Amino acid dipepetide frequency for Leptonychotes weddellii papillomavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.355AlaAla: 4.355 ± 1.059
1.742AlaCys: 1.742 ± 0.774
2.613AlaAsp: 2.613 ± 0.971
2.613AlaGlu: 2.613 ± 0.886
2.178AlaPhe: 2.178 ± 0.787
2.178AlaGly: 2.178 ± 1.842
0.871AlaHis: 0.871 ± 0.752
2.613AlaIle: 2.613 ± 1.309
2.613AlaLys: 2.613 ± 0.984
5.226AlaLeu: 5.226 ± 1.246
1.307AlaMet: 1.307 ± 0.636
1.742AlaAsn: 1.742 ± 0.656
4.355AlaPro: 4.355 ± 1.003
1.742AlaGln: 1.742 ± 1.001
2.613AlaArg: 2.613 ± 0.657
5.226AlaSer: 5.226 ± 1.492
3.484AlaThr: 3.484 ± 0.7
4.355AlaVal: 4.355 ± 1.68
0.436AlaTrp: 0.436 ± 0.355
2.613AlaTyr: 2.613 ± 0.492
0.0AlaXaa: 0.0 ± 0.0
Cys
1.742CysAla: 1.742 ± 1.282
0.0CysCys: 0.0 ± 0.0
1.742CysAsp: 1.742 ± 0.956
1.307CysGlu: 1.307 ± 0.935
0.871CysPhe: 0.871 ± 0.71
2.178CysGly: 2.178 ± 1.598
0.436CysHis: 0.436 ± 0.376
0.871CysIle: 0.871 ± 0.71
2.613CysLys: 2.613 ± 1.273
0.871CysLeu: 0.871 ± 0.685
0.871CysMet: 0.871 ± 0.715
0.436CysAsn: 0.436 ± 0.355
1.307CysPro: 1.307 ± 0.725
0.436CysGln: 0.436 ± 0.355
0.871CysArg: 0.871 ± 0.715
2.178CysSer: 2.178 ± 1.354
0.871CysThr: 0.871 ± 0.685
1.307CysVal: 1.307 ± 1.142
1.307CysTrp: 1.307 ± 0.655
0.436CysTyr: 0.436 ± 0.355
0.0CysXaa: 0.0 ± 0.0
Asp
3.484AspAla: 3.484 ± 0.552
2.178AspCys: 2.178 ± 0.821
3.049AspAsp: 3.049 ± 0.688
4.355AspGlu: 4.355 ± 0.869
2.178AspPhe: 2.178 ± 0.979
3.049AspGly: 3.049 ± 1.359
0.436AspHis: 0.436 ± 0.379
4.791AspIle: 4.791 ± 1.472
2.178AspLys: 2.178 ± 1.325
5.662AspLeu: 5.662 ± 1.435
0.0AspMet: 0.0 ± 0.0
3.049AspAsn: 3.049 ± 1.258
4.355AspPro: 4.355 ± 1.294
1.307AspGln: 1.307 ± 0.79
2.613AspArg: 2.613 ± 1.574
3.484AspSer: 3.484 ± 1.144
4.791AspThr: 4.791 ± 0.908
3.484AspVal: 3.484 ± 1.084
1.742AspTrp: 1.742 ± 0.991
2.178AspTyr: 2.178 ± 0.903
0.0AspXaa: 0.0 ± 0.0
Glu
2.613GluAla: 2.613 ± 0.489
1.742GluCys: 1.742 ± 1.42
4.355GluAsp: 4.355 ± 0.686
9.582GluGlu: 9.582 ± 3.498
2.613GluPhe: 2.613 ± 1.258
3.049GluGly: 3.049 ± 2.105
0.871GluHis: 0.871 ± 0.461
3.049GluIle: 3.049 ± 1.326
2.613GluLys: 2.613 ± 1.036
7.404GluLeu: 7.404 ± 0.9
1.307GluMet: 1.307 ± 0.672
4.791GluAsn: 4.791 ± 1.084
5.226GluPro: 5.226 ± 1.648
2.613GluGln: 2.613 ± 1.31
2.613GluArg: 2.613 ± 0.947
3.92GluSer: 3.92 ± 1.346
3.049GluThr: 3.049 ± 1.435
3.049GluVal: 3.049 ± 1.319
0.436GluTrp: 0.436 ± 0.376
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.613PheAla: 2.613 ± 1.057
1.307PheCys: 1.307 ± 0.655
2.613PheAsp: 2.613 ± 1.307
3.049PheGlu: 3.049 ± 0.71
1.307PhePhe: 1.307 ± 0.79
2.613PheGly: 2.613 ± 0.489
0.871PheHis: 0.871 ± 0.492
2.613PheIle: 2.613 ± 0.841
2.178PheLys: 2.178 ± 0.732
3.92PheLeu: 3.92 ± 1.744
0.0PheMet: 0.0 ± 0.0
1.307PheAsn: 1.307 ± 0.636
1.742PhePro: 1.742 ± 0.277
0.436PheGln: 0.436 ± 0.376
1.742PheArg: 1.742 ± 1.135
2.178PheSer: 2.178 ± 0.671
2.178PheThr: 2.178 ± 0.902
2.178PheVal: 2.178 ± 0.9
1.742PheTrp: 1.742 ± 0.628
2.178PheTyr: 2.178 ± 0.829
0.0PheXaa: 0.0 ± 0.0
Gly
3.92GlyAla: 3.92 ± 1.471
1.307GlyCys: 1.307 ± 0.79
4.791GlyAsp: 4.791 ± 1.874
6.969GlyGlu: 6.969 ± 0.888
2.613GlyPhe: 2.613 ± 1.157
8.275GlyGly: 8.275 ± 3.301
0.871GlyHis: 0.871 ± 0.752
3.484GlyIle: 3.484 ± 1.135
3.484GlyLys: 3.484 ± 1.277
6.533GlyLeu: 6.533 ± 1.202
0.871GlyMet: 0.871 ± 0.752
4.791GlyAsn: 4.791 ± 1.744
3.484GlyPro: 3.484 ± 1.084
2.613GlyGln: 2.613 ± 1.422
6.533GlyArg: 6.533 ± 2.012
5.226GlySer: 5.226 ± 1.585
4.791GlyThr: 4.791 ± 1.322
1.742GlyVal: 1.742 ± 0.51
0.0GlyTrp: 0.0 ± 0.0
1.307GlyTyr: 1.307 ± 0.675
0.0GlyXaa: 0.0 ± 0.0
His
1.742HisAla: 1.742 ± 0.738
0.436HisCys: 0.436 ± 0.355
0.0HisAsp: 0.0 ± 0.0
0.436HisGlu: 0.436 ± 0.664
1.742HisPhe: 1.742 ± 0.991
1.307HisGly: 1.307 ± 0.698
0.0HisHis: 0.0 ± 0.0
1.307HisIle: 1.307 ± 0.713
0.436HisLys: 0.436 ± 0.355
0.871HisLeu: 0.871 ± 0.435
0.0HisMet: 0.0 ± 0.0
0.436HisAsn: 0.436 ± 0.355
1.742HisPro: 1.742 ± 0.87
0.436HisGln: 0.436 ± 0.355
1.307HisArg: 1.307 ± 0.795
1.742HisSer: 1.742 ± 0.674
1.307HisThr: 1.307 ± 0.725
0.436HisVal: 0.436 ± 0.355
0.436HisTrp: 0.436 ± 0.376
1.307HisTyr: 1.307 ± 0.439
0.0HisXaa: 0.0 ± 0.0
Ile
3.049IleAla: 3.049 ± 0.958
0.436IleCys: 0.436 ± 0.376
3.484IleAsp: 3.484 ± 1.021
1.742IleGlu: 1.742 ± 1.029
1.307IlePhe: 1.307 ± 0.725
3.92IleGly: 3.92 ± 1.209
0.436IleHis: 0.436 ± 0.355
0.436IleIle: 0.436 ± 0.368
0.871IleLys: 0.871 ± 0.71
4.791IleLeu: 4.791 ± 0.985
0.871IleMet: 0.871 ± 0.492
1.307IleAsn: 1.307 ± 0.781
3.484IlePro: 3.484 ± 1.239
0.871IleGln: 0.871 ± 0.435
2.613IleArg: 2.613 ± 0.965
5.226IleSer: 5.226 ± 1.203
2.613IleThr: 2.613 ± 1.057
2.613IleVal: 2.613 ± 0.886
0.0IleTrp: 0.0 ± 0.0
0.871IleTyr: 0.871 ± 0.435
0.0IleXaa: 0.0 ± 0.0
Lys
2.613LysAla: 2.613 ± 0.659
0.436LysCys: 0.436 ± 0.376
2.178LysAsp: 2.178 ± 1.054
1.742LysGlu: 1.742 ± 0.956
3.049LysPhe: 3.049 ± 1.024
2.613LysGly: 2.613 ± 1.113
2.178LysHis: 2.178 ± 0.732
0.871LysIle: 0.871 ± 0.71
6.098LysLys: 6.098 ± 1.04
2.613LysLeu: 2.613 ± 0.933
1.307LysMet: 1.307 ± 0.649
0.871LysAsn: 0.871 ± 0.685
2.613LysPro: 2.613 ± 0.657
2.178LysGln: 2.178 ± 0.768
6.533LysArg: 6.533 ± 1.278
4.791LysSer: 4.791 ± 2.211
3.484LysThr: 3.484 ± 1.021
3.92LysVal: 3.92 ± 1.704
0.871LysTrp: 0.871 ± 0.492
2.613LysTyr: 2.613 ± 0.486
0.0LysXaa: 0.0 ± 0.0
Leu
4.791LeuAla: 4.791 ± 1.505
3.484LeuCys: 3.484 ± 1.837
5.226LeuAsp: 5.226 ± 1.534
2.613LeuGlu: 2.613 ± 1.301
4.355LeuPhe: 4.355 ± 1.689
6.969LeuGly: 6.969 ± 1.145
3.049LeuHis: 3.049 ± 0.812
2.613LeuIle: 2.613 ± 0.688
5.662LeuLys: 5.662 ± 1.199
9.146LeuLeu: 9.146 ± 1.834
1.742LeuMet: 1.742 ± 0.693
3.049LeuAsn: 3.049 ± 0.756
3.92LeuPro: 3.92 ± 0.704
5.226LeuGln: 5.226 ± 1.894
4.791LeuArg: 4.791 ± 1.171
10.017LeuSer: 10.017 ± 2.284
4.791LeuThr: 4.791 ± 0.892
4.355LeuVal: 4.355 ± 1.116
0.871LeuTrp: 0.871 ± 0.492
4.355LeuTyr: 4.355 ± 1.115
0.0LeuXaa: 0.0 ± 0.0
Met
1.307MetAla: 1.307 ± 0.769
0.871MetCys: 0.871 ± 0.752
0.871MetAsp: 0.871 ± 0.752
0.436MetGlu: 0.436 ± 0.657
0.436MetPhe: 0.436 ± 0.376
0.436MetGly: 0.436 ± 0.355
0.436MetHis: 0.436 ± 0.379
0.436MetIle: 0.436 ± 0.376
0.871MetLys: 0.871 ± 0.463
2.178MetLeu: 2.178 ± 1.392
0.436MetMet: 0.436 ± 0.379
0.871MetAsn: 0.871 ± 0.752
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.307MetArg: 1.307 ± 0.698
1.307MetSer: 1.307 ± 0.439
1.742MetThr: 1.742 ± 0.806
1.742MetVal: 1.742 ± 0.956
0.0MetTrp: 0.0 ± 0.0
0.436MetTyr: 0.436 ± 0.376
0.0MetXaa: 0.0 ± 0.0
Asn
2.613AsnAla: 2.613 ± 1.151
0.871AsnCys: 0.871 ± 1.315
1.307AsnAsp: 1.307 ± 0.432
1.742AsnGlu: 1.742 ± 0.277
1.307AsnPhe: 1.307 ± 0.935
2.613AsnGly: 2.613 ± 0.98
0.436AsnHis: 0.436 ± 0.355
1.307AsnIle: 1.307 ± 0.725
2.613AsnLys: 2.613 ± 0.841
5.226AsnLeu: 5.226 ± 2.495
0.871AsnMet: 0.871 ± 0.71
2.178AsnAsn: 2.178 ± 1.495
3.92AsnPro: 3.92 ± 1.543
1.742AsnGln: 1.742 ± 0.738
3.92AsnArg: 3.92 ± 1.053
3.92AsnSer: 3.92 ± 1.116
4.355AsnThr: 4.355 ± 1.403
1.742AsnVal: 1.742 ± 1.42
0.436AsnTrp: 0.436 ± 0.664
1.742AsnTyr: 1.742 ± 1.054
0.0AsnXaa: 0.0 ± 0.0
Pro
6.098ProAla: 6.098 ± 2.05
0.871ProCys: 0.871 ± 0.71
5.662ProAsp: 5.662 ± 1.296
3.92ProGlu: 3.92 ± 0.496
1.742ProPhe: 1.742 ± 0.87
2.178ProGly: 2.178 ± 0.482
0.0ProHis: 0.0 ± 0.0
2.178ProIle: 2.178 ± 0.671
3.049ProLys: 3.049 ± 0.756
5.662ProLeu: 5.662 ± 1.421
0.0ProMet: 0.0 ± 0.0
3.049ProAsn: 3.049 ± 1.651
4.791ProPro: 4.791 ± 1.187
2.178ProGln: 2.178 ± 0.944
3.049ProArg: 3.049 ± 1.755
5.662ProSer: 5.662 ± 2.207
1.742ProThr: 1.742 ± 1.048
4.791ProVal: 4.791 ± 0.846
0.871ProTrp: 0.871 ± 0.759
1.742ProTyr: 1.742 ± 0.956
0.0ProXaa: 0.0 ± 0.0
Gln
1.742GlnAla: 1.742 ± 0.806
0.871GlnCys: 0.871 ± 1.101
2.613GlnAsp: 2.613 ± 0.893
3.049GlnGlu: 3.049 ± 1.49
0.871GlnPhe: 0.871 ± 0.435
2.613GlnGly: 2.613 ± 0.489
0.436GlnHis: 0.436 ± 0.376
1.742GlnIle: 1.742 ± 0.656
0.436GlnLys: 0.436 ± 0.368
3.92GlnLeu: 3.92 ± 1.909
1.742GlnMet: 1.742 ± 0.974
0.871GlnAsn: 0.871 ± 0.435
1.307GlnPro: 1.307 ± 0.672
2.178GlnGln: 2.178 ± 0.704
1.742GlnArg: 1.742 ± 0.704
3.049GlnSer: 3.049 ± 0.495
4.791GlnThr: 4.791 ± 1.741
3.049GlnVal: 3.049 ± 0.689
2.178GlnTrp: 2.178 ± 0.973
0.436GlnTyr: 0.436 ± 0.355
0.0GlnXaa: 0.0 ± 0.0
Arg
3.484ArgAla: 3.484 ± 0.898
0.436ArgCys: 0.436 ± 0.657
2.178ArgAsp: 2.178 ± 0.586
3.484ArgGlu: 3.484 ± 0.958
2.613ArgPhe: 2.613 ± 1.116
7.404ArgGly: 7.404 ± 2.842
2.613ArgHis: 2.613 ± 0.865
0.871ArgIle: 0.871 ± 0.737
3.484ArgLys: 3.484 ± 0.863
5.226ArgLeu: 5.226 ± 1.287
1.307ArgMet: 1.307 ± 0.483
4.355ArgAsn: 4.355 ± 1.226
2.178ArgPro: 2.178 ± 1.143
4.791ArgGln: 4.791 ± 1.499
3.92ArgArg: 3.92 ± 0.871
3.049ArgSer: 3.049 ± 0.606
3.484ArgThr: 3.484 ± 1.1
4.355ArgVal: 4.355 ± 1.898
0.436ArgTrp: 0.436 ± 0.657
0.871ArgTyr: 0.871 ± 0.461
0.0ArgXaa: 0.0 ± 0.0
Ser
3.049SerAla: 3.049 ± 1.048
2.178SerCys: 2.178 ± 1.447
4.791SerAsp: 4.791 ± 1.266
6.098SerGlu: 6.098 ± 0.905
3.049SerPhe: 3.049 ± 0.834
6.533SerGly: 6.533 ± 0.788
2.178SerHis: 2.178 ± 1.049
3.049SerIle: 3.049 ± 1.334
4.791SerLys: 4.791 ± 1.187
7.404SerLeu: 7.404 ± 2.41
0.436SerMet: 0.436 ± 0.355
3.92SerAsn: 3.92 ± 0.943
6.098SerPro: 6.098 ± 1.857
2.178SerGln: 2.178 ± 0.801
4.355SerArg: 4.355 ± 1.434
9.146SerSer: 9.146 ± 2.332
7.84SerThr: 7.84 ± 2.042
6.533SerVal: 6.533 ± 2.327
0.436SerTrp: 0.436 ± 0.355
2.613SerTyr: 2.613 ± 0.864
0.0SerXaa: 0.0 ± 0.0
Thr
1.307ThrAla: 1.307 ± 0.69
2.178ThrCys: 2.178 ± 1.081
3.049ThrAsp: 3.049 ± 0.829
4.791ThrGlu: 4.791 ± 1.02
1.742ThrPhe: 1.742 ± 0.656
6.098ThrGly: 6.098 ± 1.44
0.436ThrHis: 0.436 ± 0.368
3.484ThrIle: 3.484 ± 1.331
1.742ThrLys: 1.742 ± 0.914
7.84ThrLeu: 7.84 ± 1.343
1.307ThrMet: 1.307 ± 0.733
4.355ThrAsn: 4.355 ± 2.005
3.484ThrPro: 3.484 ± 0.671
3.049ThrGln: 3.049 ± 0.955
3.92ThrArg: 3.92 ± 1.368
6.533ThrSer: 6.533 ± 1.625
3.484ThrThr: 3.484 ± 0.671
5.662ThrVal: 5.662 ± 1.264
0.0ThrTrp: 0.0 ± 0.0
2.178ThrTyr: 2.178 ± 0.671
0.0ThrXaa: 0.0 ± 0.0
Val
2.178ValAla: 2.178 ± 0.717
0.436ValCys: 0.436 ± 0.355
6.098ValAsp: 6.098 ± 1.366
3.049ValGlu: 3.049 ± 1.13
3.92ValPhe: 3.92 ± 1.952
5.662ValGly: 5.662 ± 0.585
0.436ValHis: 0.436 ± 0.368
3.049ValIle: 3.049 ± 0.94
3.484ValLys: 3.484 ± 1.514
2.178ValLeu: 2.178 ± 0.732
0.436ValMet: 0.436 ± 0.379
1.307ValAsn: 1.307 ± 0.669
3.484ValPro: 3.484 ± 1.592
3.049ValGln: 3.049 ± 1.466
3.92ValArg: 3.92 ± 0.717
8.711ValSer: 8.711 ± 1.77
3.484ValThr: 3.484 ± 0.847
3.049ValVal: 3.049 ± 1.182
0.871ValTrp: 0.871 ± 0.384
3.484ValTyr: 3.484 ± 0.552
0.0ValXaa: 0.0 ± 0.0
Trp
0.436TrpAla: 0.436 ± 0.355
0.436TrpCys: 0.436 ± 0.657
0.871TrpAsp: 0.871 ± 0.492
1.307TrpGlu: 1.307 ± 0.781
0.0TrpPhe: 0.0 ± 0.0
0.871TrpGly: 0.871 ± 0.492
0.0TrpHis: 0.0 ± 0.0
0.436TrpIle: 0.436 ± 0.355
1.307TrpLys: 1.307 ± 0.672
2.613TrpLeu: 2.613 ± 0.736
0.0TrpMet: 0.0 ± 0.0
0.436TrpAsn: 0.436 ± 0.376
0.436TrpPro: 0.436 ± 0.376
0.871TrpGln: 0.871 ± 0.702
0.436TrpArg: 0.436 ± 0.657
0.0TrpSer: 0.0 ± 0.0
0.871TrpThr: 0.871 ± 0.463
0.871TrpVal: 0.871 ± 0.71
0.0TrpTrp: 0.0 ± 0.0
1.307TrpTyr: 1.307 ± 0.733
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.742TyrAla: 1.742 ± 0.625
0.436TyrCys: 0.436 ± 0.355
0.871TyrAsp: 0.871 ± 0.384
2.613TyrGlu: 2.613 ± 1.064
0.871TyrPhe: 0.871 ± 0.752
3.049TyrGly: 3.049 ± 0.992
0.436TyrHis: 0.436 ± 0.355
1.742TyrIle: 1.742 ± 0.956
3.049TyrLys: 3.049 ± 1.245
1.742TyrLeu: 1.742 ± 0.572
0.871TyrMet: 0.871 ± 0.463
1.742TyrAsn: 1.742 ± 1.048
1.307TyrPro: 1.307 ± 0.432
2.178TyrGln: 2.178 ± 0.671
1.742TyrArg: 1.742 ± 1.048
1.307TyrSer: 1.307 ± 1.105
3.484TyrThr: 3.484 ± 1.012
3.049TyrVal: 3.049 ± 1.087
0.436TyrTrp: 0.436 ± 0.376
1.742TyrTyr: 1.742 ± 1.144
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2297 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski