Rosellinia necatrix hypovirus 1

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Duplopiviricetes; Durnavirales; Hypoviridae; Hypovirus; unclassified Hypovirus

Average proteome isoelectric point is 7.28

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

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Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A2Z5WQ87|A0A2Z5WQ87_9VIRU RNA-directed RNA polymerase OS=Rosellinia necatrix hypovirus 1 OX=2032989 GN=RdRP PE=4 SV=1
MM1 pKa = 7.72NPGQKK6 pKa = 9.63RR7 pKa = 11.84GSRR10 pKa = 11.84PPQTPNYY17 pKa = 8.57SRR19 pKa = 11.84SSSRR23 pKa = 11.84STTSSVGLTSEE34 pKa = 4.04PQMLLDD40 pKa = 4.34RR41 pKa = 11.84FSAQLAEE48 pKa = 4.39QEE50 pKa = 4.21RR51 pKa = 11.84HH52 pKa = 5.71LADD55 pKa = 3.59PTSRR59 pKa = 11.84PDD61 pKa = 3.11WPICCFCPSKK71 pKa = 11.0LSVDD75 pKa = 3.76DD76 pKa = 3.64VTGKK80 pKa = 10.15IVICRR85 pKa = 11.84ACVNSHH91 pKa = 7.02DD92 pKa = 4.25EE93 pKa = 3.94IFRR96 pKa = 11.84QLEE99 pKa = 4.31AQCSPVLEE107 pKa = 4.59APSPRR112 pKa = 11.84TVLAPIEE119 pKa = 4.34EE120 pKa = 4.37EE121 pKa = 4.19PEE123 pKa = 4.07PVVSEE128 pKa = 4.16SRR130 pKa = 11.84VGIVIPVVEE139 pKa = 4.97DD140 pKa = 3.54VPAPVVEE147 pKa = 4.41PLPFLTEE154 pKa = 3.67YY155 pKa = 10.78AAPRR159 pKa = 11.84WEE161 pKa = 4.14QEE163 pKa = 3.9SLLVGGSVSRR173 pKa = 11.84PVINFPKK180 pKa = 9.56VHH182 pKa = 6.36SPSVAEE188 pKa = 3.97TSRR191 pKa = 11.84APEE194 pKa = 4.08LVFTAPKK201 pKa = 8.15TTDD204 pKa = 2.96NVTITLVVTVPGGDD218 pKa = 2.99VDD220 pKa = 3.72KK221 pKa = 10.51WLKK224 pKa = 10.55GPSRR228 pKa = 11.84MSNLDD233 pKa = 3.34WILRR237 pKa = 11.84EE238 pKa = 3.42HH239 pKa = 7.15DD240 pKa = 3.2RR241 pKa = 11.84RR242 pKa = 11.84IEE244 pKa = 3.9RR245 pKa = 11.84EE246 pKa = 3.72NRR248 pKa = 11.84SLIRR252 pKa = 11.84ASLYY256 pKa = 10.16KK257 pKa = 10.35VRR259 pKa = 11.84SKK261 pKa = 11.1AYY263 pKa = 8.17WADD266 pKa = 3.44LVSSMKK272 pKa = 9.9EE273 pKa = 3.43RR274 pKa = 11.84RR275 pKa = 11.84AVQQKK280 pKa = 10.34AYY282 pKa = 8.92RR283 pKa = 11.84TARR286 pKa = 11.84DD287 pKa = 3.32QSRR290 pKa = 11.84TAISAPLVLANKK302 pKa = 8.54FSCLTEE308 pKa = 4.0DD309 pKa = 3.39EE310 pKa = 5.47RR311 pKa = 11.84EE312 pKa = 4.11DD313 pKa = 4.29FYY315 pKa = 11.57HH316 pKa = 7.17GIIPAVRR323 pKa = 11.84PSLPTRR329 pKa = 11.84SWPKK333 pKa = 9.91RR334 pKa = 11.84KK335 pKa = 9.38RR336 pKa = 11.84APIPAEE342 pKa = 4.12KK343 pKa = 10.01KK344 pKa = 9.93KK345 pKa = 10.98SPPAPFEE352 pKa = 4.24RR353 pKa = 11.84DD354 pKa = 3.19PLLLEE359 pKa = 4.53RR360 pKa = 11.84LHH362 pKa = 7.0KK363 pKa = 10.75LLEE366 pKa = 4.28HH367 pKa = 7.27LLNQRR372 pKa = 11.84RR373 pKa = 11.84KK374 pKa = 8.98KK375 pKa = 9.18IHH377 pKa = 6.38RR378 pKa = 11.84KK379 pKa = 6.58VTVSRR384 pKa = 11.84SSCEE388 pKa = 3.91RR389 pKa = 11.84MSCPSTGTLLSTNTVKK405 pKa = 10.68RR406 pKa = 11.84AKK408 pKa = 10.04ADD410 pKa = 3.43NVGLVGIEE418 pKa = 4.24SNPGPEE424 pKa = 3.92YY425 pKa = 10.81SGPLDD430 pKa = 3.8ANFSISLTATLPCLRR445 pKa = 11.84VNYY448 pKa = 10.11SQLQAFDD455 pKa = 4.07DD456 pKa = 4.33AEE458 pKa = 4.15MAEE461 pKa = 4.44LMRR464 pKa = 11.84CGYY467 pKa = 8.32ATKK470 pKa = 10.66SPWNEE475 pKa = 3.52VSILCSWIXKK485 pKa = 7.89GQSVLGWVFSDD496 pKa = 3.82RR497 pKa = 11.84SHH499 pKa = 6.72RR500 pKa = 11.84AAAGSHH506 pKa = 4.76KK507 pKa = 10.3VAWYY511 pKa = 9.97QPTLHH516 pKa = 7.79VYY518 pKa = 7.6MQQGYY523 pKa = 6.74TGKK526 pKa = 10.49LLAYY530 pKa = 10.12RR531 pKa = 11.84FNCYY535 pKa = 7.49EE536 pKa = 3.76WSKK539 pKa = 10.5QASTAQDD546 pKa = 3.29PKK548 pKa = 10.85AIPGLEE554 pKa = 3.77QSVAEE559 pKa = 5.06DD560 pKa = 3.7FTDD563 pKa = 4.66GNWSTWFQLLQKK575 pKa = 10.18YY576 pKa = 9.3QDD578 pKa = 3.52SLRR581 pKa = 11.84ACKK584 pKa = 10.34KK585 pKa = 10.25EE586 pKa = 3.39ISEE589 pKa = 4.19LKK591 pKa = 10.32KK592 pKa = 10.37PEE594 pKa = 4.07GARR597 pKa = 11.84KK598 pKa = 8.38HH599 pKa = 6.37CKK601 pKa = 8.24HH602 pKa = 6.3HH603 pKa = 6.93VYY605 pKa = 11.08ADD607 pKa = 3.98DD608 pKa = 4.12FTLLPQTQLEE618 pKa = 4.32EE619 pKa = 4.11FRR621 pKa = 11.84NLSLNRR627 pKa = 11.84TDD629 pKa = 6.69FIDD632 pKa = 3.06IMNRR636 pKa = 11.84LTSPSVYY643 pKa = 8.87TSPYY647 pKa = 10.08IYY649 pKa = 9.59DD650 pKa = 4.3TIANLDD656 pKa = 3.65NQIGNNLTRR665 pKa = 11.84YY666 pKa = 9.38RR667 pKa = 11.84SHH669 pKa = 8.51SEE671 pKa = 3.29IKK673 pKa = 9.73IGNRR677 pKa = 11.84IHH679 pKa = 6.57SCEE682 pKa = 4.28DD683 pKa = 3.14APATTITNGLDD694 pKa = 3.44FEE696 pKa = 4.91SGSDD700 pKa = 4.43RR701 pKa = 11.84NDD703 pKa = 3.01QCSTDD708 pKa = 4.1GIVTRR713 pKa = 11.84LRR715 pKa = 11.84HH716 pKa = 6.01DD717 pKa = 3.61AQDD720 pKa = 3.33PXVRR724 pKa = 11.84DD725 pKa = 3.65LSXEE729 pKa = 4.08GLHH732 pKa = 6.52GVNFDD737 pKa = 4.05LSVSPRR743 pKa = 11.84SLPRR747 pKa = 11.84GTLEE751 pKa = 4.0FLASINYY758 pKa = 9.42DD759 pKa = 3.33HH760 pKa = 6.97VPPRR764 pKa = 11.84DD765 pKa = 3.21IVLTANRR772 pKa = 11.84MWLNDD777 pKa = 3.97LPGSPYY783 pKa = 10.02IIEE786 pKa = 4.4LRR788 pKa = 11.84STTDD792 pKa = 2.72ASHH795 pKa = 6.64IVYY798 pKa = 10.06DD799 pKa = 4.38RR800 pKa = 11.84KK801 pKa = 10.62RR802 pKa = 11.84KK803 pKa = 7.64TKK805 pKa = 9.95MIIYY809 pKa = 8.9LQGVEE814 pKa = 4.59GKK816 pKa = 9.47QLQLLRR822 pKa = 11.84FEE824 pKa = 4.94PLFHH828 pKa = 6.99LKK830 pKa = 8.28HH831 pKa = 5.24TARR834 pKa = 11.84ALVLNGGRR842 pKa = 11.84MGSKK846 pKa = 8.83WFAPYY851 pKa = 9.62RR852 pKa = 11.84QEE854 pKa = 4.28YY855 pKa = 7.14PTPQYY860 pKa = 9.84EE861 pKa = 4.33LPYY864 pKa = 9.69VYY866 pKa = 9.61PVSAGCCWIKK876 pKa = 10.5RR877 pKa = 11.84ADD879 pKa = 3.85MEE881 pKa = 4.32LHH883 pKa = 6.05KK884 pKa = 10.86VDD886 pKa = 3.24WYY888 pKa = 11.03KK889 pKa = 11.3AFSGWSGVYY898 pKa = 10.34GVDD901 pKa = 2.98EE902 pKa = 4.44NMLARR907 pKa = 11.84YY908 pKa = 8.7EE909 pKa = 4.12GFMFLRR915 pKa = 11.84GRR917 pKa = 11.84SFSTSTHH924 pKa = 6.39AGTNVPVTTHH934 pKa = 7.14FIDD937 pKa = 4.81ADD939 pKa = 3.62THH941 pKa = 4.12QTYY944 pKa = 10.02FSAYY948 pKa = 6.36WWSAKK953 pKa = 8.75IARR956 pKa = 11.84RR957 pKa = 11.84INSLTFSHH965 pKa = 5.99SQHH968 pKa = 6.15WDD970 pKa = 3.35DD971 pKa = 5.66VKK973 pKa = 11.33LLLPSQTPYY982 pKa = 11.08EE983 pKa = 4.61HH984 pKa = 7.54DD985 pKa = 4.4LDD987 pKa = 4.15PSKK990 pKa = 11.16LFGQLPGRR998 pKa = 11.84KK999 pKa = 8.73VPYY1002 pKa = 10.18DD1003 pKa = 3.84RR1004 pKa = 11.84LPTLAILDD1012 pKa = 4.49DD1013 pKa = 4.29GGKK1016 pKa = 7.91TLLCNAYY1023 pKa = 10.41DD1024 pKa = 3.64RR1025 pKa = 11.84FVTPTHH1031 pKa = 6.1SKK1033 pKa = 9.06RR1034 pKa = 11.84VIYY1037 pKa = 9.81YY1038 pKa = 8.18GHH1040 pKa = 7.41AALTPAMVDD1049 pKa = 3.84FLLTRR1054 pKa = 11.84DD1055 pKa = 3.65IILVVAEE1062 pKa = 4.54HH1063 pKa = 6.7WCASFDD1069 pKa = 3.56TSRR1072 pKa = 11.84FDD1074 pKa = 3.97IKK1076 pKa = 10.08VQRR1079 pKa = 11.84PINARR1084 pKa = 11.84RR1085 pKa = 11.84KK1086 pKa = 9.23VSYY1089 pKa = 10.18HH1090 pKa = 4.95SCEE1093 pKa = 4.17NQTSRR1098 pKa = 11.84SPLSPNDD1105 pKa = 3.4FFNEE1109 pKa = 4.17CVTFANTHH1117 pKa = 6.5LEE1119 pKa = 4.19TKK1121 pKa = 9.84IRR1123 pKa = 11.84RR1124 pKa = 11.84DD1125 pKa = 3.14PRR1127 pKa = 11.84LEE1129 pKa = 3.85VSEE1132 pKa = 4.65ANPGAKK1138 pKa = 9.55LVFGYY1143 pKa = 10.8DD1144 pKa = 3.63VFPLGYY1150 pKa = 10.5AKK1152 pKa = 10.48DD1153 pKa = 3.42SRR1155 pKa = 11.84FRR1157 pKa = 11.84VTLEE1161 pKa = 3.82NGCKK1165 pKa = 9.67VFKK1168 pKa = 10.8ANQPDD1173 pKa = 3.74ISTLRR1178 pKa = 11.84SMSRR1182 pKa = 11.84VWADD1186 pKa = 3.02PATFYY1191 pKa = 11.63AEE1193 pKa = 4.31LPQFIKK1199 pKa = 10.47PVAPEE1204 pKa = 3.87PVLNRR1209 pKa = 11.84ATINWYY1215 pKa = 10.2GYY1217 pKa = 9.3VYY1219 pKa = 10.6SIFSLLRR1226 pKa = 11.84GKK1228 pKa = 10.33AIYY1231 pKa = 8.96PIIFVALMPAVLARR1245 pKa = 11.84RR1246 pKa = 11.84QIVSAISTQTVNASRR1261 pKa = 11.84PVWNAYY1267 pKa = 7.56QASGNTYY1274 pKa = 7.79QTLNINHH1281 pKa = 7.63IYY1283 pKa = 7.93TQPLQATGNFSKK1295 pKa = 10.4FIWSLGIWVRR1305 pKa = 11.84IARR1308 pKa = 11.84QFGNVFYY1315 pKa = 11.21GLLDD1319 pKa = 3.55TAHH1322 pKa = 7.42EE1323 pKa = 4.12IGIVLVTWLAAVIFVFGIWFHH1344 pKa = 5.54LWGYY1348 pKa = 9.38KK1349 pKa = 9.02YY1350 pKa = 10.42QGIVPTILDD1359 pKa = 4.06DD1360 pKa = 3.85NALFSISDD1368 pKa = 3.41NSTPVTDD1375 pKa = 4.12EE1376 pKa = 4.62DD1377 pKa = 4.59LSEE1380 pKa = 4.23ALCIVTYY1387 pKa = 7.26GTRR1390 pKa = 11.84GDD1392 pKa = 5.05HH1393 pKa = 7.61IPMQYY1398 pKa = 10.38FGRR1401 pKa = 11.84LAALYY1406 pKa = 9.6GVRR1409 pKa = 11.84THH1411 pKa = 6.98NYY1413 pKa = 8.06QAHH1416 pKa = 6.42LGDD1419 pKa = 4.18NKK1421 pKa = 10.2TLEE1424 pKa = 4.07QLRR1427 pKa = 11.84RR1428 pKa = 11.84ADD1430 pKa = 3.61FTGLRR1435 pKa = 11.84LRR1437 pKa = 11.84YY1438 pKa = 9.38LEE1440 pKa = 5.43LMTTSLLPYY1449 pKa = 8.61KK1450 pKa = 10.4QIMQPFVHH1458 pKa = 6.86LGGKK1462 pKa = 6.33VTSYY1466 pKa = 10.19TLSPSEE1472 pKa = 4.7AFVHH1476 pKa = 5.98PLNFGGNPTLFSKK1489 pKa = 10.57FASFANRR1496 pKa = 11.84FFNPDD1501 pKa = 3.24LRR1503 pKa = 11.84VGALKK1508 pKa = 10.62EE1509 pKa = 4.35SVLPRR1514 pKa = 11.84SPDD1517 pKa = 3.15GKK1519 pKa = 10.61KK1520 pKa = 10.23LLRR1523 pKa = 11.84MLPAVTAGPEE1533 pKa = 4.14AYY1535 pKa = 8.61THH1537 pKa = 6.2GSEE1540 pKa = 4.29DD1541 pKa = 3.66ASVIPYY1547 pKa = 9.28GVKK1550 pKa = 10.03LRR1552 pKa = 11.84CPKK1555 pKa = 10.51LEE1557 pKa = 4.52SGDD1560 pKa = 3.69HH1561 pKa = 5.38QIVMRR1566 pKa = 11.84KK1567 pKa = 8.67YY1568 pKa = 9.59SGIYY1572 pKa = 8.44SHH1574 pKa = 7.07AGAGTLQTILMSGIPVEE1591 pKa = 4.39RR1592 pKa = 11.84RR1593 pKa = 11.84HH1594 pKa = 6.23ICDD1597 pKa = 3.08INIDD1601 pKa = 3.63RR1602 pKa = 11.84WYY1604 pKa = 9.41HH1605 pKa = 5.94TIPTLNDD1612 pKa = 2.94VTEE1615 pKa = 4.36RR1616 pKa = 11.84SPYY1619 pKa = 10.25VFLGYY1624 pKa = 10.48LIVKK1628 pKa = 10.02GFDD1631 pKa = 3.43LKK1633 pKa = 10.92ISLWDD1638 pKa = 3.27KK1639 pKa = 10.73FLAIGIWLFTTCTAKK1654 pKa = 10.87SFVDD1658 pKa = 4.81TIAWGYY1664 pKa = 9.7RR1665 pKa = 11.84YY1666 pKa = 10.09YY1667 pKa = 11.34AVFYY1671 pKa = 9.32GFRR1674 pKa = 11.84SILHH1678 pKa = 4.8QVILVILTFPSIAHH1692 pKa = 6.18FFGVTWLKK1700 pKa = 11.12LPLCAIASALIDD1712 pKa = 4.19APILTQMGSIWTLLYY1727 pKa = 9.42MAYY1730 pKa = 9.98QYY1732 pKa = 11.67AQFVPKK1738 pKa = 10.07VISEE1742 pKa = 3.93ISSWLDD1748 pKa = 3.17TRR1750 pKa = 11.84SEE1752 pKa = 4.05LVMTSNEE1759 pKa = 4.15SFPAPFGHH1767 pKa = 7.13WYY1769 pKa = 10.38VVDD1772 pKa = 3.44HH1773 pKa = 6.79RR1774 pKa = 11.84SGRR1777 pKa = 11.84RR1778 pKa = 11.84YY1779 pKa = 9.49EE1780 pKa = 4.26GSFSGSKK1787 pKa = 9.82GWHH1790 pKa = 5.3QKK1792 pKa = 10.39FGWIAHH1798 pKa = 4.94TRR1800 pKa = 11.84VFNNTDD1806 pKa = 3.19MEE1808 pKa = 4.54DD1809 pKa = 2.9RR1810 pKa = 11.84GYY1812 pKa = 11.18YY1813 pKa = 7.1QTLYY1817 pKa = 10.67MFITALAFIVATACLCCFSHH1837 pKa = 6.87PLISFSMVLVSIFLFAFVICEE1858 pKa = 3.88PLYY1861 pKa = 10.82QYY1863 pKa = 11.04AQYY1866 pKa = 11.47GSTQKK1871 pKa = 10.2IKK1873 pKa = 10.63KK1874 pKa = 8.73EE1875 pKa = 3.75YY1876 pKa = 10.07RR1877 pKa = 11.84IPLPFTSNTVEE1888 pKa = 4.01RR1889 pKa = 11.84MAAAYY1894 pKa = 9.45ARR1896 pKa = 11.84NEE1898 pKa = 4.17DD1899 pKa = 3.44LGGYY1903 pKa = 9.85HH1904 pKa = 7.33PFFNCQSLVIPLVYY1918 pKa = 10.57DD1919 pKa = 3.33STLFCAAFCTLVFLFTLTVLIPGWAAAVMKK1949 pKa = 9.79PLVKK1953 pKa = 10.24RR1954 pKa = 11.84LSIRR1958 pKa = 11.84IWDD1961 pKa = 3.69VSLEE1965 pKa = 4.75DD1966 pKa = 3.67ILEE1969 pKa = 4.77DD1970 pKa = 3.35IQRR1973 pKa = 11.84STNFAAAPPVKK1984 pKa = 9.77TEE1986 pKa = 4.4NVPSDD1991 pKa = 3.75PSPTPFKK1998 pKa = 10.87EE1999 pKa = 3.45RR2000 pKa = 11.84VQGYY2004 pKa = 8.7RR2005 pKa = 11.84EE2006 pKa = 3.86AGIPEE2011 pKa = 4.09VEE2013 pKa = 4.52LPQDD2017 pKa = 3.4EE2018 pKa = 4.31QAEE2021 pKa = 4.44LKK2023 pKa = 10.95LIDD2026 pKa = 3.09YY2027 pKa = 7.4WTRR2030 pKa = 11.84KK2031 pKa = 6.98FHH2033 pKa = 6.54EE2034 pKa = 4.74PLDD2037 pKa = 3.57IFEE2040 pKa = 4.51QVQTLYY2046 pKa = 10.66KK2047 pKa = 10.73LSMDD2051 pKa = 3.84PTQSHH2056 pKa = 7.06PLSEE2060 pKa = 5.32AEE2062 pKa = 4.15AEE2064 pKa = 4.49HH2065 pKa = 5.93VRR2067 pKa = 11.84AMTLAKK2073 pKa = 10.35YY2074 pKa = 10.21LEE2076 pKa = 4.2HH2077 pKa = 6.69HH2078 pKa = 6.22VSEE2081 pKa = 4.82EE2082 pKa = 4.03EE2083 pKa = 4.24VEE2085 pKa = 4.35LEE2087 pKa = 3.83ARR2089 pKa = 11.84MPGATSIIHH2098 pKa = 6.31SEE2100 pKa = 4.12MPPSQNDD2107 pKa = 3.47PTSPNAHH2114 pKa = 6.47LWAKK2118 pKa = 10.11FVGKK2122 pKa = 10.17LDD2124 pKa = 3.69EE2125 pKa = 5.43FLSIWSGEE2133 pKa = 4.07KK2134 pKa = 10.02FVSDD2138 pKa = 4.08IISWLRR2144 pKa = 11.84NQRR2147 pKa = 11.84FKK2149 pKa = 11.33HH2150 pKa = 5.74LGDD2153 pKa = 3.3LAFRR2157 pKa = 11.84VYY2159 pKa = 10.78HH2160 pKa = 6.09LLCFIGRR2167 pKa = 11.84IVYY2170 pKa = 7.53TTSFNAWRR2178 pKa = 11.84VLNLGMTCFLTCIFPVEE2195 pKa = 3.78EE2196 pKa = 4.05AKK2198 pKa = 10.55RR2199 pKa = 11.84LKK2201 pKa = 10.47SAWAFAGLTKK2211 pKa = 10.48TPFLSTKK2218 pKa = 9.94RR2219 pKa = 11.84RR2220 pKa = 11.84FVEE2223 pKa = 4.54NIAWSTKK2230 pKa = 6.97EE2231 pKa = 3.62EE2232 pKa = 4.02RR2233 pKa = 11.84GDD2235 pKa = 3.6FLEE2238 pKa = 5.15SFTSMVDD2245 pKa = 3.71EE2246 pKa = 4.7INHH2249 pKa = 4.89YY2250 pKa = 7.63CQRR2253 pKa = 11.84HH2254 pKa = 4.78GAPGIEE2260 pKa = 4.41LHH2262 pKa = 5.4PQYY2265 pKa = 10.94RR2266 pKa = 11.84KK2267 pKa = 10.34VNVGRR2272 pKa = 11.84PVLDD2276 pKa = 4.47DD2277 pKa = 3.85EE2278 pKa = 4.59QATLLGLNKK2287 pKa = 9.99DD2288 pKa = 4.02AYY2290 pKa = 10.01VTDD2293 pKa = 3.55QRR2295 pKa = 11.84STDD2298 pKa = 3.74FTRR2301 pKa = 11.84SLRR2304 pKa = 11.84EE2305 pKa = 3.45KK2306 pKa = 9.22GTPISADD2313 pKa = 3.17TVYY2316 pKa = 9.98LTDD2319 pKa = 4.42KK2320 pKa = 10.8IEE2322 pKa = 4.0YY2323 pKa = 7.95VQQSVRR2329 pKa = 11.84RR2330 pKa = 11.84YY2331 pKa = 7.6IPRR2334 pKa = 11.84YY2335 pKa = 9.18EE2336 pKa = 4.81PISHH2340 pKa = 6.75EE2341 pKa = 4.57DD2342 pKa = 3.0KK2343 pKa = 11.21LLAHH2347 pKa = 7.27EE2348 pKa = 4.64IAAEE2352 pKa = 4.1FGSRR2356 pKa = 11.84FPDD2359 pKa = 3.25SFKK2362 pKa = 10.74DD2363 pKa = 3.55AKK2365 pKa = 10.09TLTPRR2370 pKa = 11.84QVQAYY2375 pKa = 8.61YY2376 pKa = 9.61KK2377 pKa = 10.37AKK2379 pKa = 9.82YY2380 pKa = 9.9APGSPWISIYY2390 pKa = 10.52KK2391 pKa = 9.75SRR2393 pKa = 11.84QALEE2397 pKa = 3.94DD2398 pKa = 3.45AGITKK2403 pKa = 10.6ALFEE2407 pKa = 4.27MVEE2410 pKa = 4.21DD2411 pKa = 4.16RR2412 pKa = 11.84LASGKK2417 pKa = 10.33YY2418 pKa = 8.77PDD2420 pKa = 4.4MYY2422 pKa = 10.68HH2423 pKa = 6.42KK2424 pKa = 10.83AFVKK2428 pKa = 10.42SQVVNLDD2435 pKa = 3.2KK2436 pKa = 11.23VINGNKK2442 pKa = 9.16NVRR2445 pKa = 11.84TVVAQEE2451 pKa = 3.67LLTYY2455 pKa = 9.6FMNMCMEE2462 pKa = 4.61LEE2464 pKa = 4.13RR2465 pKa = 11.84NHH2467 pKa = 5.27RR2468 pKa = 11.84HH2469 pKa = 3.93NWKK2472 pKa = 7.87VTGMGIGMPMNQSMITLYY2490 pKa = 11.04NNLMRR2495 pKa = 11.84SKK2497 pKa = 10.25KK2498 pKa = 9.9EE2499 pKa = 3.74CGGMYY2504 pKa = 10.34AIADD2508 pKa = 3.39AHH2510 pKa = 6.59EE2511 pKa = 4.49YY2512 pKa = 10.64DD2513 pKa = 3.79SRR2515 pKa = 11.84KK2516 pKa = 10.33APFTFEE2522 pKa = 4.08VLAKK2526 pKa = 9.97LAEE2529 pKa = 4.01IGYY2532 pKa = 9.09EE2533 pKa = 4.18GKK2535 pKa = 9.2PQASVLKK2542 pKa = 10.17AKK2544 pKa = 10.63YY2545 pKa = 9.68DD2546 pKa = 3.71ALQSSFIFQEE2556 pKa = 4.13TMPNHH2561 pKa = 6.41HH2562 pKa = 7.02NSTSVIVPDD2571 pKa = 3.9AAIASALMKK2580 pKa = 10.18KK2581 pKa = 9.98HH2582 pKa = 6.43PDD2584 pKa = 3.11KK2585 pKa = 11.1FITAEE2590 pKa = 4.08LLHH2593 pKa = 6.93SVFPRR2598 pKa = 11.84LSQTDD2603 pKa = 4.76LYY2605 pKa = 10.91NDD2607 pKa = 3.13SHH2609 pKa = 7.11PIHH2612 pKa = 7.05RR2613 pKa = 11.84LYY2615 pKa = 10.92ADD2617 pKa = 3.48KK2618 pKa = 11.17VVLATRR2624 pKa = 11.84EE2625 pKa = 4.13DD2626 pKa = 4.13EE2627 pKa = 4.52LTFTDD2632 pKa = 3.07STGRR2636 pKa = 11.84MKK2638 pKa = 10.78YY2639 pKa = 10.07RR2640 pKa = 11.84LLSPIFVRR2648 pKa = 11.84AYY2650 pKa = 10.9LNEE2653 pKa = 3.96QPIGSPLPFQSFQNVDD2669 pKa = 3.57KK2670 pKa = 10.45MKK2672 pKa = 10.2QWLIDD2677 pKa = 3.56EE2678 pKa = 4.43VQPNIHH2684 pKa = 6.7LLYY2687 pKa = 10.91NVAQKK2692 pKa = 10.82NRR2694 pKa = 11.84GGGTGEE2700 pKa = 5.15NATSWDD2706 pKa = 3.72NGWGYY2711 pKa = 10.9KK2712 pKa = 9.82AAFIATWVRR2721 pKa = 11.84YY2722 pKa = 7.95NEE2724 pKa = 4.0KK2725 pKa = 10.52LGISVKK2731 pKa = 10.47PSDD2734 pKa = 4.99FFAQGNILYY2743 pKa = 7.86NTGDD2747 pKa = 3.56DD2748 pKa = 3.9SAIKK2752 pKa = 9.22LTGVDD2757 pKa = 2.92TATFNKK2763 pKa = 10.29SLWLEE2768 pKa = 3.79CALYY2772 pKa = 10.76YY2773 pKa = 10.82GLEE2776 pKa = 4.18LDD2778 pKa = 5.87FDD2780 pKa = 4.03FTDD2783 pKa = 4.71DD2784 pKa = 3.54IKK2786 pKa = 11.18EE2787 pKa = 3.96VEE2789 pKa = 4.27YY2790 pKa = 10.82LGNAIRR2796 pKa = 11.84RR2797 pKa = 11.84PNTDD2801 pKa = 3.84DD2802 pKa = 4.29LVKK2805 pKa = 10.86LKK2807 pKa = 10.4AWQKK2811 pKa = 10.62MMTNVQRR2818 pKa = 11.84SRR2820 pKa = 11.84KK2821 pKa = 9.21EE2822 pKa = 4.15EE2823 pKa = 3.77ICPPPLPRR2831 pKa = 11.84WLVYY2835 pKa = 10.3HH2836 pKa = 6.54KK2837 pKa = 10.61EE2838 pKa = 3.72RR2839 pKa = 11.84DD2840 pKa = 3.48SFIRR2844 pKa = 11.84LSSRR2848 pKa = 11.84RR2849 pKa = 11.84YY2850 pKa = 8.86YY2851 pKa = 10.52QNQPGNLSFVHH2862 pKa = 6.55HH2863 pKa = 6.63NLAKK2867 pKa = 10.14FAGTATIAVFNPTLWNVLANEE2888 pKa = 4.28YY2889 pKa = 10.83CSDD2892 pKa = 3.71AEE2894 pKa = 4.38RR2895 pKa = 11.84LAKK2898 pKa = 10.11HH2899 pKa = 5.51YY2900 pKa = 9.41NVPGFTATIKK2910 pKa = 10.42KK2911 pKa = 10.11DD2912 pKa = 3.56QFGLDD2917 pKa = 3.91YY2918 pKa = 10.79IALSDD2923 pKa = 3.6NSNARR2928 pKa = 11.84RR2929 pKa = 11.84GSDD2932 pKa = 3.22LRR2934 pKa = 11.84RR2935 pKa = 11.84HH2936 pKa = 5.62LRR2938 pKa = 11.84AHH2940 pKa = 6.29PGYY2943 pKa = 9.54RR2944 pKa = 11.84LSRR2947 pKa = 11.84QEE2949 pKa = 3.81EE2950 pKa = 4.86FFTFLQGAKK2959 pKa = 9.9FPSQAKK2965 pKa = 9.6SIRR2968 pKa = 11.84DD2969 pKa = 3.39ALDD2972 pKa = 2.99IKK2974 pKa = 10.4TEE2976 pKa = 4.14LPVIAQQLSFIQKK2989 pKa = 10.02LEE2991 pKa = 4.19KK2992 pKa = 10.48KK2993 pKa = 10.27SGNLLDD2999 pKa = 3.86TTNLVVDD3006 pKa = 3.99YY3007 pKa = 10.85LSEE3010 pKa = 3.93EE3011 pKa = 4.0LAAIPRR3017 pKa = 11.84YY3018 pKa = 8.91IYY3020 pKa = 11.32KK3021 pKa = 8.08MTANILPATGEE3032 pKa = 4.0PAFASANYY3040 pKa = 8.96PVEE3043 pKa = 4.32HH3044 pKa = 6.51FVAACQKK3051 pKa = 10.29PEE3053 pKa = 4.09TEE3055 pKa = 4.43GFMLGKK3061 pKa = 10.14LARR3064 pKa = 11.84SPWASVTNGSDD3075 pKa = 4.19FYY3077 pKa = 11.61RR3078 pKa = 11.84HH3079 pKa = 5.76LQDD3082 pKa = 3.86TEE3084 pKa = 3.82FATNHH3089 pKa = 5.64EE3090 pKa = 4.59SHH3092 pKa = 6.37TKK3094 pKa = 8.5EE3095 pKa = 4.03AYY3097 pKa = 9.73GSRR3100 pKa = 11.84LVLALVLYY3108 pKa = 10.27CLFYY3112 pKa = 10.74FLEE3115 pKa = 5.57GYY3117 pKa = 9.02FVRR3120 pKa = 11.84IPIFGTFIRR3129 pKa = 11.84IFYY3132 pKa = 10.27SIMIDD3137 pKa = 3.45VPKK3140 pKa = 10.72VYY3142 pKa = 10.41GVLSCLYY3149 pKa = 7.69WHH3151 pKa = 6.92YY3152 pKa = 11.4YY3153 pKa = 9.19GDD3155 pKa = 3.61NSPIVSALMPKK3166 pKa = 10.41DD3167 pKa = 2.89IFIWGKK3173 pKa = 9.71RR3174 pKa = 11.84FAVFIAANLPMFLFDD3189 pKa = 4.04YY3190 pKa = 9.64PISPFYY3196 pKa = 10.24YY3197 pKa = 10.12LYY3199 pKa = 10.44YY3200 pKa = 10.05ALSFIVVPIEE3210 pKa = 3.98TLSMLIVSGKK3220 pKa = 7.68QQSEE3224 pKa = 4.47HH3225 pKa = 6.82PGSKK3229 pKa = 9.38PHH3231 pKa = 7.01AAPFDD3236 pKa = 3.96NPWDD3240 pKa = 3.56NEE3242 pKa = 3.88VRR3244 pKa = 11.84SEE3246 pKa = 3.94EE3247 pKa = 4.3GRR3249 pKa = 11.84FQVQMRR3255 pKa = 11.84AKK3257 pKa = 8.79TDD3259 pKa = 3.59LVLPPVNASSQAIVVKK3275 pKa = 10.26DD3276 pKa = 3.6VPRR3279 pKa = 11.84PFVVKK3284 pKa = 10.42SAVGSGKK3291 pKa = 10.52SSLFPYY3297 pKa = 10.78ALLNNAKK3304 pKa = 9.86WIDD3307 pKa = 3.61NFKK3310 pKa = 11.1DD3311 pKa = 3.39LNTPTGGRR3319 pKa = 11.84VVLSLPRR3326 pKa = 11.84TILRR3330 pKa = 11.84DD3331 pKa = 3.19KK3332 pKa = 10.31WSSPLEE3338 pKa = 4.15NSRR3341 pKa = 11.84QPYY3344 pKa = 9.59QRR3346 pKa = 11.84LQRR3349 pKa = 11.84GTVLDD3354 pKa = 4.48PKK3356 pKa = 10.98AKK3358 pKa = 10.13ILIGTDD3364 pKa = 2.87GHH3366 pKa = 6.65LLNRR3370 pKa = 11.84LKK3372 pKa = 10.88SGEE3375 pKa = 4.1LTEE3378 pKa = 4.37KK3379 pKa = 10.64DD3380 pKa = 3.18IYY3382 pKa = 11.33LLDD3385 pKa = 4.19EE3386 pKa = 4.08FHH3388 pKa = 7.06EE3389 pKa = 4.59LNGQKK3394 pKa = 10.03VALFQEE3400 pKa = 4.22LLEE3403 pKa = 4.39RR3404 pKa = 11.84KK3405 pKa = 9.12CRR3407 pKa = 11.84VMLPSATPKK3416 pKa = 9.93PVPGINMGIMEE3427 pKa = 4.63AAIPRR3432 pKa = 11.84RR3433 pKa = 11.84FAPDD3437 pKa = 2.82IWPISDD3443 pKa = 4.14SISPADD3449 pKa = 3.9ALRR3452 pKa = 11.84QFGPNFVTQWPLTGPRR3468 pKa = 11.84DD3469 pKa = 3.62AEE3471 pKa = 4.3SFKK3474 pKa = 11.4DD3475 pKa = 3.71RR3476 pKa = 11.84VLIKK3480 pKa = 9.57CTHH3483 pKa = 5.39INGRR3487 pKa = 11.84NGVNEE3492 pKa = 4.0TMEE3495 pKa = 4.21ILQYY3499 pKa = 10.56DD3500 pKa = 3.47QWNCYY3505 pKa = 10.5ALTSEE3510 pKa = 4.72SARR3513 pKa = 11.84DD3514 pKa = 4.19PIPDD3518 pKa = 3.48SAQVVIATDD3527 pKa = 4.01VINTGISLPGFKK3539 pKa = 10.69LLVYY3543 pKa = 9.57DD3544 pKa = 4.52GKK3546 pKa = 9.58MHH3548 pKa = 6.7SVHH3551 pKa = 6.81QGEE3554 pKa = 5.03HH3555 pKa = 4.92QLTWTDD3561 pKa = 3.89PDD3563 pKa = 3.85TKK3565 pKa = 9.54HH3566 pKa = 6.87QGMARR3571 pKa = 11.84VGRR3574 pKa = 11.84YY3575 pKa = 9.6GPGDD3579 pKa = 3.51VVLCPVSAGTGATPQVYY3596 pKa = 8.43PAMSYY3601 pKa = 9.96LAWSMNAQAHH3611 pKa = 6.61DD3612 pKa = 4.39LPQLCSFNDD3621 pKa = 3.75YY3622 pKa = 11.6NEE3624 pKa = 4.36GTSLQSKK3631 pKa = 9.96YY3632 pKa = 10.69EE3633 pKa = 4.22STNLTPYY3640 pKa = 10.31LAVSKK3645 pKa = 9.33EE3646 pKa = 4.1VPTFMRR3652 pKa = 11.84DD3653 pKa = 3.34AISVYY3658 pKa = 10.26HH3659 pKa = 7.12AIANMGCRR3667 pKa = 11.84QSEE3670 pKa = 3.81IRR3672 pKa = 11.84GVYY3675 pKa = 10.23NKK3677 pKa = 10.22IIMNKK3682 pKa = 9.41PVDD3685 pKa = 3.63EE3686 pKa = 4.74SYY3688 pKa = 11.63EE3689 pKa = 3.87LVQRR3693 pKa = 11.84FFAPKK3698 pKa = 9.62SRR3700 pKa = 11.84NAMPYY3705 pKa = 8.17EE3706 pKa = 4.05AVVMTMAQHH3715 pKa = 6.33PVLYY3719 pKa = 9.05MCRR3722 pKa = 11.84NLTPKK3727 pKa = 8.9TQVPVATILDD3737 pKa = 4.3LEE3739 pKa = 4.94LSPSTPRR3746 pKa = 11.84LYY3748 pKa = 10.54DD3749 pKa = 3.89AYY3751 pKa = 10.84CCQTVNPLVPYY3762 pKa = 10.08KK3763 pKa = 10.85ARR3765 pKa = 11.84LRR3767 pKa = 11.84PLDD3770 pKa = 3.7EE3771 pKa = 4.47TDD3773 pKa = 3.98SKK3775 pKa = 11.43INNNFIIGAEE3785 pKa = 4.07SKK3787 pKa = 10.36PIQVYY3792 pKa = 7.27QQIVDD3797 pKa = 2.87IHH3799 pKa = 6.23QSHH3802 pKa = 5.74TRR3804 pKa = 11.84MARR3807 pKa = 11.84EE3808 pKa = 3.83ALTDD3812 pKa = 3.48ALEE3815 pKa = 4.2AVKK3818 pKa = 10.43DD3819 pKa = 3.78LRR3821 pKa = 11.84IKK3823 pKa = 10.64KK3824 pKa = 9.58DD3825 pKa = 3.14WTVEE3829 pKa = 3.92TLRR3832 pKa = 11.84NGLRR3836 pKa = 11.84KK3837 pKa = 10.15CIATHH3842 pKa = 5.45INKK3845 pKa = 9.69LNRR3848 pKa = 11.84EE3849 pKa = 3.83IDD3851 pKa = 3.92TNEE3854 pKa = 3.89HH3855 pKa = 6.46KK3856 pKa = 10.9SNKK3859 pKa = 9.83LKK3861 pKa = 11.01FNLTEE3866 pKa = 4.02SSRR3869 pKa = 11.84IDD3871 pKa = 3.14PTLAYY3876 pKa = 8.4TIKK3879 pKa = 10.55GGQQFIHH3886 pKa = 5.23NHH3888 pKa = 5.84KK3889 pKa = 9.76LNCPMCSKK3897 pKa = 8.31TQPHH3901 pKa = 5.11THH3903 pKa = 5.46VGYY3906 pKa = 11.0NGMAEE3911 pKa = 3.92TSYY3914 pKa = 11.17DD3915 pKa = 3.98YY3916 pKa = 10.87RR3917 pKa = 11.84DD3918 pKa = 3.07SWIDD3922 pKa = 3.5SLVEE3926 pKa = 3.7TDD3928 pKa = 5.13DD3929 pKa = 5.62FILFHH3934 pKa = 7.49HH3935 pKa = 7.13GDD3937 pKa = 3.56GLSEE3941 pKa = 4.06NKK3943 pKa = 10.25ASEE3946 pKa = 4.27EE3947 pKa = 3.97NRR3949 pKa = 11.84KK3950 pKa = 9.38SLHH3953 pKa = 5.24STSGNKK3959 pKa = 9.4RR3960 pKa = 11.84PKK3962 pKa = 10.39KK3963 pKa = 9.92IGTLHH3968 pKa = 6.97PPTT3971 pKa = 4.5

Molecular weight:
450.53 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A2Z5WQ87|A0A2Z5WQ87_9VIRU RNA-directed RNA polymerase OS=Rosellinia necatrix hypovirus 1 OX=2032989 GN=RdRP PE=4 SV=1
MM1 pKa = 7.72NPGQKK6 pKa = 9.63RR7 pKa = 11.84GSRR10 pKa = 11.84PPQTPNYY17 pKa = 8.57SRR19 pKa = 11.84SSSRR23 pKa = 11.84STTSSVGLTSEE34 pKa = 4.04PQMLLDD40 pKa = 4.34RR41 pKa = 11.84FSAQLAEE48 pKa = 4.39QEE50 pKa = 4.21RR51 pKa = 11.84HH52 pKa = 5.71LADD55 pKa = 3.59PTSRR59 pKa = 11.84PDD61 pKa = 3.11WPICCFCPSKK71 pKa = 11.0LSVDD75 pKa = 3.76DD76 pKa = 3.64VTGKK80 pKa = 10.15IVICRR85 pKa = 11.84ACVNSHH91 pKa = 7.02DD92 pKa = 4.25EE93 pKa = 3.94IFRR96 pKa = 11.84QLEE99 pKa = 4.31AQCSPVLEE107 pKa = 4.59APSPRR112 pKa = 11.84TVLAPIEE119 pKa = 4.34EE120 pKa = 4.37EE121 pKa = 4.19PEE123 pKa = 4.07PVVSEE128 pKa = 4.16SRR130 pKa = 11.84VGIVIPVVEE139 pKa = 4.97DD140 pKa = 3.54VPAPVVEE147 pKa = 4.41PLPFLTEE154 pKa = 3.67YY155 pKa = 10.78AAPRR159 pKa = 11.84WEE161 pKa = 4.14QEE163 pKa = 3.9SLLVGGSVSRR173 pKa = 11.84PVINFPKK180 pKa = 9.56VHH182 pKa = 6.36SPSVAEE188 pKa = 3.97TSRR191 pKa = 11.84APEE194 pKa = 4.08LVFTAPKK201 pKa = 8.15TTDD204 pKa = 2.96NVTITLVVTVPGGDD218 pKa = 2.99VDD220 pKa = 3.72KK221 pKa = 10.51WLKK224 pKa = 10.55GPSRR228 pKa = 11.84MSNLDD233 pKa = 3.34WILRR237 pKa = 11.84EE238 pKa = 3.42HH239 pKa = 7.15DD240 pKa = 3.2RR241 pKa = 11.84RR242 pKa = 11.84IEE244 pKa = 3.9RR245 pKa = 11.84EE246 pKa = 3.72NRR248 pKa = 11.84SLIRR252 pKa = 11.84ASLYY256 pKa = 10.16KK257 pKa = 10.35VRR259 pKa = 11.84SKK261 pKa = 11.1AYY263 pKa = 8.17WADD266 pKa = 3.44LVSSMKK272 pKa = 9.9EE273 pKa = 3.43RR274 pKa = 11.84RR275 pKa = 11.84AVQQKK280 pKa = 10.34AYY282 pKa = 8.92RR283 pKa = 11.84TARR286 pKa = 11.84DD287 pKa = 3.32QSRR290 pKa = 11.84TAISAPLVLANKK302 pKa = 8.54FSCLTEE308 pKa = 4.0DD309 pKa = 3.39EE310 pKa = 5.47RR311 pKa = 11.84EE312 pKa = 4.11DD313 pKa = 4.29FYY315 pKa = 11.57HH316 pKa = 7.17GIIPAVRR323 pKa = 11.84PSLPTRR329 pKa = 11.84SWPKK333 pKa = 9.91RR334 pKa = 11.84KK335 pKa = 9.38RR336 pKa = 11.84APIPAEE342 pKa = 4.12KK343 pKa = 10.01KK344 pKa = 9.93KK345 pKa = 10.98SPPAPFEE352 pKa = 4.24RR353 pKa = 11.84DD354 pKa = 3.19PLLLEE359 pKa = 4.53RR360 pKa = 11.84LHH362 pKa = 7.0KK363 pKa = 10.75LLEE366 pKa = 4.28HH367 pKa = 7.27LLNQRR372 pKa = 11.84RR373 pKa = 11.84KK374 pKa = 8.98KK375 pKa = 9.18IHH377 pKa = 6.38RR378 pKa = 11.84KK379 pKa = 6.58VTVSRR384 pKa = 11.84SSCEE388 pKa = 3.91RR389 pKa = 11.84MSCPSTGTLLSTNTVKK405 pKa = 10.68RR406 pKa = 11.84AKK408 pKa = 10.04ADD410 pKa = 3.43NVGLVGIEE418 pKa = 4.24SNPGPEE424 pKa = 3.92YY425 pKa = 10.81SGPLDD430 pKa = 3.8ANFSISLTATLPCLRR445 pKa = 11.84VNYY448 pKa = 10.11SQLQAFDD455 pKa = 4.07DD456 pKa = 4.33AEE458 pKa = 4.15MAEE461 pKa = 4.44LMRR464 pKa = 11.84CGYY467 pKa = 8.32ATKK470 pKa = 10.66SPWNEE475 pKa = 3.52VSILCSWIXKK485 pKa = 7.89GQSVLGWVFSDD496 pKa = 3.82RR497 pKa = 11.84SHH499 pKa = 6.72RR500 pKa = 11.84AAAGSHH506 pKa = 4.76KK507 pKa = 10.3VAWYY511 pKa = 9.97QPTLHH516 pKa = 7.79VYY518 pKa = 7.6MQQGYY523 pKa = 6.74TGKK526 pKa = 10.49LLAYY530 pKa = 10.12RR531 pKa = 11.84FNCYY535 pKa = 7.49EE536 pKa = 3.76WSKK539 pKa = 10.5QASTAQDD546 pKa = 3.29PKK548 pKa = 10.85AIPGLEE554 pKa = 3.77QSVAEE559 pKa = 5.06DD560 pKa = 3.7FTDD563 pKa = 4.66GNWSTWFQLLQKK575 pKa = 10.18YY576 pKa = 9.3QDD578 pKa = 3.52SLRR581 pKa = 11.84ACKK584 pKa = 10.34KK585 pKa = 10.25EE586 pKa = 3.39ISEE589 pKa = 4.19LKK591 pKa = 10.32KK592 pKa = 10.37PEE594 pKa = 4.07GARR597 pKa = 11.84KK598 pKa = 8.38HH599 pKa = 6.37CKK601 pKa = 8.24HH602 pKa = 6.3HH603 pKa = 6.93VYY605 pKa = 11.08ADD607 pKa = 3.98DD608 pKa = 4.12FTLLPQTQLEE618 pKa = 4.32EE619 pKa = 4.11FRR621 pKa = 11.84NLSLNRR627 pKa = 11.84TDD629 pKa = 6.69FIDD632 pKa = 3.06IMNRR636 pKa = 11.84LTSPSVYY643 pKa = 8.87TSPYY647 pKa = 10.08IYY649 pKa = 9.59DD650 pKa = 4.3TIANLDD656 pKa = 3.65NQIGNNLTRR665 pKa = 11.84YY666 pKa = 9.38RR667 pKa = 11.84SHH669 pKa = 8.51SEE671 pKa = 3.29IKK673 pKa = 9.73IGNRR677 pKa = 11.84IHH679 pKa = 6.57SCEE682 pKa = 4.28DD683 pKa = 3.14APATTITNGLDD694 pKa = 3.44FEE696 pKa = 4.91SGSDD700 pKa = 4.43RR701 pKa = 11.84NDD703 pKa = 3.01QCSTDD708 pKa = 4.1GIVTRR713 pKa = 11.84LRR715 pKa = 11.84HH716 pKa = 6.01DD717 pKa = 3.61AQDD720 pKa = 3.33PXVRR724 pKa = 11.84DD725 pKa = 3.65LSXEE729 pKa = 4.08GLHH732 pKa = 6.52GVNFDD737 pKa = 4.05LSVSPRR743 pKa = 11.84SLPRR747 pKa = 11.84GTLEE751 pKa = 4.0FLASINYY758 pKa = 9.42DD759 pKa = 3.33HH760 pKa = 6.97VPPRR764 pKa = 11.84DD765 pKa = 3.21IVLTANRR772 pKa = 11.84MWLNDD777 pKa = 3.97LPGSPYY783 pKa = 10.02IIEE786 pKa = 4.4LRR788 pKa = 11.84STTDD792 pKa = 2.72ASHH795 pKa = 6.64IVYY798 pKa = 10.06DD799 pKa = 4.38RR800 pKa = 11.84KK801 pKa = 10.62RR802 pKa = 11.84KK803 pKa = 7.64TKK805 pKa = 9.95MIIYY809 pKa = 8.9LQGVEE814 pKa = 4.59GKK816 pKa = 9.47QLQLLRR822 pKa = 11.84FEE824 pKa = 4.94PLFHH828 pKa = 6.99LKK830 pKa = 8.28HH831 pKa = 5.24TARR834 pKa = 11.84ALVLNGGRR842 pKa = 11.84MGSKK846 pKa = 8.83WFAPYY851 pKa = 9.62RR852 pKa = 11.84QEE854 pKa = 4.28YY855 pKa = 7.14PTPQYY860 pKa = 9.84EE861 pKa = 4.33LPYY864 pKa = 9.69VYY866 pKa = 9.61PVSAGCCWIKK876 pKa = 10.5RR877 pKa = 11.84ADD879 pKa = 3.85MEE881 pKa = 4.32LHH883 pKa = 6.05KK884 pKa = 10.86VDD886 pKa = 3.24WYY888 pKa = 11.03KK889 pKa = 11.3AFSGWSGVYY898 pKa = 10.34GVDD901 pKa = 2.98EE902 pKa = 4.44NMLARR907 pKa = 11.84YY908 pKa = 8.7EE909 pKa = 4.12GFMFLRR915 pKa = 11.84GRR917 pKa = 11.84SFSTSTHH924 pKa = 6.39AGTNVPVTTHH934 pKa = 7.14FIDD937 pKa = 4.81ADD939 pKa = 3.62THH941 pKa = 4.12QTYY944 pKa = 10.02FSAYY948 pKa = 6.36WWSAKK953 pKa = 8.75IARR956 pKa = 11.84RR957 pKa = 11.84INSLTFSHH965 pKa = 5.99SQHH968 pKa = 6.15WDD970 pKa = 3.35DD971 pKa = 5.66VKK973 pKa = 11.33LLLPSQTPYY982 pKa = 11.08EE983 pKa = 4.61HH984 pKa = 7.54DD985 pKa = 4.4LDD987 pKa = 4.15PSKK990 pKa = 11.16LFGQLPGRR998 pKa = 11.84KK999 pKa = 8.73VPYY1002 pKa = 10.18DD1003 pKa = 3.84RR1004 pKa = 11.84LPTLAILDD1012 pKa = 4.49DD1013 pKa = 4.29GGKK1016 pKa = 7.91TLLCNAYY1023 pKa = 10.41DD1024 pKa = 3.64RR1025 pKa = 11.84FVTPTHH1031 pKa = 6.1SKK1033 pKa = 9.06RR1034 pKa = 11.84VIYY1037 pKa = 9.81YY1038 pKa = 8.18GHH1040 pKa = 7.41AALTPAMVDD1049 pKa = 3.84FLLTRR1054 pKa = 11.84DD1055 pKa = 3.65IILVVAEE1062 pKa = 4.54HH1063 pKa = 6.7WCASFDD1069 pKa = 3.56TSRR1072 pKa = 11.84FDD1074 pKa = 3.97IKK1076 pKa = 10.08VQRR1079 pKa = 11.84PINARR1084 pKa = 11.84RR1085 pKa = 11.84KK1086 pKa = 9.23VSYY1089 pKa = 10.18HH1090 pKa = 4.95SCEE1093 pKa = 4.17NQTSRR1098 pKa = 11.84SPLSPNDD1105 pKa = 3.4FFNEE1109 pKa = 4.17CVTFANTHH1117 pKa = 6.5LEE1119 pKa = 4.19TKK1121 pKa = 9.84IRR1123 pKa = 11.84RR1124 pKa = 11.84DD1125 pKa = 3.14PRR1127 pKa = 11.84LEE1129 pKa = 3.85VSEE1132 pKa = 4.65ANPGAKK1138 pKa = 9.55LVFGYY1143 pKa = 10.8DD1144 pKa = 3.63VFPLGYY1150 pKa = 10.5AKK1152 pKa = 10.48DD1153 pKa = 3.42SRR1155 pKa = 11.84FRR1157 pKa = 11.84VTLEE1161 pKa = 3.82NGCKK1165 pKa = 9.67VFKK1168 pKa = 10.8ANQPDD1173 pKa = 3.74ISTLRR1178 pKa = 11.84SMSRR1182 pKa = 11.84VWADD1186 pKa = 3.02PATFYY1191 pKa = 11.63AEE1193 pKa = 4.31LPQFIKK1199 pKa = 10.47PVAPEE1204 pKa = 3.87PVLNRR1209 pKa = 11.84ATINWYY1215 pKa = 10.2GYY1217 pKa = 9.3VYY1219 pKa = 10.6SIFSLLRR1226 pKa = 11.84GKK1228 pKa = 10.33AIYY1231 pKa = 8.96PIIFVALMPAVLARR1245 pKa = 11.84RR1246 pKa = 11.84QIVSAISTQTVNASRR1261 pKa = 11.84PVWNAYY1267 pKa = 7.56QASGNTYY1274 pKa = 7.79QTLNINHH1281 pKa = 7.63IYY1283 pKa = 7.93TQPLQATGNFSKK1295 pKa = 10.4FIWSLGIWVRR1305 pKa = 11.84IARR1308 pKa = 11.84QFGNVFYY1315 pKa = 11.21GLLDD1319 pKa = 3.55TAHH1322 pKa = 7.42EE1323 pKa = 4.12IGIVLVTWLAAVIFVFGIWFHH1344 pKa = 5.54LWGYY1348 pKa = 9.38KK1349 pKa = 9.02YY1350 pKa = 10.42QGIVPTILDD1359 pKa = 4.06DD1360 pKa = 3.85NALFSISDD1368 pKa = 3.41NSTPVTDD1375 pKa = 4.12EE1376 pKa = 4.62DD1377 pKa = 4.59LSEE1380 pKa = 4.23ALCIVTYY1387 pKa = 7.26GTRR1390 pKa = 11.84GDD1392 pKa = 5.05HH1393 pKa = 7.61IPMQYY1398 pKa = 10.38FGRR1401 pKa = 11.84LAALYY1406 pKa = 9.6GVRR1409 pKa = 11.84THH1411 pKa = 6.98NYY1413 pKa = 8.06QAHH1416 pKa = 6.42LGDD1419 pKa = 4.18NKK1421 pKa = 10.2TLEE1424 pKa = 4.07QLRR1427 pKa = 11.84RR1428 pKa = 11.84ADD1430 pKa = 3.61FTGLRR1435 pKa = 11.84LRR1437 pKa = 11.84YY1438 pKa = 9.38LEE1440 pKa = 5.43LMTTSLLPYY1449 pKa = 8.61KK1450 pKa = 10.4QIMQPFVHH1458 pKa = 6.86LGGKK1462 pKa = 6.33VTSYY1466 pKa = 10.19TLSPSEE1472 pKa = 4.7AFVHH1476 pKa = 5.98PLNFGGNPTLFSKK1489 pKa = 10.57FASFANRR1496 pKa = 11.84FFNPDD1501 pKa = 3.24LRR1503 pKa = 11.84VGALKK1508 pKa = 10.62EE1509 pKa = 4.35SVLPRR1514 pKa = 11.84SPDD1517 pKa = 3.15GKK1519 pKa = 10.61KK1520 pKa = 10.23LLRR1523 pKa = 11.84MLPAVTAGPEE1533 pKa = 4.14AYY1535 pKa = 8.61THH1537 pKa = 6.2GSEE1540 pKa = 4.29DD1541 pKa = 3.66ASVIPYY1547 pKa = 9.28GVKK1550 pKa = 10.03LRR1552 pKa = 11.84CPKK1555 pKa = 10.51LEE1557 pKa = 4.52SGDD1560 pKa = 3.69HH1561 pKa = 5.38QIVMRR1566 pKa = 11.84KK1567 pKa = 8.67YY1568 pKa = 9.59SGIYY1572 pKa = 8.44SHH1574 pKa = 7.07AGAGTLQTILMSGIPVEE1591 pKa = 4.39RR1592 pKa = 11.84RR1593 pKa = 11.84HH1594 pKa = 6.23ICDD1597 pKa = 3.08INIDD1601 pKa = 3.63RR1602 pKa = 11.84WYY1604 pKa = 9.41HH1605 pKa = 5.94TIPTLNDD1612 pKa = 2.94VTEE1615 pKa = 4.36RR1616 pKa = 11.84SPYY1619 pKa = 10.25VFLGYY1624 pKa = 10.48LIVKK1628 pKa = 10.02GFDD1631 pKa = 3.43LKK1633 pKa = 10.92ISLWDD1638 pKa = 3.27KK1639 pKa = 10.73FLAIGIWLFTTCTAKK1654 pKa = 10.87SFVDD1658 pKa = 4.81TIAWGYY1664 pKa = 9.7RR1665 pKa = 11.84YY1666 pKa = 10.09YY1667 pKa = 11.34AVFYY1671 pKa = 9.32GFRR1674 pKa = 11.84SILHH1678 pKa = 4.8QVILVILTFPSIAHH1692 pKa = 6.18FFGVTWLKK1700 pKa = 11.12LPLCAIASALIDD1712 pKa = 4.19APILTQMGSIWTLLYY1727 pKa = 9.42MAYY1730 pKa = 9.98QYY1732 pKa = 11.67AQFVPKK1738 pKa = 10.07VISEE1742 pKa = 3.93ISSWLDD1748 pKa = 3.17TRR1750 pKa = 11.84SEE1752 pKa = 4.05LVMTSNEE1759 pKa = 4.15SFPAPFGHH1767 pKa = 7.13WYY1769 pKa = 10.38VVDD1772 pKa = 3.44HH1773 pKa = 6.79RR1774 pKa = 11.84SGRR1777 pKa = 11.84RR1778 pKa = 11.84YY1779 pKa = 9.49EE1780 pKa = 4.26GSFSGSKK1787 pKa = 9.82GWHH1790 pKa = 5.3QKK1792 pKa = 10.39FGWIAHH1798 pKa = 4.94TRR1800 pKa = 11.84VFNNTDD1806 pKa = 3.19MEE1808 pKa = 4.54DD1809 pKa = 2.9RR1810 pKa = 11.84GYY1812 pKa = 11.18YY1813 pKa = 7.1QTLYY1817 pKa = 10.67MFITALAFIVATACLCCFSHH1837 pKa = 6.87PLISFSMVLVSIFLFAFVICEE1858 pKa = 3.88PLYY1861 pKa = 10.82QYY1863 pKa = 11.04AQYY1866 pKa = 11.47GSTQKK1871 pKa = 10.2IKK1873 pKa = 10.63KK1874 pKa = 8.73EE1875 pKa = 3.75YY1876 pKa = 10.07RR1877 pKa = 11.84IPLPFTSNTVEE1888 pKa = 4.01RR1889 pKa = 11.84MAAAYY1894 pKa = 9.45ARR1896 pKa = 11.84NEE1898 pKa = 4.17DD1899 pKa = 3.44LGGYY1903 pKa = 9.85HH1904 pKa = 7.33PFFNCQSLVIPLVYY1918 pKa = 10.57DD1919 pKa = 3.33STLFCAAFCTLVFLFTLTVLIPGWAAAVMKK1949 pKa = 9.79PLVKK1953 pKa = 10.24RR1954 pKa = 11.84LSIRR1958 pKa = 11.84IWDD1961 pKa = 3.69VSLEE1965 pKa = 4.75DD1966 pKa = 3.67ILEE1969 pKa = 4.77DD1970 pKa = 3.35IQRR1973 pKa = 11.84STNFAAAPPVKK1984 pKa = 9.77TEE1986 pKa = 4.4NVPSDD1991 pKa = 3.75PSPTPFKK1998 pKa = 10.87EE1999 pKa = 3.45RR2000 pKa = 11.84VQGYY2004 pKa = 8.7RR2005 pKa = 11.84EE2006 pKa = 3.86AGIPEE2011 pKa = 4.09VEE2013 pKa = 4.52LPQDD2017 pKa = 3.4EE2018 pKa = 4.31QAEE2021 pKa = 4.44LKK2023 pKa = 10.95LIDD2026 pKa = 3.09YY2027 pKa = 7.4WTRR2030 pKa = 11.84KK2031 pKa = 6.98FHH2033 pKa = 6.54EE2034 pKa = 4.74PLDD2037 pKa = 3.57IFEE2040 pKa = 4.51QVQTLYY2046 pKa = 10.66KK2047 pKa = 10.73LSMDD2051 pKa = 3.84PTQSHH2056 pKa = 7.06PLSEE2060 pKa = 5.32AEE2062 pKa = 4.15AEE2064 pKa = 4.49HH2065 pKa = 5.93VRR2067 pKa = 11.84AMTLAKK2073 pKa = 10.35YY2074 pKa = 10.21LEE2076 pKa = 4.2HH2077 pKa = 6.69HH2078 pKa = 6.22VSEE2081 pKa = 4.82EE2082 pKa = 4.03EE2083 pKa = 4.24VEE2085 pKa = 4.35LEE2087 pKa = 3.83ARR2089 pKa = 11.84MPGATSIIHH2098 pKa = 6.31SEE2100 pKa = 4.12MPPSQNDD2107 pKa = 3.47PTSPNAHH2114 pKa = 6.47LWAKK2118 pKa = 10.11FVGKK2122 pKa = 10.17LDD2124 pKa = 3.69EE2125 pKa = 5.43FLSIWSGEE2133 pKa = 4.07KK2134 pKa = 10.02FVSDD2138 pKa = 4.08IISWLRR2144 pKa = 11.84NQRR2147 pKa = 11.84FKK2149 pKa = 11.33HH2150 pKa = 5.74LGDD2153 pKa = 3.3LAFRR2157 pKa = 11.84VYY2159 pKa = 10.78HH2160 pKa = 6.09LLCFIGRR2167 pKa = 11.84IVYY2170 pKa = 7.53TTSFNAWRR2178 pKa = 11.84VLNLGMTCFLTCIFPVEE2195 pKa = 3.78EE2196 pKa = 4.05AKK2198 pKa = 10.55RR2199 pKa = 11.84LKK2201 pKa = 10.47SAWAFAGLTKK2211 pKa = 10.48TPFLSTKK2218 pKa = 9.94RR2219 pKa = 11.84RR2220 pKa = 11.84FVEE2223 pKa = 4.54NIAWSTKK2230 pKa = 6.97EE2231 pKa = 3.62EE2232 pKa = 4.02RR2233 pKa = 11.84GDD2235 pKa = 3.6FLEE2238 pKa = 5.15SFTSMVDD2245 pKa = 3.71EE2246 pKa = 4.7INHH2249 pKa = 4.89YY2250 pKa = 7.63CQRR2253 pKa = 11.84HH2254 pKa = 4.78GAPGIEE2260 pKa = 4.41LHH2262 pKa = 5.4PQYY2265 pKa = 10.94RR2266 pKa = 11.84KK2267 pKa = 10.34VNVGRR2272 pKa = 11.84PVLDD2276 pKa = 4.47DD2277 pKa = 3.85EE2278 pKa = 4.59QATLLGLNKK2287 pKa = 9.99DD2288 pKa = 4.02AYY2290 pKa = 10.01VTDD2293 pKa = 3.55QRR2295 pKa = 11.84STDD2298 pKa = 3.74FTRR2301 pKa = 11.84SLRR2304 pKa = 11.84EE2305 pKa = 3.45KK2306 pKa = 9.22GTPISADD2313 pKa = 3.17TVYY2316 pKa = 9.98LTDD2319 pKa = 4.42KK2320 pKa = 10.8IEE2322 pKa = 4.0YY2323 pKa = 7.95VQQSVRR2329 pKa = 11.84RR2330 pKa = 11.84YY2331 pKa = 7.6IPRR2334 pKa = 11.84YY2335 pKa = 9.18EE2336 pKa = 4.81PISHH2340 pKa = 6.75EE2341 pKa = 4.57DD2342 pKa = 3.0KK2343 pKa = 11.21LLAHH2347 pKa = 7.27EE2348 pKa = 4.64IAAEE2352 pKa = 4.1FGSRR2356 pKa = 11.84FPDD2359 pKa = 3.25SFKK2362 pKa = 10.74DD2363 pKa = 3.55AKK2365 pKa = 10.09TLTPRR2370 pKa = 11.84QVQAYY2375 pKa = 8.61YY2376 pKa = 9.61KK2377 pKa = 10.37AKK2379 pKa = 9.82YY2380 pKa = 9.9APGSPWISIYY2390 pKa = 10.52KK2391 pKa = 9.75SRR2393 pKa = 11.84QALEE2397 pKa = 3.94DD2398 pKa = 3.45AGITKK2403 pKa = 10.6ALFEE2407 pKa = 4.27MVEE2410 pKa = 4.21DD2411 pKa = 4.16RR2412 pKa = 11.84LASGKK2417 pKa = 10.33YY2418 pKa = 8.77PDD2420 pKa = 4.4MYY2422 pKa = 10.68HH2423 pKa = 6.42KK2424 pKa = 10.83AFVKK2428 pKa = 10.42SQVVNLDD2435 pKa = 3.2KK2436 pKa = 11.23VINGNKK2442 pKa = 9.16NVRR2445 pKa = 11.84TVVAQEE2451 pKa = 3.67LLTYY2455 pKa = 9.6FMNMCMEE2462 pKa = 4.61LEE2464 pKa = 4.13RR2465 pKa = 11.84NHH2467 pKa = 5.27RR2468 pKa = 11.84HH2469 pKa = 3.93NWKK2472 pKa = 7.87VTGMGIGMPMNQSMITLYY2490 pKa = 11.04NNLMRR2495 pKa = 11.84SKK2497 pKa = 10.25KK2498 pKa = 9.9EE2499 pKa = 3.74CGGMYY2504 pKa = 10.34AIADD2508 pKa = 3.39AHH2510 pKa = 6.59EE2511 pKa = 4.49YY2512 pKa = 10.64DD2513 pKa = 3.79SRR2515 pKa = 11.84KK2516 pKa = 10.33APFTFEE2522 pKa = 4.08VLAKK2526 pKa = 9.97LAEE2529 pKa = 4.01IGYY2532 pKa = 9.09EE2533 pKa = 4.18GKK2535 pKa = 9.2PQASVLKK2542 pKa = 10.17AKK2544 pKa = 10.63YY2545 pKa = 9.68DD2546 pKa = 3.71ALQSSFIFQEE2556 pKa = 4.13TMPNHH2561 pKa = 6.41HH2562 pKa = 7.02NSTSVIVPDD2571 pKa = 3.9AAIASALMKK2580 pKa = 10.18KK2581 pKa = 9.98HH2582 pKa = 6.43PDD2584 pKa = 3.11KK2585 pKa = 11.1FITAEE2590 pKa = 4.08LLHH2593 pKa = 6.93SVFPRR2598 pKa = 11.84LSQTDD2603 pKa = 4.76LYY2605 pKa = 10.91NDD2607 pKa = 3.13SHH2609 pKa = 7.11PIHH2612 pKa = 7.05RR2613 pKa = 11.84LYY2615 pKa = 10.92ADD2617 pKa = 3.48KK2618 pKa = 11.17VVLATRR2624 pKa = 11.84EE2625 pKa = 4.13DD2626 pKa = 4.13EE2627 pKa = 4.52LTFTDD2632 pKa = 3.07STGRR2636 pKa = 11.84MKK2638 pKa = 10.78YY2639 pKa = 10.07RR2640 pKa = 11.84LLSPIFVRR2648 pKa = 11.84AYY2650 pKa = 10.9LNEE2653 pKa = 3.96QPIGSPLPFQSFQNVDD2669 pKa = 3.57KK2670 pKa = 10.45MKK2672 pKa = 10.2QWLIDD2677 pKa = 3.56EE2678 pKa = 4.43VQPNIHH2684 pKa = 6.7LLYY2687 pKa = 10.91NVAQKK2692 pKa = 10.82NRR2694 pKa = 11.84GGGTGEE2700 pKa = 5.15NATSWDD2706 pKa = 3.72NGWGYY2711 pKa = 10.9KK2712 pKa = 9.82AAFIATWVRR2721 pKa = 11.84YY2722 pKa = 7.95NEE2724 pKa = 4.0KK2725 pKa = 10.52LGISVKK2731 pKa = 10.47PSDD2734 pKa = 4.99FFAQGNILYY2743 pKa = 7.86NTGDD2747 pKa = 3.56DD2748 pKa = 3.9SAIKK2752 pKa = 9.22LTGVDD2757 pKa = 2.92TATFNKK2763 pKa = 10.29SLWLEE2768 pKa = 3.79CALYY2772 pKa = 10.76YY2773 pKa = 10.82GLEE2776 pKa = 4.18LDD2778 pKa = 5.87FDD2780 pKa = 4.03FTDD2783 pKa = 4.71DD2784 pKa = 3.54IKK2786 pKa = 11.18EE2787 pKa = 3.96VEE2789 pKa = 4.27YY2790 pKa = 10.82LGNAIRR2796 pKa = 11.84RR2797 pKa = 11.84PNTDD2801 pKa = 3.84DD2802 pKa = 4.29LVKK2805 pKa = 10.86LKK2807 pKa = 10.4AWQKK2811 pKa = 10.62MMTNVQRR2818 pKa = 11.84SRR2820 pKa = 11.84KK2821 pKa = 9.21EE2822 pKa = 4.15EE2823 pKa = 3.77ICPPPLPRR2831 pKa = 11.84WLVYY2835 pKa = 10.3HH2836 pKa = 6.54KK2837 pKa = 10.61EE2838 pKa = 3.72RR2839 pKa = 11.84DD2840 pKa = 3.48SFIRR2844 pKa = 11.84LSSRR2848 pKa = 11.84RR2849 pKa = 11.84YY2850 pKa = 8.86YY2851 pKa = 10.52QNQPGNLSFVHH2862 pKa = 6.55HH2863 pKa = 6.63NLAKK2867 pKa = 10.14FAGTATIAVFNPTLWNVLANEE2888 pKa = 4.28YY2889 pKa = 10.83CSDD2892 pKa = 3.71AEE2894 pKa = 4.38RR2895 pKa = 11.84LAKK2898 pKa = 10.11HH2899 pKa = 5.51YY2900 pKa = 9.41NVPGFTATIKK2910 pKa = 10.42KK2911 pKa = 10.11DD2912 pKa = 3.56QFGLDD2917 pKa = 3.91YY2918 pKa = 10.79IALSDD2923 pKa = 3.6NSNARR2928 pKa = 11.84RR2929 pKa = 11.84GSDD2932 pKa = 3.22LRR2934 pKa = 11.84RR2935 pKa = 11.84HH2936 pKa = 5.62LRR2938 pKa = 11.84AHH2940 pKa = 6.29PGYY2943 pKa = 9.54RR2944 pKa = 11.84LSRR2947 pKa = 11.84QEE2949 pKa = 3.81EE2950 pKa = 4.86FFTFLQGAKK2959 pKa = 9.9FPSQAKK2965 pKa = 9.6SIRR2968 pKa = 11.84DD2969 pKa = 3.39ALDD2972 pKa = 2.99IKK2974 pKa = 10.4TEE2976 pKa = 4.14LPVIAQQLSFIQKK2989 pKa = 10.02LEE2991 pKa = 4.19KK2992 pKa = 10.48KK2993 pKa = 10.27SGNLLDD2999 pKa = 3.86TTNLVVDD3006 pKa = 3.99YY3007 pKa = 10.85LSEE3010 pKa = 3.93EE3011 pKa = 4.0LAAIPRR3017 pKa = 11.84YY3018 pKa = 8.91IYY3020 pKa = 11.32KK3021 pKa = 8.08MTANILPATGEE3032 pKa = 4.0PAFASANYY3040 pKa = 8.96PVEE3043 pKa = 4.32HH3044 pKa = 6.51FVAACQKK3051 pKa = 10.29PEE3053 pKa = 4.09TEE3055 pKa = 4.43GFMLGKK3061 pKa = 10.14LARR3064 pKa = 11.84SPWASVTNGSDD3075 pKa = 4.19FYY3077 pKa = 11.61RR3078 pKa = 11.84HH3079 pKa = 5.76LQDD3082 pKa = 3.86TEE3084 pKa = 3.82FATNHH3089 pKa = 5.64EE3090 pKa = 4.59SHH3092 pKa = 6.37TKK3094 pKa = 8.5EE3095 pKa = 4.03AYY3097 pKa = 9.73GSRR3100 pKa = 11.84LVLALVLYY3108 pKa = 10.27CLFYY3112 pKa = 10.74FLEE3115 pKa = 5.57GYY3117 pKa = 9.02FVRR3120 pKa = 11.84IPIFGTFIRR3129 pKa = 11.84IFYY3132 pKa = 10.27SIMIDD3137 pKa = 3.45VPKK3140 pKa = 10.72VYY3142 pKa = 10.41GVLSCLYY3149 pKa = 7.69WHH3151 pKa = 6.92YY3152 pKa = 11.4YY3153 pKa = 9.19GDD3155 pKa = 3.61NSPIVSALMPKK3166 pKa = 10.41DD3167 pKa = 2.89IFIWGKK3173 pKa = 9.71RR3174 pKa = 11.84FAVFIAANLPMFLFDD3189 pKa = 4.04YY3190 pKa = 9.64PISPFYY3196 pKa = 10.24YY3197 pKa = 10.12LYY3199 pKa = 10.44YY3200 pKa = 10.05ALSFIVVPIEE3210 pKa = 3.98TLSMLIVSGKK3220 pKa = 7.68QQSEE3224 pKa = 4.47HH3225 pKa = 6.82PGSKK3229 pKa = 9.38PHH3231 pKa = 7.01AAPFDD3236 pKa = 3.96NPWDD3240 pKa = 3.56NEE3242 pKa = 3.88VRR3244 pKa = 11.84SEE3246 pKa = 3.94EE3247 pKa = 4.3GRR3249 pKa = 11.84FQVQMRR3255 pKa = 11.84AKK3257 pKa = 8.79TDD3259 pKa = 3.59LVLPPVNASSQAIVVKK3275 pKa = 10.26DD3276 pKa = 3.6VPRR3279 pKa = 11.84PFVVKK3284 pKa = 10.42SAVGSGKK3291 pKa = 10.52SSLFPYY3297 pKa = 10.78ALLNNAKK3304 pKa = 9.86WIDD3307 pKa = 3.61NFKK3310 pKa = 11.1DD3311 pKa = 3.39LNTPTGGRR3319 pKa = 11.84VVLSLPRR3326 pKa = 11.84TILRR3330 pKa = 11.84DD3331 pKa = 3.19KK3332 pKa = 10.31WSSPLEE3338 pKa = 4.15NSRR3341 pKa = 11.84QPYY3344 pKa = 9.59QRR3346 pKa = 11.84LQRR3349 pKa = 11.84GTVLDD3354 pKa = 4.48PKK3356 pKa = 10.98AKK3358 pKa = 10.13ILIGTDD3364 pKa = 2.87GHH3366 pKa = 6.65LLNRR3370 pKa = 11.84LKK3372 pKa = 10.88SGEE3375 pKa = 4.1LTEE3378 pKa = 4.37KK3379 pKa = 10.64DD3380 pKa = 3.18IYY3382 pKa = 11.33LLDD3385 pKa = 4.19EE3386 pKa = 4.08FHH3388 pKa = 7.06EE3389 pKa = 4.59LNGQKK3394 pKa = 10.03VALFQEE3400 pKa = 4.22LLEE3403 pKa = 4.39RR3404 pKa = 11.84KK3405 pKa = 9.12CRR3407 pKa = 11.84VMLPSATPKK3416 pKa = 9.93PVPGINMGIMEE3427 pKa = 4.63AAIPRR3432 pKa = 11.84RR3433 pKa = 11.84FAPDD3437 pKa = 2.82IWPISDD3443 pKa = 4.14SISPADD3449 pKa = 3.9ALRR3452 pKa = 11.84QFGPNFVTQWPLTGPRR3468 pKa = 11.84DD3469 pKa = 3.62AEE3471 pKa = 4.3SFKK3474 pKa = 11.4DD3475 pKa = 3.71RR3476 pKa = 11.84VLIKK3480 pKa = 9.57CTHH3483 pKa = 5.39INGRR3487 pKa = 11.84NGVNEE3492 pKa = 4.0TMEE3495 pKa = 4.21ILQYY3499 pKa = 10.56DD3500 pKa = 3.47QWNCYY3505 pKa = 10.5ALTSEE3510 pKa = 4.72SARR3513 pKa = 11.84DD3514 pKa = 4.19PIPDD3518 pKa = 3.48SAQVVIATDD3527 pKa = 4.01VINTGISLPGFKK3539 pKa = 10.69LLVYY3543 pKa = 9.57DD3544 pKa = 4.52GKK3546 pKa = 9.58MHH3548 pKa = 6.7SVHH3551 pKa = 6.81QGEE3554 pKa = 5.03HH3555 pKa = 4.92QLTWTDD3561 pKa = 3.89PDD3563 pKa = 3.85TKK3565 pKa = 9.54HH3566 pKa = 6.87QGMARR3571 pKa = 11.84VGRR3574 pKa = 11.84YY3575 pKa = 9.6GPGDD3579 pKa = 3.51VVLCPVSAGTGATPQVYY3596 pKa = 8.43PAMSYY3601 pKa = 9.96LAWSMNAQAHH3611 pKa = 6.61DD3612 pKa = 4.39LPQLCSFNDD3621 pKa = 3.75YY3622 pKa = 11.6NEE3624 pKa = 4.36GTSLQSKK3631 pKa = 9.96YY3632 pKa = 10.69EE3633 pKa = 4.22STNLTPYY3640 pKa = 10.31LAVSKK3645 pKa = 9.33EE3646 pKa = 4.1VPTFMRR3652 pKa = 11.84DD3653 pKa = 3.34AISVYY3658 pKa = 10.26HH3659 pKa = 7.12AIANMGCRR3667 pKa = 11.84QSEE3670 pKa = 3.81IRR3672 pKa = 11.84GVYY3675 pKa = 10.23NKK3677 pKa = 10.22IIMNKK3682 pKa = 9.41PVDD3685 pKa = 3.63EE3686 pKa = 4.74SYY3688 pKa = 11.63EE3689 pKa = 3.87LVQRR3693 pKa = 11.84FFAPKK3698 pKa = 9.62SRR3700 pKa = 11.84NAMPYY3705 pKa = 8.17EE3706 pKa = 4.05AVVMTMAQHH3715 pKa = 6.33PVLYY3719 pKa = 9.05MCRR3722 pKa = 11.84NLTPKK3727 pKa = 8.9TQVPVATILDD3737 pKa = 4.3LEE3739 pKa = 4.94LSPSTPRR3746 pKa = 11.84LYY3748 pKa = 10.54DD3749 pKa = 3.89AYY3751 pKa = 10.84CCQTVNPLVPYY3762 pKa = 10.08KK3763 pKa = 10.85ARR3765 pKa = 11.84LRR3767 pKa = 11.84PLDD3770 pKa = 3.7EE3771 pKa = 4.47TDD3773 pKa = 3.98SKK3775 pKa = 11.43INNNFIIGAEE3785 pKa = 4.07SKK3787 pKa = 10.36PIQVYY3792 pKa = 7.27QQIVDD3797 pKa = 2.87IHH3799 pKa = 6.23QSHH3802 pKa = 5.74TRR3804 pKa = 11.84MARR3807 pKa = 11.84EE3808 pKa = 3.83ALTDD3812 pKa = 3.48ALEE3815 pKa = 4.2AVKK3818 pKa = 10.43DD3819 pKa = 3.78LRR3821 pKa = 11.84IKK3823 pKa = 10.64KK3824 pKa = 9.58DD3825 pKa = 3.14WTVEE3829 pKa = 3.92TLRR3832 pKa = 11.84NGLRR3836 pKa = 11.84KK3837 pKa = 10.15CIATHH3842 pKa = 5.45INKK3845 pKa = 9.69LNRR3848 pKa = 11.84EE3849 pKa = 3.83IDD3851 pKa = 3.92TNEE3854 pKa = 3.89HH3855 pKa = 6.46KK3856 pKa = 10.9SNKK3859 pKa = 9.83LKK3861 pKa = 11.01FNLTEE3866 pKa = 4.02SSRR3869 pKa = 11.84IDD3871 pKa = 3.14PTLAYY3876 pKa = 8.4TIKK3879 pKa = 10.55GGQQFIHH3886 pKa = 5.23NHH3888 pKa = 5.84KK3889 pKa = 9.76LNCPMCSKK3897 pKa = 8.31TQPHH3901 pKa = 5.11THH3903 pKa = 5.46VGYY3906 pKa = 11.0NGMAEE3911 pKa = 3.92TSYY3914 pKa = 11.17DD3915 pKa = 3.98YY3916 pKa = 10.87RR3917 pKa = 11.84DD3918 pKa = 3.07SWIDD3922 pKa = 3.5SLVEE3926 pKa = 3.7TDD3928 pKa = 5.13DD3929 pKa = 5.62FILFHH3934 pKa = 7.49HH3935 pKa = 7.13GDD3937 pKa = 3.56GLSEE3941 pKa = 4.06NKK3943 pKa = 10.25ASEE3946 pKa = 4.27EE3947 pKa = 3.97NRR3949 pKa = 11.84KK3950 pKa = 9.38SLHH3953 pKa = 5.24STSGNKK3959 pKa = 9.4RR3960 pKa = 11.84PKK3962 pKa = 10.39KK3963 pKa = 9.92IGTLHH3968 pKa = 6.97PPTT3971 pKa = 4.5

Molecular weight:
450.53 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

3971

3971

3971

3971.0

450.53

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.227 ± 0.0

1.511 ± 0.0

5.188 ± 0.0

5.188 ± 0.0

4.684 ± 0.0

5.137 ± 0.0

2.896 ± 0.0

5.591 ± 0.0

5.213 ± 0.0

9.318 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.015 ± 0.0

4.18 ± 0.0

6.17 ± 0.0

3.677 ± 0.0

5.918 ± 0.0

7.429 ± 0.0

6.069 ± 0.0

6.346 ± 0.0

1.813 ± 0.0

4.357 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski