Amino acid dipepetide frequency for Elicom virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.025AlaAla: 4.025 ± 0.829
0.447AlaCys: 0.447 ± 0.206
2.683AlaAsp: 2.683 ± 1.838
2.683AlaGlu: 2.683 ± 0.211
0.894AlaPhe: 0.894 ± 0.412
3.131AlaGly: 3.131 ± 1.632
2.236AlaHis: 2.236 ± 0.005
3.578AlaIle: 3.578 ± 2.451
4.919AlaLys: 4.919 ± 0.808
3.131AlaLeu: 3.131 ± 1.442
1.789AlaMet: 1.789 ± 0.201
2.683AlaAsn: 2.683 ± 0.814
1.789AlaPro: 1.789 ± 0.201
3.131AlaGln: 3.131 ± 0.608
0.447AlaArg: 0.447 ± 0.819
1.789AlaSer: 1.789 ± 1.226
3.131AlaThr: 3.131 ± 0.417
2.236AlaVal: 2.236 ± 1.02
0.894AlaTrp: 0.894 ± 0.412
2.683AlaTyr: 2.683 ± 1.236
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.447CysCys: 0.447 ± 0.206
1.342CysAsp: 1.342 ± 0.618
1.789CysGlu: 1.789 ± 0.824
0.447CysPhe: 0.447 ± 0.206
0.894CysGly: 0.894 ± 0.412
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.894CysLys: 0.894 ± 0.412
1.342CysLeu: 1.342 ± 0.407
0.0CysMet: 0.0 ± 0.0
0.894CysAsn: 0.894 ± 0.412
1.342CysPro: 1.342 ± 0.618
0.447CysGln: 0.447 ± 0.206
0.0CysArg: 0.0 ± 0.0
0.894CysSer: 0.894 ± 0.613
0.447CysThr: 0.447 ± 0.206
0.894CysVal: 0.894 ± 0.412
0.0CysTrp: 0.0 ± 0.0
1.342CysTyr: 1.342 ± 0.618
0.0CysXaa: 0.0 ± 0.0
Asp
4.472AspAla: 4.472 ± 3.064
1.342AspCys: 1.342 ± 0.618
4.472AspAsp: 4.472 ± 1.035
4.472AspGlu: 4.472 ± 2.06
3.578AspPhe: 3.578 ± 0.623
2.683AspGly: 2.683 ± 0.814
1.789AspHis: 1.789 ± 0.824
5.367AspIle: 5.367 ± 0.423
6.261AspLys: 6.261 ± 1.859
3.131AspLeu: 3.131 ± 0.417
0.894AspMet: 0.894 ± 0.1
3.578AspAsn: 3.578 ± 0.401
3.131AspPro: 3.131 ± 2.657
1.342AspGln: 1.342 ± 0.407
1.342AspArg: 1.342 ± 0.618
2.683AspSer: 2.683 ± 1.236
3.131AspThr: 3.131 ± 0.608
4.025AspVal: 4.025 ± 0.829
0.894AspTrp: 0.894 ± 1.638
3.131AspTyr: 3.131 ± 1.442
0.0AspXaa: 0.0 ± 0.0
Glu
2.236GluAla: 2.236 ± 0.005
0.894GluCys: 0.894 ± 0.412
5.367GluAsp: 5.367 ± 0.602
4.025GluGlu: 4.025 ± 0.195
3.131GluPhe: 3.131 ± 0.417
1.789GluGly: 1.789 ± 0.201
2.683GluHis: 2.683 ± 0.211
6.261GluIle: 6.261 ± 1.215
9.392GluLys: 9.392 ± 2.277
3.578GluLeu: 3.578 ± 1.648
1.342GluMet: 1.342 ± 0.618
3.578GluAsn: 3.578 ± 0.401
2.683GluPro: 2.683 ± 0.814
0.894GluGln: 0.894 ± 0.613
1.342GluArg: 1.342 ± 0.618
5.367GluSer: 5.367 ± 2.472
3.131GluThr: 3.131 ± 0.417
3.578GluVal: 3.578 ± 0.623
0.894GluTrp: 0.894 ± 0.412
1.789GluTyr: 1.789 ± 0.201
0.0GluXaa: 0.0 ± 0.0
Phe
3.578PheAla: 3.578 ± 1.648
0.0PheCys: 0.0 ± 0.0
3.578PheAsp: 3.578 ± 1.648
2.236PheGlu: 2.236 ± 0.005
1.342PhePhe: 1.342 ± 0.618
2.236PheGly: 2.236 ± 1.03
1.342PheHis: 1.342 ± 1.432
4.472PheIle: 4.472 ± 3.064
3.578PheLys: 3.578 ± 0.623
2.683PheLeu: 2.683 ± 0.211
0.447PheMet: 0.447 ± 0.206
1.342PheAsn: 1.342 ± 0.407
1.789PhePro: 1.789 ± 0.824
3.131PheGln: 3.131 ± 0.608
1.342PheArg: 1.342 ± 0.618
3.131PheSer: 3.131 ± 1.632
3.578PheThr: 3.578 ± 0.401
3.131PheVal: 3.131 ± 0.417
0.0PheTrp: 0.0 ± 0.0
0.894PheTyr: 0.894 ± 0.412
0.0PheXaa: 0.0 ± 0.0
Gly
2.683GlyAla: 2.683 ± 1.236
0.894GlyCys: 0.894 ± 0.412
1.342GlyAsp: 1.342 ± 0.407
3.578GlyGlu: 3.578 ± 0.401
2.236GlyPhe: 2.236 ± 1.02
2.236GlyGly: 2.236 ± 1.02
2.236GlyHis: 2.236 ± 1.03
2.236GlyIle: 2.236 ± 0.005
4.025GlyLys: 4.025 ± 0.829
4.472GlyLeu: 4.472 ± 1.035
0.894GlyMet: 0.894 ± 0.412
4.025GlyAsn: 4.025 ± 1.22
3.131GlyPro: 3.131 ± 2.657
1.342GlyGln: 1.342 ± 0.407
3.131GlyArg: 3.131 ± 0.608
2.683GlySer: 2.683 ± 1.236
3.578GlyThr: 3.578 ± 3.476
4.472GlyVal: 4.472 ± 3.064
0.447GlyTrp: 0.447 ± 0.206
2.236GlyTyr: 2.236 ± 1.02
0.0GlyXaa: 0.0 ± 0.0
His
1.789HisAla: 1.789 ± 0.201
0.0HisCys: 0.0 ± 0.0
0.447HisAsp: 0.447 ± 0.206
0.894HisGlu: 0.894 ± 0.412
2.236HisPhe: 2.236 ± 1.03
1.342HisGly: 1.342 ± 0.618
0.894HisHis: 0.894 ± 0.412
2.236HisIle: 2.236 ± 1.03
2.236HisLys: 2.236 ± 1.03
4.472HisLeu: 4.472 ± 1.035
0.894HisMet: 0.894 ± 0.412
1.789HisAsn: 1.789 ± 0.824
0.894HisPro: 0.894 ± 0.412
0.447HisGln: 0.447 ± 0.206
0.447HisArg: 0.447 ± 0.819
4.025HisSer: 4.025 ± 0.195
1.342HisThr: 1.342 ± 0.618
1.342HisVal: 1.342 ± 1.432
0.447HisTrp: 0.447 ± 0.206
1.789HisTyr: 1.789 ± 1.226
0.0HisXaa: 0.0 ± 0.0
Ile
5.367IleAla: 5.367 ± 1.627
1.342IleCys: 1.342 ± 0.618
4.919IleAsp: 4.919 ± 0.808
6.261IleGlu: 6.261 ± 0.19
3.131IlePhe: 3.131 ± 0.608
3.578IleGly: 3.578 ± 0.623
2.236IleHis: 2.236 ± 1.03
7.156IleIle: 7.156 ± 2.271
5.367IleLys: 5.367 ± 1.447
4.919IleLeu: 4.919 ± 0.808
2.236IleMet: 2.236 ± 0.005
6.708IleAsn: 6.708 ± 1.041
5.367IlePro: 5.367 ± 0.602
2.683IleGln: 2.683 ± 0.211
3.131IleArg: 3.131 ± 1.632
2.236IleSer: 2.236 ± 1.02
1.789IleThr: 1.789 ± 1.226
5.814IleVal: 5.814 ± 0.629
0.0IleTrp: 0.0 ± 0.0
3.578IleTyr: 3.578 ± 0.623
0.0IleXaa: 0.0 ± 0.0
Lys
2.236LysAla: 2.236 ± 1.02
0.894LysCys: 0.894 ± 0.412
3.578LysAsp: 3.578 ± 1.648
4.919LysGlu: 4.919 ± 0.808
2.236LysPhe: 2.236 ± 0.005
5.814LysGly: 5.814 ± 1.653
4.472LysHis: 4.472 ± 1.035
7.156LysIle: 7.156 ± 2.271
3.578LysLys: 3.578 ± 0.623
4.919LysLeu: 4.919 ± 2.266
2.236LysMet: 2.236 ± 1.03
7.156LysAsn: 7.156 ± 0.803
3.578LysPro: 3.578 ± 0.401
4.472LysGln: 4.472 ± 2.06
3.131LysArg: 3.131 ± 1.442
3.131LysSer: 3.131 ± 1.442
7.603LysThr: 7.603 ± 0.428
4.919LysVal: 4.919 ± 2.266
1.789LysTrp: 1.789 ± 0.824
3.578LysTyr: 3.578 ± 0.623
0.0LysXaa: 0.0 ± 0.0
Leu
4.472LeuAla: 4.472 ± 1.035
0.894LeuCys: 0.894 ± 0.412
4.025LeuAsp: 4.025 ± 0.829
4.472LeuGlu: 4.472 ± 1.035
2.683LeuPhe: 2.683 ± 0.211
3.578LeuGly: 3.578 ± 0.623
1.342LeuHis: 1.342 ± 0.407
6.708LeuIle: 6.708 ± 0.016
6.261LeuLys: 6.261 ± 0.835
3.578LeuLeu: 3.578 ± 0.623
1.789LeuMet: 1.789 ± 0.824
3.578LeuAsn: 3.578 ± 0.401
5.814LeuPro: 5.814 ± 4.495
1.342LeuGln: 1.342 ± 0.618
3.578LeuArg: 3.578 ± 1.648
5.814LeuSer: 5.814 ± 0.629
6.261LeuThr: 6.261 ± 0.835
4.472LeuVal: 4.472 ± 2.06
0.894LeuTrp: 0.894 ± 0.412
1.789LeuTyr: 1.789 ± 0.824
0.0LeuXaa: 0.0 ± 0.0
Met
0.894MetAla: 0.894 ± 0.412
0.0MetCys: 0.0 ± 0.0
1.789MetAsp: 1.789 ± 0.824
1.342MetGlu: 1.342 ± 0.618
0.447MetPhe: 0.447 ± 0.206
0.0MetGly: 0.0 ± 0.0
0.894MetHis: 0.894 ± 0.613
1.789MetIle: 1.789 ± 0.824
1.342MetLys: 1.342 ± 0.618
1.342MetLeu: 1.342 ± 0.618
2.236MetMet: 2.236 ± 1.03
0.894MetAsn: 0.894 ± 0.412
0.447MetPro: 0.447 ± 0.819
0.447MetGln: 0.447 ± 0.206
0.894MetArg: 0.894 ± 0.412
2.236MetSer: 2.236 ± 1.03
1.789MetThr: 1.789 ± 0.201
1.342MetVal: 1.342 ± 0.407
0.447MetTrp: 0.447 ± 0.819
1.789MetTyr: 1.789 ± 0.201
0.0MetXaa: 0.0 ± 0.0
Asn
2.683AsnAla: 2.683 ± 0.211
1.789AsnCys: 1.789 ± 0.824
3.578AsnAsp: 3.578 ± 0.623
4.472AsnGlu: 4.472 ± 0.011
4.472AsnPhe: 4.472 ± 1.014
3.131AsnGly: 3.131 ± 1.632
1.789AsnHis: 1.789 ± 0.824
2.683AsnIle: 2.683 ± 0.814
4.472AsnLys: 4.472 ± 2.06
5.814AsnLeu: 5.814 ± 0.396
1.789AsnMet: 1.789 ± 2.25
3.131AsnAsn: 3.131 ± 0.608
3.131AsnPro: 3.131 ± 0.608
2.683AsnGln: 2.683 ± 1.236
1.342AsnArg: 1.342 ± 2.456
4.472AsnSer: 4.472 ± 0.011
3.131AsnThr: 3.131 ± 0.608
4.919AsnVal: 4.919 ± 2.266
1.789AsnTrp: 1.789 ± 0.201
3.578AsnTyr: 3.578 ± 0.623
0.0AsnXaa: 0.0 ± 0.0
Pro
3.131ProAla: 3.131 ± 2.657
0.447ProCys: 0.447 ± 0.206
2.683ProAsp: 2.683 ± 0.814
3.131ProGlu: 3.131 ± 0.417
0.894ProPhe: 0.894 ± 0.412
4.472ProGly: 4.472 ± 4.089
0.894ProHis: 0.894 ± 0.412
3.578ProIle: 3.578 ± 0.401
1.789ProLys: 1.789 ± 0.201
1.789ProLeu: 1.789 ± 2.25
0.0ProMet: 0.0 ± 0.0
3.578ProAsn: 3.578 ± 0.623
2.683ProPro: 2.683 ± 1.838
2.683ProGln: 2.683 ± 0.814
2.236ProArg: 2.236 ± 0.005
2.683ProSer: 2.683 ± 2.863
3.578ProThr: 3.578 ± 1.426
3.131ProVal: 3.131 ± 0.608
0.447ProTrp: 0.447 ± 0.206
1.342ProTyr: 1.342 ± 1.432
0.0ProXaa: 0.0 ± 0.0
Gln
0.894GlnAla: 0.894 ± 1.638
1.342GlnCys: 1.342 ± 0.407
3.131GlnAsp: 3.131 ± 0.608
0.447GlnGlu: 0.447 ± 0.206
1.789GlnPhe: 1.789 ± 1.226
3.131GlnGly: 3.131 ± 1.632
1.342GlnHis: 1.342 ± 0.618
2.683GlnIle: 2.683 ± 0.211
3.131GlnLys: 3.131 ± 1.442
2.683GlnLeu: 2.683 ± 0.211
1.342GlnMet: 1.342 ± 0.618
3.131GlnAsn: 3.131 ± 0.608
3.131GlnPro: 3.131 ± 0.608
0.894GlnGln: 0.894 ± 0.613
1.789GlnArg: 1.789 ± 0.201
0.894GlnSer: 0.894 ± 0.412
0.447GlnThr: 0.447 ± 0.206
2.236GlnVal: 2.236 ± 0.005
0.447GlnTrp: 0.447 ± 0.206
1.342GlnTyr: 1.342 ± 0.618
0.0GlnXaa: 0.0 ± 0.0
Arg
0.447ArgAla: 0.447 ± 0.206
0.447ArgCys: 0.447 ± 0.206
2.236ArgAsp: 2.236 ± 1.03
1.789ArgGlu: 1.789 ± 0.824
1.789ArgPhe: 1.789 ± 1.226
3.131ArgGly: 3.131 ± 1.632
1.342ArgHis: 1.342 ± 0.618
3.578ArgIle: 3.578 ± 0.623
2.683ArgLys: 2.683 ± 0.211
2.683ArgLeu: 2.683 ± 1.236
0.447ArgMet: 0.447 ± 0.206
4.919ArgAsn: 4.919 ± 1.241
1.789ArgPro: 1.789 ± 0.201
1.789ArgGln: 1.789 ± 1.226
2.683ArgArg: 2.683 ± 1.838
4.919ArgSer: 4.919 ± 0.808
1.789ArgThr: 1.789 ± 0.201
0.894ArgVal: 0.894 ± 0.613
0.447ArgTrp: 0.447 ± 0.206
2.236ArgTyr: 2.236 ± 1.02
0.0ArgXaa: 0.0 ± 0.0
Ser
2.236SerAla: 2.236 ± 0.005
1.342SerCys: 1.342 ± 0.407
4.472SerAsp: 4.472 ± 1.014
3.578SerGlu: 3.578 ± 0.623
1.789SerPhe: 1.789 ± 0.824
2.683SerGly: 2.683 ± 0.814
1.789SerHis: 1.789 ± 0.824
3.131SerIle: 3.131 ± 0.608
3.578SerLys: 3.578 ± 1.648
6.708SerLeu: 6.708 ± 1.041
0.447SerMet: 0.447 ± 0.206
3.578SerAsn: 3.578 ± 0.401
0.0SerPro: 0.0 ± 0.0
0.894SerGln: 0.894 ± 0.412
4.025SerArg: 4.025 ± 0.829
2.683SerSer: 2.683 ± 0.814
7.156SerThr: 7.156 ± 4.902
5.367SerVal: 5.367 ± 0.423
1.789SerTrp: 1.789 ± 0.824
2.236SerTyr: 2.236 ± 1.03
0.0SerXaa: 0.0 ± 0.0
Thr
3.578ThrAla: 3.578 ± 1.426
0.0ThrCys: 0.0 ± 0.0
5.367ThrAsp: 5.367 ± 1.627
4.025ThrGlu: 4.025 ± 0.195
5.814ThrPhe: 5.814 ± 0.629
2.236ThrGly: 2.236 ± 0.005
0.447ThrHis: 0.447 ± 0.206
4.919ThrIle: 4.919 ± 0.808
4.919ThrLys: 4.919 ± 0.217
6.261ThrLeu: 6.261 ± 0.19
0.894ThrMet: 0.894 ± 0.412
3.578ThrAsn: 3.578 ± 0.401
1.342ThrPro: 1.342 ± 1.432
3.578ThrGln: 3.578 ± 1.426
3.578ThrArg: 3.578 ± 0.401
3.131ThrSer: 3.131 ± 0.608
2.236ThrThr: 2.236 ± 0.005
3.578ThrVal: 3.578 ± 2.451
0.894ThrTrp: 0.894 ± 0.613
2.236ThrTyr: 2.236 ± 0.005
0.0ThrXaa: 0.0 ± 0.0
Val
1.342ValAla: 1.342 ± 0.407
0.447ValCys: 0.447 ± 0.206
4.025ValAsp: 4.025 ± 0.195
7.156ValGlu: 7.156 ± 1.247
2.683ValPhe: 2.683 ± 0.814
3.131ValGly: 3.131 ± 0.417
0.894ValHis: 0.894 ± 0.412
4.472ValIle: 4.472 ± 1.035
7.603ValLys: 7.603 ± 0.597
4.025ValLeu: 4.025 ± 1.22
0.894ValMet: 0.894 ± 0.412
3.578ValAsn: 3.578 ± 0.623
2.683ValPro: 2.683 ± 0.814
1.789ValGln: 1.789 ± 1.226
2.683ValArg: 2.683 ± 0.211
2.683ValSer: 2.683 ± 0.211
5.814ValThr: 5.814 ± 1.421
3.131ValVal: 3.131 ± 0.417
0.894ValTrp: 0.894 ± 0.613
3.131ValTyr: 3.131 ± 1.442
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.894TrpGlu: 0.894 ± 1.638
0.447TrpPhe: 0.447 ± 0.206
0.0TrpGly: 0.0 ± 0.0
0.447TrpHis: 0.447 ± 0.819
2.236TrpIle: 2.236 ± 0.005
1.789TrpLys: 1.789 ± 0.824
0.894TrpLeu: 0.894 ± 0.412
0.0TrpMet: 0.0 ± 0.0
0.894TrpAsn: 0.894 ± 0.613
0.0TrpPro: 0.0 ± 0.0
0.447TrpGln: 0.447 ± 0.206
1.342TrpArg: 1.342 ± 0.618
1.789TrpSer: 1.789 ± 0.201
0.894TrpThr: 0.894 ± 0.412
2.236TrpVal: 2.236 ± 1.02
0.447TrpTrp: 0.447 ± 0.206
0.447TrpTyr: 0.447 ± 0.206
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.236TyrAla: 2.236 ± 0.005
0.447TyrCys: 0.447 ± 0.206
3.131TyrAsp: 3.131 ± 1.442
1.789TyrGlu: 1.789 ± 0.824
1.789TyrPhe: 1.789 ± 0.824
2.683TyrGly: 2.683 ± 0.814
0.894TyrHis: 0.894 ± 0.613
3.578TyrIle: 3.578 ± 0.623
3.578TyrLys: 3.578 ± 1.648
4.919TyrLeu: 4.919 ± 1.241
1.342TyrMet: 1.342 ± 0.618
2.236TyrAsn: 2.236 ± 0.005
0.447TyrPro: 0.447 ± 0.819
1.789TyrGln: 1.789 ± 0.201
3.578TyrArg: 3.578 ± 0.401
2.236TyrSer: 2.236 ± 1.03
1.789TyrThr: 1.789 ± 0.824
1.342TyrVal: 1.342 ± 0.407
1.342TyrTrp: 1.342 ± 1.432
2.236TyrTyr: 2.236 ± 0.005
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2237 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski