Amino acid dipepetide frequency for Cherry rasp leaf virus (isolate Potato/United States) (CRLV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.479AlaAla: 7.479 ± 0.707
2.493AlaCys: 2.493 ± 0.837
2.805AlaAsp: 2.805 ± 1.618
5.921AlaGlu: 5.921 ± 1.996
2.181AlaPhe: 2.181 ± 0.056
3.116AlaGly: 3.116 ± 0.595
1.558AlaHis: 1.558 ± 0.298
5.298AlaIle: 5.298 ± 0.651
6.232AlaLys: 6.232 ± 1.792
11.218AlaLeu: 11.218 ± 0.142
3.739AlaMet: 3.739 ± 0.248
3.116AlaAsn: 3.116 ± 0.006
4.674AlaPro: 4.674 ± 1.494
2.493AlaGln: 2.493 ± 0.236
3.739AlaArg: 3.739 ± 0.849
6.544AlaSer: 6.544 ± 0.769
2.493AlaThr: 2.493 ± 0.236
3.116AlaVal: 3.116 ± 1.209
0.935AlaTrp: 0.935 ± 0.539
2.493AlaTyr: 2.493 ± 0.236
0.0AlaXaa: 0.0 ± 0.0
Cys
1.246CysAla: 1.246 ± 0.719
0.0CysCys: 0.0 ± 0.0
0.623CysAsp: 0.623 ± 0.242
1.246CysGlu: 1.246 ± 0.719
2.493CysPhe: 2.493 ± 1.439
2.181CysGly: 2.181 ± 1.748
0.0CysHis: 0.0 ± 0.0
1.87CysIle: 1.87 ± 0.478
1.246CysLys: 1.246 ± 0.118
2.181CysLeu: 2.181 ± 0.657
0.312CysMet: 0.312 ± 0.18
1.246CysAsn: 1.246 ± 0.118
0.623CysPro: 0.623 ± 0.36
0.312CysGln: 0.312 ± 0.18
0.312CysArg: 0.312 ± 0.18
2.493CysSer: 2.493 ± 0.837
1.87CysThr: 1.87 ± 0.124
1.246CysVal: 1.246 ± 0.484
0.0CysTrp: 0.0 ± 0.0
1.246CysTyr: 1.246 ± 0.118
0.0CysXaa: 0.0 ± 0.0
Asp
4.051AspAla: 4.051 ± 1.135
0.312AspCys: 0.312 ± 0.18
2.805AspAsp: 2.805 ± 0.787
2.493AspGlu: 2.493 ± 0.837
4.986AspPhe: 4.986 ± 0.472
2.493AspGly: 2.493 ± 0.837
0.623AspHis: 0.623 ± 0.242
0.623AspIle: 0.623 ± 0.242
2.181AspLys: 2.181 ± 0.657
6.544AspLeu: 6.544 ± 1.035
0.623AspMet: 0.623 ± 0.242
0.623AspAsn: 0.623 ± 0.36
1.87AspPro: 1.87 ± 1.327
1.87AspGln: 1.87 ± 0.725
2.493AspArg: 2.493 ± 0.236
4.051AspSer: 4.051 ± 0.533
2.805AspThr: 2.805 ± 0.787
4.051AspVal: 4.051 ± 0.068
0.935AspTrp: 0.935 ± 0.062
2.181AspTyr: 2.181 ± 0.657
0.0AspXaa: 0.0 ± 0.0
Glu
4.674GluAla: 4.674 ± 0.893
0.935GluCys: 0.935 ± 0.539
2.805GluAsp: 2.805 ± 0.186
3.739GluGlu: 3.739 ± 0.248
3.116GluPhe: 3.116 ± 0.006
4.363GluGly: 4.363 ± 0.112
1.558GluHis: 1.558 ± 0.899
2.181GluIle: 2.181 ± 0.657
4.051GluLys: 4.051 ± 0.068
3.116GluLeu: 3.116 ± 1.209
1.246GluMet: 1.246 ± 0.719
3.116GluAsn: 3.116 ± 0.006
3.116GluPro: 3.116 ± 1.197
2.805GluGln: 2.805 ± 0.416
3.739GluArg: 3.739 ± 0.849
3.116GluSer: 3.116 ± 1.81
3.739GluThr: 3.739 ± 0.248
3.739GluVal: 3.739 ± 0.354
0.312GluTrp: 0.312 ± 0.18
1.246GluTyr: 1.246 ± 0.118
0.0GluXaa: 0.0 ± 0.0
Phe
2.181PheAla: 2.181 ± 0.056
1.558PheCys: 1.558 ± 0.899
3.116PheAsp: 3.116 ± 0.607
3.428PheGlu: 3.428 ± 1.377
2.181PhePhe: 2.181 ± 1.259
4.051PheGly: 4.051 ± 1.271
1.558PheHis: 1.558 ± 0.905
0.623PheIle: 0.623 ± 0.36
1.87PheLys: 1.87 ± 0.478
8.102PheLeu: 8.102 ± 4.675
0.0PheMet: 0.0 ± 0.0
3.739PheAsn: 3.739 ± 0.248
3.428PhePro: 3.428 ± 1.029
1.558PheGln: 1.558 ± 0.304
0.935PheArg: 0.935 ± 0.663
8.725PheSer: 8.725 ± 4.587
2.805PheThr: 2.805 ± 0.186
4.363PheVal: 4.363 ± 0.112
0.623PheTrp: 0.623 ± 0.36
2.181PheTyr: 2.181 ± 0.056
0.0PheXaa: 0.0 ± 0.0
Gly
4.363GlyAla: 4.363 ± 0.49
0.623GlyCys: 0.623 ± 0.242
3.428GlyAsp: 3.428 ± 0.428
3.116GlyGlu: 3.116 ± 1.197
3.739GlyPhe: 3.739 ± 0.849
3.116GlyGly: 3.116 ± 1.209
1.558GlyHis: 1.558 ± 0.304
4.363GlyIle: 4.363 ± 0.713
1.246GlyLys: 1.246 ± 0.118
4.363GlyLeu: 4.363 ± 1.315
1.246GlyMet: 1.246 ± 0.118
1.246GlyAsn: 1.246 ± 0.118
3.739GlyPro: 3.739 ± 0.248
2.493GlyGln: 2.493 ± 1.568
3.428GlyArg: 3.428 ± 2.232
4.051GlySer: 4.051 ± 1.271
4.051GlyThr: 4.051 ± 1.271
4.051GlyVal: 4.051 ± 0.533
0.312GlyTrp: 0.312 ± 0.18
2.493GlyTyr: 2.493 ± 0.236
0.0GlyXaa: 0.0 ± 0.0
His
0.935HisAla: 0.935 ± 0.062
0.623HisCys: 0.623 ± 0.242
0.935HisAsp: 0.935 ± 0.062
0.623HisGlu: 0.623 ± 0.36
1.558HisPhe: 1.558 ± 0.304
1.558HisGly: 1.558 ± 0.304
0.0HisHis: 0.0 ± 0.0
1.246HisIle: 1.246 ± 0.118
1.246HisLys: 1.246 ± 0.118
1.87HisLeu: 1.87 ± 0.725
1.246HisMet: 1.246 ± 0.118
1.246HisAsn: 1.246 ± 0.484
0.935HisPro: 0.935 ± 0.062
1.558HisGln: 1.558 ± 0.304
0.623HisArg: 0.623 ± 0.36
1.87HisSer: 1.87 ± 0.478
0.0HisThr: 0.0 ± 0.0
2.181HisVal: 2.181 ± 0.545
0.623HisTrp: 0.623 ± 0.36
0.623HisTyr: 0.623 ± 0.242
0.0HisXaa: 0.0 ± 0.0
Ile
3.739IleAla: 3.739 ± 1.556
1.558IleCys: 1.558 ± 0.304
1.87IleAsp: 1.87 ± 0.124
1.246IleGlu: 1.246 ± 0.118
4.674IlePhe: 4.674 ± 0.893
2.181IleGly: 2.181 ± 0.657
0.623IleHis: 0.623 ± 0.242
2.181IleIle: 2.181 ± 0.056
2.181IleLys: 2.181 ± 0.056
4.674IleLeu: 4.674 ± 1.494
0.623IleMet: 0.623 ± 0.242
1.87IleAsn: 1.87 ± 0.725
2.805IlePro: 2.805 ± 0.416
1.558IleGln: 1.558 ± 0.298
1.246IleArg: 1.246 ± 0.118
5.298IleSer: 5.298 ± 0.05
3.116IleThr: 3.116 ± 0.006
4.051IleVal: 4.051 ± 0.533
0.0IleTrp: 0.0 ± 0.0
0.935IleTyr: 0.935 ± 0.539
0.0IleXaa: 0.0 ± 0.0
Lys
6.544LysAla: 6.544 ± 1.371
0.312LysCys: 0.312 ± 0.18
3.428LysAsp: 3.428 ± 1.377
4.051LysGlu: 4.051 ± 2.473
1.87LysPhe: 1.87 ± 1.079
3.116LysGly: 3.116 ± 0.006
2.181LysHis: 2.181 ± 0.056
2.493LysIle: 2.493 ± 0.236
2.181LysLys: 2.181 ± 0.657
4.363LysLeu: 4.363 ± 0.112
0.935LysMet: 0.935 ± 0.635
2.805LysAsn: 2.805 ± 1.017
1.87LysPro: 1.87 ± 0.478
1.246LysGln: 1.246 ± 0.118
3.428LysArg: 3.428 ± 0.775
3.116LysSer: 3.116 ± 0.006
2.181LysThr: 2.181 ± 0.056
3.116LysVal: 3.116 ± 1.197
0.935LysTrp: 0.935 ± 0.539
2.805LysTyr: 2.805 ± 0.186
0.0LysXaa: 0.0 ± 0.0
Leu
10.595LeuAla: 10.595 ± 0.502
4.363LeuCys: 4.363 ± 1.315
5.609LeuAsp: 5.609 ± 1.433
5.298LeuGlu: 5.298 ± 1.854
5.609LeuPhe: 5.609 ± 0.23
5.609LeuGly: 5.609 ± 0.372
2.805LeuHis: 2.805 ± 0.787
6.232LeuIle: 6.232 ± 0.589
5.921LeuLys: 5.921 ± 0.41
8.102LeuLeu: 8.102 ± 1.339
1.87LeuMet: 1.87 ± 0.124
6.232LeuAsn: 6.232 ± 0.613
6.856LeuPro: 6.856 ± 0.348
1.246LeuGln: 1.246 ± 0.118
4.363LeuArg: 4.363 ± 0.49
6.544LeuSer: 6.544 ± 0.168
5.298LeuThr: 5.298 ± 0.551
7.791LeuVal: 7.791 ± 0.887
1.246LeuTrp: 1.246 ± 0.118
3.116LeuTyr: 3.116 ± 0.607
0.0LeuXaa: 0.0 ± 0.0
Met
3.116MetAla: 3.116 ± 0.595
0.312MetCys: 0.312 ± 0.422
1.246MetAsp: 1.246 ± 0.118
1.246MetGlu: 1.246 ± 0.484
0.623MetPhe: 0.623 ± 0.242
0.935MetGly: 0.935 ± 0.062
0.312MetHis: 0.312 ± 0.18
0.623MetIle: 0.623 ± 0.242
1.558MetLys: 1.558 ± 0.298
1.87MetLeu: 1.87 ± 0.478
0.312MetMet: 0.312 ± 0.18
0.0MetAsn: 0.0 ± 0.0
2.493MetPro: 2.493 ± 0.967
1.87MetGln: 1.87 ± 1.079
1.558MetArg: 1.558 ± 0.905
0.935MetSer: 0.935 ± 0.062
0.312MetThr: 0.312 ± 0.18
0.935MetVal: 0.935 ± 0.539
0.312MetTrp: 0.312 ± 0.422
0.312MetTyr: 0.312 ± 0.18
0.0MetXaa: 0.0 ± 0.0
Asn
1.87AsnAla: 1.87 ± 0.725
0.935AsnCys: 0.935 ± 0.539
2.181AsnAsp: 2.181 ± 0.657
4.051AsnGlu: 4.051 ± 1.271
4.051AsnPhe: 4.051 ± 0.669
3.116AsnGly: 3.116 ± 0.595
0.935AsnHis: 0.935 ± 0.539
2.493AsnIle: 2.493 ± 0.366
3.116AsnLys: 3.116 ± 1.209
5.921AsnLeu: 5.921 ± 1.996
1.87AsnMet: 1.87 ± 0.124
1.558AsnAsn: 1.558 ± 0.304
1.87AsnPro: 1.87 ± 0.124
0.623AsnGln: 0.623 ± 0.36
2.181AsnArg: 2.181 ± 0.056
3.739AsnSer: 3.739 ± 0.248
1.246AsnThr: 1.246 ± 0.484
2.805AsnVal: 2.805 ± 0.787
0.623AsnTrp: 0.623 ± 0.242
1.246AsnTyr: 1.246 ± 0.719
0.0AsnXaa: 0.0 ± 0.0
Pro
3.116ProAla: 3.116 ± 1.197
1.246ProCys: 1.246 ± 0.719
3.116ProAsp: 3.116 ± 1.81
4.051ProGlu: 4.051 ± 0.533
4.363ProPhe: 4.363 ± 0.713
1.87ProGly: 1.87 ± 0.124
1.246ProHis: 1.246 ± 0.484
1.246ProIle: 1.246 ± 0.484
3.116ProLys: 3.116 ± 1.197
6.232ProLeu: 6.232 ± 0.012
0.0ProMet: 0.0 ± 0.0
1.87ProAsn: 1.87 ± 1.327
3.428ProPro: 3.428 ± 0.775
0.935ProGln: 0.935 ± 0.062
3.739ProArg: 3.739 ± 0.248
4.674ProSer: 4.674 ± 0.31
3.428ProThr: 3.428 ± 0.174
4.051ProVal: 4.051 ± 0.533
0.0ProTrp: 0.0 ± 0.0
1.558ProTyr: 1.558 ± 0.304
0.0ProXaa: 0.0 ± 0.0
Gln
2.493GlnAla: 2.493 ± 0.366
0.935GlnCys: 0.935 ± 0.663
1.246GlnAsp: 1.246 ± 0.118
1.558GlnGlu: 1.558 ± 0.298
0.623GlnPhe: 0.623 ± 0.242
2.493GlnGly: 2.493 ± 0.366
0.935GlnHis: 0.935 ± 0.062
0.623GlnIle: 0.623 ± 0.36
1.558GlnLys: 1.558 ± 0.899
4.051GlnLeu: 4.051 ± 0.669
0.935GlnMet: 0.935 ± 0.062
1.246GlnAsn: 1.246 ± 1.085
0.312GlnPro: 0.312 ± 0.18
1.246GlnGln: 1.246 ± 0.719
1.87GlnArg: 1.87 ± 0.478
1.246GlnSer: 1.246 ± 0.484
2.493GlnThr: 2.493 ± 0.837
4.363GlnVal: 4.363 ± 0.112
0.0GlnTrp: 0.0 ± 0.0
0.312GlnTyr: 0.312 ± 0.18
0.0GlnXaa: 0.0 ± 0.0
Arg
4.051ArgAla: 4.051 ± 0.669
2.181ArgCys: 2.181 ± 0.545
2.181ArgAsp: 2.181 ± 0.056
1.87ArgGlu: 1.87 ± 1.079
2.805ArgPhe: 2.805 ± 0.787
2.493ArgGly: 2.493 ± 0.366
0.623ArgHis: 0.623 ± 0.242
3.428ArgIle: 3.428 ± 0.775
1.87ArgLys: 1.87 ± 0.478
3.739ArgLeu: 3.739 ± 0.354
0.0ArgMet: 0.0 ± 0.0
4.051ArgAsn: 4.051 ± 0.669
1.558ArgPro: 1.558 ± 0.905
2.493ArgGln: 2.493 ± 0.236
3.116ArgArg: 3.116 ± 1.197
5.609ArgSer: 5.609 ± 0.372
1.87ArgThr: 1.87 ± 0.725
3.739ArgVal: 3.739 ± 2.052
0.0ArgTrp: 0.0 ± 0.0
1.558ArgTyr: 1.558 ± 0.304
0.0ArgXaa: 0.0 ± 0.0
Ser
5.298SerAla: 5.298 ± 2.957
1.558SerCys: 1.558 ± 0.304
3.739SerAsp: 3.739 ± 0.354
3.739SerGlu: 3.739 ± 0.354
6.232SerPhe: 6.232 ± 1.816
5.921SerGly: 5.921 ± 2.597
1.558SerHis: 1.558 ± 0.304
3.739SerIle: 3.739 ± 0.354
5.298SerLys: 5.298 ± 0.05
10.907SerLeu: 10.907 ± 0.28
0.623SerMet: 0.623 ± 0.242
3.428SerAsn: 3.428 ± 0.174
4.674SerPro: 4.674 ± 1.494
2.181SerGln: 2.181 ± 0.545
6.232SerArg: 6.232 ± 0.589
6.856SerSer: 6.856 ± 0.348
3.739SerThr: 3.739 ± 0.354
5.609SerVal: 5.609 ± 2.176
1.558SerTrp: 1.558 ± 0.298
2.805SerTyr: 2.805 ± 0.787
0.0SerXaa: 0.0 ± 0.0
Thr
2.805ThrAla: 2.805 ± 0.186
0.623ThrCys: 0.623 ± 0.36
2.181ThrAsp: 2.181 ± 0.545
3.428ThrGlu: 3.428 ± 0.775
0.623ThrPhe: 0.623 ± 0.242
1.246ThrGly: 1.246 ± 0.484
0.312ThrHis: 0.312 ± 0.422
2.493ThrIle: 2.493 ± 0.236
2.805ThrLys: 2.805 ± 0.416
8.102ThrLeu: 8.102 ± 0.136
2.181ThrMet: 2.181 ± 0.347
2.493ThrAsn: 2.493 ± 0.366
4.674ThrPro: 4.674 ± 0.911
1.246ThrGln: 1.246 ± 0.719
2.805ThrArg: 2.805 ± 1.017
6.232ThrSer: 6.232 ± 1.816
2.181ThrThr: 2.181 ± 0.657
2.181ThrVal: 2.181 ± 0.545
0.0ThrTrp: 0.0 ± 0.0
2.805ThrTyr: 2.805 ± 0.787
0.0ThrXaa: 0.0 ± 0.0
Val
9.037ValAla: 9.037 ± 1.005
0.623ValCys: 0.623 ± 0.36
2.805ValAsp: 2.805 ± 0.186
4.051ValGlu: 4.051 ± 0.669
3.116ValPhe: 3.116 ± 1.209
4.986ValGly: 4.986 ± 0.13
2.181ValHis: 2.181 ± 0.056
2.181ValIle: 2.181 ± 0.657
3.739ValLys: 3.739 ± 0.248
4.363ValLeu: 4.363 ± 0.112
0.623ValMet: 0.623 ± 0.36
3.739ValAsn: 3.739 ± 0.849
3.116ValPro: 3.116 ± 0.607
1.87ValGln: 1.87 ± 0.725
2.181ValArg: 2.181 ± 1.748
6.232ValSer: 6.232 ± 0.589
4.986ValThr: 4.986 ± 0.472
5.609ValVal: 5.609 ± 0.23
0.312ValTrp: 0.312 ± 0.18
3.428ValTyr: 3.428 ± 0.428
0.0ValXaa: 0.0 ± 0.0
Trp
1.246TrpAla: 1.246 ± 0.719
0.623TrpCys: 0.623 ± 0.242
0.935TrpAsp: 0.935 ± 0.539
0.312TrpGlu: 0.312 ± 0.422
0.312TrpPhe: 0.312 ± 0.18
0.0TrpGly: 0.0 ± 0.0
0.623TrpHis: 0.623 ± 0.36
0.312TrpIle: 0.312 ± 0.18
0.312TrpLys: 0.312 ± 0.18
1.558TrpLeu: 1.558 ± 0.304
0.935TrpMet: 0.935 ± 0.062
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.312TrpArg: 0.312 ± 0.422
0.312TrpSer: 0.312 ± 0.18
0.623TrpThr: 0.623 ± 0.36
0.312TrpVal: 0.312 ± 0.18
0.312TrpTrp: 0.312 ± 0.18
0.312TrpTyr: 0.312 ± 0.18
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.805TyrAla: 2.805 ± 1.618
0.935TyrCys: 0.935 ± 0.539
1.558TyrAsp: 1.558 ± 0.905
1.246TyrGlu: 1.246 ± 0.484
1.87TyrPhe: 1.87 ± 0.124
2.181TyrGly: 2.181 ± 0.657
0.312TyrHis: 0.312 ± 0.18
2.181TyrIle: 2.181 ± 0.056
1.558TyrLys: 1.558 ± 0.899
3.428TyrLeu: 3.428 ± 0.174
1.246TyrMet: 1.246 ± 0.484
2.805TyrAsn: 2.805 ± 0.186
1.246TyrPro: 1.246 ± 0.118
0.935TyrGln: 0.935 ± 0.062
0.935TyrArg: 0.935 ± 0.062
4.051TyrSer: 4.051 ± 0.068
2.181TyrThr: 2.181 ± 1.748
1.87TyrVal: 1.87 ± 0.124
0.312TyrTrp: 0.312 ± 0.422
0.935TyrTyr: 0.935 ± 0.539
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3210 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski