Amino acid dipepetide frequency for Lentinula edodes negative-strand RNA virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.25AlaAla: 6.25 ± 1.177
1.42AlaCys: 1.42 ± 0.571
3.693AlaAsp: 3.693 ± 0.531
3.693AlaGlu: 3.693 ± 1.933
2.557AlaPhe: 2.557 ± 0.927
4.545AlaGly: 4.545 ± 1.321
3.409AlaHis: 3.409 ± 1.27
2.557AlaIle: 2.557 ± 1.025
3.125AlaLys: 3.125 ± 1.458
9.091AlaLeu: 9.091 ± 1.179
3.693AlaMet: 3.693 ± 1.004
1.989AlaAsn: 1.989 ± 1.44
4.261AlaPro: 4.261 ± 2.155
1.42AlaGln: 1.42 ± 0.749
4.545AlaArg: 4.545 ± 1.065
6.25AlaSer: 6.25 ± 0.747
5.398AlaThr: 5.398 ± 1.966
6.534AlaVal: 6.534 ± 2.172
0.568AlaTrp: 0.568 ± 0.33
1.989AlaTyr: 1.989 ± 0.596
0.0AlaXaa: 0.0 ± 0.0
Cys
1.705CysAla: 1.705 ± 0.66
0.284CysCys: 0.284 ± 0.331
0.568CysAsp: 0.568 ± 0.33
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.136CysGly: 1.136 ± 0.433
0.0CysHis: 0.0 ± 0.0
0.852CysIle: 0.852 ± 0.372
0.568CysLys: 0.568 ± 0.449
1.42CysLeu: 1.42 ± 0.518
0.0CysMet: 0.0 ± 0.0
0.284CysAsn: 0.284 ± 0.165
0.284CysPro: 0.284 ± 0.5
0.0CysGln: 0.0 ± 0.0
1.136CysArg: 1.136 ± 0.526
1.705CysSer: 1.705 ± 0.432
0.284CysThr: 0.284 ± 0.165
1.42CysVal: 1.42 ± 0.825
0.0CysTrp: 0.0 ± 0.0
0.568CysTyr: 0.568 ± 0.33
0.0CysXaa: 0.0 ± 0.0
Asp
3.977AspAla: 3.977 ± 1.314
0.568AspCys: 0.568 ± 0.33
5.114AspAsp: 5.114 ± 1.357
4.545AspGlu: 4.545 ± 0.588
2.557AspPhe: 2.557 ± 0.49
2.273AspGly: 2.273 ± 0.828
0.284AspHis: 0.284 ± 0.165
3.977AspIle: 3.977 ± 1.24
1.136AspLys: 1.136 ± 0.436
5.966AspLeu: 5.966 ± 1.224
1.136AspMet: 1.136 ± 0.581
1.705AspAsn: 1.705 ± 0.526
4.261AspPro: 4.261 ± 0.401
2.841AspGln: 2.841 ± 1.082
4.261AspArg: 4.261 ± 0.617
5.398AspSer: 5.398 ± 0.883
3.693AspThr: 3.693 ± 0.956
3.125AspVal: 3.125 ± 0.802
1.136AspTrp: 1.136 ± 0.66
1.42AspTyr: 1.42 ± 0.518
0.0AspXaa: 0.0 ± 0.0
Glu
4.545GluAla: 4.545 ± 2.116
0.568GluCys: 0.568 ± 0.33
5.114GluAsp: 5.114 ± 1.324
4.83GluGlu: 4.83 ± 1.36
1.705GluPhe: 1.705 ± 0.545
3.409GluGly: 3.409 ± 0.994
1.136GluHis: 1.136 ± 0.66
3.977GluIle: 3.977 ± 1.416
4.545GluLys: 4.545 ± 1.315
4.545GluLeu: 4.545 ± 1.282
1.989GluMet: 1.989 ± 0.761
1.705GluAsn: 1.705 ± 1.067
1.136GluPro: 1.136 ± 0.752
2.557GluGln: 2.557 ± 0.768
2.557GluArg: 2.557 ± 0.69
5.398GluSer: 5.398 ± 1.226
2.841GluThr: 2.841 ± 1.993
3.125GluVal: 3.125 ± 1.844
0.852GluTrp: 0.852 ± 0.809
1.42GluTyr: 1.42 ± 1.118
0.0GluXaa: 0.0 ± 0.0
Phe
1.42PheAla: 1.42 ± 0.614
0.0PheCys: 0.0 ± 0.0
1.705PheAsp: 1.705 ± 0.817
1.705PheGlu: 1.705 ± 0.835
1.705PhePhe: 1.705 ± 0.534
1.989PheGly: 1.989 ± 0.837
1.42PheHis: 1.42 ± 0.571
1.989PheIle: 1.989 ± 0.881
1.42PheLys: 1.42 ± 0.614
3.409PheLeu: 3.409 ± 1.073
0.568PheMet: 0.568 ± 0.807
1.136PheAsn: 1.136 ± 0.645
2.841PhePro: 2.841 ± 0.621
1.42PheGln: 1.42 ± 0.567
1.705PheArg: 1.705 ± 0.529
3.977PheSer: 3.977 ± 0.796
2.273PheThr: 2.273 ± 1.32
1.136PheVal: 1.136 ± 0.556
0.284PheTrp: 0.284 ± 0.503
0.852PheTyr: 0.852 ± 0.454
0.0PheXaa: 0.0 ± 0.0
Gly
4.545GlyAla: 4.545 ± 1.803
0.284GlyCys: 0.284 ± 0.503
4.545GlyAsp: 4.545 ± 1.168
3.977GlyGlu: 3.977 ± 1.307
1.705GlyPhe: 1.705 ± 1.076
4.545GlyGly: 4.545 ± 1.218
0.852GlyHis: 0.852 ± 0.33
4.83GlyIle: 4.83 ± 1.306
1.989GlyLys: 1.989 ± 1.967
5.682GlyLeu: 5.682 ± 1.858
0.568GlyMet: 0.568 ± 0.286
2.273GlyAsn: 2.273 ± 0.478
2.273GlyPro: 2.273 ± 0.866
1.989GlyGln: 1.989 ± 0.615
4.545GlyArg: 4.545 ± 1.262
5.682GlySer: 5.682 ± 2.073
2.841GlyThr: 2.841 ± 0.691
5.114GlyVal: 5.114 ± 2.393
0.852GlyTrp: 0.852 ± 1.047
2.841GlyTyr: 2.841 ± 0.912
0.0GlyXaa: 0.0 ± 0.0
His
1.136HisAla: 1.136 ± 0.629
1.42HisCys: 1.42 ± 0.571
1.705HisAsp: 1.705 ± 0.499
0.568HisGlu: 0.568 ± 0.452
0.0HisPhe: 0.0 ± 0.0
1.989HisGly: 1.989 ± 0.441
0.568HisHis: 0.568 ± 0.33
1.136HisIle: 1.136 ± 0.724
0.568HisLys: 0.568 ± 0.33
2.557HisLeu: 2.557 ± 0.792
0.568HisMet: 0.568 ± 0.33
0.568HisAsn: 0.568 ± 0.602
1.705HisPro: 1.705 ± 0.545
1.42HisGln: 1.42 ± 0.588
2.273HisArg: 2.273 ± 1.32
1.42HisSer: 1.42 ± 0.518
0.568HisThr: 0.568 ± 0.336
0.852HisVal: 0.852 ± 0.365
0.284HisTrp: 0.284 ± 0.165
1.705HisTyr: 1.705 ± 0.99
0.0HisXaa: 0.0 ± 0.0
Ile
1.989IleAla: 1.989 ± 0.786
0.284IleCys: 0.284 ± 0.331
3.409IleAsp: 3.409 ± 1.343
3.409IleGlu: 3.409 ± 0.528
2.273IlePhe: 2.273 ± 1.32
4.545IleGly: 4.545 ± 1.241
1.705IleHis: 1.705 ± 0.99
2.841IleIle: 2.841 ± 0.873
1.136IleLys: 1.136 ± 0.407
6.534IleLeu: 6.534 ± 1.05
0.568IleMet: 0.568 ± 0.33
1.705IleAsn: 1.705 ± 0.954
3.125IlePro: 3.125 ± 0.923
2.273IleGln: 2.273 ± 0.896
5.398IleArg: 5.398 ± 0.605
5.682IleSer: 5.682 ± 1.265
3.693IleThr: 3.693 ± 0.89
4.545IleVal: 4.545 ± 0.931
0.852IleTrp: 0.852 ± 0.33
1.136IleTyr: 1.136 ± 0.665
0.0IleXaa: 0.0 ± 0.0
Lys
4.261LysAla: 4.261 ± 0.842
0.284LysCys: 0.284 ± 0.165
3.125LysAsp: 3.125 ± 0.763
3.409LysGlu: 3.409 ± 0.992
0.852LysPhe: 0.852 ± 0.473
3.693LysGly: 3.693 ± 1.287
0.284LysHis: 0.284 ± 0.165
1.989LysIle: 1.989 ± 0.652
1.42LysLys: 1.42 ± 0.642
3.977LysLeu: 3.977 ± 1.107
1.136LysMet: 1.136 ± 0.436
1.136LysAsn: 1.136 ± 0.436
2.273LysPro: 2.273 ± 0.761
1.136LysGln: 1.136 ± 0.629
2.557LysArg: 2.557 ± 1.328
2.557LysSer: 2.557 ± 0.518
0.852LysThr: 0.852 ± 0.596
2.841LysVal: 2.841 ± 1.943
0.284LysTrp: 0.284 ± 0.331
1.42LysTyr: 1.42 ± 1.052
0.0LysXaa: 0.0 ± 0.0
Leu
10.511LeuAla: 10.511 ± 1.085
0.568LeuCys: 0.568 ± 0.33
5.398LeuAsp: 5.398 ± 0.622
5.966LeuGlu: 5.966 ± 1.352
1.705LeuPhe: 1.705 ± 0.99
7.386LeuGly: 7.386 ± 1.57
1.989LeuHis: 1.989 ± 0.592
4.545LeuIle: 4.545 ± 1.224
3.693LeuLys: 3.693 ± 0.953
9.375LeuLeu: 9.375 ± 1.313
1.989LeuMet: 1.989 ± 0.57
1.989LeuAsn: 1.989 ± 0.875
6.818LeuPro: 6.818 ± 1.667
4.545LeuGln: 4.545 ± 1.043
7.955LeuArg: 7.955 ± 1.268
10.795LeuSer: 10.795 ± 0.832
7.386LeuThr: 7.386 ± 2.602
6.25LeuVal: 6.25 ± 1.401
0.852LeuTrp: 0.852 ± 0.495
2.273LeuTyr: 2.273 ± 0.956
0.0LeuXaa: 0.0 ± 0.0
Met
1.705MetAla: 1.705 ± 1.289
0.0MetCys: 0.0 ± 0.0
1.136MetAsp: 1.136 ± 0.72
0.284MetGlu: 0.284 ± 0.331
1.705MetPhe: 1.705 ± 0.99
1.136MetGly: 1.136 ± 0.573
0.284MetHis: 0.284 ± 0.34
0.852MetIle: 0.852 ± 0.365
1.42MetLys: 1.42 ± 0.649
3.125MetLeu: 3.125 ± 0.833
1.136MetMet: 1.136 ± 0.436
0.0MetAsn: 0.0 ± 0.0
0.284MetPro: 0.284 ± 0.331
0.852MetGln: 0.852 ± 0.332
2.557MetArg: 2.557 ± 0.92
2.273MetSer: 2.273 ± 0.614
0.852MetThr: 0.852 ± 0.856
2.557MetVal: 2.557 ± 0.608
0.0MetTrp: 0.0 ± 0.0
0.852MetTyr: 0.852 ± 0.495
0.0MetXaa: 0.0 ± 0.0
Asn
1.989AsnAla: 1.989 ± 1.027
0.284AsnCys: 0.284 ± 0.165
1.705AsnAsp: 1.705 ± 0.432
1.136AsnGlu: 1.136 ± 0.42
0.284AsnPhe: 0.284 ± 0.413
1.42AsnGly: 1.42 ± 1.732
1.42AsnHis: 1.42 ± 0.825
1.989AsnIle: 1.989 ± 0.815
1.136AsnLys: 1.136 ± 0.598
3.125AsnLeu: 3.125 ± 0.898
1.42AsnMet: 1.42 ± 1.019
0.852AsnAsn: 0.852 ± 0.935
0.852AsnPro: 0.852 ± 0.372
0.852AsnGln: 0.852 ± 0.991
1.136AsnArg: 1.136 ± 0.403
1.136AsnSer: 1.136 ± 0.598
0.568AsnThr: 0.568 ± 0.463
1.136AsnVal: 1.136 ± 0.786
0.852AsnTrp: 0.852 ± 0.496
0.284AsnTyr: 0.284 ± 0.331
0.0AsnXaa: 0.0 ± 0.0
Pro
5.114ProAla: 5.114 ± 2.302
0.568ProCys: 0.568 ± 0.33
2.557ProAsp: 2.557 ± 0.706
3.125ProGlu: 3.125 ± 0.495
2.841ProPhe: 2.841 ± 0.504
3.125ProGly: 3.125 ± 2.561
0.852ProHis: 0.852 ± 0.619
2.557ProIle: 2.557 ± 0.866
2.273ProLys: 2.273 ± 0.489
3.977ProLeu: 3.977 ± 0.818
0.852ProMet: 0.852 ± 0.455
1.705ProAsn: 1.705 ± 1.215
6.25ProPro: 6.25 ± 2.906
1.705ProGln: 1.705 ± 0.631
2.841ProArg: 2.841 ± 0.72
4.83ProSer: 4.83 ± 1.822
4.261ProThr: 4.261 ± 0.834
4.545ProVal: 4.545 ± 1.679
0.852ProTrp: 0.852 ± 0.495
2.557ProTyr: 2.557 ± 0.854
0.0ProXaa: 0.0 ± 0.0
Gln
3.125GlnAla: 3.125 ± 1.306
0.284GlnCys: 0.284 ± 0.165
1.989GlnAsp: 1.989 ± 1.103
3.693GlnGlu: 3.693 ± 1.7
1.136GlnPhe: 1.136 ± 0.389
2.841GlnGly: 2.841 ± 0.62
0.284GlnHis: 0.284 ± 0.165
1.705GlnIle: 1.705 ± 0.447
1.989GlnLys: 1.989 ± 0.756
4.545GlnLeu: 4.545 ± 1.648
0.568GlnMet: 0.568 ± 0.33
0.284GlnAsn: 0.284 ± 0.475
1.989GlnPro: 1.989 ± 0.939
0.852GlnGln: 0.852 ± 0.596
2.841GlnArg: 2.841 ± 0.792
1.705GlnSer: 1.705 ± 0.633
3.409GlnThr: 3.409 ± 0.915
1.989GlnVal: 1.989 ± 0.874
0.0GlnTrp: 0.0 ± 0.0
1.136GlnTyr: 1.136 ± 0.436
0.0GlnXaa: 0.0 ± 0.0
Arg
4.261ArgAla: 4.261 ± 1.327
2.273ArgCys: 2.273 ± 1.351
5.114ArgAsp: 5.114 ± 1.12
3.409ArgGlu: 3.409 ± 0.823
2.557ArgPhe: 2.557 ± 0.866
4.261ArgGly: 4.261 ± 0.958
1.989ArgHis: 1.989 ± 1.077
3.409ArgIle: 3.409 ± 0.963
1.989ArgLys: 1.989 ± 0.833
7.955ArgLeu: 7.955 ± 2.298
2.273ArgMet: 2.273 ± 1.03
0.284ArgAsn: 0.284 ± 0.475
3.125ArgPro: 3.125 ± 0.573
4.261ArgGln: 4.261 ± 1.878
4.545ArgArg: 4.545 ± 1.377
5.682ArgSer: 5.682 ± 1.593
3.409ArgThr: 3.409 ± 0.885
6.25ArgVal: 6.25 ± 0.978
2.841ArgTrp: 2.841 ± 1.256
2.557ArgTyr: 2.557 ± 1.146
0.0ArgXaa: 0.0 ± 0.0
Ser
4.83SerAla: 4.83 ± 0.868
0.852SerCys: 0.852 ± 0.495
4.261SerAsp: 4.261 ± 1.707
2.557SerGlu: 2.557 ± 0.75
4.545SerPhe: 4.545 ± 1.7
5.398SerGly: 5.398 ± 1.218
2.557SerHis: 2.557 ± 0.556
5.682SerIle: 5.682 ± 2.604
4.83SerLys: 4.83 ± 0.689
10.227SerLeu: 10.227 ± 2.621
1.705SerMet: 1.705 ± 0.432
1.705SerAsn: 1.705 ± 1.229
6.25SerPro: 6.25 ± 1.662
3.125SerGln: 3.125 ± 1.089
6.818SerArg: 6.818 ± 1.655
9.091SerSer: 9.091 ± 0.953
4.83SerThr: 4.83 ± 1.046
6.25SerVal: 6.25 ± 1.968
1.705SerTrp: 1.705 ± 0.432
4.261SerTyr: 4.261 ± 2.121
0.0SerXaa: 0.0 ± 0.0
Thr
4.261ThrAla: 4.261 ± 1.065
0.568ThrCys: 0.568 ± 0.33
2.557ThrAsp: 2.557 ± 1.485
4.545ThrGlu: 4.545 ± 2.484
1.42ThrPhe: 1.42 ± 0.596
2.841ThrGly: 2.841 ± 0.873
1.42ThrHis: 1.42 ± 0.48
5.114ThrIle: 5.114 ± 0.514
1.136ThrLys: 1.136 ± 0.629
5.682ThrLeu: 5.682 ± 1.223
0.568ThrMet: 0.568 ± 0.286
1.136ThrAsn: 1.136 ± 0.705
3.693ThrPro: 3.693 ± 0.763
1.136ThrGln: 1.136 ± 0.645
4.261ThrArg: 4.261 ± 1.704
5.682ThrSer: 5.682 ± 1.203
4.545ThrThr: 4.545 ± 1.768
4.83ThrVal: 4.83 ± 1.162
0.852ThrTrp: 0.852 ± 0.532
1.705ThrTyr: 1.705 ± 0.529
0.0ThrXaa: 0.0 ± 0.0
Val
8.523ValAla: 8.523 ± 1.568
0.568ValCys: 0.568 ± 0.393
4.261ValAsp: 4.261 ± 0.786
4.545ValGlu: 4.545 ± 1.425
2.273ValPhe: 2.273 ± 0.651
3.125ValGly: 3.125 ± 1.288
1.136ValHis: 1.136 ± 0.436
5.114ValIle: 5.114 ± 0.912
3.977ValLys: 3.977 ± 0.748
6.534ValLeu: 6.534 ± 0.744
1.136ValMet: 1.136 ± 0.575
1.136ValAsn: 1.136 ± 0.703
3.125ValPro: 3.125 ± 0.648
2.557ValGln: 2.557 ± 0.847
5.398ValArg: 5.398 ± 1.864
7.102ValSer: 7.102 ± 1.969
3.409ValThr: 3.409 ± 0.619
4.545ValVal: 4.545 ± 1.172
0.284ValTrp: 0.284 ± 0.165
0.852ValTyr: 0.852 ± 0.495
0.0ValXaa: 0.0 ± 0.0
Trp
1.136TrpAla: 1.136 ± 0.42
0.568TrpCys: 0.568 ± 0.286
0.568TrpAsp: 0.568 ± 0.463
0.852TrpGlu: 0.852 ± 0.495
0.284TrpPhe: 0.284 ± 0.5
0.852TrpGly: 0.852 ± 0.454
0.284TrpHis: 0.284 ± 0.331
0.284TrpIle: 0.284 ± 0.165
0.568TrpLys: 0.568 ± 0.602
0.852TrpLeu: 0.852 ± 0.495
0.0TrpMet: 0.0 ± 0.0
0.568TrpAsn: 0.568 ± 0.33
0.284TrpPro: 0.284 ± 0.165
0.284TrpGln: 0.284 ± 0.165
1.705TrpArg: 1.705 ± 1.379
1.136TrpSer: 1.136 ± 0.66
1.136TrpThr: 1.136 ± 0.436
1.136TrpVal: 1.136 ± 0.991
0.284TrpTrp: 0.284 ± 0.165
0.852TrpTyr: 0.852 ± 0.495
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.989TyrAla: 1.989 ± 0.825
0.568TyrCys: 0.568 ± 0.33
0.852TyrAsp: 0.852 ± 0.332
1.705TyrGlu: 1.705 ± 0.447
0.852TyrPhe: 0.852 ± 0.33
1.42TyrGly: 1.42 ± 0.825
1.136TyrHis: 1.136 ± 0.66
1.705TyrIle: 1.705 ± 0.753
0.568TyrLys: 0.568 ± 0.336
3.409TyrLeu: 3.409 ± 1.127
0.852TyrMet: 0.852 ± 0.332
1.42TyrAsn: 1.42 ± 0.571
2.557TyrPro: 2.557 ± 0.766
1.136TyrGln: 1.136 ± 0.433
3.409TyrArg: 3.409 ± 1.674
3.977TyrSer: 3.977 ± 1.31
1.705TyrThr: 1.705 ± 0.458
1.42TyrVal: 1.42 ± 0.437
0.0TyrTrp: 0.0 ± 0.0
0.852TyrTyr: 0.852 ± 0.33
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (3521 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski