.255
0.0PheXaa: 0.0 ± 0.0
Gly
1.947GlyAla: 1.947 ± 0.502
0.0GlyCys: 0.0 ± 0.0
3.615GlyAsp: 3.615 ± 1.024
3.059GlyGlu: 3.059 ± 0.918
2.503GlyPhe: 2.503 ± 0.697
3.059GlyGly: 3.059 ± 1.682
1.669GlyHis: 1.669 ± 0.33
3.615GlyIle: 3.615 ± 1.018
3.059GlyLys: 3.059 ± 0.347
8.065GlyLeu: 8.065 ± 1.306
1.669GlyMet: 1.669 ± 0.664
1.669GlyAsn: 1.669 ± 0.472
3.059GlyPro: 3.059 ± 0.662
1.669GlyGln: 1.669 ± 0.634
3.615GlyArg: 3.615 ± 1.436
5.006GlySer: 5.006 ± 0.928
4.171GlyThr: 4.171 ± 2.061
3.059GlyVal: 3.059 ± 0.844
0.556GlyTrp: 0.556 ± 0.306
1.39GlyTyr: 1.39 ± 0.508
0.0GlyXaa: 0.0 ± 0.0
His
1.39HisAla: 1.39 ± 0.437
0.556HisCys: 0.556 ± 0.306
0.834HisAsp: 0.834 ± 0.465
2.503HisGlu: 2.503 ± 0.75
0.834HisPhe: 0.834 ± 0.459
0.834HisGly: 0.834 ± 0.346
1.112HisHis: 1.112 ± 0.381
1.669HisIle: 1.669 ± 0.671
1.669HisLys: 1.669 ± 0.405
4.171HisLeu: 4.171 ± 1.321
0.0HisMet: 0.0 ± 0.0
0.834HisAsn: 0.834 ± 0.459
2.781HisPro: 2.781 ± 0.72
1.112HisGln: 1.112 ± 0.403
0.834HisArg: 0.834 ± 0.459
1.669HisSer: 1.669 ± 0.594
1.39HisThr: 1.39 ± 0.498
2.503HisVal: 2.503 ± 0.889
0.556HisTrp: 0.556 ± 0.306
0.278HisTyr: 0.278 ± 0.153
0.0HisXaa: 0.0 ± 0.0
Ile
2.781IleAla: 2.781 ± 0.866
1.112IleCys: 1.112 ± 0.403
3.893IleAsp: 3.893 ± 1.512
3.059IleGlu: 3.059 ± 0.842
1.947IlePhe: 1.947 ± 0.695
3.893IleGly: 3.893 ± 0.371
0.556IleHis: 0.556 ± 0.306
3.893IleIle: 3.893 ± 1.071
5.006IleLys: 5.006 ± 2.059
6.674IleLeu: 6.674 ± 0.976
1.39IleMet: 1.39 ± 0.505
3.059IleAsn: 3.059 ± 1.117
3.893IlePro: 3.893 ± 1.217
1.947IleGln: 1.947 ± 0.447
4.171IleArg: 4.171 ± 0.875
3.059IleSer: 3.059 ± 0.628
2.503IleThr: 2.503 ± 0.611
3.059IleVal: 3.059 ± 0.744
1.112IleTrp: 1.112 ± 0.453
1.669IleTyr: 1.669 ± 0.647
0.0IleXaa: 0.0 ± 0.0
Lys
2.225LysAla: 2.225 ± 1.301
1.112LysCys: 1.112 ± 0.966
4.171LysAsp: 4.171 ± 1.596
5.006LysGlu: 5.006 ± 2.531
1.39LysPhe: 1.39 ± 0.353
3.893LysGly: 3.893 ± 0.835
1.669LysHis: 1.669 ± 0.624
3.893LysIle: 3.893 ± 0.388
3.337LysLys: 3.337 ± 0.879
6.952LysLeu: 6.952 ± 2.011
1.669LysMet: 1.669 ± 0.405
3.337LysAsn: 3.337 ± 1.675
3.893LysPro: 3.893 ± 1.262
0.556LysGln: 0.556 ± 0.306
4.727LysArg: 4.727 ± 0.656
3.893LysSer: 3.893 ± 1.831
2.225LysThr: 2.225 ± 0.532
5.284LysVal: 5.284 ± 1.464
2.225LysTrp: 2.225 ± 0.731
1.39LysTyr: 1.39 ± 0.353
0.0LysXaa: 0.0 ± 0.0
Leu
5.84LeuAla: 5.84 ± 1.296
2.781LeuCys: 2.781 ± 0.754
7.23LeuAsp: 7.23 ± 0.91
5.284LeuGlu: 5.284 ± 1.205
3.893LeuPhe: 3.893 ± 1.472
7.23LeuGly: 7.23 ± 1.499
2.503LeuHis: 2.503 ± 0.751
5.562LeuIle: 5.562 ± 1.637
6.396LeuLys: 6.396 ± 2.084
7.23LeuLeu: 7.23 ± 1.023
5.284LeuMet: 5.284 ± 1.585
5.284LeuAsn: 5.284 ± 1.649
4.727LeuPro: 4.727 ± 2.476
2.225LeuGln: 2.225 ± 0.655
7.508LeuArg: 7.508 ± 1.868
10.845LeuSer: 10.845 ± 1.337
7.23LeuThr: 7.23 ± 1.813
3.615LeuVal: 3.615 ± 1.26
0.834LeuTrp: 0.834 ± 0.346
3.615LeuTyr: 3.615 ± 0.844
0.0LeuXaa: 0.0 ± 0.0
Met
1.947MetAla: 1.947 ± 1.059
0.278MetCys: 0.278 ± 0.153
1.947MetAsp: 1.947 ± 0.51
1.947MetGlu: 1.947 ± 0.735
1.39MetPhe: 1.39 ± 0.523
2.225MetGly: 2.225 ± 0.351
0.278MetHis: 0.278 ± 0.293
2.503MetIle: 2.503 ± 0.729
0.834MetLys: 0.834 ± 0.431
1.947MetLeu: 1.947 ± 0.689
0.834MetMet: 0.834 ± 0.459
0.278MetAsn: 0.278 ± 0.153
0.556MetPro: 0.556 ± 0.306
0.278MetGln: 0.278 ± 0.153
0.556MetArg: 0.556 ± 0.35
3.337MetSer: 3.337 ± 0.89
1.39MetThr: 1.39 ± 0.629
1.947MetVal: 1.947 ± 0.5
0.0MetTrp: 0.0 ± 0.0
0.556MetTyr: 0.556 ± 0.661
0.0MetXaa: 0.0 ± 0.0
Asn
2.503AsnAla: 2.503 ± 0.699
0.556AsnCys: 0.556 ± 0.306
0.556AsnAsp: 0.556 ± 0.306
2.503AsnGlu: 2.503 ± 0.697
1.112AsnPhe: 1.112 ± 0.612
2.781AsnGly: 2.781 ± 0.926
1.669AsnHis: 1.669 ± 0.56
2.781AsnIle: 2.781 ± 0.771
2.225AsnLys: 2.225 ± 0.95
4.449AsnLeu: 4.449 ± 1.29
1.39AsnMet: 1.39 ± 0.364
2.781AsnAsn: 2.781 ± 0.567
2.503AsnPro: 2.503 ± 0.902
1.947AsnGln: 1.947 ± 0.641
2.503AsnArg: 2.503 ± 1.012
3.615AsnSer: 3.615 ± 1.079
4.727AsnThr: 4.727 ± 0.836
1.669AsnVal: 1.669 ± 0.632
1.112AsnTrp: 1.112 ± 0.403
0.556AsnTyr: 0.556 ± 0.306
0.0AsnXaa: 0.0 ± 0.0
Pro
1.669ProAla: 1.669 ± 0.423
0.278ProCys: 0.278 ± 0.153
2.225ProAsp: 2.225 ± 0.619
4.449ProGlu: 4.449 ± 1.663
1.39ProPhe: 1.39 ± 0.884
1.669ProGly: 1.669 ± 0.33
1.947ProHis: 1.947 ± 0.5
2.781ProIle: 2.781 ± 0.644
4.449ProLys: 4.449 ± 1.873
4.449ProLeu: 4.449 ± 0.974
0.556ProMet: 0.556 ± 0.407
1.947ProAsn: 1.947 ± 0.447
3.615ProPro: 3.615 ± 1.461
1.112ProGln: 1.112 ± 0.811
1.669ProArg: 1.669 ± 1.469
6.396ProSer: 6.396 ± 1.521
3.059ProThr: 3.059 ± 0.744
3.337ProVal: 3.337 ± 1.302
0.556ProTrp: 0.556 ± 0.35
1.947ProTyr: 1.947 ± 0.5
0.0ProXaa: 0.0 ± 0.0
Gln
1.669GlnAla: 1.669 ± 0.33
0.834GlnCys: 0.834 ± 0.727
1.112GlnAsp: 1.112 ± 0.484
2.503GlnGlu: 2.503 ± 0.49
1.39GlnPhe: 1.39 ± 0.498
2.225GlnGly: 2.225 ± 0.974
1.112GlnHis: 1.112 ± 0.663
1.39GlnIle: 1.39 ± 1.011
2.225GlnLys: 2.225 ± 0.351
4.171GlnLeu: 4.171 ± 0.582
1.112GlnMet: 1.112 ± 0.701
1.112GlnAsn: 1.112 ± 0.403
1.112GlnPro: 1.112 ± 0.363
0.556GlnGln: 0.556 ± 1.057
1.669GlnArg: 1.669 ± 0.685
2.503GlnSer: 2.503 ± 0.774
1.39GlnThr: 1.39 ± 1.015
2.225GlnVal: 2.225 ± 0.351
0.0GlnTrp: 0.0 ± 0.0
1.39GlnTyr: 1.39 ± 1.215
0.0GlnXaa: 0.0 ± 0.0
Arg
4.727ArgAla: 4.727 ± 1.492
1.947ArgCys: 1.947 ± 1.177
3.615ArgAsp: 3.615 ± 1.324
2.503ArgGlu: 2.503 ± 0.67
2.225ArgPhe: 2.225 ± 0.628
1.669ArgGly: 1.669 ± 0.56
1.39ArgHis: 1.39 ± 0.508
3.059ArgIle: 3.059 ± 0.922
3.337ArgLys: 3.337 ± 1.835
6.118ArgLeu: 6.118 ± 1.658
1.112ArgMet: 1.112 ± 0.811
2.225ArgAsn: 2.225 ± 0.613
1.669ArgPro: 1.669 ± 0.705
2.781ArgGln: 2.781 ± 1.783
2.225ArgArg: 2.225 ± 0.793
4.449ArgSer: 4.449 ± 1.633
3.893ArgThr: 3.893 ± 1.453
3.615ArgVal: 3.615 ± 1.093
1.112ArgTrp: 1.112 ± 0.403
3.059ArgTyr: 3.059 ± 0.727
0.0ArgXaa: 0.0 ± 0.0
Ser
3.059SerAla: 3.059 ± 0.942
2.225SerCys: 2.225 ± 0.761
6.118SerAsp: 6.118 ± 1.594
4.727SerGlu: 4.727 ± 1.565
3.337SerPhe: 3.337 ± 0.963
3.893SerGly: 3.893 ± 1.831
3.059SerHis: 3.059 ± 1.256
3.893SerIle: 3.893 ± 0.665
3.893SerLys: 3.893 ± 1.203
8.343SerLeu: 8.343 ± 2.477
1.112SerMet: 1.112 ± 0.489
3.059SerAsn: 3.059 ± 1.916
3.337SerPro: 3.337 ± 0.941
2.781SerGln: 2.781 ± 0.755
5.284SerArg: 5.284 ± 1.274
5.284SerSer: 5.284 ± 0.725
5.284SerThr: 5.284 ± 0.562
3.893SerVal: 3.893 ± 1.293
2.225SerTrp: 2.225 ± 0.895
3.059SerTyr: 3.059 ± 0.59
0.0SerXaa: 0.0 ± 0.0
Thr
3.337ThrAla: 3.337 ± 0.915
0.834ThrCys: 0.834 ± 0.464
3.893ThrAsp: 3.893 ± 0.811
4.449ThrGlu: 4.449 ± 1.252
2.781ThrPhe: 2.781 ± 0.874
2.781ThrGly: 2.781 ± 0.705
1.39ThrHis: 1.39 ± 0.679
3.059ThrIle: 3.059 ± 0.616
1.947ThrLys: 1.947 ± 0.96
4.449ThrLeu: 4.449 ± 1.993
1.39ThrMet: 1.39 ± 0.38
2.781ThrAsn: 2.781 ± 0.265
2.225ThrPro: 2.225 ± 0.725
1.669ThrGln: 1.669 ± 0.691
2.503ThrArg: 2.503 ± 0.943
4.171ThrSer: 4.171 ± 0.883
2.225ThrThr: 2.225 ± 0.277
5.562ThrVal: 5.562 ± 1.583
2.225ThrTrp: 2.225 ± 0.471
2.503ThrTyr: 2.503 ± 0.784
0.0ThrXaa: 0.0 ± 0.0
Val
2.503ValAla: 2.503 ± 0.732
1.112ValCys: 1.112 ± 0.612
3.337ValAsp: 3.337 ± 1.052
3.059ValGlu: 3.059 ± 0.918
3.059ValPhe: 3.059 ± 0.81
4.727ValGly: 4.727 ± 1.145
2.225ValHis: 2.225 ± 0.798
4.171ValIle: 4.171 ± 1.21
5.84ValLys: 5.84 ± 1.511
6.118ValLeu: 6.118 ± 0.98
1.112ValMet: 1.112 ± 0.396
3.337ValAsn: 3.337 ± 0.979
1.669ValPro: 1.669 ± 0.423
3.059ValGln: 3.059 ± 0.547
2.503ValArg: 2.503 ± 0.642
3.615ValSer: 3.615 ± 0.713
3.615ValThr: 3.615 ± 0.992
3.893ValVal: 3.893 ± 1.581
1.112ValTrp: 1.112 ± 0.453
1.112ValTyr: 1.112 ± 0.381
0.0ValXaa: 0.0 ± 0.0
Trp
1.112TrpAla: 1.112 ± 0.612
0.0TrpCys: 0.0 ± 0.0
0.834TrpAsp: 0.834 ± 0.555
1.669TrpGlu: 1.669 ± 0.685
1.39TrpPhe: 1.39 ± 0.729
1.112TrpGly: 1.112 ± 0.612
0.278TrpHis: 0.278 ± 0.153
1.947TrpIle: 1.947 ± 0.344
1.947TrpLys: 1.947 ± 0.791
0.556TrpLeu: 0.556 ± 0.242
0.556TrpMet: 0.556 ± 0.407
1.947TrpAsn: 1.947 ± 0.735
1.112TrpPro: 1.112 ± 0.503
0.556TrpGln: 0.556 ± 0.407
0.278TrpArg: 0.278 ± 0.473
0.556TrpSer: 0.556 ± 0.306
0.556TrpThr: 0.556 ± 0.35
1.669TrpVal: 1.669 ± 0.861
0.278TrpTrp: 0.278 ± 0.153
0.556TrpTyr: 0.556 ± 0.242
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.503TyrAla: 2.503 ± 0.539
0.556TyrCys: 0.556 ± 0.613
0.556TyrAsp: 0.556 ± 0.242
1.112TyrGlu: 1.112 ± 0.735
1.669TyrPhe: 1.669 ± 0.507
2.225TyrGly: 2.225 ± 0.655
0.278TyrHis: 0.278 ± 0.153
1.39TyrIle: 1.39 ± 0.503
4.171TyrLys: 4.171 ± 0.152
5.006TyrLeu: 5.006 ± 1.187
0.278TyrMet: 0.278 ± 0.416
1.947TyrAsn: 1.947 ± 0.596
2.225TyrPro: 2.225 ± 0.62
0.834TyrGln: 0.834 ± 0.28
3.615TyrArg: 3.615 ± 0.713
2.781TyrSer: 2.781 ± 0.771
1.669TyrThr: 1.669 ± 0.839
2.781TyrVal: 2.781 ± 1.02
0.556TyrTrp: 0.556 ± 0.242
1.39TyrTyr: 1.39 ± 0.629
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3597 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski