Acremonium chrysogenum (strain ATCC 11550 / CBS 779.69 / DSM 880 / JCM 23072 / IMI 49137)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; sordariomyceta; Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreales incertae sedis; Acremonium; Acremonium chrysogenum

Average proteome isoelectric point is 6.46

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8899 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A086T0U6|A0A086T0U6_ACRC1 F-box domain-containing protein OS=Acremonium chrysogenum (strain ATCC 11550 / CBS 779.69 / DSM 880 / JCM 23072 / IMI 49137) OX=857340 GN=ACRE_062610 PE=4 SV=1
MM1 pKa = 7.78LDD3 pKa = 3.64KK4 pKa = 11.05SFPLNALSLLLLGGQASATYY24 pKa = 9.59LYY26 pKa = 10.02VSSYY30 pKa = 11.08SGIITTLKK38 pKa = 10.74LNGSGSEE45 pKa = 4.13TTLEE49 pKa = 4.03AVSSNDD55 pKa = 2.97EE56 pKa = 4.4CGGSASWLTLDD67 pKa = 4.13PSNGVIYY74 pKa = 9.13CTDD77 pKa = 3.78EE78 pKa = 4.0AWAGPPGAITSFATHH93 pKa = 6.84EE94 pKa = 4.7DD95 pKa = 3.62GSLSVLDD102 pKa = 3.86TQEE105 pKa = 4.02TFVGGVSVVQYY116 pKa = 11.28GDD118 pKa = 3.45NNNGLGVAYY127 pKa = 10.42YY128 pKa = 10.28GGSAFTTWDD137 pKa = 3.27ATDD140 pKa = 3.84PAALDD145 pKa = 3.75LVDD148 pKa = 4.25EE149 pKa = 5.06FVFEE153 pKa = 4.72LEE155 pKa = 4.39EE156 pKa = 4.63PGANPDD162 pKa = 3.53RR163 pKa = 11.84QEE165 pKa = 4.26APHH168 pKa = 6.25PHH170 pKa = 5.73QAALDD175 pKa = 3.89PSGEE179 pKa = 4.26FILVPDD185 pKa = 4.75LGADD189 pKa = 3.89LVRR192 pKa = 11.84TYY194 pKa = 10.72RR195 pKa = 11.84VAEE198 pKa = 4.06GDD200 pKa = 3.82FAVTPSGDD208 pKa = 3.67LEE210 pKa = 4.4LPAGSGPRR218 pKa = 11.84HH219 pKa = 5.56LTFAVHH225 pKa = 7.23GDD227 pKa = 3.41TTYY230 pKa = 10.14MYY232 pKa = 11.14LVAEE236 pKa = 4.65LSNTIFGYY244 pKa = 7.68TVEE247 pKa = 4.39YY248 pKa = 9.87SSSGIDD254 pKa = 3.19FKK256 pKa = 11.19KK257 pKa = 9.8IYY259 pKa = 10.28EE260 pKa = 4.44SGTHH264 pKa = 6.01GEE266 pKa = 4.25GVEE269 pKa = 4.28VPEE272 pKa = 4.68GASAAEE278 pKa = 3.91IVVTSDD284 pKa = 2.71QKK286 pKa = 11.32YY287 pKa = 10.39LIVSSRR293 pKa = 11.84NEE295 pKa = 4.08NIFEE299 pKa = 4.33IPSFDD304 pKa = 3.96PDD306 pKa = 3.32SDD308 pKa = 3.67EE309 pKa = 4.94TIVSDD314 pKa = 3.43TLINFSIDD322 pKa = 3.35PATGALSQLQEE333 pKa = 4.22VPSGGRR339 pKa = 11.84VPRR342 pKa = 11.84HH343 pKa = 5.47FSLNADD349 pKa = 3.71EE350 pKa = 4.55TQVAVVQQSDD360 pKa = 3.53GRR362 pKa = 11.84VVLIEE367 pKa = 4.46RR368 pKa = 11.84DD369 pKa = 3.84PEE371 pKa = 4.71SGLLGDD377 pKa = 5.03FVAAADD383 pKa = 4.3VEE385 pKa = 4.79GQVNTVIFNEE395 pKa = 4.77LII397 pKa = 3.9

Molecular weight: 42.02 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A086SX64|A0A086SX64_ACRC1 Uncharacterized protein OS=Acremonium chrysogenum (strain ATCC 11550 / CBS 779.69 / DSM 880 / JCM 23072 / IMI 49137) OX=857340 GN=ACRE_075940 PE=4 SV=1
MM1 pKa = 7.26NALTRR6 pKa = 11.84SFTRR10 pKa = 11.84LAVRR14 pKa = 11.84PAGAATKK21 pKa = 10.25SSRR24 pKa = 11.84TFTTLSPHH32 pKa = 6.74RR33 pKa = 11.84PTVLPSAITTRR44 pKa = 11.84LPTSFTPSAGAGADD58 pKa = 3.88LVPTAAITRR67 pKa = 11.84HH68 pKa = 6.13PALQAIRR75 pKa = 11.84CGPRR79 pKa = 11.84NTMNGATRR87 pKa = 11.84MVQKK91 pKa = 10.21RR92 pKa = 11.84RR93 pKa = 11.84SGFLVRR99 pKa = 11.84KK100 pKa = 9.94RR101 pKa = 11.84SRR103 pKa = 11.84TGRR106 pKa = 11.84KK107 pKa = 8.1ILLRR111 pKa = 11.84RR112 pKa = 11.84RR113 pKa = 11.84MKK115 pKa = 10.2GRR117 pKa = 11.84RR118 pKa = 11.84EE119 pKa = 3.56IAQQ122 pKa = 3.29

Molecular weight: 13.39 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8899

0

8899

4365916

25

10359

490.6

54.11

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.127 ± 0.024

1.162 ± 0.01

6.094 ± 0.017

6.351 ± 0.026

3.459 ± 0.015

7.328 ± 0.026

2.426 ± 0.01

4.364 ± 0.017

4.62 ± 0.025

8.637 ± 0.029

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.23 ± 0.009

3.303 ± 0.014

6.408 ± 0.029

3.924 ± 0.018

6.665 ± 0.025

7.948 ± 0.029

5.738 ± 0.017

6.191 ± 0.023

1.441 ± 0.009

2.582 ± 0.013
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski