Amino acid dipepetide frequency for Hubei permutotetra-like virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.5AlaAla: 9.5 ± 1.828
0.633AlaCys: 0.633 ± 0.346
2.533AlaAsp: 2.533 ± 1.383
3.8AlaGlu: 3.8 ± 1.222
1.9AlaPhe: 1.9 ± 0.759
10.133AlaGly: 10.133 ± 0.802
1.267AlaHis: 1.267 ± 0.895
1.267AlaIle: 1.267 ± 0.691
3.167AlaLys: 3.167 ± 1.798
6.966AlaLeu: 6.966 ± 0.966
2.533AlaMet: 2.533 ± 2.797
3.8AlaAsn: 3.8 ± 1.705
3.8AlaPro: 3.8 ± 0.317
5.7AlaGln: 5.7 ± 2.059
8.233AlaArg: 8.233 ± 2.583
2.533AlaSer: 2.533 ± 1.383
3.8AlaThr: 3.8 ± 0.317
9.5AlaVal: 9.5 ± 2.695
0.633AlaTrp: 0.633 ± 0.346
3.8AlaTyr: 3.8 ± 0.317
0.0AlaXaa: 0.0 ± 0.0
Cys
0.633CysAla: 0.633 ± 1.125
0.0CysCys: 0.0 ± 0.0
0.633CysAsp: 0.633 ± 1.188
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.9CysGly: 1.9 ± 0.852
0.0CysHis: 0.0 ± 0.0
0.633CysIle: 0.633 ± 1.125
0.633CysLys: 0.633 ± 0.346
0.633CysLeu: 0.633 ± 0.346
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.633CysPro: 0.633 ± 0.346
0.0CysGln: 0.0 ± 0.0
0.633CysArg: 0.633 ± 0.346
1.267CysSer: 1.267 ± 0.691
0.0CysThr: 0.0 ± 0.0
0.633CysVal: 0.633 ± 1.125
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.8AspAla: 3.8 ± 0.317
1.267AspCys: 1.267 ± 0.691
2.533AspAsp: 2.533 ± 0.862
2.533AspGlu: 2.533 ± 0.998
5.066AspPhe: 5.066 ± 3.58
3.167AspGly: 3.167 ± 0.917
1.267AspHis: 1.267 ± 0.691
3.167AspIle: 3.167 ± 1.623
1.267AspLys: 1.267 ± 0.691
2.533AspLeu: 2.533 ± 1.383
1.267AspMet: 1.267 ± 0.691
1.267AspAsn: 1.267 ± 0.691
5.066AspPro: 5.066 ± 1.535
1.267AspGln: 1.267 ± 0.691
2.533AspArg: 2.533 ± 0.767
2.533AspSer: 2.533 ± 0.998
5.066AspThr: 5.066 ± 1.789
7.6AspVal: 7.6 ± 3.079
1.9AspTrp: 1.9 ± 0.852
1.9AspTyr: 1.9 ± 1.343
0.0AspXaa: 0.0 ± 0.0
Glu
8.866GluAla: 8.866 ± 3.724
0.0GluCys: 0.0 ± 0.0
5.066GluAsp: 5.066 ± 2.37
2.533GluGlu: 2.533 ± 0.862
0.633GluPhe: 0.633 ± 0.346
6.966GluGly: 6.966 ± 2.21
0.633GluHis: 0.633 ± 0.346
3.8GluIle: 3.8 ± 0.317
3.167GluLys: 3.167 ± 0.999
2.533GluLeu: 2.533 ± 1.383
1.267GluMet: 1.267 ± 2.375
0.0GluAsn: 0.0 ± 0.0
1.267GluPro: 1.267 ± 0.691
2.533GluGln: 2.533 ± 0.767
5.066GluArg: 5.066 ± 1.229
3.8GluSer: 3.8 ± 1.222
5.066GluThr: 5.066 ± 1.535
2.533GluVal: 2.533 ± 0.862
0.633GluTrp: 0.633 ± 1.125
0.633GluTyr: 0.633 ± 0.346
0.0GluXaa: 0.0 ± 0.0
Phe
1.267PheAla: 1.267 ± 0.691
0.0PheCys: 0.0 ± 0.0
1.9PheAsp: 1.9 ± 1.037
1.9PheGlu: 1.9 ± 1.343
0.633PhePhe: 0.633 ± 1.125
2.533PheGly: 2.533 ± 1.79
1.267PheHis: 1.267 ± 0.895
1.267PheIle: 1.267 ± 0.974
1.267PheLys: 1.267 ± 0.895
2.533PheLeu: 2.533 ± 1.383
1.267PheMet: 1.267 ± 0.691
1.267PheAsn: 1.267 ± 0.974
3.167PhePro: 3.167 ± 0.999
0.633PheGln: 0.633 ± 1.125
0.633PheArg: 0.633 ± 1.125
1.9PheSer: 1.9 ± 3.375
1.9PheThr: 1.9 ± 2.003
3.167PheVal: 3.167 ± 0.917
0.633PheTrp: 0.633 ± 0.346
0.633PheTyr: 0.633 ± 1.125
0.0PheXaa: 0.0 ± 0.0
Gly
6.966GlyAla: 6.966 ± 0.966
0.633GlyCys: 0.633 ± 1.188
4.433GlyAsp: 4.433 ± 1.486
5.7GlyGlu: 5.7 ± 1.834
2.533GlyPhe: 2.533 ± 0.998
6.333GlyGly: 6.333 ± 0.942
0.633GlyHis: 0.633 ± 0.346
3.167GlyIle: 3.167 ± 0.917
2.533GlyLys: 2.533 ± 1.383
8.233GlyLeu: 8.233 ± 4.338
1.267GlyMet: 1.267 ± 0.974
0.633GlyAsn: 0.633 ± 0.346
1.9GlyPro: 1.9 ± 1.037
1.9GlyGln: 1.9 ± 1.037
3.167GlyArg: 3.167 ± 0.917
3.8GlySer: 3.8 ± 1.758
6.333GlyThr: 6.333 ± 1.999
4.433GlyVal: 4.433 ± 2.42
0.633GlyTrp: 0.633 ± 0.346
3.8GlyTyr: 3.8 ± 1.154
0.0GlyXaa: 0.0 ± 0.0
His
1.9HisAla: 1.9 ± 1.037
0.633HisCys: 0.633 ± 1.125
1.267HisAsp: 1.267 ± 0.691
1.267HisGlu: 1.267 ± 0.691
1.267HisPhe: 1.267 ± 0.691
2.533HisGly: 2.533 ± 1.383
1.267HisHis: 1.267 ± 0.691
0.633HisIle: 0.633 ± 0.346
0.633HisLys: 0.633 ± 0.346
2.533HisLeu: 2.533 ± 1.79
1.267HisMet: 1.267 ± 0.974
0.633HisAsn: 0.633 ± 0.346
1.267HisPro: 1.267 ± 0.691
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.633HisSer: 0.633 ± 0.346
1.267HisThr: 1.267 ± 0.895
0.0HisVal: 0.0 ± 0.0
0.633HisTrp: 0.633 ± 1.188
1.267HisTyr: 1.267 ± 0.691
0.0HisXaa: 0.0 ± 0.0
Ile
1.267IleAla: 1.267 ± 0.691
0.633IleCys: 0.633 ± 0.346
2.533IleAsp: 2.533 ± 1.383
1.267IleGlu: 1.267 ± 0.895
0.0IlePhe: 0.0 ± 0.0
1.267IleGly: 1.267 ± 0.974
1.267IleHis: 1.267 ± 0.974
0.0IleIle: 0.0 ± 0.0
2.533IleLys: 2.533 ± 1.383
3.167IleLeu: 3.167 ± 4.247
0.633IleMet: 0.633 ± 0.346
1.267IleAsn: 1.267 ± 0.691
1.267IlePro: 1.267 ± 0.895
1.267IleGln: 1.267 ± 0.691
3.167IleArg: 3.167 ± 1.729
4.433IleSer: 4.433 ± 1.679
4.433IleThr: 4.433 ± 1.486
4.433IleVal: 4.433 ± 1.486
1.267IleTrp: 1.267 ± 0.974
2.533IleTyr: 2.533 ± 0.767
0.0IleXaa: 0.0 ± 0.0
Lys
3.8LysAla: 3.8 ± 1.222
1.267LysCys: 1.267 ± 0.974
2.533LysAsp: 2.533 ± 0.767
2.533LysGlu: 2.533 ± 1.383
3.167LysPhe: 3.167 ± 1.949
3.167LysGly: 3.167 ± 1.798
0.633LysHis: 0.633 ± 0.346
1.9LysIle: 1.9 ± 1.037
7.6LysLys: 7.6 ± 0.635
5.7LysLeu: 5.7 ± 2.059
1.9LysMet: 1.9 ± 0.852
1.9LysAsn: 1.9 ± 1.037
2.533LysPro: 2.533 ± 2.372
0.633LysGln: 0.633 ± 0.346
2.533LysArg: 2.533 ± 2.372
3.167LysSer: 3.167 ± 1.729
6.333LysThr: 6.333 ± 2.688
3.8LysVal: 3.8 ± 1.222
1.9LysTrp: 1.9 ± 0.852
1.267LysTyr: 1.267 ± 0.895
0.0LysXaa: 0.0 ± 0.0
Leu
5.7LeuAla: 5.7 ± 0.741
0.0LeuCys: 0.0 ± 0.0
4.433LeuAsp: 4.433 ± 1.436
7.6LeuGlu: 7.6 ± 2.309
4.433LeuPhe: 4.433 ± 1.486
3.8LeuGly: 3.8 ± 0.317
1.267LeuHis: 1.267 ± 0.895
3.8LeuIle: 3.8 ± 1.517
5.7LeuLys: 5.7 ± 2.154
6.966LeuLeu: 6.966 ± 3.803
1.9LeuMet: 1.9 ± 1.037
3.8LeuAsn: 3.8 ± 1.758
7.6LeuPro: 7.6 ± 2.586
1.9LeuGln: 1.9 ± 0.852
5.7LeuArg: 5.7 ± 1.039
6.966LeuSer: 6.966 ± 3.574
6.966LeuThr: 6.966 ± 2.372
5.066LeuVal: 5.066 ± 2.639
1.267LeuTrp: 1.267 ± 0.895
1.9LeuTyr: 1.9 ± 2.003
0.0LeuXaa: 0.0 ± 0.0
Met
2.533MetAla: 2.533 ± 1.383
1.267MetCys: 1.267 ± 0.691
3.167MetAsp: 3.167 ± 0.999
3.167MetGlu: 3.167 ± 0.999
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.633MetHis: 0.633 ± 0.346
1.9MetIle: 1.9 ± 0.759
1.267MetLys: 1.267 ± 0.895
3.8MetLeu: 3.8 ± 2.922
0.0MetMet: 0.0 ± 0.0
1.267MetAsn: 1.267 ± 0.691
0.633MetPro: 0.633 ± 0.346
0.633MetGln: 0.633 ± 0.346
4.433MetArg: 4.433 ± 1.486
1.267MetSer: 1.267 ± 2.375
2.533MetThr: 2.533 ± 1.948
1.9MetVal: 1.9 ± 0.852
0.0MetTrp: 0.0 ± 0.0
0.633MetTyr: 0.633 ± 0.346
0.0MetXaa: 0.0 ± 0.0
Asn
4.433AsnAla: 4.433 ± 1.486
0.0AsnCys: 0.0 ± 0.0
1.9AsnAsp: 1.9 ± 1.037
0.633AsnGlu: 0.633 ± 0.346
1.267AsnPhe: 1.267 ± 0.974
2.533AsnGly: 2.533 ± 0.862
1.267AsnHis: 1.267 ± 0.691
2.533AsnIle: 2.533 ± 0.998
1.267AsnLys: 1.267 ± 0.974
1.267AsnLeu: 1.267 ± 1.688
1.267AsnMet: 1.267 ± 0.691
1.9AsnAsn: 1.9 ± 0.759
1.9AsnPro: 1.9 ± 1.037
0.633AsnGln: 0.633 ± 0.346
0.0AsnArg: 0.0 ± 0.0
2.533AsnSer: 2.533 ± 1.948
3.8AsnThr: 3.8 ± 3.022
2.533AsnVal: 2.533 ± 0.767
0.633AsnTrp: 0.633 ± 1.188
1.267AsnTyr: 1.267 ± 0.691
0.0AsnXaa: 0.0 ± 0.0
Pro
3.167ProAla: 3.167 ± 0.917
0.633ProCys: 0.633 ± 1.125
5.066ProAsp: 5.066 ± 1.741
2.533ProGlu: 2.533 ± 0.767
0.633ProPhe: 0.633 ± 1.125
2.533ProGly: 2.533 ± 1.383
2.533ProHis: 2.533 ± 0.862
3.167ProIle: 3.167 ± 0.999
1.267ProLys: 1.267 ± 0.691
5.066ProLeu: 5.066 ± 1.535
1.9ProMet: 1.9 ± 1.037
1.9ProAsn: 1.9 ± 0.852
5.066ProPro: 5.066 ± 1.741
1.9ProGln: 1.9 ± 1.037
3.8ProArg: 3.8 ± 1.222
3.8ProSer: 3.8 ± 1.154
5.7ProThr: 5.7 ± 1.039
3.167ProVal: 3.167 ± 0.655
0.633ProTrp: 0.633 ± 1.188
2.533ProTyr: 2.533 ± 1.383
0.0ProXaa: 0.0 ± 0.0
Gln
2.533GlnAla: 2.533 ± 1.383
0.633GlnCys: 0.633 ± 1.125
1.267GlnAsp: 1.267 ± 0.691
1.9GlnGlu: 1.9 ± 0.759
1.9GlnPhe: 1.9 ± 2.003
3.167GlnGly: 3.167 ± 0.999
1.9GlnHis: 1.9 ± 1.037
0.0GlnIle: 0.0 ± 0.0
0.633GlnLys: 0.633 ± 1.188
3.167GlnLeu: 3.167 ± 1.623
1.267GlnMet: 1.267 ± 0.974
1.267GlnAsn: 1.267 ± 0.691
2.533GlnPro: 2.533 ± 1.383
1.9GlnGln: 1.9 ± 0.759
0.633GlnArg: 0.633 ± 0.346
0.633GlnSer: 0.633 ± 0.346
2.533GlnThr: 2.533 ± 0.767
3.167GlnVal: 3.167 ± 0.917
0.633GlnTrp: 0.633 ± 0.346
0.633GlnTyr: 0.633 ± 1.125
0.0GlnXaa: 0.0 ± 0.0
Arg
8.866ArgAla: 8.866 ± 1.508
0.0ArgCys: 0.0 ± 0.0
2.533ArgAsp: 2.533 ± 0.767
3.167ArgGlu: 3.167 ± 0.655
1.267ArgPhe: 1.267 ± 0.691
4.433ArgGly: 4.433 ± 1.486
0.633ArgHis: 0.633 ± 0.346
3.8ArgIle: 3.8 ± 1.154
4.433ArgLys: 4.433 ± 1.492
5.7ArgLeu: 5.7 ± 0.741
3.167ArgMet: 3.167 ± 0.952
2.533ArgAsn: 2.533 ± 0.998
3.8ArgPro: 3.8 ± 1.517
2.533ArgGln: 2.533 ± 2.278
8.233ArgArg: 8.233 ± 2.985
3.167ArgSer: 3.167 ± 0.917
5.7ArgThr: 5.7 ± 2.1
3.8ArgVal: 3.8 ± 1.517
0.0ArgTrp: 0.0 ± 0.0
2.533ArgTyr: 2.533 ± 1.948
0.0ArgXaa: 0.0 ± 0.0
Ser
5.7SerAla: 5.7 ± 2.557
0.0SerCys: 0.0 ± 0.0
3.8SerAsp: 3.8 ± 1.222
0.0SerGlu: 0.0 ± 0.0
2.533SerPhe: 2.533 ± 0.998
5.7SerGly: 5.7 ± 2.059
1.267SerHis: 1.267 ± 0.895
3.167SerIle: 3.167 ± 0.655
3.8SerLys: 3.8 ± 1.705
6.966SerLeu: 6.966 ± 2.21
1.267SerMet: 1.267 ± 0.691
2.533SerAsn: 2.533 ± 0.998
0.633SerPro: 0.633 ± 0.346
2.533SerGln: 2.533 ± 0.998
7.6SerArg: 7.6 ± 1.517
6.966SerSer: 6.966 ± 0.97
1.9SerThr: 1.9 ± 1.037
3.167SerVal: 3.167 ± 1.949
1.267SerTrp: 1.267 ± 0.691
1.9SerTyr: 1.9 ± 0.759
0.0SerXaa: 0.0 ± 0.0
Thr
5.7ThrAla: 5.7 ± 1.039
0.0ThrCys: 0.0 ± 0.0
3.8ThrAsp: 3.8 ± 1.627
6.966ThrGlu: 6.966 ± 2.21
1.267ThrPhe: 1.267 ± 0.691
4.433ThrGly: 4.433 ± 1.436
1.267ThrHis: 1.267 ± 0.691
0.633ThrIle: 0.633 ± 0.346
8.233ThrLys: 8.233 ± 3.366
5.066ThrLeu: 5.066 ± 2.661
1.9ThrMet: 1.9 ± 1.343
2.533ThrAsn: 2.533 ± 3.65
4.433ThrPro: 4.433 ± 1.492
2.533ThrGln: 2.533 ± 1.79
6.966ThrArg: 6.966 ± 0.97
5.7ThrSer: 5.7 ± 1.655
6.966ThrThr: 6.966 ± 3.373
6.333ThrVal: 6.333 ± 0.656
1.267ThrTrp: 1.267 ± 0.691
2.533ThrTyr: 2.533 ± 1.383
0.0ThrXaa: 0.0 ± 0.0
Val
8.233ValAla: 8.233 ± 3.984
0.0ValCys: 0.0 ± 0.0
3.8ValAsp: 3.8 ± 2.686
6.966ValGlu: 6.966 ± 2.056
0.633ValPhe: 0.633 ± 0.346
3.8ValGly: 3.8 ± 1.705
1.267ValHis: 1.267 ± 0.691
2.533ValIle: 2.533 ± 1.383
4.433ValLys: 4.433 ± 1.486
10.766ValLeu: 10.766 ± 2.615
1.9ValMet: 1.9 ± 1.037
1.9ValAsn: 1.9 ± 0.759
6.966ValPro: 6.966 ± 2.716
3.167ValGln: 3.167 ± 0.917
3.167ValArg: 3.167 ± 0.999
1.9ValSer: 1.9 ± 0.759
3.8ValThr: 3.8 ± 1.758
8.233ValVal: 8.233 ± 1.321
0.633ValTrp: 0.633 ± 0.346
1.9ValTyr: 1.9 ± 0.759
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.633TrpAsp: 0.633 ± 1.125
1.267TrpGlu: 1.267 ± 0.691
0.633TrpPhe: 0.633 ± 0.346
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.633TrpLys: 0.633 ± 1.188
1.267TrpLeu: 1.267 ± 0.974
1.9TrpMet: 1.9 ± 1.037
0.633TrpAsn: 0.633 ± 0.346
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.9TrpArg: 1.9 ± 0.852
1.9TrpSer: 1.9 ± 0.852
2.533TrpThr: 2.533 ± 0.767
0.633TrpVal: 0.633 ± 1.188
0.0TrpTrp: 0.0 ± 0.0
0.633TrpTyr: 0.633 ± 1.188
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.267TyrAla: 1.267 ± 1.688
0.633TyrCys: 0.633 ± 0.346
3.167TyrAsp: 3.167 ± 0.999
1.267TyrGlu: 1.267 ± 0.974
0.0TyrPhe: 0.0 ± 0.0
0.633TyrGly: 0.633 ± 0.346
0.633TyrHis: 0.633 ± 0.346
1.267TyrIle: 1.267 ± 0.691
3.8TyrLys: 3.8 ± 1.627
1.9TyrLeu: 1.9 ± 1.037
2.533TyrMet: 2.533 ± 0.794
2.533TyrAsn: 2.533 ± 0.767
2.533TyrPro: 2.533 ± 1.79
0.633TyrGln: 0.633 ± 0.346
1.9TyrArg: 1.9 ± 0.759
3.8TyrSer: 3.8 ± 0.317
1.9TyrThr: 1.9 ± 0.759
1.9TyrVal: 1.9 ± 0.759
0.0TyrTrp: 0.0 ± 0.0
0.633TyrTyr: 0.633 ± 0.346
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1580 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski