Amino acid dipepetide frequency for Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.093AlaAla: 22.093 ± 0.182	1.187AlaCys: 1.187 ± 0.029	8.69AlaAsp: 8.69 ± 0.082	7.904AlaGlu: 7.904 ± 0.106	3.423AlaPhe: 3.423 ± 0.057	14.744AlaGly: 14.744 ± 0.144	2.729AlaHis: 2.729 ± 0.044	3.944AlaIle: 3.944 ± 0.063	1.9AlaLys: 1.9 ± 0.05	13.281AlaLeu: 13.281 ± 0.112	2.393AlaMet: 2.393 ± 0.039	1.876AlaAsn: 1.876 ± 0.039	7.106AlaPro: 7.106 ± 0.088	3.335AlaGln: 3.335 ± 0.049	11.748AlaArg: 11.748 ± 0.109	6.524AlaSer: 6.524 ± 0.069	7.584AlaThr: 7.584 ± 0.082	12.311AlaVal: 12.311 ± 0.114	1.767AlaTrp: 1.767 ± 0.038	2.273AlaTyr: 2.273 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	1.089CysAla: 1.089 ± 0.029	0.121CysCys: 0.121 ± 0.011	0.502CysAsp: 0.502 ± 0.02	0.393CysGlu: 0.393 ± 0.017	0.221CysPhe: 0.221 ± 0.012	0.975CysGly: 0.975 ± 0.029	0.227CysHis: 0.227 ± 0.012	0.188CysIle: 0.188 ± 0.011	0.083CysLys: 0.083 ± 0.006	0.785CysLeu: 0.785 ± 0.025	0.113CysMet: 0.113 ± 0.009	0.122CysAsn: 0.122 ± 0.009	0.645CysPro: 0.645 ± 0.025	0.23CysGln: 0.23 ± 0.013	0.768CysArg: 0.768 ± 0.024	0.467CysSer: 0.467 ± 0.019	0.468CysThr: 0.468 ± 0.02	0.6CysVal: 0.6 ± 0.021	0.168CysTrp: 0.168 ± 0.012	0.181CysTyr: 0.181 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.66AspAla: 7.66 ± 0.08	0.422AspCys: 0.422 ± 0.017	3.933AspAsp: 3.933 ± 0.061	3.488AspGlu: 3.488 ± 0.054	1.385AspPhe: 1.385 ± 0.032	6.211AspGly: 6.211 ± 0.069	1.488AspHis: 1.488 ± 0.032	1.917AspIle: 1.917 ± 0.043	0.74AspLys: 0.74 ± 0.027	7.061AspLeu: 7.061 ± 0.075	0.693AspMet: 0.693 ± 0.02	0.891AspAsn: 0.891 ± 0.026	5.017AspPro: 5.017 ± 0.071	1.625AspGln: 1.625 ± 0.035	5.607AspArg: 5.607 ± 0.053	2.413AspSer: 2.413 ± 0.045	2.951AspThr: 2.951 ± 0.041	5.137AspVal: 5.137 ± 0.063	0.819AspTrp: 0.819 ± 0.022	1.07AspTyr: 1.07 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	6.231GluAla: 6.231 ± 0.079	0.32GluCys: 0.32 ± 0.015	2.317GluAsp: 2.317 ± 0.04	2.463GluGlu: 2.463 ± 0.044	1.374GluPhe: 1.374 ± 0.035	3.231GluGly: 3.231 ± 0.048	1.375GluHis: 1.375 ± 0.033	2.587GluIle: 2.587 ± 0.049	1.051GluLys: 1.051 ± 0.036	5.82GluLeu: 5.82 ± 0.086	0.789GluMet: 0.789 ± 0.025	0.929GluAsn: 0.929 ± 0.025	3.157GluPro: 3.157 ± 0.041	1.88GluGln: 1.88 ± 0.038	5.075GluArg: 5.075 ± 0.069	2.247GluSer: 2.247 ± 0.043	2.629GluThr: 2.629 ± 0.045	4.447GluVal: 4.447 ± 0.06	0.65GluTrp: 0.65 ± 0.022	0.899GluTyr: 0.899 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.603PheAla: 3.603 ± 0.053	0.259PheCys: 0.259 ± 0.013	2.052PheAsp: 2.052 ± 0.041	1.202PheGlu: 1.202 ± 0.033	0.84PhePhe: 0.84 ± 0.027	2.969PheGly: 2.969 ± 0.051	0.619PheHis: 0.619 ± 0.022	0.721PheIle: 0.721 ± 0.024	0.313PheLys: 0.313 ± 0.016	2.554PheLeu: 2.554 ± 0.042	0.321PheMet: 0.321 ± 0.018	0.436PheAsn: 0.436 ± 0.017	1.422PhePro: 1.422 ± 0.032	0.61PheGln: 0.61 ± 0.021	1.861PheArg: 1.861 ± 0.039	1.346PheSer: 1.346 ± 0.033	1.863PheThr: 1.863 ± 0.033	2.315PheVal: 2.315 ± 0.04	0.357PheTrp: 0.357 ± 0.016	0.528PheTyr: 0.528 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	10.699GlyAla: 10.699 ± 0.103	0.895GlyCys: 0.895 ± 0.027	5.007GlyAsp: 5.007 ± 0.058	4.538GlyGlu: 4.538 ± 0.06	2.727GlyPhe: 2.727 ± 0.042	9.33GlyGly: 9.33 ± 0.116	2.292GlyHis: 2.292 ± 0.038	3.482GlyIle: 3.482 ± 0.056	1.747GlyLys: 1.747 ± 0.043	9.421GlyLeu: 9.421 ± 0.09	1.865GlyMet: 1.865 ± 0.04	1.57GlyAsn: 1.57 ± 0.036	6.443GlyPro: 6.443 ± 0.096	2.814GlyGln: 2.814 ± 0.043	9.357GlyArg: 9.357 ± 0.106	5.742GlySer: 5.742 ± 0.068	5.894GlyThr: 5.894 ± 0.082	7.737GlyVal: 7.737 ± 0.091	1.794GlyTrp: 1.794 ± 0.038	2.16GlyTyr: 2.16 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.715HisAla: 2.715 ± 0.044	0.203HisCys: 0.203 ± 0.012	1.436HisAsp: 1.436 ± 0.032	1.043HisGlu: 1.043 ± 0.028	0.529HisPhe: 0.529 ± 0.02	2.339HisGly: 2.339 ± 0.046	0.77HisHis: 0.77 ± 0.025	0.659HisIle: 0.659 ± 0.02	0.221HisLys: 0.221 ± 0.012	2.447HisLeu: 2.447 ± 0.041	0.257HisMet: 0.257 ± 0.014	0.385HisAsn: 0.385 ± 0.017	2.033HisPro: 2.033 ± 0.043	0.679HisGln: 0.679 ± 0.023	2.407HisArg: 2.407 ± 0.041	1.04HisSer: 1.04 ± 0.026	1.172HisThr: 1.172 ± 0.037	1.66HisVal: 1.66 ± 0.034	0.309HisTrp: 0.309 ± 0.014	0.447HisTyr: 0.447 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	4.862IleAla: 4.862 ± 0.071	0.317IleCys: 0.317 ± 0.015	2.553IleAsp: 2.553 ± 0.045	2.078IleGlu: 2.078 ± 0.042	0.869IlePhe: 0.869 ± 0.026	3.68IleGly: 3.68 ± 0.052	0.735IleHis: 0.735 ± 0.022	1.322IleIle: 1.322 ± 0.034	0.54IleLys: 0.54 ± 0.02	2.902IleLeu: 2.902 ± 0.042	0.528IleMet: 0.528 ± 0.018	0.745IleAsn: 0.745 ± 0.022	2.043IlePro: 2.043 ± 0.038	0.717IleGln: 0.717 ± 0.022	2.836IleArg: 2.836 ± 0.046	1.945IleSer: 1.945 ± 0.047	2.127IleThr: 2.127 ± 0.043	3.293IleVal: 3.293 ± 0.047	0.371IleTrp: 0.371 ± 0.016	0.657IleTyr: 0.657 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	1.882LysAla: 1.882 ± 0.045	0.078LysCys: 0.078 ± 0.007	0.754LysAsp: 0.754 ± 0.028	0.711LysGlu: 0.711 ± 0.027	0.309LysPhe: 0.309 ± 0.014	1.152LysGly: 1.152 ± 0.035	0.288LysHis: 0.288 ± 0.013	0.91LysIle: 0.91 ± 0.026	0.475LysLys: 0.475 ± 0.024	1.418LysLeu: 1.418 ± 0.04	0.259LysMet: 0.259 ± 0.014	0.363LysAsn: 0.363 ± 0.017	0.979LysPro: 0.979 ± 0.028	0.45LysGln: 0.45 ± 0.018	1.102LysArg: 1.102 ± 0.03	0.79LysSer: 0.79 ± 0.027	0.968LysThr: 0.968 ± 0.027	1.396LysVal: 1.396 ± 0.036	0.149LysTrp: 0.149 ± 0.011	0.294LysTyr: 0.294 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	16.256LeuAla: 16.256 ± 0.142	0.862LeuCys: 0.862 ± 0.023	6.901LeuAsp: 6.901 ± 0.087	4.076LeuGlu: 4.076 ± 0.065	2.527LeuPhe: 2.527 ± 0.047	8.934LeuGly: 8.934 ± 0.095	2.19LeuHis: 2.19 ± 0.041	3.278LeuIle: 3.278 ± 0.053	1.178LeuLys: 1.178 ± 0.027	10.964LeuLeu: 10.964 ± 0.124	1.315LeuMet: 1.315 ± 0.03	1.444LeuAsn: 1.444 ± 0.036	6.628LeuPro: 6.628 ± 0.077	1.8LeuGln: 1.8 ± 0.037	9.391LeuArg: 9.391 ± 0.09	5.103LeuSer: 5.103 ± 0.067	6.607LeuThr: 6.607 ± 0.065	9.352LeuVal: 9.352 ± 0.087	1.165LeuTrp: 1.165 ± 0.034	1.601LeuTyr: 1.601 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.032MetAla: 2.032 ± 0.033	0.135MetCys: 0.135 ± 0.011	0.722MetAsp: 0.722 ± 0.021	0.585MetGlu: 0.585 ± 0.018	0.469MetPhe: 0.469 ± 0.018	1.118MetGly: 1.118 ± 0.029	0.285MetHis: 0.285 ± 0.014	0.891MetIle: 0.891 ± 0.025	0.292MetLys: 0.292 ± 0.015	1.657MetLeu: 1.657 ± 0.032	0.288MetMet: 0.288 ± 0.017	0.419MetAsn: 0.419 ± 0.019	1.112MetPro: 1.112 ± 0.028	0.364MetGln: 0.364 ± 0.016	1.424MetArg: 1.424 ± 0.033	1.204MetSer: 1.204 ± 0.029	1.452MetThr: 1.452 ± 0.031	1.307MetVal: 1.307 ± 0.034	0.194MetTrp: 0.194 ± 0.01	0.265MetTyr: 0.265 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.005AsnAla: 2.005 ± 0.041	0.128AsnCys: 0.128 ± 0.01	0.868AsnAsp: 0.868 ± 0.025	0.717AsnGlu: 0.717 ± 0.022	0.387AsnPhe: 0.387 ± 0.015	1.609AsnGly: 1.609 ± 0.035	0.372AsnHis: 0.372 ± 0.017	0.674AsnIle: 0.674 ± 0.024	0.264AsnLys: 0.264 ± 0.015	1.737AsnLeu: 1.737 ± 0.037	0.257AsnMet: 0.257 ± 0.015	0.349AsnAsn: 0.349 ± 0.016	1.465AsnPro: 1.465 ± 0.035	0.476AsnGln: 0.476 ± 0.017	1.45AsnArg: 1.45 ± 0.032	0.782AsnSer: 0.782 ± 0.027	1.007AsnThr: 1.007 ± 0.03	1.268AsnVal: 1.268 ± 0.032	0.229AsnTrp: 0.229 ± 0.013	0.333AsnTyr: 0.333 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	10.281ProAla: 10.281 ± 0.117	0.387ProCys: 0.387 ± 0.017	4.983ProAsp: 4.983 ± 0.059	3.491ProGlu: 3.491 ± 0.049	1.56ProPhe: 1.56 ± 0.03	7.867ProGly: 7.867 ± 0.112	1.408ProHis: 1.408 ± 0.035	1.716ProIle: 1.716 ± 0.031	0.873ProLys: 0.873 ± 0.028	5.137ProLeu: 5.137 ± 0.06	1.045ProMet: 1.045 ± 0.027	0.928ProAsn: 0.928 ± 0.028	4.945ProPro: 4.945 ± 0.096	1.435ProGln: 1.435 ± 0.032	5.128ProArg: 5.128 ± 0.078	3.919ProSer: 3.919 ± 0.067	4.196ProThr: 4.196 ± 0.076	5.903ProVal: 5.903 ± 0.068	0.923ProTrp: 0.923 ± 0.027	1.104ProTyr: 1.104 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.63GlnAla: 3.63 ± 0.055	0.163GlnCys: 0.163 ± 0.01	1.109GlnAsp: 1.109 ± 0.028	1.119GlnGlu: 1.119 ± 0.029	0.62GlnPhe: 0.62 ± 0.02	1.807GlnGly: 1.807 ± 0.036	0.573GlnHis: 0.573 ± 0.025	1.197GlnIle: 1.197 ± 0.027	0.385GlnLys: 0.385 ± 0.017	2.806GlnLeu: 2.806 ± 0.045	0.439GlnMet: 0.439 ± 0.016	0.469GlnAsn: 0.469 ± 0.02	1.938GlnPro: 1.938 ± 0.051	0.932GlnGln: 0.932 ± 0.03	2.438GlnArg: 2.438 ± 0.044	1.05GlnSer: 1.05 ± 0.027	1.303GlnThr: 1.303 ± 0.03	2.503GlnVal: 2.503 ± 0.041	0.381GlnTrp: 0.381 ± 0.018	0.462GlnTyr: 0.462 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	10.991ArgAla: 10.991 ± 0.095	0.779ArgCys: 0.779 ± 0.026	4.817ArgAsp: 4.817 ± 0.063	4.47ArgGlu: 4.47 ± 0.061	2.532ArgPhe: 2.532 ± 0.048	6.935ArgGly: 6.935 ± 0.086	2.435ArgHis: 2.435 ± 0.037	3.609ArgIle: 3.609 ± 0.064	1.289ArgLys: 1.289 ± 0.038	9.824ArgLeu: 9.824 ± 0.101	1.893ArgMet: 1.893 ± 0.039	1.411ArgAsn: 1.411 ± 0.032	6.529ArgPro: 6.529 ± 0.093	2.581ArgGln: 2.581 ± 0.04	10.158ArgArg: 10.158 ± 0.121	5.013ArgSer: 5.013 ± 0.065	5.225ArgThr: 5.225 ± 0.053	6.748ArgVal: 6.748 ± 0.078	1.646ArgTrp: 1.646 ± 0.042	1.953ArgTyr: 1.953 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.025SerAla: 7.025 ± 0.081	0.448SerCys: 0.448 ± 0.019	2.794SerAsp: 2.794 ± 0.045	2.151SerGlu: 2.151 ± 0.042	1.52SerPhe: 1.52 ± 0.035	5.92SerGly: 5.92 ± 0.071	1.01SerHis: 1.01 ± 0.025	1.681SerIle: 1.681 ± 0.036	0.743SerLys: 0.743 ± 0.026	4.749SerLeu: 4.749 ± 0.059	1.051SerMet: 1.051 ± 0.026	0.834SerAsn: 0.834 ± 0.03	3.911SerPro: 3.911 ± 0.061	1.225SerGln: 1.225 ± 0.032	4.617SerArg: 4.617 ± 0.053	3.31SerSer: 3.31 ± 0.055	3.411SerThr: 3.411 ± 0.058	4.21SerVal: 4.21 ± 0.054	0.95SerTrp: 0.95 ± 0.024	1.143SerTyr: 1.143 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	8.433ThrAla: 8.433 ± 0.106	0.481ThrCys: 0.481 ± 0.02	3.466ThrAsp: 3.466 ± 0.057	2.837ThrGlu: 2.837 ± 0.049	1.573ThrPhe: 1.573 ± 0.042	6.583ThrGly: 6.583 ± 0.078	1.192ThrHis: 1.192 ± 0.03	2.188ThrIle: 2.188 ± 0.04	0.854ThrLys: 0.854 ± 0.027	5.67ThrLeu: 5.67 ± 0.062	0.973ThrMet: 0.973 ± 0.027	0.965ThrAsn: 0.965 ± 0.028	4.221ThrPro: 4.221 ± 0.07	1.207ThrGln: 1.207 ± 0.031	4.587ThrArg: 4.587 ± 0.055	3.465ThrSer: 3.465 ± 0.058	4.037ThrThr: 4.037 ± 0.066	5.872ThrVal: 5.872 ± 0.063	0.82ThrTrp: 0.82 ± 0.023	1.06ThrTyr: 1.06 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	11.561ValAla: 11.561 ± 0.118	0.807ValCys: 0.807 ± 0.026	5.644ValAsp: 5.644 ± 0.065	4.631ValGlu: 4.631 ± 0.063	2.321ValPhe: 2.321 ± 0.044	7.415ValGly: 7.415 ± 0.081	1.97ValHis: 1.97 ± 0.038	3.131ValIle: 3.131 ± 0.05	1.247ValLys: 1.247 ± 0.031	9.352ValLeu: 9.352 ± 0.094	1.29ValMet: 1.29 ± 0.03	1.587ValAsn: 1.587 ± 0.034	5.565ValPro: 5.565 ± 0.075	1.799ValGln: 1.799 ± 0.036	7.503ValArg: 7.503 ± 0.072	4.508ValSer: 4.508 ± 0.055	5.697ValThr: 5.697 ± 0.08	8.476ValVal: 8.476 ± 0.12	1.041ValTrp: 1.041 ± 0.025	1.395ValTyr: 1.395 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.547TrpAla: 1.547 ± 0.029	0.173TrpCys: 0.173 ± 0.01	0.764TrpAsp: 0.764 ± 0.029	0.647TrpGlu: 0.647 ± 0.021	0.45TrpPhe: 0.45 ± 0.018	0.879TrpGly: 0.879 ± 0.028	0.388TrpHis: 0.388 ± 0.015	0.563TrpIle: 0.563 ± 0.022	0.277TrpLys: 0.277 ± 0.015	1.712TrpLeu: 1.712 ± 0.048	0.261TrpMet: 0.261 ± 0.013	0.326TrpAsn: 0.326 ± 0.015	0.894TrpPro: 0.894 ± 0.022	0.506TrpGln: 0.506 ± 0.021	1.499TrpArg: 1.499 ± 0.034	0.946TrpSer: 0.946 ± 0.027	0.933TrpThr: 0.933 ± 0.029	0.979TrpVal: 0.979 ± 0.023	0.333TrpTrp: 0.333 ± 0.018	0.283TrpTyr: 0.283 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.216TyrAla: 2.216 ± 0.04	0.181TyrCys: 0.181 ± 0.011	1.217TyrAsp: 1.217 ± 0.034	0.928TyrGlu: 0.928 ± 0.029	0.555TyrPhe: 0.555 ± 0.021	1.816TyrGly: 1.816 ± 0.043	0.403TyrHis: 0.403 ± 0.015	0.462TyrIle: 0.462 ± 0.019	0.257TyrLys: 0.257 ± 0.014	2.273TyrLeu: 2.273 ± 0.042	0.182TyrMet: 0.182 ± 0.011	0.327TyrAsn: 0.327 ± 0.014	1.177TyrPro: 1.177 ± 0.034	0.657TyrGln: 0.657 ± 0.022	1.883TyrArg: 1.883 ± 0.037	0.887TyrSer: 0.887 ± 0.025	0.963TyrThr: 0.963 ± 0.026	1.429TyrVal: 1.429 ± 0.035	0.294TyrTrp: 0.294 ± 0.014	0.397TyrTyr: 0.397 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4441 proteins (1512431 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---