Amino acid dipepetide frequency for Enterovibrio pacificus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.635AlaAla: 7.635 ± 0.098	0.98AlaCys: 0.98 ± 0.027	4.836AlaAsp: 4.836 ± 0.072	5.516AlaGlu: 5.516 ± 0.072	3.527AlaPhe: 3.527 ± 0.052	6.077AlaGly: 6.077 ± 0.09	1.545AlaHis: 1.545 ± 0.034	5.481AlaIle: 5.481 ± 0.07	4.396AlaLys: 4.396 ± 0.065	9.305AlaLeu: 9.305 ± 0.114	2.687AlaMet: 2.687 ± 0.05	3.258AlaAsn: 3.258 ± 0.056	2.708AlaPro: 2.708 ± 0.052	3.026AlaGln: 3.026 ± 0.051	3.836AlaArg: 3.836 ± 0.058	5.571AlaSer: 5.571 ± 0.079	4.28AlaThr: 4.28 ± 0.063	6.137AlaVal: 6.137 ± 0.08	0.907AlaTrp: 0.907 ± 0.028	2.209AlaTyr: 2.209 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.778CysAla: 0.778 ± 0.023	0.171CysCys: 0.171 ± 0.012	0.663CysAsp: 0.663 ± 0.024	0.657CysGlu: 0.657 ± 0.023	0.528CysPhe: 0.528 ± 0.021	0.945CysGly: 0.945 ± 0.029	0.399CysHis: 0.399 ± 0.017	0.597CysIle: 0.597 ± 0.021	0.472CysLys: 0.472 ± 0.019	1.058CysLeu: 1.058 ± 0.026	0.224CysMet: 0.224 ± 0.012	0.4CysAsn: 0.4 ± 0.017	0.464CysPro: 0.464 ± 0.018	0.52CysGln: 0.52 ± 0.021	0.59CysArg: 0.59 ± 0.024	0.765CysSer: 0.765 ± 0.023	0.461CysThr: 0.461 ± 0.018	0.671CysVal: 0.671 ± 0.022	0.166CysTrp: 0.166 ± 0.013	0.322CysTyr: 0.322 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.727AspAla: 4.727 ± 0.069	0.611AspCys: 0.611 ± 0.024	3.484AspAsp: 3.484 ± 0.069	3.892AspGlu: 3.892 ± 0.065	2.581AspPhe: 2.581 ± 0.05	4.261AspGly: 4.261 ± 0.084	1.255AspHis: 1.255 ± 0.031	4.54AspIle: 4.54 ± 0.058	3.419AspLys: 3.419 ± 0.059	5.12AspLeu: 5.12 ± 0.067	1.51AspMet: 1.51 ± 0.036	2.701AspAsn: 2.701 ± 0.056	2.219AspPro: 2.219 ± 0.041	1.993AspGln: 1.993 ± 0.043	2.57AspArg: 2.57 ± 0.045	3.596AspSer: 3.596 ± 0.062	3.138AspThr: 3.138 ± 0.066	4.124AspVal: 4.124 ± 0.067	0.874AspTrp: 0.874 ± 0.022	1.936AspTyr: 1.936 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	5.101GluAla: 5.101 ± 0.073	0.536GluCys: 0.536 ± 0.02	2.957GluAsp: 2.957 ± 0.056	3.761GluGlu: 3.761 ± 0.069	2.33GluPhe: 2.33 ± 0.044	3.71GluGly: 3.71 ± 0.067	1.583GluHis: 1.583 ± 0.036	3.821GluIle: 3.821 ± 0.053	4.229GluLys: 4.229 ± 0.065	6.653GluLeu: 6.653 ± 0.086	1.754GluMet: 1.754 ± 0.036	2.864GluAsn: 2.864 ± 0.045	2.155GluPro: 2.155 ± 0.04	3.541GluGln: 3.541 ± 0.051	3.435GluArg: 3.435 ± 0.058	3.952GluSer: 3.952 ± 0.062	3.228GluThr: 3.228 ± 0.054	4.176GluVal: 4.176 ± 0.059	0.802GluTrp: 0.802 ± 0.026	1.728GluTyr: 1.728 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.46PheAla: 3.46 ± 0.061	0.534PheCys: 0.534 ± 0.017	2.96PheAsp: 2.96 ± 0.047	2.521PheGlu: 2.521 ± 0.048	1.908PhePhe: 1.908 ± 0.048	3.325PheGly: 3.325 ± 0.053	0.91PheHis: 0.91 ± 0.023	2.742PheIle: 2.742 ± 0.047	1.802PheLys: 1.802 ± 0.038	3.573PheLeu: 3.573 ± 0.064	0.971PheMet: 0.971 ± 0.03	2.01PheAsn: 2.01 ± 0.033	1.491PhePro: 1.491 ± 0.038	1.217PheGln: 1.217 ± 0.029	1.832PheArg: 1.832 ± 0.042	3.869PheSer: 3.869 ± 0.065	2.437PheThr: 2.437 ± 0.043	2.837PheVal: 2.837 ± 0.046	0.619PheTrp: 0.619 ± 0.022	1.386PheTyr: 1.386 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.149GlyAla: 5.149 ± 0.076	0.937GlyCys: 0.937 ± 0.027	4.043GlyAsp: 4.043 ± 0.061	4.507GlyGlu: 4.507 ± 0.061	3.492GlyPhe: 3.492 ± 0.058	4.962GlyGly: 4.962 ± 0.078	1.595GlyHis: 1.595 ± 0.037	4.662GlyIle: 4.662 ± 0.073	4.259GlyLys: 4.259 ± 0.06	6.887GlyLeu: 6.887 ± 0.09	2.006GlyMet: 2.006 ± 0.041	2.813GlyAsn: 2.813 ± 0.06	1.755GlyPro: 1.755 ± 0.041	2.901GlyGln: 2.901 ± 0.05	3.301GlyArg: 3.301 ± 0.047	4.165GlySer: 4.165 ± 0.07	3.524GlyThr: 3.524 ± 0.056	5.105GlyVal: 5.105 ± 0.067	1.043GlyTrp: 1.043 ± 0.033	2.453GlyTyr: 2.453 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	1.608HisAla: 1.608 ± 0.033	0.384HisCys: 0.384 ± 0.018	1.139HisAsp: 1.139 ± 0.035	1.092HisGlu: 1.092 ± 0.03	1.174HisPhe: 1.174 ± 0.029	1.644HisGly: 1.644 ± 0.037	0.741HisHis: 0.741 ± 0.029	1.49HisIle: 1.49 ± 0.034	1.037HisLys: 1.037 ± 0.026	2.258HisLeu: 2.258 ± 0.038	0.507HisMet: 0.507 ± 0.019	0.869HisAsn: 0.869 ± 0.026	1.182HisPro: 1.182 ± 0.031	1.211HisGln: 1.211 ± 0.032	1.164HisArg: 1.164 ± 0.03	1.459HisSer: 1.459 ± 0.032	1.158HisThr: 1.158 ± 0.031	1.269HisVal: 1.269 ± 0.032	0.365HisTrp: 0.365 ± 0.017	0.868HisTyr: 0.868 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.858IleAla: 5.858 ± 0.069	0.722IleCys: 0.722 ± 0.023	4.474IleAsp: 4.474 ± 0.068	4.412IleGlu: 4.412 ± 0.054	2.379IlePhe: 2.379 ± 0.049	4.463IleGly: 4.463 ± 0.058	1.315IleHis: 1.315 ± 0.031	3.422IleIle: 3.422 ± 0.058	3.148IleLys: 3.148 ± 0.054	5.029IleLeu: 5.029 ± 0.07	1.224IleMet: 1.224 ± 0.034	2.97IleAsn: 2.97 ± 0.054	2.66IlePro: 2.66 ± 0.046	2.005IleGln: 2.005 ± 0.042	3.068IleArg: 3.068 ± 0.057	4.77IleSer: 4.77 ± 0.065	3.475IleThr: 3.475 ± 0.053	3.928IleVal: 3.928 ± 0.05	0.693IleTrp: 0.693 ± 0.025	1.695IleTyr: 1.695 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.694LysAla: 4.694 ± 0.069	0.378LysCys: 0.378 ± 0.018	2.823LysAsp: 2.823 ± 0.048	3.261LysGlu: 3.261 ± 0.054	1.531LysPhe: 1.531 ± 0.035	3.478LysGly: 3.478 ± 0.05	1.205LysHis: 1.205 ± 0.034	2.963LysIle: 2.963 ± 0.047	3.259LysLys: 3.259 ± 0.068	4.96LysLeu: 4.96 ± 0.066	1.394LysMet: 1.394 ± 0.032	2.352LysAsn: 2.352 ± 0.046	2.453LysPro: 2.453 ± 0.052	2.403LysGln: 2.403 ± 0.043	2.92LysArg: 2.92 ± 0.046	3.325LysSer: 3.325 ± 0.052	2.989LysThr: 2.989 ± 0.052	3.855LysVal: 3.855 ± 0.051	0.57LysTrp: 0.57 ± 0.022	1.459LysTyr: 1.459 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	9.255LeuAla: 9.255 ± 0.12	1.129LeuCys: 1.129 ± 0.03	5.8LeuAsp: 5.8 ± 0.064	5.837LeuGlu: 5.837 ± 0.07	4.24LeuPhe: 4.24 ± 0.068	6.66LeuGly: 6.66 ± 0.08	1.991LeuHis: 1.991 ± 0.036	6.007LeuIle: 6.007 ± 0.078	5.127LeuLys: 5.127 ± 0.061	10.224LeuLeu: 10.224 ± 0.116	2.731LeuMet: 2.731 ± 0.05	4.503LeuAsn: 4.503 ± 0.066	4.847LeuPro: 4.847 ± 0.067	3.138LeuGln: 3.138 ± 0.056	4.678LeuArg: 4.678 ± 0.065	8.589LeuSer: 8.589 ± 0.087	6.203LeuThr: 6.203 ± 0.068	6.873LeuVal: 6.873 ± 0.077	1.038LeuTrp: 1.038 ± 0.032	2.543LeuTyr: 2.543 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	2.617MetAla: 2.617 ± 0.051	0.223MetCys: 0.223 ± 0.012	1.281MetAsp: 1.281 ± 0.03	1.316MetGlu: 1.316 ± 0.033	0.996MetPhe: 0.996 ± 0.026	1.757MetGly: 1.757 ± 0.041	0.472MetHis: 0.472 ± 0.022	1.454MetIle: 1.454 ± 0.036	1.567MetLys: 1.567 ± 0.03	2.755MetLeu: 2.755 ± 0.054	0.8MetMet: 0.8 ± 0.025	1.089MetAsn: 1.089 ± 0.033	1.25MetPro: 1.25 ± 0.032	0.975MetGln: 0.975 ± 0.024	1.195MetArg: 1.195 ± 0.035	2.005MetSer: 2.005 ± 0.038	1.846MetThr: 1.846 ± 0.037	1.849MetVal: 1.849 ± 0.036	0.211MetTrp: 0.211 ± 0.013	0.528MetTyr: 0.528 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.382AsnAla: 3.382 ± 0.052	0.41AsnCys: 0.41 ± 0.021	2.493AsnAsp: 2.493 ± 0.047	2.429AsnGlu: 2.429 ± 0.047	1.509AsnPhe: 1.509 ± 0.034	3.001AsnGly: 3.001 ± 0.061	0.999AsnHis: 0.999 ± 0.028	2.86AsnIle: 2.86 ± 0.05	2.302AsnLys: 2.302 ± 0.04	3.766AsnLeu: 3.766 ± 0.053	0.996AsnMet: 0.996 ± 0.028	1.888AsnAsn: 1.888 ± 0.047	2.148AsnPro: 2.148 ± 0.043	1.887AsnGln: 1.887 ± 0.04	2.134AsnArg: 2.134 ± 0.04	2.459AsnSer: 2.459 ± 0.048	2.412AsnThr: 2.412 ± 0.045	2.752AsnVal: 2.752 ± 0.051	0.625AsnTrp: 0.625 ± 0.024	1.293AsnTyr: 1.293 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	3.247ProAla: 3.247 ± 0.061	0.356ProCys: 0.356 ± 0.017	2.947ProAsp: 2.947 ± 0.047	3.39ProGlu: 3.39 ± 0.05	1.785ProPhe: 1.785 ± 0.038	2.577ProGly: 2.577 ± 0.045	0.857ProHis: 0.857 ± 0.023	2.257ProIle: 2.257 ± 0.04	1.801ProLys: 1.801 ± 0.038	4.113ProLeu: 4.113 ± 0.058	1.025ProMet: 1.025 ± 0.028	1.521ProAsn: 1.521 ± 0.039	1.273ProPro: 1.273 ± 0.033	1.459ProGln: 1.459 ± 0.033	1.462ProArg: 1.462 ± 0.041	2.843ProSer: 2.843 ± 0.044	2.134ProThr: 2.134 ± 0.04	3.367ProVal: 3.367 ± 0.049	0.542ProTrp: 0.542 ± 0.022	1.243ProTyr: 1.243 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.562GlnAla: 3.562 ± 0.061	0.409GlnCys: 0.409 ± 0.017	1.92GlnAsp: 1.92 ± 0.035	2.064GlnGlu: 2.064 ± 0.043	1.615GlnPhe: 1.615 ± 0.035	2.7GlnGly: 2.7 ± 0.047	1.121GlnHis: 1.121 ± 0.03	2.301GlnIle: 2.301 ± 0.049	2.045GlnLys: 2.045 ± 0.04	4.485GlnLeu: 4.485 ± 0.06	1.04GlnMet: 1.04 ± 0.024	1.521GlnAsn: 1.521 ± 0.038	1.718GlnPro: 1.718 ± 0.039	2.647GlnGln: 2.647 ± 0.051	2.368GlnArg: 2.368 ± 0.043	2.786GlnSer: 2.786 ± 0.049	2.226GlnThr: 2.226 ± 0.038	2.739GlnVal: 2.739 ± 0.045	0.624GlnTrp: 0.624 ± 0.023	1.257GlnTyr: 1.257 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	3.574ArgAla: 3.574 ± 0.055	0.526ArgCys: 0.526 ± 0.023	2.779ArgAsp: 2.779 ± 0.044	3.423ArgGlu: 3.423 ± 0.056	2.465ArgPhe: 2.465 ± 0.045	2.835ArgGly: 2.835 ± 0.054	1.289ArgHis: 1.289 ± 0.031	2.953ArgIle: 2.953 ± 0.05	2.607ArgLys: 2.607 ± 0.049	5.347ArgLeu: 5.347 ± 0.066	1.263ArgMet: 1.263 ± 0.027	1.932ArgAsn: 1.932 ± 0.038	1.744ArgPro: 1.744 ± 0.038	2.472ArgGln: 2.472 ± 0.045	2.688ArgArg: 2.688 ± 0.052	2.737ArgSer: 2.737 ± 0.044	2.147ArgThr: 2.147 ± 0.041	3.45ArgVal: 3.45 ± 0.056	0.679ArgTrp: 0.679 ± 0.02	1.759ArgTyr: 1.759 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.673SerAla: 5.673 ± 0.085	0.636SerCys: 0.636 ± 0.023	4.309SerAsp: 4.309 ± 0.066	4.373SerGlu: 4.373 ± 0.06	3.046SerPhe: 3.046 ± 0.05	5.514SerGly: 5.514 ± 0.079	1.73SerHis: 1.73 ± 0.036	4.016SerIle: 4.016 ± 0.049	3.134SerLys: 3.134 ± 0.045	7.648SerLeu: 7.648 ± 0.082	1.807SerMet: 1.807 ± 0.035	2.529SerAsn: 2.529 ± 0.049	2.835SerPro: 2.835 ± 0.044	2.966SerGln: 2.966 ± 0.049	3.277SerArg: 3.277 ± 0.048	4.734SerSer: 4.734 ± 0.071	3.339SerThr: 3.339 ± 0.045	5.173SerVal: 5.173 ± 0.071	0.949SerTrp: 0.949 ± 0.029	2.042SerTyr: 2.042 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	4.567ThrAla: 4.567 ± 0.063	0.505ThrCys: 0.505 ± 0.022	3.231ThrAsp: 3.231 ± 0.05	3.376ThrGlu: 3.376 ± 0.06	2.262ThrPhe: 2.262 ± 0.037	4.189ThrGly: 4.189 ± 0.066	1.211ThrHis: 1.211 ± 0.034	3.196ThrIle: 3.196 ± 0.059	2.201ThrLys: 2.201 ± 0.042	6.578ThrLeu: 6.578 ± 0.091	1.212ThrMet: 1.212 ± 0.031	1.923ThrAsn: 1.923 ± 0.044	2.613ThrPro: 2.613 ± 0.046	2.04ThrGln: 2.04 ± 0.04	2.401ThrArg: 2.401 ± 0.037	3.583ThrSer: 3.583 ± 0.064	2.864ThrThr: 2.864 ± 0.058	4.196ThrVal: 4.196 ± 0.069	0.558ThrTrp: 0.558 ± 0.022	1.489ThrTyr: 1.489 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	6.175ValAla: 6.175 ± 0.09	0.835ValCys: 0.835 ± 0.03	4.199ValAsp: 4.199 ± 0.052	4.435ValGlu: 4.435 ± 0.055	2.972ValPhe: 2.972 ± 0.046	4.584ValGly: 4.584 ± 0.073	1.248ValHis: 1.248 ± 0.033	4.665ValIle: 4.665 ± 0.058	3.629ValLys: 3.629 ± 0.056	6.569ValLeu: 6.569 ± 0.075	2.069ValMet: 2.069 ± 0.045	3.08ValAsn: 3.08 ± 0.048	2.734ValPro: 2.734 ± 0.046	1.964ValGln: 1.964 ± 0.041	3.166ValArg: 3.166 ± 0.048	5.687ValSer: 5.687 ± 0.076	4.408ValThr: 4.408 ± 0.071	5.374ValVal: 5.374 ± 0.069	0.839ValTrp: 0.839 ± 0.026	1.842ValTyr: 1.842 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.784TrpAla: 0.784 ± 0.021	0.151TrpCys: 0.151 ± 0.01	0.584TrpAsp: 0.584 ± 0.021	0.574TrpGlu: 0.574 ± 0.019	0.626TrpPhe: 0.626 ± 0.023	0.824TrpGly: 0.824 ± 0.03	0.372TrpHis: 0.372 ± 0.019	0.704TrpIle: 0.704 ± 0.022	0.529TrpLys: 0.529 ± 0.02	1.814TrpLeu: 1.814 ± 0.043	0.356TrpMet: 0.356 ± 0.015	0.501TrpAsn: 0.501 ± 0.02	0.505TrpPro: 0.505 ± 0.019	0.989TrpGln: 0.989 ± 0.033	0.717TrpArg: 0.717 ± 0.024	0.794TrpSer: 0.794 ± 0.024	0.534TrpThr: 0.534 ± 0.019	0.831TrpVal: 0.831 ± 0.022	0.208TrpTrp: 0.208 ± 0.014	0.367TrpTyr: 0.367 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.07TyrAla: 2.07 ± 0.044	0.419TyrCys: 0.419 ± 0.017	1.626TyrAsp: 1.626 ± 0.04	1.484TyrGlu: 1.484 ± 0.034	1.439TyrPhe: 1.439 ± 0.032	2.056TyrGly: 2.056 ± 0.044	0.781TyrHis: 0.781 ± 0.024	1.58TyrIle: 1.58 ± 0.038	1.308TyrLys: 1.308 ± 0.035	3.271TyrLeu: 3.271 ± 0.057	0.61TyrMet: 0.61 ± 0.021	1.021TyrAsn: 1.021 ± 0.029	1.445TyrPro: 1.445 ± 0.034	1.794TyrGln: 1.794 ± 0.038	1.867TyrArg: 1.867 ± 0.038	2.04TyrSer: 2.04 ± 0.047	1.392TyrThr: 1.392 ± 0.036	1.765TyrVal: 1.765 ± 0.041	0.451TyrTrp: 0.451 ± 0.019	0.857TyrTyr: 0.857 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4376 proteins (1371859 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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