Amino acid dipepetide frequency for Stereum hirsutum (strain FP-91666) (White-rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.621AlaAla: 7.621 ± 0.163	1.183AlaCys: 1.183 ± 0.047	4.036AlaAsp: 4.036 ± 0.08	4.556AlaGlu: 4.556 ± 0.105	3.135AlaPhe: 3.135 ± 0.072	5.208AlaGly: 5.208 ± 0.108	2.143AlaHis: 2.143 ± 0.06	3.98AlaIle: 3.98 ± 0.096	3.519AlaLys: 3.519 ± 0.079	8.028AlaLeu: 8.028 ± 0.124	1.926AlaMet: 1.926 ± 0.056	2.789AlaAsn: 2.789 ± 0.058	5.238AlaPro: 5.238 ± 0.107	3.146AlaGln: 3.146 ± 0.068	4.993AlaArg: 4.993 ± 0.09	7.521AlaSer: 7.521 ± 0.129	5.339AlaThr: 5.339 ± 0.107	5.384AlaVal: 5.384 ± 0.091	1.214AlaTrp: 1.214 ± 0.043	2.217AlaTyr: 2.217 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.079CysAla: 1.079 ± 0.04	0.243CysCys: 0.243 ± 0.019	0.69CysAsp: 0.69 ± 0.035	0.646CysGlu: 0.646 ± 0.031	0.555CysPhe: 0.555 ± 0.027	0.942CysGly: 0.942 ± 0.046	0.339CysHis: 0.339 ± 0.025	0.742CysIle: 0.742 ± 0.032	0.535CysLys: 0.535 ± 0.031	1.263CysLeu: 1.263 ± 0.046	0.306CysMet: 0.306 ± 0.022	0.373CysAsn: 0.373 ± 0.023	0.793CysPro: 0.793 ± 0.044	0.436CysGln: 0.436 ± 0.027	0.851CysArg: 0.851 ± 0.035	1.177CysSer: 1.177 ± 0.046	0.813CysThr: 0.813 ± 0.033	0.854CysVal: 0.854 ± 0.034	0.241CysTrp: 0.241 ± 0.02	0.33CysTyr: 0.33 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	4.754AspAla: 4.754 ± 0.088	0.663AspCys: 0.663 ± 0.031	4.381AspAsp: 4.381 ± 0.088	4.61AspGlu: 4.61 ± 0.12	2.117AspPhe: 2.117 ± 0.059	4.422AspGly: 4.422 ± 0.091	1.335AspHis: 1.335 ± 0.047	3.075AspIle: 3.075 ± 0.074	1.989AspLys: 1.989 ± 0.052	4.735AspLeu: 4.735 ± 0.088	1.163AspMet: 1.163 ± 0.043	1.724AspAsn: 1.724 ± 0.056	3.384AspPro: 3.384 ± 0.077	1.624AspGln: 1.624 ± 0.056	3.014AspArg: 3.014 ± 0.079	4.2AspSer: 4.2 ± 0.087	3.091AspThr: 3.091 ± 0.073	4.178AspVal: 4.178 ± 0.065	0.955AspTrp: 0.955 ± 0.038	1.418AspTyr: 1.418 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	4.883GluAla: 4.883 ± 0.1	0.742GluCys: 0.742 ± 0.038	4.267GluAsp: 4.267 ± 0.113	5.443GluGlu: 5.443 ± 0.137	1.882GluPhe: 1.882 ± 0.05	4.177GluGly: 4.177 ± 0.1	1.432GluHis: 1.432 ± 0.053	2.611GluIle: 2.611 ± 0.055	2.977GluLys: 2.977 ± 0.083	5.008GluLeu: 5.008 ± 0.098	1.54GluMet: 1.54 ± 0.054	1.925GluAsn: 1.925 ± 0.049	2.799GluPro: 2.799 ± 0.067	2.003GluGln: 2.003 ± 0.056	4.469GluArg: 4.469 ± 0.123	3.986GluSer: 3.986 ± 0.085	3.281GluThr: 3.281 ± 0.076	3.766GluVal: 3.766 ± 0.077	1.062GluTrp: 1.062 ± 0.041	1.538GluTyr: 1.538 ± 0.054	0.0GluXaa: 0.0 ± 0.0
Phe	2.907PheAla: 2.907 ± 0.073	0.564PheCys: 0.564 ± 0.027	2.208PheAsp: 2.208 ± 0.055	2.162PheGlu: 2.162 ± 0.06	1.51PhePhe: 1.51 ± 0.054	2.675PheGly: 2.675 ± 0.077	0.96PheHis: 0.96 ± 0.044	1.727PheIle: 1.727 ± 0.06	1.401PheLys: 1.401 ± 0.05	3.485PheLeu: 3.485 ± 0.073	0.786PheMet: 0.786 ± 0.028	1.277PheAsn: 1.277 ± 0.043	2.016PhePro: 2.016 ± 0.053	1.072PheGln: 1.072 ± 0.039	1.885PheArg: 1.885 ± 0.061	3.189PheSer: 3.189 ± 0.086	2.264PheThr: 2.264 ± 0.071	2.497PheVal: 2.497 ± 0.066	0.552PheTrp: 0.552 ± 0.029	1.109PheTyr: 1.109 ± 0.043	0.0PheXaa: 0.0 ± 0.0
Gly	5.181GlyAla: 5.181 ± 0.103	0.89GlyCys: 0.89 ± 0.038	3.687GlyAsp: 3.687 ± 0.082	4.026GlyGlu: 4.026 ± 0.085	2.436GlyPhe: 2.436 ± 0.062	6.288GlyGly: 6.288 ± 0.244	1.94GlyHis: 1.94 ± 0.07	3.032GlyIle: 3.032 ± 0.083	3.111GlyLys: 3.111 ± 0.074	5.582GlyLeu: 5.582 ± 0.098	1.715GlyMet: 1.715 ± 0.058	2.269GlyAsn: 2.269 ± 0.067	3.455GlyPro: 3.455 ± 0.091	2.238GlyGln: 2.238 ± 0.079	4.228GlyArg: 4.228 ± 0.09	5.988GlySer: 5.988 ± 0.131	4.049GlyThr: 4.049 ± 0.093	4.252GlyVal: 4.252 ± 0.082	1.219GlyTrp: 1.219 ± 0.046	1.831GlyTyr: 1.831 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.154HisAla: 2.154 ± 0.06	0.396HisCys: 0.396 ± 0.023	1.481HisAsp: 1.481 ± 0.043	1.27HisGlu: 1.27 ± 0.047	0.988HisPhe: 0.988 ± 0.039	1.812HisGly: 1.812 ± 0.062	1.052HisHis: 1.052 ± 0.055	1.438HisIle: 1.438 ± 0.051	0.897HisLys: 0.897 ± 0.038	2.648HisLeu: 2.648 ± 0.07	0.426HisMet: 0.426 ± 0.024	0.881HisAsn: 0.881 ± 0.037	2.127HisPro: 2.127 ± 0.074	0.974HisGln: 0.974 ± 0.041	1.751HisArg: 1.751 ± 0.055	2.339HisSer: 2.339 ± 0.055	1.678HisThr: 1.678 ± 0.051	1.676HisVal: 1.676 ± 0.055	0.343HisTrp: 0.343 ± 0.02	0.639HisTyr: 0.639 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	3.98IleAla: 3.98 ± 0.089	0.76IleCys: 0.76 ± 0.033	2.792IleAsp: 2.792 ± 0.062	2.607IleGlu: 2.607 ± 0.058	1.915IlePhe: 1.915 ± 0.058	2.903IleGly: 2.903 ± 0.079	1.233IleHis: 1.233 ± 0.051	2.393IleIle: 2.393 ± 0.07	1.817IleLys: 1.817 ± 0.055	4.316IleLeu: 4.316 ± 0.086	0.914IleMet: 0.914 ± 0.039	1.395IleAsn: 1.395 ± 0.052	3.522IlePro: 3.522 ± 0.069	1.664IleGln: 1.664 ± 0.053	2.829IleArg: 2.829 ± 0.076	3.955IleSer: 3.955 ± 0.08	2.736IleThr: 2.736 ± 0.069	3.404IleVal: 3.404 ± 0.085	0.773IleTrp: 0.773 ± 0.039	1.217IleTyr: 1.217 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	3.758LysAla: 3.758 ± 0.088	0.54LysCys: 0.54 ± 0.026	2.373LysAsp: 2.373 ± 0.06	2.995LysGlu: 2.995 ± 0.08	1.206LysPhe: 1.206 ± 0.044	2.726LysGly: 2.726 ± 0.072	1.028LysHis: 1.028 ± 0.04	1.835LysIle: 1.835 ± 0.045	2.632LysLys: 2.632 ± 0.089	3.262LysLeu: 3.262 ± 0.072	0.85LysMet: 0.85 ± 0.036	1.422LysAsn: 1.422 ± 0.048	2.299LysPro: 2.299 ± 0.059	1.323LysGln: 1.323 ± 0.049	3.383LysArg: 3.383 ± 0.088	2.983LysSer: 2.983 ± 0.071	2.432LysThr: 2.432 ± 0.06	2.501LysVal: 2.501 ± 0.074	0.673LysTrp: 0.673 ± 0.035	1.116LysTyr: 1.116 ± 0.047	0.0LysXaa: 0.0 ± 0.0
Leu	7.44LeuAla: 7.44 ± 0.123	1.318LeuCys: 1.318 ± 0.047	5.044LeuAsp: 5.044 ± 0.092	5.149LeuGlu: 5.149 ± 0.098	3.33LeuPhe: 3.33 ± 0.091	5.462LeuGly: 5.462 ± 0.105	2.615LeuHis: 2.615 ± 0.069	3.751LeuIle: 3.751 ± 0.09	3.595LeuLys: 3.595 ± 0.082	8.175LeuLeu: 8.175 ± 0.148	1.794LeuMet: 1.794 ± 0.058	2.981LeuAsn: 2.981 ± 0.075	6.106LeuPro: 6.106 ± 0.104	3.334LeuGln: 3.334 ± 0.079	6.154LeuArg: 6.154 ± 0.117	8.424LeuSer: 8.424 ± 0.14	5.306LeuThr: 5.306 ± 0.094	5.307LeuVal: 5.307 ± 0.104	1.283LeuTrp: 1.283 ± 0.043	2.34LeuTyr: 2.34 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	1.848MetAla: 1.848 ± 0.059	0.295MetCys: 0.295 ± 0.022	1.28MetAsp: 1.28 ± 0.044	1.209MetGlu: 1.209 ± 0.039	0.807MetPhe: 0.807 ± 0.04	1.375MetGly: 1.375 ± 0.055	0.518MetHis: 0.518 ± 0.027	0.957MetIle: 0.957 ± 0.035	1.012MetLys: 1.012 ± 0.041	1.778MetLeu: 1.778 ± 0.06	0.575MetMet: 0.575 ± 0.029	0.715MetAsn: 0.715 ± 0.033	1.227MetPro: 1.227 ± 0.046	0.787MetGln: 0.787 ± 0.035	1.303MetArg: 1.303 ± 0.05	2.135MetSer: 2.135 ± 0.057	1.247MetThr: 1.247 ± 0.047	1.328MetVal: 1.328 ± 0.052	0.295MetTrp: 0.295 ± 0.021	0.547MetTyr: 0.547 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	3.025AsnAla: 3.025 ± 0.068	0.364AsnCys: 0.364 ± 0.029	1.842AsnAsp: 1.842 ± 0.055	1.751AsnGlu: 1.751 ± 0.049	1.109AsnPhe: 1.109 ± 0.036	2.797AsnGly: 2.797 ± 0.085	0.839AsnHis: 0.839 ± 0.036	1.965AsnIle: 1.965 ± 0.054	1.194AsnLys: 1.194 ± 0.038	3.045AsnLeu: 3.045 ± 0.064	0.733AsnMet: 0.733 ± 0.031	1.311AsnAsn: 1.311 ± 0.065	2.221AsnPro: 2.221 ± 0.062	1.046AsnGln: 1.046 ± 0.042	1.777AsnArg: 1.777 ± 0.05	2.813AsnSer: 2.813 ± 0.075	2.205AsnThr: 2.205 ± 0.063	2.285AsnVal: 2.285 ± 0.056	0.473AsnTrp: 0.473 ± 0.026	0.802AsnTyr: 0.802 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	5.195ProAla: 5.195 ± 0.113	0.551ProCys: 0.551 ± 0.031	3.404ProAsp: 3.404 ± 0.075	3.627ProGlu: 3.627 ± 0.082	2.246ProPhe: 2.246 ± 0.062	3.626ProGly: 3.626 ± 0.091	2.007ProHis: 2.007 ± 0.068	2.866ProIle: 2.866 ± 0.064	2.328ProLys: 2.328 ± 0.065	5.249ProLeu: 5.249 ± 0.104	1.034ProMet: 1.034 ± 0.042	2.259ProAsn: 2.259 ± 0.07	6.442ProPro: 6.442 ± 0.268	2.356ProGln: 2.356 ± 0.086	3.699ProArg: 3.699 ± 0.093	8.244ProSer: 8.244 ± 0.17	4.578ProThr: 4.578 ± 0.102	3.728ProVal: 3.728 ± 0.075	0.766ProTrp: 0.766 ± 0.041	1.576ProTyr: 1.576 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	3.092GlnAla: 3.092 ± 0.075	0.483GlnCys: 0.483 ± 0.023	1.721GlnAsp: 1.721 ± 0.051	1.932GlnGlu: 1.932 ± 0.05	1.212GlnPhe: 1.212 ± 0.043	2.064GlnGly: 2.064 ± 0.073	1.058GlnHis: 1.058 ± 0.047	1.466GlnIle: 1.466 ± 0.05	1.417GlnLys: 1.417 ± 0.055	3.2GlnLeu: 3.2 ± 0.071	0.735GlnMet: 0.735 ± 0.036	1.19GlnAsn: 1.19 ± 0.051	2.316GlnPro: 2.316 ± 0.075	1.97GlnGln: 1.97 ± 0.128	2.358GlnArg: 2.358 ± 0.062	3.089GlnSer: 3.089 ± 0.077	2.246GlnThr: 2.246 ± 0.066	1.906GlnVal: 1.906 ± 0.056	0.612GlnTrp: 0.612 ± 0.032	0.995GlnTyr: 0.995 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	4.924ArgAla: 4.924 ± 0.092	0.893ArgCys: 0.893 ± 0.036	3.421ArgAsp: 3.421 ± 0.079	3.99ArgGlu: 3.99 ± 0.135	2.13ArgPhe: 2.13 ± 0.063	3.858ArgGly: 3.858 ± 0.091	1.673ArgHis: 1.673 ± 0.053	2.975ArgIle: 2.975 ± 0.07	3.032ArgLys: 3.032 ± 0.069	5.75ArgLeu: 5.75 ± 0.097	1.469ArgMet: 1.469 ± 0.049	2.161ArgAsn: 2.161 ± 0.057	3.908ArgPro: 3.908 ± 0.102	2.191ArgGln: 2.191 ± 0.071	5.238ArgArg: 5.238 ± 0.131	5.154ArgSer: 5.154 ± 0.09	3.933ArgThr: 3.933 ± 0.091	3.711ArgVal: 3.711 ± 0.071	1.098ArgTrp: 1.098 ± 0.045	1.734ArgTyr: 1.734 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	7.335SerAla: 7.335 ± 0.13	1.025SerCys: 1.025 ± 0.048	4.657SerAsp: 4.657 ± 0.09	4.356SerGlu: 4.356 ± 0.088	3.313SerPhe: 3.313 ± 0.075	6.019SerGly: 6.019 ± 0.12	2.414SerHis: 2.414 ± 0.06	4.18SerIle: 4.18 ± 0.081	3.199SerLys: 3.199 ± 0.077	7.924SerLeu: 7.924 ± 0.117	1.787SerMet: 1.787 ± 0.048	3.029SerAsn: 3.029 ± 0.082	6.801SerPro: 6.801 ± 0.164	3.18SerGln: 3.18 ± 0.088	5.296SerArg: 5.296 ± 0.118	11.719SerSer: 11.719 ± 0.278	7.137SerThr: 7.137 ± 0.137	5.257SerVal: 5.257 ± 0.104	1.25SerTrp: 1.25 ± 0.045	2.144SerTyr: 2.144 ± 0.067	0.0SerXaa: 0.0 ± 0.0
Thr	5.188ThrAla: 5.188 ± 0.098	0.747ThrCys: 0.747 ± 0.034	2.881ThrAsp: 2.881 ± 0.062	2.967ThrGlu: 2.967 ± 0.073	2.437ThrPhe: 2.437 ± 0.066	4.027ThrGly: 4.027 ± 0.096	1.671ThrHis: 1.671 ± 0.053	3.076ThrIle: 3.076 ± 0.07	2.303ThrLys: 2.303 ± 0.071	5.827ThrLeu: 5.827 ± 0.109	1.237ThrMet: 1.237 ± 0.043	2.266ThrAsn: 2.266 ± 0.069	4.9ThrPro: 4.9 ± 0.115	1.929ThrGln: 1.929 ± 0.06	3.559ThrArg: 3.559 ± 0.087	6.846ThrSer: 6.846 ± 0.133	4.718ThrThr: 4.718 ± 0.109	4.097ThrVal: 4.097 ± 0.083	0.783ThrTrp: 0.783 ± 0.035	1.674ThrTyr: 1.674 ± 0.056	0.0ThrXaa: 0.0 ± 0.0
Val	5.344ValAla: 5.344 ± 0.09	0.903ValCys: 0.903 ± 0.037	3.959ValAsp: 3.959 ± 0.079	4.157ValGlu: 4.157 ± 0.09	2.329ValPhe: 2.329 ± 0.065	4.117ValGly: 4.117 ± 0.098	1.646ValHis: 1.646 ± 0.041	2.87ValIle: 2.87 ± 0.076	2.665ValLys: 2.665 ± 0.072	5.857ValLeu: 5.857 ± 0.108	1.345ValMet: 1.345 ± 0.046	2.128ValAsn: 2.128 ± 0.064	3.908ValPro: 3.908 ± 0.075	2.429ValGln: 2.429 ± 0.068	3.748ValArg: 3.748 ± 0.081	5.051ValSer: 5.051 ± 0.1	3.454ValThr: 3.454 ± 0.097	4.677ValVal: 4.677 ± 0.113	1.008ValTrp: 1.008 ± 0.043	1.727ValTyr: 1.727 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	1.217TrpAla: 1.217 ± 0.047	0.235TrpCys: 0.235 ± 0.018	1.065TrpAsp: 1.065 ± 0.05	0.887TrpGlu: 0.887 ± 0.043	0.559TrpPhe: 0.559 ± 0.03	0.917TrpGly: 0.917 ± 0.038	0.317TrpHis: 0.317 ± 0.022	0.826TrpIle: 0.826 ± 0.039	0.787TrpLys: 0.787 ± 0.037	1.398TrpLeu: 1.398 ± 0.057	0.396TrpMet: 0.396 ± 0.025	0.598TrpAsn: 0.598 ± 0.03	0.7TrpPro: 0.7 ± 0.034	0.497TrpGln: 0.497 ± 0.027	1.112TrpArg: 1.112 ± 0.042	1.163TrpSer: 1.163 ± 0.046	0.979TrpThr: 0.979 ± 0.044	0.957TrpVal: 0.957 ± 0.042	0.289TrpTrp: 0.289 ± 0.02	0.426TrpTyr: 0.426 ± 0.028	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.249TyrAla: 2.249 ± 0.058	0.416TyrCys: 0.416 ± 0.027	1.643TyrAsp: 1.643 ± 0.056	1.449TyrGlu: 1.449 ± 0.049	1.029TyrPhe: 1.029 ± 0.043	2.0TyrGly: 2.0 ± 0.066	0.75TyrHis: 0.75 ± 0.032	1.36TyrIle: 1.36 ± 0.045	0.927TyrLys: 0.927 ± 0.037	2.379TyrLeu: 2.379 ± 0.056	0.505TyrMet: 0.505 ± 0.027	0.903TyrAsn: 0.903 ± 0.035	1.62TyrPro: 1.62 ± 0.05	0.863TyrGln: 0.863 ± 0.035	1.599TyrArg: 1.599 ± 0.049	2.046TyrSer: 2.046 ± 0.056	1.65TyrThr: 1.65 ± 0.051	1.555TyrVal: 1.555 ± 0.057	0.437TyrTrp: 0.437 ± 0.023	0.883TyrTyr: 0.883 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 1613 proteins (702429 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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