Amino acid dipepetide frequency for Phascolarctobacterium succinatutens YIT 12067

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.822AlaAla: 11.822 ± 0.225
1.457AlaCys: 1.457 ± 0.046
5.761AlaAsp: 5.761 ± 0.107
6.87AlaGlu: 6.87 ± 0.132
3.508AlaPhe: 3.508 ± 0.084
7.523AlaGly: 7.523 ± 0.113
1.606AlaHis: 1.606 ± 0.048
5.622AlaIle: 5.622 ± 0.112
6.439AlaLys: 6.439 ± 0.115
9.155AlaLeu: 9.155 ± 0.135
2.999AlaMet: 2.999 ± 0.079
3.168AlaAsn: 3.168 ± 0.089
2.86AlaPro: 2.86 ± 0.079
3.578AlaGln: 3.578 ± 0.082
3.66AlaArg: 3.66 ± 0.09
4.096AlaSer: 4.096 ± 0.076
4.075AlaThr: 4.075 ± 0.087
7.977AlaVal: 7.977 ± 0.126
0.654AlaTrp: 0.654 ± 0.036
3.037AlaTyr: 3.037 ± 0.067
0.0AlaXaa: 0.0 ± 0.0
Cys
1.304CysAla: 1.304 ± 0.049
0.326CysCys: 0.326 ± 0.024
0.817CysAsp: 0.817 ± 0.037
0.874CysGlu: 0.874 ± 0.034
0.649CysPhe: 0.649 ± 0.032
1.66CysGly: 1.66 ± 0.058
0.309CysHis: 0.309 ± 0.02
0.952CysIle: 0.952 ± 0.04
0.766CysLys: 0.766 ± 0.037
1.375CysLeu: 1.375 ± 0.048
0.388CysMet: 0.388 ± 0.027
0.573CysAsn: 0.573 ± 0.032
0.684CysPro: 0.684 ± 0.036
0.334CysGln: 0.334 ± 0.023
0.778CysArg: 0.778 ± 0.037
0.965CysSer: 0.965 ± 0.037
0.684CysThr: 0.684 ± 0.03
1.001CysVal: 1.001 ± 0.046
0.132CysTrp: 0.132 ± 0.014
0.489CysTyr: 0.489 ± 0.026
0.0CysXaa: 0.0 ± 0.0
Asp
4.799AspAla: 4.799 ± 0.095
0.764AspCys: 0.764 ± 0.036
2.771AspAsp: 2.771 ± 0.08
3.97AspGlu: 3.97 ± 0.098
2.541AspPhe: 2.541 ± 0.063
3.902AspGly: 3.902 ± 0.085
0.726AspHis: 0.726 ± 0.037
4.272AspIle: 4.272 ± 0.086
4.284AspLys: 4.284 ± 0.083
4.32AspLeu: 4.32 ± 0.081
1.729AspMet: 1.729 ± 0.058
2.343AspAsn: 2.343 ± 0.068
1.533AspPro: 1.533 ± 0.052
0.88AspGln: 0.88 ± 0.035
2.012AspArg: 2.012 ± 0.052
2.577AspSer: 2.577 ± 0.065
2.485AspThr: 2.485 ± 0.058
4.072AspVal: 4.072 ± 0.087
0.548AspTrp: 0.548 ± 0.028
2.243AspTyr: 2.243 ± 0.061
0.0AspXaa: 0.0 ± 0.0
Glu
6.757GluAla: 6.757 ± 0.116
0.665GluCys: 0.665 ± 0.031
3.176GluAsp: 3.176 ± 0.076
5.016GluGlu: 5.016 ± 0.109
2.216GluPhe: 2.216 ± 0.059
4.156GluGly: 4.156 ± 0.078
1.566GluHis: 1.566 ± 0.051
4.368GluIle: 4.368 ± 0.1
4.957GluLys: 4.957 ± 0.111
7.166GluLeu: 7.166 ± 0.118
2.131GluMet: 2.131 ± 0.049
2.988GluAsn: 2.988 ± 0.076
1.926GluPro: 1.926 ± 0.056
3.16GluGln: 3.16 ± 0.082
3.707GluArg: 3.707 ± 0.093
2.456GluSer: 2.456 ± 0.068
2.666GluThr: 2.666 ± 0.075
4.311GluVal: 4.311 ± 0.09
0.489GluTrp: 0.489 ± 0.029
2.4GluTyr: 2.4 ± 0.069
0.0GluXaa: 0.0 ± 0.0
Phe
3.935PheAla: 3.935 ± 0.089
0.72PheCys: 0.72 ± 0.036
2.353PheAsp: 2.353 ± 0.066
2.065PheGlu: 2.065 ± 0.064
1.891PhePhe: 1.891 ± 0.073
3.19PheGly: 3.19 ± 0.086
0.673PheHis: 0.673 ± 0.033
2.728PheIle: 2.728 ± 0.074
2.119PheLys: 2.119 ± 0.057
3.679PheLeu: 3.679 ± 0.1
1.24PheMet: 1.24 ± 0.051
1.667PheAsn: 1.667 ± 0.049
1.331PhePro: 1.331 ± 0.043
0.887PheGln: 0.887 ± 0.038
1.452PheArg: 1.452 ± 0.052
2.486PheSer: 2.486 ± 0.065
2.265PheThr: 2.265 ± 0.051
2.822PheVal: 2.822 ± 0.07
0.408PheTrp: 0.408 ± 0.03
1.45PheTyr: 1.45 ± 0.052
0.0PheXaa: 0.0 ± 0.0
Gly
6.456GlyAla: 6.456 ± 0.134
1.421GlyCys: 1.421 ± 0.052
3.505GlyAsp: 3.505 ± 0.069
4.344GlyGlu: 4.344 ± 0.086
3.074GlyPhe: 3.074 ± 0.076
5.662GlyGly: 5.662 ± 0.11
1.417GlyHis: 1.417 ± 0.053
5.407GlyIle: 5.407 ± 0.093
5.487GlyLys: 5.487 ± 0.094
6.619GlyLeu: 6.619 ± 0.115
2.485GlyMet: 2.485 ± 0.074
2.733GlyAsn: 2.733 ± 0.074
1.565GlyPro: 1.565 ± 0.059
2.111GlyGln: 2.111 ± 0.057
3.599GlyArg: 3.599 ± 0.074
4.379GlySer: 4.379 ± 0.087
4.015GlyThr: 4.015 ± 0.075
5.692GlyVal: 5.692 ± 0.112
0.745GlyTrp: 0.745 ± 0.035
2.943GlyTyr: 2.943 ± 0.06
0.0GlyXaa: 0.0 ± 0.0
His
1.441HisAla: 1.441 ± 0.044
0.358HisCys: 0.358 ± 0.023
1.03HisAsp: 1.03 ± 0.036
1.152HisGlu: 1.152 ± 0.04
0.79HisPhe: 0.79 ± 0.033
1.468HisGly: 1.468 ± 0.049
0.4HisHis: 0.4 ± 0.026
1.382HisIle: 1.382 ± 0.05
1.127HisLys: 1.127 ± 0.04
1.716HisLeu: 1.716 ± 0.058
0.519HisMet: 0.519 ± 0.032
0.882HisAsn: 0.882 ± 0.036
0.955HisPro: 0.955 ± 0.038
0.571HisGln: 0.571 ± 0.031
0.869HisArg: 0.869 ± 0.045
0.96HisSer: 0.96 ± 0.046
0.987HisThr: 0.987 ± 0.043
1.297HisVal: 1.297 ± 0.048
0.196HisTrp: 0.196 ± 0.018
0.796HisTyr: 0.796 ± 0.035
0.0HisXaa: 0.0 ± 0.0
Ile
6.391IleAla: 6.391 ± 0.103
1.235IleCys: 1.235 ± 0.047
3.674IleAsp: 3.674 ± 0.08
3.824IleGlu: 3.824 ± 0.077
2.577IlePhe: 2.577 ± 0.073
4.908IleGly: 4.908 ± 0.096
1.119IleHis: 1.119 ± 0.044
4.904IleIle: 4.904 ± 0.115
4.01IleLys: 4.01 ± 0.08
5.641IleLeu: 5.641 ± 0.107
2.044IleMet: 2.044 ± 0.066
2.921IleAsn: 2.921 ± 0.07
2.711IlePro: 2.711 ± 0.073
1.536IleGln: 1.536 ± 0.052
2.703IleArg: 2.703 ± 0.066
3.889IleSer: 3.889 ± 0.084
3.82IleThr: 3.82 ± 0.083
4.957IleVal: 4.957 ± 0.11
0.565IleTrp: 0.565 ± 0.034
2.235IleTyr: 2.235 ± 0.063
0.0IleXaa: 0.0 ± 0.0
Lys
6.012LysAla: 6.012 ± 0.117
0.688LysCys: 0.688 ± 0.033
3.435LysAsp: 3.435 ± 0.091
4.976LysGlu: 4.976 ± 0.105
2.028LysPhe: 2.028 ± 0.059
4.013LysGly: 4.013 ± 0.086
1.205LysHis: 1.205 ± 0.043
4.497LysIle: 4.497 ± 0.102
4.884LysLys: 4.884 ± 0.107
6.596LysLeu: 6.596 ± 0.106
2.458LysMet: 2.458 ± 0.06
3.179LysAsn: 3.179 ± 0.08
2.273LysPro: 2.273 ± 0.069
2.784LysGln: 2.784 ± 0.064
2.926LysArg: 2.926 ± 0.077
2.797LysSer: 2.797 ± 0.059
3.209LysThr: 3.209 ± 0.074
4.524LysVal: 4.524 ± 0.095
0.505LysTrp: 0.505 ± 0.03
2.404LysTyr: 2.404 ± 0.064
0.0LysXaa: 0.0 ± 0.0
Leu
10.229LeuAla: 10.229 ± 0.146
1.487LeuCys: 1.487 ± 0.052
5.041LeuAsp: 5.041 ± 0.091
6.122LeuGlu: 6.122 ± 0.112
3.489LeuPhe: 3.489 ± 0.094
6.795LeuGly: 6.795 ± 0.113
2.039LeuHis: 2.039 ± 0.066
5.121LeuIle: 5.121 ± 0.097
5.525LeuLys: 5.525 ± 0.101
11.085LeuLeu: 11.085 ± 0.217
2.806LeuMet: 2.806 ± 0.069
3.574LeuAsn: 3.574 ± 0.081
4.75LeuPro: 4.75 ± 0.094
4.627LeuGln: 4.627 ± 0.106
4.971LeuArg: 4.971 ± 0.1
5.438LeuSer: 5.438 ± 0.104
5.212LeuThr: 5.212 ± 0.094
6.447LeuVal: 6.447 ± 0.116
0.772LeuTrp: 0.772 ± 0.035
2.953LeuTyr: 2.953 ± 0.073
0.0LeuXaa: 0.0 ± 0.0
Met
3.012MetAla: 3.012 ± 0.069
0.353MetCys: 0.353 ± 0.025
1.597MetAsp: 1.597 ± 0.048
2.017MetGlu: 2.017 ± 0.061
1.062MetPhe: 1.062 ± 0.042
2.189MetGly: 2.189 ± 0.066
0.632MetHis: 0.632 ± 0.029
1.643MetIle: 1.643 ± 0.053
1.948MetLys: 1.948 ± 0.055
3.636MetLeu: 3.636 ± 0.082
0.947MetMet: 0.947 ± 0.039
1.23MetAsn: 1.23 ± 0.047
1.262MetPro: 1.262 ± 0.045
1.511MetGln: 1.511 ± 0.051
1.593MetArg: 1.593 ± 0.05
1.741MetSer: 1.741 ± 0.056
1.705MetThr: 1.705 ± 0.05
1.972MetVal: 1.972 ± 0.06
0.17MetTrp: 0.17 ± 0.016
0.907MetTyr: 0.907 ± 0.038
0.0MetXaa: 0.0 ± 0.0
Asn
3.344AsnAla: 3.344 ± 0.081
0.57AsnCys: 0.57 ± 0.034
1.98AsnAsp: 1.98 ± 0.056
2.318AsnGlu: 2.318 ± 0.066
1.605AsnPhe: 1.605 ± 0.046
3.093AsnGly: 3.093 ± 0.07
0.729AsnHis: 0.729 ± 0.027
3.332AsnIle: 3.332 ± 0.068
2.84AsnLys: 2.84 ± 0.079
3.656AsnLeu: 3.656 ± 0.075
1.324AsnMet: 1.324 ± 0.047
1.77AsnAsn: 1.77 ± 0.067
2.081AsnPro: 2.081 ± 0.07
0.963AsnGln: 0.963 ± 0.04
1.563AsnArg: 1.563 ± 0.054
2.057AsnSer: 2.057 ± 0.071
2.074AsnThr: 2.074 ± 0.058
3.052AsnVal: 3.052 ± 0.07
0.39AsnTrp: 0.39 ± 0.028
1.667AsnTyr: 1.667 ± 0.058
0.0AsnXaa: 0.0 ± 0.0
Pro
3.477ProAla: 3.477 ± 0.077
0.533ProCys: 0.533 ± 0.033
2.2ProAsp: 2.2 ± 0.053
3.421ProGlu: 3.421 ± 0.088
1.511ProPhe: 1.511 ± 0.045
2.639ProGly: 2.639 ± 0.066
0.716ProHis: 0.716 ± 0.033
1.987ProIle: 1.987 ± 0.067
2.187ProLys: 2.187 ± 0.059
3.484ProLeu: 3.484 ± 0.087
0.969ProMet: 0.969 ± 0.035
1.267ProAsn: 1.267 ± 0.047
1.076ProPro: 1.076 ± 0.045
1.64ProGln: 1.64 ± 0.055
1.245ProArg: 1.245 ± 0.04
1.59ProSer: 1.59 ± 0.045
1.698ProThr: 1.698 ± 0.054
3.289ProVal: 3.289 ± 0.081
0.352ProTrp: 0.352 ± 0.026
1.367ProTyr: 1.367 ± 0.047
0.0ProXaa: 0.0 ± 0.0
Gln
3.537GlnAla: 3.537 ± 0.09
0.388GlnCys: 0.388 ± 0.026
1.554GlnAsp: 1.554 ± 0.053
2.762GlnGlu: 2.762 ± 0.078
1.073GlnPhe: 1.073 ± 0.043
2.283GlnGly: 2.283 ± 0.071
0.767GlnHis: 0.767 ± 0.036
2.168GlnIle: 2.168 ± 0.064
2.498GlnLys: 2.498 ± 0.068
3.852GlnLeu: 3.852 ± 0.095
1.109GlnMet: 1.109 ± 0.041
1.39GlnAsn: 1.39 ± 0.052
1.32GlnPro: 1.32 ± 0.048
2.181GlnGln: 2.181 ± 0.09
1.928GlnArg: 1.928 ± 0.06
1.716GlnSer: 1.716 ± 0.054
1.589GlnThr: 1.589 ± 0.049
2.233GlnVal: 2.233 ± 0.059
0.31GlnTrp: 0.31 ± 0.024
1.145GlnTyr: 1.145 ± 0.048
0.0GlnXaa: 0.0 ± 0.0
Arg
3.338ArgAla: 3.338 ± 0.077
0.753ArgCys: 0.753 ± 0.039
2.123ArgAsp: 2.123 ± 0.063
3.243ArgGlu: 3.243 ± 0.08
2.025ArgPhe: 2.025 ± 0.056
2.843ArgGly: 2.843 ± 0.073
0.893ArgHis: 0.893 ± 0.037
3.15ArgIle: 3.15 ± 0.061
3.023ArgLys: 3.023 ± 0.062
4.75ArgLeu: 4.75 ± 0.093
1.453ArgMet: 1.453 ± 0.047
1.964ArgAsn: 1.964 ± 0.057
1.627ArgPro: 1.627 ± 0.056
1.939ArgGln: 1.939 ± 0.067
2.498ArgArg: 2.498 ± 0.071
2.375ArgSer: 2.375 ± 0.063
2.235ArgThr: 2.235 ± 0.06
2.959ArgVal: 2.959 ± 0.069
0.412ArgTrp: 0.412 ± 0.027
1.73ArgTyr: 1.73 ± 0.053
0.0ArgXaa: 0.0 ± 0.0
Ser
4.377SerAla: 4.377 ± 0.075
0.823SerCys: 0.823 ± 0.037
2.544SerAsp: 2.544 ± 0.062
3.11SerGlu: 3.11 ± 0.071
2.49SerPhe: 2.49 ± 0.065
4.503SerGly: 4.503 ± 0.078
0.909SerHis: 0.909 ± 0.042
3.227SerIle: 3.227 ± 0.078
3.306SerLys: 3.306 ± 0.067
5.167SerLeu: 5.167 ± 0.094
1.691SerMet: 1.691 ± 0.052
1.99SerAsn: 1.99 ± 0.061
1.605SerPro: 1.605 ± 0.05
1.426SerGln: 1.426 ± 0.048
2.335SerArg: 2.335 ± 0.066
2.918SerSer: 2.918 ± 0.069
2.475SerThr: 2.475 ± 0.068
4.011SerVal: 4.011 ± 0.076
0.521SerTrp: 0.521 ± 0.031
1.967SerTyr: 1.967 ± 0.054
0.0SerXaa: 0.0 ± 0.0
Thr
5.226ThrAla: 5.226 ± 0.097
0.608ThrCys: 0.608 ± 0.031
2.77ThrAsp: 2.77 ± 0.07
2.972ThrGlu: 2.972 ± 0.074
1.928ThrPhe: 1.928 ± 0.058
4.401ThrGly: 4.401 ± 0.083
0.965ThrHis: 0.965 ± 0.036
3.313ThrIle: 3.313 ± 0.068
2.868ThrLys: 2.868 ± 0.069
4.693ThrLeu: 4.693 ± 0.09
1.433ThrMet: 1.433 ± 0.046
1.853ThrAsn: 1.853 ± 0.054
2.356ThrPro: 2.356 ± 0.059
1.528ThrGln: 1.528 ± 0.05
1.875ThrArg: 1.875 ± 0.049
2.548ThrSer: 2.548 ± 0.057
2.698ThrThr: 2.698 ± 0.075
4.236ThrVal: 4.236 ± 0.089
0.428ThrTrp: 0.428 ± 0.029
1.651ThrTyr: 1.651 ± 0.053
0.0ThrXaa: 0.0 ± 0.0
Val
6.733ValAla: 6.733 ± 0.131
1.202ValCys: 1.202 ± 0.046
3.922ValAsp: 3.922 ± 0.081
4.602ValGlu: 4.602 ± 0.098
2.896ValPhe: 2.896 ± 0.067
5.11ValGly: 5.11 ± 0.11
1.256ValHis: 1.256 ± 0.045
4.978ValIle: 4.978 ± 0.106
4.5ValLys: 4.5 ± 0.091
7.362ValLeu: 7.362 ± 0.13
2.106ValMet: 2.106 ± 0.05
2.889ValAsn: 2.889 ± 0.079
3.087ValPro: 3.087 ± 0.074
2.442ValGln: 2.442 ± 0.063
3.524ValArg: 3.524 ± 0.076
3.945ValSer: 3.945 ± 0.078
4.137ValThr: 4.137 ± 0.092
5.579ValVal: 5.579 ± 0.1
0.559ValTrp: 0.559 ± 0.029
2.405ValTyr: 2.405 ± 0.058
0.0ValXaa: 0.0 ± 0.0
Trp
0.589TrpAla: 0.589 ± 0.029
0.121TrpCys: 0.121 ± 0.014
0.431TrpAsp: 0.431 ± 0.027
0.581TrpGlu: 0.581 ± 0.028
0.396TrpPhe: 0.396 ± 0.026
0.606TrpGly: 0.606 ± 0.028
0.223TrpHis: 0.223 ± 0.02
0.409TrpIle: 0.409 ± 0.025
0.444TrpLys: 0.444 ± 0.026
1.086TrpLeu: 1.086 ± 0.049
0.253TrpMet: 0.253 ± 0.019
0.352TrpAsn: 0.352 ± 0.026
0.314TrpPro: 0.314 ± 0.023
0.606TrpGln: 0.606 ± 0.029
0.435TrpArg: 0.435 ± 0.025
0.474TrpSer: 0.474 ± 0.027
0.385TrpThr: 0.385 ± 0.027
0.492TrpVal: 0.492 ± 0.027
0.116TrpTrp: 0.116 ± 0.013
0.323TrpTyr: 0.323 ± 0.026
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.087TyrAla: 3.087 ± 0.074
0.589TyrCys: 0.589 ± 0.033
2.087TyrAsp: 2.087 ± 0.062
2.041TyrGlu: 2.041 ± 0.058
1.613TyrPhe: 1.613 ± 0.056
2.716TyrGly: 2.716 ± 0.07
0.745TyrHis: 0.745 ± 0.031
2.206TyrIle: 2.206 ± 0.062
2.181TyrLys: 2.181 ± 0.059
3.445TyrLeu: 3.445 ± 0.082
1.041TyrMet: 1.041 ± 0.038
1.675TyrAsn: 1.675 ± 0.057
1.334TyrPro: 1.334 ± 0.047
1.097TyrGln: 1.097 ± 0.046
1.66TyrArg: 1.66 ± 0.055
1.988TyrSer: 1.988 ± 0.062
1.934TyrThr: 1.934 ± 0.061
2.31TyrVal: 2.31 ± 0.065
0.366TyrTrp: 0.366 ± 0.026
1.523TyrTyr: 1.523 ± 0.047
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2148 proteins (628214 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski