Amino acid dipepetide frequency for Wenling crustacean virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.171AlaAla: 7.171 ± 1.602
1.63AlaCys: 1.63 ± 0.315
4.563AlaAsp: 4.563 ± 1.369
1.63AlaGlu: 1.63 ± 0.851
0.978AlaPhe: 0.978 ± 0.025
1.956AlaGly: 1.956 ± 1.022
0.978AlaHis: 0.978 ± 1.097
3.911AlaIle: 3.911 ± 0.637
4.889AlaLys: 4.889 ± 0.126
5.867AlaLeu: 5.867 ± 1.457
1.956AlaMet: 1.956 ± 0.486
1.956AlaAsn: 1.956 ± 0.05
2.934AlaPro: 2.934 ± 1.148
3.585AlaGln: 3.585 ± 0.265
3.911AlaArg: 3.911 ± 0.971
6.519AlaSer: 6.519 ± 0.725
4.889AlaThr: 4.889 ± 0.946
4.563AlaVal: 4.563 ± 0.24
0.652AlaTrp: 0.652 ± 0.341
2.608AlaTyr: 2.608 ± 0.29
0.0AlaXaa: 0.0 ± 0.0
Cys
0.652CysAla: 0.652 ± 0.732
0.652CysCys: 0.652 ± 0.196
1.63CysAsp: 1.63 ± 0.315
1.304CysGlu: 1.304 ± 0.145
1.63CysPhe: 1.63 ± 0.851
0.326CysGly: 0.326 ± 0.17
0.326CysHis: 0.326 ± 0.366
0.652CysIle: 0.652 ± 0.341
1.63CysLys: 1.63 ± 0.315
0.326CysLeu: 0.326 ± 0.17
0.0CysMet: 0.0 ± 0.0
0.652CysAsn: 0.652 ± 0.196
0.978CysPro: 0.978 ± 0.561
0.0CysGln: 0.0 ± 0.0
1.304CysArg: 1.304 ± 0.681
1.956CysSer: 1.956 ± 0.486
0.0CysThr: 0.0 ± 0.0
1.304CysVal: 1.304 ± 0.681
1.304CysTrp: 1.304 ± 0.681
0.326CysTyr: 0.326 ± 0.17
0.0CysXaa: 0.0 ± 0.0
Asp
3.259AspAla: 3.259 ± 0.095
0.978AspCys: 0.978 ± 0.511
5.541AspAsp: 5.541 ± 1.286
3.911AspGlu: 3.911 ± 0.637
4.237AspPhe: 4.237 ± 0.069
2.934AspGly: 2.934 ± 0.996
0.652AspHis: 0.652 ± 0.341
3.585AspIle: 3.585 ± 1.879
3.911AspLys: 3.911 ± 0.435
6.845AspLeu: 6.845 ± 0.359
1.956AspMet: 1.956 ± 0.486
2.608AspAsn: 2.608 ± 0.246
3.259AspPro: 3.259 ± 0.095
1.304AspGln: 1.304 ± 0.145
1.956AspArg: 1.956 ± 0.05
3.911AspSer: 3.911 ± 1.173
3.911AspThr: 3.911 ± 0.637
4.889AspVal: 4.889 ± 0.662
1.63AspTrp: 1.63 ± 0.757
2.934AspTyr: 2.934 ± 0.46
0.0AspXaa: 0.0 ± 0.0
Glu
5.215GluAla: 5.215 ± 1.652
1.304GluCys: 1.304 ± 0.145
2.608GluAsp: 2.608 ± 0.246
4.237GluGlu: 4.237 ± 1.141
1.956GluPhe: 1.956 ± 0.486
4.237GluGly: 4.237 ± 1.003
0.326GluHis: 0.326 ± 0.366
2.934GluIle: 2.934 ± 0.46
4.237GluLys: 4.237 ± 1.677
5.541GluLeu: 5.541 ± 1.286
2.282GluMet: 2.282 ± 0.656
4.889GluAsn: 4.889 ± 0.41
1.63GluPro: 1.63 ± 0.757
5.867GluGln: 5.867 ± 0.385
1.304GluArg: 1.304 ± 0.391
4.563GluSer: 4.563 ± 0.776
5.215GluThr: 5.215 ± 0.044
3.585GluVal: 3.585 ± 0.265
1.63GluTrp: 1.63 ± 0.221
2.608GluTyr: 2.608 ± 0.782
0.0GluXaa: 0.0 ± 0.0
Phe
1.63PheAla: 1.63 ± 0.315
0.0PheCys: 0.0 ± 0.0
2.282PheAsp: 2.282 ± 0.12
2.934PheGlu: 2.934 ± 0.076
0.652PhePhe: 0.652 ± 0.196
2.282PheGly: 2.282 ± 0.656
0.978PheHis: 0.978 ± 0.025
1.956PheIle: 1.956 ± 0.05
1.63PheLys: 1.63 ± 0.221
4.237PheLeu: 4.237 ± 1.141
1.956PheMet: 1.956 ± 0.486
0.652PheAsn: 0.652 ± 0.196
2.608PhePro: 2.608 ± 0.826
2.282PheGln: 2.282 ± 0.12
1.956PheArg: 1.956 ± 0.05
2.934PheSer: 2.934 ± 0.076
4.563PheThr: 4.563 ± 0.296
3.259PheVal: 3.259 ± 0.631
0.978PheTrp: 0.978 ± 0.561
0.978PheTyr: 0.978 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
3.259GlyAla: 3.259 ± 0.095
0.326GlyCys: 0.326 ± 0.366
3.585GlyAsp: 3.585 ± 1.337
3.259GlyGlu: 3.259 ± 0.631
1.304GlyPhe: 1.304 ± 0.391
1.304GlyGly: 1.304 ± 0.391
0.652GlyHis: 0.652 ± 0.341
3.585GlyIle: 3.585 ± 0.801
4.237GlyLys: 4.237 ± 0.605
3.911GlyLeu: 3.911 ± 0.435
0.978GlyMet: 0.978 ± 0.511
3.911GlyAsn: 3.911 ± 0.435
2.608GlyPro: 2.608 ± 1.318
1.956GlyGln: 1.956 ± 0.05
1.304GlyArg: 1.304 ± 0.145
2.934GlySer: 2.934 ± 0.076
4.563GlyThr: 4.563 ± 1.369
2.608GlyVal: 2.608 ± 0.246
0.0GlyTrp: 0.0 ± 0.0
1.304GlyTyr: 1.304 ± 0.391
0.0GlyXaa: 0.0 ± 0.0
His
1.304HisAla: 1.304 ± 0.681
0.326HisCys: 0.326 ± 0.17
0.978HisAsp: 0.978 ± 0.511
1.956HisGlu: 1.956 ± 0.486
0.652HisPhe: 0.652 ± 0.341
1.63HisGly: 1.63 ± 0.315
0.652HisHis: 0.652 ± 0.732
0.978HisIle: 0.978 ± 0.025
0.652HisLys: 0.652 ± 0.196
2.608HisLeu: 2.608 ± 0.246
1.956HisMet: 1.956 ± 0.587
0.652HisAsn: 0.652 ± 0.196
1.304HisPro: 1.304 ± 0.927
0.326HisGln: 0.326 ± 0.17
0.978HisArg: 0.978 ± 0.561
0.978HisSer: 0.978 ± 0.561
0.652HisThr: 0.652 ± 0.196
1.63HisVal: 1.63 ± 0.315
0.978HisTrp: 0.978 ± 0.561
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.259IleAla: 3.259 ± 0.095
0.326IleCys: 0.326 ± 0.17
3.259IleAsp: 3.259 ± 2.05
2.608IleGlu: 2.608 ± 0.246
1.304IlePhe: 1.304 ± 0.391
3.259IleGly: 3.259 ± 0.631
1.956IleHis: 1.956 ± 0.05
2.608IleIle: 2.608 ± 0.29
3.585IleLys: 3.585 ± 0.801
4.237IleLeu: 4.237 ± 0.605
0.326IleMet: 0.326 ± 0.17
1.956IleAsn: 1.956 ± 1.022
2.934IlePro: 2.934 ± 1.148
3.585IleGln: 3.585 ± 0.271
3.585IleArg: 3.585 ± 0.265
2.608IleSer: 2.608 ± 0.29
4.889IleThr: 4.889 ± 0.662
5.541IleVal: 5.541 ± 0.214
1.304IleTrp: 1.304 ± 0.681
0.978IleTyr: 0.978 ± 0.561
0.0IleXaa: 0.0 ± 0.0
Lys
4.237LysAla: 4.237 ± 1.141
0.326LysCys: 0.326 ± 0.17
3.259LysAsp: 3.259 ± 0.631
4.889LysGlu: 4.889 ± 2.554
2.934LysPhe: 2.934 ± 0.46
3.911LysGly: 3.911 ± 0.101
1.304LysHis: 1.304 ± 0.681
3.911LysIle: 3.911 ± 0.101
4.563LysLys: 4.563 ± 0.776
4.237LysLeu: 4.237 ± 0.605
1.956LysMet: 1.956 ± 0.486
1.304LysAsn: 1.304 ± 0.145
2.608LysPro: 2.608 ± 0.782
0.978LysGln: 0.978 ± 0.561
6.193LysArg: 6.193 ± 1.091
4.237LysSer: 4.237 ± 2.213
3.585LysThr: 3.585 ± 1.337
4.889LysVal: 4.889 ± 0.662
0.652LysTrp: 0.652 ± 0.732
2.608LysTyr: 2.608 ± 0.246
0.0LysXaa: 0.0 ± 0.0
Leu
3.259LeuAla: 3.259 ± 1.167
1.63LeuCys: 1.63 ± 0.851
7.823LeuAsp: 7.823 ± 0.87
5.541LeuGlu: 5.541 ± 1.822
6.193LeuPhe: 6.193 ± 0.019
4.237LeuGly: 4.237 ± 0.605
1.304LeuHis: 1.304 ± 0.681
2.934LeuIle: 2.934 ± 0.996
5.541LeuLys: 5.541 ± 0.75
5.215LeuLeu: 5.215 ± 1.652
2.282LeuMet: 2.282 ± 0.416
4.563LeuAsn: 4.563 ± 0.296
2.934LeuPro: 2.934 ± 1.148
3.585LeuGln: 3.585 ± 0.807
7.823LeuArg: 7.823 ± 0.202
4.889LeuSer: 4.889 ± 0.41
4.563LeuThr: 4.563 ± 1.312
3.585LeuVal: 3.585 ± 0.271
1.63LeuTrp: 1.63 ± 0.315
2.934LeuTyr: 2.934 ± 1.684
0.0LeuXaa: 0.0 ± 0.0
Met
1.304MetAla: 1.304 ± 0.145
1.956MetCys: 1.956 ± 0.486
1.956MetAsp: 1.956 ± 0.486
2.934MetGlu: 2.934 ± 0.46
0.978MetPhe: 0.978 ± 0.511
0.652MetGly: 0.652 ± 0.341
0.326MetHis: 0.326 ± 0.17
0.978MetIle: 0.978 ± 0.025
1.63MetLys: 1.63 ± 0.851
2.608MetLeu: 2.608 ± 0.826
0.326MetMet: 0.326 ± 0.17
1.63MetAsn: 1.63 ± 0.757
0.978MetPro: 0.978 ± 0.561
0.326MetGln: 0.326 ± 0.17
1.956MetArg: 1.956 ± 0.587
1.63MetSer: 1.63 ± 0.221
4.563MetThr: 4.563 ± 0.776
0.978MetVal: 0.978 ± 0.025
0.0MetTrp: 0.0 ± 0.0
1.304MetTyr: 1.304 ± 0.927
0.0MetXaa: 0.0 ± 0.0
Asn
3.911AsnAla: 3.911 ± 0.101
0.978AsnCys: 0.978 ± 0.025
3.585AsnAsp: 3.585 ± 0.265
1.63AsnGlu: 1.63 ± 1.293
1.63AsnPhe: 1.63 ± 0.757
2.934AsnGly: 2.934 ± 0.076
1.304AsnHis: 1.304 ± 0.391
1.956AsnIle: 1.956 ± 0.486
3.585AsnLys: 3.585 ± 0.801
4.889AsnLeu: 4.889 ± 0.946
1.63AsnMet: 1.63 ± 0.315
0.978AsnAsn: 0.978 ± 0.025
4.237AsnPro: 4.237 ± 0.467
0.978AsnGln: 0.978 ± 0.511
1.63AsnArg: 1.63 ± 0.221
3.259AsnSer: 3.259 ± 0.442
3.585AsnThr: 3.585 ± 0.807
2.934AsnVal: 2.934 ± 1.684
0.326AsnTrp: 0.326 ± 0.366
2.282AsnTyr: 2.282 ± 0.416
0.0AsnXaa: 0.0 ± 0.0
Pro
3.259ProAla: 3.259 ± 1.167
0.978ProCys: 0.978 ± 0.561
3.259ProAsp: 3.259 ± 0.442
3.911ProGlu: 3.911 ± 0.637
0.326ProPhe: 0.326 ± 0.17
2.608ProGly: 2.608 ± 0.246
0.978ProHis: 0.978 ± 0.561
1.956ProIle: 1.956 ± 0.05
1.304ProLys: 1.304 ± 0.145
3.911ProLeu: 3.911 ± 2.245
1.63ProMet: 1.63 ± 0.221
2.282ProAsn: 2.282 ± 0.952
2.282ProPro: 2.282 ± 1.488
0.978ProGln: 0.978 ± 0.561
2.282ProArg: 2.282 ± 0.12
3.911ProSer: 3.911 ± 1.709
5.215ProThr: 5.215 ± 2.636
3.259ProVal: 3.259 ± 0.442
0.652ProTrp: 0.652 ± 0.196
1.63ProTyr: 1.63 ± 0.757
0.0ProXaa: 0.0 ± 0.0
Gln
2.934GlnAla: 2.934 ± 0.46
0.652GlnCys: 0.652 ± 0.341
1.304GlnAsp: 1.304 ± 0.145
3.585GlnGlu: 3.585 ± 0.265
0.978GlnPhe: 0.978 ± 0.511
2.282GlnGly: 2.282 ± 0.952
0.978GlnHis: 0.978 ± 0.511
2.608GlnIle: 2.608 ± 0.782
1.956GlnLys: 1.956 ± 0.486
3.259GlnLeu: 3.259 ± 0.442
0.978GlnMet: 0.978 ± 0.158
1.956GlnAsn: 1.956 ± 0.486
0.978GlnPro: 0.978 ± 0.025
0.652GlnGln: 0.652 ± 0.341
1.304GlnArg: 1.304 ± 0.145
3.259GlnSer: 3.259 ± 0.978
1.304GlnThr: 1.304 ± 0.145
3.911GlnVal: 3.911 ± 1.709
0.652GlnTrp: 0.652 ± 0.732
1.63GlnTyr: 1.63 ± 0.315
0.0GlnXaa: 0.0 ± 0.0
Arg
1.956ArgAla: 1.956 ± 0.05
0.326ArgCys: 0.326 ± 0.366
2.608ArgAsp: 2.608 ± 0.246
1.304ArgGlu: 1.304 ± 0.681
2.934ArgPhe: 2.934 ± 0.46
0.326ArgGly: 0.326 ± 0.17
1.956ArgHis: 1.956 ± 0.05
3.911ArgIle: 3.911 ± 0.101
4.563ArgLys: 4.563 ± 0.24
3.911ArgLeu: 3.911 ± 0.637
1.304ArgMet: 1.304 ± 0.583
3.585ArgAsn: 3.585 ± 0.265
2.934ArgPro: 2.934 ± 0.996
2.934ArgGln: 2.934 ± 0.46
2.282ArgArg: 2.282 ± 0.12
4.563ArgSer: 4.563 ± 0.776
2.934ArgThr: 2.934 ± 1.532
3.585ArgVal: 3.585 ± 1.879
0.326ArgTrp: 0.326 ± 0.17
1.956ArgTyr: 1.956 ± 0.05
0.0ArgXaa: 0.0 ± 0.0
Ser
5.867SerAla: 5.867 ± 1.76
0.652SerCys: 0.652 ± 0.341
4.889SerAsp: 4.889 ± 1.198
7.171SerGlu: 7.171 ± 0.542
3.585SerPhe: 3.585 ± 0.801
3.585SerGly: 3.585 ± 1.343
2.608SerHis: 2.608 ± 1.318
4.889SerIle: 4.889 ± 0.946
3.911SerLys: 3.911 ± 1.507
5.215SerLeu: 5.215 ± 1.652
1.956SerMet: 1.956 ± 0.486
1.956SerAsn: 1.956 ± 0.05
2.934SerPro: 2.934 ± 0.46
1.304SerGln: 1.304 ± 0.681
3.259SerArg: 3.259 ± 0.095
5.867SerSer: 5.867 ± 1.993
6.519SerThr: 6.519 ± 1.955
2.934SerVal: 2.934 ± 0.612
0.326SerTrp: 0.326 ± 0.17
2.608SerTyr: 2.608 ± 0.826
0.0SerXaa: 0.0 ± 0.0
Thr
7.171ThrAla: 7.171 ± 1.079
2.282ThrCys: 2.282 ± 0.12
2.934ThrAsp: 2.934 ± 0.076
5.541ThrGlu: 5.541 ± 0.322
3.585ThrPhe: 3.585 ± 0.807
3.585ThrGly: 3.585 ± 0.265
2.282ThrHis: 2.282 ± 0.12
3.585ThrIle: 3.585 ± 0.271
2.934ThrLys: 2.934 ± 0.46
7.497ThrLeu: 7.497 ± 1.444
2.282ThrMet: 2.282 ± 0.12
3.585ThrAsn: 3.585 ± 1.343
4.237ThrPro: 4.237 ± 2.611
2.282ThrGln: 2.282 ± 0.656
2.934ThrArg: 2.934 ± 0.076
6.519ThrSer: 6.519 ± 0.347
6.519ThrThr: 6.519 ± 0.189
5.541ThrVal: 5.541 ± 0.75
0.326ThrTrp: 0.326 ± 0.17
0.978ThrTyr: 0.978 ± 0.025
0.0ThrXaa: 0.0 ± 0.0
Val
3.585ValAla: 3.585 ± 0.271
0.978ValCys: 0.978 ± 0.511
4.889ValAsp: 4.889 ± 1.198
5.215ValGlu: 5.215 ± 0.044
2.608ValPhe: 2.608 ± 0.246
3.585ValGly: 3.585 ± 0.271
0.0ValHis: 0.0 ± 0.0
4.563ValIle: 4.563 ± 0.296
4.889ValLys: 4.889 ± 0.41
3.911ValLeu: 3.911 ± 0.101
1.63ValMet: 1.63 ± 0.315
4.889ValAsn: 4.889 ± 0.126
1.956ValPro: 1.956 ± 0.587
3.585ValGln: 3.585 ± 2.951
2.282ValArg: 2.282 ± 0.656
5.215ValSer: 5.215 ± 0.492
5.541ValThr: 5.541 ± 3.002
4.237ValVal: 4.237 ± 0.605
1.63ValTrp: 1.63 ± 0.221
2.282ValTyr: 2.282 ± 0.12
0.0ValXaa: 0.0 ± 0.0
Trp
0.978TrpAla: 0.978 ± 0.025
0.0TrpCys: 0.0 ± 0.0
1.304TrpAsp: 1.304 ± 0.145
0.326TrpGlu: 0.326 ± 0.17
0.326TrpPhe: 0.326 ± 0.17
0.326TrpGly: 0.326 ± 0.17
0.326TrpHis: 0.326 ± 0.17
1.304TrpIle: 1.304 ± 0.391
2.282TrpLys: 2.282 ± 0.416
0.326TrpLeu: 0.326 ± 0.17
0.652TrpMet: 0.652 ± 0.196
1.63TrpAsn: 1.63 ± 0.757
0.0TrpPro: 0.0 ± 0.0
0.652TrpGln: 0.652 ± 0.196
1.304TrpArg: 1.304 ± 0.145
0.326TrpSer: 0.326 ± 0.17
1.304TrpThr: 1.304 ± 0.391
1.63TrpVal: 1.63 ± 0.757
0.0TrpTrp: 0.0 ± 0.0
0.652TrpTyr: 0.652 ± 0.196
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.934TyrAla: 2.934 ± 0.46
0.652TyrCys: 0.652 ± 0.341
1.956TyrAsp: 1.956 ± 0.05
2.282TyrGlu: 2.282 ± 0.12
1.956TyrPhe: 1.956 ± 0.486
1.63TyrGly: 1.63 ± 0.221
1.304TyrHis: 1.304 ± 0.145
1.304TyrIle: 1.304 ± 0.145
0.652TyrLys: 0.652 ± 0.196
3.911TyrLeu: 3.911 ± 0.435
0.652TyrMet: 0.652 ± 0.196
2.608TyrAsn: 2.608 ± 1.318
2.282TyrPro: 2.282 ± 0.952
0.0TyrGln: 0.0 ± 0.0
0.978TyrArg: 0.978 ± 0.561
1.956TyrSer: 1.956 ± 0.587
2.282TyrThr: 2.282 ± 0.12
2.608TyrVal: 2.608 ± 1.854
0.652TyrTrp: 0.652 ± 0.196
1.304TyrTyr: 1.304 ± 0.681
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3069 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski