Amino acid dipepetide frequency for Chromatocurvus halotolerans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.36AlaAla: 14.36 ± 0.188	1.273AlaCys: 1.273 ± 0.033	6.98AlaAsp: 6.98 ± 0.076	6.987AlaGlu: 6.987 ± 0.088	3.856AlaPhe: 3.856 ± 0.062	10.119AlaGly: 10.119 ± 0.108	2.173AlaHis: 2.173 ± 0.047	5.354AlaIle: 5.354 ± 0.073	2.151AlaLys: 2.151 ± 0.052	13.386AlaLeu: 13.386 ± 0.128	3.193AlaMet: 3.193 ± 0.05	2.586AlaAsn: 2.586 ± 0.049	4.809AlaPro: 4.809 ± 0.078	4.129AlaGln: 4.129 ± 0.061	8.481AlaArg: 8.481 ± 0.107	6.719AlaSer: 6.719 ± 0.085	5.554AlaThr: 5.554 ± 0.074	8.243AlaVal: 8.243 ± 0.094	1.552AlaTrp: 1.552 ± 0.041	2.456AlaTyr: 2.456 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.1CysAla: 1.1 ± 0.034	0.145CysCys: 0.145 ± 0.012	0.571CysAsp: 0.571 ± 0.024	0.549CysGlu: 0.549 ± 0.021	0.342CysPhe: 0.342 ± 0.017	0.938CysGly: 0.938 ± 0.029	0.322CysHis: 0.322 ± 0.022	0.465CysIle: 0.465 ± 0.02	0.155CysLys: 0.155 ± 0.011	1.063CysLeu: 1.063 ± 0.028	0.186CysMet: 0.186 ± 0.012	0.25CysAsn: 0.25 ± 0.015	0.51CysPro: 0.51 ± 0.024	0.302CysGln: 0.302 ± 0.016	0.785CysArg: 0.785 ± 0.029	0.613CysSer: 0.613 ± 0.027	0.419CysThr: 0.419 ± 0.019	0.682CysVal: 0.682 ± 0.025	0.116CysTrp: 0.116 ± 0.01	0.244CysTyr: 0.244 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.403AspAla: 7.403 ± 0.088	0.598AspCys: 0.598 ± 0.026	3.962AspAsp: 3.962 ± 0.072	3.605AspGlu: 3.605 ± 0.057	2.442AspPhe: 2.442 ± 0.052	5.212AspGly: 5.212 ± 0.077	1.245AspHis: 1.245 ± 0.032	3.517AspIle: 3.517 ± 0.06	1.298AspLys: 1.298 ± 0.041	5.964AspLeu: 5.964 ± 0.069	1.507AspMet: 1.507 ± 0.034	1.986AspAsn: 1.986 ± 0.046	3.296AspPro: 3.296 ± 0.062	1.698AspGln: 1.698 ± 0.039	4.317AspArg: 4.317 ± 0.067	3.645AspSer: 3.645 ± 0.063	3.194AspThr: 3.194 ± 0.062	4.342AspVal: 4.342 ± 0.06	1.1AspTrp: 1.1 ± 0.035	1.987AspTyr: 1.987 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	6.822GluAla: 6.822 ± 0.09	0.387GluCys: 0.387 ± 0.019	3.254GluAsp: 3.254 ± 0.059	3.429GluGlu: 3.429 ± 0.067	1.915GluPhe: 1.915 ± 0.039	4.243GluGly: 4.243 ± 0.058	1.539GluHis: 1.539 ± 0.044	2.964GluIle: 2.964 ± 0.053	1.87GluLys: 1.87 ± 0.045	6.312GluLeu: 6.312 ± 0.087	1.318GluMet: 1.318 ± 0.033	1.764GluAsn: 1.764 ± 0.041	2.68GluPro: 2.68 ± 0.05	2.86GluGln: 2.86 ± 0.052	5.042GluArg: 5.042 ± 0.077	3.534GluSer: 3.534 ± 0.06	3.269GluThr: 3.269 ± 0.052	3.989GluVal: 3.989 ± 0.06	0.778GluTrp: 0.778 ± 0.026	1.289GluTyr: 1.289 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.948PheAla: 3.948 ± 0.061	0.404PheCys: 0.404 ± 0.019	2.574PheAsp: 2.574 ± 0.056	1.967PheGlu: 1.967 ± 0.039	1.439PhePhe: 1.439 ± 0.042	3.152PheGly: 3.152 ± 0.053	0.811PheHis: 0.811 ± 0.027	1.757PheIle: 1.757 ± 0.044	0.75PheLys: 0.75 ± 0.022	3.422PheLeu: 3.422 ± 0.07	0.855PheMet: 0.855 ± 0.026	1.205PheAsn: 1.205 ± 0.03	1.526PhePro: 1.526 ± 0.037	1.063PheGln: 1.063 ± 0.029	2.321PheArg: 2.321 ± 0.038	2.559PheSer: 2.559 ± 0.058	2.074PheThr: 2.074 ± 0.047	2.338PheVal: 2.338 ± 0.049	0.48PheTrp: 0.48 ± 0.019	1.064PheTyr: 1.064 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	7.855GlyAla: 7.855 ± 0.088	0.922GlyCys: 0.922 ± 0.03	5.262GlyAsp: 5.262 ± 0.077	5.159GlyGlu: 5.159 ± 0.07	3.355GlyPhe: 3.355 ± 0.056	6.565GlyGly: 6.565 ± 0.093	1.84GlyHis: 1.84 ± 0.04	4.435GlyIle: 4.435 ± 0.07	2.558GlyLys: 2.558 ± 0.06	8.346GlyLeu: 8.346 ± 0.105	2.345GlyMet: 2.345 ± 0.045	2.528GlyAsn: 2.528 ± 0.056	2.848GlyPro: 2.848 ± 0.052	2.67GlyGln: 2.67 ± 0.052	5.778GlyArg: 5.778 ± 0.084	5.151GlySer: 5.151 ± 0.08	4.232GlyThr: 4.232 ± 0.071	6.241GlyVal: 6.241 ± 0.079	1.235GlyTrp: 1.235 ± 0.033	2.431GlyTyr: 2.431 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.36HisAla: 2.36 ± 0.043	0.327HisCys: 0.327 ± 0.016	1.23HisAsp: 1.23 ± 0.029	1.138HisGlu: 1.138 ± 0.032	0.887HisPhe: 0.887 ± 0.03	1.928HisGly: 1.928 ± 0.04	0.642HisHis: 0.642 ± 0.026	1.05HisIle: 1.05 ± 0.027	0.416HisLys: 0.416 ± 0.02	2.275HisLeu: 2.275 ± 0.049	0.478HisMet: 0.478 ± 0.02	0.571HisAsn: 0.571 ± 0.024	1.466HisPro: 1.466 ± 0.036	0.722HisGln: 0.722 ± 0.024	1.804HisArg: 1.804 ± 0.044	1.217HisSer: 1.217 ± 0.031	1.049HisThr: 1.049 ± 0.027	1.413HisVal: 1.413 ± 0.035	0.476HisTrp: 0.476 ± 0.022	0.804HisTyr: 0.804 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.144IleAla: 6.144 ± 0.077	0.437IleCys: 0.437 ± 0.019	3.758IleAsp: 3.758 ± 0.058	3.136IleGlu: 3.136 ± 0.058	1.416IlePhe: 1.416 ± 0.037	4.047IleGly: 4.047 ± 0.058	1.01IleHis: 1.01 ± 0.028	2.101IleIle: 2.101 ± 0.047	1.095IleLys: 1.095 ± 0.034	4.131IleLeu: 4.131 ± 0.065	0.91IleMet: 0.91 ± 0.03	1.697IleAsn: 1.697 ± 0.035	2.268IlePro: 2.268 ± 0.046	1.281IleGln: 1.281 ± 0.034	3.189IleArg: 3.189 ± 0.054	2.858IleSer: 2.858 ± 0.05	2.718IleThr: 2.718 ± 0.044	3.298IleVal: 3.298 ± 0.06	0.501IleTrp: 0.501 ± 0.023	1.12IleTyr: 1.12 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	2.653LysAla: 2.653 ± 0.058	0.168LysCys: 0.168 ± 0.015	1.227LysAsp: 1.227 ± 0.038	1.174LysGlu: 1.174 ± 0.035	0.651LysPhe: 0.651 ± 0.025	1.727LysGly: 1.727 ± 0.043	0.542LysHis: 0.542 ± 0.024	1.027LysIle: 1.027 ± 0.031	0.941LysLys: 0.941 ± 0.036	2.336LysLeu: 2.336 ± 0.054	0.545LysMet: 0.545 ± 0.023	0.68LysAsn: 0.68 ± 0.029	1.389LysPro: 1.389 ± 0.033	0.952LysGln: 0.952 ± 0.026	1.91LysArg: 1.91 ± 0.045	1.373LysSer: 1.373 ± 0.041	1.512LysThr: 1.512 ± 0.037	1.68LysVal: 1.68 ± 0.042	0.258LysTrp: 0.258 ± 0.018	0.57LysTyr: 0.57 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	13.321LeuAla: 13.321 ± 0.155	1.126LeuCys: 1.126 ± 0.033	6.588LeuAsp: 6.588 ± 0.075	6.385LeuGlu: 6.385 ± 0.082	3.859LeuPhe: 3.859 ± 0.069	8.232LeuGly: 8.232 ± 0.096	2.338LeuHis: 2.338 ± 0.046	4.429LeuIle: 4.429 ± 0.075	2.658LeuLys: 2.658 ± 0.059	12.058LeuLeu: 12.058 ± 0.148	2.425LeuMet: 2.425 ± 0.053	2.752LeuAsn: 2.752 ± 0.053	6.012LeuPro: 6.012 ± 0.081	4.558LeuGln: 4.558 ± 0.075	8.138LeuArg: 8.138 ± 0.094	6.855LeuSer: 6.855 ± 0.08	5.342LeuThr: 5.342 ± 0.07	7.723LeuVal: 7.723 ± 0.106	1.384LeuTrp: 1.384 ± 0.034	2.535LeuTyr: 2.535 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.789MetAla: 2.789 ± 0.051	0.165MetCys: 0.165 ± 0.011	1.258MetAsp: 1.258 ± 0.031	1.168MetGlu: 1.168 ± 0.034	0.622MetPhe: 0.622 ± 0.023	1.71MetGly: 1.71 ± 0.041	0.513MetHis: 0.513 ± 0.021	1.088MetIle: 1.088 ± 0.033	0.732MetLys: 0.732 ± 0.027	2.706MetLeu: 2.706 ± 0.051	0.525MetMet: 0.525 ± 0.024	0.802MetAsn: 0.802 ± 0.028	1.406MetPro: 1.406 ± 0.032	1.139MetGln: 1.139 ± 0.035	1.747MetArg: 1.747 ± 0.042	1.554MetSer: 1.554 ± 0.035	1.579MetThr: 1.579 ± 0.034	1.484MetVal: 1.484 ± 0.037	0.18MetTrp: 0.18 ± 0.014	0.405MetTyr: 0.405 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.243AsnAla: 3.243 ± 0.05	0.254AsnCys: 0.254 ± 0.015	1.62AsnAsp: 1.62 ± 0.041	1.382AsnGlu: 1.382 ± 0.038	0.954AsnPhe: 0.954 ± 0.028	2.235AsnGly: 2.235 ± 0.049	0.591AsnHis: 0.591 ± 0.021	1.436AsnIle: 1.436 ± 0.04	0.554AsnLys: 0.554 ± 0.022	2.875AsnLeu: 2.875 ± 0.056	0.601AsnMet: 0.601 ± 0.025	0.854AsnAsn: 0.854 ± 0.031	1.914AsnPro: 1.914 ± 0.039	0.83AsnGln: 0.83 ± 0.031	2.144AsnArg: 2.144 ± 0.038	1.499AsnSer: 1.499 ± 0.04	1.578AsnThr: 1.578 ± 0.033	1.957AsnVal: 1.957 ± 0.044	0.404AsnTrp: 0.404 ± 0.018	0.79AsnTyr: 0.79 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	5.881ProAla: 5.881 ± 0.08	0.358ProCys: 0.358 ± 0.019	3.731ProAsp: 3.731 ± 0.07	3.721ProGlu: 3.721 ± 0.059	1.691ProPhe: 1.691 ± 0.042	4.848ProGly: 4.848 ± 0.073	0.989ProHis: 0.989 ± 0.031	1.785ProIle: 1.785 ± 0.036	0.885ProLys: 0.885 ± 0.028	5.152ProLeu: 5.152 ± 0.073	1.127ProMet: 1.127 ± 0.031	1.083ProAsn: 1.083 ± 0.03	2.391ProPro: 2.391 ± 0.064	1.774ProGln: 1.774 ± 0.036	3.114ProArg: 3.114 ± 0.055	2.42ProSer: 2.42 ± 0.045	2.208ProThr: 2.208 ± 0.043	4.092ProVal: 4.092 ± 0.064	0.735ProTrp: 0.735 ± 0.028	1.071ProTyr: 1.071 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.446GlnAla: 4.446 ± 0.077	0.292GlnCys: 0.292 ± 0.017	1.754GlnAsp: 1.754 ± 0.036	1.915GlnGlu: 1.915 ± 0.041	1.2GlnPhe: 1.2 ± 0.028	2.62GlnGly: 2.62 ± 0.053	0.941GlnHis: 0.941 ± 0.028	1.584GlnIle: 1.584 ± 0.04	0.86GlnLys: 0.86 ± 0.028	4.215GlnLeu: 4.215 ± 0.066	0.809GlnMet: 0.809 ± 0.025	0.815GlnAsn: 0.815 ± 0.027	1.947GlnPro: 1.947 ± 0.043	1.862GlnGln: 1.862 ± 0.045	3.752GlnArg: 3.752 ± 0.06	2.236GlnSer: 2.236 ± 0.044	1.744GlnThr: 1.744 ± 0.041	2.671GlnVal: 2.671 ± 0.053	0.566GlnTrp: 0.566 ± 0.022	0.773GlnTyr: 0.773 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.191ArgAla: 7.191 ± 0.089	0.723ArgCys: 0.723 ± 0.028	5.028ArgAsp: 5.028 ± 0.068	5.444ArgGlu: 5.444 ± 0.08	2.977ArgPhe: 2.977 ± 0.055	5.315ArgGly: 5.315 ± 0.07	1.968ArgHis: 1.968 ± 0.04	3.761ArgIle: 3.761 ± 0.051	1.94ArgLys: 1.94 ± 0.049	8.521ArgLeu: 8.521 ± 0.119	1.798ArgMet: 1.798 ± 0.042	2.149ArgAsn: 2.149 ± 0.045	3.078ArgPro: 3.078 ± 0.053	3.382ArgGln: 3.382 ± 0.064	6.132ArgArg: 6.132 ± 0.08	4.282ArgSer: 4.282 ± 0.061	3.036ArgThr: 3.036 ± 0.053	5.404ArgVal: 5.404 ± 0.068	1.184ArgTrp: 1.184 ± 0.033	2.199ArgTyr: 2.199 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.996SerAla: 6.996 ± 0.077	0.535SerCys: 0.535 ± 0.022	3.649SerAsp: 3.649 ± 0.061	3.296SerGlu: 3.296 ± 0.053	1.989SerPhe: 1.989 ± 0.04	5.99SerGly: 5.99 ± 0.087	1.266SerHis: 1.266 ± 0.033	2.707SerIle: 2.707 ± 0.045	1.17SerLys: 1.17 ± 0.037	6.742SerLeu: 6.742 ± 0.074	1.408SerMet: 1.408 ± 0.036	1.492SerAsn: 1.492 ± 0.038	2.96SerPro: 2.96 ± 0.055	1.994SerGln: 1.994 ± 0.047	4.51SerArg: 4.51 ± 0.064	3.372SerSer: 3.372 ± 0.059	2.888SerThr: 2.888 ± 0.048	4.512SerVal: 4.512 ± 0.066	0.855SerTrp: 0.855 ± 0.032	1.426SerTyr: 1.426 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	5.825ThrAla: 5.825 ± 0.081	0.467ThrCys: 0.467 ± 0.022	3.064ThrAsp: 3.064 ± 0.05	2.633ThrGlu: 2.633 ± 0.045	1.803ThrPhe: 1.803 ± 0.04	4.792ThrGly: 4.792 ± 0.065	1.093ThrHis: 1.093 ± 0.031	2.107ThrIle: 2.107 ± 0.044	0.723ThrLys: 0.723 ± 0.026	6.827ThrLeu: 6.827 ± 0.088	0.93ThrMet: 0.93 ± 0.027	1.123ThrAsn: 1.123 ± 0.034	3.094ThrPro: 3.094 ± 0.061	1.663ThrGln: 1.663 ± 0.037	3.757ThrArg: 3.757 ± 0.062	2.708ThrSer: 2.708 ± 0.047	2.594ThrThr: 2.594 ± 0.046	4.116ThrVal: 4.116 ± 0.068	0.686ThrTrp: 0.686 ± 0.028	1.205ThrTyr: 1.205 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	8.288ValAla: 8.288 ± 0.091	0.729ValCys: 0.729 ± 0.024	4.667ValAsp: 4.667 ± 0.064	4.311ValGlu: 4.311 ± 0.081	2.822ValPhe: 2.822 ± 0.057	5.104ValGly: 5.104 ± 0.074	1.437ValHis: 1.437 ± 0.04	3.943ValIle: 3.943 ± 0.065	1.7ValLys: 1.7 ± 0.043	7.513ValLeu: 7.513 ± 0.095	1.731ValMet: 1.731 ± 0.039	2.219ValAsn: 2.219 ± 0.056	3.521ValPro: 3.521 ± 0.064	2.271ValGln: 2.271 ± 0.042	4.709ValArg: 4.709 ± 0.072	4.793ValSer: 4.793 ± 0.063	4.217ValThr: 4.217 ± 0.068	5.628ValVal: 5.628 ± 0.088	0.907ValTrp: 0.907 ± 0.032	1.798ValTyr: 1.798 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.052TrpAla: 1.052 ± 0.032	0.158TrpCys: 0.158 ± 0.013	0.694TrpAsp: 0.694 ± 0.028	0.653TrpGlu: 0.653 ± 0.029	0.537TrpPhe: 0.537 ± 0.019	0.893TrpGly: 0.893 ± 0.027	0.375TrpHis: 0.375 ± 0.018	0.64TrpIle: 0.64 ± 0.025	0.332TrpLys: 0.332 ± 0.017	1.964TrpLeu: 1.964 ± 0.045	0.393TrpMet: 0.393 ± 0.02	0.425TrpAsn: 0.425 ± 0.021	0.619TrpPro: 0.619 ± 0.022	0.856TrpGln: 0.856 ± 0.028	1.333TrpArg: 1.333 ± 0.034	0.877TrpSer: 0.877 ± 0.029	0.699TrpThr: 0.699 ± 0.024	0.931TrpVal: 0.931 ± 0.029	0.229TrpTrp: 0.229 ± 0.015	0.356TrpTyr: 0.356 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.683TyrAla: 2.683 ± 0.053	0.291TyrCys: 0.291 ± 0.014	1.449TyrAsp: 1.449 ± 0.039	1.208TyrGlu: 1.208 ± 0.033	0.956TyrPhe: 0.956 ± 0.029	2.086TyrGly: 2.086 ± 0.041	0.614TyrHis: 0.614 ± 0.021	0.964TyrIle: 0.964 ± 0.027	0.527TyrLys: 0.527 ± 0.025	2.91TyrLeu: 2.91 ± 0.043	0.486TyrMet: 0.486 ± 0.02	0.733TyrAsn: 0.733 ± 0.027	1.322TyrPro: 1.322 ± 0.033	0.997TyrGln: 0.997 ± 0.029	2.545TyrArg: 2.545 ± 0.057	1.492TyrSer: 1.492 ± 0.04	1.306TyrThr: 1.306 ± 0.035	1.565TyrVal: 1.565 ± 0.036	0.39TyrTrp: 0.39 ± 0.02	0.767TyrTyr: 0.767 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3437 proteins (1197166 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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