Amino acid dipepetide frequency for Hubei odonate virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.8AlaAla: 3.8 ± 2.014
1.9AlaCys: 1.9 ± 0.936
4.117AlaAsp: 4.117 ± 1.567
2.217AlaGlu: 2.217 ± 0.318
2.533AlaPhe: 2.533 ± 0.637
3.483AlaGly: 3.483 ± 1.528
0.95AlaHis: 0.95 ± 0.459
5.7AlaIle: 5.7 ± 1.342
2.533AlaLys: 2.533 ± 0.999
3.483AlaLeu: 3.483 ± 0.516
2.85AlaMet: 2.85 ± 0.931
4.117AlaAsn: 4.117 ± 0.47
1.583AlaPro: 1.583 ± 0.443
1.583AlaGln: 1.583 ± 0.365
0.633AlaArg: 0.633 ± 0.313
4.433AlaSer: 4.433 ± 2.072
2.217AlaThr: 2.217 ± 1.384
4.75AlaVal: 4.75 ± 2.071
0.0AlaTrp: 0.0 ± 0.0
0.95AlaTyr: 0.95 ± 0.469
0.0AlaXaa: 0.0 ± 0.0
Cys
1.267CysAla: 1.267 ± 0.942
0.0CysCys: 0.0 ± 0.0
1.9CysAsp: 1.9 ± 0.787
0.633CysGlu: 0.633 ± 0.262
0.95CysPhe: 0.95 ± 0.203
0.95CysGly: 0.95 ± 0.636
0.317CysHis: 0.317 ± 0.156
0.95CysIle: 0.95 ± 0.203
0.633CysLys: 0.633 ± 0.762
2.85CysLeu: 2.85 ± 0.958
0.95CysMet: 0.95 ± 0.469
0.95CysAsn: 0.95 ± 0.469
0.95CysPro: 0.95 ± 0.469
1.267CysGln: 1.267 ± 0.251
1.583CysArg: 1.583 ± 0.895
3.167CysSer: 3.167 ± 1.894
1.9CysThr: 1.9 ± 0.447
1.9CysVal: 1.9 ± 1.271
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.85AspAla: 2.85 ± 0.479
0.95AspCys: 0.95 ± 0.469
5.066AspAsp: 5.066 ± 1.508
1.9AspGlu: 1.9 ± 0.939
3.483AspPhe: 3.483 ± 1.528
2.533AspGly: 2.533 ± 0.637
1.583AspHis: 1.583 ± 0.58
4.117AspIle: 4.117 ± 1.001
5.383AspLys: 5.383 ± 2.487
5.383AspLeu: 5.383 ± 0.148
1.9AspMet: 1.9 ± 0.372
2.85AspAsn: 2.85 ± 1.408
1.583AspPro: 1.583 ± 0.282
2.533AspGln: 2.533 ± 0.799
2.85AspArg: 2.85 ± 0.951
4.117AspSer: 4.117 ± 0.229
3.167AspThr: 3.167 ± 0.188
5.383AspVal: 5.383 ± 0.812
0.633AspTrp: 0.633 ± 0.313
4.433AspTyr: 4.433 ± 0.808
0.0AspXaa: 0.0 ± 0.0
Glu
2.85GluAla: 2.85 ± 0.479
1.9GluCys: 1.9 ± 0.407
3.8GluAsp: 3.8 ± 1.413
1.267GluGlu: 1.267 ± 0.759
1.267GluPhe: 1.267 ± 0.525
2.533GluGly: 2.533 ± 1.272
2.217GluHis: 2.217 ± 0.649
3.483GluIle: 3.483 ± 0.812
3.483GluLys: 3.483 ± 0.812
7.6GluLeu: 7.6 ± 1.504
1.9GluMet: 1.9 ± 0.256
2.85GluAsn: 2.85 ± 0.951
1.9GluPro: 1.9 ± 0.447
1.267GluGln: 1.267 ± 0.251
0.95GluArg: 0.95 ± 0.203
2.533GluSer: 2.533 ± 0.716
2.533GluThr: 2.533 ± 0.716
3.8GluVal: 3.8 ± 0.497
0.0GluTrp: 0.0 ± 0.0
2.217GluTyr: 2.217 ± 0.318
0.0GluXaa: 0.0 ± 0.0
Phe
1.583PheAla: 1.583 ± 1.145
0.317PheCys: 0.317 ± 0.156
2.85PheAsp: 2.85 ± 0.647
3.167PheGlu: 3.167 ± 0.623
0.317PhePhe: 0.317 ± 0.381
2.533PheGly: 2.533 ± 0.501
0.317PheHis: 0.317 ± 0.156
2.85PheIle: 2.85 ± 0.606
3.483PheLys: 3.483 ± 0.341
4.433PheLeu: 4.433 ± 0.362
0.95PheMet: 0.95 ± 0.469
3.8PheAsn: 3.8 ± 0.584
1.267PhePro: 1.267 ± 1.287
1.267PheGln: 1.267 ± 0.759
2.217PheArg: 2.217 ± 0.293
2.533PheSer: 2.533 ± 0.754
0.95PheThr: 0.95 ± 0.203
2.217PheVal: 2.217 ± 0.876
0.317PheTrp: 0.317 ± 0.156
0.317PheTyr: 0.317 ± 0.381
0.0PheXaa: 0.0 ± 0.0
Gly
3.8GlyAla: 3.8 ± 1.498
2.217GlyCys: 2.217 ± 1.155
2.533GlyAsp: 2.533 ± 0.501
2.533GlyGlu: 2.533 ± 0.716
0.95GlyPhe: 0.95 ± 0.636
1.9GlyGly: 1.9 ± 1.007
1.9GlyHis: 1.9 ± 0.812
2.533GlyIle: 2.533 ± 1.05
4.75GlyLys: 4.75 ± 0.846
4.117GlyLeu: 4.117 ± 0.229
2.533GlyMet: 2.533 ± 0.637
1.9GlyAsn: 1.9 ± 0.256
1.267GlyPro: 1.267 ± 0.377
1.267GlyGln: 1.267 ± 1.015
1.583GlyArg: 1.583 ± 0.443
2.85GlySer: 2.85 ± 0.951
3.483GlyThr: 3.483 ± 0.516
3.8GlyVal: 3.8 ± 0.511
0.633GlyTrp: 0.633 ± 0.262
1.9GlyTyr: 1.9 ± 0.787
0.0GlyXaa: 0.0 ± 0.0
His
1.267HisAla: 1.267 ± 0.377
0.0HisCys: 0.0 ± 0.0
3.167HisAsp: 3.167 ± 0.188
0.95HisGlu: 0.95 ± 0.636
0.95HisPhe: 0.95 ± 0.504
0.95HisGly: 0.95 ± 0.504
0.633HisHis: 0.633 ± 0.313
0.633HisIle: 0.633 ± 0.262
1.9HisLys: 1.9 ± 0.256
3.483HisLeu: 3.483 ± 1.258
0.95HisMet: 0.95 ± 0.469
0.317HisAsn: 0.317 ± 0.156
0.633HisPro: 0.633 ± 0.262
1.583HisGln: 1.583 ± 0.365
1.267HisArg: 1.267 ± 0.499
3.167HisSer: 3.167 ± 0.749
1.583HisThr: 1.583 ± 0.58
0.0HisVal: 0.0 ± 0.0
0.317HisTrp: 0.317 ± 0.381
1.583HisTyr: 1.583 ± 0.782
0.0HisXaa: 0.0 ± 0.0
Ile
5.383IleAla: 5.383 ± 1.905
1.267IleCys: 1.267 ± 0.377
5.066IleAsp: 5.066 ± 1.002
5.383IleGlu: 5.383 ± 0.477
1.583IlePhe: 1.583 ± 0.443
4.433IleGly: 4.433 ± 0.32
1.583IleHis: 1.583 ± 0.365
5.383IleIle: 5.383 ± 0.995
5.383IleLys: 5.383 ± 1.277
5.7IleLeu: 5.7 ± 0.559
0.95IleMet: 0.95 ± 0.203
6.016IleAsn: 6.016 ± 1.59
2.533IlePro: 2.533 ± 0.501
1.9IleGln: 1.9 ± 0.256
2.533IleArg: 2.533 ± 0.629
6.966IleSer: 6.966 ± 0.221
3.483IleThr: 3.483 ± 0.715
4.433IleVal: 4.433 ± 1.965
0.0IleTrp: 0.0 ± 0.0
3.167IleTyr: 3.167 ± 0.73
0.0IleXaa: 0.0 ± 0.0
Lys
4.75LysAla: 4.75 ± 0.972
1.267LysCys: 1.267 ± 1.015
4.433LysAsp: 4.433 ± 0.967
5.383LysGlu: 5.383 ± 2.065
2.85LysPhe: 2.85 ± 0.647
1.267LysGly: 1.267 ± 0.251
2.533LysHis: 2.533 ± 0.501
4.117LysIle: 4.117 ± 0.965
4.117LysLys: 4.117 ± 0.556
6.016LysLeu: 6.016 ± 0.579
3.167LysMet: 3.167 ± 1.56
3.483LysAsn: 3.483 ± 0.812
2.217LysPro: 2.217 ± 0.947
3.483LysGln: 3.483 ± 1.169
1.583LysArg: 1.583 ± 0.443
4.75LysSer: 4.75 ± 0.846
5.7LysThr: 5.7 ± 1.902
4.433LysVal: 4.433 ± 0.32
0.633LysTrp: 0.633 ± 0.313
5.383LysTyr: 5.383 ± 0.481
0.0LysXaa: 0.0 ± 0.0
Leu
5.383LeuAla: 5.383 ± 0.594
1.583LeuCys: 1.583 ± 0.365
6.333LeuAsp: 6.333 ± 0.669
4.75LeuGlu: 4.75 ± 0.846
2.85LeuPhe: 2.85 ± 0.057
3.483LeuGly: 3.483 ± 0.672
0.95LeuHis: 0.95 ± 0.203
8.233LeuIle: 8.233 ± 1.555
6.65LeuLys: 6.65 ± 2.081
9.183LeuLeu: 9.183 ± 1.453
2.533LeuMet: 2.533 ± 1.05
4.75LeuAsn: 4.75 ± 1.017
3.483LeuPro: 3.483 ± 0.341
1.267LeuGln: 1.267 ± 0.251
3.483LeuArg: 3.483 ± 0.341
7.283LeuSer: 7.283 ± 1.868
6.65LeuThr: 6.65 ± 0.109
6.016LeuVal: 6.016 ± 1.169
0.95LeuTrp: 0.95 ± 0.203
4.433LeuTyr: 4.433 ± 0.362
0.0LeuXaa: 0.0 ± 0.0
Met
1.583MetAla: 1.583 ± 0.443
0.317MetCys: 0.317 ± 0.156
0.95MetAsp: 0.95 ± 0.203
0.95MetGlu: 0.95 ± 0.504
0.633MetPhe: 0.633 ± 0.313
0.633MetGly: 0.633 ± 0.313
0.95MetHis: 0.95 ± 0.459
3.483MetIle: 3.483 ± 0.715
3.167MetLys: 3.167 ± 0.73
4.117MetLeu: 4.117 ± 1.001
1.267MetMet: 1.267 ± 0.31
1.9MetAsn: 1.9 ± 1.615
0.633MetPro: 0.633 ± 0.313
1.583MetGln: 1.583 ± 0.443
0.95MetArg: 0.95 ± 0.203
3.167MetSer: 3.167 ± 0.564
1.9MetThr: 1.9 ± 0.407
2.85MetVal: 2.85 ± 0.61
0.0MetTrp: 0.0 ± 0.0
0.95MetTyr: 0.95 ± 1.144
0.0MetXaa: 0.0 ± 0.0
Asn
1.583AsnAla: 1.583 ± 0.58
0.633AsnCys: 0.633 ± 0.262
2.85AsnAsp: 2.85 ± 1.084
2.217AsnGlu: 2.217 ± 0.429
3.167AsnPhe: 3.167 ± 0.623
3.483AsnGly: 3.483 ± 0.672
0.95AsnHis: 0.95 ± 0.469
6.016AsnIle: 6.016 ± 1.59
5.066AsnLys: 5.066 ± 1.121
5.383AsnLeu: 5.383 ± 0.477
1.583AsnMet: 1.583 ± 0.365
3.483AsnAsn: 3.483 ± 0.836
3.8AsnPro: 3.8 ± 0.513
1.583AsnGln: 1.583 ± 0.282
3.483AsnArg: 3.483 ± 0.715
3.8AsnSer: 3.8 ± 0.497
1.9AsnThr: 1.9 ± 0.503
3.483AsnVal: 3.483 ± 0.341
0.95AsnTrp: 0.95 ± 0.469
3.8AsnTyr: 3.8 ± 1.413
0.0AsnXaa: 0.0 ± 0.0
Pro
2.533ProAla: 2.533 ± 1.518
0.0ProCys: 0.0 ± 0.0
2.217ProAsp: 2.217 ± 0.318
2.533ProGlu: 2.533 ± 1.251
2.217ProPhe: 2.217 ± 0.649
1.583ProGly: 1.583 ± 2.144
0.633ProHis: 0.633 ± 0.471
3.167ProIle: 3.167 ± 0.785
2.217ProLys: 2.217 ± 0.649
1.267ProLeu: 1.267 ± 0.499
1.267ProMet: 1.267 ± 0.525
1.9ProAsn: 1.9 ± 0.939
0.95ProPro: 0.95 ± 0.636
0.95ProGln: 0.95 ± 0.203
2.217ProArg: 2.217 ± 1.813
4.433ProSer: 4.433 ± 0.386
2.85ProThr: 2.85 ± 0.564
2.217ProVal: 2.217 ± 0.699
0.0ProTrp: 0.0 ± 0.0
1.267ProTyr: 1.267 ± 0.525
0.0ProXaa: 0.0 ± 0.0
Gln
2.217GlnAla: 2.217 ± 0.318
1.267GlnCys: 1.267 ± 0.626
0.95GlnAsp: 0.95 ± 0.636
0.633GlnGlu: 0.633 ± 0.471
2.217GlnPhe: 2.217 ± 0.749
1.583GlnGly: 1.583 ± 0.782
0.95GlnHis: 0.95 ± 0.636
2.533GlnIle: 2.533 ± 0.629
0.633GlnLys: 0.633 ± 0.313
4.117GlnLeu: 4.117 ± 1.496
0.633GlnMet: 0.633 ± 0.313
1.267GlnAsn: 1.267 ± 0.251
0.95GlnPro: 0.95 ± 0.469
1.267GlnGln: 1.267 ± 0.251
1.583GlnArg: 1.583 ± 0.443
2.533GlnSer: 2.533 ± 0.637
1.267GlnThr: 1.267 ± 0.377
0.95GlnVal: 0.95 ± 0.203
0.633GlnTrp: 0.633 ± 0.313
2.533GlnTyr: 2.533 ± 0.754
0.0GlnXaa: 0.0 ± 0.0
Arg
1.267ArgAla: 1.267 ± 0.251
1.267ArgCys: 1.267 ± 0.251
3.167ArgAsp: 3.167 ± 0.334
1.9ArgGlu: 1.9 ± 0.447
1.9ArgPhe: 1.9 ± 1.413
4.117ArgGly: 4.117 ± 0.853
2.217ArgHis: 2.217 ± 0.318
3.483ArgIle: 3.483 ± 0.864
2.533ArgLys: 2.533 ± 0.637
3.167ArgLeu: 3.167 ± 0.73
1.9ArgMet: 1.9 ± 0.936
2.533ArgAsn: 2.533 ± 0.944
2.533ArgPro: 2.533 ± 1.53
0.633ArgGln: 0.633 ± 0.471
2.85ArgArg: 2.85 ± 1.416
3.8ArgSer: 3.8 ± 0.497
1.267ArgThr: 1.267 ± 0.525
1.9ArgVal: 1.9 ± 0.407
0.317ArgTrp: 0.317 ± 0.381
3.483ArgTyr: 3.483 ± 0.836
0.0ArgXaa: 0.0 ± 0.0
Ser
2.533SerAla: 2.533 ± 1.377
1.9SerCys: 1.9 ± 0.787
4.117SerAsp: 4.117 ± 1.15
3.8SerGlu: 3.8 ± 1.005
2.85SerPhe: 2.85 ± 0.564
2.85SerGly: 2.85 ± 0.057
2.533SerHis: 2.533 ± 0.43
6.333SerIle: 6.333 ± 1.032
5.7SerLys: 5.7 ± 1.261
6.333SerLeu: 6.333 ± 1.804
2.533SerMet: 2.533 ± 0.501
4.75SerAsn: 4.75 ± 0.508
1.9SerPro: 1.9 ± 0.787
1.9SerGln: 1.9 ± 0.688
6.016SerArg: 6.016 ± 0.23
8.866SerSer: 8.866 ± 2.443
6.65SerThr: 6.65 ± 0.762
4.75SerVal: 4.75 ± 0.904
0.633SerTrp: 0.633 ± 0.262
3.8SerTyr: 3.8 ± 0.814
0.0SerXaa: 0.0 ± 0.0
Thr
2.85ThrAla: 2.85 ± 0.564
1.583ThrCys: 1.583 ± 1.395
2.217ThrAsp: 2.217 ± 0.811
3.483ThrGlu: 3.483 ± 0.864
2.533ThrPhe: 2.533 ± 0.141
2.85ThrGly: 2.85 ± 1.869
0.95ThrHis: 0.95 ± 0.203
3.483ThrIle: 3.483 ± 1.093
3.167ThrLys: 3.167 ± 0.564
5.383ThrLeu: 5.383 ± 0.995
1.583ThrMet: 1.583 ± 0.365
4.117ThrAsn: 4.117 ± 1.15
2.533ThrPro: 2.533 ± 0.716
2.217ThrGln: 2.217 ± 0.649
3.167ThrArg: 3.167 ± 0.73
4.117ThrSer: 4.117 ± 0.853
3.167ThrThr: 3.167 ± 1.564
3.167ThrVal: 3.167 ± 0.623
0.633ThrTrp: 0.633 ± 0.762
3.483ThrTyr: 3.483 ± 1.263
0.0ThrXaa: 0.0 ± 0.0
Val
3.483ValAla: 3.483 ± 0.715
2.533ValCys: 2.533 ± 1.518
3.8ValAsp: 3.8 ± 0.752
3.8ValGlu: 3.8 ± 0.153
3.167ValPhe: 3.167 ± 0.785
2.85ValGly: 2.85 ± 0.999
2.217ValHis: 2.217 ± 0.699
2.85ValIle: 2.85 ± 0.057
6.016ValLys: 6.016 ± 2.12
4.433ValLeu: 4.433 ± 1.036
0.317ValMet: 0.317 ± 0.381
5.7ValAsn: 5.7 ± 1.1
2.533ValPro: 2.533 ± 0.716
0.95ValGln: 0.95 ± 0.504
4.75ValArg: 4.75 ± 1.241
3.8ValSer: 3.8 ± 0.497
2.533ValThr: 2.533 ± 1.05
4.75ValVal: 4.75 ± 1.017
0.633ValTrp: 0.633 ± 0.313
2.85ValTyr: 2.85 ± 0.057
0.0ValXaa: 0.0 ± 0.0
Trp
0.633TrpAla: 0.633 ± 0.762
0.633TrpCys: 0.633 ± 0.262
0.633TrpAsp: 0.633 ± 0.313
0.0TrpGlu: 0.0 ± 0.0
0.317TrpPhe: 0.317 ± 0.381
0.633TrpGly: 0.633 ± 0.313
0.0TrpHis: 0.0 ± 0.0
0.633TrpIle: 0.633 ± 0.313
0.0TrpLys: 0.0 ± 0.0
0.633TrpLeu: 0.633 ± 0.262
0.317TrpMet: 0.317 ± 0.156
0.633TrpAsn: 0.633 ± 0.313
0.633TrpPro: 0.633 ± 0.313
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.633TrpSer: 0.633 ± 0.313
0.0TrpThr: 0.0 ± 0.0
0.317TrpVal: 0.317 ± 0.156
0.0TrpTrp: 0.0 ± 0.0
0.95TrpTyr: 0.95 ± 0.636
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.217TyrAla: 2.217 ± 0.293
1.583TyrCys: 1.583 ± 0.443
2.85TyrAsp: 2.85 ± 0.716
2.85TyrGlu: 2.85 ± 0.057
0.95TyrPhe: 0.95 ± 0.469
3.8TyrGly: 3.8 ± 1.005
0.95TyrHis: 0.95 ± 0.459
3.167TyrIle: 3.167 ± 1.104
4.75TyrLys: 4.75 ± 1.013
3.167TyrLeu: 3.167 ± 0.886
1.583TyrMet: 1.583 ± 0.282
1.9TyrAsn: 1.9 ± 0.939
2.533TyrPro: 2.533 ± 1.05
2.217TyrGln: 2.217 ± 0.811
2.533TyrArg: 2.533 ± 0.501
3.8TyrSer: 3.8 ± 1.005
3.483TyrThr: 3.483 ± 0.672
2.85TyrVal: 2.85 ± 1.416
0.317TyrTrp: 0.317 ± 0.156
2.533TyrTyr: 2.533 ± 0.501
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3159 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski