Amino acid dipepetide frequency for Actinidia virus B

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.556AlaAla: 3.556 ± 2.084
1.58AlaCys: 1.58 ± 0.581
2.766AlaAsp: 2.766 ± 1.027
3.951AlaGlu: 3.951 ± 0.509
1.976AlaPhe: 1.976 ± 0.688
2.766AlaGly: 2.766 ± 1.034
1.185AlaHis: 1.185 ± 0.631
3.951AlaIle: 3.951 ± 2.713
5.531AlaLys: 5.531 ± 1.31
5.531AlaLeu: 5.531 ± 1.669
0.395AlaMet: 0.395 ± 0.607
1.58AlaAsn: 1.58 ± 1.108
1.185AlaPro: 1.185 ± 0.561
1.976AlaGln: 1.976 ± 0.676
4.741AlaArg: 4.741 ± 0.668
3.556AlaSer: 3.556 ± 1.048
4.346AlaThr: 4.346 ± 3.601
4.741AlaVal: 4.741 ± 1.382
0.0AlaTrp: 0.0 ± 0.0
1.976AlaTyr: 1.976 ± 0.984
0.0AlaXaa: 0.0 ± 0.0
Cys
0.79CysAla: 0.79 ± 0.42
0.79CysCys: 0.79 ± 0.42
1.58CysAsp: 1.58 ± 2.013
1.58CysGlu: 1.58 ± 1.385
0.395CysPhe: 0.395 ± 0.21
1.976CysGly: 1.976 ± 1.028
0.395CysHis: 0.395 ± 0.21
0.395CysIle: 0.395 ± 0.607
1.185CysLys: 1.185 ± 1.045
1.976CysLeu: 1.976 ± 1.3
0.79CysMet: 0.79 ± 0.512
0.79CysAsn: 0.79 ± 0.42
0.395CysPro: 0.395 ± 0.21
0.395CysGln: 0.395 ± 0.21
0.395CysArg: 0.395 ± 1.218
0.79CysSer: 0.79 ± 0.512
0.79CysThr: 0.79 ± 0.42
1.976CysVal: 1.976 ± 2.949
0.0CysTrp: 0.0 ± 0.0
2.371CysTyr: 2.371 ± 1.082
0.0CysXaa: 0.0 ± 0.0
Asp
3.556AspAla: 3.556 ± 1.965
0.395AspCys: 0.395 ± 1.218
3.161AspAsp: 3.161 ± 1.241
5.927AspGlu: 5.927 ± 0.915
2.766AspPhe: 2.766 ± 1.034
3.951AspGly: 3.951 ± 1.523
0.79AspHis: 0.79 ± 0.42
2.371AspIle: 2.371 ± 1.258
3.161AspLys: 3.161 ± 0.759
5.927AspLeu: 5.927 ± 0.883
1.58AspMet: 1.58 ± 0.809
1.58AspAsn: 1.58 ± 0.841
2.766AspPro: 2.766 ± 1.471
2.371AspGln: 2.371 ± 0.988
5.531AspArg: 5.531 ± 1.883
3.951AspSer: 3.951 ± 2.195
1.58AspThr: 1.58 ± 0.561
4.346AspVal: 4.346 ± 0.985
1.185AspTrp: 1.185 ± 0.631
2.371AspTyr: 2.371 ± 1.261
0.0AspXaa: 0.0 ± 0.0
Glu
4.741GluAla: 4.741 ± 1.408
0.79GluCys: 0.79 ± 0.588
3.161GluAsp: 3.161 ± 1.122
6.717GluGlu: 6.717 ± 1.482
2.371GluPhe: 2.371 ± 1.113
5.531GluGly: 5.531 ± 1.702
3.951GluHis: 3.951 ± 1.08
4.741GluIle: 4.741 ± 1.875
5.927GluLys: 5.927 ± 1.628
8.297GluLeu: 8.297 ± 1.538
1.58GluMet: 1.58 ± 0.927
4.346GluAsn: 4.346 ± 1.248
4.346GluPro: 4.346 ± 1.764
1.976GluGln: 1.976 ± 0.676
4.346GluArg: 4.346 ± 1.692
3.161GluSer: 3.161 ± 1.153
5.136GluThr: 5.136 ± 0.637
3.556GluVal: 3.556 ± 1.342
0.395GluTrp: 0.395 ± 1.218
3.161GluTyr: 3.161 ± 1.161
0.0GluXaa: 0.0 ± 0.0
Phe
2.766PheAla: 2.766 ± 1.727
1.185PheCys: 1.185 ± 0.631
3.951PheAsp: 3.951 ± 0.509
2.371PheGlu: 2.371 ± 1.536
1.976PhePhe: 1.976 ± 0.673
2.371PheGly: 2.371 ± 0.865
0.395PheHis: 0.395 ± 0.607
1.976PheIle: 1.976 ± 1.147
2.766PheLys: 2.766 ± 1.048
3.161PheLeu: 3.161 ± 0.892
1.58PheMet: 1.58 ± 0.841
2.766PheAsn: 2.766 ± 0.669
1.185PhePro: 1.185 ± 0.881
1.58PheGln: 1.58 ± 0.841
3.161PheArg: 3.161 ± 1.217
2.371PheSer: 2.371 ± 0.865
0.79PheThr: 0.79 ± 0.42
1.185PheVal: 1.185 ± 0.494
0.0PheTrp: 0.0 ± 0.0
0.395PheTyr: 0.395 ± 0.21
0.0PheXaa: 0.0 ± 0.0
Gly
5.927GlyAla: 5.927 ± 2.43
0.79GlyCys: 0.79 ± 1.385
5.531GlyAsp: 5.531 ± 1.819
4.346GlyGlu: 4.346 ± 1.242
3.951GlyPhe: 3.951 ± 1.073
4.741GlyGly: 4.741 ± 1.658
1.185GlyHis: 1.185 ± 0.881
3.161GlyIle: 3.161 ± 1.222
2.766GlyLys: 2.766 ± 1.034
3.951GlyLeu: 3.951 ± 1.052
1.58GlyMet: 1.58 ± 0.588
1.976GlyAsn: 1.976 ± 1.346
3.161GlyPro: 3.161 ± 1.114
3.161GlyGln: 3.161 ± 0.707
4.346GlyArg: 4.346 ± 2.2
3.951GlySer: 3.951 ± 1.61
5.136GlyThr: 5.136 ± 1.307
3.951GlyVal: 3.951 ± 1.776
1.976GlyTrp: 1.976 ± 0.673
4.346GlyTyr: 4.346 ± 1.236
0.0GlyXaa: 0.0 ± 0.0
His
1.976HisAla: 1.976 ± 1.051
0.79HisCys: 0.79 ± 0.512
0.79HisAsp: 0.79 ± 0.512
1.185HisGlu: 1.185 ± 1.045
0.79HisPhe: 0.79 ± 0.609
0.79HisGly: 0.79 ± 1.214
0.79HisHis: 0.79 ± 0.42
0.79HisIle: 0.79 ± 0.609
2.766HisLys: 2.766 ± 1.172
4.346HisLeu: 4.346 ± 1.163
0.79HisMet: 0.79 ± 0.42
0.395HisAsn: 0.395 ± 0.721
1.185HisPro: 1.185 ± 1.104
0.79HisGln: 0.79 ± 1.037
1.976HisArg: 1.976 ± 0.688
2.371HisSer: 2.371 ± 1.261
0.79HisThr: 0.79 ± 1.115
1.185HisVal: 1.185 ± 0.494
0.0HisTrp: 0.0 ± 0.0
0.79HisTyr: 0.79 ± 0.588
0.0HisXaa: 0.0 ± 0.0
Ile
3.556IleAla: 3.556 ± 1.489
1.58IleCys: 1.58 ± 2.23
6.717IleAsp: 6.717 ± 1.848
5.927IleGlu: 5.927 ± 2.099
1.185IlePhe: 1.185 ± 1.104
1.976IleGly: 1.976 ± 0.676
1.58IleHis: 1.58 ± 0.841
4.346IleIle: 4.346 ± 1.221
3.951IleLys: 3.951 ± 1.456
2.766IleLeu: 2.766 ± 1.158
1.58IleMet: 1.58 ± 0.588
3.556IleAsn: 3.556 ± 1.722
1.976IlePro: 1.976 ± 0.984
1.976IleGln: 1.976 ± 1.007
3.556IleArg: 3.556 ± 1.749
4.741IleSer: 4.741 ± 1.891
3.556IleThr: 3.556 ± 1.315
1.58IleVal: 1.58 ± 0.561
0.395IleTrp: 0.395 ± 0.21
1.976IleTyr: 1.976 ± 0.718
0.0IleXaa: 0.0 ± 0.0
Lys
4.346LysAla: 4.346 ± 0.643
2.371LysCys: 2.371 ± 0.943
3.161LysAsp: 3.161 ± 1.471
8.692LysGlu: 8.692 ± 1.081
1.58LysPhe: 1.58 ± 0.841
8.297LysGly: 8.297 ± 1.182
2.371LysHis: 2.371 ± 1.441
4.346LysIle: 4.346 ± 1.688
3.161LysLys: 3.161 ± 1.217
5.927LysLeu: 5.927 ± 1.213
3.161LysMet: 3.161 ± 1.122
3.161LysAsn: 3.161 ± 1.216
0.79LysPro: 0.79 ± 0.512
3.556LysGln: 3.556 ± 1.091
4.346LysArg: 4.346 ± 1.811
2.766LysSer: 2.766 ± 1.036
4.346LysThr: 4.346 ± 1.074
5.531LysVal: 5.531 ± 1.358
0.395LysTrp: 0.395 ± 0.21
1.185LysTyr: 1.185 ± 1.317
0.0LysXaa: 0.0 ± 0.0
Leu
5.136LeuAla: 5.136 ± 2.034
2.371LeuCys: 2.371 ± 2.167
4.741LeuAsp: 4.741 ± 2.001
3.951LeuGlu: 3.951 ± 1.661
6.322LeuPhe: 6.322 ± 1.832
7.112LeuGly: 7.112 ± 1.089
1.976LeuHis: 1.976 ± 1.821
4.741LeuIle: 4.741 ± 0.788
11.063LeuLys: 11.063 ± 2.029
9.087LeuLeu: 9.087 ± 1.662
2.371LeuMet: 2.371 ± 1.261
4.741LeuAsn: 4.741 ± 2.127
3.556LeuPro: 3.556 ± 1.892
2.371LeuGln: 2.371 ± 1.082
7.507LeuArg: 7.507 ± 1.78
7.902LeuSer: 7.902 ± 2.704
3.161LeuThr: 3.161 ± 1.089
5.136LeuVal: 5.136 ± 1.72
0.395LeuTrp: 0.395 ± 0.21
2.766LeuTyr: 2.766 ± 1.172
0.0LeuXaa: 0.0 ± 0.0
Met
1.976MetAla: 1.976 ± 1.051
1.185MetCys: 1.185 ± 1.367
1.58MetAsp: 1.58 ± 1.108
3.161MetGlu: 3.161 ± 1.153
0.79MetPhe: 0.79 ± 0.588
3.556MetGly: 3.556 ± 1.892
0.395MetHis: 0.395 ± 0.607
1.58MetIle: 1.58 ± 0.841
1.58MetLys: 1.58 ± 1.024
1.185MetLeu: 1.185 ± 0.561
0.79MetMet: 0.79 ± 0.42
0.79MetAsn: 0.79 ± 0.512
0.79MetPro: 0.79 ± 0.512
0.395MetGln: 0.395 ± 0.21
1.58MetArg: 1.58 ± 0.841
3.556MetSer: 3.556 ± 0.936
0.79MetThr: 0.79 ± 0.512
1.58MetVal: 1.58 ± 0.561
0.0MetTrp: 0.0 ± 0.0
1.58MetTyr: 1.58 ± 0.609
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.395AsnCys: 0.395 ± 1.218
0.79AsnAsp: 0.79 ± 0.42
4.346AsnGlu: 4.346 ± 1.286
1.185AsnPhe: 1.185 ± 0.494
3.556AsnGly: 3.556 ± 1.073
1.976AsnHis: 1.976 ± 0.688
3.951AsnIle: 3.951 ± 0.962
3.161AsnLys: 3.161 ± 1.29
5.531AsnLeu: 5.531 ± 1.415
0.79AsnMet: 0.79 ± 0.42
1.185AsnAsn: 1.185 ± 1.286
1.58AsnPro: 1.58 ± 0.841
1.185AsnGln: 1.185 ± 0.556
1.185AsnArg: 1.185 ± 1.104
1.976AsnSer: 1.976 ± 0.902
1.976AsnThr: 1.976 ± 1.051
1.58AsnVal: 1.58 ± 0.588
0.0AsnTrp: 0.0 ± 0.0
1.976AsnTyr: 1.976 ± 1.051
0.0AsnXaa: 0.0 ± 0.0
Pro
1.58ProAla: 1.58 ± 0.841
0.395ProCys: 0.395 ± 0.21
3.161ProAsp: 3.161 ± 1.217
3.556ProGlu: 3.556 ± 1.669
0.79ProPhe: 0.79 ± 0.588
5.136ProGly: 5.136 ± 2.305
0.79ProHis: 0.79 ± 0.512
2.766ProIle: 2.766 ± 0.974
0.79ProLys: 0.79 ± 0.512
3.161ProLeu: 3.161 ± 2.081
0.79ProMet: 0.79 ± 0.42
1.58ProAsn: 1.58 ± 1.024
1.58ProPro: 1.58 ± 2.035
1.185ProGln: 1.185 ± 0.561
2.371ProArg: 2.371 ± 0.638
3.161ProSer: 3.161 ± 1.153
1.976ProThr: 1.976 ± 0.676
0.0ProVal: 0.0 ± 0.0
0.395ProTrp: 0.395 ± 0.21
2.371ProTyr: 2.371 ± 0.988
0.0ProXaa: 0.0 ± 0.0
Gln
1.976GlnAla: 1.976 ± 0.718
0.79GlnCys: 0.79 ± 0.42
1.185GlnAsp: 1.185 ± 0.631
1.185GlnGlu: 1.185 ± 0.494
0.0GlnPhe: 0.0 ± 0.0
1.58GlnGly: 1.58 ± 0.581
0.0GlnHis: 0.0 ± 0.0
2.371GlnIle: 2.371 ± 0.943
2.766GlnLys: 2.766 ± 1.158
4.346GlnLeu: 4.346 ± 1.221
2.766GlnMet: 2.766 ± 1.305
1.976GlnAsn: 1.976 ± 0.665
1.58GlnPro: 1.58 ± 0.561
1.58GlnGln: 1.58 ± 0.752
1.185GlnArg: 1.185 ± 1.236
3.161GlnSer: 3.161 ± 1.176
1.185GlnThr: 1.185 ± 0.556
1.58GlnVal: 1.58 ± 0.588
0.0GlnTrp: 0.0 ± 0.0
1.976GlnTyr: 1.976 ± 1.051
0.0GlnXaa: 0.0 ± 0.0
Arg
4.346ArgAla: 4.346 ± 1.472
0.79ArgCys: 0.79 ± 0.42
1.976ArgAsp: 1.976 ± 0.673
4.346ArgGlu: 4.346 ± 1.8
2.371ArgPhe: 2.371 ± 0.849
6.717ArgGly: 6.717 ± 1.108
0.395ArgHis: 0.395 ± 0.21
2.766ArgIle: 2.766 ± 1.225
4.346ArgLys: 4.346 ± 2.029
7.507ArgLeu: 7.507 ± 1.838
2.371ArgMet: 2.371 ± 0.64
2.371ArgAsn: 2.371 ± 0.849
0.79ArgPro: 0.79 ± 0.609
2.371ArgGln: 2.371 ± 1.059
5.136ArgArg: 5.136 ± 2.956
4.741ArgSer: 4.741 ± 0.872
5.136ArgThr: 5.136 ± 1.716
3.556ArgVal: 3.556 ± 2.331
0.395ArgTrp: 0.395 ± 0.21
1.976ArgTyr: 1.976 ± 1.007
0.0ArgXaa: 0.0 ± 0.0
Ser
3.161SerAla: 3.161 ± 0.464
0.395SerCys: 0.395 ± 0.607
4.346SerAsp: 4.346 ± 1.733
4.346SerGlu: 4.346 ± 0.959
4.346SerPhe: 4.346 ± 1.688
3.556SerGly: 3.556 ± 1.406
1.185SerHis: 1.185 ± 0.631
5.531SerIle: 5.531 ± 0.859
4.346SerLys: 4.346 ± 1.586
6.717SerLeu: 6.717 ± 1.746
2.766SerMet: 2.766 ± 1.027
1.58SerAsn: 1.58 ± 1.015
1.185SerPro: 1.185 ± 0.631
2.766SerGln: 2.766 ± 0.573
6.322SerArg: 6.322 ± 3.749
6.717SerSer: 6.717 ± 2.17
5.531SerThr: 5.531 ± 1.783
3.951SerVal: 3.951 ± 1.052
0.395SerTrp: 0.395 ± 0.21
1.58SerTyr: 1.58 ± 0.581
0.0SerXaa: 0.0 ± 0.0
Thr
2.371ThrAla: 2.371 ± 1.121
1.185ThrCys: 1.185 ± 0.631
3.556ThrAsp: 3.556 ± 1.022
5.927ThrGlu: 5.927 ± 2.028
3.161ThrPhe: 3.161 ± 1.29
3.161ThrGly: 3.161 ± 1.609
1.976ThrHis: 1.976 ± 0.718
3.161ThrIle: 3.161 ± 1.216
5.136ThrLys: 5.136 ± 0.899
5.927ThrLeu: 5.927 ± 2.225
1.185ThrMet: 1.185 ± 0.445
0.79ThrAsn: 0.79 ± 0.42
2.371ThrPro: 2.371 ± 1.258
0.79ThrGln: 0.79 ± 0.588
2.371ThrArg: 2.371 ± 0.811
3.556ThrSer: 3.556 ± 1.531
2.371ThrThr: 2.371 ± 1.412
2.766ThrVal: 2.766 ± 1.692
0.395ThrTrp: 0.395 ± 0.21
1.185ThrTyr: 1.185 ± 0.631
0.0ThrXaa: 0.0 ± 0.0
Val
3.161ValAla: 3.161 ± 0.991
1.185ValCys: 1.185 ± 0.494
3.556ValAsp: 3.556 ± 3.295
3.556ValGlu: 3.556 ± 1.304
1.185ValPhe: 1.185 ± 0.561
1.58ValGly: 1.58 ± 1.203
2.766ValHis: 2.766 ± 1.036
2.371ValIle: 2.371 ± 0.849
5.136ValLys: 5.136 ± 1.289
4.741ValLeu: 4.741 ± 1.278
1.58ValMet: 1.58 ± 0.588
1.185ValAsn: 1.185 ± 0.631
3.951ValPro: 3.951 ± 1.854
1.58ValGln: 1.58 ± 0.561
3.161ValArg: 3.161 ± 1.089
3.951ValSer: 3.951 ± 1.073
1.58ValThr: 1.58 ± 1.015
2.766ValVal: 2.766 ± 0.573
0.395ValTrp: 0.395 ± 0.21
2.766ValTyr: 2.766 ± 2.822
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.395TrpCys: 0.395 ± 0.21
0.0TrpAsp: 0.0 ± 0.0
0.79TrpGlu: 0.79 ± 0.609
0.0TrpPhe: 0.0 ± 0.0
0.395TrpGly: 0.395 ± 0.21
0.0TrpHis: 0.0 ± 0.0
0.395TrpIle: 0.395 ± 1.218
0.395TrpLys: 0.395 ± 0.21
0.79TrpLeu: 0.79 ± 0.42
0.0TrpMet: 0.0 ± 0.0
0.395TrpAsn: 0.395 ± 0.21
1.185TrpPro: 1.185 ± 0.631
0.0TrpGln: 0.0 ± 0.0
0.395TrpArg: 0.395 ± 0.21
0.79TrpSer: 0.79 ± 0.42
1.185TrpThr: 1.185 ± 0.631
0.395TrpVal: 0.395 ± 1.218
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.371TyrAla: 2.371 ± 1.813
0.395TyrCys: 0.395 ± 1.218
3.556TyrAsp: 3.556 ± 1.069
2.766TyrGlu: 2.766 ± 0.974
0.79TyrPhe: 0.79 ± 0.512
1.185TyrGly: 1.185 ± 0.631
1.185TyrHis: 1.185 ± 0.631
2.766TyrIle: 2.766 ± 0.571
3.556TyrLys: 3.556 ± 1.237
5.531TyrLeu: 5.531 ± 1.186
0.0TyrMet: 0.0 ± 0.0
1.58TyrAsn: 1.58 ± 0.841
1.976TyrPro: 1.976 ± 2.151
1.185TyrGln: 1.185 ± 0.494
0.79TyrArg: 0.79 ± 0.42
3.556TyrSer: 3.556 ± 0.89
1.976TyrThr: 1.976 ± 0.673
0.79TyrVal: 0.79 ± 0.42
0.79TyrTrp: 0.79 ± 1.115
1.185TyrTyr: 1.185 ± 0.631
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2532 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski