Amino acid dipepetide frequency for Achromobacter phage vB_AxyP_19-32_Axy21

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
21.062AlaAla: 21.062 ± 1.741
0.929AlaCys: 0.929 ± 0.298
6.737AlaAsp: 6.737 ± 0.836
6.892AlaGlu: 6.892 ± 0.722
3.485AlaPhe: 3.485 ± 0.536
10.067AlaGly: 10.067 ± 1.298
2.246AlaHis: 2.246 ± 0.361
4.027AlaIle: 4.027 ± 0.596
5.808AlaLys: 5.808 ± 0.746
10.918AlaLeu: 10.918 ± 0.856
4.104AlaMet: 4.104 ± 0.603
4.724AlaAsn: 4.724 ± 0.374
6.195AlaPro: 6.195 ± 2.036
7.821AlaGln: 7.821 ± 1.092
7.279AlaArg: 7.279 ± 0.843
5.963AlaSer: 5.963 ± 1.091
5.885AlaThr: 5.885 ± 0.703
8.363AlaVal: 8.363 ± 1.131
1.084AlaTrp: 1.084 ± 0.299
3.949AlaTyr: 3.949 ± 0.72
0.0AlaXaa: 0.0 ± 0.0
Cys
0.465CysAla: 0.465 ± 0.208
0.077CysCys: 0.077 ± 0.089
0.465CysAsp: 0.465 ± 0.227
0.31CysGlu: 0.31 ± 0.161
0.155CysPhe: 0.155 ± 0.104
0.619CysGly: 0.619 ± 0.237
0.155CysHis: 0.155 ± 0.106
0.465CysIle: 0.465 ± 0.191
0.155CysLys: 0.155 ± 0.1
0.697CysLeu: 0.697 ± 0.245
0.232CysMet: 0.232 ± 0.14
0.155CysAsn: 0.155 ± 0.109
0.387CysPro: 0.387 ± 0.192
0.155CysGln: 0.155 ± 0.145
0.697CysArg: 0.697 ± 0.262
0.232CysSer: 0.232 ± 0.136
0.31CysThr: 0.31 ± 0.173
0.774CysVal: 0.774 ± 0.209
0.077CysTrp: 0.077 ± 0.088
0.387CysTyr: 0.387 ± 0.172
0.0CysXaa: 0.0 ± 0.0
Asp
7.434AspAla: 7.434 ± 0.622
0.697AspCys: 0.697 ± 0.255
2.788AspAsp: 2.788 ± 0.48
2.943AspGlu: 2.943 ± 0.457
1.239AspPhe: 1.239 ± 0.227
4.878AspGly: 4.878 ± 0.608
1.316AspHis: 1.316 ± 0.361
3.33AspIle: 3.33 ± 0.458
2.091AspLys: 2.091 ± 0.378
5.498AspLeu: 5.498 ± 0.695
1.704AspMet: 1.704 ± 0.379
2.013AspAsn: 2.013 ± 0.373
3.33AspPro: 3.33 ± 0.516
2.168AspGln: 2.168 ± 0.371
3.485AspArg: 3.485 ± 0.603
4.569AspSer: 4.569 ± 0.537
2.865AspThr: 2.865 ± 0.601
4.104AspVal: 4.104 ± 0.431
0.697AspTrp: 0.697 ± 0.201
2.091AspTyr: 2.091 ± 0.469
0.0AspXaa: 0.0 ± 0.0
Glu
8.208GluAla: 8.208 ± 0.886
0.232GluCys: 0.232 ± 0.145
2.943GluAsp: 2.943 ± 0.385
2.555GluGlu: 2.555 ± 0.512
2.71GluPhe: 2.71 ± 0.495
3.562GluGly: 3.562 ± 0.421
1.471GluHis: 1.471 ± 0.497
2.633GluIle: 2.633 ± 0.644
2.168GluLys: 2.168 ± 0.425
4.491GluLeu: 4.491 ± 0.539
1.936GluMet: 1.936 ± 0.363
1.704GluAsn: 1.704 ± 0.308
1.084GluPro: 1.084 ± 0.258
2.168GluGln: 2.168 ± 0.42
4.182GluArg: 4.182 ± 0.55
2.633GluSer: 2.633 ± 0.591
2.788GluThr: 2.788 ± 0.423
3.717GluVal: 3.717 ± 0.535
1.007GluTrp: 1.007 ± 0.297
1.936GluTyr: 1.936 ± 0.36
0.0GluXaa: 0.0 ± 0.0
Phe
3.872PheAla: 3.872 ± 0.503
0.387PheCys: 0.387 ± 0.124
2.555PheAsp: 2.555 ± 0.415
1.549PheGlu: 1.549 ± 0.354
0.774PhePhe: 0.774 ± 0.268
1.936PheGly: 1.936 ± 0.379
0.542PheHis: 0.542 ± 0.21
1.084PheIle: 1.084 ± 0.266
1.162PheLys: 1.162 ± 0.259
2.091PheLeu: 2.091 ± 0.42
0.697PheMet: 0.697 ± 0.182
2.091PheAsn: 2.091 ± 0.295
2.091PhePro: 2.091 ± 0.345
0.929PheGln: 0.929 ± 0.273
1.626PheArg: 1.626 ± 0.392
1.936PheSer: 1.936 ± 0.512
2.246PheThr: 2.246 ± 0.405
2.555PheVal: 2.555 ± 0.436
0.465PheTrp: 0.465 ± 0.178
0.852PheTyr: 0.852 ± 0.239
0.0PheXaa: 0.0 ± 0.0
Gly
7.898GlyAla: 7.898 ± 0.696
0.155GlyCys: 0.155 ± 0.106
4.878GlyAsp: 4.878 ± 0.518
2.943GlyGlu: 2.943 ± 0.487
2.246GlyPhe: 2.246 ± 0.439
6.814GlyGly: 6.814 ± 1.104
1.007GlyHis: 1.007 ± 0.233
3.717GlyIle: 3.717 ± 0.512
5.111GlyLys: 5.111 ± 0.798
6.195GlyLeu: 6.195 ± 0.734
3.02GlyMet: 3.02 ± 0.588
3.097GlyAsn: 3.097 ± 0.52
2.4GlyPro: 2.4 ± 0.574
3.872GlyGln: 3.872 ± 0.49
6.427GlyArg: 6.427 ± 0.559
3.794GlySer: 3.794 ± 0.453
4.801GlyThr: 4.801 ± 0.846
6.582GlyVal: 6.582 ± 0.64
0.774GlyTrp: 0.774 ± 0.208
1.704GlyTyr: 1.704 ± 0.272
0.0GlyXaa: 0.0 ± 0.0
His
2.71HisAla: 2.71 ± 0.437
0.232HisCys: 0.232 ± 0.185
1.239HisAsp: 1.239 ± 0.43
1.007HisGlu: 1.007 ± 0.244
0.232HisPhe: 0.232 ± 0.146
1.858HisGly: 1.858 ± 0.369
0.774HisHis: 0.774 ± 0.21
1.471HisIle: 1.471 ± 0.313
0.852HisLys: 0.852 ± 0.274
1.626HisLeu: 1.626 ± 0.354
0.619HisMet: 0.619 ± 0.197
0.619HisAsn: 0.619 ± 0.282
0.697HisPro: 0.697 ± 0.241
0.929HisGln: 0.929 ± 0.293
0.929HisArg: 0.929 ± 0.253
1.007HisSer: 1.007 ± 0.278
1.316HisThr: 1.316 ± 0.335
1.549HisVal: 1.549 ± 0.353
0.619HisTrp: 0.619 ± 0.261
0.619HisTyr: 0.619 ± 0.269
0.0HisXaa: 0.0 ± 0.0
Ile
4.491IleAla: 4.491 ± 0.713
0.232IleCys: 0.232 ± 0.128
3.717IleAsp: 3.717 ± 0.563
1.936IleGlu: 1.936 ± 0.436
0.465IlePhe: 0.465 ± 0.188
3.175IleGly: 3.175 ± 0.535
1.007IleHis: 1.007 ± 0.306
1.858IleIle: 1.858 ± 0.305
2.71IleLys: 2.71 ± 0.413
3.097IleLeu: 3.097 ± 0.577
0.852IleMet: 0.852 ± 0.284
2.013IleAsn: 2.013 ± 0.403
1.781IlePro: 1.781 ± 0.349
2.013IleGln: 2.013 ± 0.448
2.788IleArg: 2.788 ± 0.483
1.858IleSer: 1.858 ± 0.347
2.71IleThr: 2.71 ± 0.452
3.175IleVal: 3.175 ± 0.503
0.465IleTrp: 0.465 ± 0.206
1.007IleTyr: 1.007 ± 0.19
0.0IleXaa: 0.0 ± 0.0
Lys
6.737LysAla: 6.737 ± 0.784
0.155LysCys: 0.155 ± 0.098
2.555LysAsp: 2.555 ± 0.453
2.555LysGlu: 2.555 ± 0.508
1.626LysPhe: 1.626 ± 0.339
2.943LysGly: 2.943 ± 0.489
0.852LysHis: 0.852 ± 0.374
1.626LysIle: 1.626 ± 0.348
1.858LysLys: 1.858 ± 0.456
4.724LysLeu: 4.724 ± 0.531
0.697LysMet: 0.697 ± 0.256
1.162LysAsn: 1.162 ± 0.266
1.781LysPro: 1.781 ± 0.35
1.936LysGln: 1.936 ± 0.359
3.175LysArg: 3.175 ± 0.553
2.246LysSer: 2.246 ± 0.333
1.549LysThr: 1.549 ± 0.447
3.33LysVal: 3.33 ± 0.428
0.852LysTrp: 0.852 ± 0.247
2.013LysTyr: 2.013 ± 0.317
0.0LysXaa: 0.0 ± 0.0
Leu
11.77LeuAla: 11.77 ± 1.243
0.619LeuCys: 0.619 ± 0.236
5.885LeuAsp: 5.885 ± 0.62
4.878LeuGlu: 4.878 ± 0.581
2.4LeuPhe: 2.4 ± 0.399
5.498LeuGly: 5.498 ± 0.65
2.013LeuHis: 2.013 ± 0.387
4.182LeuIle: 4.182 ± 0.647
3.33LeuLys: 3.33 ± 0.681
6.969LeuLeu: 6.969 ± 0.977
2.013LeuMet: 2.013 ± 0.398
3.252LeuAsn: 3.252 ± 0.352
3.485LeuPro: 3.485 ± 0.512
3.872LeuGln: 3.872 ± 0.539
6.117LeuArg: 6.117 ± 0.799
5.42LeuSer: 5.42 ± 0.643
5.42LeuThr: 5.42 ± 0.663
4.414LeuVal: 4.414 ± 0.516
1.162LeuTrp: 1.162 ± 0.235
2.323LeuTyr: 2.323 ± 0.446
0.0LeuXaa: 0.0 ± 0.0
Met
3.33MetAla: 3.33 ± 0.659
0.077MetCys: 0.077 ± 0.074
1.239MetAsp: 1.239 ± 0.331
1.239MetGlu: 1.239 ± 0.361
0.929MetPhe: 0.929 ± 0.243
1.781MetGly: 1.781 ± 0.443
0.929MetHis: 0.929 ± 0.291
1.007MetIle: 1.007 ± 0.275
1.316MetLys: 1.316 ± 0.439
2.4MetLeu: 2.4 ± 0.464
0.774MetMet: 0.774 ± 0.216
0.929MetAsn: 0.929 ± 0.297
1.239MetPro: 1.239 ± 0.32
2.246MetGln: 2.246 ± 0.594
2.168MetArg: 2.168 ± 0.444
1.781MetSer: 1.781 ± 0.398
1.394MetThr: 1.394 ± 0.388
1.858MetVal: 1.858 ± 0.316
0.465MetTrp: 0.465 ± 0.15
1.162MetTyr: 1.162 ± 0.241
0.0MetXaa: 0.0 ± 0.0
Asn
3.407AsnAla: 3.407 ± 0.6
0.077AsnCys: 0.077 ± 0.073
1.936AsnAsp: 1.936 ± 0.278
2.633AsnGlu: 2.633 ± 0.421
1.162AsnPhe: 1.162 ± 0.256
2.71AsnGly: 2.71 ± 0.49
0.774AsnHis: 0.774 ± 0.262
1.626AsnIle: 1.626 ± 0.387
1.704AsnLys: 1.704 ± 0.404
2.865AsnLeu: 2.865 ± 0.34
1.162AsnMet: 1.162 ± 0.378
1.162AsnAsn: 1.162 ± 0.302
2.168AsnPro: 2.168 ± 0.455
1.704AsnGln: 1.704 ± 0.331
2.478AsnArg: 2.478 ± 0.435
1.549AsnSer: 1.549 ± 0.239
2.091AsnThr: 2.091 ± 0.274
2.555AsnVal: 2.555 ± 0.547
0.774AsnTrp: 0.774 ± 0.248
1.162AsnTyr: 1.162 ± 0.263
0.0AsnXaa: 0.0 ± 0.0
Pro
6.505ProAla: 6.505 ± 1.462
0.31ProCys: 0.31 ± 0.14
3.717ProAsp: 3.717 ± 0.46
3.175ProGlu: 3.175 ± 0.637
1.626ProPhe: 1.626 ± 0.259
4.259ProGly: 4.259 ± 0.634
0.619ProHis: 0.619 ± 0.199
1.239ProIle: 1.239 ± 0.29
1.471ProLys: 1.471 ± 0.29
3.097ProLeu: 3.097 ± 0.571
1.084ProMet: 1.084 ± 0.251
1.084ProAsn: 1.084 ± 0.253
2.478ProPro: 2.478 ± 0.706
2.013ProGln: 2.013 ± 0.406
2.091ProArg: 2.091 ± 0.427
2.4ProSer: 2.4 ± 0.281
2.555ProThr: 2.555 ± 0.401
4.336ProVal: 4.336 ± 1.032
0.232ProTrp: 0.232 ± 0.131
1.239ProTyr: 1.239 ± 0.312
0.0ProXaa: 0.0 ± 0.0
Gln
6.582GlnAla: 6.582 ± 0.591
0.542GlnCys: 0.542 ± 0.211
2.091GlnAsp: 2.091 ± 0.29
2.71GlnGlu: 2.71 ± 0.868
1.394GlnPhe: 1.394 ± 0.268
3.949GlnGly: 3.949 ± 0.468
0.929GlnHis: 0.929 ± 0.252
1.781GlnIle: 1.781 ± 0.291
2.091GlnLys: 2.091 ± 0.397
4.956GlnLeu: 4.956 ± 0.657
1.858GlnMet: 1.858 ± 0.341
1.394GlnAsn: 1.394 ± 0.406
2.4GlnPro: 2.4 ± 0.727
3.33GlnGln: 3.33 ± 0.772
4.259GlnArg: 4.259 ± 0.555
2.943GlnSer: 2.943 ± 0.485
2.323GlnThr: 2.323 ± 0.545
2.478GlnVal: 2.478 ± 0.415
0.774GlnTrp: 0.774 ± 0.18
1.316GlnTyr: 1.316 ± 0.408
0.0GlnXaa: 0.0 ± 0.0
Arg
7.898ArgAla: 7.898 ± 0.987
0.697ArgCys: 0.697 ± 0.281
4.336ArgAsp: 4.336 ± 0.55
3.949ArgGlu: 3.949 ± 0.606
1.549ArgPhe: 1.549 ± 0.324
4.027ArgGly: 4.027 ± 0.591
1.007ArgHis: 1.007 ± 0.311
3.639ArgIle: 3.639 ± 0.528
3.33ArgLys: 3.33 ± 0.492
5.42ArgLeu: 5.42 ± 0.63
2.246ArgMet: 2.246 ± 0.34
2.633ArgAsn: 2.633 ± 0.383
3.02ArgPro: 3.02 ± 0.407
3.02ArgGln: 3.02 ± 0.592
4.569ArgArg: 4.569 ± 0.639
2.943ArgSer: 2.943 ± 0.504
3.717ArgThr: 3.717 ± 0.63
4.724ArgVal: 4.724 ± 0.681
1.549ArgTrp: 1.549 ± 0.331
1.936ArgTyr: 1.936 ± 0.406
0.0ArgXaa: 0.0 ± 0.0
Ser
6.505SerAla: 6.505 ± 0.807
0.232SerCys: 0.232 ± 0.222
3.175SerAsp: 3.175 ± 0.416
2.478SerGlu: 2.478 ± 0.418
2.168SerPhe: 2.168 ± 0.318
5.42SerGly: 5.42 ± 0.596
1.007SerHis: 1.007 ± 0.312
1.007SerIle: 1.007 ± 0.28
2.478SerLys: 2.478 ± 0.473
4.569SerLeu: 4.569 ± 0.619
0.774SerMet: 0.774 ± 0.25
2.788SerAsn: 2.788 ± 0.517
2.555SerPro: 2.555 ± 0.403
3.02SerGln: 3.02 ± 0.42
3.33SerArg: 3.33 ± 0.412
3.407SerSer: 3.407 ± 0.701
3.407SerThr: 3.407 ± 0.627
4.259SerVal: 4.259 ± 0.75
1.007SerTrp: 1.007 ± 0.325
1.471SerTyr: 1.471 ± 0.31
0.0SerXaa: 0.0 ± 0.0
Thr
5.885ThrAla: 5.885 ± 0.769
0.31ThrCys: 0.31 ± 0.134
3.485ThrAsp: 3.485 ± 0.56
3.794ThrGlu: 3.794 ± 0.597
1.781ThrPhe: 1.781 ± 0.267
5.42ThrGly: 5.42 ± 0.686
0.697ThrHis: 0.697 ± 0.269
2.865ThrIle: 2.865 ± 0.702
2.013ThrLys: 2.013 ± 0.507
5.188ThrLeu: 5.188 ± 0.703
1.316ThrMet: 1.316 ± 0.315
1.626ThrAsn: 1.626 ± 0.351
3.252ThrPro: 3.252 ± 0.442
2.71ThrGln: 2.71 ± 0.444
2.478ThrArg: 2.478 ± 0.359
3.485ThrSer: 3.485 ± 0.527
3.33ThrThr: 3.33 ± 0.567
5.188ThrVal: 5.188 ± 1.135
0.619ThrTrp: 0.619 ± 0.201
1.394ThrTyr: 1.394 ± 0.406
0.0ThrXaa: 0.0 ± 0.0
Val
8.75ValAla: 8.75 ± 1.197
0.542ValCys: 0.542 ± 0.224
3.097ValAsp: 3.097 ± 0.375
3.717ValGlu: 3.717 ± 0.553
3.097ValPhe: 3.097 ± 0.4
5.111ValGly: 5.111 ± 0.658
2.246ValHis: 2.246 ± 0.575
2.633ValIle: 2.633 ± 0.571
2.865ValLys: 2.865 ± 0.483
5.343ValLeu: 5.343 ± 0.7
2.246ValMet: 2.246 ± 0.406
1.936ValAsn: 1.936 ± 0.325
3.949ValPro: 3.949 ± 0.69
3.794ValGln: 3.794 ± 0.487
4.878ValArg: 4.878 ± 0.677
4.027ValSer: 4.027 ± 0.741
4.646ValThr: 4.646 ± 0.98
5.033ValVal: 5.033 ± 0.541
0.697ValTrp: 0.697 ± 0.18
1.858ValTyr: 1.858 ± 0.35
0.0ValXaa: 0.0 ± 0.0
Trp
1.162TrpAla: 1.162 ± 0.33
0.232TrpCys: 0.232 ± 0.131
0.697TrpAsp: 0.697 ± 0.202
0.697TrpGlu: 0.697 ± 0.169
0.542TrpPhe: 0.542 ± 0.181
1.239TrpGly: 1.239 ± 0.335
0.387TrpHis: 0.387 ± 0.165
0.31TrpIle: 0.31 ± 0.133
0.465TrpLys: 0.465 ± 0.183
1.936TrpLeu: 1.936 ± 0.473
0.232TrpMet: 0.232 ± 0.177
0.542TrpAsn: 0.542 ± 0.202
0.31TrpPro: 0.31 ± 0.14
0.852TrpGln: 0.852 ± 0.223
0.852TrpArg: 0.852 ± 0.274
1.007TrpSer: 1.007 ± 0.239
1.394TrpThr: 1.394 ± 0.318
0.465TrpVal: 0.465 ± 0.251
0.31TrpTrp: 0.31 ± 0.131
0.387TrpTyr: 0.387 ± 0.155
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.865TyrAla: 2.865 ± 0.486
0.232TyrCys: 0.232 ± 0.148
1.704TyrAsp: 1.704 ± 0.437
2.168TyrGlu: 2.168 ± 0.45
1.858TyrPhe: 1.858 ± 0.412
2.168TyrGly: 2.168 ± 0.577
0.929TyrHis: 0.929 ± 0.317
0.852TyrIle: 0.852 ± 0.26
1.394TyrLys: 1.394 ± 0.351
2.943TyrLeu: 2.943 ± 0.472
0.619TyrMet: 0.619 ± 0.223
0.774TyrAsn: 0.774 ± 0.3
0.929TyrPro: 0.929 ± 0.26
1.549TyrGln: 1.549 ± 0.229
2.4TyrArg: 2.4 ± 0.437
1.936TyrSer: 1.936 ± 0.373
2.091TyrThr: 2.091 ± 0.425
1.007TyrVal: 1.007 ± 0.387
0.387TyrTrp: 0.387 ± 0.196
0.619TyrTyr: 0.619 ± 0.21
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 49 proteins (12915 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski