Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human B lymphotropic virus)

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus; Human betaherpesvirus 6B

Average proteome isoelectric point is 6.98

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 99 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q9QJ42|U24_HHV6Z U24 protein OS=Human herpesvirus 6B (strain Z29) OX=36351 GN=U24 PE=1 SV=1
MM1 pKa = 7.46LLISKK6 pKa = 7.57TLFPIPRR13 pKa = 11.84SAEE16 pKa = 4.02EE17 pKa = 4.04LWEE20 pKa = 4.18GTYY23 pKa = 10.14TLVVAFVLAFLVYY36 pKa = 10.43SDD38 pKa = 4.32YY39 pKa = 11.47LSNLSPFGEE48 pKa = 4.32ILSSPCISTT57 pKa = 3.6

Molecular weight: 6.34 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q9QJ11|GQ1_HHV6Z Glycoprotein Q1 OS=Human herpesvirus 6B (strain Z29) OX=36351 GN=U100 PE=1 SV=2
MM1 pKa = 6.81QRR3 pKa = 11.84SSACMGISVPTRR15 pKa = 11.84AQTDD19 pKa = 3.82LPKK22 pKa = 10.27QRR24 pKa = 11.84SSACMGISVPARR36 pKa = 11.84AQSDD40 pKa = 3.97LPKK43 pKa = 10.12QKK45 pKa = 10.69SSACMGISVPARR57 pKa = 11.84AQSDD61 pKa = 3.89LPKK64 pKa = 10.12QRR66 pKa = 11.84KK67 pKa = 6.96QRR69 pKa = 11.84LYY71 pKa = 11.14GNKK74 pKa = 9.89CPGPSAAQLPGADD87 pKa = 3.29RR88 pKa = 11.84QRR90 pKa = 11.84LYY92 pKa = 10.37EE93 pKa = 4.18KK94 pKa = 10.05KK95 pKa = 8.84WPGRR99 pKa = 11.84SAVQPAGG106 pKa = 3.34

Molecular weight: 11.37 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

98

1

99

43936

57

2077

443.8

50.57

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.167 ± 0.146

2.504 ± 0.16

4.98 ± 0.129

5.811 ± 0.148

5.33 ± 0.193

4.247 ± 0.247

2.536 ± 0.1

6.566 ± 0.245

6.261 ± 0.23

10.087 ± 0.332

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.467 ± 0.113

5.451 ± 0.243

4.334 ± 0.189

3.605 ± 0.16

5.185 ± 0.278

8.355 ± 0.401

6.396 ± 0.276

6.257 ± 0.267

0.901 ± 0.076

3.551 ± 0.118
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski