Amino acid dipepetide frequency for Vombatus ursinus (Common wombat)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.892AlaAla: 5.892 ± 0.03	1.285AlaCys: 1.285 ± 0.011	2.761AlaAsp: 2.761 ± 0.013	4.398AlaGlu: 4.398 ± 0.026	2.698AlaPhe: 2.698 ± 0.017	4.148AlaGly: 4.148 ± 0.021	1.432AlaHis: 1.432 ± 0.009	2.878AlaIle: 2.878 ± 0.015	3.393AlaLys: 3.393 ± 0.018	6.764AlaLeu: 6.764 ± 0.027	1.446AlaMet: 1.446 ± 0.009	2.072AlaAsn: 2.072 ± 0.011	3.516AlaPro: 3.516 ± 0.027	2.963AlaGln: 2.963 ± 0.02	3.181AlaArg: 3.181 ± 0.016	5.436AlaSer: 5.436 ± 0.021	3.29AlaThr: 3.29 ± 0.014	4.372AlaVal: 4.372 ± 0.019	0.739AlaTrp: 0.739 ± 0.007	1.522AlaTyr: 1.522 ± 0.011	0.001AlaXaa: 0.001 ± 0.0
Cys	1.159CysAla: 1.159 ± 0.01	0.612CysCys: 0.612 ± 0.009	1.057CysAsp: 1.057 ± 0.011	1.277CysGlu: 1.277 ± 0.012	0.876CysPhe: 0.876 ± 0.007	1.735CysGly: 1.735 ± 0.021	0.681CysHis: 0.681 ± 0.008	1.026CysIle: 1.026 ± 0.01	1.189CysLys: 1.189 ± 0.011	2.189CysLeu: 2.189 ± 0.013	0.428CysMet: 0.428 ± 0.005	0.986CysAsn: 0.986 ± 0.012	1.335CysPro: 1.335 ± 0.016	1.095CysGln: 1.095 ± 0.012	1.21CysArg: 1.21 ± 0.01	1.972CysSer: 1.972 ± 0.015	1.089CysThr: 1.089 ± 0.009	1.262CysVal: 1.262 ± 0.011	0.278CysTrp: 0.278 ± 0.005	0.609CysTyr: 0.609 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	2.673AspAla: 2.673 ± 0.015	1.062AspCys: 1.062 ± 0.011	2.696AspAsp: 2.696 ± 0.018	3.505AspGlu: 3.505 ± 0.019	2.182AspPhe: 2.182 ± 0.012	3.306AspGly: 3.306 ± 0.017	1.153AspHis: 1.153 ± 0.008	2.731AspIle: 2.731 ± 0.014	2.577AspLys: 2.577 ± 0.016	5.081AspLeu: 5.081 ± 0.019	1.118AspMet: 1.118 ± 0.008	1.8AspAsn: 1.8 ± 0.011	2.817AspPro: 2.817 ± 0.014	1.905AspGln: 1.905 ± 0.011	2.376AspArg: 2.376 ± 0.013	4.162AspSer: 4.162 ± 0.021	2.421AspThr: 2.421 ± 0.013	3.032AspVal: 3.032 ± 0.015	0.643AspTrp: 0.643 ± 0.006	1.534AspTyr: 1.534 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	4.865GluAla: 4.865 ± 0.028	1.567GluCys: 1.567 ± 0.022	4.379GluAsp: 4.379 ± 0.02	7.909GluGlu: 7.909 ± 0.046	2.1GluPhe: 2.1 ± 0.012	4.136GluGly: 4.136 ± 0.018	1.523GluHis: 1.523 ± 0.009	3.379GluIle: 3.379 ± 0.017	5.788GluLys: 5.788 ± 0.038	6.483GluLeu: 6.483 ± 0.032	1.752GluMet: 1.752 ± 0.01	3.306GluAsn: 3.306 ± 0.018	2.999GluPro: 2.999 ± 0.017	3.113GluGln: 3.113 ± 0.017	3.961GluArg: 3.961 ± 0.025	4.503GluSer: 4.503 ± 0.021	3.476GluThr: 3.476 ± 0.014	4.131GluVal: 4.131 ± 0.017	0.697GluTrp: 0.697 ± 0.007	1.635GluTyr: 1.635 ± 0.012	0.001GluXaa: 0.001 ± 0.0
Phe	1.974PheAla: 1.974 ± 0.011	0.96PheCys: 0.96 ± 0.009	1.751PheAsp: 1.751 ± 0.011	2.044PheGlu: 2.044 ± 0.011	1.77PhePhe: 1.77 ± 0.016	2.28PheGly: 2.28 ± 0.017	1.083PheHis: 1.083 ± 0.008	2.005PheIle: 2.005 ± 0.013	1.842PheLys: 1.842 ± 0.012	4.347PheLeu: 4.347 ± 0.023	0.789PheMet: 0.789 ± 0.007	1.417PheAsn: 1.417 ± 0.009	2.064PhePro: 2.064 ± 0.013	1.871PheGln: 1.871 ± 0.011	1.982PheArg: 1.982 ± 0.013	3.62PheSer: 3.62 ± 0.017	2.143PheThr: 2.143 ± 0.014	2.203PheVal: 2.203 ± 0.012	0.504PheTrp: 0.504 ± 0.006	1.262PheTyr: 1.262 ± 0.01	0.001PheXaa: 0.001 ± 0.0
Gly	3.971GlyAla: 3.971 ± 0.022	1.215GlyCys: 1.215 ± 0.01	3.084GlyAsp: 3.084 ± 0.015	4.239GlyGlu: 4.239 ± 0.027	2.423GlyPhe: 2.423 ± 0.014	4.928GlyGly: 4.928 ± 0.036	1.666GlyHis: 1.666 ± 0.011	2.954GlyIle: 2.954 ± 0.016	3.99GlyLys: 3.99 ± 0.02	5.663GlyLeu: 5.663 ± 0.021	1.328GlyMet: 1.328 ± 0.009	2.539GlyAsn: 2.539 ± 0.014	3.816GlyPro: 3.816 ± 0.04	2.737GlyGln: 2.737 ± 0.017	3.494GlyArg: 3.494 ± 0.02	5.639GlySer: 5.639 ± 0.024	3.522GlyThr: 3.522 ± 0.021	3.413GlyVal: 3.413 ± 0.018	0.78GlyTrp: 0.78 ± 0.009	1.787GlyTyr: 1.787 ± 0.012	0.002GlyXaa: 0.002 ± 0.0
His	1.238HisAla: 1.238 ± 0.009	0.73HisCys: 0.73 ± 0.008	0.891HisAsp: 0.891 ± 0.008	1.348HisGlu: 1.348 ± 0.009	1.124HisPhe: 1.124 ± 0.01	1.511HisGly: 1.511 ± 0.011	0.919HisHis: 0.919 ± 0.01	1.336HisIle: 1.336 ± 0.01	1.31HisLys: 1.31 ± 0.01	2.938HisLeu: 2.938 ± 0.014	0.576HisMet: 0.576 ± 0.006	0.929HisAsn: 0.929 ± 0.007	1.599HisPro: 1.599 ± 0.011	1.516HisGln: 1.516 ± 0.013	1.523HisArg: 1.523 ± 0.011	2.313HisSer: 2.313 ± 0.012	1.557HisThr: 1.557 ± 0.016	1.449HisVal: 1.449 ± 0.01	0.356HisTrp: 0.356 ± 0.005	0.833HisTyr: 0.833 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.676IleAla: 2.676 ± 0.014	1.168IleCys: 1.168 ± 0.009	2.198IleAsp: 2.198 ± 0.015	2.743IleGlu: 2.743 ± 0.016	2.077IlePhe: 2.077 ± 0.014	2.399IleGly: 2.399 ± 0.013	1.552IleHis: 1.552 ± 0.015	2.66IleIle: 2.66 ± 0.014	2.773IleLys: 2.773 ± 0.015	4.993IleLeu: 4.993 ± 0.023	1.072IleMet: 1.072 ± 0.009	1.993IleAsn: 1.993 ± 0.013	2.779IlePro: 2.779 ± 0.014	2.494IleGln: 2.494 ± 0.015	2.484IleArg: 2.484 ± 0.013	4.04IleSer: 4.04 ± 0.017	2.761IleThr: 2.761 ± 0.015	2.633IleVal: 2.633 ± 0.014	0.559IleTrp: 0.559 ± 0.006	1.505IleTyr: 1.505 ± 0.011	0.001IleXaa: 0.001 ± 0.0
Lys	4.032LysAla: 4.032 ± 0.022	1.222LysCys: 1.222 ± 0.012	3.239LysAsp: 3.239 ± 0.017	5.338LysGlu: 5.338 ± 0.031	1.777LysPhe: 1.777 ± 0.011	3.338LysGly: 3.338 ± 0.02	1.449LysHis: 1.449 ± 0.011	3.001LysIle: 3.001 ± 0.018	4.895LysLys: 4.895 ± 0.027	5.419LysLeu: 5.419 ± 0.025	1.511LysMet: 1.511 ± 0.01	2.585LysAsn: 2.585 ± 0.014	3.174LysPro: 3.174 ± 0.023	2.698LysGln: 2.698 ± 0.015	3.303LysArg: 3.303 ± 0.018	4.049LysSer: 4.049 ± 0.02	3.188LysThr: 3.188 ± 0.015	3.602LysVal: 3.602 ± 0.017	0.645LysTrp: 0.645 ± 0.006	1.635LysTyr: 1.635 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	6.433LeuAla: 6.433 ± 0.025	2.155LeuCys: 2.155 ± 0.012	4.802LeuAsp: 4.802 ± 0.021	7.281LeuGlu: 7.281 ± 0.039	3.577LeuPhe: 3.577 ± 0.022	5.763LeuGly: 5.763 ± 0.023	2.769LeuHis: 2.769 ± 0.017	4.27LeuIle: 4.27 ± 0.022	6.075LeuLys: 6.075 ± 0.028	10.75LeuLeu: 10.75 ± 0.047	2.069LeuMet: 2.069 ± 0.011	3.812LeuAsn: 3.812 ± 0.016	5.849LeuPro: 5.849 ± 0.025	5.743LeuGln: 5.743 ± 0.03	5.688LeuArg: 5.688 ± 0.026	8.114LeuSer: 8.114 ± 0.03	5.278LeuThr: 5.278 ± 0.02	5.514LeuVal: 5.514 ± 0.022	1.146LeuTrp: 1.146 ± 0.008	2.663LeuTyr: 2.663 ± 0.014	0.001LeuXaa: 0.001 ± 0.0
Met	1.841MetAla: 1.841 ± 0.011	0.4MetCys: 0.4 ± 0.006	1.278MetAsp: 1.278 ± 0.008	1.94MetGlu: 1.94 ± 0.011	0.767MetPhe: 0.767 ± 0.008	1.315MetGly: 1.315 ± 0.009	0.464MetHis: 0.464 ± 0.005	0.941MetIle: 0.941 ± 0.008	1.538MetLys: 1.538 ± 0.01	2.024MetLeu: 2.024 ± 0.012	0.614MetMet: 0.614 ± 0.007	0.958MetAsn: 0.958 ± 0.008	1.062MetPro: 1.062 ± 0.009	0.933MetGln: 0.933 ± 0.008	1.001MetArg: 1.001 ± 0.008	1.582MetSer: 1.582 ± 0.009	1.177MetThr: 1.177 ± 0.008	1.415MetVal: 1.415 ± 0.01	0.241MetTrp: 0.241 ± 0.004	0.616MetTyr: 0.616 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.069AsnAla: 2.069 ± 0.012	0.91AsnCys: 0.91 ± 0.009	1.625AsnAsp: 1.625 ± 0.01	2.508AsnGlu: 2.508 ± 0.015	1.61AsnPhe: 1.61 ± 0.009	2.597AsnGly: 2.597 ± 0.015	1.026AsnHis: 1.026 ± 0.008	2.312AsnIle: 2.312 ± 0.014	2.363AsnLys: 2.363 ± 0.014	4.01AsnLeu: 4.01 ± 0.017	0.965AsnMet: 0.965 ± 0.007	1.664AsnAsn: 1.664 ± 0.011	2.251AsnPro: 2.251 ± 0.012	1.81AsnGln: 1.81 ± 0.011	1.919AsnArg: 1.919 ± 0.01	3.366AsnSer: 3.366 ± 0.02	2.09AsnThr: 2.09 ± 0.011	2.337AsnVal: 2.337 ± 0.012	0.484AsnTrp: 0.484 ± 0.006	1.186AsnTyr: 1.186 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	4.11ProAla: 4.11 ± 0.028	1.091ProCys: 1.091 ± 0.012	2.718ProAsp: 2.718 ± 0.013	4.199ProGlu: 4.199 ± 0.018	2.009ProPhe: 2.009 ± 0.014	4.75ProGly: 4.75 ± 0.054	1.409ProHis: 1.409 ± 0.01	2.02ProIle: 2.02 ± 0.013	2.795ProLys: 2.795 ± 0.018	5.183ProLeu: 5.183 ± 0.022	1.045ProMet: 1.045 ± 0.008	1.954ProAsn: 1.954 ± 0.012	5.641ProPro: 5.641 ± 0.054	2.691ProGln: 2.691 ± 0.019	2.966ProArg: 2.966 ± 0.019	5.5ProSer: 5.5 ± 0.03	2.97ProThr: 2.97 ± 0.018	3.624ProVal: 3.624 ± 0.021	0.66ProTrp: 0.66 ± 0.006	1.583ProTyr: 1.583 ± 0.014	0.001ProXaa: 0.001 ± 0.0
Gln	3.274GlnAla: 3.274 ± 0.019	1.003GlnCys: 1.003 ± 0.01	2.312GlnAsp: 2.312 ± 0.011	3.886GlnGlu: 3.886 ± 0.024	1.414GlnPhe: 1.414 ± 0.009	2.768GlnGly: 2.768 ± 0.018	1.361GlnHis: 1.361 ± 0.011	2.15GlnIle: 2.15 ± 0.014	3.068GlnLys: 3.068 ± 0.02	4.81GlnLeu: 4.81 ± 0.028	1.146GlnMet: 1.146 ± 0.009	1.99GlnAsn: 1.99 ± 0.012	2.617GlnPro: 2.617 ± 0.019	3.121GlnGln: 3.121 ± 0.032	2.939GlnArg: 2.939 ± 0.016	3.232GlnSer: 3.232 ± 0.016	2.327GlnThr: 2.327 ± 0.014	2.824GlnVal: 2.824 ± 0.014	0.552GlnTrp: 0.552 ± 0.005	1.213GlnTyr: 1.213 ± 0.01	0.001GlnXaa: 0.001 ± 0.0
Arg	3.426ArgAla: 3.426 ± 0.018	1.156ArgCys: 1.156 ± 0.012	2.636ArgAsp: 2.636 ± 0.014	3.856ArgGlu: 3.856 ± 0.024	1.837ArgPhe: 1.837 ± 0.01	3.316ArgGly: 3.316 ± 0.021	1.469ArgHis: 1.469 ± 0.009	2.62ArgIle: 2.62 ± 0.015	3.677ArgLys: 3.677 ± 0.02	5.171ArgLeu: 5.171 ± 0.024	1.166ArgMet: 1.166 ± 0.007	2.182ArgAsn: 2.182 ± 0.013	2.859ArgPro: 2.859 ± 0.02	2.549ArgGln: 2.549 ± 0.014	3.966ArgArg: 3.966 ± 0.023	4.056ArgSer: 4.056 ± 0.027	2.752ArgThr: 2.752 ± 0.013	3.003ArgVal: 3.003 ± 0.015	0.661ArgTrp: 0.661 ± 0.006	1.491ArgTyr: 1.491 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	4.914SerAla: 4.914 ± 0.019	1.852SerCys: 1.852 ± 0.014	3.952SerAsp: 3.952 ± 0.018	5.195SerGlu: 5.195 ± 0.021	3.216SerPhe: 3.216 ± 0.015	5.545SerGly: 5.545 ± 0.024	2.176SerHis: 2.176 ± 0.012	3.496SerIle: 3.496 ± 0.018	4.203SerLys: 4.203 ± 0.021	8.393SerLeu: 8.393 ± 0.029	1.636SerMet: 1.636 ± 0.01	2.882SerAsn: 2.882 ± 0.014	5.855SerPro: 5.855 ± 0.034	3.94SerGln: 3.94 ± 0.019	4.335SerArg: 4.335 ± 0.025	9.49SerSer: 9.49 ± 0.051	4.51SerThr: 4.51 ± 0.022	4.889SerVal: 4.889 ± 0.02	1.053SerTrp: 1.053 ± 0.009	2.179SerTyr: 2.179 ± 0.013	0.001SerXaa: 0.001 ± 0.0
Thr	3.561ThrAla: 3.561 ± 0.015	1.305ThrCys: 1.305 ± 0.013	2.509ThrAsp: 2.509 ± 0.011	3.61ThrGlu: 3.61 ± 0.014	2.23ThrPhe: 2.23 ± 0.012	3.597ThrGly: 3.597 ± 0.018	1.27ThrHis: 1.27 ± 0.01	2.604ThrIle: 2.604 ± 0.014	2.743ThrLys: 2.743 ± 0.015	5.412ThrLeu: 5.412 ± 0.021	1.153ThrMet: 1.153 ± 0.007	1.849ThrAsn: 1.849 ± 0.011	3.387ThrPro: 3.387 ± 0.021	2.29ThrGln: 2.29 ± 0.012	2.38ThrArg: 2.38 ± 0.013	4.66ThrSer: 4.66 ± 0.022	2.983ThrThr: 2.983 ± 0.019	3.834ThrVal: 3.834 ± 0.016	0.692ThrTrp: 0.692 ± 0.007	1.489ThrTyr: 1.489 ± 0.008	0.001ThrXaa: 0.001 ± 0.0
Val	3.963ValAla: 3.963 ± 0.019	1.436ValCys: 1.436 ± 0.01	2.872ValAsp: 2.872 ± 0.015	3.832ValGlu: 3.832 ± 0.018	2.468ValPhe: 2.468 ± 0.016	3.315ValGly: 3.315 ± 0.015	1.512ValHis: 1.512 ± 0.01	3.128ValIle: 3.128 ± 0.015	3.455ValLys: 3.455 ± 0.016	6.117ValLeu: 6.117 ± 0.025	1.346ValMet: 1.346 ± 0.011	2.399ValAsn: 2.399 ± 0.013	3.444ValPro: 3.444 ± 0.021	2.7ValGln: 2.7 ± 0.016	2.859ValArg: 2.859 ± 0.012	4.84ValSer: 4.84 ± 0.018	3.797ValThr: 3.797 ± 0.019	3.861ValVal: 3.861 ± 0.02	0.693ValTrp: 0.693 ± 0.008	1.665ValTyr: 1.665 ± 0.011	0.0ValXaa: 0.0 ± 0.0
Trp	0.735TrpAla: 0.735 ± 0.006	0.24TrpCys: 0.24 ± 0.004	0.662TrpAsp: 0.662 ± 0.007	0.814TrpGlu: 0.814 ± 0.007	0.435TrpPhe: 0.435 ± 0.005	0.738TrpGly: 0.738 ± 0.009	0.294TrpHis: 0.294 ± 0.004	0.589TrpIle: 0.589 ± 0.007	0.859TrpLys: 0.859 ± 0.007	1.205TrpLeu: 1.205 ± 0.009	0.317TrpMet: 0.317 ± 0.005	0.586TrpAsn: 0.586 ± 0.006	0.503TrpPro: 0.503 ± 0.006	0.523TrpGln: 0.523 ± 0.005	0.696TrpArg: 0.696 ± 0.007	0.878TrpSer: 0.878 ± 0.009	0.669TrpThr: 0.669 ± 0.007	0.675TrpVal: 0.675 ± 0.007	0.197TrpTrp: 0.197 ± 0.003	0.338TrpTyr: 0.338 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.382TyrAla: 1.382 ± 0.01	0.698TyrCys: 0.698 ± 0.007	1.352TyrAsp: 1.352 ± 0.01	1.781TyrGlu: 1.781 ± 0.012	1.32TyrPhe: 1.32 ± 0.01	1.705TyrGly: 1.705 ± 0.012	0.787TyrHis: 0.787 ± 0.008	1.462TyrIle: 1.462 ± 0.01	1.567TyrLys: 1.567 ± 0.015	2.798TyrLeu: 2.798 ± 0.015	0.626TyrMet: 0.626 ± 0.006	1.197TyrAsn: 1.197 ± 0.009	1.35TyrPro: 1.35 ± 0.011	1.314TyrGln: 1.314 ± 0.01	1.586TyrArg: 1.586 ± 0.011	2.26TyrSer: 2.26 ± 0.012	1.56TyrThr: 1.56 ± 0.011	1.627TyrVal: 1.627 ± 0.011	0.373TyrTrp: 0.373 ± 0.005	0.99TyrTyr: 0.99 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.101XaaXaa: 0.101 ± 0.016

Statistics based on 31139 proteins (18770870 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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