Amino acid dipepetide frequency for Streptococcus satellite phage Javan441

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.499AlaCys: 0.499 ± 0.466
2.991AlaAsp: 2.991 ± 0.928
3.49AlaGlu: 3.49 ± 1.02
3.49AlaPhe: 3.49 ± 0.894
1.496AlaGly: 1.496 ± 1.178
0.0AlaHis: 0.0 ± 0.0
5.982AlaIle: 5.982 ± 1.523
4.487AlaLys: 4.487 ± 1.492
6.481AlaLeu: 6.481 ± 1.607
2.991AlaMet: 2.991 ± 1.139
0.997AlaAsn: 0.997 ± 0.783
1.994AlaPro: 1.994 ± 0.932
1.994AlaGln: 1.994 ± 0.937
2.991AlaArg: 2.991 ± 1.451
1.994AlaSer: 1.994 ± 0.973
2.991AlaThr: 2.991 ± 1.363
1.994AlaVal: 1.994 ± 0.769
0.0AlaTrp: 0.0 ± 0.0
1.496AlaTyr: 1.496 ± 0.872
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.499CysAsp: 0.499 ± 0.556
0.997CysGlu: 0.997 ± 0.503
0.0CysPhe: 0.0 ± 0.0
1.994CysGly: 1.994 ± 1.052
0.0CysHis: 0.0 ± 0.0
0.499CysIle: 0.499 ± 0.392
0.997CysLys: 0.997 ± 0.701
1.496CysLeu: 1.496 ± 1.036
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.499CysSer: 0.499 ± 0.484
0.499CysThr: 0.499 ± 0.466
0.997CysVal: 0.997 ± 0.932
0.0CysTrp: 0.0 ± 0.0
1.496CysTyr: 1.496 ± 0.928
0.0CysXaa: 0.0 ± 0.0
Asp
1.994AspAla: 1.994 ± 0.821
0.997AspCys: 0.997 ± 0.932
3.49AspAsp: 3.49 ± 1.334
3.988AspGlu: 3.988 ± 1.25
3.49AspPhe: 3.49 ± 1.118
1.994AspGly: 1.994 ± 0.986
0.0AspHis: 0.0 ± 0.0
6.979AspIle: 6.979 ± 1.652
6.979AspLys: 6.979 ± 2.153
5.982AspLeu: 5.982 ± 2.123
2.493AspMet: 2.493 ± 1.014
4.487AspAsn: 4.487 ± 1.278
0.997AspPro: 0.997 ± 0.607
1.496AspGln: 1.496 ± 0.827
2.991AspArg: 2.991 ± 0.825
1.994AspSer: 1.994 ± 0.973
1.994AspThr: 1.994 ± 0.975
0.997AspVal: 0.997 ± 0.702
0.997AspTrp: 0.997 ± 0.713
4.985AspTyr: 4.985 ± 1.896
0.0AspXaa: 0.0 ± 0.0
Glu
6.481GluAla: 6.481 ± 1.951
0.997GluCys: 0.997 ± 0.647
6.481GluAsp: 6.481 ± 1.872
6.481GluGlu: 6.481 ± 1.704
2.991GluPhe: 2.991 ± 1.201
1.496GluGly: 1.496 ± 0.739
0.997GluHis: 0.997 ± 0.543
2.991GluIle: 2.991 ± 1.0
8.475GluLys: 8.475 ± 1.554
12.463GluLeu: 12.463 ± 2.072
1.496GluMet: 1.496 ± 0.78
3.49GluAsn: 3.49 ± 1.568
1.994GluPro: 1.994 ± 0.807
2.991GluGln: 2.991 ± 1.27
4.487GluArg: 4.487 ± 1.003
1.496GluSer: 1.496 ± 0.671
1.496GluThr: 1.496 ± 0.901
3.49GluVal: 3.49 ± 1.229
0.997GluTrp: 0.997 ± 0.677
4.487GluTyr: 4.487 ± 1.472
0.0GluXaa: 0.0 ± 0.0
Phe
1.994PheAla: 1.994 ± 0.893
0.499PheCys: 0.499 ± 0.466
1.994PheAsp: 1.994 ± 0.866
4.985PheGlu: 4.985 ± 1.638
1.994PhePhe: 1.994 ± 1.077
1.994PheGly: 1.994 ± 1.209
1.496PheHis: 1.496 ± 1.025
3.49PheIle: 3.49 ± 1.201
4.487PheLys: 4.487 ± 1.732
1.994PheLeu: 1.994 ± 0.753
0.997PheMet: 0.997 ± 0.708
0.499PheAsn: 0.499 ± 0.505
1.496PhePro: 1.496 ± 1.034
0.499PheGln: 0.499 ± 0.459
2.493PheArg: 2.493 ± 1.086
1.994PheSer: 1.994 ± 1.071
1.994PheThr: 1.994 ± 0.878
0.997PheVal: 0.997 ± 1.01
0.0PheTrp: 0.0 ± 0.0
0.997PheTyr: 0.997 ± 0.578
0.0PheXaa: 0.0 ± 0.0
Gly
1.994GlyAla: 1.994 ± 0.847
1.496GlyCys: 1.496 ± 0.788
1.994GlyAsp: 1.994 ± 1.1
0.499GlyGlu: 0.499 ± 0.446
1.496GlyPhe: 1.496 ± 0.664
2.991GlyGly: 2.991 ± 0.894
0.997GlyHis: 0.997 ± 0.741
4.985GlyIle: 4.985 ± 1.072
4.487GlyLys: 4.487 ± 1.145
3.49GlyLeu: 3.49 ± 1.079
0.997GlyMet: 0.997 ± 0.726
2.991GlyAsn: 2.991 ± 1.091
0.0GlyPro: 0.0 ± 0.0
1.496GlyGln: 1.496 ± 0.876
2.991GlyArg: 2.991 ± 1.143
2.991GlySer: 2.991 ± 1.12
3.49GlyThr: 3.49 ± 1.27
3.988GlyVal: 3.988 ± 1.154
0.0GlyTrp: 0.0 ± 0.0
4.487GlyTyr: 4.487 ± 1.323
0.0GlyXaa: 0.0 ± 0.0
His
1.994HisAla: 1.994 ± 1.25
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.493HisGlu: 2.493 ± 0.995
0.499HisPhe: 0.499 ± 0.473
0.0HisGly: 0.0 ± 0.0
0.499HisHis: 0.499 ± 0.459
0.499HisIle: 0.499 ± 0.523
0.997HisLys: 0.997 ± 0.69
1.496HisLeu: 1.496 ± 0.647
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.499HisGln: 0.499 ± 0.413
0.997HisArg: 0.997 ± 0.726
0.997HisSer: 0.997 ± 0.659
1.496HisThr: 1.496 ± 0.809
0.997HisVal: 0.997 ± 0.648
0.0HisTrp: 0.0 ± 0.0
1.994HisTyr: 1.994 ± 1.08
0.0HisXaa: 0.0 ± 0.0
Ile
3.988IleAla: 3.988 ± 0.947
2.493IleCys: 2.493 ± 1.05
6.481IleAsp: 6.481 ± 1.833
2.493IleGlu: 2.493 ± 1.157
0.499IlePhe: 0.499 ± 0.588
4.487IleGly: 4.487 ± 1.577
1.496IleHis: 1.496 ± 0.845
4.487IleIle: 4.487 ± 1.199
9.472IleLys: 9.472 ± 2.208
7.478IleLeu: 7.478 ± 2.168
2.493IleMet: 2.493 ± 1.085
5.982IleAsn: 5.982 ± 1.428
3.49IlePro: 3.49 ± 1.029
0.997IleGln: 0.997 ± 0.648
1.994IleArg: 1.994 ± 1.154
5.484IleSer: 5.484 ± 1.653
6.481IleThr: 6.481 ± 1.949
2.991IleVal: 2.991 ± 0.928
0.0IleTrp: 0.0 ± 0.0
2.991IleTyr: 2.991 ± 0.952
0.0IleXaa: 0.0 ± 0.0
Lys
6.481LysAla: 6.481 ± 1.688
0.0LysCys: 0.0 ± 0.0
5.484LysAsp: 5.484 ± 1.378
8.475LysGlu: 8.475 ± 1.904
0.997LysPhe: 0.997 ± 0.677
3.49LysGly: 3.49 ± 1.153
2.493LysHis: 2.493 ± 1.076
6.481LysIle: 6.481 ± 1.692
11.964LysLys: 11.964 ± 3.049
11.964LysLeu: 11.964 ± 2.403
3.49LysMet: 3.49 ± 1.475
6.481LysAsn: 6.481 ± 1.697
2.493LysPro: 2.493 ± 0.915
5.484LysGln: 5.484 ± 1.865
8.973LysArg: 8.973 ± 1.976
4.487LysSer: 4.487 ± 1.254
4.487LysThr: 4.487 ± 1.488
4.487LysVal: 4.487 ± 1.002
0.499LysTrp: 0.499 ± 0.413
5.484LysTyr: 5.484 ± 1.701
0.0LysXaa: 0.0 ± 0.0
Leu
6.481LeuAla: 6.481 ± 1.763
0.0LeuCys: 0.0 ± 0.0
6.979LeuAsp: 6.979 ± 1.334
10.469LeuGlu: 10.469 ± 2.014
2.991LeuPhe: 2.991 ± 1.435
8.475LeuGly: 8.475 ± 1.727
1.496LeuHis: 1.496 ± 0.824
6.481LeuIle: 6.481 ± 1.719
9.97LeuLys: 9.97 ± 2.271
4.985LeuLeu: 4.985 ± 2.316
4.985LeuMet: 4.985 ± 1.242
7.478LeuAsn: 7.478 ± 1.381
2.493LeuPro: 2.493 ± 1.245
3.49LeuGln: 3.49 ± 1.287
4.487LeuArg: 4.487 ± 1.209
4.985LeuSer: 4.985 ± 0.93
6.481LeuThr: 6.481 ± 1.41
5.484LeuVal: 5.484 ± 1.756
2.493LeuTrp: 2.493 ± 1.049
1.994LeuTyr: 1.994 ± 0.704
0.0LeuXaa: 0.0 ± 0.0
Met
2.991MetAla: 2.991 ± 1.258
0.0MetCys: 0.0 ± 0.0
1.994MetAsp: 1.994 ± 1.286
2.991MetGlu: 2.991 ± 1.041
0.0MetPhe: 0.0 ± 0.0
0.499MetGly: 0.499 ± 0.446
0.0MetHis: 0.0 ± 0.0
0.997MetIle: 0.997 ± 0.891
4.487MetLys: 4.487 ± 1.655
1.994MetLeu: 1.994 ± 0.932
0.499MetMet: 0.499 ± 0.513
1.994MetAsn: 1.994 ± 0.821
0.997MetPro: 0.997 ± 0.543
1.496MetGln: 1.496 ± 0.921
0.997MetArg: 0.997 ± 0.677
1.994MetSer: 1.994 ± 0.892
2.493MetThr: 2.493 ± 1.162
0.997MetVal: 0.997 ± 0.586
0.0MetTrp: 0.0 ± 0.0
0.499MetTyr: 0.499 ± 0.512
0.0MetXaa: 0.0 ± 0.0
Asn
1.994AsnAla: 1.994 ± 1.006
0.0AsnCys: 0.0 ± 0.0
2.493AsnAsp: 2.493 ± 1.266
3.49AsnGlu: 3.49 ± 1.177
2.493AsnPhe: 2.493 ± 1.129
2.991AsnGly: 2.991 ± 0.899
0.0AsnHis: 0.0 ± 0.0
4.985AsnIle: 4.985 ± 1.096
6.481AsnLys: 6.481 ± 1.788
3.988AsnLeu: 3.988 ± 1.464
1.496AsnMet: 1.496 ± 0.9
3.988AsnAsn: 3.988 ± 1.322
1.994AsnPro: 1.994 ± 1.011
2.991AsnGln: 2.991 ± 1.348
1.994AsnArg: 1.994 ± 1.008
2.991AsnSer: 2.991 ± 1.016
2.493AsnThr: 2.493 ± 1.282
1.496AsnVal: 1.496 ± 0.969
1.496AsnTrp: 1.496 ± 0.849
2.493AsnTyr: 2.493 ± 1.207
0.0AsnXaa: 0.0 ± 0.0
Pro
0.997ProAla: 0.997 ± 0.689
0.499ProCys: 0.499 ± 0.413
0.997ProAsp: 0.997 ± 0.545
2.493ProGlu: 2.493 ± 0.972
2.493ProPhe: 2.493 ± 1.048
0.0ProGly: 0.0 ± 0.0
0.499ProHis: 0.499 ± 0.473
1.496ProIle: 1.496 ± 0.699
4.487ProLys: 4.487 ± 1.15
0.997ProLeu: 0.997 ± 0.718
0.499ProMet: 0.499 ± 0.466
0.499ProAsn: 0.499 ± 0.459
0.997ProPro: 0.997 ± 0.604
1.496ProGln: 1.496 ± 0.723
2.493ProArg: 2.493 ± 1.073
0.499ProSer: 0.499 ± 0.466
1.496ProThr: 1.496 ± 0.883
0.499ProVal: 0.499 ± 0.517
0.0ProTrp: 0.0 ± 0.0
0.499ProTyr: 0.499 ± 0.459
0.0ProXaa: 0.0 ± 0.0
Gln
2.991GlnAla: 2.991 ± 0.918
0.499GlnCys: 0.499 ± 0.513
2.493GlnAsp: 2.493 ± 1.469
3.988GlnGlu: 3.988 ± 0.933
0.997GlnPhe: 0.997 ± 0.677
1.994GlnGly: 1.994 ± 1.005
0.0GlnHis: 0.0 ± 0.0
3.988GlnIle: 3.988 ± 1.119
2.991GlnLys: 2.991 ± 1.283
7.478GlnLeu: 7.478 ± 2.183
1.496GlnMet: 1.496 ± 0.655
1.496GlnAsn: 1.496 ± 0.675
0.0GlnPro: 0.0 ± 0.0
3.49GlnGln: 3.49 ± 1.104
0.997GlnArg: 0.997 ± 0.755
3.988GlnSer: 3.988 ± 1.475
0.997GlnThr: 0.997 ± 0.64
1.994GlnVal: 1.994 ± 0.708
0.0GlnTrp: 0.0 ± 0.0
3.49GlnTyr: 3.49 ± 1.286
0.0GlnXaa: 0.0 ± 0.0
Arg
0.997ArgAla: 0.997 ± 0.713
0.499ArgCys: 0.499 ± 0.466
2.991ArgAsp: 2.991 ± 1.351
4.985ArgGlu: 4.985 ± 1.543
0.997ArgPhe: 0.997 ± 0.547
3.49ArgGly: 3.49 ± 1.062
0.997ArgHis: 0.997 ± 0.694
2.493ArgIle: 2.493 ± 1.039
3.988ArgLys: 3.988 ± 1.442
8.475ArgLeu: 8.475 ± 1.939
0.0ArgMet: 0.0 ± 0.0
1.496ArgAsn: 1.496 ± 0.641
1.496ArgPro: 1.496 ± 0.67
3.49ArgGln: 3.49 ± 1.138
2.493ArgArg: 2.493 ± 0.983
1.994ArgSer: 1.994 ± 1.107
4.487ArgThr: 4.487 ± 1.848
5.982ArgVal: 5.982 ± 1.192
0.997ArgTrp: 0.997 ± 0.578
2.493ArgTyr: 2.493 ± 1.177
0.0ArgXaa: 0.0 ± 0.0
Ser
1.994SerAla: 1.994 ± 1.259
0.499SerCys: 0.499 ± 0.473
3.49SerAsp: 3.49 ± 1.14
3.988SerGlu: 3.988 ± 1.42
3.49SerPhe: 3.49 ± 1.479
2.493SerGly: 2.493 ± 0.995
0.499SerHis: 0.499 ± 0.473
7.478SerIle: 7.478 ± 1.417
2.991SerLys: 2.991 ± 1.374
5.982SerLeu: 5.982 ± 1.117
0.499SerMet: 0.499 ± 0.596
1.994SerAsn: 1.994 ± 0.906
0.0SerPro: 0.0 ± 0.0
3.49SerGln: 3.49 ± 0.878
1.496SerArg: 1.496 ± 0.702
1.496SerSer: 1.496 ± 0.992
3.988SerThr: 3.988 ± 1.133
3.988SerVal: 3.988 ± 1.509
0.0SerTrp: 0.0 ± 0.0
3.49SerTyr: 3.49 ± 1.169
0.0SerXaa: 0.0 ± 0.0
Thr
0.997ThrAla: 0.997 ± 0.665
0.0ThrCys: 0.0 ± 0.0
3.49ThrAsp: 3.49 ± 1.266
2.991ThrGlu: 2.991 ± 0.895
3.49ThrPhe: 3.49 ± 1.078
3.49ThrGly: 3.49 ± 1.195
1.496ThrHis: 1.496 ± 0.692
5.982ThrIle: 5.982 ± 1.324
4.985ThrLys: 4.985 ± 1.427
7.976ThrLeu: 7.976 ± 1.534
0.499ThrMet: 0.499 ± 0.445
1.994ThrAsn: 1.994 ± 0.858
2.493ThrPro: 2.493 ± 0.892
2.991ThrGln: 2.991 ± 1.287
3.988ThrArg: 3.988 ± 1.358
1.496ThrSer: 1.496 ± 0.873
1.994ThrThr: 1.994 ± 0.857
3.988ThrVal: 3.988 ± 1.258
0.499ThrTrp: 0.499 ± 0.498
1.496ThrTyr: 1.496 ± 0.781
0.0ThrXaa: 0.0 ± 0.0
Val
2.991ValAla: 2.991 ± 1.031
0.499ValCys: 0.499 ± 0.413
3.49ValAsp: 3.49 ± 1.0
1.496ValGlu: 1.496 ± 0.9
1.994ValPhe: 1.994 ± 0.922
2.493ValGly: 2.493 ± 1.067
1.496ValHis: 1.496 ± 0.768
2.991ValIle: 2.991 ± 1.369
3.988ValLys: 3.988 ± 1.323
3.49ValLeu: 3.49 ± 1.183
0.499ValMet: 0.499 ± 0.588
3.49ValAsn: 3.49 ± 1.604
0.499ValPro: 0.499 ± 0.413
2.991ValGln: 2.991 ± 0.965
2.991ValArg: 2.991 ± 1.093
5.982ValSer: 5.982 ± 1.411
4.487ValThr: 4.487 ± 1.565
1.994ValVal: 1.994 ± 0.88
0.0ValTrp: 0.0 ± 0.0
1.496ValTyr: 1.496 ± 0.862
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.997TrpAsp: 0.997 ± 0.601
2.493TrpGlu: 2.493 ± 1.22
0.0TrpPhe: 0.0 ± 0.0
0.997TrpGly: 0.997 ± 0.545
0.499TrpHis: 0.499 ± 0.413
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.997TrpLeu: 0.997 ± 0.617
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.499TrpGln: 0.499 ± 0.413
0.499TrpArg: 0.499 ± 0.556
0.997TrpSer: 0.997 ± 0.598
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.997TrpTyr: 0.997 ± 0.967
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.997TyrAla: 0.997 ± 0.804
0.499TyrCys: 0.499 ± 0.518
0.499TyrAsp: 0.499 ± 0.588
2.991TyrGlu: 2.991 ± 0.915
2.493TyrPhe: 2.493 ± 1.287
0.997TyrGly: 0.997 ± 0.677
0.499TyrHis: 0.499 ± 0.505
2.991TyrIle: 2.991 ± 0.922
7.478TyrLys: 7.478 ± 1.799
3.988TyrLeu: 3.988 ± 1.253
1.994TyrMet: 1.994 ± 1.864
2.991TyrAsn: 2.991 ± 0.91
0.499TyrPro: 0.499 ± 0.513
3.49TyrGln: 3.49 ± 0.883
4.487TyrArg: 4.487 ± 1.437
4.985TyrSer: 4.985 ± 1.195
2.493TyrThr: 2.493 ± 1.266
1.994TyrVal: 1.994 ± 0.923
0.997TyrTrp: 0.997 ± 0.601
2.991TyrTyr: 2.991 ± 1.435
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 19 proteins (2007 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski