Amino acid dipepetide frequency for Oryza barthii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.351AlaAla: 13.351 ± 0.068	1.552AlaCys: 1.552 ± 0.012	4.151AlaAsp: 4.151 ± 0.02	4.772AlaGlu: 4.772 ± 0.021	2.911AlaPhe: 2.911 ± 0.016	6.397AlaGly: 6.397 ± 0.032	1.692AlaHis: 1.692 ± 0.011	3.761AlaIle: 3.761 ± 0.019	3.698AlaLys: 3.698 ± 0.017	7.624AlaLeu: 7.624 ± 0.029	2.338AlaMet: 2.338 ± 0.013	2.61AlaAsn: 2.61 ± 0.016	4.395AlaPro: 4.395 ± 0.024	2.372AlaGln: 2.372 ± 0.014	5.194AlaArg: 5.194 ± 0.021	7.19AlaSer: 7.19 ± 0.026	4.754AlaThr: 4.754 ± 0.019	6.583AlaVal: 6.583 ± 0.027	0.997AlaTrp: 0.997 ± 0.008	1.891AlaTyr: 1.891 ± 0.012	0.01AlaXaa: 0.01 ± 0.001
Cys	1.327CysAla: 1.327 ± 0.01	0.626CysCys: 0.626 ± 0.007	0.929CysAsp: 0.929 ± 0.009	0.833CysGlu: 0.833 ± 0.008	0.836CysPhe: 0.836 ± 0.008	1.526CysGly: 1.526 ± 0.013	0.541CysHis: 0.541 ± 0.006	0.963CysIle: 0.963 ± 0.008	0.971CysLys: 0.971 ± 0.01	1.876CysLeu: 1.876 ± 0.012	0.47CysMet: 0.47 ± 0.006	0.767CysAsn: 0.767 ± 0.009	1.021CysPro: 1.021 ± 0.01	0.595CysGln: 0.595 ± 0.007	1.328CysArg: 1.328 ± 0.01	1.945CysSer: 1.945 ± 0.014	0.967CysThr: 0.967 ± 0.009	1.156CysVal: 1.156 ± 0.009	0.273CysTrp: 0.273 ± 0.004	0.538CysTyr: 0.538 ± 0.006	0.002CysXaa: 0.002 ± 0.0
Asp	4.602AspAla: 4.602 ± 0.02	0.949AspCys: 0.949 ± 0.009	4.396AspAsp: 4.396 ± 0.028	3.961AspGlu: 3.961 ± 0.023	1.996AspPhe: 1.996 ± 0.013	4.749AspGly: 4.749 ± 0.018	1.295AspHis: 1.295 ± 0.01	2.796AspIle: 2.796 ± 0.017	2.466AspLys: 2.466 ± 0.015	4.91AspLeu: 4.91 ± 0.02	1.454AspMet: 1.454 ± 0.01	1.895AspAsn: 1.895 ± 0.012	2.61AspPro: 2.61 ± 0.014	1.616AspGln: 1.616 ± 0.012	2.667AspArg: 2.667 ± 0.016	3.712AspSer: 3.712 ± 0.02	2.238AspThr: 2.238 ± 0.013	3.812AspVal: 3.812 ± 0.017	0.69AspTrp: 0.69 ± 0.007	1.4AspTyr: 1.4 ± 0.01	0.004AspXaa: 0.004 ± 0.001
Glu	5.267GluAla: 5.267 ± 0.02	0.883GluCys: 0.883 ± 0.009	3.68GluAsp: 3.68 ± 0.021	5.846GluGlu: 5.846 ± 0.032	2.028GluPhe: 2.028 ± 0.012	3.711GluGly: 3.711 ± 0.016	1.408GluHis: 1.408 ± 0.011	3.062GluIle: 3.062 ± 0.018	3.739GluLys: 3.739 ± 0.02	5.975GluLeu: 5.975 ± 0.03	1.733GluMet: 1.733 ± 0.012	2.303GluAsn: 2.303 ± 0.017	2.219GluPro: 2.219 ± 0.014	2.209GluGln: 2.209 ± 0.014	3.589GluArg: 3.589 ± 0.017	3.768GluSer: 3.768 ± 0.018	2.588GluThr: 2.588 ± 0.016	4.056GluVal: 4.056 ± 0.018	0.765GluTrp: 0.765 ± 0.008	1.512GluTyr: 1.512 ± 0.01	0.005GluXaa: 0.005 ± 0.001
Phe	2.756PheAla: 2.756 ± 0.014	0.792PheCys: 0.792 ± 0.008	2.12PheAsp: 2.12 ± 0.013	1.836PheGlu: 1.836 ± 0.011	1.696PhePhe: 1.696 ± 0.014	2.872PheGly: 2.872 ± 0.019	1.007PheHis: 1.007 ± 0.009	1.679PheIle: 1.679 ± 0.011	1.502PheLys: 1.502 ± 0.011	3.879PheLeu: 3.879 ± 0.017	0.893PheMet: 0.893 ± 0.008	1.326PheAsn: 1.326 ± 0.011	1.873PhePro: 1.873 ± 0.013	1.273PheGln: 1.273 ± 0.009	2.004PheArg: 2.004 ± 0.013	3.341PheSer: 3.341 ± 0.018	1.781PheThr: 1.781 ± 0.012	2.624PheVal: 2.624 ± 0.013	0.508PheTrp: 0.508 ± 0.006	1.063PheTyr: 1.063 ± 0.008	0.003PheXaa: 0.003 ± 0.0
Gly	5.818GlyAla: 5.818 ± 0.03	1.521GlyCys: 1.521 ± 0.013	4.22GlyAsp: 4.22 ± 0.017	4.204GlyGlu: 4.204 ± 0.018	2.826GlyPhe: 2.826 ± 0.015	8.504GlyGly: 8.504 ± 0.052	1.778GlyHis: 1.778 ± 0.013	3.235GlyIle: 3.235 ± 0.016	3.601GlyLys: 3.601 ± 0.019	5.845GlyLeu: 5.845 ± 0.023	1.704GlyMet: 1.704 ± 0.012	2.823GlyAsn: 2.823 ± 0.016	2.6GlyPro: 2.6 ± 0.015	2.167GlyGln: 2.167 ± 0.013	4.765GlyArg: 4.765 ± 0.023	6.056GlySer: 6.056 ± 0.022	3.375GlyThr: 3.375 ± 0.018	4.737GlyVal: 4.737 ± 0.021	1.022GlyTrp: 1.022 ± 0.008	2.061GlyTyr: 2.061 ± 0.014	0.007GlyXaa: 0.007 ± 0.001
His	1.882HisAla: 1.882 ± 0.012	0.565HisCys: 0.565 ± 0.007	1.295HisAsp: 1.295 ± 0.009	1.251HisGlu: 1.251 ± 0.009	0.925HisPhe: 0.925 ± 0.008	2.165HisGly: 2.165 ± 0.013	1.106HisHis: 1.106 ± 0.012	1.12HisIle: 1.12 ± 0.01	1.009HisLys: 1.009 ± 0.009	2.661HisLeu: 2.661 ± 0.017	0.576HisMet: 0.576 ± 0.006	0.847HisAsn: 0.847 ± 0.009	1.521HisPro: 1.521 ± 0.012	0.97HisGln: 0.97 ± 0.009	1.765HisArg: 1.765 ± 0.012	1.737HisSer: 1.737 ± 0.012	0.996HisThr: 0.996 ± 0.008	1.64HisVal: 1.64 ± 0.011	0.299HisTrp: 0.299 ± 0.004	0.663HisTyr: 0.663 ± 0.007	0.003HisXaa: 0.003 ± 0.0
Ile	3.633IleAla: 3.633 ± 0.016	1.03IleCys: 1.03 ± 0.008	2.605IleAsp: 2.605 ± 0.015	2.562IleGlu: 2.562 ± 0.016	1.798IlePhe: 1.798 ± 0.013	3.164IleGly: 3.164 ± 0.017	1.18IleHis: 1.18 ± 0.009	2.351IleIle: 2.351 ± 0.016	2.315IleLys: 2.315 ± 0.014	4.497IleLeu: 4.497 ± 0.021	1.031IleMet: 1.031 ± 0.008	1.758IleAsn: 1.758 ± 0.012	2.595IlePro: 2.595 ± 0.017	1.617IleGln: 1.617 ± 0.011	2.455IleArg: 2.455 ± 0.014	4.103IleSer: 4.103 ± 0.019	2.393IleThr: 2.393 ± 0.013	3.138IleVal: 3.138 ± 0.019	0.626IleTrp: 0.626 ± 0.007	1.297IleTyr: 1.297 ± 0.009	0.004IleXaa: 0.004 ± 0.001
Lys	3.747LysAla: 3.747 ± 0.017	0.843LysCys: 0.843 ± 0.008	2.706LysAsp: 2.706 ± 0.016	3.679LysGlu: 3.679 ± 0.021	1.643LysPhe: 1.643 ± 0.012	3.044LysGly: 3.044 ± 0.017	1.175LysHis: 1.175 ± 0.011	2.636LysIle: 2.636 ± 0.015	3.596LysLys: 3.596 ± 0.025	5.039LysLeu: 5.039 ± 0.023	1.283LysMet: 1.283 ± 0.009	2.044LysAsn: 2.044 ± 0.014	2.268LysPro: 2.268 ± 0.017	1.883LysGln: 1.883 ± 0.013	3.114LysArg: 3.114 ± 0.016	3.448LysSer: 3.448 ± 0.021	2.25LysThr: 2.25 ± 0.012	3.218LysVal: 3.218 ± 0.016	0.6LysTrp: 0.6 ± 0.007	1.342LysTyr: 1.342 ± 0.01	0.004LysXaa: 0.004 ± 0.001
Leu	7.989LeuAla: 7.989 ± 0.029	1.867LeuCys: 1.867 ± 0.014	5.16LeuAsp: 5.16 ± 0.021	5.785LeuGlu: 5.785 ± 0.03	3.42LeuPhe: 3.42 ± 0.017	5.907LeuGly: 5.907 ± 0.023	2.828LeuHis: 2.828 ± 0.017	3.844LeuIle: 3.844 ± 0.02	4.848LeuLys: 4.848 ± 0.025	10.688LeuLeu: 10.688 ± 0.039	2.057LeuMet: 2.057 ± 0.011	3.155LeuAsn: 3.155 ± 0.016	5.878LeuPro: 5.878 ± 0.024	4.132LeuGln: 4.132 ± 0.02	6.332LeuArg: 6.332 ± 0.026	7.981LeuSer: 7.981 ± 0.031	4.389LeuThr: 4.389 ± 0.021	6.564LeuVal: 6.564 ± 0.022	1.167LeuTrp: 1.167 ± 0.01	2.338LeuTyr: 2.338 ± 0.012	0.009LeuXaa: 0.009 ± 0.001
Met	2.82MetAla: 2.82 ± 0.015	0.358MetCys: 0.358 ± 0.004	1.492MetAsp: 1.492 ± 0.01	1.925MetGlu: 1.925 ± 0.013	0.788MetPhe: 0.788 ± 0.008	1.548MetGly: 1.548 ± 0.01	0.597MetHis: 0.597 ± 0.007	1.044MetIle: 1.044 ± 0.009	1.316MetLys: 1.316 ± 0.011	2.314MetLeu: 2.314 ± 0.013	0.694MetMet: 0.694 ± 0.007	0.883MetAsn: 0.883 ± 0.009	1.301MetPro: 1.301 ± 0.01	0.916MetGln: 0.916 ± 0.008	1.389MetArg: 1.389 ± 0.01	1.791MetSer: 1.791 ± 0.01	1.083MetThr: 1.083 ± 0.008	1.749MetVal: 1.749 ± 0.011	0.298MetTrp: 0.298 ± 0.004	0.591MetTyr: 0.591 ± 0.007	0.002MetXaa: 0.002 ± 0.0
Asn	2.629AsnAla: 2.629 ± 0.015	0.76AsnCys: 0.76 ± 0.008	1.76AsnAsp: 1.76 ± 0.013	1.887AsnGlu: 1.887 ± 0.014	1.465AsnPhe: 1.465 ± 0.011	2.891AsnGly: 2.891 ± 0.017	0.917AsnHis: 0.917 ± 0.007	2.102AsnIle: 2.102 ± 0.015	1.872AsnLys: 1.872 ± 0.013	4.0AsnLeu: 4.0 ± 0.028	1.028AsnMet: 1.028 ± 0.008	1.831AsnAsn: 1.831 ± 0.015	1.878AsnPro: 1.878 ± 0.013	1.31AsnGln: 1.31 ± 0.01	1.777AsnArg: 1.777 ± 0.011	2.946AsnSer: 2.946 ± 0.016	1.751AsnThr: 1.751 ± 0.013	2.306AsnVal: 2.306 ± 0.014	0.447AsnTrp: 0.447 ± 0.006	1.034AsnTyr: 1.034 ± 0.008	0.003AsnXaa: 0.003 ± 0.0
Pro	4.897ProAla: 4.897 ± 0.026	0.952ProCys: 0.952 ± 0.009	2.688ProAsp: 2.688 ± 0.015	3.182ProGlu: 3.182 ± 0.018	1.856ProPhe: 1.856 ± 0.011	3.124ProGly: 3.124 ± 0.015	1.251ProHis: 1.251 ± 0.01	1.976ProIle: 1.976 ± 0.013	2.265ProLys: 2.265 ± 0.017	4.559ProLeu: 4.559 ± 0.022	1.09ProMet: 1.09 ± 0.01	1.905ProAsn: 1.905 ± 0.013	5.452ProPro: 5.452 ± 0.045	1.729ProGln: 1.729 ± 0.013	3.321ProArg: 3.321 ± 0.017	5.332ProSer: 5.332 ± 0.025	2.779ProThr: 2.779 ± 0.016	3.356ProVal: 3.356 ± 0.017	0.695ProTrp: 0.695 ± 0.007	1.264ProTyr: 1.264 ± 0.011	0.006ProXaa: 0.006 ± 0.001
Gln	2.562GlnAla: 2.562 ± 0.016	0.607GlnCys: 0.607 ± 0.006	1.616GlnAsp: 1.616 ± 0.012	2.283GlnGlu: 2.283 ± 0.015	1.167GlnPhe: 1.167 ± 0.01	2.156GlnGly: 2.156 ± 0.014	0.996GlnHis: 0.996 ± 0.008	1.665GlnIle: 1.665 ± 0.01	1.85GlnLys: 1.85 ± 0.011	3.584GlnLeu: 3.584 ± 0.017	0.935GlnMet: 0.935 ± 0.009	1.376GlnAsn: 1.376 ± 0.01	1.873GlnPro: 1.873 ± 0.015	2.196GlnGln: 2.196 ± 0.026	2.224GlnArg: 2.224 ± 0.014	2.431GlnSer: 2.431 ± 0.016	1.461GlnThr: 1.461 ± 0.01	2.16GlnVal: 2.16 ± 0.011	0.47GlnTrp: 0.47 ± 0.006	0.875GlnTyr: 0.875 ± 0.007	0.003GlnXaa: 0.003 ± 0.0
Arg	4.804ArgAla: 4.804 ± 0.022	1.363ArgCys: 1.363 ± 0.01	2.914ArgAsp: 2.914 ± 0.013	3.479ArgGlu: 3.479 ± 0.016	2.2ArgPhe: 2.2 ± 0.014	4.286ArgGly: 4.286 ± 0.018	1.705ArgHis: 1.705 ± 0.013	2.696ArgIle: 2.696 ± 0.014	3.31ArgLys: 3.31 ± 0.015	5.974ArgLeu: 5.974 ± 0.021	1.539ArgMet: 1.539 ± 0.011	2.159ArgAsn: 2.159 ± 0.014	3.159ArgPro: 3.159 ± 0.017	2.061ArgGln: 2.061 ± 0.011	6.827ArgArg: 6.827 ± 0.037	4.893ArgSer: 4.893 ± 0.023	2.637ArgThr: 2.637 ± 0.015	3.739ArgVal: 3.739 ± 0.016	1.09ArgTrp: 1.09 ± 0.009	1.611ArgTyr: 1.611 ± 0.012	0.007ArgXaa: 0.007 ± 0.001
Ser	6.311SerAla: 6.311 ± 0.023	1.795SerCys: 1.795 ± 0.013	4.07SerAsp: 4.07 ± 0.022	4.025SerGlu: 4.025 ± 0.02	3.321SerPhe: 3.321 ± 0.014	6.039SerGly: 6.039 ± 0.028	1.839SerHis: 1.839 ± 0.011	3.833SerIle: 3.833 ± 0.021	3.805SerLys: 3.805 ± 0.021	7.976SerLeu: 7.976 ± 0.031	2.07SerMet: 2.07 ± 0.011	3.229SerAsn: 3.229 ± 0.019	4.922SerPro: 4.922 ± 0.026	2.511SerGln: 2.511 ± 0.015	4.736SerArg: 4.736 ± 0.018	10.385SerSer: 10.385 ± 0.045	4.544SerThr: 4.544 ± 0.019	4.85SerVal: 4.85 ± 0.021	1.179SerTrp: 1.179 ± 0.01	2.153SerTyr: 2.153 ± 0.014	0.007SerXaa: 0.007 ± 0.001
Thr	4.385ThrAla: 4.385 ± 0.017	0.944ThrCys: 0.944 ± 0.008	2.318ThrAsp: 2.318 ± 0.013	2.592ThrGlu: 2.592 ± 0.015	1.789ThrPhe: 1.789 ± 0.013	3.513ThrGly: 3.513 ± 0.016	0.97ThrHis: 0.97 ± 0.007	2.427ThrIle: 2.427 ± 0.014	2.264ThrLys: 2.264 ± 0.012	4.286ThrLeu: 4.286 ± 0.02	1.305ThrMet: 1.305 ± 0.008	1.825ThrAsn: 1.825 ± 0.013	2.765ThrPro: 2.765 ± 0.016	1.342ThrGln: 1.342 ± 0.009	2.623ThrArg: 2.623 ± 0.013	4.395ThrSer: 4.395 ± 0.019	3.28ThrThr: 3.28 ± 0.017	3.529ThrVal: 3.529 ± 0.014	0.636ThrTrp: 0.636 ± 0.006	1.3ThrTyr: 1.3 ± 0.011	0.005ThrXaa: 0.005 ± 0.001
Val	6.622ValAla: 6.622 ± 0.024	1.18ValCys: 1.18 ± 0.009	3.931ValAsp: 3.931 ± 0.016	4.141ValGlu: 4.141 ± 0.019	2.54ValPhe: 2.54 ± 0.015	4.501ValGly: 4.501 ± 0.021	1.677ValHis: 1.677 ± 0.012	2.998ValIle: 2.998 ± 0.016	3.147ValLys: 3.147 ± 0.017	6.676ValLeu: 6.676 ± 0.023	1.588ValMet: 1.588 ± 0.01	2.123ValAsn: 2.123 ± 0.012	3.545ValPro: 3.545 ± 0.015	2.279ValGln: 2.279 ± 0.011	3.716ValArg: 3.716 ± 0.017	5.072ValSer: 5.072 ± 0.018	3.307ValThr: 3.307 ± 0.015	5.736ValVal: 5.736 ± 0.025	0.815ValTrp: 0.815 ± 0.008	1.803ValTyr: 1.803 ± 0.011	0.005ValXaa: 0.005 ± 0.001
Trp	0.946TrpAla: 0.946 ± 0.009	0.28TrpCys: 0.28 ± 0.005	0.669TrpAsp: 0.669 ± 0.007	0.749TrpGlu: 0.749 ± 0.007	0.492TrpPhe: 0.492 ± 0.008	0.774TrpGly: 0.774 ± 0.008	0.32TrpHis: 0.32 ± 0.005	0.643TrpIle: 0.643 ± 0.007	0.767TrpLys: 0.767 ± 0.007	1.284TrpLeu: 1.284 ± 0.009	0.382TrpMet: 0.382 ± 0.005	0.584TrpAsn: 0.584 ± 0.007	0.605TrpPro: 0.605 ± 0.007	0.464TrpGln: 0.464 ± 0.006	1.148TrpArg: 1.148 ± 0.011	1.046TrpSer: 1.046 ± 0.008	0.672TrpThr: 0.672 ± 0.006	0.797TrpVal: 0.797 ± 0.008	0.286TrpTrp: 0.286 ± 0.005	0.336TrpTyr: 0.336 ± 0.005	0.002TrpXaa: 0.002 ± 0.0
Tyr	1.886TyrAla: 1.886 ± 0.013	0.616TyrCys: 0.616 ± 0.007	1.495TyrAsp: 1.495 ± 0.011	1.346TyrGlu: 1.346 ± 0.01	1.129TyrPhe: 1.129 ± 0.01	1.991TyrGly: 1.991 ± 0.014	0.712TyrHis: 0.712 ± 0.006	1.316TyrIle: 1.316 ± 0.009	1.216TyrLys: 1.216 ± 0.01	2.681TyrLeu: 2.681 ± 0.015	0.726TyrMet: 0.726 ± 0.007	1.153TyrAsn: 1.153 ± 0.009	1.193TyrPro: 1.193 ± 0.01	0.846TyrGln: 0.846 ± 0.008	1.47TyrArg: 1.47 ± 0.009	2.018TyrSer: 2.018 ± 0.014	1.242TyrThr: 1.242 ± 0.01	1.647TyrVal: 1.647 ± 0.011	0.384TyrTrp: 0.384 ± 0.005	0.926TyrTyr: 0.926 ± 0.009	0.003TyrXaa: 0.003 ± 0.0
Xaa	0.009XaaAla: 0.009 ± 0.001	0.002XaaCys: 0.002 ± 0.0	0.006XaaAsp: 0.006 ± 0.001	0.007XaaGlu: 0.007 ± 0.001	0.003XaaPhe: 0.003 ± 0.0	0.006XaaGly: 0.006 ± 0.001	0.002XaaHis: 0.002 ± 0.0	0.004XaaIle: 0.004 ± 0.001	0.003XaaLys: 0.003 ± 0.0	0.008XaaLeu: 0.008 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.003XaaAsn: 0.003 ± 0.0	0.006XaaPro: 0.006 ± 0.001	0.003XaaGln: 0.003 ± 0.0	0.006XaaArg: 0.006 ± 0.001	0.008XaaSer: 0.008 ± 0.001	0.004XaaThr: 0.004 ± 0.001	0.007XaaVal: 0.007 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.013XaaXaa: 0.013 ± 0.003

Statistics based on 40214 proteins (16234674 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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