Amino acid dipepetide frequency for Nephila clavipes virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.165AlaAla: 4.165 ± 0.348
2.314AlaCys: 2.314 ± 0.06
3.702AlaAsp: 3.702 ± 0.057
2.776AlaGlu: 2.776 ± 0.991
3.702AlaPhe: 3.702 ± 0.702
5.553AlaGly: 5.553 ± 1.223
2.314AlaHis: 2.314 ± 0.06
6.016AlaIle: 6.016 ± 0.756
2.776AlaLys: 2.776 ± 1.286
7.404AlaLeu: 7.404 ± 0.646
2.314AlaMet: 2.314 ± 0.06
5.09AlaAsn: 5.09 ± 2.104
1.388AlaPro: 1.388 ± 0.643
1.388AlaGln: 1.388 ± 0.643
3.239AlaArg: 3.239 ± 0.994
4.627AlaSer: 4.627 ± 0.878
5.553AlaThr: 5.553 ± 2.741
3.702AlaVal: 3.702 ± 0.815
0.925AlaTrp: 0.925 ± 0.176
4.627AlaTyr: 4.627 ± 0.64
0.0AlaXaa: 0.0 ± 0.0
Cys
0.925CysAla: 0.925 ± 0.934
0.0CysCys: 0.0 ± 0.0
1.388CysAsp: 1.388 ± 0.116
0.925CysGlu: 0.925 ± 0.583
0.0CysPhe: 0.0 ± 0.0
0.463CysGly: 0.463 ± 0.292
0.0CysHis: 0.0 ± 0.0
1.851CysIle: 1.851 ± 1.11
0.463CysLys: 0.463 ± 0.292
0.925CysLeu: 0.925 ± 0.176
0.0CysMet: 0.0 ± 0.0
0.463CysAsn: 0.463 ± 0.292
0.463CysPro: 0.463 ± 0.467
0.463CysGln: 0.463 ± 0.292
0.0CysArg: 0.0 ± 0.0
0.463CysSer: 0.463 ± 0.292
0.925CysThr: 0.925 ± 0.934
1.388CysVal: 1.388 ± 0.643
0.463CysTrp: 0.463 ± 0.467
0.463CysTyr: 0.463 ± 0.292
0.0CysXaa: 0.0 ± 0.0
Asp
4.627AspAla: 4.627 ± 1.399
0.463AspCys: 0.463 ± 0.467
5.553AspAsp: 5.553 ± 1.223
1.388AspGlu: 1.388 ± 0.116
1.851AspPhe: 1.851 ± 1.166
2.314AspGly: 2.314 ± 0.699
1.388AspHis: 1.388 ± 0.875
5.553AspIle: 5.553 ± 1.053
4.165AspLys: 4.165 ± 0.411
4.627AspLeu: 4.627 ± 0.64
1.388AspMet: 1.388 ± 0.116
2.314AspAsn: 2.314 ± 1.577
2.776AspPro: 2.776 ± 0.991
2.776AspGln: 2.776 ± 0.991
1.388AspArg: 1.388 ± 0.643
6.016AspSer: 6.016 ± 1.521
2.776AspThr: 2.776 ± 0.232
4.165AspVal: 4.165 ± 0.411
0.925AspTrp: 0.925 ± 0.176
4.627AspTyr: 4.627 ± 0.878
0.0AspXaa: 0.0 ± 0.0
Glu
2.314GluAla: 2.314 ± 0.06
1.388GluCys: 1.388 ± 0.116
2.314GluAsp: 2.314 ± 1.577
2.776GluGlu: 2.776 ± 0.991
1.851GluPhe: 1.851 ± 1.166
1.388GluGly: 1.388 ± 0.116
0.463GluHis: 0.463 ± 0.292
2.776GluIle: 2.776 ± 0.991
3.239GluLys: 3.239 ± 1.283
3.702GluLeu: 3.702 ± 0.057
2.776GluMet: 2.776 ± 1.619
1.388GluAsn: 1.388 ± 0.116
0.463GluPro: 0.463 ± 0.467
1.388GluGln: 1.388 ± 0.875
5.09GluArg: 5.09 ± 0.173
5.09GluSer: 5.09 ± 0.586
4.165GluThr: 4.165 ± 1.107
2.776GluVal: 2.776 ± 1.286
1.388GluTrp: 1.388 ± 0.116
2.314GluTyr: 2.314 ± 0.699
0.0GluXaa: 0.0 ± 0.0
Phe
5.553PheAla: 5.553 ± 3.33
1.388PheCys: 1.388 ± 0.116
3.702PheAsp: 3.702 ± 0.057
1.851PheGlu: 1.851 ± 1.166
1.851PhePhe: 1.851 ± 0.351
3.702PheGly: 3.702 ± 1.574
1.851PheHis: 1.851 ± 0.408
2.776PheIle: 2.776 ± 0.991
3.239PheLys: 3.239 ± 0.524
5.09PheLeu: 5.09 ± 1.69
2.314PheMet: 2.314 ± 0.699
2.776PheAsn: 2.776 ± 0.527
1.851PhePro: 1.851 ± 0.408
0.925PheGln: 0.925 ± 0.176
1.851PheArg: 1.851 ± 1.166
4.165PheSer: 4.165 ± 1.169
1.388PheThr: 1.388 ± 0.643
1.851PheVal: 1.851 ± 0.351
0.0PheTrp: 0.0 ± 0.0
2.776PheTyr: 2.776 ± 0.991
0.0PheXaa: 0.0 ± 0.0
Gly
4.627GlyAla: 4.627 ± 0.878
0.925GlyCys: 0.925 ± 0.583
2.314GlyAsp: 2.314 ± 0.06
2.776GlyGlu: 2.776 ± 1.286
3.239GlyPhe: 3.239 ± 0.524
1.388GlyGly: 1.388 ± 0.643
0.463GlyHis: 0.463 ± 0.467
5.09GlyIle: 5.09 ± 1.345
3.239GlyLys: 3.239 ± 0.524
2.776GlyLeu: 2.776 ± 0.232
1.851GlyMet: 1.851 ± 0.408
1.388GlyAsn: 1.388 ± 0.875
0.463GlyPro: 0.463 ± 0.292
1.388GlyGln: 1.388 ± 0.116
2.776GlyArg: 2.776 ± 0.527
2.314GlySer: 2.314 ± 0.818
3.239GlyThr: 3.239 ± 2.041
3.239GlyVal: 3.239 ± 0.994
0.463GlyTrp: 0.463 ± 0.292
2.314GlyTyr: 2.314 ± 0.06
0.0GlyXaa: 0.0 ± 0.0
His
2.314HisAla: 2.314 ± 0.818
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.388HisGlu: 1.388 ± 0.875
0.925HisPhe: 0.925 ± 0.583
1.388HisGly: 1.388 ± 0.116
0.463HisHis: 0.463 ± 0.292
1.851HisIle: 1.851 ± 1.166
1.388HisLys: 1.388 ± 0.643
0.925HisLeu: 0.925 ± 0.176
0.925HisMet: 0.925 ± 0.934
0.463HisAsn: 0.463 ± 0.292
1.388HisPro: 1.388 ± 0.116
0.463HisGln: 0.463 ± 0.292
1.388HisArg: 1.388 ± 0.643
3.702HisSer: 3.702 ± 0.057
2.314HisThr: 2.314 ± 0.818
0.925HisVal: 0.925 ± 0.176
0.0HisTrp: 0.0 ± 0.0
0.463HisTyr: 0.463 ± 0.292
0.0HisXaa: 0.0 ± 0.0
Ile
5.09IleAla: 5.09 ± 0.586
0.925IleCys: 0.925 ± 0.934
5.09IleAsp: 5.09 ± 0.173
4.165IleGlu: 4.165 ± 0.348
5.09IlePhe: 5.09 ± 0.173
3.702IleGly: 3.702 ± 0.057
1.388IleHis: 1.388 ± 0.643
6.478IleIle: 6.478 ± 1.229
3.702IleLys: 3.702 ± 0.815
6.016IleLeu: 6.016 ± 0.756
1.851IleMet: 1.851 ± 0.351
2.314IleAsn: 2.314 ± 0.06
3.239IlePro: 3.239 ± 0.994
3.239IleGln: 3.239 ± 0.524
6.016IleArg: 6.016 ± 1.515
8.329IleSer: 8.329 ± 3.098
8.329IleThr: 8.329 ± 0.821
5.09IleVal: 5.09 ± 2.104
0.463IleTrp: 0.463 ± 0.467
1.851IleTyr: 1.851 ± 0.351
0.0IleXaa: 0.0 ± 0.0
Lys
3.239LysAla: 3.239 ± 0.235
0.0LysCys: 0.0 ± 0.0
4.627LysAsp: 4.627 ± 0.878
4.165LysGlu: 4.165 ± 0.348
3.239LysPhe: 3.239 ± 1.753
0.0LysGly: 0.0 ± 0.0
1.388LysHis: 1.388 ± 0.116
6.941LysIle: 6.941 ± 0.58
3.702LysLys: 3.702 ± 1.574
5.09LysLeu: 5.09 ± 0.586
1.388LysMet: 1.388 ± 0.116
2.314LysAsn: 2.314 ± 0.699
1.851LysPro: 1.851 ± 1.11
0.463LysGln: 0.463 ± 0.292
2.776LysArg: 2.776 ± 0.232
3.239LysSer: 3.239 ± 1.283
2.776LysThr: 2.776 ± 0.991
3.702LysVal: 3.702 ± 1.574
1.388LysTrp: 1.388 ± 0.116
1.851LysTyr: 1.851 ± 1.166
0.0LysXaa: 0.0 ± 0.0
Leu
6.016LeuAla: 6.016 ± 0.762
0.925LeuCys: 0.925 ± 0.176
3.239LeuAsp: 3.239 ± 2.041
4.627LeuGlu: 4.627 ± 0.64
3.702LeuPhe: 3.702 ± 0.815
4.627LeuGly: 4.627 ± 1.637
1.388LeuHis: 1.388 ± 0.643
6.016LeuIle: 6.016 ± 1.521
4.165LeuLys: 4.165 ± 0.411
10.18LeuLeu: 10.18 ± 0.345
1.851LeuMet: 1.851 ± 0.408
5.553LeuAsn: 5.553 ± 1.812
3.239LeuPro: 3.239 ± 2.512
2.314LeuGln: 2.314 ± 0.699
7.404LeuArg: 7.404 ± 1.631
6.478LeuSer: 6.478 ± 1.229
6.478LeuThr: 6.478 ± 0.289
5.09LeuVal: 5.09 ± 0.931
1.851LeuTrp: 1.851 ± 0.351
4.165LeuTyr: 4.165 ± 0.411
0.0LeuXaa: 0.0 ± 0.0
Met
3.239MetAla: 3.239 ± 0.524
0.463MetCys: 0.463 ± 0.292
1.388MetAsp: 1.388 ± 0.643
1.851MetGlu: 1.851 ± 0.408
0.925MetPhe: 0.925 ± 0.176
0.925MetGly: 0.925 ± 0.176
1.388MetHis: 1.388 ± 0.116
1.388MetIle: 1.388 ± 0.643
0.463MetLys: 0.463 ± 0.292
1.851MetLeu: 1.851 ± 1.166
0.463MetMet: 0.463 ± 0.467
0.925MetAsn: 0.925 ± 0.176
2.776MetPro: 2.776 ± 0.232
1.388MetGln: 1.388 ± 0.643
1.851MetArg: 1.851 ± 1.166
3.239MetSer: 3.239 ± 0.524
0.0MetThr: 0.0 ± 0.0
1.388MetVal: 1.388 ± 0.116
0.463MetTrp: 0.463 ± 0.467
0.925MetTyr: 0.925 ± 0.176
0.0MetXaa: 0.0 ± 0.0
Asn
5.553AsnAla: 5.553 ± 1.053
0.0AsnCys: 0.0 ± 0.0
3.702AsnAsp: 3.702 ± 1.461
2.314AsnGlu: 2.314 ± 0.818
2.776AsnPhe: 2.776 ± 0.527
0.463AsnGly: 0.463 ± 0.292
0.925AsnHis: 0.925 ± 0.583
5.09AsnIle: 5.09 ± 0.931
2.776AsnLys: 2.776 ± 0.991
4.627AsnLeu: 4.627 ± 0.878
0.925AsnMet: 0.925 ± 0.176
2.776AsnAsn: 2.776 ± 0.991
2.314AsnPro: 2.314 ± 0.699
1.388AsnGln: 1.388 ± 0.643
2.314AsnArg: 2.314 ± 0.699
2.314AsnSer: 2.314 ± 0.818
1.851AsnThr: 1.851 ± 0.351
4.627AsnVal: 4.627 ± 0.119
0.0AsnTrp: 0.0 ± 0.0
2.314AsnTyr: 2.314 ± 0.818
0.0AsnXaa: 0.0 ± 0.0
Pro
3.702ProAla: 3.702 ± 0.815
0.0ProCys: 0.0 ± 0.0
3.239ProAsp: 3.239 ± 1.753
3.239ProGlu: 3.239 ± 1.283
1.851ProPhe: 1.851 ± 1.869
1.851ProGly: 1.851 ± 1.869
1.851ProHis: 1.851 ± 1.166
1.388ProIle: 1.388 ± 0.116
1.851ProLys: 1.851 ± 1.166
3.702ProLeu: 3.702 ± 1.461
0.463ProMet: 0.463 ± 0.467
2.314ProAsn: 2.314 ± 0.699
1.851ProPro: 1.851 ± 1.11
0.463ProGln: 0.463 ± 0.292
1.851ProArg: 1.851 ± 0.351
2.776ProSer: 2.776 ± 0.527
0.925ProThr: 0.925 ± 0.583
2.776ProVal: 2.776 ± 0.232
0.925ProTrp: 0.925 ± 0.934
1.388ProTyr: 1.388 ± 0.875
0.0ProXaa: 0.0 ± 0.0
Gln
2.776GlnAla: 2.776 ± 0.991
0.463GlnCys: 0.463 ± 0.467
0.925GlnAsp: 0.925 ± 0.176
1.388GlnGlu: 1.388 ± 0.116
0.463GlnPhe: 0.463 ± 0.292
2.776GlnGly: 2.776 ± 0.991
0.463GlnHis: 0.463 ± 0.292
1.851GlnIle: 1.851 ± 0.408
0.463GlnLys: 0.463 ± 0.292
3.702GlnLeu: 3.702 ± 0.702
0.0GlnMet: 0.0 ± 0.0
2.314GlnAsn: 2.314 ± 0.06
0.925GlnPro: 0.925 ± 0.583
0.463GlnGln: 0.463 ± 0.292
2.776GlnArg: 2.776 ± 0.232
2.314GlnSer: 2.314 ± 0.699
0.925GlnThr: 0.925 ± 0.583
2.314GlnVal: 2.314 ± 0.699
0.0GlnTrp: 0.0 ± 0.0
0.925GlnTyr: 0.925 ± 0.934
0.0GlnXaa: 0.0 ± 0.0
Arg
6.016ArgAla: 6.016 ± 0.003
0.463ArgCys: 0.463 ± 0.467
3.239ArgAsp: 3.239 ± 1.283
2.776ArgGlu: 2.776 ± 1.75
6.478ArgPhe: 6.478 ± 1.806
4.627ArgGly: 4.627 ± 0.878
0.463ArgHis: 0.463 ± 0.292
3.702ArgIle: 3.702 ± 0.057
5.09ArgLys: 5.09 ± 0.173
6.941ArgLeu: 6.941 ± 1.696
2.314ArgMet: 2.314 ± 0.699
3.702ArgAsn: 3.702 ± 0.815
1.388ArgPro: 1.388 ± 0.875
2.314ArgGln: 2.314 ± 0.06
3.239ArgArg: 3.239 ± 1.283
1.851ArgSer: 1.851 ± 1.869
0.925ArgThr: 0.925 ± 0.176
0.925ArgVal: 0.925 ± 0.176
0.463ArgTrp: 0.463 ± 0.292
3.239ArgTyr: 3.239 ± 0.524
0.0ArgXaa: 0.0 ± 0.0
Ser
3.702SerAla: 3.702 ± 2.333
0.463SerCys: 0.463 ± 0.467
3.239SerAsp: 3.239 ± 0.524
2.314SerGlu: 2.314 ± 0.699
3.702SerPhe: 3.702 ± 1.574
4.165SerGly: 4.165 ± 2.687
2.314SerHis: 2.314 ± 0.818
7.404SerIle: 7.404 ± 4.44
3.702SerLys: 3.702 ± 1.461
6.478SerLeu: 6.478 ± 1.229
1.388SerMet: 1.388 ± 0.193
3.239SerAsn: 3.239 ± 0.994
4.165SerPro: 4.165 ± 1.169
2.314SerGln: 2.314 ± 0.699
4.627SerArg: 4.627 ± 0.119
6.941SerSer: 6.941 ± 0.179
6.941SerThr: 6.941 ± 0.937
6.016SerVal: 6.016 ± 1.515
1.851SerTrp: 1.851 ± 0.408
2.776SerTyr: 2.776 ± 1.286
0.0SerXaa: 0.0 ± 0.0
Thr
2.776ThrAla: 2.776 ± 0.991
0.925ThrCys: 0.925 ± 0.934
4.627ThrAsp: 4.627 ± 0.64
3.239ThrGlu: 3.239 ± 0.524
2.314ThrPhe: 2.314 ± 0.699
2.776ThrGly: 2.776 ± 1.75
0.463ThrHis: 0.463 ± 0.292
5.09ThrIle: 5.09 ± 0.931
5.09ThrLys: 5.09 ± 0.931
6.941ThrLeu: 6.941 ± 0.179
1.388ThrMet: 1.388 ± 0.643
3.239ThrAsn: 3.239 ± 0.524
0.925ThrPro: 0.925 ± 0.583
2.776ThrGln: 2.776 ± 0.232
1.851ThrArg: 1.851 ± 0.408
4.165ThrSer: 4.165 ± 1.107
2.776ThrThr: 2.776 ± 0.991
3.239ThrVal: 3.239 ± 0.235
0.925ThrTrp: 0.925 ± 0.934
2.776ThrTyr: 2.776 ± 0.232
0.0ThrXaa: 0.0 ± 0.0
Val
4.627ValAla: 4.627 ± 0.64
0.925ValCys: 0.925 ± 0.583
4.627ValAsp: 4.627 ± 1.399
2.314ValGlu: 2.314 ± 0.818
3.239ValPhe: 3.239 ± 0.994
3.239ValGly: 3.239 ± 0.994
1.388ValHis: 1.388 ± 0.643
6.016ValIle: 6.016 ± 3.038
1.851ValLys: 1.851 ± 0.408
3.702ValLeu: 3.702 ± 0.057
1.851ValMet: 1.851 ± 0.408
4.165ValAsn: 4.165 ± 0.411
3.239ValPro: 3.239 ± 0.235
1.388ValGln: 1.388 ± 0.875
5.09ValArg: 5.09 ± 0.931
4.627ValSer: 4.627 ± 0.64
1.851ValThr: 1.851 ± 1.166
3.702ValVal: 3.702 ± 0.702
0.463ValTrp: 0.463 ± 0.467
3.702ValTyr: 3.702 ± 0.057
0.0ValXaa: 0.0 ± 0.0
Trp
0.925TrpAla: 0.925 ± 0.583
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.463TrpGlu: 0.463 ± 0.467
0.925TrpPhe: 0.925 ± 0.176
0.925TrpGly: 0.925 ± 0.583
0.925TrpHis: 0.925 ± 0.934
0.463TrpIle: 0.463 ± 0.467
1.388TrpLys: 1.388 ± 0.116
0.925TrpLeu: 0.925 ± 0.176
0.0TrpMet: 0.0 ± 0.0
1.388TrpAsn: 1.388 ± 0.116
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.851TrpArg: 1.851 ± 0.351
1.388TrpSer: 1.388 ± 1.402
0.925TrpThr: 0.925 ± 0.583
1.388TrpVal: 1.388 ± 1.402
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.388TyrAla: 1.388 ± 0.643
0.0TyrCys: 0.0 ± 0.0
4.165TyrAsp: 4.165 ± 0.348
2.314TyrGlu: 2.314 ± 1.577
2.776TyrPhe: 2.776 ± 0.991
0.0TyrGly: 0.0 ± 0.0
1.388TyrHis: 1.388 ± 0.643
4.627TyrIle: 4.627 ± 0.64
1.388TyrLys: 1.388 ± 0.643
3.702TyrLeu: 3.702 ± 0.702
1.388TyrMet: 1.388 ± 0.116
0.925TyrAsn: 0.925 ± 0.176
3.702TyrPro: 3.702 ± 0.815
0.925TyrGln: 0.925 ± 0.176
2.776TyrArg: 2.776 ± 1.286
4.165TyrSer: 4.165 ± 1.107
3.239TyrThr: 3.239 ± 1.283
3.702TyrVal: 3.702 ± 1.574
0.925TyrTrp: 0.925 ± 0.176
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2162 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski