Amino acid dipepetide frequency for Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.723AlaAla: 9.723 ± 0.105
1.027AlaCys: 1.027 ± 0.031
4.983AlaAsp: 4.983 ± 0.068
5.675AlaGlu: 5.675 ± 0.067
3.493AlaPhe: 3.493 ± 0.05
7.237AlaGly: 7.237 ± 0.099
1.797AlaHis: 1.797 ± 0.035
5.96AlaIle: 5.96 ± 0.068
3.648AlaLys: 3.648 ± 0.064
11.713AlaLeu: 11.713 ± 0.118
2.711AlaMet: 2.711 ± 0.052
3.188AlaAsn: 3.188 ± 0.063
3.483AlaPro: 3.483 ± 0.056
4.557AlaGln: 4.557 ± 0.068
5.018AlaArg: 5.018 ± 0.077
5.808AlaSer: 5.808 ± 0.08
4.887AlaThr: 4.887 ± 0.07
6.637AlaVal: 6.637 ± 0.08
1.208AlaTrp: 1.208 ± 0.027
2.377AlaTyr: 2.377 ± 0.047
0.0AlaXaa: 0.0 ± 0.0
Cys
0.909CysAla: 0.909 ± 0.026
0.18CysCys: 0.18 ± 0.011
0.548CysAsp: 0.548 ± 0.021
0.546CysGlu: 0.546 ± 0.023
0.396CysPhe: 0.396 ± 0.017
0.984CysGly: 0.984 ± 0.029
0.305CysHis: 0.305 ± 0.017
0.558CysIle: 0.558 ± 0.022
0.308CysLys: 0.308 ± 0.016
0.994CysLeu: 0.994 ± 0.026
0.225CysMet: 0.225 ± 0.013
0.315CysAsn: 0.315 ± 0.015
0.495CysPro: 0.495 ± 0.023
0.47CysGln: 0.47 ± 0.017
0.607CysArg: 0.607 ± 0.021
0.65CysSer: 0.65 ± 0.023
0.485CysThr: 0.485 ± 0.022
0.723CysVal: 0.723 ± 0.025
0.181CysTrp: 0.181 ± 0.01
0.338CysTyr: 0.338 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
5.256AspAla: 5.256 ± 0.084
0.486AspCys: 0.486 ± 0.019
3.122AspAsp: 3.122 ± 0.054
3.537AspGlu: 3.537 ± 0.057
2.076AspPhe: 2.076 ± 0.04
3.875AspGly: 3.875 ± 0.073
0.99AspHis: 0.99 ± 0.027
3.757AspIle: 3.757 ± 0.053
2.406AspLys: 2.406 ± 0.046
4.658AspLeu: 4.658 ± 0.069
1.335AspMet: 1.335 ± 0.032
2.261AspAsn: 2.261 ± 0.065
2.186AspPro: 2.186 ± 0.04
1.579AspGln: 1.579 ± 0.032
2.854AspArg: 2.854 ± 0.045
3.131AspSer: 3.131 ± 0.051
2.756AspThr: 2.756 ± 0.06
4.033AspVal: 4.033 ± 0.062
0.851AspTrp: 0.851 ± 0.027
1.907AspTyr: 1.907 ± 0.043
0.0AspXaa: 0.0 ± 0.0
Glu
4.921GluAla: 4.921 ± 0.061
0.453GluCys: 0.453 ± 0.02
2.317GluAsp: 2.317 ± 0.043
3.137GluGlu: 3.137 ± 0.06
1.822GluPhe: 1.822 ± 0.034
3.376GluGly: 3.376 ± 0.058
1.467GluHis: 1.467 ± 0.034
3.334GluIle: 3.334 ± 0.058
3.233GluLys: 3.233 ± 0.057
6.031GluLeu: 6.031 ± 0.076
1.629GluMet: 1.629 ± 0.03
2.336GluAsn: 2.336 ± 0.045
2.129GluPro: 2.129 ± 0.046
3.614GluGln: 3.614 ± 0.062
3.825GluArg: 3.825 ± 0.061
3.136GluSer: 3.136 ± 0.05
2.929GluThr: 2.929 ± 0.046
3.468GluVal: 3.468 ± 0.07
0.775GluTrp: 0.775 ± 0.024
1.416GluTyr: 1.416 ± 0.034
0.0GluXaa: 0.0 ± 0.0
Phe
3.385PheAla: 3.385 ± 0.057
0.503PheCys: 0.503 ± 0.019
2.317PheAsp: 2.317 ± 0.042
1.65PheGlu: 1.65 ± 0.037
1.665PhePhe: 1.665 ± 0.041
3.051PheGly: 3.051 ± 0.057
0.855PheHis: 0.855 ± 0.024
2.556PheIle: 2.556 ± 0.051
1.276PheLys: 1.276 ± 0.032
3.422PheLeu: 3.422 ± 0.057
0.936PheMet: 0.936 ± 0.03
1.699PheAsn: 1.699 ± 0.039
1.555PhePro: 1.555 ± 0.032
1.218PheGln: 1.218 ± 0.031
1.86PheArg: 1.86 ± 0.041
3.342PheSer: 3.342 ± 0.053
2.292PheThr: 2.292 ± 0.046
2.399PheVal: 2.399 ± 0.044
0.58PheTrp: 0.58 ± 0.021
1.27PheTyr: 1.27 ± 0.034
0.0PheXaa: 0.0 ± 0.0
Gly
5.82GlyAla: 5.82 ± 0.071
0.953GlyCys: 0.953 ± 0.031
3.608GlyAsp: 3.608 ± 0.067
4.347GlyGlu: 4.347 ± 0.068
3.15GlyPhe: 3.15 ± 0.052
5.158GlyGly: 5.158 ± 0.079
1.594GlyHis: 1.594 ± 0.035
4.923GlyIle: 4.923 ± 0.067
3.974GlyLys: 3.974 ± 0.061
7.285GlyLeu: 7.285 ± 0.077
2.246GlyMet: 2.246 ± 0.042
2.897GlyAsn: 2.897 ± 0.066
1.872GlyPro: 1.872 ± 0.04
3.031GlyGln: 3.031 ± 0.049
3.683GlyArg: 3.683 ± 0.055
4.356GlySer: 4.356 ± 0.073
3.78GlyThr: 3.78 ± 0.067
5.555GlyVal: 5.555 ± 0.067
1.226GlyTrp: 1.226 ± 0.03
2.608GlyTyr: 2.608 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
2.031HisAla: 2.031 ± 0.038
0.315HisCys: 0.315 ± 0.014
1.281HisAsp: 1.281 ± 0.037
1.121HisGlu: 1.121 ± 0.03
1.017HisPhe: 1.017 ± 0.023
1.64HisGly: 1.64 ± 0.036
0.801HisHis: 0.801 ± 0.029
1.357HisIle: 1.357 ± 0.033
0.738HisLys: 0.738 ± 0.023
2.338HisLeu: 2.338 ± 0.052
0.496HisMet: 0.496 ± 0.018
0.826HisAsn: 0.826 ± 0.027
1.312HisPro: 1.312 ± 0.035
1.272HisGln: 1.272 ± 0.032
1.321HisArg: 1.321 ± 0.033
1.373HisSer: 1.373 ± 0.033
1.096HisThr: 1.096 ± 0.027
1.313HisVal: 1.313 ± 0.036
0.4HisTrp: 0.4 ± 0.018
0.873HisTyr: 0.873 ± 0.026
0.0HisXaa: 0.0 ± 0.0
Ile
6.532IleAla: 6.532 ± 0.082
0.634IleCys: 0.634 ± 0.021
3.695IleAsp: 3.695 ± 0.058
3.543IleGlu: 3.543 ± 0.053
2.006IlePhe: 2.006 ± 0.041
4.837IleGly: 4.837 ± 0.062
1.219IleHis: 1.219 ± 0.03
3.351IleIle: 3.351 ± 0.064
2.475IleLys: 2.475 ± 0.045
5.137IleLeu: 5.137 ± 0.072
1.3IleMet: 1.3 ± 0.033
2.678IleAsn: 2.678 ± 0.043
2.761IlePro: 2.761 ± 0.041
2.053IleGln: 2.053 ± 0.039
3.105IleArg: 3.105 ± 0.05
4.134IleSer: 4.134 ± 0.064
3.741IleThr: 3.741 ± 0.059
4.13IleVal: 4.13 ± 0.066
0.667IleTrp: 0.667 ± 0.02
1.594IleTyr: 1.594 ± 0.035
0.0IleXaa: 0.0 ± 0.0
Lys
3.983LysAla: 3.983 ± 0.056
0.239LysCys: 0.239 ± 0.015
2.086LysAsp: 2.086 ± 0.046
2.325LysGlu: 2.325 ± 0.048
1.052LysPhe: 1.052 ± 0.029
2.808LysGly: 2.808 ± 0.053
0.915LysHis: 0.915 ± 0.027
2.473LysIle: 2.473 ± 0.052
2.244LysLys: 2.244 ± 0.05
4.191LysLeu: 4.191 ± 0.054
1.169LysMet: 1.169 ± 0.029
1.839LysAsn: 1.839 ± 0.042
2.079LysPro: 2.079 ± 0.048
2.116LysGln: 2.116 ± 0.044
2.501LysArg: 2.501 ± 0.054
2.415LysSer: 2.415 ± 0.051
2.635LysThr: 2.635 ± 0.05
2.806LysVal: 2.806 ± 0.054
0.411LysTrp: 0.411 ± 0.017
1.049LysTyr: 1.049 ± 0.037
0.0LysXaa: 0.0 ± 0.0
Leu
11.373LeuAla: 11.373 ± 0.101
1.267LeuCys: 1.267 ± 0.032
5.716LeuAsp: 5.716 ± 0.08
5.267LeuGlu: 5.267 ± 0.068
4.255LeuPhe: 4.255 ± 0.071
7.262LeuGly: 7.262 ± 0.089
2.351LeuHis: 2.351 ± 0.043
6.139LeuIle: 6.139 ± 0.079
4.366LeuLys: 4.366 ± 0.058
12.437LeuLeu: 12.437 ± 0.138
2.812LeuMet: 2.812 ± 0.049
4.403LeuAsn: 4.403 ± 0.071
5.801LeuPro: 5.801 ± 0.078
4.365LeuGln: 4.365 ± 0.064
6.062LeuArg: 6.062 ± 0.085
8.088LeuSer: 8.088 ± 0.091
6.598LeuThr: 6.598 ± 0.088
7.044LeuVal: 7.044 ± 0.077
1.293LeuTrp: 1.293 ± 0.033
2.647LeuTyr: 2.647 ± 0.047
0.0LeuXaa: 0.0 ± 0.0
Met
2.61MetAla: 2.61 ± 0.043
0.164MetCys: 0.164 ± 0.01
1.156MetAsp: 1.156 ± 0.027
1.192MetGlu: 1.192 ± 0.03
0.842MetPhe: 0.842 ± 0.03
1.746MetGly: 1.746 ± 0.041
0.482MetHis: 0.482 ± 0.016
1.418MetIle: 1.418 ± 0.035
1.353MetLys: 1.353 ± 0.03
3.135MetLeu: 3.135 ± 0.052
0.871MetMet: 0.871 ± 0.03
1.065MetAsn: 1.065 ± 0.023
1.258MetPro: 1.258 ± 0.033
1.213MetGln: 1.213 ± 0.031
1.386MetArg: 1.386 ± 0.03
1.875MetSer: 1.875 ± 0.041
1.766MetThr: 1.766 ± 0.039
1.849MetVal: 1.849 ± 0.042
0.211MetTrp: 0.211 ± 0.011
0.479MetTyr: 0.479 ± 0.019
0.0MetXaa: 0.0 ± 0.0
Asn
3.666AsnAla: 3.666 ± 0.06
0.323AsnCys: 0.323 ± 0.018
2.141AsnAsp: 2.141 ± 0.038
1.976AsnGlu: 1.976 ± 0.036
1.26AsnPhe: 1.26 ± 0.033
3.032AsnGly: 3.032 ± 0.059
0.881AsnHis: 0.881 ± 0.027
2.461AsnIle: 2.461 ± 0.046
1.597AsnLys: 1.597 ± 0.042
3.507AsnLeu: 3.507 ± 0.055
0.903AsnMet: 0.903 ± 0.023
1.633AsnAsn: 1.633 ± 0.043
2.055AsnPro: 2.055 ± 0.043
1.732AsnGln: 1.732 ± 0.039
2.105AsnArg: 2.105 ± 0.045
2.195AsnSer: 2.195 ± 0.044
2.237AsnThr: 2.237 ± 0.048
2.755AsnVal: 2.755 ± 0.095
0.557AsnTrp: 0.557 ± 0.018
1.167AsnTyr: 1.167 ± 0.034
0.0AsnXaa: 0.0 ± 0.0
Pro
4.354ProAla: 4.354 ± 0.068
0.364ProCys: 0.364 ± 0.016
2.883ProAsp: 2.883 ± 0.058
3.213ProGlu: 3.213 ± 0.052
1.812ProPhe: 1.812 ± 0.042
2.923ProGly: 2.923 ± 0.048
1.104ProHis: 1.104 ± 0.028
2.204ProIle: 2.204 ± 0.048
1.501ProLys: 1.501 ± 0.033
5.144ProLeu: 5.144 ± 0.08
1.076ProMet: 1.076 ± 0.028
1.425ProAsn: 1.425 ± 0.033
1.659ProPro: 1.659 ± 0.035
2.173ProGln: 2.173 ± 0.044
1.912ProArg: 1.912 ± 0.035
2.531ProSer: 2.531 ± 0.044
2.372ProThr: 2.372 ± 0.049
3.521ProVal: 3.521 ± 0.052
0.641ProTrp: 0.641 ± 0.02
1.31ProTyr: 1.31 ± 0.031
0.0ProXaa: 0.0 ± 0.0
Gln
4.821GlnAla: 4.821 ± 0.074
0.397GlnCys: 0.397 ± 0.016
2.118GlnAsp: 2.118 ± 0.04
2.313GlnGlu: 2.313 ± 0.043
1.491GlnPhe: 1.491 ± 0.032
3.221GlnGly: 3.221 ± 0.054
1.363GlnHis: 1.363 ± 0.032
2.367GlnIle: 2.367 ± 0.04
1.831GlnLys: 1.831 ± 0.037
5.215GlnLeu: 5.215 ± 0.07
1.113GlnMet: 1.113 ± 0.028
1.48GlnAsn: 1.48 ± 0.034
2.358GlnPro: 2.358 ± 0.047
3.682GlnGln: 3.682 ± 0.078
3.45GlnArg: 3.45 ± 0.053
2.593GlnSer: 2.593 ± 0.042
2.418GlnThr: 2.418 ± 0.064
3.113GlnVal: 3.113 ± 0.052
0.659GlnTrp: 0.659 ± 0.023
1.145GlnTyr: 1.145 ± 0.029
0.0GlnXaa: 0.0 ± 0.0
Arg
4.408ArgAla: 4.408 ± 0.06
0.586ArgCys: 0.586 ± 0.019
3.027ArgAsp: 3.027 ± 0.046
3.515ArgGlu: 3.515 ± 0.057
2.569ArgPhe: 2.569 ± 0.042
3.307ArgGly: 3.307 ± 0.053
1.618ArgHis: 1.618 ± 0.039
3.499ArgIle: 3.499 ± 0.049
2.262ArgLys: 2.262 ± 0.039
6.553ArgLeu: 6.553 ± 0.085
1.465ArgMet: 1.465 ± 0.034
2.011ArgAsn: 2.011 ± 0.034
2.121ArgPro: 2.121 ± 0.04
3.301ArgGln: 3.301 ± 0.063
3.406ArgArg: 3.406 ± 0.061
3.011ArgSer: 3.011 ± 0.052
2.641ArgThr: 2.641 ± 0.044
3.786ArgVal: 3.786 ± 0.051
0.99ArgTrp: 0.99 ± 0.027
2.236ArgTyr: 2.236 ± 0.052
0.0ArgXaa: 0.0 ± 0.0
Ser
6.169SerAla: 6.169 ± 0.079
0.61SerCys: 0.61 ± 0.023
3.383SerAsp: 3.383 ± 0.064
3.412SerGlu: 3.412 ± 0.05
2.358SerPhe: 2.358 ± 0.045
5.642SerGly: 5.642 ± 0.08
1.479SerHis: 1.479 ± 0.034
3.458SerIle: 3.458 ± 0.06
2.08SerLys: 2.08 ± 0.043
7.374SerLeu: 7.374 ± 0.089
1.563SerMet: 1.563 ± 0.034
2.139SerAsn: 2.139 ± 0.046
2.796SerPro: 2.796 ± 0.048
2.862SerGln: 2.862 ± 0.055
3.479SerArg: 3.479 ± 0.049
4.187SerSer: 4.187 ± 0.065
3.362SerThr: 3.362 ± 0.057
4.598SerVal: 4.598 ± 0.06
0.954SerTrp: 0.954 ± 0.027
1.721SerTyr: 1.721 ± 0.035
0.0SerXaa: 0.0 ± 0.0
Thr
5.106ThrAla: 5.106 ± 0.082
0.442ThrCys: 0.442 ± 0.016
2.747ThrAsp: 2.747 ± 0.046
2.869ThrGlu: 2.869 ± 0.046
2.085ThrPhe: 2.085 ± 0.041
4.191ThrGly: 4.191 ± 0.058
1.262ThrHis: 1.262 ± 0.032
3.082ThrIle: 3.082 ± 0.063
1.597ThrLys: 1.597 ± 0.039
7.653ThrLeu: 7.653 ± 0.106
1.156ThrMet: 1.156 ± 0.028
1.751ThrAsn: 1.751 ± 0.041
3.264ThrPro: 3.264 ± 0.055
2.496ThrGln: 2.496 ± 0.045
3.032ThrArg: 3.032 ± 0.046
3.245ThrSer: 3.245 ± 0.053
3.178ThrThr: 3.178 ± 0.087
4.121ThrVal: 4.121 ± 0.113
0.68ThrTrp: 0.68 ± 0.029
1.415ThrTyr: 1.415 ± 0.042
0.0ThrXaa: 0.0 ± 0.0
Val
6.709ValAla: 6.709 ± 0.075
0.745ValCys: 0.745 ± 0.023
3.746ValAsp: 3.746 ± 0.069
3.893ValGlu: 3.893 ± 0.058
2.651ValPhe: 2.651 ± 0.053
4.791ValGly: 4.791 ± 0.069
1.231ValHis: 1.231 ± 0.029
4.584ValIle: 4.584 ± 0.063
3.057ValLys: 3.057 ± 0.055
7.38ValLeu: 7.38 ± 0.069
2.108ValMet: 2.108 ± 0.043
2.794ValAsn: 2.794 ± 0.063
2.896ValPro: 2.896 ± 0.049
2.498ValGln: 2.498 ± 0.049
3.644ValArg: 3.644 ± 0.054
4.851ValSer: 4.851 ± 0.052
4.242ValThr: 4.242 ± 0.126
5.262ValVal: 5.262 ± 0.073
0.879ValTrp: 0.879 ± 0.024
1.728ValTyr: 1.728 ± 0.034
0.0ValXaa: 0.0 ± 0.0
Trp
0.948TrpAla: 0.948 ± 0.027
0.158TrpCys: 0.158 ± 0.011
0.589TrpAsp: 0.589 ± 0.02
0.588TrpGlu: 0.588 ± 0.019
0.603TrpPhe: 0.603 ± 0.024
0.836TrpGly: 0.836 ± 0.027
0.414TrpHis: 0.414 ± 0.019
0.675TrpIle: 0.675 ± 0.025
0.48TrpLys: 0.48 ± 0.018
2.123TrpLeu: 2.123 ± 0.049
0.36TrpMet: 0.36 ± 0.015
0.467TrpAsn: 0.467 ± 0.02
0.577TrpPro: 0.577 ± 0.023
1.158TrpGln: 1.158 ± 0.031
1.011TrpArg: 1.011 ± 0.028
0.86TrpSer: 0.86 ± 0.036
0.521TrpThr: 0.521 ± 0.019
0.899TrpVal: 0.899 ± 0.031
0.223TrpTrp: 0.223 ± 0.012
0.369TrpTyr: 0.369 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.405TyrAla: 2.405 ± 0.045
0.372TyrCys: 0.372 ± 0.017
1.594TyrAsp: 1.594 ± 0.047
1.227TyrGlu: 1.227 ± 0.033
1.228TyrPhe: 1.228 ± 0.032
2.149TyrGly: 2.149 ± 0.045
0.792TyrHis: 0.792 ± 0.026
1.435TyrIle: 1.435 ± 0.034
0.911TyrLys: 0.911 ± 0.029
3.258TyrLeu: 3.258 ± 0.057
0.595TyrMet: 0.595 ± 0.022
0.976TyrAsn: 0.976 ± 0.032
1.468TyrPro: 1.468 ± 0.034
1.755TyrGln: 1.755 ± 0.034
2.051TyrArg: 2.051 ± 0.037
1.844TyrSer: 1.844 ± 0.04
1.435TyrThr: 1.435 ± 0.038
1.68TyrVal: 1.68 ± 0.038
0.473TyrTrp: 0.473 ± 0.019
0.928TyrTyr: 0.928 ± 0.028
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4459 proteins (1442513 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski