Amino acid dipepetide frequency for Shimia gijangensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.856AlaAla: 12.856 ± 0.125	1.059AlaCys: 1.059 ± 0.035	6.33AlaAsp: 6.33 ± 0.086	7.216AlaGlu: 7.216 ± 0.1	4.14AlaPhe: 4.14 ± 0.062	9.079AlaGly: 9.079 ± 0.115	2.211AlaHis: 2.211 ± 0.044	5.814AlaIle: 5.814 ± 0.069	4.317AlaLys: 4.317 ± 0.065	11.828AlaLeu: 11.828 ± 0.107	3.62AlaMet: 3.62 ± 0.058	3.098AlaAsn: 3.098 ± 0.058	4.738AlaPro: 4.738 ± 0.072	3.947AlaGln: 3.947 ± 0.06	6.957AlaArg: 6.957 ± 0.089	5.734AlaSer: 5.734 ± 0.074	5.644AlaThr: 5.644 ± 0.082	7.524AlaVal: 7.524 ± 0.08	1.227AlaTrp: 1.227 ± 0.032	2.509AlaTyr: 2.509 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.035CysAla: 1.035 ± 0.029	0.129CysCys: 0.129 ± 0.01	0.67CysAsp: 0.67 ± 0.024	0.515CysGlu: 0.515 ± 0.021	0.38CysPhe: 0.38 ± 0.018	0.987CysGly: 0.987 ± 0.032	0.292CysHis: 0.292 ± 0.016	0.454CysIle: 0.454 ± 0.023	0.296CysLys: 0.296 ± 0.015	0.92CysLeu: 0.92 ± 0.029	0.22CysMet: 0.22 ± 0.012	0.29CysAsn: 0.29 ± 0.013	0.514CysPro: 0.514 ± 0.02	0.299CysGln: 0.299 ± 0.015	0.55CysArg: 0.55 ± 0.024	0.54CysSer: 0.54 ± 0.025	0.479CysThr: 0.479 ± 0.021	0.67CysVal: 0.67 ± 0.022	0.12CysTrp: 0.12 ± 0.011	0.249CysTyr: 0.249 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.769AspAla: 6.769 ± 0.09	0.565AspCys: 0.565 ± 0.023	3.549AspAsp: 3.549 ± 0.087	3.709AspGlu: 3.709 ± 0.054	2.334AspPhe: 2.334 ± 0.048	5.451AspGly: 5.451 ± 0.106	1.414AspHis: 1.414 ± 0.036	3.373AspIle: 3.373 ± 0.065	2.165AspLys: 2.165 ± 0.048	6.429AspLeu: 6.429 ± 0.072	1.886AspMet: 1.886 ± 0.036	1.611AspAsn: 1.611 ± 0.042	3.326AspPro: 3.326 ± 0.052	2.176AspGln: 2.176 ± 0.043	3.74AspArg: 3.74 ± 0.062	2.392AspSer: 2.392 ± 0.054	3.16AspThr: 3.16 ± 0.063	4.746AspVal: 4.746 ± 0.073	1.138AspTrp: 1.138 ± 0.033	1.598AspTyr: 1.598 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.392GluAla: 7.392 ± 0.098	0.434GluCys: 0.434 ± 0.019	3.589GluAsp: 3.589 ± 0.057	3.553GluGlu: 3.553 ± 0.073	2.108GluPhe: 2.108 ± 0.047	4.727GluGly: 4.727 ± 0.063	1.215GluHis: 1.215 ± 0.031	3.902GluIle: 3.902 ± 0.059	2.609GluLys: 2.609 ± 0.049	5.191GluLeu: 5.191 ± 0.074	2.038GluMet: 2.038 ± 0.046	2.167GluAsn: 2.167 ± 0.041	2.367GluPro: 2.367 ± 0.05	2.119GluGln: 2.119 ± 0.049	3.89GluArg: 3.89 ± 0.063	2.411GluSer: 2.411 ± 0.043	3.907GluThr: 3.907 ± 0.059	4.337GluVal: 4.337 ± 0.063	0.745GluTrp: 0.745 ± 0.025	1.21GluTyr: 1.21 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.229PheAla: 4.229 ± 0.057	0.545PheCys: 0.545 ± 0.021	2.995PheAsp: 2.995 ± 0.054	2.519PheGlu: 2.519 ± 0.048	1.617PhePhe: 1.617 ± 0.042	3.89PheGly: 3.89 ± 0.063	0.828PheHis: 0.828 ± 0.028	1.679PheIle: 1.679 ± 0.039	1.138PheLys: 1.138 ± 0.033	3.674PheLeu: 3.674 ± 0.062	0.929PheMet: 0.929 ± 0.029	1.146PheAsn: 1.146 ± 0.033	1.605PhePro: 1.605 ± 0.034	1.187PheGln: 1.187 ± 0.028	2.126PheArg: 2.126 ± 0.042	2.527PheSer: 2.527 ± 0.052	2.162PheThr: 2.162 ± 0.047	2.897PheVal: 2.897 ± 0.051	0.609PheTrp: 0.609 ± 0.023	1.0PheTyr: 1.0 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	8.692GlyAla: 8.692 ± 0.098	0.88GlyCys: 0.88 ± 0.031	4.896GlyAsp: 4.896 ± 0.088	4.615GlyGlu: 4.615 ± 0.067	3.863GlyPhe: 3.863 ± 0.058	7.152GlyGly: 7.152 ± 0.148	1.982GlyHis: 1.982 ± 0.041	4.545GlyIle: 4.545 ± 0.068	3.691GlyLys: 3.691 ± 0.061	8.708GlyLeu: 8.708 ± 0.093	2.683GlyMet: 2.683 ± 0.053	2.462GlyAsn: 2.462 ± 0.063	3.289GlyPro: 3.289 ± 0.056	3.183GlyGln: 3.183 ± 0.054	4.928GlyArg: 4.928 ± 0.072	4.431GlySer: 4.431 ± 0.089	4.499GlyThr: 4.499 ± 0.084	6.478GlyVal: 6.478 ± 0.08	1.462GlyTrp: 1.462 ± 0.036	2.441GlyTyr: 2.441 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.192HisAla: 2.192 ± 0.042	0.26HisCys: 0.26 ± 0.015	1.29HisAsp: 1.29 ± 0.032	1.195HisGlu: 1.195 ± 0.032	0.911HisPhe: 0.911 ± 0.026	1.866HisGly: 1.866 ± 0.038	0.601HisHis: 0.601 ± 0.023	1.046HisIle: 1.046 ± 0.031	0.689HisLys: 0.689 ± 0.025	2.183HisLeu: 2.183 ± 0.044	0.659HisMet: 0.659 ± 0.026	0.574HisAsn: 0.574 ± 0.02	1.36HisPro: 1.36 ± 0.034	0.688HisGln: 0.688 ± 0.023	1.25HisArg: 1.25 ± 0.033	1.108HisSer: 1.108 ± 0.032	0.974HisThr: 0.974 ± 0.028	1.601HisVal: 1.601 ± 0.037	0.393HisTrp: 0.393 ± 0.02	0.604HisTyr: 0.604 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.585IleAla: 6.585 ± 0.077	0.65IleCys: 0.65 ± 0.023	3.663IleAsp: 3.663 ± 0.067	3.751IleGlu: 3.751 ± 0.064	1.819IlePhe: 1.819 ± 0.04	5.047IleGly: 5.047 ± 0.073	1.009IleHis: 1.009 ± 0.026	2.425IleIle: 2.425 ± 0.054	1.766IleLys: 1.766 ± 0.047	5.002IleLeu: 5.002 ± 0.068	1.181IleMet: 1.181 ± 0.035	1.543IleAsn: 1.543 ± 0.04	2.413IlePro: 2.413 ± 0.046	1.379IleGln: 1.379 ± 0.034	3.089IleArg: 3.089 ± 0.056	3.462IleSer: 3.462 ± 0.058	2.957IleThr: 2.957 ± 0.056	4.028IleVal: 4.028 ± 0.061	0.777IleTrp: 0.777 ± 0.029	1.278IleTyr: 1.278 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	4.325LysAla: 4.325 ± 0.071	0.274LysCys: 0.274 ± 0.015	2.303LysAsp: 2.303 ± 0.045	2.055LysGlu: 2.055 ± 0.043	1.2LysPhe: 1.2 ± 0.034	3.295LysGly: 3.295 ± 0.058	0.806LysHis: 0.806 ± 0.025	2.177LysIle: 2.177 ± 0.043	1.687LysLys: 1.687 ± 0.043	3.494LysLeu: 3.494 ± 0.054	1.106LysMet: 1.106 ± 0.029	1.175LysAsn: 1.175 ± 0.03	2.048LysPro: 2.048 ± 0.048	1.249LysGln: 1.249 ± 0.032	2.524LysArg: 2.524 ± 0.05	2.313LysSer: 2.313 ± 0.048	2.409LysThr: 2.409 ± 0.044	2.736LysVal: 2.736 ± 0.048	0.517LysTrp: 0.517 ± 0.022	0.854LysTyr: 0.854 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	11.047LeuAla: 11.047 ± 0.107	0.96LeuCys: 0.96 ± 0.029	5.758LeuAsp: 5.758 ± 0.062	5.568LeuGlu: 5.568 ± 0.075	3.683LeuPhe: 3.683 ± 0.057	8.118LeuGly: 8.118 ± 0.083	1.845LeuHis: 1.845 ± 0.042	5.257LeuIle: 5.257 ± 0.072	3.98LeuLys: 3.98 ± 0.068	8.285LeuLeu: 8.285 ± 0.112	2.783LeuMet: 2.783 ± 0.05	3.143LeuAsn: 3.143 ± 0.041	5.008LeuPro: 5.008 ± 0.075	2.956LeuGln: 2.956 ± 0.054	6.155LeuArg: 6.155 ± 0.084	6.763LeuSer: 6.763 ± 0.073	5.871LeuThr: 5.871 ± 0.078	6.767LeuVal: 6.767 ± 0.08	1.268LeuTrp: 1.268 ± 0.041	1.918LeuTyr: 1.918 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	3.429MetAla: 3.429 ± 0.058	0.233MetCys: 0.233 ± 0.014	1.601MetAsp: 1.601 ± 0.033	1.365MetGlu: 1.365 ± 0.036	0.972MetPhe: 0.972 ± 0.029	2.425MetGly: 2.425 ± 0.054	0.552MetHis: 0.552 ± 0.021	1.657MetIle: 1.657 ± 0.045	1.298MetLys: 1.298 ± 0.034	2.641MetLeu: 2.641 ± 0.056	0.882MetMet: 0.882 ± 0.029	0.96MetAsn: 0.96 ± 0.029	1.561MetPro: 1.561 ± 0.042	1.111MetGln: 1.111 ± 0.03	1.963MetArg: 1.963 ± 0.046	1.984MetSer: 1.984 ± 0.047	2.1MetThr: 2.1 ± 0.041	1.989MetVal: 1.989 ± 0.037	0.272MetTrp: 0.272 ± 0.015	0.412MetTyr: 0.412 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.484AsnAla: 3.484 ± 0.05	0.311AsnCys: 0.311 ± 0.016	1.798AsnAsp: 1.798 ± 0.06	1.524AsnGlu: 1.524 ± 0.037	1.142AsnPhe: 1.142 ± 0.029	2.769AsnGly: 2.769 ± 0.064	0.613AsnHis: 0.613 ± 0.021	1.612AsnIle: 1.612 ± 0.039	0.981AsnLys: 0.981 ± 0.026	2.958AsnLeu: 2.958 ± 0.044	0.817AsnMet: 0.817 ± 0.028	0.904AsnAsn: 0.904 ± 0.03	1.982AsnPro: 1.982 ± 0.037	0.895AsnGln: 0.895 ± 0.025	1.887AsnArg: 1.887 ± 0.039	1.554AsnSer: 1.554 ± 0.043	1.655AsnThr: 1.655 ± 0.042	2.225AsnVal: 2.225 ± 0.053	0.59AsnTrp: 0.59 ± 0.024	0.727AsnTyr: 0.727 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	4.488ProAla: 4.488 ± 0.068	0.372ProCys: 0.372 ± 0.017	3.638ProAsp: 3.638 ± 0.056	4.01ProGlu: 4.01 ± 0.068	2.0ProPhe: 2.0 ± 0.037	3.758ProGly: 3.758 ± 0.054	1.07ProHis: 1.07 ± 0.031	2.334ProIle: 2.334 ± 0.046	1.999ProLys: 1.999 ± 0.044	4.249ProLeu: 4.249 ± 0.066	1.405ProMet: 1.405 ± 0.033	1.579ProAsn: 1.579 ± 0.037	1.866ProPro: 1.866 ± 0.043	1.545ProGln: 1.545 ± 0.038	2.341ProArg: 2.341 ± 0.047	2.649ProSer: 2.649 ± 0.047	2.412ProThr: 2.412 ± 0.046	4.015ProVal: 4.015 ± 0.067	0.62ProTrp: 0.62 ± 0.023	1.142ProTyr: 1.142 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.883GlnAla: 3.883 ± 0.063	0.283GlnCys: 0.283 ± 0.018	1.908GlnAsp: 1.908 ± 0.038	1.774GlnGlu: 1.774 ± 0.037	1.233GlnPhe: 1.233 ± 0.033	2.669GlnGly: 2.669 ± 0.05	0.685GlnHis: 0.685 ± 0.026	2.076GlnIle: 2.076 ± 0.041	1.381GlnLys: 1.381 ± 0.034	2.803GlnLeu: 2.803 ± 0.048	1.162GlnMet: 1.162 ± 0.031	1.116GlnAsn: 1.116 ± 0.029	1.494GlnPro: 1.494 ± 0.035	1.093GlnGln: 1.093 ± 0.034	2.06GlnArg: 2.06 ± 0.048	2.154GlnSer: 2.154 ± 0.047	1.875GlnThr: 1.875 ± 0.042	2.473GlnVal: 2.473 ± 0.047	0.423GlnTrp: 0.423 ± 0.019	0.681GlnTyr: 0.681 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	6.282ArgAla: 6.282 ± 0.078	0.486ArgCys: 0.486 ± 0.021	3.87ArgAsp: 3.87 ± 0.061	3.64ArgGlu: 3.64 ± 0.064	2.572ArgPhe: 2.572 ± 0.051	4.005ArgGly: 4.005 ± 0.066	1.428ArgHis: 1.428 ± 0.033	3.505ArgIle: 3.505 ± 0.053	2.657ArgLys: 2.657 ± 0.051	6.331ArgLeu: 6.331 ± 0.087	1.831ArgMet: 1.831 ± 0.041	1.953ArgAsn: 1.953 ± 0.044	2.841ArgPro: 2.841 ± 0.05	2.159ArgGln: 2.159 ± 0.051	4.189ArgArg: 4.189 ± 0.075	3.243ArgSer: 3.243 ± 0.059	2.898ArgThr: 2.898 ± 0.052	4.27ArgVal: 4.27 ± 0.065	0.893ArgTrp: 0.893 ± 0.029	1.514ArgTyr: 1.514 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.742SerAla: 5.742 ± 0.079	0.499SerCys: 0.499 ± 0.02	3.686SerAsp: 3.686 ± 0.06	3.302SerGlu: 3.302 ± 0.052	2.489SerPhe: 2.489 ± 0.046	5.691SerGly: 5.691 ± 0.09	1.297SerHis: 1.297 ± 0.033	2.887SerIle: 2.887 ± 0.051	2.091SerLys: 2.091 ± 0.038	5.355SerLeu: 5.355 ± 0.076	1.595SerMet: 1.595 ± 0.038	1.715SerAsn: 1.715 ± 0.039	2.697SerPro: 2.697 ± 0.043	1.887SerGln: 1.887 ± 0.04	3.133SerArg: 3.133 ± 0.059	2.976SerSer: 2.976 ± 0.067	2.907SerThr: 2.907 ± 0.059	4.183SerVal: 4.183 ± 0.066	0.721SerTrp: 0.721 ± 0.025	1.438SerTyr: 1.438 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.603ThrAla: 5.603 ± 0.081	0.547ThrCys: 0.547 ± 0.023	3.252ThrAsp: 3.252 ± 0.069	3.042ThrGlu: 3.042 ± 0.056	2.149ThrPhe: 2.149 ± 0.04	5.241ThrGly: 5.241 ± 0.086	1.252ThrHis: 1.252 ± 0.031	2.971ThrIle: 2.971 ± 0.063	1.938ThrLys: 1.938 ± 0.038	5.801ThrLeu: 5.801 ± 0.067	1.459ThrMet: 1.459 ± 0.036	1.517ThrAsn: 1.517 ± 0.036	3.334ThrPro: 3.334 ± 0.062	1.698ThrGln: 1.698 ± 0.041	3.262ThrArg: 3.262 ± 0.056	3.173ThrSer: 3.173 ± 0.058	3.065ThrThr: 3.065 ± 0.072	4.187ThrVal: 4.187 ± 0.08	0.661ThrTrp: 0.661 ± 0.026	1.381ThrTyr: 1.381 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	8.09ValAla: 8.09 ± 0.095	0.715ValCys: 0.715 ± 0.026	4.276ValAsp: 4.276 ± 0.07	4.473ValGlu: 4.473 ± 0.061	3.101ValPhe: 3.101 ± 0.056	5.511ValGly: 5.511 ± 0.084	1.401ValHis: 1.401 ± 0.037	4.318ValIle: 4.318 ± 0.064	2.594ValLys: 2.594 ± 0.052	7.343ValLeu: 7.343 ± 0.084	2.207ValMet: 2.207 ± 0.045	2.263ValAsn: 2.263 ± 0.043	3.351ValPro: 3.351 ± 0.055	2.266ValGln: 2.266 ± 0.042	3.974ValArg: 3.974 ± 0.052	4.719ValSer: 4.719 ± 0.073	4.63ValThr: 4.63 ± 0.083	5.785ValVal: 5.785 ± 0.086	1.016ValTrp: 1.016 ± 0.029	1.525ValTyr: 1.525 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.321TrpAla: 1.321 ± 0.033	0.152TrpCys: 0.152 ± 0.011	0.782TrpAsp: 0.782 ± 0.027	0.702TrpGlu: 0.702 ± 0.027	0.597TrpPhe: 0.597 ± 0.021	1.044TrpGly: 1.044 ± 0.033	0.373TrpHis: 0.373 ± 0.018	0.759TrpIle: 0.759 ± 0.024	0.543TrpLys: 0.543 ± 0.021	1.534TrpLeu: 1.534 ± 0.04	0.443TrpMet: 0.443 ± 0.017	0.5TrpAsn: 0.5 ± 0.022	0.638TrpPro: 0.638 ± 0.024	0.618TrpGln: 0.618 ± 0.024	1.026TrpArg: 1.026 ± 0.032	0.813TrpSer: 0.813 ± 0.028	0.728TrpThr: 0.728 ± 0.024	0.978TrpVal: 0.978 ± 0.029	0.219TrpTrp: 0.219 ± 0.014	0.291TrpTyr: 0.291 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.403TyrAla: 2.403 ± 0.04	0.257TyrCys: 0.257 ± 0.013	1.679TyrAsp: 1.679 ± 0.04	1.383TyrGlu: 1.383 ± 0.036	0.994TyrPhe: 0.994 ± 0.032	2.153TyrGly: 2.153 ± 0.042	0.572TyrHis: 0.572 ± 0.025	1.032TyrIle: 1.032 ± 0.035	0.724TyrLys: 0.724 ± 0.025	2.408TyrLeu: 2.408 ± 0.039	0.503TyrMet: 0.503 ± 0.023	0.711TyrAsn: 0.711 ± 0.025	1.06TyrPro: 1.06 ± 0.032	0.768TyrGln: 0.768 ± 0.023	1.523TyrArg: 1.523 ± 0.037	1.346TyrSer: 1.346 ± 0.036	1.199TyrThr: 1.199 ± 0.036	1.666TyrVal: 1.666 ± 0.042	0.39TyrTrp: 0.39 ± 0.018	0.632TyrTyr: 0.632 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4001 proteins (1224542 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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