Amino acid dipepetide frequency for Tetradesmus obliquus (Green alga) (Acutodesmus obliquus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	56.315AlaAla: 56.315 ± 0.375	2.184AlaCys: 2.184 ± 0.019	6.583AlaAsp: 6.583 ± 0.039	7.027AlaGlu: 7.027 ± 0.051	2.692AlaPhe: 2.692 ± 0.02	15.156AlaGly: 15.156 ± 0.06	2.117AlaHis: 2.117 ± 0.016	2.689AlaIle: 2.689 ± 0.019	3.802AlaLys: 3.802 ± 0.025	10.977AlaLeu: 10.977 ± 0.056	2.488AlaMet: 2.488 ± 0.016	2.602AlaAsn: 2.602 ± 0.017	7.089AlaPro: 7.089 ± 0.045	5.868AlaGln: 5.868 ± 0.037	5.693AlaArg: 5.693 ± 0.031	9.906AlaSer: 9.906 ± 0.046	6.309AlaThr: 6.309 ± 0.039	10.147AlaVal: 10.147 ± 0.046	1.534AlaTrp: 1.534 ± 0.018	1.936AlaTyr: 1.936 ± 0.015	0.002AlaXaa: 0.002 ± 0.0
Cys	1.581CysAla: 1.581 ± 0.015	0.714CysCys: 0.714 ± 0.015	0.699CysAsp: 0.699 ± 0.009	0.664CysGlu: 0.664 ± 0.01	0.511CysPhe: 0.511 ± 0.007	1.437CysGly: 1.437 ± 0.016	0.341CysHis: 0.341 ± 0.007	0.583CysIle: 0.583 ± 0.008	0.719CysLys: 0.719 ± 0.011	1.607CysLeu: 1.607 ± 0.015	0.448CysMet: 0.448 ± 0.006	0.594CysAsn: 0.594 ± 0.011	1.019CysPro: 1.019 ± 0.018	0.751CysGln: 0.751 ± 0.01	1.002CysArg: 1.002 ± 0.012	2.146CysSer: 2.146 ± 0.021	0.973CysThr: 0.973 ± 0.016	1.06CysVal: 1.06 ± 0.012	0.312CysTrp: 0.312 ± 0.006	0.397CysTyr: 0.397 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	6.483AspAla: 6.483 ± 0.031	0.754AspCys: 0.754 ± 0.012	2.892AspAsp: 2.892 ± 0.03	2.787AspGlu: 2.787 ± 0.027	1.183AspPhe: 1.183 ± 0.012	3.699AspGly: 3.699 ± 0.026	0.656AspHis: 0.656 ± 0.009	1.472AspIle: 1.472 ± 0.013	1.555AspLys: 1.555 ± 0.018	3.506AspLeu: 3.506 ± 0.022	1.083AspMet: 1.083 ± 0.011	1.108AspAsn: 1.108 ± 0.012	2.253AspPro: 2.253 ± 0.018	1.425AspGln: 1.425 ± 0.012	1.801AspArg: 1.801 ± 0.02	3.423AspSer: 3.423 ± 0.025	2.082AspThr: 2.082 ± 0.019	3.25AspVal: 3.25 ± 0.019	0.649AspTrp: 0.649 ± 0.008	0.924AspTyr: 0.924 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	7.101GluAla: 7.101 ± 0.045	0.632GluCys: 0.632 ± 0.01	2.469GluAsp: 2.469 ± 0.023	3.59GluGlu: 3.59 ± 0.033	1.053GluPhe: 1.053 ± 0.012	3.44GluGly: 3.44 ± 0.022	1.031GluHis: 1.031 ± 0.011	0.94GluIle: 0.94 ± 0.01	1.38GluLys: 1.38 ± 0.016	5.311GluLeu: 5.311 ± 0.034	0.894GluMet: 0.894 ± 0.01	0.685GluAsn: 0.685 ± 0.008	2.28GluPro: 2.28 ± 0.019	4.148GluGln: 4.148 ± 0.033	2.459GluArg: 2.459 ± 0.023	2.079GluSer: 2.079 ± 0.024	1.412GluThr: 1.412 ± 0.013	3.236GluVal: 3.236 ± 0.021	0.564GluTrp: 0.564 ± 0.008	0.875GluTyr: 0.875 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	2.493PheAla: 2.493 ± 0.016	0.493PheCys: 0.493 ± 0.008	1.354PheAsp: 1.354 ± 0.012	1.228PheGlu: 1.228 ± 0.013	0.771PhePhe: 0.771 ± 0.011	2.158PheGly: 2.158 ± 0.021	0.42PheHis: 0.42 ± 0.007	0.758PheIle: 0.758 ± 0.01	1.083PheLys: 1.083 ± 0.012	1.9PheLeu: 1.9 ± 0.017	0.583PheMet: 0.583 ± 0.007	0.865PheAsn: 0.865 ± 0.011	1.025PhePro: 1.025 ± 0.012	0.856PheGln: 0.856 ± 0.01	1.131PheArg: 1.131 ± 0.012	1.941PheSer: 1.941 ± 0.016	1.376PheThr: 1.376 ± 0.016	1.621PheVal: 1.621 ± 0.015	0.362PheTrp: 0.362 ± 0.006	0.596PheTyr: 0.596 ± 0.008	0.0PheXaa: 0.0 ± 0.0
Gly	9.779GlyAla: 9.779 ± 0.043	1.649GlyCys: 1.649 ± 0.014	3.487GlyAsp: 3.487 ± 0.027	3.054GlyGlu: 3.054 ± 0.021	2.264GlyPhe: 2.264 ± 0.018	9.354GlyGly: 9.354 ± 0.068	1.546GlyHis: 1.546 ± 0.014	2.158GlyIle: 2.158 ± 0.017	2.775GlyLys: 2.775 ± 0.022	7.381GlyLeu: 7.381 ± 0.037	1.957GlyMet: 1.957 ± 0.019	2.095GlyAsn: 2.095 ± 0.02	3.847GlyPro: 3.847 ± 0.027	3.866GlyGln: 3.866 ± 0.022	4.594GlyArg: 4.594 ± 0.032	10.189GlySer: 10.189 ± 0.053	3.867GlyThr: 3.867 ± 0.023	5.036GlyVal: 5.036 ± 0.027	1.236GlyTrp: 1.236 ± 0.013	1.74GlyTyr: 1.74 ± 0.019	0.001GlyXaa: 0.001 ± 0.0
His	2.506HisAla: 2.506 ± 0.018	0.444HisCys: 0.444 ± 0.007	0.843HisAsp: 0.843 ± 0.01	0.915HisGlu: 0.915 ± 0.009	0.563HisPhe: 0.563 ± 0.008	1.614HisGly: 1.614 ± 0.013	0.835HisHis: 0.835 ± 0.014	0.708HisIle: 0.708 ± 0.008	0.795HisLys: 0.795 ± 0.01	2.118HisLeu: 2.118 ± 0.018	0.615HisMet: 0.615 ± 0.009	0.605HisAsn: 0.605 ± 0.009	1.27HisPro: 1.27 ± 0.014	1.33HisGln: 1.33 ± 0.015	1.117HisArg: 1.117 ± 0.011	1.904HisSer: 1.904 ± 0.019	1.095HisThr: 1.095 ± 0.01	1.383HisVal: 1.383 ± 0.013	0.348HisTrp: 0.348 ± 0.006	0.475HisTyr: 0.475 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.92IleAla: 2.92 ± 0.02	0.476IleCys: 0.476 ± 0.007	1.32IleAsp: 1.32 ± 0.013	1.17IleGlu: 1.17 ± 0.013	0.653IlePhe: 0.653 ± 0.009	1.741IleGly: 1.741 ± 0.015	0.491IleHis: 0.491 ± 0.007	0.949IleIle: 0.949 ± 0.014	1.133IleLys: 1.133 ± 0.013	1.778IleLeu: 1.778 ± 0.017	0.576IleMet: 0.576 ± 0.009	0.942IleAsn: 0.942 ± 0.01	1.302IlePro: 1.302 ± 0.014	0.983IleGln: 0.983 ± 0.01	1.219IleArg: 1.219 ± 0.012	2.161IleSer: 2.161 ± 0.017	1.712IleThr: 1.712 ± 0.017	1.547IleVal: 1.547 ± 0.015	0.305IleTrp: 0.305 ± 0.006	0.508IleTyr: 0.508 ± 0.008	0.0IleXaa: 0.0 ± 0.0
Lys	4.255LysAla: 4.255 ± 0.029	0.466LysCys: 0.466 ± 0.008	1.434LysAsp: 1.434 ± 0.016	1.705LysGlu: 1.705 ± 0.018	0.738LysPhe: 0.738 ± 0.009	2.285LysGly: 2.285 ± 0.018	0.821LysHis: 0.821 ± 0.01	0.763LysIle: 0.763 ± 0.01	1.575LysLys: 1.575 ± 0.023	3.327LysLeu: 3.327 ± 0.023	0.586LysMet: 0.586 ± 0.009	0.643LysAsn: 0.643 ± 0.009	2.079LysPro: 2.079 ± 0.016	2.637LysGln: 2.637 ± 0.022	2.056LysArg: 2.056 ± 0.018	1.667LysSer: 1.667 ± 0.017	1.258LysThr: 1.258 ± 0.015	2.047LysVal: 2.047 ± 0.019	0.406LysTrp: 0.406 ± 0.006	0.678LysTyr: 0.678 ± 0.009	0.0LysXaa: 0.0 ± 0.0
Leu	12.064LeuAla: 12.064 ± 0.059	1.534LeuCys: 1.534 ± 0.015	4.063LeuAsp: 4.063 ± 0.023	4.475LeuGlu: 4.475 ± 0.03	2.143LeuPhe: 2.143 ± 0.019	6.408LeuGly: 6.408 ± 0.033	2.477LeuHis: 2.477 ± 0.017	1.915LeuIle: 1.915 ± 0.017	2.924LeuLys: 2.924 ± 0.022	13.239LeuLeu: 13.239 ± 0.084	1.888LeuMet: 1.888 ± 0.015	2.036LeuAsn: 2.036 ± 0.014	6.869LeuPro: 6.869 ± 0.046	9.054LeuGln: 9.054 ± 0.061	5.39LeuArg: 5.39 ± 0.031	6.475LeuSer: 6.475 ± 0.031	4.185LeuThr: 4.185 ± 0.029	5.546LeuVal: 5.546 ± 0.031	1.114LeuTrp: 1.114 ± 0.013	1.629LeuTyr: 1.629 ± 0.015	0.001LeuXaa: 0.001 ± 0.0
Met	2.586MetAla: 2.586 ± 0.017	0.329MetCys: 0.329 ± 0.006	0.881MetAsp: 0.881 ± 0.009	0.907MetGlu: 0.907 ± 0.01	0.537MetPhe: 0.537 ± 0.007	1.414MetGly: 1.414 ± 0.017	0.557MetHis: 0.557 ± 0.007	0.433MetIle: 0.433 ± 0.007	0.581MetLys: 0.581 ± 0.007	2.359MetLeu: 2.359 ± 0.017	0.56MetMet: 0.56 ± 0.009	0.413MetAsn: 0.413 ± 0.007	1.455MetPro: 1.455 ± 0.014	1.795MetGln: 1.795 ± 0.017	1.211MetArg: 1.211 ± 0.012	1.342MetSer: 1.342 ± 0.013	0.838MetThr: 0.838 ± 0.01	1.142MetVal: 1.142 ± 0.011	0.258MetTrp: 0.258 ± 0.005	0.426MetTyr: 0.426 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.755AsnAla: 2.755 ± 0.021	0.473AsnCys: 0.473 ± 0.009	0.945AsnAsp: 0.945 ± 0.01	0.876AsnGlu: 0.876 ± 0.01	0.667AsnPhe: 0.667 ± 0.011	1.986AsnGly: 1.986 ± 0.02	0.399AsnHis: 0.399 ± 0.006	0.933AsnIle: 0.933 ± 0.011	0.93AsnLys: 0.93 ± 0.012	1.929AsnLeu: 1.929 ± 0.015	0.605AsnMet: 0.605 ± 0.009	0.933AsnAsn: 0.933 ± 0.013	1.492AsnPro: 1.492 ± 0.014	0.822AsnGln: 0.822 ± 0.01	1.123AsnArg: 1.123 ± 0.01	2.437AsnSer: 2.437 ± 0.02	1.452AsnThr: 1.452 ± 0.016	1.465AsnVal: 1.465 ± 0.014	0.33AsnTrp: 0.33 ± 0.006	0.516AsnTyr: 0.516 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	10.65ProAla: 10.65 ± 0.062	0.887ProCys: 0.887 ± 0.012	2.525ProAsp: 2.525 ± 0.021	2.797ProGlu: 2.797 ± 0.019	1.289ProPhe: 1.289 ± 0.012	5.696ProGly: 5.696 ± 0.038	1.207ProHis: 1.207 ± 0.012	1.147ProIle: 1.147 ± 0.012	1.551ProLys: 1.551 ± 0.016	4.794ProLeu: 4.794 ± 0.027	0.873ProMet: 0.873 ± 0.011	1.25ProAsn: 1.25 ± 0.012	4.862ProPro: 4.862 ± 0.053	3.262ProGln: 3.262 ± 0.027	2.52ProArg: 2.52 ± 0.023	4.806ProSer: 4.806 ± 0.071	2.54ProThr: 2.54 ± 0.023	3.45ProVal: 3.45 ± 0.024	0.731ProTrp: 0.731 ± 0.009	0.999ProTyr: 0.999 ± 0.011	0.001ProXaa: 0.001 ± 0.0
Gln	7.049GlnAla: 7.049 ± 0.04	0.769GlnCys: 0.769 ± 0.011	2.041GlnAsp: 2.041 ± 0.014	3.234GlnGlu: 3.234 ± 0.029	0.931GlnPhe: 0.931 ± 0.011	3.844GlnGly: 3.844 ± 0.022	2.738GlnHis: 2.738 ± 0.026	0.934GlnIle: 0.934 ± 0.01	1.345GlnLys: 1.345 ± 0.015	9.534GlnLeu: 9.534 ± 0.066	1.113GlnMet: 1.113 ± 0.012	0.747GlnAsn: 0.747 ± 0.009	4.609GlnPro: 4.609 ± 0.036	27.211GlnGln: 27.211 ± 0.282	4.065GlnArg: 4.065 ± 0.025	2.384GlnSer: 2.384 ± 0.015	1.479GlnThr: 1.479 ± 0.013	3.114GlnVal: 3.114 ± 0.02	0.668GlnTrp: 0.668 ± 0.009	1.008GlnTyr: 1.008 ± 0.011	0.002GlnXaa: 0.002 ± 0.0
Arg	5.505ArgAla: 5.505 ± 0.028	1.069ArgCys: 1.069 ± 0.013	2.061ArgAsp: 2.061 ± 0.023	2.318ArgGlu: 2.318 ± 0.021	1.315ArgPhe: 1.315 ± 0.013	3.844ArgGly: 3.844 ± 0.029	1.437ArgHis: 1.437 ± 0.013	1.382ArgIle: 1.382 ± 0.013	1.93ArgLys: 1.93 ± 0.015	5.725ArgLeu: 5.725 ± 0.028	1.124ArgMet: 1.124 ± 0.01	1.186ArgAsn: 1.186 ± 0.011	2.919ArgPro: 2.919 ± 0.018	4.03ArgGln: 4.03 ± 0.026	4.08ArgArg: 4.08 ± 0.03	4.398ArgSer: 4.398 ± 0.033	2.064ArgThr: 2.064 ± 0.013	2.94ArgVal: 2.94 ± 0.018	0.74ArgTrp: 0.74 ± 0.009	1.067ArgTyr: 1.067 ± 0.011	0.001ArgXaa: 0.001 ± 0.0
Ser	9.565SerAla: 9.565 ± 0.042	1.862SerCys: 1.862 ± 0.02	3.092SerAsp: 3.092 ± 0.018	2.728SerGlu: 2.728 ± 0.019	2.005SerPhe: 2.005 ± 0.017	7.392SerGly: 7.392 ± 0.036	1.454SerHis: 1.454 ± 0.012	2.303SerIle: 2.303 ± 0.017	2.823SerLys: 2.823 ± 0.019	6.236SerLeu: 6.236 ± 0.037	1.736SerMet: 1.736 ± 0.015	2.659SerAsn: 2.659 ± 0.018	4.819SerPro: 4.819 ± 0.088	3.163SerGln: 3.163 ± 0.021	4.782SerArg: 4.782 ± 0.034	19.694SerSer: 19.694 ± 0.129	4.39SerThr: 4.39 ± 0.028	3.896SerVal: 3.896 ± 0.02	1.165SerTrp: 1.165 ± 0.013	1.426SerTyr: 1.426 ± 0.013	0.001SerXaa: 0.001 ± 0.0
Thr	7.909ThrAla: 7.909 ± 0.048	0.994ThrCys: 0.994 ± 0.019	1.83ThrAsp: 1.83 ± 0.018	1.667ThrGlu: 1.667 ± 0.013	1.189ThrPhe: 1.189 ± 0.013	3.816ThrGly: 3.816 ± 0.028	0.858ThrHis: 0.858 ± 0.011	1.314ThrIle: 1.314 ± 0.012	1.29ThrLys: 1.29 ± 0.012	3.79ThrLeu: 3.79 ± 0.026	0.747ThrMet: 0.747 ± 0.009	1.192ThrAsn: 1.192 ± 0.015	3.323ThrPro: 3.323 ± 0.029	1.921ThrGln: 1.921 ± 0.013	1.915ThrArg: 1.915 ± 0.014	3.711ThrSer: 3.711 ± 0.026	2.688ThrThr: 2.688 ± 0.031	2.789ThrVal: 2.789 ± 0.028	0.622ThrTrp: 0.622 ± 0.009	0.952ThrTyr: 0.952 ± 0.013	0.001ThrXaa: 0.001 ± 0.0
Val	8.445ValAla: 8.445 ± 0.036	1.147ValCys: 1.147 ± 0.013	2.83ValAsp: 2.83 ± 0.019	2.912ValGlu: 2.912 ± 0.018	1.613ValPhe: 1.613 ± 0.016	3.976ValGly: 3.976 ± 0.025	1.327ValHis: 1.327 ± 0.012	1.622ValIle: 1.622 ± 0.017	2.056ValLys: 2.056 ± 0.015	6.805ValLeu: 6.805 ± 0.035	1.365ValMet: 1.365 ± 0.011	1.509ValAsn: 1.509 ± 0.016	3.834ValPro: 3.834 ± 0.022	3.651ValGln: 3.651 ± 0.022	3.073ValArg: 3.073 ± 0.018	4.092ValSer: 4.092 ± 0.023	3.265ValThr: 3.265 ± 0.027	4.476ValVal: 4.476 ± 0.028	0.824ValTrp: 0.824 ± 0.01	1.249ValTyr: 1.249 ± 0.012	0.001ValXaa: 0.001 ± 0.0
Trp	1.267TrpAla: 1.267 ± 0.011	0.247TrpCys: 0.247 ± 0.005	0.641TrpAsp: 0.641 ± 0.009	0.598TrpGlu: 0.598 ± 0.008	0.345TrpPhe: 0.345 ± 0.006	1.009TrpGly: 1.009 ± 0.012	0.358TrpHis: 0.358 ± 0.007	0.264TrpIle: 0.264 ± 0.005	0.393TrpLys: 0.393 ± 0.006	1.526TrpLeu: 1.526 ± 0.016	0.312TrpMet: 0.312 ± 0.006	0.306TrpAsn: 0.306 ± 0.006	0.663TrpPro: 0.663 ± 0.01	1.203TrpGln: 1.203 ± 0.014	0.931TrpArg: 0.931 ± 0.011	0.891TrpSer: 0.891 ± 0.012	0.472TrpThr: 0.472 ± 0.007	0.739TrpVal: 0.739 ± 0.01	0.256TrpTrp: 0.256 ± 0.005	0.287TrpTyr: 0.287 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.884TyrAla: 1.884 ± 0.017	0.435TyrCys: 0.435 ± 0.007	0.995TyrAsp: 0.995 ± 0.012	0.928TyrGlu: 0.928 ± 0.011	0.553TyrPhe: 0.553 ± 0.008	1.607TyrGly: 1.607 ± 0.018	0.412TyrHis: 0.412 ± 0.006	0.621TyrIle: 0.621 ± 0.008	0.784TyrLys: 0.784 ± 0.011	1.585TyrLeu: 1.585 ± 0.013	0.47TyrMet: 0.47 ± 0.006	0.698TyrAsn: 0.698 ± 0.008	0.826TyrPro: 0.826 ± 0.011	0.842TyrGln: 0.842 ± 0.009	0.973TyrArg: 0.973 ± 0.011	1.54TyrSer: 1.54 ± 0.014	1.062TyrThr: 1.062 ± 0.012	1.192TyrVal: 1.192 ± 0.012	0.28TyrTrp: 0.28 ± 0.005	0.567TyrTyr: 0.567 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.007XaaXaa: 0.007 ± 0.002

Statistics based on 18538 proteins (10808351 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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