Amino acid dipepetide frequency for Phytophthora parasitica P10297

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.303AlaAla: 9.303 ± 0.043	1.282AlaCys: 1.282 ± 0.012	4.227AlaAsp: 4.227 ± 0.022	5.263AlaGlu: 5.263 ± 0.028	3.154AlaPhe: 3.154 ± 0.019	4.627AlaGly: 4.627 ± 0.024	1.697AlaHis: 1.697 ± 0.014	3.799AlaIle: 3.799 ± 0.017	4.585AlaLys: 4.585 ± 0.024	8.378AlaLeu: 8.378 ± 0.035	2.241AlaMet: 2.241 ± 0.016	3.025AlaAsn: 3.025 ± 0.018	4.001AlaPro: 4.001 ± 0.029	3.453AlaGln: 3.453 ± 0.023	4.911AlaArg: 4.911 ± 0.027	7.467AlaSer: 7.467 ± 0.031	5.635AlaThr: 5.635 ± 0.029	6.174AlaVal: 6.174 ± 0.026	0.89AlaTrp: 0.89 ± 0.009	1.873AlaTyr: 1.873 ± 0.014	0.0AlaXaa: 0.0 ± 0.0
Cys	1.27CysAla: 1.27 ± 0.012	0.456CysCys: 0.456 ± 0.007	0.854CysAsp: 0.854 ± 0.011	0.937CysGlu: 0.937 ± 0.01	0.702CysPhe: 0.702 ± 0.009	1.227CysGly: 1.227 ± 0.013	0.399CysHis: 0.399 ± 0.006	0.804CysIle: 0.804 ± 0.009	0.724CysLys: 0.724 ± 0.01	1.422CysLeu: 1.422 ± 0.013	0.409CysMet: 0.409 ± 0.006	0.548CysAsn: 0.548 ± 0.007	0.767CysPro: 0.767 ± 0.016	0.57CysGln: 0.57 ± 0.007	1.042CysArg: 1.042 ± 0.01	1.484CysSer: 1.484 ± 0.014	0.985CysThr: 0.985 ± 0.011	1.276CysVal: 1.276 ± 0.013	0.241CysTrp: 0.241 ± 0.006	0.473CysTyr: 0.473 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.107AspAla: 5.107 ± 0.024	0.825AspCys: 0.825 ± 0.01	4.411AspAsp: 4.411 ± 0.028	4.933AspGlu: 4.933 ± 0.029	2.175AspPhe: 2.175 ± 0.014	3.833AspGly: 3.833 ± 0.023	1.127AspHis: 1.127 ± 0.009	2.586AspIle: 2.586 ± 0.015	2.552AspLys: 2.552 ± 0.018	4.766AspLeu: 4.766 ± 0.022	1.313AspMet: 1.313 ± 0.012	1.999AspAsn: 1.999 ± 0.015	2.525AspPro: 2.525 ± 0.016	1.924AspGln: 1.924 ± 0.015	2.83AspArg: 2.83 ± 0.017	4.315AspSer: 4.315 ± 0.025	3.107AspThr: 3.107 ± 0.019	4.323AspVal: 4.323 ± 0.018	0.631AspTrp: 0.631 ± 0.008	1.438AspTyr: 1.438 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	5.76GluAla: 5.76 ± 0.031	0.932GluCys: 0.932 ± 0.01	4.34GluAsp: 4.34 ± 0.026	6.076GluGlu: 6.076 ± 0.041	2.261GluPhe: 2.261 ± 0.015	3.212GluGly: 3.212 ± 0.021	1.493GluHis: 1.493 ± 0.014	3.058GluIle: 3.058 ± 0.017	3.974GluLys: 3.974 ± 0.023	6.741GluLeu: 6.741 ± 0.035	1.822GluMet: 1.822 ± 0.013	2.638GluAsn: 2.638 ± 0.017	2.292GluPro: 2.292 ± 0.019	3.024GluGln: 3.024 ± 0.023	4.315GluArg: 4.315 ± 0.026	4.558GluSer: 4.558 ± 0.025	3.663GluThr: 3.663 ± 0.024	4.136GluVal: 4.136 ± 0.021	0.765GluTrp: 0.765 ± 0.01	1.689GluTyr: 1.689 ± 0.013	0.0GluXaa: 0.0 ± 0.0
Phe	3.063PheAla: 3.063 ± 0.018	0.736PheCys: 0.736 ± 0.009	2.276PheAsp: 2.276 ± 0.017	2.275PheGlu: 2.275 ± 0.015	1.655PhePhe: 1.655 ± 0.015	2.67PheGly: 2.67 ± 0.019	0.947PheHis: 0.947 ± 0.009	1.578PheIle: 1.578 ± 0.015	1.549PheLys: 1.549 ± 0.013	3.526PheLeu: 3.526 ± 0.023	0.928PheMet: 0.928 ± 0.01	1.338PheAsn: 1.338 ± 0.012	1.636PhePro: 1.636 ± 0.01	1.527PheGln: 1.527 ± 0.013	2.13PheArg: 2.13 ± 0.01	3.012PheSer: 3.012 ± 0.017	2.104PheThr: 2.104 ± 0.016	2.902PheVal: 2.902 ± 0.019	0.456PheTrp: 0.456 ± 0.008	1.177PheTyr: 1.177 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	4.743GlyAla: 4.743 ± 0.026	1.06GlyCys: 1.06 ± 0.013	3.683GlyAsp: 3.683 ± 0.022	3.52GlyGlu: 3.52 ± 0.017	2.366GlyPhe: 2.366 ± 0.018	4.587GlyGly: 4.587 ± 0.043	1.427GlyHis: 1.427 ± 0.015	2.776GlyIle: 2.776 ± 0.017	3.132GlyLys: 3.132 ± 0.02	4.726GlyLeu: 4.726 ± 0.025	1.439GlyMet: 1.439 ± 0.014	2.398GlyAsn: 2.398 ± 0.019	1.952GlyPro: 1.952 ± 0.015	1.95GlyGln: 1.95 ± 0.016	3.404GlyArg: 3.404 ± 0.021	5.295GlySer: 5.295 ± 0.033	3.313GlyThr: 3.313 ± 0.025	4.334GlyVal: 4.334 ± 0.024	0.757GlyTrp: 0.757 ± 0.009	1.79GlyTyr: 1.79 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	1.842HisAla: 1.842 ± 0.014	0.447HisCys: 0.447 ± 0.007	1.281HisAsp: 1.281 ± 0.011	1.502HisGlu: 1.502 ± 0.013	0.999HisPhe: 0.999 ± 0.009	1.533HisGly: 1.533 ± 0.014	0.736HisHis: 0.736 ± 0.009	0.974HisIle: 0.974 ± 0.011	1.014HisLys: 1.014 ± 0.011	2.232HisLeu: 2.232 ± 0.016	0.495HisMet: 0.495 ± 0.007	0.774HisAsn: 0.774 ± 0.007	1.212HisPro: 1.212 ± 0.011	1.027HisGln: 1.027 ± 0.011	1.607HisArg: 1.607 ± 0.012	1.802HisSer: 1.802 ± 0.015	1.179HisThr: 1.179 ± 0.011	1.718HisVal: 1.718 ± 0.013	0.301HisTrp: 0.301 ± 0.005	0.688HisTyr: 0.688 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	3.823IleAla: 3.823 ± 0.019	0.841IleCys: 0.841 ± 0.009	2.559IleAsp: 2.559 ± 0.017	2.748IleGlu: 2.748 ± 0.017	1.66IlePhe: 1.66 ± 0.016	2.509IleGly: 2.509 ± 0.018	0.99IleHis: 0.99 ± 0.01	1.817IleIle: 1.817 ± 0.016	2.058IleLys: 2.058 ± 0.014	3.797IleLeu: 3.797 ± 0.022	0.968IleMet: 0.968 ± 0.008	1.522IleAsn: 1.522 ± 0.014	2.226IlePro: 2.226 ± 0.013	1.818IleGln: 1.818 ± 0.014	2.598IleArg: 2.598 ± 0.016	3.378IleSer: 3.378 ± 0.021	2.461IleThr: 2.461 ± 0.015	3.234IleVal: 3.234 ± 0.02	0.504IleTrp: 0.504 ± 0.007	1.154IleTyr: 1.154 ± 0.011	0.0IleXaa: 0.0 ± 0.0
Lys	4.087LysAla: 4.087 ± 0.023	0.781LysCys: 0.781 ± 0.008	2.524LysAsp: 2.524 ± 0.015	3.568LysGlu: 3.568 ± 0.021	1.678LysPhe: 1.678 ± 0.013	2.332LysGly: 2.332 ± 0.016	1.262LysHis: 1.262 ± 0.009	2.216LysIle: 2.216 ± 0.015	4.136LysLys: 4.136 ± 0.036	5.19LysLeu: 5.19 ± 0.022	1.406LysMet: 1.406 ± 0.013	2.009LysAsn: 2.009 ± 0.015	2.312LysPro: 2.312 ± 0.017	2.477LysGln: 2.477 ± 0.017	4.009LysArg: 4.009 ± 0.022	3.644LysSer: 3.644 ± 0.02	3.285LysThr: 3.285 ± 0.022	3.026LysVal: 3.026 ± 0.019	0.729LysTrp: 0.729 ± 0.009	1.501LysTyr: 1.501 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	7.916LeuAla: 7.916 ± 0.033	1.62LeuCys: 1.62 ± 0.015	5.107LeuAsp: 5.107 ± 0.025	6.505LeuGlu: 6.505 ± 0.037	3.475LeuPhe: 3.475 ± 0.02	4.896LeuGly: 4.896 ± 0.025	2.579LeuHis: 2.579 ± 0.017	3.362LeuIle: 3.362 ± 0.019	4.81LeuLys: 4.81 ± 0.025	10.005LeuLeu: 10.005 ± 0.055	2.182LeuMet: 2.182 ± 0.016	3.263LeuAsn: 3.263 ± 0.018	4.619LeuPro: 4.619 ± 0.024	4.899LeuGln: 4.899 ± 0.029	6.494LeuArg: 6.494 ± 0.032	7.404LeuSer: 7.404 ± 0.031	5.005LeuThr: 5.005 ± 0.028	6.515LeuVal: 6.515 ± 0.029	1.071LeuTrp: 1.071 ± 0.012	2.306LeuTyr: 2.306 ± 0.016	0.0LeuXaa: 0.0 ± 0.0
Met	2.188MetAla: 2.188 ± 0.015	0.369MetCys: 0.369 ± 0.006	1.449MetAsp: 1.449 ± 0.014	1.844MetGlu: 1.844 ± 0.013	0.798MetPhe: 0.798 ± 0.009	1.323MetGly: 1.323 ± 0.012	0.574MetHis: 0.574 ± 0.007	0.974MetIle: 0.974 ± 0.009	1.423MetLys: 1.423 ± 0.012	2.47MetLeu: 2.47 ± 0.017	0.704MetMet: 0.704 ± 0.009	0.949MetAsn: 0.949 ± 0.01	1.092MetPro: 1.092 ± 0.011	1.158MetGln: 1.158 ± 0.012	1.497MetArg: 1.497 ± 0.012	1.838MetSer: 1.838 ± 0.014	1.487MetThr: 1.487 ± 0.012	1.53MetVal: 1.53 ± 0.014	0.299MetTrp: 0.299 ± 0.005	0.629MetTyr: 0.629 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.432AsnAla: 3.432 ± 0.018	0.638AsnCys: 0.638 ± 0.008	2.146AsnAsp: 2.146 ± 0.015	2.441AsnGlu: 2.441 ± 0.018	1.344AsnPhe: 1.344 ± 0.011	2.802AsnGly: 2.802 ± 0.017	0.795AsnHis: 0.795 ± 0.009	1.558AsnIle: 1.558 ± 0.012	1.697AsnLys: 1.697 ± 0.014	3.048AsnLeu: 3.048 ± 0.019	0.893AsnMet: 0.893 ± 0.01	1.481AsnAsn: 1.481 ± 0.015	1.805AsnPro: 1.805 ± 0.014	1.416AsnGln: 1.416 ± 0.012	2.008AsnArg: 2.008 ± 0.015	2.958AsnSer: 2.958 ± 0.02	2.15AsnThr: 2.15 ± 0.014	2.708AsnVal: 2.708 ± 0.016	0.445AsnTrp: 0.445 ± 0.007	0.992AsnTyr: 0.992 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	4.036ProAla: 4.036 ± 0.027	0.565ProCys: 0.565 ± 0.008	2.392ProAsp: 2.392 ± 0.015	2.967ProGlu: 2.967 ± 0.019	1.642ProPhe: 1.642 ± 0.013	2.489ProGly: 2.489 ± 0.019	1.026ProHis: 1.026 ± 0.009	1.822ProIle: 1.822 ± 0.015	2.237ProLys: 2.237 ± 0.017	3.992ProLeu: 3.992 ± 0.02	1.082ProMet: 1.082 ± 0.011	1.647ProAsn: 1.647 ± 0.013	3.274ProPro: 3.274 ± 0.03	1.821ProGln: 1.821 ± 0.015	2.834ProArg: 2.834 ± 0.02	4.53ProSer: 4.53 ± 0.025	3.432ProThr: 3.432 ± 0.024	3.411ProVal: 3.411 ± 0.023	0.489ProTrp: 0.489 ± 0.007	1.026ProTyr: 1.026 ± 0.011	0.0ProXaa: 0.0 ± 0.0
Gln	3.282GlnAla: 3.282 ± 0.017	0.639GlnCys: 0.639 ± 0.008	2.025GlnAsp: 2.025 ± 0.014	2.899GlnGlu: 2.899 ± 0.021	1.467GlnPhe: 1.467 ± 0.012	1.843GlnGly: 1.843 ± 0.016	1.217GlnHis: 1.217 ± 0.01	1.812GlnIle: 1.812 ± 0.013	2.179GlnLys: 2.179 ± 0.016	4.674GlnLeu: 4.674 ± 0.026	1.09GlnMet: 1.09 ± 0.011	1.463GlnAsn: 1.463 ± 0.012	1.853GlnPro: 1.853 ± 0.015	3.112GlnGln: 3.112 ± 0.035	3.319GlnArg: 3.319 ± 0.025	2.976GlnSer: 2.976 ± 0.017	2.373GlnThr: 2.373 ± 0.015	2.711GlnVal: 2.711 ± 0.016	0.591GlnTrp: 0.591 ± 0.009	1.122GlnTyr: 1.122 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	4.865ArgAla: 4.865 ± 0.024	1.073ArgCys: 1.073 ± 0.011	3.24ArgAsp: 3.24 ± 0.023	4.102ArgGlu: 4.102 ± 0.025	2.417ArgPhe: 2.417 ± 0.016	3.512ArgGly: 3.512 ± 0.021	1.65ArgHis: 1.65 ± 0.014	2.671ArgIle: 2.671 ± 0.017	3.655ArgLys: 3.655 ± 0.022	5.952ArgLeu: 5.952 ± 0.029	1.513ArgMet: 1.513 ± 0.012	2.25ArgAsn: 2.25 ± 0.016	2.528ArgPro: 2.528 ± 0.018	2.995ArgGln: 2.995 ± 0.021	5.578ArgArg: 5.578 ± 0.037	5.243ArgSer: 5.243 ± 0.027	3.189ArgThr: 3.189 ± 0.017	4.335ArgVal: 4.335 ± 0.02	0.878ArgTrp: 0.878 ± 0.009	1.671ArgTyr: 1.671 ± 0.012	0.0ArgXaa: 0.0 ± 0.0
Ser	6.796SerAla: 6.796 ± 0.028	1.307SerCys: 1.307 ± 0.011	4.737SerAsp: 4.737 ± 0.026	4.613SerGlu: 4.613 ± 0.026	3.116SerPhe: 3.116 ± 0.019	5.348SerGly: 5.348 ± 0.031	1.627SerHis: 1.627 ± 0.013	3.615SerIle: 3.615 ± 0.021	4.012SerLys: 4.012 ± 0.023	7.004SerLeu: 7.004 ± 0.032	1.953SerMet: 1.953 ± 0.015	3.167SerAsn: 3.167 ± 0.017	4.34SerPro: 4.34 ± 0.025	2.79SerGln: 2.79 ± 0.017	4.875SerArg: 4.875 ± 0.026	9.919SerSer: 9.919 ± 0.057	5.945SerThr: 5.945 ± 0.032	5.516SerVal: 5.516 ± 0.026	0.97SerTrp: 0.97 ± 0.01	1.942SerTyr: 1.942 ± 0.017	0.0SerXaa: 0.0 ± 0.0
Thr	5.279ThrAla: 5.279 ± 0.027	0.968ThrCys: 0.968 ± 0.011	2.949ThrAsp: 2.949 ± 0.019	3.489ThrGlu: 3.489 ± 0.02	2.118ThrPhe: 2.118 ± 0.017	3.653ThrGly: 3.653 ± 0.026	1.25ThrHis: 1.25 ± 0.012	2.68ThrIle: 2.68 ± 0.022	3.072ThrLys: 3.072 ± 0.018	5.471ThrLeu: 5.471 ± 0.027	1.405ThrMet: 1.405 ± 0.013	2.176ThrAsn: 2.176 ± 0.018	3.646ThrPro: 3.646 ± 0.028	2.352ThrGln: 2.352 ± 0.016	3.424ThrArg: 3.424 ± 0.019	5.584ThrSer: 5.584 ± 0.031	4.452ThrThr: 4.452 ± 0.037	3.894ThrVal: 3.894 ± 0.024	0.701ThrTrp: 0.701 ± 0.01	1.401ThrTyr: 1.401 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	6.392ValAla: 6.392 ± 0.026	1.273ValCys: 1.273 ± 0.012	4.29ValAsp: 4.29 ± 0.021	4.74ValGlu: 4.74 ± 0.023	2.788ValPhe: 2.788 ± 0.018	3.849ValGly: 3.849 ± 0.022	1.611ValHis: 1.611 ± 0.014	2.894ValIle: 2.894 ± 0.017	3.454ValLys: 3.454 ± 0.02	6.883ValLeu: 6.883 ± 0.034	1.682ValMet: 1.682 ± 0.013	2.546ValAsn: 2.546 ± 0.017	3.134ValPro: 3.134 ± 0.019	2.818ValGln: 2.818 ± 0.018	3.94ValArg: 3.94 ± 0.019	5.339ValSer: 5.339 ± 0.026	4.03ValThr: 4.03 ± 0.031	5.612ValVal: 5.612 ± 0.028	0.795ValTrp: 0.795 ± 0.008	1.874ValTyr: 1.874 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	0.714TrpAla: 0.714 ± 0.008	0.223TrpCys: 0.223 ± 0.005	0.667TrpAsp: 0.667 ± 0.008	0.687TrpGlu: 0.687 ± 0.008	0.481TrpPhe: 0.481 ± 0.008	0.659TrpGly: 0.659 ± 0.009	0.289TrpHis: 0.289 ± 0.005	0.609TrpIle: 0.609 ± 0.008	0.794TrpLys: 0.794 ± 0.009	1.249TrpLeu: 1.249 ± 0.013	0.409TrpMet: 0.409 ± 0.006	0.552TrpAsn: 0.552 ± 0.008	0.391TrpPro: 0.391 ± 0.006	0.497TrpGln: 0.497 ± 0.006	0.871TrpArg: 0.871 ± 0.01	0.93TrpSer: 0.93 ± 0.009	0.761TrpThr: 0.761 ± 0.008	0.726TrpVal: 0.726 ± 0.008	0.189TrpTrp: 0.189 ± 0.004	0.37TrpTyr: 0.37 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.087TyrAla: 2.087 ± 0.014	0.555TyrCys: 0.555 ± 0.009	1.562TyrAsp: 1.562 ± 0.014	1.639TyrGlu: 1.639 ± 0.012	1.19TyrPhe: 1.19 ± 0.011	1.747TyrGly: 1.747 ± 0.015	0.67TyrHis: 0.67 ± 0.007	1.065TyrIle: 1.065 ± 0.012	1.115TyrLys: 1.115 ± 0.012	2.506TyrLeu: 2.506 ± 0.016	0.658TyrMet: 0.658 ± 0.007	1.008TyrAsn: 1.008 ± 0.011	1.108TyrPro: 1.108 ± 0.011	1.02TyrGln: 1.02 ± 0.011	1.633TyrArg: 1.633 ± 0.013	1.918TyrSer: 1.918 ± 0.016	1.407TyrThr: 1.407 ± 0.014	1.864TyrVal: 1.864 ± 0.013	0.365TyrTrp: 0.365 ± 0.007	0.867TyrTyr: 0.867 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 26452 proteins (10870524 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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