Amino acid dipepetide frequency for Zea mays chrysovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.171AlaAla: 5.171 ± 1.73
2.011AlaCys: 2.011 ± 0.304
4.022AlaAsp: 4.022 ± 0.876
6.033AlaGlu: 6.033 ± 2.955
2.011AlaPhe: 2.011 ± 0.313
5.745AlaGly: 5.745 ± 1.146
1.724AlaHis: 1.724 ± 0.33
3.16AlaIle: 3.16 ± 0.673
4.596AlaLys: 4.596 ± 0.627
4.022AlaLeu: 4.022 ± 0.466
2.298AlaMet: 2.298 ± 0.56
1.724AlaAsn: 1.724 ± 0.563
3.16AlaPro: 3.16 ± 0.624
2.585AlaGln: 2.585 ± 0.448
3.447AlaArg: 3.447 ± 0.623
4.596AlaSer: 4.596 ± 0.352
2.585AlaThr: 2.585 ± 1.034
2.585AlaVal: 2.585 ± 0.275
1.724AlaTrp: 1.724 ± 0.912
4.022AlaTyr: 4.022 ± 0.645
0.0AlaXaa: 0.0 ± 0.0
Cys
0.862CysAla: 0.862 ± 0.35
0.0CysCys: 0.0 ± 0.0
0.862CysAsp: 0.862 ± 0.752
1.149CysGlu: 1.149 ± 0.455
0.287CysPhe: 0.287 ± 0.251
1.149CysGly: 1.149 ± 0.526
0.287CysHis: 0.287 ± 0.203
0.287CysIle: 0.287 ± 0.203
1.436CysLys: 1.436 ± 0.228
1.149CysLeu: 1.149 ± 0.28
0.575CysMet: 0.575 ± 0.236
0.287CysAsn: 0.287 ± 0.252
0.287CysPro: 0.287 ± 0.252
0.0CysGln: 0.0 ± 0.0
1.436CysArg: 1.436 ± 0.53
1.724CysSer: 1.724 ± 0.75
1.149CysThr: 1.149 ± 0.28
0.862CysVal: 0.862 ± 0.047
0.0CysTrp: 0.0 ± 0.0
1.149CysTyr: 1.149 ± 0.455
0.0CysXaa: 0.0 ± 0.0
Asp
4.309AspAla: 4.309 ± 0.511
0.862AspCys: 0.862 ± 0.61
8.044AspAsp: 8.044 ± 2.084
5.458AspGlu: 5.458 ± 1.152
2.298AspPhe: 2.298 ± 1.093
4.022AspGly: 4.022 ± 0.601
1.149AspHis: 1.149 ± 0.526
3.735AspIle: 3.735 ± 0.394
7.182AspLys: 7.182 ± 2.146
4.309AspLeu: 4.309 ± 0.629
2.011AspMet: 2.011 ± 0.498
3.447AspAsn: 3.447 ± 0.563
2.298AspPro: 2.298 ± 0.56
1.436AspGln: 1.436 ± 0.36
4.884AspArg: 4.884 ± 0.484
3.735AspSer: 3.735 ± 0.712
2.011AspThr: 2.011 ± 0.304
7.182AspVal: 7.182 ± 0.488
1.436AspTrp: 1.436 ± 0.228
2.873AspTyr: 2.873 ± 0.593
0.0AspXaa: 0.0 ± 0.0
Glu
5.171GluAla: 5.171 ± 1.759
0.862GluCys: 0.862 ± 0.752
6.32GluAsp: 6.32 ± 1.146
8.618GluGlu: 8.618 ± 0.792
3.447GluPhe: 3.447 ± 0.243
6.607GluGly: 6.607 ± 1.09
1.149GluHis: 1.149 ± 0.455
2.585GluIle: 2.585 ± 0.873
8.618GluLys: 8.618 ± 1.804
7.182GluLeu: 7.182 ± 0.303
2.873GluMet: 2.873 ± 0.859
2.011GluAsn: 2.011 ± 0.438
2.011GluPro: 2.011 ± 0.304
3.16GluGln: 3.16 ± 1.035
5.745GluArg: 5.745 ± 1.146
3.447GluSer: 3.447 ± 0.243
2.011GluThr: 2.011 ± 0.304
6.895GluVal: 6.895 ± 0.923
2.011GluTrp: 2.011 ± 0.684
2.873GluTyr: 2.873 ± 1.113
0.0GluXaa: 0.0 ± 0.0
Phe
2.011PheAla: 2.011 ± 0.304
0.575PheCys: 0.575 ± 0.25
2.011PheAsp: 2.011 ± 0.304
3.735PheGlu: 3.735 ± 0.853
0.862PhePhe: 0.862 ± 0.435
3.16PheGly: 3.16 ± 0.752
0.0PheHis: 0.0 ± 0.0
2.011PheIle: 2.011 ± 0.547
0.575PheLys: 0.575 ± 0.25
1.724PheLeu: 1.724 ± 0.75
0.575PheMet: 0.575 ± 0.228
0.575PheAsn: 0.575 ± 0.228
0.862PhePro: 0.862 ± 0.61
0.575PheGln: 0.575 ± 0.236
1.724PheArg: 1.724 ± 0.475
2.011PheSer: 2.011 ± 0.903
1.436PheThr: 1.436 ± 0.663
2.011PheVal: 2.011 ± 0.699
0.575PheTrp: 0.575 ± 0.228
1.149PheTyr: 1.149 ± 0.68
0.0PheXaa: 0.0 ± 0.0
Gly
4.596GlyAla: 4.596 ± 1.494
1.436GlyCys: 1.436 ± 0.212
5.458GlyAsp: 5.458 ± 0.471
6.033GlyGlu: 6.033 ± 0.968
1.149GlyPhe: 1.149 ± 0.275
5.171GlyGly: 5.171 ± 1.99
0.575GlyHis: 0.575 ± 0.236
3.447GlyIle: 3.447 ± 1.211
6.033GlyLys: 6.033 ± 1.68
7.469GlyLeu: 7.469 ± 0.477
2.585GlyMet: 2.585 ± 0.515
3.16GlyAsn: 3.16 ± 0.974
2.585GlyPro: 2.585 ± 0.895
4.022GlyGln: 4.022 ± 0.261
4.884GlyArg: 4.884 ± 1.222
5.458GlySer: 5.458 ± 0.903
4.022GlyThr: 4.022 ± 0.877
4.309GlyVal: 4.309 ± 0.792
3.16GlyTrp: 3.16 ± 1.135
1.724GlyTyr: 1.724 ± 0.87
0.0GlyXaa: 0.0 ± 0.0
His
1.149HisAla: 1.149 ± 0.157
0.0HisCys: 0.0 ± 0.0
0.575HisAsp: 0.575 ± 0.228
0.862HisGlu: 0.862 ± 0.35
0.287HisPhe: 0.287 ± 0.251
2.011HisGly: 2.011 ± 0.313
0.0HisHis: 0.0 ± 0.0
1.436HisIle: 1.436 ± 0.212
1.724HisLys: 1.724 ± 0.701
1.724HisLeu: 1.724 ± 0.708
1.149HisMet: 1.149 ± 0.157
1.149HisAsn: 1.149 ± 1.008
0.287HisPro: 0.287 ± 0.251
0.287HisGln: 0.287 ± 0.203
1.149HisArg: 1.149 ± 0.526
1.724HisSer: 1.724 ± 0.474
0.575HisThr: 0.575 ± 0.228
0.575HisVal: 0.575 ± 0.228
0.575HisTrp: 0.575 ± 0.236
0.862HisTyr: 0.862 ± 0.047
0.0HisXaa: 0.0 ± 0.0
Ile
2.011IleAla: 2.011 ± 0.772
1.436IleCys: 1.436 ± 0.212
3.16IleAsp: 3.16 ± 0.493
4.884IleGlu: 4.884 ± 1.829
1.436IlePhe: 1.436 ± 0.36
4.022IleGly: 4.022 ± 1.178
0.575IleHis: 0.575 ± 0.228
2.873IleIle: 2.873 ± 0.697
1.436IleLys: 1.436 ± 0.53
2.585IleLeu: 2.585 ± 0.516
0.575IleMet: 0.575 ± 0.504
3.447IleAsn: 3.447 ± 0.243
2.298IlePro: 2.298 ± 0.938
1.149IleGln: 1.149 ± 0.28
2.873IleArg: 2.873 ± 0.744
3.447IleSer: 3.447 ± 0.563
1.436IleThr: 1.436 ± 0.647
0.862IleVal: 0.862 ± 0.047
1.724IleTrp: 1.724 ± 0.33
0.862IleTyr: 0.862 ± 0.443
0.0IleXaa: 0.0 ± 0.0
Lys
6.32LysAla: 6.32 ± 2.675
0.575LysCys: 0.575 ± 0.25
4.309LysAsp: 4.309 ± 1.18
7.469LysGlu: 7.469 ± 0.844
1.724LysPhe: 1.724 ± 0.453
4.596LysGly: 4.596 ± 0.762
1.436LysHis: 1.436 ± 0.663
2.011LysIle: 2.011 ± 0.304
10.629LysLys: 10.629 ± 1.963
4.884LysLeu: 4.884 ± 1.036
2.298LysMet: 2.298 ± 0.204
2.298LysAsn: 2.298 ± 0.551
4.022LysPro: 4.022 ± 1.012
2.298LysGln: 2.298 ± 0.23
5.458LysArg: 5.458 ± 0.923
4.309LysSer: 4.309 ± 0.921
3.735LysThr: 3.735 ± 0.457
3.447LysVal: 3.447 ± 0.461
1.724LysTrp: 1.724 ± 0.708
2.873LysTyr: 2.873 ± 0.72
0.0LysXaa: 0.0 ± 0.0
Leu
6.32LeuAla: 6.32 ± 1.728
2.011LeuCys: 2.011 ± 0.803
6.32LeuAsp: 6.32 ± 0.534
5.458LeuGlu: 5.458 ± 0.849
1.149LeuPhe: 1.149 ± 0.5
7.756LeuGly: 7.756 ± 0.999
2.011LeuHis: 2.011 ± 0.547
2.873LeuIle: 2.873 ± 0.457
4.884LeuLys: 4.884 ± 0.287
4.309LeuLeu: 4.309 ± 1.251
2.873LeuMet: 2.873 ± 0.065
2.585LeuAsn: 2.585 ± 0.796
2.298LeuPro: 2.298 ± 0.685
3.447LeuGln: 3.447 ± 0.69
6.033LeuArg: 6.033 ± 0.517
4.884LeuSer: 4.884 ± 1.232
4.884LeuThr: 4.884 ± 0.484
7.182LeuVal: 7.182 ± 1.319
1.149LeuTrp: 1.149 ± 0.275
3.735LeuTyr: 3.735 ± 1.457
0.0LeuXaa: 0.0 ± 0.0
Met
2.298MetAla: 2.298 ± 0.551
0.575MetCys: 0.575 ± 0.25
1.724MetAsp: 1.724 ± 0.312
2.011MetGlu: 2.011 ± 0.699
0.0MetPhe: 0.0 ± 0.0
2.873MetGly: 2.873 ± 0.781
0.862MetHis: 0.862 ± 0.435
0.575MetIle: 0.575 ± 0.25
2.011MetLys: 2.011 ± 0.772
3.735MetLeu: 3.735 ± 0.762
0.287MetMet: 0.287 ± 0.252
1.436MetAsn: 1.436 ± 0.297
0.862MetPro: 0.862 ± 0.047
0.862MetGln: 0.862 ± 0.047
1.724MetArg: 1.724 ± 0.475
2.011MetSer: 2.011 ± 0.766
0.862MetThr: 0.862 ± 0.047
2.873MetVal: 2.873 ± 0.734
0.287MetTrp: 0.287 ± 0.252
1.436MetTyr: 1.436 ± 0.647
0.0MetXaa: 0.0 ± 0.0
Asn
1.436AsnAla: 1.436 ± 0.297
0.862AsnCys: 0.862 ± 0.047
2.585AsnAsp: 2.585 ± 0.665
2.298AsnGlu: 2.298 ± 0.706
2.585AsnPhe: 2.585 ± 0.908
1.724AsnGly: 1.724 ± 0.474
2.298AsnHis: 2.298 ± 0.313
1.436AsnIle: 1.436 ± 0.526
3.447AsnLys: 3.447 ± 0.563
3.735AsnLeu: 3.735 ± 0.819
0.0AsnMet: 0.0 ± 0.0
1.436AsnAsn: 1.436 ± 0.53
1.149AsnPro: 1.149 ± 0.28
0.287AsnGln: 0.287 ± 0.203
1.724AsnArg: 1.724 ± 0.474
2.873AsnSer: 2.873 ± 0.739
1.436AsnThr: 1.436 ± 0.297
2.298AsnVal: 2.298 ± 0.523
2.585AsnTrp: 2.585 ± 0.301
0.862AsnTyr: 0.862 ± 0.362
0.0AsnXaa: 0.0 ± 0.0
Pro
2.298ProAla: 2.298 ± 0.685
0.575ProCys: 0.575 ± 0.504
3.735ProAsp: 3.735 ± 0.026
2.873ProGlu: 2.873 ± 0.593
1.436ProPhe: 1.436 ± 0.526
3.16ProGly: 3.16 ± 0.529
0.287ProHis: 0.287 ± 0.203
2.298ProIle: 2.298 ± 0.523
2.585ProLys: 2.585 ± 0.141
2.585ProLeu: 2.585 ± 0.275
0.862ProMet: 0.862 ± 0.443
1.149ProAsn: 1.149 ± 0.275
1.724ProPro: 1.724 ± 0.724
0.862ProGln: 0.862 ± 0.047
1.149ProArg: 1.149 ± 0.28
2.585ProSer: 2.585 ± 0.469
2.298ProThr: 2.298 ± 0.943
3.16ProVal: 3.16 ± 0.904
0.0ProTrp: 0.0 ± 0.0
0.575ProTyr: 0.575 ± 0.228
0.0ProXaa: 0.0 ± 0.0
Gln
3.735GlnAla: 3.735 ± 1.412
0.0GlnCys: 0.0 ± 0.0
2.298GlnAsp: 2.298 ± 0.685
2.011GlnGlu: 2.011 ± 1.122
1.149GlnPhe: 1.149 ± 0.275
2.298GlnGly: 2.298 ± 0.943
0.287GlnHis: 0.287 ± 0.252
0.575GlnIle: 0.575 ± 0.228
3.16GlnLys: 3.16 ± 1.357
2.585GlnLeu: 2.585 ± 0.665
0.575GlnMet: 0.575 ± 0.406
0.862GlnAsn: 0.862 ± 0.362
0.575GlnPro: 0.575 ± 0.25
1.149GlnGln: 1.149 ± 0.28
2.585GlnArg: 2.585 ± 0.801
1.149GlnSer: 1.149 ± 0.526
1.149GlnThr: 1.149 ± 0.28
2.585GlnVal: 2.585 ± 0.448
0.0GlnTrp: 0.0 ± 0.0
0.862GlnTyr: 0.862 ± 0.362
0.0GlnXaa: 0.0 ± 0.0
Arg
3.16ArgAla: 3.16 ± 0.493
0.862ArgCys: 0.862 ± 0.35
4.022ArgAsp: 4.022 ± 0.608
6.607ArgGlu: 6.607 ± 1.076
2.298ArgPhe: 2.298 ± 0.343
4.884ArgGly: 4.884 ± 1.829
0.862ArgHis: 0.862 ± 0.435
3.735ArgIle: 3.735 ± 0.779
5.745ArgLys: 5.745 ± 2.127
6.32ArgLeu: 6.32 ± 1.876
1.724ArgMet: 1.724 ± 0.563
2.011ArgAsn: 2.011 ± 0.304
2.298ArgPro: 2.298 ± 0.313
2.011ArgGln: 2.011 ± 0.498
6.033ArgArg: 6.033 ± 1.599
2.298ArgSer: 2.298 ± 0.667
3.447ArgThr: 3.447 ± 1.192
3.447ArgVal: 3.447 ± 0.461
1.149ArgTrp: 1.149 ± 0.5
1.724ArgTyr: 1.724 ± 0.87
0.287ArgXaa: 0.287 ± 0.251
Ser
3.447SerAla: 3.447 ± 0.243
0.0SerCys: 0.0 ± 0.0
3.735SerAsp: 3.735 ± 1.614
7.182SerGlu: 7.182 ± 1.173
1.724SerPhe: 1.724 ± 0.094
5.745SerGly: 5.745 ± 1.089
0.287SerHis: 0.287 ± 0.251
2.298SerIle: 2.298 ± 0.56
4.022SerLys: 4.022 ± 0.682
5.745SerLeu: 5.745 ± 0.918
2.298SerMet: 2.298 ± 0.56
2.298SerAsn: 2.298 ± 0.23
1.149SerPro: 1.149 ± 0.157
1.149SerGln: 1.149 ± 0.455
3.16SerArg: 3.16 ± 0.39
4.596SerSer: 4.596 ± 0.783
3.735SerThr: 3.735 ± 0.673
5.458SerVal: 5.458 ± 0.471
1.724SerTrp: 1.724 ± 0.439
2.298SerTyr: 2.298 ± 0.706
0.0SerXaa: 0.0 ± 0.0
Thr
3.16ThrAla: 3.16 ± 1.035
0.287ThrCys: 0.287 ± 0.252
2.585ThrAsp: 2.585 ± 1.144
4.596ThrGlu: 4.596 ± 0.692
1.724ThrPhe: 1.724 ± 0.474
3.735ThrGly: 3.735 ± 0.738
1.149ThrHis: 1.149 ± 0.28
1.724ThrIle: 1.724 ± 0.33
2.298ThrLys: 2.298 ± 0.938
4.309ThrLeu: 4.309 ± 0.994
1.436ThrMet: 1.436 ± 0.526
1.436ThrAsn: 1.436 ± 0.53
1.724ThrPro: 1.724 ± 0.708
1.724ThrGln: 1.724 ± 0.563
3.16ThrArg: 3.16 ± 1.375
2.585ThrSer: 2.585 ± 0.661
4.022ThrThr: 4.022 ± 0.601
4.022ThrVal: 4.022 ± 0.964
1.149ThrTrp: 1.149 ± 0.5
2.011ThrTyr: 2.011 ± 0.894
0.0ThrXaa: 0.0 ± 0.0
Val
4.596ValAla: 4.596 ± 0.85
0.862ValCys: 0.862 ± 0.752
4.596ValAsp: 4.596 ± 1.12
2.873ValGlu: 2.873 ± 0.744
0.862ValPhe: 0.862 ± 0.435
5.171ValGly: 5.171 ± 0.281
1.724ValHis: 1.724 ± 0.683
4.309ValIle: 4.309 ± 0.943
2.873ValLys: 2.873 ± 0.744
7.469ValLeu: 7.469 ± 1.05
3.447ValMet: 3.447 ± 1.127
2.585ValAsn: 2.585 ± 0.809
4.596ValPro: 4.596 ± 0.414
1.724ValGln: 1.724 ± 0.312
4.596ValArg: 4.596 ± 1.419
4.884ValSer: 4.884 ± 0.175
4.309ValThr: 4.309 ± 1.238
4.884ValVal: 4.884 ± 0.83
0.575ValTrp: 0.575 ± 0.504
2.011ValTyr: 2.011 ± 0.547
0.0ValXaa: 0.0 ± 0.0
Trp
2.011TrpAla: 2.011 ± 0.481
0.862TrpCys: 0.862 ± 0.047
1.724TrpAsp: 1.724 ± 0.312
0.862TrpGlu: 0.862 ± 0.435
0.862TrpPhe: 0.862 ± 0.443
1.149TrpGly: 1.149 ± 1.003
0.575TrpHis: 0.575 ± 0.406
0.862TrpIle: 0.862 ± 0.756
1.724TrpLys: 1.724 ± 0.475
3.16TrpLeu: 3.16 ± 0.752
0.0TrpMet: 0.0 ± 0.0
0.862TrpAsn: 0.862 ± 0.35
0.575TrpPro: 0.575 ± 0.228
0.575TrpGln: 0.575 ± 0.406
1.436TrpArg: 1.436 ± 0.907
1.436TrpSer: 1.436 ± 0.228
1.436TrpThr: 1.436 ± 0.526
1.149TrpVal: 1.149 ± 0.275
0.287TrpTrp: 0.287 ± 0.251
1.149TrpTyr: 1.149 ± 0.455
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.16TyrAla: 3.16 ± 1.077
0.287TyrCys: 0.287 ± 0.203
4.596TyrAsp: 4.596 ± 0.414
2.585TyrGlu: 2.585 ± 0.908
0.862TyrPhe: 0.862 ± 0.443
2.298TyrGly: 2.298 ± 0.938
0.862TyrHis: 0.862 ± 0.435
0.862TyrIle: 0.862 ± 0.435
1.436TyrLys: 1.436 ± 0.212
3.16TyrLeu: 3.16 ± 0.212
0.575TyrMet: 0.575 ± 0.504
2.298TyrAsn: 2.298 ± 0.643
1.436TyrPro: 1.436 ± 0.36
0.287TyrGln: 0.287 ± 0.203
1.724TyrArg: 1.724 ± 0.33
2.298TyrSer: 2.298 ± 0.343
2.298TyrThr: 2.298 ± 0.207
3.16TyrVal: 3.16 ± 0.642
0.862TyrTrp: 0.862 ± 0.435
1.436TyrTyr: 1.436 ± 0.212
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.287XaaLys: 0.287 ± 0.251
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3482 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski