Amino acid dipepetide frequency for Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.915AlaAla: 6.915 ± 0.05	1.415AlaCys: 1.415 ± 0.015	2.836AlaAsp: 2.836 ± 0.019	4.741AlaGlu: 4.741 ± 0.033	2.773AlaPhe: 2.773 ± 0.023	4.837AlaGly: 4.837 ± 0.038	1.583AlaHis: 1.583 ± 0.014	2.742AlaIle: 2.742 ± 0.019	3.376AlaLys: 3.376 ± 0.025	7.228AlaLeu: 7.228 ± 0.039	1.467AlaMet: 1.467 ± 0.014	1.966AlaAsn: 1.966 ± 0.016	4.28AlaPro: 4.28 ± 0.039	3.224AlaGln: 3.224 ± 0.023	3.716AlaArg: 3.716 ± 0.027	5.736AlaSer: 5.736 ± 0.033	3.629AlaThr: 3.629 ± 0.028	4.677AlaVal: 4.677 ± 0.027	0.832AlaTrp: 0.832 ± 0.012	1.524AlaTyr: 1.524 ± 0.014	0.0AlaXaa: 0.0 ± 0.0
Cys	1.279CysAla: 1.279 ± 0.014	0.718CysCys: 0.718 ± 0.019	1.019CysAsp: 1.019 ± 0.015	1.354CysGlu: 1.354 ± 0.021	0.862CysPhe: 0.862 ± 0.011	1.986CysGly: 1.986 ± 0.03	0.679CysHis: 0.679 ± 0.01	0.938CysIle: 0.938 ± 0.012	1.222CysLys: 1.222 ± 0.017	2.206CysLeu: 2.206 ± 0.021	0.42CysMet: 0.42 ± 0.006	0.864CysAsn: 0.864 ± 0.013	1.421CysPro: 1.421 ± 0.02	1.121CysGln: 1.121 ± 0.016	1.333CysArg: 1.333 ± 0.015	2.048CysSer: 2.048 ± 0.02	1.12CysThr: 1.12 ± 0.014	1.306CysVal: 1.306 ± 0.016	0.303CysTrp: 0.303 ± 0.006	0.603CysTyr: 0.603 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	2.809AspAla: 2.809 ± 0.021	1.074AspCys: 1.074 ± 0.014	2.526AspAsp: 2.526 ± 0.021	3.357AspGlu: 3.357 ± 0.023	2.108AspPhe: 2.108 ± 0.019	3.204AspGly: 3.204 ± 0.027	1.121AspHis: 1.121 ± 0.013	2.54AspIle: 2.54 ± 0.019	2.452AspLys: 2.452 ± 0.019	4.897AspLeu: 4.897 ± 0.03	1.085AspMet: 1.085 ± 0.011	1.636AspAsn: 1.636 ± 0.016	2.89AspPro: 2.89 ± 0.022	1.777AspGln: 1.777 ± 0.014	2.385AspArg: 2.385 ± 0.018	4.126AspSer: 4.126 ± 0.027	2.448AspThr: 2.448 ± 0.017	3.007AspVal: 3.007 ± 0.027	0.627AspTrp: 0.627 ± 0.008	1.438AspTyr: 1.438 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	5.281GluAla: 5.281 ± 0.035	1.636GluCys: 1.636 ± 0.034	4.398GluAsp: 4.398 ± 0.026	7.973GluGlu: 7.973 ± 0.063	2.032GluPhe: 2.032 ± 0.015	4.167GluGly: 4.167 ± 0.027	1.495GluHis: 1.495 ± 0.013	3.092GluIle: 3.092 ± 0.027	5.502GluLys: 5.502 ± 0.045	6.397GluLeu: 6.397 ± 0.038	1.645GluMet: 1.645 ± 0.014	3.121GluAsn: 3.121 ± 0.023	3.308GluPro: 3.308 ± 0.033	3.103GluGln: 3.103 ± 0.028	3.983GluArg: 3.983 ± 0.035	4.304GluSer: 4.304 ± 0.029	3.39GluThr: 3.39 ± 0.025	4.148GluVal: 4.148 ± 0.03	0.702GluTrp: 0.702 ± 0.009	1.556GluTyr: 1.556 ± 0.019	0.001GluXaa: 0.001 ± 0.0
Phe	1.977PheAla: 1.977 ± 0.016	0.966PheCys: 0.966 ± 0.01	1.634PheAsp: 1.634 ± 0.014	1.983PheGlu: 1.983 ± 0.014	1.62PhePhe: 1.62 ± 0.018	2.217PheGly: 2.217 ± 0.021	1.059PheHis: 1.059 ± 0.011	1.834PheIle: 1.834 ± 0.018	1.812PheLys: 1.812 ± 0.017	4.199PheLeu: 4.199 ± 0.031	0.771PheMet: 0.771 ± 0.01	1.361PheAsn: 1.361 ± 0.016	2.031PhePro: 2.031 ± 0.018	1.84PheGln: 1.84 ± 0.015	2.01PheArg: 2.01 ± 0.02	3.521PheSer: 3.521 ± 0.025	2.076PheThr: 2.076 ± 0.016	2.131PheVal: 2.131 ± 0.018	0.508PheTrp: 0.508 ± 0.007	1.21PheTyr: 1.21 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	4.585GlyAla: 4.585 ± 0.035	1.334GlyCys: 1.334 ± 0.015	3.106GlyAsp: 3.106 ± 0.027	4.308GlyGlu: 4.308 ± 0.039	2.437GlyPhe: 2.437 ± 0.024	5.138GlyGly: 5.138 ± 0.051	1.699GlyHis: 1.699 ± 0.017	2.743GlyIle: 2.743 ± 0.022	3.965GlyLys: 3.965 ± 0.027	5.994GlyLeu: 5.994 ± 0.043	1.273GlyMet: 1.273 ± 0.014	2.34GlyAsn: 2.34 ± 0.019	4.383GlyPro: 4.383 ± 0.063	2.776GlyGln: 2.776 ± 0.027	3.729GlyArg: 3.729 ± 0.024	5.82GlySer: 5.82 ± 0.042	3.58GlyThr: 3.58 ± 0.03	3.533GlyVal: 3.533 ± 0.027	0.786GlyTrp: 0.786 ± 0.01	1.727GlyTyr: 1.727 ± 0.017	0.001GlyXaa: 0.001 ± 0.0
His	1.327HisAla: 1.327 ± 0.012	0.743HisCys: 0.743 ± 0.01	0.862HisAsp: 0.862 ± 0.01	1.324HisGlu: 1.324 ± 0.012	1.103HisPhe: 1.103 ± 0.012	1.547HisGly: 1.547 ± 0.018	0.923HisHis: 0.923 ± 0.015	1.219HisIle: 1.219 ± 0.013	1.327HisLys: 1.327 ± 0.017	2.99HisLeu: 2.99 ± 0.021	0.595HisMet: 0.595 ± 0.008	0.874HisAsn: 0.874 ± 0.011	1.654HisPro: 1.654 ± 0.015	1.421HisGln: 1.421 ± 0.019	1.61HisArg: 1.61 ± 0.014	2.342HisSer: 2.342 ± 0.022	1.711HisThr: 1.711 ± 0.025	1.472HisVal: 1.472 ± 0.013	0.367HisTrp: 0.367 ± 0.006	0.804HisTyr: 0.804 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	2.496IleAla: 2.496 ± 0.017	1.104IleCys: 1.104 ± 0.011	1.951IleAsp: 1.951 ± 0.018	2.487IleGlu: 2.487 ± 0.023	1.908IlePhe: 1.908 ± 0.016	2.155IleGly: 2.155 ± 0.016	1.512IleHis: 1.512 ± 0.021	2.363IleIle: 2.363 ± 0.02	2.57IleLys: 2.57 ± 0.025	4.591IleLeu: 4.591 ± 0.031	0.98IleMet: 0.98 ± 0.009	1.776IleAsn: 1.776 ± 0.015	2.59IlePro: 2.59 ± 0.019	2.248IleGln: 2.248 ± 0.019	2.329IleArg: 2.329 ± 0.019	3.683IleSer: 3.683 ± 0.024	2.542IleThr: 2.542 ± 0.028	2.452IleVal: 2.452 ± 0.022	0.516IleTrp: 0.516 ± 0.008	1.401IleTyr: 1.401 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	4.119LysAla: 4.119 ± 0.028	1.276LysCys: 1.276 ± 0.021	3.058LysAsp: 3.058 ± 0.026	5.082LysGlu: 5.082 ± 0.042	1.714LysPhe: 1.714 ± 0.016	3.236LysGly: 3.236 ± 0.035	1.414LysHis: 1.414 ± 0.014	2.795LysIle: 2.795 ± 0.024	4.735LysLys: 4.735 ± 0.04	5.11LysLeu: 5.11 ± 0.033	1.452LysMet: 1.452 ± 0.017	2.384LysAsn: 2.384 ± 0.019	3.281LysPro: 3.281 ± 0.033	2.567LysGln: 2.567 ± 0.022	3.298LysArg: 3.298 ± 0.023	3.903LysSer: 3.903 ± 0.023	3.112LysThr: 3.112 ± 0.02	3.449LysVal: 3.449 ± 0.036	0.603LysTrp: 0.603 ± 0.009	1.553LysTyr: 1.553 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.901LeuAla: 6.901 ± 0.038	2.228LeuCys: 2.228 ± 0.022	4.658LeuAsp: 4.658 ± 0.028	7.172LeuGlu: 7.172 ± 0.043	3.417LeuPhe: 3.417 ± 0.025	6.008LeuGly: 6.008 ± 0.038	2.744LeuHis: 2.744 ± 0.02	3.907LeuIle: 3.907 ± 0.024	5.719LeuLys: 5.719 ± 0.037	11.066LeuLeu: 11.066 ± 0.061	1.992LeuMet: 1.992 ± 0.015	3.481LeuAsn: 3.481 ± 0.023	6.074LeuPro: 6.074 ± 0.038	5.798LeuGln: 5.798 ± 0.038	5.977LeuArg: 5.977 ± 0.037	8.074LeuSer: 8.074 ± 0.034	5.178LeuThr: 5.178 ± 0.027	5.579LeuVal: 5.579 ± 0.03	1.179LeuTrp: 1.179 ± 0.012	2.566LeuTyr: 2.566 ± 0.021	0.001LeuXaa: 0.001 ± 0.0
Met	1.93MetAla: 1.93 ± 0.016	0.392MetCys: 0.392 ± 0.008	1.219MetAsp: 1.219 ± 0.013	1.828MetGlu: 1.828 ± 0.013	0.723MetPhe: 0.723 ± 0.009	1.279MetGly: 1.279 ± 0.014	0.464MetHis: 0.464 ± 0.007	0.829MetIle: 0.829 ± 0.01	1.419MetLys: 1.419 ± 0.014	1.953MetLeu: 1.953 ± 0.016	0.545MetMet: 0.545 ± 0.009	0.879MetAsn: 0.879 ± 0.012	1.087MetPro: 1.087 ± 0.016	0.899MetGln: 0.899 ± 0.012	1.025MetArg: 1.025 ± 0.01	1.526MetSer: 1.526 ± 0.014	1.11MetThr: 1.11 ± 0.012	1.336MetVal: 1.336 ± 0.011	0.244MetTrp: 0.244 ± 0.005	0.574MetTyr: 0.574 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	1.997AsnAla: 1.997 ± 0.018	0.854AsnCys: 0.854 ± 0.013	1.473AsnAsp: 1.473 ± 0.014	2.212AsnGlu: 2.212 ± 0.019	1.483AsnPhe: 1.483 ± 0.014	2.365AsnGly: 2.365 ± 0.023	0.945AsnHis: 0.945 ± 0.01	2.07AsnIle: 2.07 ± 0.018	2.182AsnLys: 2.182 ± 0.02	3.748AsnLeu: 3.748 ± 0.024	0.891AsnMet: 0.891 ± 0.009	1.518AsnAsn: 1.518 ± 0.017	2.173AsnPro: 2.173 ± 0.016	1.645AsnGln: 1.645 ± 0.018	1.841AsnArg: 1.841 ± 0.015	3.097AsnSer: 3.097 ± 0.022	1.926AsnThr: 1.926 ± 0.019	2.178AsnVal: 2.178 ± 0.018	0.454AsnTrp: 0.454 ± 0.007	1.116AsnTyr: 1.116 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	4.923ProAla: 4.923 ± 0.037	1.177ProCys: 1.177 ± 0.017	2.778ProAsp: 2.778 ± 0.022	4.531ProGlu: 4.531 ± 0.039	1.95ProPhe: 1.95 ± 0.015	5.389ProGly: 5.389 ± 0.081	1.446ProHis: 1.446 ± 0.016	1.867ProIle: 1.867 ± 0.018	2.824ProLys: 2.824 ± 0.036	5.317ProLeu: 5.317 ± 0.028	1.036ProMet: 1.036 ± 0.013	1.78ProAsn: 1.78 ± 0.016	6.114ProPro: 6.114 ± 0.072	2.859ProGln: 2.859 ± 0.023	3.438ProArg: 3.438 ± 0.027	5.637ProSer: 5.637 ± 0.044	3.111ProThr: 3.111 ± 0.033	3.819ProVal: 3.819 ± 0.033	0.714ProTrp: 0.714 ± 0.01	1.673ProTyr: 1.673 ± 0.025	0.001ProXaa: 0.001 ± 0.0
Gln	3.53GlnAla: 3.53 ± 0.029	0.975GlnCys: 0.975 ± 0.014	2.32GlnAsp: 2.32 ± 0.017	3.932GlnGlu: 3.932 ± 0.03	1.351GlnPhe: 1.351 ± 0.012	2.892GlnGly: 2.892 ± 0.026	1.307GlnHis: 1.307 ± 0.015	1.954GlnIle: 1.954 ± 0.016	2.952GlnLys: 2.952 ± 0.027	4.752GlnLeu: 4.752 ± 0.034	1.08GlnMet: 1.08 ± 0.01	1.848GlnAsn: 1.848 ± 0.015	2.815GlnPro: 2.815 ± 0.025	3.018GlnGln: 3.018 ± 0.044	3.022GlnArg: 3.022 ± 0.023	3.113GlnSer: 3.113 ± 0.024	2.28GlnThr: 2.28 ± 0.017	2.789GlnVal: 2.789 ± 0.02	0.546GlnTrp: 0.546 ± 0.008	1.118GlnTyr: 1.118 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	3.905ArgAla: 3.905 ± 0.027	1.242ArgCys: 1.242 ± 0.016	2.716ArgAsp: 2.716 ± 0.021	3.976ArgGlu: 3.976 ± 0.029	1.869ArgPhe: 1.869 ± 0.016	3.647ArgGly: 3.647 ± 0.036	1.602ArgHis: 1.602 ± 0.015	2.46ArgIle: 2.46 ± 0.019	3.706ArgLys: 3.706 ± 0.023	5.453ArgLeu: 5.453 ± 0.033	1.156ArgMet: 1.156 ± 0.012	2.117ArgAsn: 2.117 ± 0.014	3.284ArgPro: 3.284 ± 0.024	2.595ArgGln: 2.595 ± 0.022	4.382ArgArg: 4.382 ± 0.037	4.204ArgSer: 4.204 ± 0.038	2.79ArgThr: 2.79 ± 0.019	3.15ArgVal: 3.15 ± 0.026	0.705ArgTrp: 0.705 ± 0.01	1.455ArgTyr: 1.455 ± 0.013	0.0ArgXaa: 0.0 ± 0.0
Ser	5.272SerAla: 5.272 ± 0.031	1.925SerCys: 1.925 ± 0.023	3.774SerAsp: 3.774 ± 0.027	5.135SerGlu: 5.135 ± 0.036	3.113SerPhe: 3.113 ± 0.02	5.646SerGly: 5.646 ± 0.037	2.185SerHis: 2.185 ± 0.018	3.178SerIle: 3.178 ± 0.02	4.045SerLys: 4.045 ± 0.027	8.264SerLeu: 8.264 ± 0.036	1.574SerMet: 1.574 ± 0.015	2.683SerAsn: 2.683 ± 0.021	5.936SerPro: 5.936 ± 0.048	3.877SerGln: 3.877 ± 0.026	4.52SerArg: 4.52 ± 0.034	9.325SerSer: 9.325 ± 0.067	4.494SerThr: 4.494 ± 0.051	4.848SerVal: 4.848 ± 0.026	1.098SerTrp: 1.098 ± 0.014	2.091SerTyr: 2.091 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	3.753ThrAla: 3.753 ± 0.025	1.341ThrCys: 1.341 ± 0.019	2.39ThrAsp: 2.39 ± 0.018	3.497ThrGlu: 3.497 ± 0.026	2.159ThrPhe: 2.159 ± 0.016	3.749ThrGly: 3.749 ± 0.049	1.394ThrHis: 1.394 ± 0.019	2.374ThrIle: 2.374 ± 0.021	2.634ThrLys: 2.634 ± 0.025	5.365ThrLeu: 5.365 ± 0.03	1.097ThrMet: 1.097 ± 0.01	1.706ThrAsn: 1.706 ± 0.014	3.577ThrPro: 3.577 ± 0.043	2.311ThrGln: 2.311 ± 0.017	2.479ThrArg: 2.479 ± 0.018	4.626ThrSer: 4.626 ± 0.041	3.141ThrThr: 3.141 ± 0.066	3.826ThrVal: 3.826 ± 0.032	0.697ThrTrp: 0.697 ± 0.011	1.417ThrTyr: 1.417 ± 0.012	0.001ThrXaa: 0.001 ± 0.0
Val	4.278ValAla: 4.278 ± 0.025	1.46ValCys: 1.46 ± 0.015	2.875ValAsp: 2.875 ± 0.024	3.791ValGlu: 3.791 ± 0.028	2.438ValPhe: 2.438 ± 0.021	3.38ValGly: 3.38 ± 0.021	1.579ValHis: 1.579 ± 0.014	2.852ValIle: 2.852 ± 0.022	3.308ValLys: 3.308 ± 0.029	6.251ValLeu: 6.251 ± 0.032	1.3ValMet: 1.3 ± 0.013	2.204ValAsn: 2.204 ± 0.018	3.64ValPro: 3.64 ± 0.037	2.715ValGln: 2.715 ± 0.018	2.999ValArg: 2.999 ± 0.021	4.826ValSer: 4.826 ± 0.027	3.76ValThr: 3.76 ± 0.04	3.952ValVal: 3.952 ± 0.027	0.718ValTrp: 0.718 ± 0.009	1.613ValTyr: 1.613 ± 0.014	0.001ValXaa: 0.001 ± 0.0
Trp	0.822TrpAla: 0.822 ± 0.01	0.249TrpCys: 0.249 ± 0.006	0.651TrpAsp: 0.651 ± 0.009	0.829TrpGlu: 0.829 ± 0.011	0.454TrpPhe: 0.454 ± 0.007	0.753TrpGly: 0.753 ± 0.012	0.31TrpHis: 0.31 ± 0.007	0.549TrpIle: 0.549 ± 0.009	0.821TrpLys: 0.821 ± 0.01	1.236TrpLeu: 1.236 ± 0.013	0.31TrpMet: 0.31 ± 0.006	0.54TrpAsn: 0.54 ± 0.008	0.536TrpPro: 0.536 ± 0.009	0.541TrpGln: 0.541 ± 0.008	0.75TrpArg: 0.75 ± 0.009	0.878TrpSer: 0.878 ± 0.011	0.674TrpThr: 0.674 ± 0.01	0.718TrpVal: 0.718 ± 0.009	0.194TrpTrp: 0.194 ± 0.005	0.353TrpTyr: 0.353 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.398TyrAla: 1.398 ± 0.014	0.691TyrCys: 0.691 ± 0.009	1.264TyrAsp: 1.264 ± 0.015	1.721TyrGlu: 1.721 ± 0.016	1.244TyrPhe: 1.244 ± 0.013	1.662TyrGly: 1.662 ± 0.015	0.754TyrHis: 0.754 ± 0.009	1.351TyrIle: 1.351 ± 0.013	1.568TyrLys: 1.568 ± 0.023	2.704TyrLeu: 2.704 ± 0.017	0.591TyrMet: 0.591 ± 0.008	1.09TyrAsn: 1.09 ± 0.012	1.306TyrPro: 1.306 ± 0.013	1.258TyrGln: 1.258 ± 0.012	1.592TyrArg: 1.592 ± 0.015	2.193TyrSer: 2.193 ± 0.019	1.461TyrThr: 1.461 ± 0.014	1.569TyrVal: 1.569 ± 0.015	0.374TyrTrp: 0.374 ± 0.008	0.953TyrTyr: 0.953 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.011XaaXaa: 0.011 ± 0.002

Statistics based on 19229 proteins (10437685 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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