Amino acid dipepetide frequency for Wenzhou picorna-like virus 23

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.114AlaAla: 3.114 ± 0.0
0.346AlaCys: 0.346 ± 0.0
1.384AlaAsp: 1.384 ± 0.0
3.114AlaGlu: 3.114 ± 0.0
2.076AlaPhe: 2.076 ± 0.0
4.498AlaGly: 4.498 ± 0.0
0.692AlaHis: 0.692 ± 0.0
4.844AlaIle: 4.844 ± 0.0
3.46AlaLys: 3.46 ± 0.0
2.768AlaLeu: 2.768 ± 0.0
0.346AlaMet: 0.346 ± 0.0
3.806AlaAsn: 3.806 ± 0.0
1.384AlaPro: 1.384 ± 0.0
4.152AlaGln: 4.152 ± 0.0
3.114AlaArg: 3.114 ± 0.0
2.768AlaSer: 2.768 ± 0.0
5.19AlaThr: 5.19 ± 0.0
3.114AlaVal: 3.114 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
3.46AlaTyr: 3.46 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.384CysAla: 1.384 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.384CysAsp: 1.384 ± 0.0
0.346CysGlu: 0.346 ± 0.0
0.692CysPhe: 0.692 ± 0.0
1.384CysGly: 1.384 ± 0.0
0.346CysHis: 0.346 ± 0.0
0.692CysIle: 0.692 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.692CysLeu: 0.692 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.692CysAsn: 0.692 ± 0.0
1.038CysPro: 1.038 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.346CysArg: 0.346 ± 0.0
0.692CysSer: 0.692 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.038CysVal: 1.038 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.692CysTyr: 0.692 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.692AspAla: 0.692 ± 0.0
0.346AspCys: 0.346 ± 0.0
3.806AspAsp: 3.806 ± 0.0
2.422AspGlu: 2.422 ± 0.0
4.498AspPhe: 4.498 ± 0.0
2.768AspGly: 2.768 ± 0.0
0.346AspHis: 0.346 ± 0.0
4.498AspIle: 4.498 ± 0.0
2.422AspLys: 2.422 ± 0.0
7.612AspLeu: 7.612 ± 0.0
1.73AspMet: 1.73 ± 0.0
1.73AspAsn: 1.73 ± 0.0
3.114AspPro: 3.114 ± 0.0
1.73AspGln: 1.73 ± 0.0
2.076AspArg: 2.076 ± 0.0
3.806AspSer: 3.806 ± 0.0
1.73AspThr: 1.73 ± 0.0
2.422AspVal: 2.422 ± 0.0
0.346AspTrp: 0.346 ± 0.0
2.422AspTyr: 2.422 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.038GluAla: 1.038 ± 0.0
0.0GluCys: 0.0 ± 0.0
4.498GluAsp: 4.498 ± 0.0
2.076GluGlu: 2.076 ± 0.0
2.422GluPhe: 2.422 ± 0.0
1.73GluGly: 1.73 ± 0.0
1.384GluHis: 1.384 ± 0.0
2.422GluIle: 2.422 ± 0.0
0.692GluLys: 0.692 ± 0.0
3.806GluLeu: 3.806 ± 0.0
2.076GluMet: 2.076 ± 0.0
3.114GluAsn: 3.114 ± 0.0
1.384GluPro: 1.384 ± 0.0
1.73GluGln: 1.73 ± 0.0
2.076GluArg: 2.076 ± 0.0
3.114GluSer: 3.114 ± 0.0
2.422GluThr: 2.422 ± 0.0
4.498GluVal: 4.498 ± 0.0
1.384GluTrp: 1.384 ± 0.0
3.114GluTyr: 3.114 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.73PheAla: 1.73 ± 0.0
0.692PheCys: 0.692 ± 0.0
3.114PheAsp: 3.114 ± 0.0
4.498PheGlu: 4.498 ± 0.0
3.114PhePhe: 3.114 ± 0.0
3.114PheGly: 3.114 ± 0.0
1.038PheHis: 1.038 ± 0.0
4.152PheIle: 4.152 ± 0.0
2.768PheLys: 2.768 ± 0.0
6.92PheLeu: 6.92 ± 0.0
2.422PheMet: 2.422 ± 0.0
2.768PheAsn: 2.768 ± 0.0
1.384PhePro: 1.384 ± 0.0
0.692PheGln: 0.692 ± 0.0
4.498PheArg: 4.498 ± 0.0
6.92PheSer: 6.92 ± 0.0
2.076PheThr: 2.076 ± 0.0
4.498PheVal: 4.498 ± 0.0
1.038PheTrp: 1.038 ± 0.0
2.768PheTyr: 2.768 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.768GlyAla: 2.768 ± 0.0
0.346GlyCys: 0.346 ± 0.0
4.152GlyAsp: 4.152 ± 0.0
2.422GlyGlu: 2.422 ± 0.0
2.076GlyPhe: 2.076 ± 0.0
1.384GlyGly: 1.384 ± 0.0
1.038GlyHis: 1.038 ± 0.0
4.152GlyIle: 4.152 ± 0.0
2.768GlyLys: 2.768 ± 0.0
3.46GlyLeu: 3.46 ± 0.0
1.384GlyMet: 1.384 ± 0.0
4.498GlyAsn: 4.498 ± 0.0
2.768GlyPro: 2.768 ± 0.0
0.346GlyGln: 0.346 ± 0.0
1.038GlyArg: 1.038 ± 0.0
5.536GlySer: 5.536 ± 0.0
4.152GlyThr: 4.152 ± 0.0
5.19GlyVal: 5.19 ± 0.0
1.384GlyTrp: 1.384 ± 0.0
4.498GlyTyr: 4.498 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.768HisAla: 2.768 ± 0.0
0.692HisCys: 0.692 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.73HisGlu: 1.73 ± 0.0
0.692HisPhe: 0.692 ± 0.0
0.346HisGly: 0.346 ± 0.0
0.692HisHis: 0.692 ± 0.0
2.422HisIle: 2.422 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.076HisLeu: 2.076 ± 0.0
0.692HisMet: 0.692 ± 0.0
0.346HisAsn: 0.346 ± 0.0
0.346HisPro: 0.346 ± 0.0
0.346HisGln: 0.346 ± 0.0
1.384HisArg: 1.384 ± 0.0
2.422HisSer: 2.422 ± 0.0
0.692HisThr: 0.692 ± 0.0
1.038HisVal: 1.038 ± 0.0
0.692HisTrp: 0.692 ± 0.0
1.384HisTyr: 1.384 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.46IleAla: 3.46 ± 0.0
1.73IleCys: 1.73 ± 0.0
3.114IleAsp: 3.114 ± 0.0
2.768IleGlu: 2.768 ± 0.0
5.536IlePhe: 5.536 ± 0.0
2.076IleGly: 2.076 ± 0.0
1.73IleHis: 1.73 ± 0.0
3.114IleIle: 3.114 ± 0.0
1.73IleLys: 1.73 ± 0.0
6.228IleLeu: 6.228 ± 0.0
1.038IleMet: 1.038 ± 0.0
1.73IleAsn: 1.73 ± 0.0
2.422IlePro: 2.422 ± 0.0
2.076IleGln: 2.076 ± 0.0
2.768IleArg: 2.768 ± 0.0
8.997IleSer: 8.997 ± 0.0
2.768IleThr: 2.768 ± 0.0
5.19IleVal: 5.19 ± 0.0
1.038IleTrp: 1.038 ± 0.0
1.73IleTyr: 1.73 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.076LysAla: 2.076 ± 0.0
1.038LysCys: 1.038 ± 0.0
0.692LysAsp: 0.692 ± 0.0
2.422LysGlu: 2.422 ± 0.0
2.422LysPhe: 2.422 ± 0.0
1.73LysGly: 1.73 ± 0.0
0.346LysHis: 0.346 ± 0.0
3.114LysIle: 3.114 ± 0.0
4.844LysLys: 4.844 ± 0.0
4.152LysLeu: 4.152 ± 0.0
0.692LysMet: 0.692 ± 0.0
3.114LysAsn: 3.114 ± 0.0
1.384LysPro: 1.384 ± 0.0
2.768LysGln: 2.768 ± 0.0
4.844LysArg: 4.844 ± 0.0
4.844LysSer: 4.844 ± 0.0
2.422LysThr: 2.422 ± 0.0
1.038LysVal: 1.038 ± 0.0
1.038LysTrp: 1.038 ± 0.0
3.114LysTyr: 3.114 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.844LeuAla: 4.844 ± 0.0
0.346LeuCys: 0.346 ± 0.0
4.498LeuAsp: 4.498 ± 0.0
3.46LeuGlu: 3.46 ± 0.0
8.304LeuPhe: 8.304 ± 0.0
4.498LeuGly: 4.498 ± 0.0
2.076LeuHis: 2.076 ± 0.0
4.844LeuIle: 4.844 ± 0.0
5.882LeuLys: 5.882 ± 0.0
6.574LeuLeu: 6.574 ± 0.0
2.768LeuMet: 2.768 ± 0.0
3.46LeuAsn: 3.46 ± 0.0
4.498LeuPro: 4.498 ± 0.0
2.076LeuGln: 2.076 ± 0.0
5.19LeuArg: 5.19 ± 0.0
11.419LeuSer: 11.419 ± 0.0
4.844LeuThr: 4.844 ± 0.0
7.958LeuVal: 7.958 ± 0.0
0.346LeuTrp: 0.346 ± 0.0
3.114LeuTyr: 3.114 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.076MetAla: 2.076 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.384MetAsp: 1.384 ± 0.0
1.038MetGlu: 1.038 ± 0.0
0.692MetPhe: 0.692 ± 0.0
1.038MetGly: 1.038 ± 0.0
0.346MetHis: 0.346 ± 0.0
1.384MetIle: 1.384 ± 0.0
2.076MetLys: 2.076 ± 0.0
2.422MetLeu: 2.422 ± 0.0
1.038MetMet: 1.038 ± 0.0
1.384MetAsn: 1.384 ± 0.0
2.768MetPro: 2.768 ± 0.0
2.076MetGln: 2.076 ± 0.0
0.692MetArg: 0.692 ± 0.0
3.114MetSer: 3.114 ± 0.0
0.692MetThr: 0.692 ± 0.0
1.038MetVal: 1.038 ± 0.0
0.346MetTrp: 0.346 ± 0.0
1.73MetTyr: 1.73 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.46AsnAla: 3.46 ± 0.0
0.346AsnCys: 0.346 ± 0.0
2.076AsnAsp: 2.076 ± 0.0
2.076AsnGlu: 2.076 ± 0.0
1.73AsnPhe: 1.73 ± 0.0
3.114AsnGly: 3.114 ± 0.0
0.692AsnHis: 0.692 ± 0.0
3.806AsnIle: 3.806 ± 0.0
2.422AsnLys: 2.422 ± 0.0
4.498AsnLeu: 4.498 ± 0.0
1.384AsnMet: 1.384 ± 0.0
3.46AsnAsn: 3.46 ± 0.0
4.152AsnPro: 4.152 ± 0.0
1.73AsnGln: 1.73 ± 0.0
0.692AsnArg: 0.692 ± 0.0
5.536AsnSer: 5.536 ± 0.0
2.422AsnThr: 2.422 ± 0.0
7.612AsnVal: 7.612 ± 0.0
0.346AsnTrp: 0.346 ± 0.0
2.422AsnTyr: 2.422 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.076ProAla: 2.076 ± 0.0
0.346ProCys: 0.346 ± 0.0
1.384ProAsp: 1.384 ± 0.0
2.422ProGlu: 2.422 ± 0.0
4.844ProPhe: 4.844 ± 0.0
2.422ProGly: 2.422 ± 0.0
0.346ProHis: 0.346 ± 0.0
2.422ProIle: 2.422 ± 0.0
1.038ProLys: 1.038 ± 0.0
5.882ProLeu: 5.882 ± 0.0
0.692ProMet: 0.692 ± 0.0
1.384ProAsn: 1.384 ± 0.0
3.806ProPro: 3.806 ± 0.0
1.038ProGln: 1.038 ± 0.0
1.038ProArg: 1.038 ± 0.0
3.806ProSer: 3.806 ± 0.0
2.768ProThr: 2.768 ± 0.0
4.152ProVal: 4.152 ± 0.0
1.73ProTrp: 1.73 ± 0.0
2.422ProTyr: 2.422 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.384GlnAla: 1.384 ± 0.0
0.346GlnCys: 0.346 ± 0.0
2.422GlnAsp: 2.422 ± 0.0
2.768GlnGlu: 2.768 ± 0.0
1.73GlnPhe: 1.73 ± 0.0
2.076GlnGly: 2.076 ± 0.0
1.038GlnHis: 1.038 ± 0.0
2.768GlnIle: 2.768 ± 0.0
1.73GlnLys: 1.73 ± 0.0
3.46GlnLeu: 3.46 ± 0.0
1.038GlnMet: 1.038 ± 0.0
0.346GlnAsn: 0.346 ± 0.0
0.346GlnPro: 0.346 ± 0.0
0.692GlnGln: 0.692 ± 0.0
1.73GlnArg: 1.73 ± 0.0
5.19GlnSer: 5.19 ± 0.0
1.384GlnThr: 1.384 ± 0.0
1.73GlnVal: 1.73 ± 0.0
0.692GlnTrp: 0.692 ± 0.0
1.038GlnTyr: 1.038 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.038ArgAla: 1.038 ± 0.0
0.692ArgCys: 0.692 ± 0.0
1.038ArgAsp: 1.038 ± 0.0
1.038ArgGlu: 1.038 ± 0.0
3.114ArgPhe: 3.114 ± 0.0
3.806ArgGly: 3.806 ± 0.0
1.384ArgHis: 1.384 ± 0.0
2.422ArgIle: 2.422 ± 0.0
1.73ArgLys: 1.73 ± 0.0
4.844ArgLeu: 4.844 ± 0.0
2.422ArgMet: 2.422 ± 0.0
3.114ArgAsn: 3.114 ± 0.0
2.768ArgPro: 2.768 ± 0.0
0.0ArgGln: 0.0 ± 0.0
3.114ArgArg: 3.114 ± 0.0
4.844ArgSer: 4.844 ± 0.0
2.768ArgThr: 2.768 ± 0.0
4.152ArgVal: 4.152 ± 0.0
0.692ArgTrp: 0.692 ± 0.0
3.114ArgTyr: 3.114 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
7.266SerAla: 7.266 ± 0.0
1.038SerCys: 1.038 ± 0.0
5.19SerAsp: 5.19 ± 0.0
4.844SerGlu: 4.844 ± 0.0
4.498SerPhe: 4.498 ± 0.0
8.304SerGly: 8.304 ± 0.0
2.076SerHis: 2.076 ± 0.0
4.152SerIle: 4.152 ± 0.0
6.92SerLys: 6.92 ± 0.0
10.035SerLeu: 10.035 ± 0.0
3.46SerMet: 3.46 ± 0.0
5.882SerAsn: 5.882 ± 0.0
2.768SerPro: 2.768 ± 0.0
5.19SerGln: 5.19 ± 0.0
2.422SerArg: 2.422 ± 0.0
8.651SerSer: 8.651 ± 0.0
5.536SerThr: 5.536 ± 0.0
7.266SerVal: 7.266 ± 0.0
1.038SerTrp: 1.038 ± 0.0
3.806SerTyr: 3.806 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.498ThrAla: 4.498 ± 0.0
0.692ThrCys: 0.692 ± 0.0
3.46ThrAsp: 3.46 ± 0.0
0.692ThrGlu: 0.692 ± 0.0
3.114ThrPhe: 3.114 ± 0.0
2.422ThrGly: 2.422 ± 0.0
2.076ThrHis: 2.076 ± 0.0
2.768ThrIle: 2.768 ± 0.0
2.422ThrLys: 2.422 ± 0.0
5.19ThrLeu: 5.19 ± 0.0
0.692ThrMet: 0.692 ± 0.0
2.076ThrAsn: 2.076 ± 0.0
2.422ThrPro: 2.422 ± 0.0
3.114ThrGln: 3.114 ± 0.0
2.768ThrArg: 2.768 ± 0.0
5.536ThrSer: 5.536 ± 0.0
5.19ThrThr: 5.19 ± 0.0
5.19ThrVal: 5.19 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
2.076ThrTyr: 2.076 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.92ValAla: 6.92 ± 0.0
0.692ValCys: 0.692 ± 0.0
2.768ValAsp: 2.768 ± 0.0
2.768ValGlu: 2.768 ± 0.0
3.46ValPhe: 3.46 ± 0.0
4.498ValGly: 4.498 ± 0.0
1.73ValHis: 1.73 ± 0.0
3.806ValIle: 3.806 ± 0.0
3.806ValLys: 3.806 ± 0.0
6.228ValLeu: 6.228 ± 0.0
1.73ValMet: 1.73 ± 0.0
6.228ValAsn: 6.228 ± 0.0
4.844ValPro: 4.844 ± 0.0
1.384ValGln: 1.384 ± 0.0
4.152ValArg: 4.152 ± 0.0
9.343ValSer: 9.343 ± 0.0
3.806ValThr: 3.806 ± 0.0
5.536ValVal: 5.536 ± 0.0
0.346ValTrp: 0.346 ± 0.0
2.768ValTyr: 2.768 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.038TrpCys: 1.038 ± 0.0
1.038TrpAsp: 1.038 ± 0.0
0.346TrpGlu: 0.346 ± 0.0
1.384TrpPhe: 1.384 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.692TrpIle: 0.692 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.692TrpLeu: 0.692 ± 0.0
0.346TrpMet: 0.346 ± 0.0
2.076TrpAsn: 2.076 ± 0.0
0.692TrpPro: 0.692 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.384TrpArg: 1.384 ± 0.0
1.384TrpSer: 1.384 ± 0.0
1.384TrpThr: 1.384 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.346TrpTyr: 0.346 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.038TyrAla: 1.038 ± 0.0
0.692TyrCys: 0.692 ± 0.0
3.114TyrAsp: 3.114 ± 0.0
1.73TyrGlu: 1.73 ± 0.0
3.806TyrPhe: 3.806 ± 0.0
4.152TyrGly: 4.152 ± 0.0
1.384TyrHis: 1.384 ± 0.0
2.768TyrIle: 2.768 ± 0.0
1.384TyrLys: 1.384 ± 0.0
3.46TyrLeu: 3.46 ± 0.0
1.038TyrMet: 1.038 ± 0.0
2.768TyrAsn: 2.768 ± 0.0
1.73TyrPro: 1.73 ± 0.0
2.768TyrGln: 2.768 ± 0.0
2.768TyrArg: 2.768 ± 0.0
2.768TyrSer: 2.768 ± 0.0
4.152TyrThr: 4.152 ± 0.0
4.152TyrVal: 4.152 ± 0.0
0.346TyrTrp: 0.346 ± 0.0
1.038TyrTyr: 1.038 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2891 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski