Rosellinia necatrix hypovirus 1
Average proteome isoelectric point is 7.28
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A2Z5WQ87|A0A2Z5WQ87_9VIRU RNA-directed RNA polymerase OS=Rosellinia necatrix hypovirus 1 OX=2032989 GN=RdRP PE=4 SV=1
MM1 pKa = 7.72 NPGQKK6 pKa = 9.63 RR7 pKa = 11.84 GSRR10 pKa = 11.84 PPQTPNYY17 pKa = 8.57 SRR19 pKa = 11.84 SSSRR23 pKa = 11.84 STTSSVGLTSEE34 pKa = 4.04 PQMLLDD40 pKa = 4.34 RR41 pKa = 11.84 FSAQLAEE48 pKa = 4.39 QEE50 pKa = 4.21 RR51 pKa = 11.84 HH52 pKa = 5.71 LADD55 pKa = 3.59 PTSRR59 pKa = 11.84 PDD61 pKa = 3.11 WPICCFCPSKK71 pKa = 11.0 LSVDD75 pKa = 3.76 DD76 pKa = 3.64 VTGKK80 pKa = 10.15 IVICRR85 pKa = 11.84 ACVNSHH91 pKa = 7.02 DD92 pKa = 4.25 EE93 pKa = 3.94 IFRR96 pKa = 11.84 QLEE99 pKa = 4.31 AQCSPVLEE107 pKa = 4.59 APSPRR112 pKa = 11.84 TVLAPIEE119 pKa = 4.34 EE120 pKa = 4.37 EE121 pKa = 4.19 PEE123 pKa = 4.07 PVVSEE128 pKa = 4.16 SRR130 pKa = 11.84 VGIVIPVVEE139 pKa = 4.97 DD140 pKa = 3.54 VPAPVVEE147 pKa = 4.41 PLPFLTEE154 pKa = 3.67 YY155 pKa = 10.78 AAPRR159 pKa = 11.84 WEE161 pKa = 4.14 QEE163 pKa = 3.9 SLLVGGSVSRR173 pKa = 11.84 PVINFPKK180 pKa = 9.56 VHH182 pKa = 6.36 SPSVAEE188 pKa = 3.97 TSRR191 pKa = 11.84 APEE194 pKa = 4.08 LVFTAPKK201 pKa = 8.15 TTDD204 pKa = 2.96 NVTITLVVTVPGGDD218 pKa = 2.99 VDD220 pKa = 3.72 KK221 pKa = 10.51 WLKK224 pKa = 10.55 GPSRR228 pKa = 11.84 MSNLDD233 pKa = 3.34 WILRR237 pKa = 11.84 EE238 pKa = 3.42 HH239 pKa = 7.15 DD240 pKa = 3.2 RR241 pKa = 11.84 RR242 pKa = 11.84 IEE244 pKa = 3.9 RR245 pKa = 11.84 EE246 pKa = 3.72 NRR248 pKa = 11.84 SLIRR252 pKa = 11.84 ASLYY256 pKa = 10.16 KK257 pKa = 10.35 VRR259 pKa = 11.84 SKK261 pKa = 11.1 AYY263 pKa = 8.17 WADD266 pKa = 3.44 LVSSMKK272 pKa = 9.9 EE273 pKa = 3.43 RR274 pKa = 11.84 RR275 pKa = 11.84 AVQQKK280 pKa = 10.34 AYY282 pKa = 8.92 RR283 pKa = 11.84 TARR286 pKa = 11.84 DD287 pKa = 3.32 QSRR290 pKa = 11.84 TAISAPLVLANKK302 pKa = 8.54 FSCLTEE308 pKa = 4.0 DD309 pKa = 3.39 EE310 pKa = 5.47 RR311 pKa = 11.84 EE312 pKa = 4.11 DD313 pKa = 4.29 FYY315 pKa = 11.57 HH316 pKa = 7.17 GIIPAVRR323 pKa = 11.84 PSLPTRR329 pKa = 11.84 SWPKK333 pKa = 9.91 RR334 pKa = 11.84 KK335 pKa = 9.38 RR336 pKa = 11.84 APIPAEE342 pKa = 4.12 KK343 pKa = 10.01 KK344 pKa = 9.93 KK345 pKa = 10.98 SPPAPFEE352 pKa = 4.24 RR353 pKa = 11.84 DD354 pKa = 3.19 PLLLEE359 pKa = 4.53 RR360 pKa = 11.84 LHH362 pKa = 7.0 KK363 pKa = 10.75 LLEE366 pKa = 4.28 HH367 pKa = 7.27 LLNQRR372 pKa = 11.84 RR373 pKa = 11.84 KK374 pKa = 8.98 KK375 pKa = 9.18 IHH377 pKa = 6.38 RR378 pKa = 11.84 KK379 pKa = 6.58 VTVSRR384 pKa = 11.84 SSCEE388 pKa = 3.91 RR389 pKa = 11.84 MSCPSTGTLLSTNTVKK405 pKa = 10.68 RR406 pKa = 11.84 AKK408 pKa = 10.04 ADD410 pKa = 3.43 NVGLVGIEE418 pKa = 4.24 SNPGPEE424 pKa = 3.92 YY425 pKa = 10.81 SGPLDD430 pKa = 3.8 ANFSISLTATLPCLRR445 pKa = 11.84 VNYY448 pKa = 10.11 SQLQAFDD455 pKa = 4.07 DD456 pKa = 4.33 AEE458 pKa = 4.15 MAEE461 pKa = 4.44 LMRR464 pKa = 11.84 CGYY467 pKa = 8.32 ATKK470 pKa = 10.66 SPWNEE475 pKa = 3.52 VSILCSWIXKK485 pKa = 7.89 GQSVLGWVFSDD496 pKa = 3.82 RR497 pKa = 11.84 SHH499 pKa = 6.72 RR500 pKa = 11.84 AAAGSHH506 pKa = 4.76 KK507 pKa = 10.3 VAWYY511 pKa = 9.97 QPTLHH516 pKa = 7.79 VYY518 pKa = 7.6 MQQGYY523 pKa = 6.74 TGKK526 pKa = 10.49 LLAYY530 pKa = 10.12 RR531 pKa = 11.84 FNCYY535 pKa = 7.49 EE536 pKa = 3.76 WSKK539 pKa = 10.5 QASTAQDD546 pKa = 3.29 PKK548 pKa = 10.85 AIPGLEE554 pKa = 3.77 QSVAEE559 pKa = 5.06 DD560 pKa = 3.7 FTDD563 pKa = 4.66 GNWSTWFQLLQKK575 pKa = 10.18 YY576 pKa = 9.3 QDD578 pKa = 3.52 SLRR581 pKa = 11.84 ACKK584 pKa = 10.34 KK585 pKa = 10.25 EE586 pKa = 3.39 ISEE589 pKa = 4.19 LKK591 pKa = 10.32 KK592 pKa = 10.37 PEE594 pKa = 4.07 GARR597 pKa = 11.84 KK598 pKa = 8.38 HH599 pKa = 6.37 CKK601 pKa = 8.24 HH602 pKa = 6.3 HH603 pKa = 6.93 VYY605 pKa = 11.08 ADD607 pKa = 3.98 DD608 pKa = 4.12 FTLLPQTQLEE618 pKa = 4.32 EE619 pKa = 4.11 FRR621 pKa = 11.84 NLSLNRR627 pKa = 11.84 TDD629 pKa = 6.69 FIDD632 pKa = 3.06 IMNRR636 pKa = 11.84 LTSPSVYY643 pKa = 8.87 TSPYY647 pKa = 10.08 IYY649 pKa = 9.59 DD650 pKa = 4.3 TIANLDD656 pKa = 3.65 NQIGNNLTRR665 pKa = 11.84 YY666 pKa = 9.38 RR667 pKa = 11.84 SHH669 pKa = 8.51 SEE671 pKa = 3.29 IKK673 pKa = 9.73 IGNRR677 pKa = 11.84 IHH679 pKa = 6.57 SCEE682 pKa = 4.28 DD683 pKa = 3.14 APATTITNGLDD694 pKa = 3.44 FEE696 pKa = 4.91 SGSDD700 pKa = 4.43 RR701 pKa = 11.84 NDD703 pKa = 3.01 QCSTDD708 pKa = 4.1 GIVTRR713 pKa = 11.84 LRR715 pKa = 11.84 HH716 pKa = 6.01 DD717 pKa = 3.61 AQDD720 pKa = 3.33 PXVRR724 pKa = 11.84 DD725 pKa = 3.65 LSXEE729 pKa = 4.08 GLHH732 pKa = 6.52 GVNFDD737 pKa = 4.05 LSVSPRR743 pKa = 11.84 SLPRR747 pKa = 11.84 GTLEE751 pKa = 4.0 FLASINYY758 pKa = 9.42 DD759 pKa = 3.33 HH760 pKa = 6.97 VPPRR764 pKa = 11.84 DD765 pKa = 3.21 IVLTANRR772 pKa = 11.84 MWLNDD777 pKa = 3.97 LPGSPYY783 pKa = 10.02 IIEE786 pKa = 4.4 LRR788 pKa = 11.84 STTDD792 pKa = 2.72 ASHH795 pKa = 6.64 IVYY798 pKa = 10.06 DD799 pKa = 4.38 RR800 pKa = 11.84 KK801 pKa = 10.62 RR802 pKa = 11.84 KK803 pKa = 7.64 TKK805 pKa = 9.95 MIIYY809 pKa = 8.9 LQGVEE814 pKa = 4.59 GKK816 pKa = 9.47 QLQLLRR822 pKa = 11.84 FEE824 pKa = 4.94 PLFHH828 pKa = 6.99 LKK830 pKa = 8.28 HH831 pKa = 5.24 TARR834 pKa = 11.84 ALVLNGGRR842 pKa = 11.84 MGSKK846 pKa = 8.83 WFAPYY851 pKa = 9.62 RR852 pKa = 11.84 QEE854 pKa = 4.28 YY855 pKa = 7.14 PTPQYY860 pKa = 9.84 EE861 pKa = 4.33 LPYY864 pKa = 9.69 VYY866 pKa = 9.61 PVSAGCCWIKK876 pKa = 10.5 RR877 pKa = 11.84 ADD879 pKa = 3.85 MEE881 pKa = 4.32 LHH883 pKa = 6.05 KK884 pKa = 10.86 VDD886 pKa = 3.24 WYY888 pKa = 11.03 KK889 pKa = 11.3 AFSGWSGVYY898 pKa = 10.34 GVDD901 pKa = 2.98 EE902 pKa = 4.44 NMLARR907 pKa = 11.84 YY908 pKa = 8.7 EE909 pKa = 4.12 GFMFLRR915 pKa = 11.84 GRR917 pKa = 11.84 SFSTSTHH924 pKa = 6.39 AGTNVPVTTHH934 pKa = 7.14 FIDD937 pKa = 4.81 ADD939 pKa = 3.62 THH941 pKa = 4.12 QTYY944 pKa = 10.02 FSAYY948 pKa = 6.36 WWSAKK953 pKa = 8.75 IARR956 pKa = 11.84 RR957 pKa = 11.84 INSLTFSHH965 pKa = 5.99 SQHH968 pKa = 6.15 WDD970 pKa = 3.35 DD971 pKa = 5.66 VKK973 pKa = 11.33 LLLPSQTPYY982 pKa = 11.08 EE983 pKa = 4.61 HH984 pKa = 7.54 DD985 pKa = 4.4 LDD987 pKa = 4.15 PSKK990 pKa = 11.16 LFGQLPGRR998 pKa = 11.84 KK999 pKa = 8.73 VPYY1002 pKa = 10.18 DD1003 pKa = 3.84 RR1004 pKa = 11.84 LPTLAILDD1012 pKa = 4.49 DD1013 pKa = 4.29 GGKK1016 pKa = 7.91 TLLCNAYY1023 pKa = 10.41 DD1024 pKa = 3.64 RR1025 pKa = 11.84 FVTPTHH1031 pKa = 6.1 SKK1033 pKa = 9.06 RR1034 pKa = 11.84 VIYY1037 pKa = 9.81 YY1038 pKa = 8.18 GHH1040 pKa = 7.41 AALTPAMVDD1049 pKa = 3.84 FLLTRR1054 pKa = 11.84 DD1055 pKa = 3.65 IILVVAEE1062 pKa = 4.54 HH1063 pKa = 6.7 WCASFDD1069 pKa = 3.56 TSRR1072 pKa = 11.84 FDD1074 pKa = 3.97 IKK1076 pKa = 10.08 VQRR1079 pKa = 11.84 PINARR1084 pKa = 11.84 RR1085 pKa = 11.84 KK1086 pKa = 9.23 VSYY1089 pKa = 10.18 HH1090 pKa = 4.95 SCEE1093 pKa = 4.17 NQTSRR1098 pKa = 11.84 SPLSPNDD1105 pKa = 3.4 FFNEE1109 pKa = 4.17 CVTFANTHH1117 pKa = 6.5 LEE1119 pKa = 4.19 TKK1121 pKa = 9.84 IRR1123 pKa = 11.84 RR1124 pKa = 11.84 DD1125 pKa = 3.14 PRR1127 pKa = 11.84 LEE1129 pKa = 3.85 VSEE1132 pKa = 4.65 ANPGAKK1138 pKa = 9.55 LVFGYY1143 pKa = 10.8 DD1144 pKa = 3.63 VFPLGYY1150 pKa = 10.5 AKK1152 pKa = 10.48 DD1153 pKa = 3.42 SRR1155 pKa = 11.84 FRR1157 pKa = 11.84 VTLEE1161 pKa = 3.82 NGCKK1165 pKa = 9.67 VFKK1168 pKa = 10.8 ANQPDD1173 pKa = 3.74 ISTLRR1178 pKa = 11.84 SMSRR1182 pKa = 11.84 VWADD1186 pKa = 3.02 PATFYY1191 pKa = 11.63 AEE1193 pKa = 4.31 LPQFIKK1199 pKa = 10.47 PVAPEE1204 pKa = 3.87 PVLNRR1209 pKa = 11.84 ATINWYY1215 pKa = 10.2 GYY1217 pKa = 9.3 VYY1219 pKa = 10.6 SIFSLLRR1226 pKa = 11.84 GKK1228 pKa = 10.33 AIYY1231 pKa = 8.96 PIIFVALMPAVLARR1245 pKa = 11.84 RR1246 pKa = 11.84 QIVSAISTQTVNASRR1261 pKa = 11.84 PVWNAYY1267 pKa = 7.56 QASGNTYY1274 pKa = 7.79 QTLNINHH1281 pKa = 7.63 IYY1283 pKa = 7.93 TQPLQATGNFSKK1295 pKa = 10.4 FIWSLGIWVRR1305 pKa = 11.84 IARR1308 pKa = 11.84 QFGNVFYY1315 pKa = 11.21 GLLDD1319 pKa = 3.55 TAHH1322 pKa = 7.42 EE1323 pKa = 4.12 IGIVLVTWLAAVIFVFGIWFHH1344 pKa = 5.54 LWGYY1348 pKa = 9.38 KK1349 pKa = 9.02 YY1350 pKa = 10.42 QGIVPTILDD1359 pKa = 4.06 DD1360 pKa = 3.85 NALFSISDD1368 pKa = 3.41 NSTPVTDD1375 pKa = 4.12 EE1376 pKa = 4.62 DD1377 pKa = 4.59 LSEE1380 pKa = 4.23 ALCIVTYY1387 pKa = 7.26 GTRR1390 pKa = 11.84 GDD1392 pKa = 5.05 HH1393 pKa = 7.61 IPMQYY1398 pKa = 10.38 FGRR1401 pKa = 11.84 LAALYY1406 pKa = 9.6 GVRR1409 pKa = 11.84 THH1411 pKa = 6.98 NYY1413 pKa = 8.06 QAHH1416 pKa = 6.42 LGDD1419 pKa = 4.18 NKK1421 pKa = 10.2 TLEE1424 pKa = 4.07 QLRR1427 pKa = 11.84 RR1428 pKa = 11.84 ADD1430 pKa = 3.61 FTGLRR1435 pKa = 11.84 LRR1437 pKa = 11.84 YY1438 pKa = 9.38 LEE1440 pKa = 5.43 LMTTSLLPYY1449 pKa = 8.61 KK1450 pKa = 10.4 QIMQPFVHH1458 pKa = 6.86 LGGKK1462 pKa = 6.33 VTSYY1466 pKa = 10.19 TLSPSEE1472 pKa = 4.7 AFVHH1476 pKa = 5.98 PLNFGGNPTLFSKK1489 pKa = 10.57 FASFANRR1496 pKa = 11.84 FFNPDD1501 pKa = 3.24 LRR1503 pKa = 11.84 VGALKK1508 pKa = 10.62 EE1509 pKa = 4.35 SVLPRR1514 pKa = 11.84 SPDD1517 pKa = 3.15 GKK1519 pKa = 10.61 KK1520 pKa = 10.23 LLRR1523 pKa = 11.84 MLPAVTAGPEE1533 pKa = 4.14 AYY1535 pKa = 8.61 THH1537 pKa = 6.2 GSEE1540 pKa = 4.29 DD1541 pKa = 3.66 ASVIPYY1547 pKa = 9.28 GVKK1550 pKa = 10.03 LRR1552 pKa = 11.84 CPKK1555 pKa = 10.51 LEE1557 pKa = 4.52 SGDD1560 pKa = 3.69 HH1561 pKa = 5.38 QIVMRR1566 pKa = 11.84 KK1567 pKa = 8.67 YY1568 pKa = 9.59 SGIYY1572 pKa = 8.44 SHH1574 pKa = 7.07 AGAGTLQTILMSGIPVEE1591 pKa = 4.39 RR1592 pKa = 11.84 RR1593 pKa = 11.84 HH1594 pKa = 6.23 ICDD1597 pKa = 3.08 INIDD1601 pKa = 3.63 RR1602 pKa = 11.84 WYY1604 pKa = 9.41 HH1605 pKa = 5.94 TIPTLNDD1612 pKa = 2.94 VTEE1615 pKa = 4.36 RR1616 pKa = 11.84 SPYY1619 pKa = 10.25 VFLGYY1624 pKa = 10.48 LIVKK1628 pKa = 10.02 GFDD1631 pKa = 3.43 LKK1633 pKa = 10.92 ISLWDD1638 pKa = 3.27 KK1639 pKa = 10.73 FLAIGIWLFTTCTAKK1654 pKa = 10.87 SFVDD1658 pKa = 4.81 TIAWGYY1664 pKa = 9.7 RR1665 pKa = 11.84 YY1666 pKa = 10.09 YY1667 pKa = 11.34 AVFYY1671 pKa = 9.32 GFRR1674 pKa = 11.84 SILHH1678 pKa = 4.8 QVILVILTFPSIAHH1692 pKa = 6.18 FFGVTWLKK1700 pKa = 11.12 LPLCAIASALIDD1712 pKa = 4.19 APILTQMGSIWTLLYY1727 pKa = 9.42 MAYY1730 pKa = 9.98 QYY1732 pKa = 11.67 AQFVPKK1738 pKa = 10.07 VISEE1742 pKa = 3.93 ISSWLDD1748 pKa = 3.17 TRR1750 pKa = 11.84 SEE1752 pKa = 4.05 LVMTSNEE1759 pKa = 4.15 SFPAPFGHH1767 pKa = 7.13 WYY1769 pKa = 10.38 VVDD1772 pKa = 3.44 HH1773 pKa = 6.79 RR1774 pKa = 11.84 SGRR1777 pKa = 11.84 RR1778 pKa = 11.84 YY1779 pKa = 9.49 EE1780 pKa = 4.26 GSFSGSKK1787 pKa = 9.82 GWHH1790 pKa = 5.3 QKK1792 pKa = 10.39 FGWIAHH1798 pKa = 4.94 TRR1800 pKa = 11.84 VFNNTDD1806 pKa = 3.19 MEE1808 pKa = 4.54 DD1809 pKa = 2.9 RR1810 pKa = 11.84 GYY1812 pKa = 11.18 YY1813 pKa = 7.1 QTLYY1817 pKa = 10.67 MFITALAFIVATACLCCFSHH1837 pKa = 6.87 PLISFSMVLVSIFLFAFVICEE1858 pKa = 3.88 PLYY1861 pKa = 10.82 QYY1863 pKa = 11.04 AQYY1866 pKa = 11.47 GSTQKK1871 pKa = 10.2 IKK1873 pKa = 10.63 KK1874 pKa = 8.73 EE1875 pKa = 3.75 YY1876 pKa = 10.07 RR1877 pKa = 11.84 IPLPFTSNTVEE1888 pKa = 4.01 RR1889 pKa = 11.84 MAAAYY1894 pKa = 9.45 ARR1896 pKa = 11.84 NEE1898 pKa = 4.17 DD1899 pKa = 3.44 LGGYY1903 pKa = 9.85 HH1904 pKa = 7.33 PFFNCQSLVIPLVYY1918 pKa = 10.57 DD1919 pKa = 3.33 STLFCAAFCTLVFLFTLTVLIPGWAAAVMKK1949 pKa = 9.79 PLVKK1953 pKa = 10.24 RR1954 pKa = 11.84 LSIRR1958 pKa = 11.84 IWDD1961 pKa = 3.69 VSLEE1965 pKa = 4.75 DD1966 pKa = 3.67 ILEE1969 pKa = 4.77 DD1970 pKa = 3.35 IQRR1973 pKa = 11.84 STNFAAAPPVKK1984 pKa = 9.77 TEE1986 pKa = 4.4 NVPSDD1991 pKa = 3.75 PSPTPFKK1998 pKa = 10.87 EE1999 pKa = 3.45 RR2000 pKa = 11.84 VQGYY2004 pKa = 8.7 RR2005 pKa = 11.84 EE2006 pKa = 3.86 AGIPEE2011 pKa = 4.09 VEE2013 pKa = 4.52 LPQDD2017 pKa = 3.4 EE2018 pKa = 4.31 QAEE2021 pKa = 4.44 LKK2023 pKa = 10.95 LIDD2026 pKa = 3.09 YY2027 pKa = 7.4 WTRR2030 pKa = 11.84 KK2031 pKa = 6.98 FHH2033 pKa = 6.54 EE2034 pKa = 4.74 PLDD2037 pKa = 3.57 IFEE2040 pKa = 4.51 QVQTLYY2046 pKa = 10.66 KK2047 pKa = 10.73 LSMDD2051 pKa = 3.84 PTQSHH2056 pKa = 7.06 PLSEE2060 pKa = 5.32 AEE2062 pKa = 4.15 AEE2064 pKa = 4.49 HH2065 pKa = 5.93 VRR2067 pKa = 11.84 AMTLAKK2073 pKa = 10.35 YY2074 pKa = 10.21 LEE2076 pKa = 4.2 HH2077 pKa = 6.69 HH2078 pKa = 6.22 VSEE2081 pKa = 4.82 EE2082 pKa = 4.03 EE2083 pKa = 4.24 VEE2085 pKa = 4.35 LEE2087 pKa = 3.83 ARR2089 pKa = 11.84 MPGATSIIHH2098 pKa = 6.31 SEE2100 pKa = 4.12 MPPSQNDD2107 pKa = 3.47 PTSPNAHH2114 pKa = 6.47 LWAKK2118 pKa = 10.11 FVGKK2122 pKa = 10.17 LDD2124 pKa = 3.69 EE2125 pKa = 5.43 FLSIWSGEE2133 pKa = 4.07 KK2134 pKa = 10.02 FVSDD2138 pKa = 4.08 IISWLRR2144 pKa = 11.84 NQRR2147 pKa = 11.84 FKK2149 pKa = 11.33 HH2150 pKa = 5.74 LGDD2153 pKa = 3.3 LAFRR2157 pKa = 11.84 VYY2159 pKa = 10.78 HH2160 pKa = 6.09 LLCFIGRR2167 pKa = 11.84 IVYY2170 pKa = 7.53 TTSFNAWRR2178 pKa = 11.84 VLNLGMTCFLTCIFPVEE2195 pKa = 3.78 EE2196 pKa = 4.05 AKK2198 pKa = 10.55 RR2199 pKa = 11.84 LKK2201 pKa = 10.47 SAWAFAGLTKK2211 pKa = 10.48 TPFLSTKK2218 pKa = 9.94 RR2219 pKa = 11.84 RR2220 pKa = 11.84 FVEE2223 pKa = 4.54 NIAWSTKK2230 pKa = 6.97 EE2231 pKa = 3.62 EE2232 pKa = 4.02 RR2233 pKa = 11.84 GDD2235 pKa = 3.6 FLEE2238 pKa = 5.15 SFTSMVDD2245 pKa = 3.71 EE2246 pKa = 4.7 INHH2249 pKa = 4.89 YY2250 pKa = 7.63 CQRR2253 pKa = 11.84 HH2254 pKa = 4.78 GAPGIEE2260 pKa = 4.41 LHH2262 pKa = 5.4 PQYY2265 pKa = 10.94 RR2266 pKa = 11.84 KK2267 pKa = 10.34 VNVGRR2272 pKa = 11.84 PVLDD2276 pKa = 4.47 DD2277 pKa = 3.85 EE2278 pKa = 4.59 QATLLGLNKK2287 pKa = 9.99 DD2288 pKa = 4.02 AYY2290 pKa = 10.01 VTDD2293 pKa = 3.55 QRR2295 pKa = 11.84 STDD2298 pKa = 3.74 FTRR2301 pKa = 11.84 SLRR2304 pKa = 11.84 EE2305 pKa = 3.45 KK2306 pKa = 9.22 GTPISADD2313 pKa = 3.17 TVYY2316 pKa = 9.98 LTDD2319 pKa = 4.42 KK2320 pKa = 10.8 IEE2322 pKa = 4.0 YY2323 pKa = 7.95 VQQSVRR2329 pKa = 11.84 RR2330 pKa = 11.84 YY2331 pKa = 7.6 IPRR2334 pKa = 11.84 YY2335 pKa = 9.18 EE2336 pKa = 4.81 PISHH2340 pKa = 6.75 EE2341 pKa = 4.57 DD2342 pKa = 3.0 KK2343 pKa = 11.21 LLAHH2347 pKa = 7.27 EE2348 pKa = 4.64 IAAEE2352 pKa = 4.1 FGSRR2356 pKa = 11.84 FPDD2359 pKa = 3.25 SFKK2362 pKa = 10.74 DD2363 pKa = 3.55 AKK2365 pKa = 10.09 TLTPRR2370 pKa = 11.84 QVQAYY2375 pKa = 8.61 YY2376 pKa = 9.61 KK2377 pKa = 10.37 AKK2379 pKa = 9.82 YY2380 pKa = 9.9 APGSPWISIYY2390 pKa = 10.52 KK2391 pKa = 9.75 SRR2393 pKa = 11.84 QALEE2397 pKa = 3.94 DD2398 pKa = 3.45 AGITKK2403 pKa = 10.6 ALFEE2407 pKa = 4.27 MVEE2410 pKa = 4.21 DD2411 pKa = 4.16 RR2412 pKa = 11.84 LASGKK2417 pKa = 10.33 YY2418 pKa = 8.77 PDD2420 pKa = 4.4 MYY2422 pKa = 10.68 HH2423 pKa = 6.42 KK2424 pKa = 10.83 AFVKK2428 pKa = 10.42 SQVVNLDD2435 pKa = 3.2 KK2436 pKa = 11.23 VINGNKK2442 pKa = 9.16 NVRR2445 pKa = 11.84 TVVAQEE2451 pKa = 3.67 LLTYY2455 pKa = 9.6 FMNMCMEE2462 pKa = 4.61 LEE2464 pKa = 4.13 RR2465 pKa = 11.84 NHH2467 pKa = 5.27 RR2468 pKa = 11.84 HH2469 pKa = 3.93 NWKK2472 pKa = 7.87 VTGMGIGMPMNQSMITLYY2490 pKa = 11.04 NNLMRR2495 pKa = 11.84 SKK2497 pKa = 10.25 KK2498 pKa = 9.9 EE2499 pKa = 3.74 CGGMYY2504 pKa = 10.34 AIADD2508 pKa = 3.39 AHH2510 pKa = 6.59 EE2511 pKa = 4.49 YY2512 pKa = 10.64 DD2513 pKa = 3.79 SRR2515 pKa = 11.84 KK2516 pKa = 10.33 APFTFEE2522 pKa = 4.08 VLAKK2526 pKa = 9.97 LAEE2529 pKa = 4.01 IGYY2532 pKa = 9.09 EE2533 pKa = 4.18 GKK2535 pKa = 9.2 PQASVLKK2542 pKa = 10.17 AKK2544 pKa = 10.63 YY2545 pKa = 9.68 DD2546 pKa = 3.71 ALQSSFIFQEE2556 pKa = 4.13 TMPNHH2561 pKa = 6.41 HH2562 pKa = 7.02 NSTSVIVPDD2571 pKa = 3.9 AAIASALMKK2580 pKa = 10.18 KK2581 pKa = 9.98 HH2582 pKa = 6.43 PDD2584 pKa = 3.11 KK2585 pKa = 11.1 FITAEE2590 pKa = 4.08 LLHH2593 pKa = 6.93 SVFPRR2598 pKa = 11.84 LSQTDD2603 pKa = 4.76 LYY2605 pKa = 10.91 NDD2607 pKa = 3.13 SHH2609 pKa = 7.11 PIHH2612 pKa = 7.05 RR2613 pKa = 11.84 LYY2615 pKa = 10.92 ADD2617 pKa = 3.48 KK2618 pKa = 11.17 VVLATRR2624 pKa = 11.84 EE2625 pKa = 4.13 DD2626 pKa = 4.13 EE2627 pKa = 4.52 LTFTDD2632 pKa = 3.07 STGRR2636 pKa = 11.84 MKK2638 pKa = 10.78 YY2639 pKa = 10.07 RR2640 pKa = 11.84 LLSPIFVRR2648 pKa = 11.84 AYY2650 pKa = 10.9 LNEE2653 pKa = 3.96 QPIGSPLPFQSFQNVDD2669 pKa = 3.57 KK2670 pKa = 10.45 MKK2672 pKa = 10.2 QWLIDD2677 pKa = 3.56 EE2678 pKa = 4.43 VQPNIHH2684 pKa = 6.7 LLYY2687 pKa = 10.91 NVAQKK2692 pKa = 10.82 NRR2694 pKa = 11.84 GGGTGEE2700 pKa = 5.15 NATSWDD2706 pKa = 3.72 NGWGYY2711 pKa = 10.9 KK2712 pKa = 9.82 AAFIATWVRR2721 pKa = 11.84 YY2722 pKa = 7.95 NEE2724 pKa = 4.0 KK2725 pKa = 10.52 LGISVKK2731 pKa = 10.47 PSDD2734 pKa = 4.99 FFAQGNILYY2743 pKa = 7.86 NTGDD2747 pKa = 3.56 DD2748 pKa = 3.9 SAIKK2752 pKa = 9.22 LTGVDD2757 pKa = 2.92 TATFNKK2763 pKa = 10.29 SLWLEE2768 pKa = 3.79 CALYY2772 pKa = 10.76 YY2773 pKa = 10.82 GLEE2776 pKa = 4.18 LDD2778 pKa = 5.87 FDD2780 pKa = 4.03 FTDD2783 pKa = 4.71 DD2784 pKa = 3.54 IKK2786 pKa = 11.18 EE2787 pKa = 3.96 VEE2789 pKa = 4.27 YY2790 pKa = 10.82 LGNAIRR2796 pKa = 11.84 RR2797 pKa = 11.84 PNTDD2801 pKa = 3.84 DD2802 pKa = 4.29 LVKK2805 pKa = 10.86 LKK2807 pKa = 10.4 AWQKK2811 pKa = 10.62 MMTNVQRR2818 pKa = 11.84 SRR2820 pKa = 11.84 KK2821 pKa = 9.21 EE2822 pKa = 4.15 EE2823 pKa = 3.77 ICPPPLPRR2831 pKa = 11.84 WLVYY2835 pKa = 10.3 HH2836 pKa = 6.54 KK2837 pKa = 10.61 EE2838 pKa = 3.72 RR2839 pKa = 11.84 DD2840 pKa = 3.48 SFIRR2844 pKa = 11.84 LSSRR2848 pKa = 11.84 RR2849 pKa = 11.84 YY2850 pKa = 8.86 YY2851 pKa = 10.52 QNQPGNLSFVHH2862 pKa = 6.55 HH2863 pKa = 6.63 NLAKK2867 pKa = 10.14 FAGTATIAVFNPTLWNVLANEE2888 pKa = 4.28 YY2889 pKa = 10.83 CSDD2892 pKa = 3.71 AEE2894 pKa = 4.38 RR2895 pKa = 11.84 LAKK2898 pKa = 10.11 HH2899 pKa = 5.51 YY2900 pKa = 9.41 NVPGFTATIKK2910 pKa = 10.42 KK2911 pKa = 10.11 DD2912 pKa = 3.56 QFGLDD2917 pKa = 3.91 YY2918 pKa = 10.79 IALSDD2923 pKa = 3.6 NSNARR2928 pKa = 11.84 RR2929 pKa = 11.84 GSDD2932 pKa = 3.22 LRR2934 pKa = 11.84 RR2935 pKa = 11.84 HH2936 pKa = 5.62 LRR2938 pKa = 11.84 AHH2940 pKa = 6.29 PGYY2943 pKa = 9.54 RR2944 pKa = 11.84 LSRR2947 pKa = 11.84 QEE2949 pKa = 3.81 EE2950 pKa = 4.86 FFTFLQGAKK2959 pKa = 9.9 FPSQAKK2965 pKa = 9.6 SIRR2968 pKa = 11.84 DD2969 pKa = 3.39 ALDD2972 pKa = 2.99 IKK2974 pKa = 10.4 TEE2976 pKa = 4.14 LPVIAQQLSFIQKK2989 pKa = 10.02 LEE2991 pKa = 4.19 KK2992 pKa = 10.48 KK2993 pKa = 10.27 SGNLLDD2999 pKa = 3.86 TTNLVVDD3006 pKa = 3.99 YY3007 pKa = 10.85 LSEE3010 pKa = 3.93 EE3011 pKa = 4.0 LAAIPRR3017 pKa = 11.84 YY3018 pKa = 8.91 IYY3020 pKa = 11.32 KK3021 pKa = 8.08 MTANILPATGEE3032 pKa = 4.0 PAFASANYY3040 pKa = 8.96 PVEE3043 pKa = 4.32 HH3044 pKa = 6.51 FVAACQKK3051 pKa = 10.29 PEE3053 pKa = 4.09 TEE3055 pKa = 4.43 GFMLGKK3061 pKa = 10.14 LARR3064 pKa = 11.84 SPWASVTNGSDD3075 pKa = 4.19 FYY3077 pKa = 11.61 RR3078 pKa = 11.84 HH3079 pKa = 5.76 LQDD3082 pKa = 3.86 TEE3084 pKa = 3.82 FATNHH3089 pKa = 5.64 EE3090 pKa = 4.59 SHH3092 pKa = 6.37 TKK3094 pKa = 8.5 EE3095 pKa = 4.03 AYY3097 pKa = 9.73 GSRR3100 pKa = 11.84 LVLALVLYY3108 pKa = 10.27 CLFYY3112 pKa = 10.74 FLEE3115 pKa = 5.57 GYY3117 pKa = 9.02 FVRR3120 pKa = 11.84 IPIFGTFIRR3129 pKa = 11.84 IFYY3132 pKa = 10.27 SIMIDD3137 pKa = 3.45 VPKK3140 pKa = 10.72 VYY3142 pKa = 10.41 GVLSCLYY3149 pKa = 7.69 WHH3151 pKa = 6.92 YY3152 pKa = 11.4 YY3153 pKa = 9.19 GDD3155 pKa = 3.61 NSPIVSALMPKK3166 pKa = 10.41 DD3167 pKa = 2.89 IFIWGKK3173 pKa = 9.71 RR3174 pKa = 11.84 FAVFIAANLPMFLFDD3189 pKa = 4.04 YY3190 pKa = 9.64 PISPFYY3196 pKa = 10.24 YY3197 pKa = 10.12 LYY3199 pKa = 10.44 YY3200 pKa = 10.05 ALSFIVVPIEE3210 pKa = 3.98 TLSMLIVSGKK3220 pKa = 7.68 QQSEE3224 pKa = 4.47 HH3225 pKa = 6.82 PGSKK3229 pKa = 9.38 PHH3231 pKa = 7.01 AAPFDD3236 pKa = 3.96 NPWDD3240 pKa = 3.56 NEE3242 pKa = 3.88 VRR3244 pKa = 11.84 SEE3246 pKa = 3.94 EE3247 pKa = 4.3 GRR3249 pKa = 11.84 FQVQMRR3255 pKa = 11.84 AKK3257 pKa = 8.79 TDD3259 pKa = 3.59 LVLPPVNASSQAIVVKK3275 pKa = 10.26 DD3276 pKa = 3.6 VPRR3279 pKa = 11.84 PFVVKK3284 pKa = 10.42 SAVGSGKK3291 pKa = 10.52 SSLFPYY3297 pKa = 10.78 ALLNNAKK3304 pKa = 9.86 WIDD3307 pKa = 3.61 NFKK3310 pKa = 11.1 DD3311 pKa = 3.39 LNTPTGGRR3319 pKa = 11.84 VVLSLPRR3326 pKa = 11.84 TILRR3330 pKa = 11.84 DD3331 pKa = 3.19 KK3332 pKa = 10.31 WSSPLEE3338 pKa = 4.15 NSRR3341 pKa = 11.84 QPYY3344 pKa = 9.59 QRR3346 pKa = 11.84 LQRR3349 pKa = 11.84 GTVLDD3354 pKa = 4.48 PKK3356 pKa = 10.98 AKK3358 pKa = 10.13 ILIGTDD3364 pKa = 2.87 GHH3366 pKa = 6.65 LLNRR3370 pKa = 11.84 LKK3372 pKa = 10.88 SGEE3375 pKa = 4.1 LTEE3378 pKa = 4.37 KK3379 pKa = 10.64 DD3380 pKa = 3.18 IYY3382 pKa = 11.33 LLDD3385 pKa = 4.19 EE3386 pKa = 4.08 FHH3388 pKa = 7.06 EE3389 pKa = 4.59 LNGQKK3394 pKa = 10.03 VALFQEE3400 pKa = 4.22 LLEE3403 pKa = 4.39 RR3404 pKa = 11.84 KK3405 pKa = 9.12 CRR3407 pKa = 11.84 VMLPSATPKK3416 pKa = 9.93 PVPGINMGIMEE3427 pKa = 4.63 AAIPRR3432 pKa = 11.84 RR3433 pKa = 11.84 FAPDD3437 pKa = 2.82 IWPISDD3443 pKa = 4.14 SISPADD3449 pKa = 3.9 ALRR3452 pKa = 11.84 QFGPNFVTQWPLTGPRR3468 pKa = 11.84 DD3469 pKa = 3.62 AEE3471 pKa = 4.3 SFKK3474 pKa = 11.4 DD3475 pKa = 3.71 RR3476 pKa = 11.84 VLIKK3480 pKa = 9.57 CTHH3483 pKa = 5.39 INGRR3487 pKa = 11.84 NGVNEE3492 pKa = 4.0 TMEE3495 pKa = 4.21 ILQYY3499 pKa = 10.56 DD3500 pKa = 3.47 QWNCYY3505 pKa = 10.5 ALTSEE3510 pKa = 4.72 SARR3513 pKa = 11.84 DD3514 pKa = 4.19 PIPDD3518 pKa = 3.48 SAQVVIATDD3527 pKa = 4.01 VINTGISLPGFKK3539 pKa = 10.69 LLVYY3543 pKa = 9.57 DD3544 pKa = 4.52 GKK3546 pKa = 9.58 MHH3548 pKa = 6.7 SVHH3551 pKa = 6.81 QGEE3554 pKa = 5.03 HH3555 pKa = 4.92 QLTWTDD3561 pKa = 3.89 PDD3563 pKa = 3.85 TKK3565 pKa = 9.54 HH3566 pKa = 6.87 QGMARR3571 pKa = 11.84 VGRR3574 pKa = 11.84 YY3575 pKa = 9.6 GPGDD3579 pKa = 3.51 VVLCPVSAGTGATPQVYY3596 pKa = 8.43 PAMSYY3601 pKa = 9.96 LAWSMNAQAHH3611 pKa = 6.61 DD3612 pKa = 4.39 LPQLCSFNDD3621 pKa = 3.75 YY3622 pKa = 11.6 NEE3624 pKa = 4.36 GTSLQSKK3631 pKa = 9.96 YY3632 pKa = 10.69 EE3633 pKa = 4.22 STNLTPYY3640 pKa = 10.31 LAVSKK3645 pKa = 9.33 EE3646 pKa = 4.1 VPTFMRR3652 pKa = 11.84 DD3653 pKa = 3.34 AISVYY3658 pKa = 10.26 HH3659 pKa = 7.12 AIANMGCRR3667 pKa = 11.84 QSEE3670 pKa = 3.81 IRR3672 pKa = 11.84 GVYY3675 pKa = 10.23 NKK3677 pKa = 10.22 IIMNKK3682 pKa = 9.41 PVDD3685 pKa = 3.63 EE3686 pKa = 4.74 SYY3688 pKa = 11.63 EE3689 pKa = 3.87 LVQRR3693 pKa = 11.84 FFAPKK3698 pKa = 9.62 SRR3700 pKa = 11.84 NAMPYY3705 pKa = 8.17 EE3706 pKa = 4.05 AVVMTMAQHH3715 pKa = 6.33 PVLYY3719 pKa = 9.05 MCRR3722 pKa = 11.84 NLTPKK3727 pKa = 8.9 TQVPVATILDD3737 pKa = 4.3 LEE3739 pKa = 4.94 LSPSTPRR3746 pKa = 11.84 LYY3748 pKa = 10.54 DD3749 pKa = 3.89 AYY3751 pKa = 10.84 CCQTVNPLVPYY3762 pKa = 10.08 KK3763 pKa = 10.85 ARR3765 pKa = 11.84 LRR3767 pKa = 11.84 PLDD3770 pKa = 3.7 EE3771 pKa = 4.47 TDD3773 pKa = 3.98 SKK3775 pKa = 11.43 INNNFIIGAEE3785 pKa = 4.07 SKK3787 pKa = 10.36 PIQVYY3792 pKa = 7.27 QQIVDD3797 pKa = 2.87 IHH3799 pKa = 6.23 QSHH3802 pKa = 5.74 TRR3804 pKa = 11.84 MARR3807 pKa = 11.84 EE3808 pKa = 3.83 ALTDD3812 pKa = 3.48 ALEE3815 pKa = 4.2 AVKK3818 pKa = 10.43 DD3819 pKa = 3.78 LRR3821 pKa = 11.84 IKK3823 pKa = 10.64 KK3824 pKa = 9.58 DD3825 pKa = 3.14 WTVEE3829 pKa = 3.92 TLRR3832 pKa = 11.84 NGLRR3836 pKa = 11.84 KK3837 pKa = 10.15 CIATHH3842 pKa = 5.45 INKK3845 pKa = 9.69 LNRR3848 pKa = 11.84 EE3849 pKa = 3.83 IDD3851 pKa = 3.92 TNEE3854 pKa = 3.89 HH3855 pKa = 6.46 KK3856 pKa = 10.9 SNKK3859 pKa = 9.83 LKK3861 pKa = 11.01 FNLTEE3866 pKa = 4.02 SSRR3869 pKa = 11.84 IDD3871 pKa = 3.14 PTLAYY3876 pKa = 8.4 TIKK3879 pKa = 10.55 GGQQFIHH3886 pKa = 5.23 NHH3888 pKa = 5.84 KK3889 pKa = 9.76 LNCPMCSKK3897 pKa = 8.31 TQPHH3901 pKa = 5.11 THH3903 pKa = 5.46 VGYY3906 pKa = 11.0 NGMAEE3911 pKa = 3.92 TSYY3914 pKa = 11.17 DD3915 pKa = 3.98 YY3916 pKa = 10.87 RR3917 pKa = 11.84 DD3918 pKa = 3.07 SWIDD3922 pKa = 3.5 SLVEE3926 pKa = 3.7 TDD3928 pKa = 5.13 DD3929 pKa = 5.62 FILFHH3934 pKa = 7.49 HH3935 pKa = 7.13 GDD3937 pKa = 3.56 GLSEE3941 pKa = 4.06 NKK3943 pKa = 10.25 ASEE3946 pKa = 4.27 EE3947 pKa = 3.97 NRR3949 pKa = 11.84 KK3950 pKa = 9.38 SLHH3953 pKa = 5.24 STSGNKK3959 pKa = 9.4 RR3960 pKa = 11.84 PKK3962 pKa = 10.39 KK3963 pKa = 9.92 IGTLHH3968 pKa = 6.97 PPTT3971 pKa = 4.5
Molecular weight: 450.53 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 7.284
IPC2_protein 7.702
IPC_protein 7.454
Toseland 7.234
ProMoST 8.083
Dawson 8.214
Bjellqvist 8.565
Wikipedia 8.141
Rodwell 8.244
Grimsley 7.351
Solomon 8.229
Lehninger 8.229
Nozaki 8.668
DTASelect 8.302
Thurlkill 8.361
EMBOSS 8.404
Sillero 8.653
Patrickios 4.215
IPC_peptide 8.214
IPC2_peptide 7.483
IPC2.peptide.svr19 7.626
Protein with the highest isoelectric point:
>tr|A0A2Z5WQ87|A0A2Z5WQ87_9VIRU RNA-directed RNA polymerase OS=Rosellinia necatrix hypovirus 1 OX=2032989 GN=RdRP PE=4 SV=1
MM1 pKa = 7.72 NPGQKK6 pKa = 9.63 RR7 pKa = 11.84 GSRR10 pKa = 11.84 PPQTPNYY17 pKa = 8.57 SRR19 pKa = 11.84 SSSRR23 pKa = 11.84 STTSSVGLTSEE34 pKa = 4.04 PQMLLDD40 pKa = 4.34 RR41 pKa = 11.84 FSAQLAEE48 pKa = 4.39 QEE50 pKa = 4.21 RR51 pKa = 11.84 HH52 pKa = 5.71 LADD55 pKa = 3.59 PTSRR59 pKa = 11.84 PDD61 pKa = 3.11 WPICCFCPSKK71 pKa = 11.0 LSVDD75 pKa = 3.76 DD76 pKa = 3.64 VTGKK80 pKa = 10.15 IVICRR85 pKa = 11.84 ACVNSHH91 pKa = 7.02 DD92 pKa = 4.25 EE93 pKa = 3.94 IFRR96 pKa = 11.84 QLEE99 pKa = 4.31 AQCSPVLEE107 pKa = 4.59 APSPRR112 pKa = 11.84 TVLAPIEE119 pKa = 4.34 EE120 pKa = 4.37 EE121 pKa = 4.19 PEE123 pKa = 4.07 PVVSEE128 pKa = 4.16 SRR130 pKa = 11.84 VGIVIPVVEE139 pKa = 4.97 DD140 pKa = 3.54 VPAPVVEE147 pKa = 4.41 PLPFLTEE154 pKa = 3.67 YY155 pKa = 10.78 AAPRR159 pKa = 11.84 WEE161 pKa = 4.14 QEE163 pKa = 3.9 SLLVGGSVSRR173 pKa = 11.84 PVINFPKK180 pKa = 9.56 VHH182 pKa = 6.36 SPSVAEE188 pKa = 3.97 TSRR191 pKa = 11.84 APEE194 pKa = 4.08 LVFTAPKK201 pKa = 8.15 TTDD204 pKa = 2.96 NVTITLVVTVPGGDD218 pKa = 2.99 VDD220 pKa = 3.72 KK221 pKa = 10.51 WLKK224 pKa = 10.55 GPSRR228 pKa = 11.84 MSNLDD233 pKa = 3.34 WILRR237 pKa = 11.84 EE238 pKa = 3.42 HH239 pKa = 7.15 DD240 pKa = 3.2 RR241 pKa = 11.84 RR242 pKa = 11.84 IEE244 pKa = 3.9 RR245 pKa = 11.84 EE246 pKa = 3.72 NRR248 pKa = 11.84 SLIRR252 pKa = 11.84 ASLYY256 pKa = 10.16 KK257 pKa = 10.35 VRR259 pKa = 11.84 SKK261 pKa = 11.1 AYY263 pKa = 8.17 WADD266 pKa = 3.44 LVSSMKK272 pKa = 9.9 EE273 pKa = 3.43 RR274 pKa = 11.84 RR275 pKa = 11.84 AVQQKK280 pKa = 10.34 AYY282 pKa = 8.92 RR283 pKa = 11.84 TARR286 pKa = 11.84 DD287 pKa = 3.32 QSRR290 pKa = 11.84 TAISAPLVLANKK302 pKa = 8.54 FSCLTEE308 pKa = 4.0 DD309 pKa = 3.39 EE310 pKa = 5.47 RR311 pKa = 11.84 EE312 pKa = 4.11 DD313 pKa = 4.29 FYY315 pKa = 11.57 HH316 pKa = 7.17 GIIPAVRR323 pKa = 11.84 PSLPTRR329 pKa = 11.84 SWPKK333 pKa = 9.91 RR334 pKa = 11.84 KK335 pKa = 9.38 RR336 pKa = 11.84 APIPAEE342 pKa = 4.12 KK343 pKa = 10.01 KK344 pKa = 9.93 KK345 pKa = 10.98 SPPAPFEE352 pKa = 4.24 RR353 pKa = 11.84 DD354 pKa = 3.19 PLLLEE359 pKa = 4.53 RR360 pKa = 11.84 LHH362 pKa = 7.0 KK363 pKa = 10.75 LLEE366 pKa = 4.28 HH367 pKa = 7.27 LLNQRR372 pKa = 11.84 RR373 pKa = 11.84 KK374 pKa = 8.98 KK375 pKa = 9.18 IHH377 pKa = 6.38 RR378 pKa = 11.84 KK379 pKa = 6.58 VTVSRR384 pKa = 11.84 SSCEE388 pKa = 3.91 RR389 pKa = 11.84 MSCPSTGTLLSTNTVKK405 pKa = 10.68 RR406 pKa = 11.84 AKK408 pKa = 10.04 ADD410 pKa = 3.43 NVGLVGIEE418 pKa = 4.24 SNPGPEE424 pKa = 3.92 YY425 pKa = 10.81 SGPLDD430 pKa = 3.8 ANFSISLTATLPCLRR445 pKa = 11.84 VNYY448 pKa = 10.11 SQLQAFDD455 pKa = 4.07 DD456 pKa = 4.33 AEE458 pKa = 4.15 MAEE461 pKa = 4.44 LMRR464 pKa = 11.84 CGYY467 pKa = 8.32 ATKK470 pKa = 10.66 SPWNEE475 pKa = 3.52 VSILCSWIXKK485 pKa = 7.89 GQSVLGWVFSDD496 pKa = 3.82 RR497 pKa = 11.84 SHH499 pKa = 6.72 RR500 pKa = 11.84 AAAGSHH506 pKa = 4.76 KK507 pKa = 10.3 VAWYY511 pKa = 9.97 QPTLHH516 pKa = 7.79 VYY518 pKa = 7.6 MQQGYY523 pKa = 6.74 TGKK526 pKa = 10.49 LLAYY530 pKa = 10.12 RR531 pKa = 11.84 FNCYY535 pKa = 7.49 EE536 pKa = 3.76 WSKK539 pKa = 10.5 QASTAQDD546 pKa = 3.29 PKK548 pKa = 10.85 AIPGLEE554 pKa = 3.77 QSVAEE559 pKa = 5.06 DD560 pKa = 3.7 FTDD563 pKa = 4.66 GNWSTWFQLLQKK575 pKa = 10.18 YY576 pKa = 9.3 QDD578 pKa = 3.52 SLRR581 pKa = 11.84 ACKK584 pKa = 10.34 KK585 pKa = 10.25 EE586 pKa = 3.39 ISEE589 pKa = 4.19 LKK591 pKa = 10.32 KK592 pKa = 10.37 PEE594 pKa = 4.07 GARR597 pKa = 11.84 KK598 pKa = 8.38 HH599 pKa = 6.37 CKK601 pKa = 8.24 HH602 pKa = 6.3 HH603 pKa = 6.93 VYY605 pKa = 11.08 ADD607 pKa = 3.98 DD608 pKa = 4.12 FTLLPQTQLEE618 pKa = 4.32 EE619 pKa = 4.11 FRR621 pKa = 11.84 NLSLNRR627 pKa = 11.84 TDD629 pKa = 6.69 FIDD632 pKa = 3.06 IMNRR636 pKa = 11.84 LTSPSVYY643 pKa = 8.87 TSPYY647 pKa = 10.08 IYY649 pKa = 9.59 DD650 pKa = 4.3 TIANLDD656 pKa = 3.65 NQIGNNLTRR665 pKa = 11.84 YY666 pKa = 9.38 RR667 pKa = 11.84 SHH669 pKa = 8.51 SEE671 pKa = 3.29 IKK673 pKa = 9.73 IGNRR677 pKa = 11.84 IHH679 pKa = 6.57 SCEE682 pKa = 4.28 DD683 pKa = 3.14 APATTITNGLDD694 pKa = 3.44 FEE696 pKa = 4.91 SGSDD700 pKa = 4.43 RR701 pKa = 11.84 NDD703 pKa = 3.01 QCSTDD708 pKa = 4.1 GIVTRR713 pKa = 11.84 LRR715 pKa = 11.84 HH716 pKa = 6.01 DD717 pKa = 3.61 AQDD720 pKa = 3.33 PXVRR724 pKa = 11.84 DD725 pKa = 3.65 LSXEE729 pKa = 4.08 GLHH732 pKa = 6.52 GVNFDD737 pKa = 4.05 LSVSPRR743 pKa = 11.84 SLPRR747 pKa = 11.84 GTLEE751 pKa = 4.0 FLASINYY758 pKa = 9.42 DD759 pKa = 3.33 HH760 pKa = 6.97 VPPRR764 pKa = 11.84 DD765 pKa = 3.21 IVLTANRR772 pKa = 11.84 MWLNDD777 pKa = 3.97 LPGSPYY783 pKa = 10.02 IIEE786 pKa = 4.4 LRR788 pKa = 11.84 STTDD792 pKa = 2.72 ASHH795 pKa = 6.64 IVYY798 pKa = 10.06 DD799 pKa = 4.38 RR800 pKa = 11.84 KK801 pKa = 10.62 RR802 pKa = 11.84 KK803 pKa = 7.64 TKK805 pKa = 9.95 MIIYY809 pKa = 8.9 LQGVEE814 pKa = 4.59 GKK816 pKa = 9.47 QLQLLRR822 pKa = 11.84 FEE824 pKa = 4.94 PLFHH828 pKa = 6.99 LKK830 pKa = 8.28 HH831 pKa = 5.24 TARR834 pKa = 11.84 ALVLNGGRR842 pKa = 11.84 MGSKK846 pKa = 8.83 WFAPYY851 pKa = 9.62 RR852 pKa = 11.84 QEE854 pKa = 4.28 YY855 pKa = 7.14 PTPQYY860 pKa = 9.84 EE861 pKa = 4.33 LPYY864 pKa = 9.69 VYY866 pKa = 9.61 PVSAGCCWIKK876 pKa = 10.5 RR877 pKa = 11.84 ADD879 pKa = 3.85 MEE881 pKa = 4.32 LHH883 pKa = 6.05 KK884 pKa = 10.86 VDD886 pKa = 3.24 WYY888 pKa = 11.03 KK889 pKa = 11.3 AFSGWSGVYY898 pKa = 10.34 GVDD901 pKa = 2.98 EE902 pKa = 4.44 NMLARR907 pKa = 11.84 YY908 pKa = 8.7 EE909 pKa = 4.12 GFMFLRR915 pKa = 11.84 GRR917 pKa = 11.84 SFSTSTHH924 pKa = 6.39 AGTNVPVTTHH934 pKa = 7.14 FIDD937 pKa = 4.81 ADD939 pKa = 3.62 THH941 pKa = 4.12 QTYY944 pKa = 10.02 FSAYY948 pKa = 6.36 WWSAKK953 pKa = 8.75 IARR956 pKa = 11.84 RR957 pKa = 11.84 INSLTFSHH965 pKa = 5.99 SQHH968 pKa = 6.15 WDD970 pKa = 3.35 DD971 pKa = 5.66 VKK973 pKa = 11.33 LLLPSQTPYY982 pKa = 11.08 EE983 pKa = 4.61 HH984 pKa = 7.54 DD985 pKa = 4.4 LDD987 pKa = 4.15 PSKK990 pKa = 11.16 LFGQLPGRR998 pKa = 11.84 KK999 pKa = 8.73 VPYY1002 pKa = 10.18 DD1003 pKa = 3.84 RR1004 pKa = 11.84 LPTLAILDD1012 pKa = 4.49 DD1013 pKa = 4.29 GGKK1016 pKa = 7.91 TLLCNAYY1023 pKa = 10.41 DD1024 pKa = 3.64 RR1025 pKa = 11.84 FVTPTHH1031 pKa = 6.1 SKK1033 pKa = 9.06 RR1034 pKa = 11.84 VIYY1037 pKa = 9.81 YY1038 pKa = 8.18 GHH1040 pKa = 7.41 AALTPAMVDD1049 pKa = 3.84 FLLTRR1054 pKa = 11.84 DD1055 pKa = 3.65 IILVVAEE1062 pKa = 4.54 HH1063 pKa = 6.7 WCASFDD1069 pKa = 3.56 TSRR1072 pKa = 11.84 FDD1074 pKa = 3.97 IKK1076 pKa = 10.08 VQRR1079 pKa = 11.84 PINARR1084 pKa = 11.84 RR1085 pKa = 11.84 KK1086 pKa = 9.23 VSYY1089 pKa = 10.18 HH1090 pKa = 4.95 SCEE1093 pKa = 4.17 NQTSRR1098 pKa = 11.84 SPLSPNDD1105 pKa = 3.4 FFNEE1109 pKa = 4.17 CVTFANTHH1117 pKa = 6.5 LEE1119 pKa = 4.19 TKK1121 pKa = 9.84 IRR1123 pKa = 11.84 RR1124 pKa = 11.84 DD1125 pKa = 3.14 PRR1127 pKa = 11.84 LEE1129 pKa = 3.85 VSEE1132 pKa = 4.65 ANPGAKK1138 pKa = 9.55 LVFGYY1143 pKa = 10.8 DD1144 pKa = 3.63 VFPLGYY1150 pKa = 10.5 AKK1152 pKa = 10.48 DD1153 pKa = 3.42 SRR1155 pKa = 11.84 FRR1157 pKa = 11.84 VTLEE1161 pKa = 3.82 NGCKK1165 pKa = 9.67 VFKK1168 pKa = 10.8 ANQPDD1173 pKa = 3.74 ISTLRR1178 pKa = 11.84 SMSRR1182 pKa = 11.84 VWADD1186 pKa = 3.02 PATFYY1191 pKa = 11.63 AEE1193 pKa = 4.31 LPQFIKK1199 pKa = 10.47 PVAPEE1204 pKa = 3.87 PVLNRR1209 pKa = 11.84 ATINWYY1215 pKa = 10.2 GYY1217 pKa = 9.3 VYY1219 pKa = 10.6 SIFSLLRR1226 pKa = 11.84 GKK1228 pKa = 10.33 AIYY1231 pKa = 8.96 PIIFVALMPAVLARR1245 pKa = 11.84 RR1246 pKa = 11.84 QIVSAISTQTVNASRR1261 pKa = 11.84 PVWNAYY1267 pKa = 7.56 QASGNTYY1274 pKa = 7.79 QTLNINHH1281 pKa = 7.63 IYY1283 pKa = 7.93 TQPLQATGNFSKK1295 pKa = 10.4 FIWSLGIWVRR1305 pKa = 11.84 IARR1308 pKa = 11.84 QFGNVFYY1315 pKa = 11.21 GLLDD1319 pKa = 3.55 TAHH1322 pKa = 7.42 EE1323 pKa = 4.12 IGIVLVTWLAAVIFVFGIWFHH1344 pKa = 5.54 LWGYY1348 pKa = 9.38 KK1349 pKa = 9.02 YY1350 pKa = 10.42 QGIVPTILDD1359 pKa = 4.06 DD1360 pKa = 3.85 NALFSISDD1368 pKa = 3.41 NSTPVTDD1375 pKa = 4.12 EE1376 pKa = 4.62 DD1377 pKa = 4.59 LSEE1380 pKa = 4.23 ALCIVTYY1387 pKa = 7.26 GTRR1390 pKa = 11.84 GDD1392 pKa = 5.05 HH1393 pKa = 7.61 IPMQYY1398 pKa = 10.38 FGRR1401 pKa = 11.84 LAALYY1406 pKa = 9.6 GVRR1409 pKa = 11.84 THH1411 pKa = 6.98 NYY1413 pKa = 8.06 QAHH1416 pKa = 6.42 LGDD1419 pKa = 4.18 NKK1421 pKa = 10.2 TLEE1424 pKa = 4.07 QLRR1427 pKa = 11.84 RR1428 pKa = 11.84 ADD1430 pKa = 3.61 FTGLRR1435 pKa = 11.84 LRR1437 pKa = 11.84 YY1438 pKa = 9.38 LEE1440 pKa = 5.43 LMTTSLLPYY1449 pKa = 8.61 KK1450 pKa = 10.4 QIMQPFVHH1458 pKa = 6.86 LGGKK1462 pKa = 6.33 VTSYY1466 pKa = 10.19 TLSPSEE1472 pKa = 4.7 AFVHH1476 pKa = 5.98 PLNFGGNPTLFSKK1489 pKa = 10.57 FASFANRR1496 pKa = 11.84 FFNPDD1501 pKa = 3.24 LRR1503 pKa = 11.84 VGALKK1508 pKa = 10.62 EE1509 pKa = 4.35 SVLPRR1514 pKa = 11.84 SPDD1517 pKa = 3.15 GKK1519 pKa = 10.61 KK1520 pKa = 10.23 LLRR1523 pKa = 11.84 MLPAVTAGPEE1533 pKa = 4.14 AYY1535 pKa = 8.61 THH1537 pKa = 6.2 GSEE1540 pKa = 4.29 DD1541 pKa = 3.66 ASVIPYY1547 pKa = 9.28 GVKK1550 pKa = 10.03 LRR1552 pKa = 11.84 CPKK1555 pKa = 10.51 LEE1557 pKa = 4.52 SGDD1560 pKa = 3.69 HH1561 pKa = 5.38 QIVMRR1566 pKa = 11.84 KK1567 pKa = 8.67 YY1568 pKa = 9.59 SGIYY1572 pKa = 8.44 SHH1574 pKa = 7.07 AGAGTLQTILMSGIPVEE1591 pKa = 4.39 RR1592 pKa = 11.84 RR1593 pKa = 11.84 HH1594 pKa = 6.23 ICDD1597 pKa = 3.08 INIDD1601 pKa = 3.63 RR1602 pKa = 11.84 WYY1604 pKa = 9.41 HH1605 pKa = 5.94 TIPTLNDD1612 pKa = 2.94 VTEE1615 pKa = 4.36 RR1616 pKa = 11.84 SPYY1619 pKa = 10.25 VFLGYY1624 pKa = 10.48 LIVKK1628 pKa = 10.02 GFDD1631 pKa = 3.43 LKK1633 pKa = 10.92 ISLWDD1638 pKa = 3.27 KK1639 pKa = 10.73 FLAIGIWLFTTCTAKK1654 pKa = 10.87 SFVDD1658 pKa = 4.81 TIAWGYY1664 pKa = 9.7 RR1665 pKa = 11.84 YY1666 pKa = 10.09 YY1667 pKa = 11.34 AVFYY1671 pKa = 9.32 GFRR1674 pKa = 11.84 SILHH1678 pKa = 4.8 QVILVILTFPSIAHH1692 pKa = 6.18 FFGVTWLKK1700 pKa = 11.12 LPLCAIASALIDD1712 pKa = 4.19 APILTQMGSIWTLLYY1727 pKa = 9.42 MAYY1730 pKa = 9.98 QYY1732 pKa = 11.67 AQFVPKK1738 pKa = 10.07 VISEE1742 pKa = 3.93 ISSWLDD1748 pKa = 3.17 TRR1750 pKa = 11.84 SEE1752 pKa = 4.05 LVMTSNEE1759 pKa = 4.15 SFPAPFGHH1767 pKa = 7.13 WYY1769 pKa = 10.38 VVDD1772 pKa = 3.44 HH1773 pKa = 6.79 RR1774 pKa = 11.84 SGRR1777 pKa = 11.84 RR1778 pKa = 11.84 YY1779 pKa = 9.49 EE1780 pKa = 4.26 GSFSGSKK1787 pKa = 9.82 GWHH1790 pKa = 5.3 QKK1792 pKa = 10.39 FGWIAHH1798 pKa = 4.94 TRR1800 pKa = 11.84 VFNNTDD1806 pKa = 3.19 MEE1808 pKa = 4.54 DD1809 pKa = 2.9 RR1810 pKa = 11.84 GYY1812 pKa = 11.18 YY1813 pKa = 7.1 QTLYY1817 pKa = 10.67 MFITALAFIVATACLCCFSHH1837 pKa = 6.87 PLISFSMVLVSIFLFAFVICEE1858 pKa = 3.88 PLYY1861 pKa = 10.82 QYY1863 pKa = 11.04 AQYY1866 pKa = 11.47 GSTQKK1871 pKa = 10.2 IKK1873 pKa = 10.63 KK1874 pKa = 8.73 EE1875 pKa = 3.75 YY1876 pKa = 10.07 RR1877 pKa = 11.84 IPLPFTSNTVEE1888 pKa = 4.01 RR1889 pKa = 11.84 MAAAYY1894 pKa = 9.45 ARR1896 pKa = 11.84 NEE1898 pKa = 4.17 DD1899 pKa = 3.44 LGGYY1903 pKa = 9.85 HH1904 pKa = 7.33 PFFNCQSLVIPLVYY1918 pKa = 10.57 DD1919 pKa = 3.33 STLFCAAFCTLVFLFTLTVLIPGWAAAVMKK1949 pKa = 9.79 PLVKK1953 pKa = 10.24 RR1954 pKa = 11.84 LSIRR1958 pKa = 11.84 IWDD1961 pKa = 3.69 VSLEE1965 pKa = 4.75 DD1966 pKa = 3.67 ILEE1969 pKa = 4.77 DD1970 pKa = 3.35 IQRR1973 pKa = 11.84 STNFAAAPPVKK1984 pKa = 9.77 TEE1986 pKa = 4.4 NVPSDD1991 pKa = 3.75 PSPTPFKK1998 pKa = 10.87 EE1999 pKa = 3.45 RR2000 pKa = 11.84 VQGYY2004 pKa = 8.7 RR2005 pKa = 11.84 EE2006 pKa = 3.86 AGIPEE2011 pKa = 4.09 VEE2013 pKa = 4.52 LPQDD2017 pKa = 3.4 EE2018 pKa = 4.31 QAEE2021 pKa = 4.44 LKK2023 pKa = 10.95 LIDD2026 pKa = 3.09 YY2027 pKa = 7.4 WTRR2030 pKa = 11.84 KK2031 pKa = 6.98 FHH2033 pKa = 6.54 EE2034 pKa = 4.74 PLDD2037 pKa = 3.57 IFEE2040 pKa = 4.51 QVQTLYY2046 pKa = 10.66 KK2047 pKa = 10.73 LSMDD2051 pKa = 3.84 PTQSHH2056 pKa = 7.06 PLSEE2060 pKa = 5.32 AEE2062 pKa = 4.15 AEE2064 pKa = 4.49 HH2065 pKa = 5.93 VRR2067 pKa = 11.84 AMTLAKK2073 pKa = 10.35 YY2074 pKa = 10.21 LEE2076 pKa = 4.2 HH2077 pKa = 6.69 HH2078 pKa = 6.22 VSEE2081 pKa = 4.82 EE2082 pKa = 4.03 EE2083 pKa = 4.24 VEE2085 pKa = 4.35 LEE2087 pKa = 3.83 ARR2089 pKa = 11.84 MPGATSIIHH2098 pKa = 6.31 SEE2100 pKa = 4.12 MPPSQNDD2107 pKa = 3.47 PTSPNAHH2114 pKa = 6.47 LWAKK2118 pKa = 10.11 FVGKK2122 pKa = 10.17 LDD2124 pKa = 3.69 EE2125 pKa = 5.43 FLSIWSGEE2133 pKa = 4.07 KK2134 pKa = 10.02 FVSDD2138 pKa = 4.08 IISWLRR2144 pKa = 11.84 NQRR2147 pKa = 11.84 FKK2149 pKa = 11.33 HH2150 pKa = 5.74 LGDD2153 pKa = 3.3 LAFRR2157 pKa = 11.84 VYY2159 pKa = 10.78 HH2160 pKa = 6.09 LLCFIGRR2167 pKa = 11.84 IVYY2170 pKa = 7.53 TTSFNAWRR2178 pKa = 11.84 VLNLGMTCFLTCIFPVEE2195 pKa = 3.78 EE2196 pKa = 4.05 AKK2198 pKa = 10.55 RR2199 pKa = 11.84 LKK2201 pKa = 10.47 SAWAFAGLTKK2211 pKa = 10.48 TPFLSTKK2218 pKa = 9.94 RR2219 pKa = 11.84 RR2220 pKa = 11.84 FVEE2223 pKa = 4.54 NIAWSTKK2230 pKa = 6.97 EE2231 pKa = 3.62 EE2232 pKa = 4.02 RR2233 pKa = 11.84 GDD2235 pKa = 3.6 FLEE2238 pKa = 5.15 SFTSMVDD2245 pKa = 3.71 EE2246 pKa = 4.7 INHH2249 pKa = 4.89 YY2250 pKa = 7.63 CQRR2253 pKa = 11.84 HH2254 pKa = 4.78 GAPGIEE2260 pKa = 4.41 LHH2262 pKa = 5.4 PQYY2265 pKa = 10.94 RR2266 pKa = 11.84 KK2267 pKa = 10.34 VNVGRR2272 pKa = 11.84 PVLDD2276 pKa = 4.47 DD2277 pKa = 3.85 EE2278 pKa = 4.59 QATLLGLNKK2287 pKa = 9.99 DD2288 pKa = 4.02 AYY2290 pKa = 10.01 VTDD2293 pKa = 3.55 QRR2295 pKa = 11.84 STDD2298 pKa = 3.74 FTRR2301 pKa = 11.84 SLRR2304 pKa = 11.84 EE2305 pKa = 3.45 KK2306 pKa = 9.22 GTPISADD2313 pKa = 3.17 TVYY2316 pKa = 9.98 LTDD2319 pKa = 4.42 KK2320 pKa = 10.8 IEE2322 pKa = 4.0 YY2323 pKa = 7.95 VQQSVRR2329 pKa = 11.84 RR2330 pKa = 11.84 YY2331 pKa = 7.6 IPRR2334 pKa = 11.84 YY2335 pKa = 9.18 EE2336 pKa = 4.81 PISHH2340 pKa = 6.75 EE2341 pKa = 4.57 DD2342 pKa = 3.0 KK2343 pKa = 11.21 LLAHH2347 pKa = 7.27 EE2348 pKa = 4.64 IAAEE2352 pKa = 4.1 FGSRR2356 pKa = 11.84 FPDD2359 pKa = 3.25 SFKK2362 pKa = 10.74 DD2363 pKa = 3.55 AKK2365 pKa = 10.09 TLTPRR2370 pKa = 11.84 QVQAYY2375 pKa = 8.61 YY2376 pKa = 9.61 KK2377 pKa = 10.37 AKK2379 pKa = 9.82 YY2380 pKa = 9.9 APGSPWISIYY2390 pKa = 10.52 KK2391 pKa = 9.75 SRR2393 pKa = 11.84 QALEE2397 pKa = 3.94 DD2398 pKa = 3.45 AGITKK2403 pKa = 10.6 ALFEE2407 pKa = 4.27 MVEE2410 pKa = 4.21 DD2411 pKa = 4.16 RR2412 pKa = 11.84 LASGKK2417 pKa = 10.33 YY2418 pKa = 8.77 PDD2420 pKa = 4.4 MYY2422 pKa = 10.68 HH2423 pKa = 6.42 KK2424 pKa = 10.83 AFVKK2428 pKa = 10.42 SQVVNLDD2435 pKa = 3.2 KK2436 pKa = 11.23 VINGNKK2442 pKa = 9.16 NVRR2445 pKa = 11.84 TVVAQEE2451 pKa = 3.67 LLTYY2455 pKa = 9.6 FMNMCMEE2462 pKa = 4.61 LEE2464 pKa = 4.13 RR2465 pKa = 11.84 NHH2467 pKa = 5.27 RR2468 pKa = 11.84 HH2469 pKa = 3.93 NWKK2472 pKa = 7.87 VTGMGIGMPMNQSMITLYY2490 pKa = 11.04 NNLMRR2495 pKa = 11.84 SKK2497 pKa = 10.25 KK2498 pKa = 9.9 EE2499 pKa = 3.74 CGGMYY2504 pKa = 10.34 AIADD2508 pKa = 3.39 AHH2510 pKa = 6.59 EE2511 pKa = 4.49 YY2512 pKa = 10.64 DD2513 pKa = 3.79 SRR2515 pKa = 11.84 KK2516 pKa = 10.33 APFTFEE2522 pKa = 4.08 VLAKK2526 pKa = 9.97 LAEE2529 pKa = 4.01 IGYY2532 pKa = 9.09 EE2533 pKa = 4.18 GKK2535 pKa = 9.2 PQASVLKK2542 pKa = 10.17 AKK2544 pKa = 10.63 YY2545 pKa = 9.68 DD2546 pKa = 3.71 ALQSSFIFQEE2556 pKa = 4.13 TMPNHH2561 pKa = 6.41 HH2562 pKa = 7.02 NSTSVIVPDD2571 pKa = 3.9 AAIASALMKK2580 pKa = 10.18 KK2581 pKa = 9.98 HH2582 pKa = 6.43 PDD2584 pKa = 3.11 KK2585 pKa = 11.1 FITAEE2590 pKa = 4.08 LLHH2593 pKa = 6.93 SVFPRR2598 pKa = 11.84 LSQTDD2603 pKa = 4.76 LYY2605 pKa = 10.91 NDD2607 pKa = 3.13 SHH2609 pKa = 7.11 PIHH2612 pKa = 7.05 RR2613 pKa = 11.84 LYY2615 pKa = 10.92 ADD2617 pKa = 3.48 KK2618 pKa = 11.17 VVLATRR2624 pKa = 11.84 EE2625 pKa = 4.13 DD2626 pKa = 4.13 EE2627 pKa = 4.52 LTFTDD2632 pKa = 3.07 STGRR2636 pKa = 11.84 MKK2638 pKa = 10.78 YY2639 pKa = 10.07 RR2640 pKa = 11.84 LLSPIFVRR2648 pKa = 11.84 AYY2650 pKa = 10.9 LNEE2653 pKa = 3.96 QPIGSPLPFQSFQNVDD2669 pKa = 3.57 KK2670 pKa = 10.45 MKK2672 pKa = 10.2 QWLIDD2677 pKa = 3.56 EE2678 pKa = 4.43 VQPNIHH2684 pKa = 6.7 LLYY2687 pKa = 10.91 NVAQKK2692 pKa = 10.82 NRR2694 pKa = 11.84 GGGTGEE2700 pKa = 5.15 NATSWDD2706 pKa = 3.72 NGWGYY2711 pKa = 10.9 KK2712 pKa = 9.82 AAFIATWVRR2721 pKa = 11.84 YY2722 pKa = 7.95 NEE2724 pKa = 4.0 KK2725 pKa = 10.52 LGISVKK2731 pKa = 10.47 PSDD2734 pKa = 4.99 FFAQGNILYY2743 pKa = 7.86 NTGDD2747 pKa = 3.56 DD2748 pKa = 3.9 SAIKK2752 pKa = 9.22 LTGVDD2757 pKa = 2.92 TATFNKK2763 pKa = 10.29 SLWLEE2768 pKa = 3.79 CALYY2772 pKa = 10.76 YY2773 pKa = 10.82 GLEE2776 pKa = 4.18 LDD2778 pKa = 5.87 FDD2780 pKa = 4.03 FTDD2783 pKa = 4.71 DD2784 pKa = 3.54 IKK2786 pKa = 11.18 EE2787 pKa = 3.96 VEE2789 pKa = 4.27 YY2790 pKa = 10.82 LGNAIRR2796 pKa = 11.84 RR2797 pKa = 11.84 PNTDD2801 pKa = 3.84 DD2802 pKa = 4.29 LVKK2805 pKa = 10.86 LKK2807 pKa = 10.4 AWQKK2811 pKa = 10.62 MMTNVQRR2818 pKa = 11.84 SRR2820 pKa = 11.84 KK2821 pKa = 9.21 EE2822 pKa = 4.15 EE2823 pKa = 3.77 ICPPPLPRR2831 pKa = 11.84 WLVYY2835 pKa = 10.3 HH2836 pKa = 6.54 KK2837 pKa = 10.61 EE2838 pKa = 3.72 RR2839 pKa = 11.84 DD2840 pKa = 3.48 SFIRR2844 pKa = 11.84 LSSRR2848 pKa = 11.84 RR2849 pKa = 11.84 YY2850 pKa = 8.86 YY2851 pKa = 10.52 QNQPGNLSFVHH2862 pKa = 6.55 HH2863 pKa = 6.63 NLAKK2867 pKa = 10.14 FAGTATIAVFNPTLWNVLANEE2888 pKa = 4.28 YY2889 pKa = 10.83 CSDD2892 pKa = 3.71 AEE2894 pKa = 4.38 RR2895 pKa = 11.84 LAKK2898 pKa = 10.11 HH2899 pKa = 5.51 YY2900 pKa = 9.41 NVPGFTATIKK2910 pKa = 10.42 KK2911 pKa = 10.11 DD2912 pKa = 3.56 QFGLDD2917 pKa = 3.91 YY2918 pKa = 10.79 IALSDD2923 pKa = 3.6 NSNARR2928 pKa = 11.84 RR2929 pKa = 11.84 GSDD2932 pKa = 3.22 LRR2934 pKa = 11.84 RR2935 pKa = 11.84 HH2936 pKa = 5.62 LRR2938 pKa = 11.84 AHH2940 pKa = 6.29 PGYY2943 pKa = 9.54 RR2944 pKa = 11.84 LSRR2947 pKa = 11.84 QEE2949 pKa = 3.81 EE2950 pKa = 4.86 FFTFLQGAKK2959 pKa = 9.9 FPSQAKK2965 pKa = 9.6 SIRR2968 pKa = 11.84 DD2969 pKa = 3.39 ALDD2972 pKa = 2.99 IKK2974 pKa = 10.4 TEE2976 pKa = 4.14 LPVIAQQLSFIQKK2989 pKa = 10.02 LEE2991 pKa = 4.19 KK2992 pKa = 10.48 KK2993 pKa = 10.27 SGNLLDD2999 pKa = 3.86 TTNLVVDD3006 pKa = 3.99 YY3007 pKa = 10.85 LSEE3010 pKa = 3.93 EE3011 pKa = 4.0 LAAIPRR3017 pKa = 11.84 YY3018 pKa = 8.91 IYY3020 pKa = 11.32 KK3021 pKa = 8.08 MTANILPATGEE3032 pKa = 4.0 PAFASANYY3040 pKa = 8.96 PVEE3043 pKa = 4.32 HH3044 pKa = 6.51 FVAACQKK3051 pKa = 10.29 PEE3053 pKa = 4.09 TEE3055 pKa = 4.43 GFMLGKK3061 pKa = 10.14 LARR3064 pKa = 11.84 SPWASVTNGSDD3075 pKa = 4.19 FYY3077 pKa = 11.61 RR3078 pKa = 11.84 HH3079 pKa = 5.76 LQDD3082 pKa = 3.86 TEE3084 pKa = 3.82 FATNHH3089 pKa = 5.64 EE3090 pKa = 4.59 SHH3092 pKa = 6.37 TKK3094 pKa = 8.5 EE3095 pKa = 4.03 AYY3097 pKa = 9.73 GSRR3100 pKa = 11.84 LVLALVLYY3108 pKa = 10.27 CLFYY3112 pKa = 10.74 FLEE3115 pKa = 5.57 GYY3117 pKa = 9.02 FVRR3120 pKa = 11.84 IPIFGTFIRR3129 pKa = 11.84 IFYY3132 pKa = 10.27 SIMIDD3137 pKa = 3.45 VPKK3140 pKa = 10.72 VYY3142 pKa = 10.41 GVLSCLYY3149 pKa = 7.69 WHH3151 pKa = 6.92 YY3152 pKa = 11.4 YY3153 pKa = 9.19 GDD3155 pKa = 3.61 NSPIVSALMPKK3166 pKa = 10.41 DD3167 pKa = 2.89 IFIWGKK3173 pKa = 9.71 RR3174 pKa = 11.84 FAVFIAANLPMFLFDD3189 pKa = 4.04 YY3190 pKa = 9.64 PISPFYY3196 pKa = 10.24 YY3197 pKa = 10.12 LYY3199 pKa = 10.44 YY3200 pKa = 10.05 ALSFIVVPIEE3210 pKa = 3.98 TLSMLIVSGKK3220 pKa = 7.68 QQSEE3224 pKa = 4.47 HH3225 pKa = 6.82 PGSKK3229 pKa = 9.38 PHH3231 pKa = 7.01 AAPFDD3236 pKa = 3.96 NPWDD3240 pKa = 3.56 NEE3242 pKa = 3.88 VRR3244 pKa = 11.84 SEE3246 pKa = 3.94 EE3247 pKa = 4.3 GRR3249 pKa = 11.84 FQVQMRR3255 pKa = 11.84 AKK3257 pKa = 8.79 TDD3259 pKa = 3.59 LVLPPVNASSQAIVVKK3275 pKa = 10.26 DD3276 pKa = 3.6 VPRR3279 pKa = 11.84 PFVVKK3284 pKa = 10.42 SAVGSGKK3291 pKa = 10.52 SSLFPYY3297 pKa = 10.78 ALLNNAKK3304 pKa = 9.86 WIDD3307 pKa = 3.61 NFKK3310 pKa = 11.1 DD3311 pKa = 3.39 LNTPTGGRR3319 pKa = 11.84 VVLSLPRR3326 pKa = 11.84 TILRR3330 pKa = 11.84 DD3331 pKa = 3.19 KK3332 pKa = 10.31 WSSPLEE3338 pKa = 4.15 NSRR3341 pKa = 11.84 QPYY3344 pKa = 9.59 QRR3346 pKa = 11.84 LQRR3349 pKa = 11.84 GTVLDD3354 pKa = 4.48 PKK3356 pKa = 10.98 AKK3358 pKa = 10.13 ILIGTDD3364 pKa = 2.87 GHH3366 pKa = 6.65 LLNRR3370 pKa = 11.84 LKK3372 pKa = 10.88 SGEE3375 pKa = 4.1 LTEE3378 pKa = 4.37 KK3379 pKa = 10.64 DD3380 pKa = 3.18 IYY3382 pKa = 11.33 LLDD3385 pKa = 4.19 EE3386 pKa = 4.08 FHH3388 pKa = 7.06 EE3389 pKa = 4.59 LNGQKK3394 pKa = 10.03 VALFQEE3400 pKa = 4.22 LLEE3403 pKa = 4.39 RR3404 pKa = 11.84 KK3405 pKa = 9.12 CRR3407 pKa = 11.84 VMLPSATPKK3416 pKa = 9.93 PVPGINMGIMEE3427 pKa = 4.63 AAIPRR3432 pKa = 11.84 RR3433 pKa = 11.84 FAPDD3437 pKa = 2.82 IWPISDD3443 pKa = 4.14 SISPADD3449 pKa = 3.9 ALRR3452 pKa = 11.84 QFGPNFVTQWPLTGPRR3468 pKa = 11.84 DD3469 pKa = 3.62 AEE3471 pKa = 4.3 SFKK3474 pKa = 11.4 DD3475 pKa = 3.71 RR3476 pKa = 11.84 VLIKK3480 pKa = 9.57 CTHH3483 pKa = 5.39 INGRR3487 pKa = 11.84 NGVNEE3492 pKa = 4.0 TMEE3495 pKa = 4.21 ILQYY3499 pKa = 10.56 DD3500 pKa = 3.47 QWNCYY3505 pKa = 10.5 ALTSEE3510 pKa = 4.72 SARR3513 pKa = 11.84 DD3514 pKa = 4.19 PIPDD3518 pKa = 3.48 SAQVVIATDD3527 pKa = 4.01 VINTGISLPGFKK3539 pKa = 10.69 LLVYY3543 pKa = 9.57 DD3544 pKa = 4.52 GKK3546 pKa = 9.58 MHH3548 pKa = 6.7 SVHH3551 pKa = 6.81 QGEE3554 pKa = 5.03 HH3555 pKa = 4.92 QLTWTDD3561 pKa = 3.89 PDD3563 pKa = 3.85 TKK3565 pKa = 9.54 HH3566 pKa = 6.87 QGMARR3571 pKa = 11.84 VGRR3574 pKa = 11.84 YY3575 pKa = 9.6 GPGDD3579 pKa = 3.51 VVLCPVSAGTGATPQVYY3596 pKa = 8.43 PAMSYY3601 pKa = 9.96 LAWSMNAQAHH3611 pKa = 6.61 DD3612 pKa = 4.39 LPQLCSFNDD3621 pKa = 3.75 YY3622 pKa = 11.6 NEE3624 pKa = 4.36 GTSLQSKK3631 pKa = 9.96 YY3632 pKa = 10.69 EE3633 pKa = 4.22 STNLTPYY3640 pKa = 10.31 LAVSKK3645 pKa = 9.33 EE3646 pKa = 4.1 VPTFMRR3652 pKa = 11.84 DD3653 pKa = 3.34 AISVYY3658 pKa = 10.26 HH3659 pKa = 7.12 AIANMGCRR3667 pKa = 11.84 QSEE3670 pKa = 3.81 IRR3672 pKa = 11.84 GVYY3675 pKa = 10.23 NKK3677 pKa = 10.22 IIMNKK3682 pKa = 9.41 PVDD3685 pKa = 3.63 EE3686 pKa = 4.74 SYY3688 pKa = 11.63 EE3689 pKa = 3.87 LVQRR3693 pKa = 11.84 FFAPKK3698 pKa = 9.62 SRR3700 pKa = 11.84 NAMPYY3705 pKa = 8.17 EE3706 pKa = 4.05 AVVMTMAQHH3715 pKa = 6.33 PVLYY3719 pKa = 9.05 MCRR3722 pKa = 11.84 NLTPKK3727 pKa = 8.9 TQVPVATILDD3737 pKa = 4.3 LEE3739 pKa = 4.94 LSPSTPRR3746 pKa = 11.84 LYY3748 pKa = 10.54 DD3749 pKa = 3.89 AYY3751 pKa = 10.84 CCQTVNPLVPYY3762 pKa = 10.08 KK3763 pKa = 10.85 ARR3765 pKa = 11.84 LRR3767 pKa = 11.84 PLDD3770 pKa = 3.7 EE3771 pKa = 4.47 TDD3773 pKa = 3.98 SKK3775 pKa = 11.43 INNNFIIGAEE3785 pKa = 4.07 SKK3787 pKa = 10.36 PIQVYY3792 pKa = 7.27 QQIVDD3797 pKa = 2.87 IHH3799 pKa = 6.23 QSHH3802 pKa = 5.74 TRR3804 pKa = 11.84 MARR3807 pKa = 11.84 EE3808 pKa = 3.83 ALTDD3812 pKa = 3.48 ALEE3815 pKa = 4.2 AVKK3818 pKa = 10.43 DD3819 pKa = 3.78 LRR3821 pKa = 11.84 IKK3823 pKa = 10.64 KK3824 pKa = 9.58 DD3825 pKa = 3.14 WTVEE3829 pKa = 3.92 TLRR3832 pKa = 11.84 NGLRR3836 pKa = 11.84 KK3837 pKa = 10.15 CIATHH3842 pKa = 5.45 INKK3845 pKa = 9.69 LNRR3848 pKa = 11.84 EE3849 pKa = 3.83 IDD3851 pKa = 3.92 TNEE3854 pKa = 3.89 HH3855 pKa = 6.46 KK3856 pKa = 10.9 SNKK3859 pKa = 9.83 LKK3861 pKa = 11.01 FNLTEE3866 pKa = 4.02 SSRR3869 pKa = 11.84 IDD3871 pKa = 3.14 PTLAYY3876 pKa = 8.4 TIKK3879 pKa = 10.55 GGQQFIHH3886 pKa = 5.23 NHH3888 pKa = 5.84 KK3889 pKa = 9.76 LNCPMCSKK3897 pKa = 8.31 TQPHH3901 pKa = 5.11 THH3903 pKa = 5.46 VGYY3906 pKa = 11.0 NGMAEE3911 pKa = 3.92 TSYY3914 pKa = 11.17 DD3915 pKa = 3.98 YY3916 pKa = 10.87 RR3917 pKa = 11.84 DD3918 pKa = 3.07 SWIDD3922 pKa = 3.5 SLVEE3926 pKa = 3.7 TDD3928 pKa = 5.13 DD3929 pKa = 5.62 FILFHH3934 pKa = 7.49 HH3935 pKa = 7.13 GDD3937 pKa = 3.56 GLSEE3941 pKa = 4.06 NKK3943 pKa = 10.25 ASEE3946 pKa = 4.27 EE3947 pKa = 3.97 NRR3949 pKa = 11.84 KK3950 pKa = 9.38 SLHH3953 pKa = 5.24 STSGNKK3959 pKa = 9.4 RR3960 pKa = 11.84 PKK3962 pKa = 10.39 KK3963 pKa = 9.92 IGTLHH3968 pKa = 6.97 PPTT3971 pKa = 4.5
Molecular weight: 450.53 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 7.284
IPC2_protein 7.702
IPC_protein 7.454
Toseland 7.234
ProMoST 8.083
Dawson 8.214
Bjellqvist 8.565
Wikipedia 8.141
Rodwell 8.244
Grimsley 7.351
Solomon 8.229
Lehninger 8.229
Nozaki 8.668
DTASelect 8.302
Thurlkill 8.361
EMBOSS 8.404
Sillero 8.653
Patrickios 4.215
IPC_peptide 8.214
IPC2_peptide 7.483
IPC2.peptide.svr19 7.626
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
1
0
1
3971
3971
3971
3971.0
450.53
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
7.227 ± 0.0
1.511 ± 0.0
5.188 ± 0.0
5.188 ± 0.0
4.684 ± 0.0
5.137 ± 0.0
2.896 ± 0.0
5.591 ± 0.0
5.213 ± 0.0
9.318 ± 0.0
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.015 ± 0.0
4.18 ± 0.0
6.17 ± 0.0
3.677 ± 0.0
5.918 ± 0.0
7.429 ± 0.0
6.069 ± 0.0
6.346 ± 0.0
1.813 ± 0.0
4.357 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here