Amino acid dipepetide frequency for Sutterella parvirubra YIT 11816

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.654AlaAla: 17.654 ± 0.263	1.243AlaCys: 1.243 ± 0.049	6.822AlaAsp: 6.822 ± 0.113	8.799AlaGlu: 8.799 ± 0.166	4.674AlaPhe: 4.674 ± 0.084	10.148AlaGly: 10.148 ± 0.15	2.183AlaHis: 2.183 ± 0.059	4.326AlaIle: 4.326 ± 0.086	5.636AlaLys: 5.636 ± 0.112	12.379AlaLeu: 12.379 ± 0.166	3.365AlaMet: 3.365 ± 0.081	2.64AlaAsn: 2.64 ± 0.064	5.593AlaPro: 5.593 ± 0.135	3.634AlaGln: 3.634 ± 0.074	7.627AlaArg: 7.627 ± 0.114	5.894AlaSer: 5.894 ± 0.097	4.826AlaThr: 4.826 ± 0.085	10.011AlaVal: 10.011 ± 0.136	1.696AlaTrp: 1.696 ± 0.05	2.285AlaTyr: 2.285 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	1.397CysAla: 1.397 ± 0.047	0.186CysCys: 0.186 ± 0.018	0.533CysAsp: 0.533 ± 0.03	0.584CysGlu: 0.584 ± 0.027	0.385CysPhe: 0.385 ± 0.026	1.365CysGly: 1.365 ± 0.057	0.281CysHis: 0.281 ± 0.027	0.314CysIle: 0.314 ± 0.021	0.199CysLys: 0.199 ± 0.019	0.831CysLeu: 0.831 ± 0.037	0.226CysMet: 0.226 ± 0.017	0.239CysAsn: 0.239 ± 0.019	0.659CysPro: 0.659 ± 0.037	0.199CysGln: 0.199 ± 0.017	0.934CysArg: 0.934 ± 0.044	0.533CysSer: 0.533 ± 0.025	0.468CysThr: 0.468 ± 0.029	0.801CysVal: 0.801 ± 0.035	0.155CysTrp: 0.155 ± 0.015	0.235CysTyr: 0.235 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	7.67AspAla: 7.67 ± 0.109	0.537AspCys: 0.537 ± 0.031	3.177AspAsp: 3.177 ± 0.093	4.31AspGlu: 4.31 ± 0.1	2.435AspPhe: 2.435 ± 0.058	4.387AspGly: 4.387 ± 0.098	0.943AspHis: 0.943 ± 0.045	2.17AspIle: 2.17 ± 0.066	1.576AspLys: 1.576 ± 0.05	5.075AspLeu: 5.075 ± 0.088	1.402AspMet: 1.402 ± 0.046	1.053AspAsn: 1.053 ± 0.044	3.468AspPro: 3.468 ± 0.072	1.255AspGln: 1.255 ± 0.046	3.661AspArg: 3.661 ± 0.088	1.674AspSer: 1.674 ± 0.062	2.196AspThr: 2.196 ± 0.059	4.687AspVal: 4.687 ± 0.093	0.928AspTrp: 0.928 ± 0.046	1.328AspTyr: 1.328 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	9.782GluAla: 9.782 ± 0.187	0.584GluCys: 0.584 ± 0.032	3.706GluAsp: 3.706 ± 0.093	4.884GluGlu: 4.884 ± 0.124	1.778GluPhe: 1.778 ± 0.052	5.77GluGly: 5.77 ± 0.105	1.388GluHis: 1.388 ± 0.039	3.045GluIle: 3.045 ± 0.074	3.817GluLys: 3.817 ± 0.103	6.02GluLeu: 6.02 ± 0.106	1.617GluMet: 1.617 ± 0.043	1.988GluAsn: 1.988 ± 0.055	2.995GluPro: 2.995 ± 0.069	1.593GluGln: 1.593 ± 0.052	5.49GluArg: 5.49 ± 0.113	3.002GluSer: 3.002 ± 0.068	3.983GluThr: 3.983 ± 0.086	4.7GluVal: 4.7 ± 0.09	0.699GluTrp: 0.699 ± 0.032	1.083GluTyr: 1.083 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	4.243PheAla: 4.243 ± 0.078	0.474PheCys: 0.474 ± 0.028	2.462PheAsp: 2.462 ± 0.063	2.666PheGlu: 2.666 ± 0.067	1.735PhePhe: 1.735 ± 0.055	3.813PheGly: 3.813 ± 0.079	0.593PheHis: 0.593 ± 0.03	1.769PheIle: 1.769 ± 0.046	1.134PheLys: 1.134 ± 0.041	3.551PheLeu: 3.551 ± 0.087	1.023PheMet: 1.023 ± 0.042	1.054PheAsn: 1.054 ± 0.043	1.758PhePro: 1.758 ± 0.052	0.917PheGln: 0.917 ± 0.04	2.422PheArg: 2.422 ± 0.058	2.322PheSer: 2.322 ± 0.06	2.323PheThr: 2.323 ± 0.061	2.972PheVal: 2.972 ± 0.066	0.6PheTrp: 0.6 ± 0.03	0.888PheTyr: 0.888 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	8.773GlyAla: 8.773 ± 0.11	1.142GlyCys: 1.142 ± 0.049	4.105GlyAsp: 4.105 ± 0.089	5.134GlyGlu: 5.134 ± 0.089	3.794GlyPhe: 3.794 ± 0.085	6.324GlyGly: 6.324 ± 0.124	1.537GlyHis: 1.537 ± 0.051	4.432GlyIle: 4.432 ± 0.073	3.488GlyLys: 3.488 ± 0.085	8.432GlyLeu: 8.432 ± 0.128	2.551GlyMet: 2.551 ± 0.066	2.141GlyAsn: 2.141 ± 0.064	2.892GlyPro: 2.892 ± 0.072	1.838GlyGln: 1.838 ± 0.054	6.492GlyArg: 6.492 ± 0.109	4.198GlySer: 4.198 ± 0.094	4.902GlyThr: 4.902 ± 0.1	6.928GlyVal: 6.928 ± 0.125	1.379GlyTrp: 1.379 ± 0.055	1.935GlyTyr: 1.935 ± 0.061	0.0GlyXaa: 0.0 ± 0.0
His	2.26HisAla: 2.26 ± 0.061	0.255HisCys: 0.255 ± 0.024	1.03HisAsp: 1.03 ± 0.041	1.132HisGlu: 1.132 ± 0.041	0.791HisPhe: 0.791 ± 0.036	1.553HisGly: 1.553 ± 0.049	0.553HisHis: 0.553 ± 0.068	0.785HisIle: 0.785 ± 0.031	0.537HisLys: 0.537 ± 0.025	1.795HisLeu: 1.795 ± 0.051	0.425HisMet: 0.425 ± 0.027	0.415HisAsn: 0.415 ± 0.026	1.421HisPro: 1.421 ± 0.048	0.52HisGln: 0.52 ± 0.027	1.326HisArg: 1.326 ± 0.042	0.785HisSer: 0.785 ± 0.035	0.9HisThr: 0.9 ± 0.043	1.387HisVal: 1.387 ± 0.04	0.308HisTrp: 0.308 ± 0.023	0.524HisTyr: 0.524 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.251IleAla: 5.251 ± 0.106	0.501IleCys: 0.501 ± 0.033	2.84IleAsp: 2.84 ± 0.068	3.472IleGlu: 3.472 ± 0.08	1.664IlePhe: 1.664 ± 0.054	3.737IleGly: 3.737 ± 0.08	0.834IleHis: 0.834 ± 0.035	1.855IleIle: 1.855 ± 0.058	1.381IleLys: 1.381 ± 0.047	4.495IleLeu: 4.495 ± 0.105	0.894IleMet: 0.894 ± 0.038	1.328IleAsn: 1.328 ± 0.038	2.541IlePro: 2.541 ± 0.058	0.973IleGln: 0.973 ± 0.041	3.458IleArg: 3.458 ± 0.072	2.253IleSer: 2.253 ± 0.054	2.429IleThr: 2.429 ± 0.06	3.698IleVal: 3.698 ± 0.078	0.483IleTrp: 0.483 ± 0.028	1.007IleTyr: 1.007 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	5.255LysAla: 5.255 ± 0.122	0.329LysCys: 0.329 ± 0.02	2.326LysAsp: 2.326 ± 0.066	2.312LysGlu: 2.312 ± 0.066	1.083LysPhe: 1.083 ± 0.04	3.264LysGly: 3.264 ± 0.077	0.748LysHis: 0.748 ± 0.037	1.846LysIle: 1.846 ± 0.054	2.435LysLys: 2.435 ± 0.072	3.959LysLeu: 3.959 ± 0.075	1.129LysMet: 1.129 ± 0.039	1.5LysAsn: 1.5 ± 0.047	2.461LysPro: 2.461 ± 0.067	0.839LysGln: 0.839 ± 0.036	2.985LysArg: 2.985 ± 0.075	2.293LysSer: 2.293 ± 0.06	3.117LysThr: 3.117 ± 0.067	2.749LysVal: 2.749 ± 0.072	0.4LysTrp: 0.4 ± 0.026	0.758LysTyr: 0.758 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	11.352LeuAla: 11.352 ± 0.168	1.011LeuCys: 1.011 ± 0.038	4.844LeuAsp: 4.844 ± 0.092	6.345LeuGlu: 6.345 ± 0.118	3.569LeuPhe: 3.569 ± 0.074	7.725LeuGly: 7.725 ± 0.123	1.699LeuHis: 1.699 ± 0.055	4.439LeuIle: 4.439 ± 0.104	4.144LeuLys: 4.144 ± 0.079	8.984LeuLeu: 8.984 ± 0.169	2.611LeuMet: 2.611 ± 0.067	2.504LeuAsn: 2.504 ± 0.059	5.585LeuPro: 5.585 ± 0.099	2.515LeuGln: 2.515 ± 0.07	7.139LeuArg: 7.139 ± 0.123	5.91LeuSer: 5.91 ± 0.087	6.347LeuThr: 6.347 ± 0.113	6.771LeuVal: 6.771 ± 0.117	1.362LeuTrp: 1.362 ± 0.055	1.925LeuTyr: 1.925 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.656MetAla: 2.656 ± 0.071	0.232MetCys: 0.232 ± 0.02	1.149MetAsp: 1.149 ± 0.039	1.427MetGlu: 1.427 ± 0.044	0.71MetPhe: 0.71 ± 0.034	2.134MetGly: 2.134 ± 0.059	0.529MetHis: 0.529 ± 0.029	1.275MetIle: 1.275 ± 0.048	1.424MetLys: 1.424 ± 0.044	2.71MetLeu: 2.71 ± 0.064	0.775MetMet: 0.775 ± 0.037	0.971MetAsn: 0.971 ± 0.038	1.568MetPro: 1.568 ± 0.047	0.765MetGln: 0.765 ± 0.031	2.21MetArg: 2.21 ± 0.062	1.652MetSer: 1.652 ± 0.047	2.322MetThr: 2.322 ± 0.063	1.706MetVal: 1.706 ± 0.05	0.178MetTrp: 0.178 ± 0.016	0.319MetTyr: 0.319 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.309AsnAla: 3.309 ± 0.083	0.274AsnCys: 0.274 ± 0.022	1.465AsnAsp: 1.465 ± 0.046	1.498AsnGlu: 1.498 ± 0.047	1.017AsnPhe: 1.017 ± 0.031	2.197AsnGly: 2.197 ± 0.063	0.533AsnHis: 0.533 ± 0.03	1.223AsnIle: 1.223 ± 0.045	0.845AsnLys: 0.845 ± 0.039	2.767AsnLeu: 2.767 ± 0.076	0.584AsnMet: 0.584 ± 0.027	0.616AsnAsn: 0.616 ± 0.031	2.037AsnPro: 2.037 ± 0.058	0.708AsnGln: 0.708 ± 0.035	1.823AsnArg: 1.823 ± 0.054	0.981AsnSer: 0.981 ± 0.042	1.438AsnThr: 1.438 ± 0.05	2.169AsnVal: 2.169 ± 0.065	0.331AsnTrp: 0.331 ± 0.026	0.643AsnTyr: 0.643 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	6.123ProAla: 6.123 ± 0.119	0.441ProCys: 0.441 ± 0.025	3.18ProAsp: 3.18 ± 0.076	5.152ProGlu: 5.152 ± 0.089	2.097ProPhe: 2.097 ± 0.054	4.266ProGly: 4.266 ± 0.094	1.004ProHis: 1.004 ± 0.04	2.037ProIle: 2.037 ± 0.058	2.6ProLys: 2.6 ± 0.067	4.155ProLeu: 4.155 ± 0.087	1.348ProMet: 1.348 ± 0.042	1.431ProAsn: 1.431 ± 0.048	1.882ProPro: 1.882 ± 0.057	1.586ProGln: 1.586 ± 0.053	2.643ProArg: 2.643 ± 0.059	2.6ProSer: 2.6 ± 0.061	2.716ProThr: 2.716 ± 0.063	4.657ProVal: 4.657 ± 0.082	0.699ProTrp: 0.699 ± 0.035	1.189ProTyr: 1.189 ± 0.043	0.0ProXaa: 0.0 ± 0.0
Gln	2.936GlnAla: 2.936 ± 0.08	0.223GlnCys: 0.223 ± 0.02	1.079GlnAsp: 1.079 ± 0.042	1.441GlnGlu: 1.441 ± 0.051	0.841GlnPhe: 0.841 ± 0.035	1.882GlnGly: 1.882 ± 0.054	0.507GlnHis: 0.507 ± 0.03	1.331GlnIle: 1.331 ± 0.044	1.472GlnLys: 1.472 ± 0.054	2.305GlnLeu: 2.305 ± 0.07	0.778GlnMet: 0.778 ± 0.036	0.834GlnAsn: 0.834 ± 0.039	1.313GlnPro: 1.313 ± 0.048	0.761GlnGln: 0.761 ± 0.04	1.71GlnArg: 1.71 ± 0.052	1.388GlnSer: 1.388 ± 0.044	1.676GlnThr: 1.676 ± 0.053	1.848GlnVal: 1.848 ± 0.056	0.317GlnTrp: 0.317 ± 0.022	0.636GlnTyr: 0.636 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	8.037ArgAla: 8.037 ± 0.123	0.716ArgCys: 0.716 ± 0.033	3.246ArgAsp: 3.246 ± 0.073	5.179ArgGlu: 5.179 ± 0.115	3.173ArgPhe: 3.173 ± 0.065	4.807ArgGly: 4.807 ± 0.085	1.508ArgHis: 1.508 ± 0.055	3.925ArgIle: 3.925 ± 0.079	2.411ArgLys: 2.411 ± 0.056	6.96ArgLeu: 6.96 ± 0.114	2.174ArgMet: 2.174 ± 0.058	1.772ArgAsn: 1.772 ± 0.053	3.6ArgPro: 3.6 ± 0.082	2.017ArgGln: 2.017 ± 0.052	6.791ArgArg: 6.791 ± 0.147	3.498ArgSer: 3.498 ± 0.08	4.323ArgThr: 4.323 ± 0.088	4.88ArgVal: 4.88 ± 0.093	1.218ArgTrp: 1.218 ± 0.046	1.551ArgTyr: 1.551 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	6.152SerAla: 6.152 ± 0.109	0.527SerCys: 0.527 ± 0.028	2.568SerAsp: 2.568 ± 0.068	2.925SerGlu: 2.925 ± 0.075	2.103SerPhe: 2.103 ± 0.059	5.061SerGly: 5.061 ± 0.091	0.887SerHis: 0.887 ± 0.033	2.535SerIle: 2.535 ± 0.063	1.785SerLys: 1.785 ± 0.054	4.74SerLeu: 4.74 ± 0.09	1.379SerMet: 1.379 ± 0.046	1.311SerAsn: 1.311 ± 0.046	2.839SerPro: 2.839 ± 0.074	1.124SerGln: 1.124 ± 0.042	3.286SerArg: 3.286 ± 0.076	3.062SerSer: 3.062 ± 0.078	2.828SerThr: 2.828 ± 0.077	4.028SerVal: 4.028 ± 0.086	0.69SerTrp: 0.69 ± 0.034	1.044SerTyr: 1.044 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	6.499ThrAla: 6.499 ± 0.101	0.534ThrCys: 0.534 ± 0.029	3.171ThrAsp: 3.171 ± 0.067	3.395ThrGlu: 3.395 ± 0.07	2.212ThrPhe: 2.212 ± 0.057	5.051ThrGly: 5.051 ± 0.097	1.119ThrHis: 1.119 ± 0.036	2.786ThrIle: 2.786 ± 0.067	2.169ThrLys: 2.169 ± 0.052	6.126ThrLeu: 6.126 ± 0.095	1.419ThrMet: 1.419 ± 0.042	1.457ThrAsn: 1.457 ± 0.05	3.728ThrPro: 3.728 ± 0.076	1.345ThrGln: 1.345 ± 0.039	3.074ThrArg: 3.074 ± 0.074	2.763ThrSer: 2.763 ± 0.07	3.226ThrThr: 3.226 ± 0.069	5.005ThrVal: 5.005 ± 0.116	0.613ThrTrp: 0.613 ± 0.03	1.236ThrTyr: 1.236 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	8.036ValAla: 8.036 ± 0.109	0.831ValCys: 0.831 ± 0.036	4.238ValAsp: 4.238 ± 0.078	5.301ValGlu: 5.301 ± 0.109	3.211ValPhe: 3.211 ± 0.087	5.774ValGly: 5.774 ± 0.096	1.235ValHis: 1.235 ± 0.036	3.677ValIle: 3.677 ± 0.087	3.474ValLys: 3.474 ± 0.082	8.12ValLeu: 8.12 ± 0.14	2.141ValMet: 2.141 ± 0.061	2.206ValAsn: 2.206 ± 0.056	4.015ValPro: 4.015 ± 0.07	1.723ValGln: 1.723 ± 0.047	6.056ValArg: 6.056 ± 0.109	4.342ValSer: 4.342 ± 0.088	5.015ValThr: 5.015 ± 0.096	6.502ValVal: 6.502 ± 0.118	0.996ValTrp: 0.996 ± 0.04	1.49ValTyr: 1.49 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.43TrpAla: 1.43 ± 0.048	0.211TrpCys: 0.211 ± 0.014	0.617TrpAsp: 0.617 ± 0.029	0.696TrpGlu: 0.696 ± 0.03	0.561TrpPhe: 0.561 ± 0.031	1.046TrpGly: 1.046 ± 0.044	0.255TrpHis: 0.255 ± 0.019	0.633TrpIle: 0.633 ± 0.033	0.612TrpLys: 0.612 ± 0.035	1.408TrpLeu: 1.408 ± 0.053	0.43TrpMet: 0.43 ± 0.022	0.423TrpAsn: 0.423 ± 0.021	0.524TrpPro: 0.524 ± 0.027	0.368TrpGln: 0.368 ± 0.024	1.157TrpArg: 1.157 ± 0.043	0.799TrpSer: 0.799 ± 0.04	0.877TrpThr: 0.877 ± 0.034	1.057TrpVal: 1.057 ± 0.049	0.218TrpTrp: 0.218 ± 0.022	0.275TrpTyr: 0.275 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.621TyrAla: 2.621 ± 0.068	0.271TyrCys: 0.271 ± 0.019	1.372TyrAsp: 1.372 ± 0.051	1.272TyrGlu: 1.272 ± 0.039	0.885TyrPhe: 0.885 ± 0.035	2.114TyrGly: 2.114 ± 0.062	0.368TyrHis: 0.368 ± 0.022	0.692TyrIle: 0.692 ± 0.032	0.652TyrLys: 0.652 ± 0.03	1.97TyrLeu: 1.97 ± 0.049	0.437TyrMet: 0.437 ± 0.026	0.577TyrAsn: 0.577 ± 0.028	0.925TyrPro: 0.925 ± 0.038	0.599TyrGln: 0.599 ± 0.031	1.5TyrArg: 1.5 ± 0.055	0.924TyrSer: 0.924 ± 0.045	1.017TyrThr: 1.017 ± 0.045	1.828TyrVal: 1.828 ± 0.052	0.328TyrTrp: 0.328 ± 0.019	0.517TyrTyr: 0.517 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2483 proteins (698141 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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