Amino acid dipepetide frequency for Tortoise microvirus 101

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.811AlaAla: 3.811 ± 2.564
0.0AlaCys: 0.0 ± 0.0
4.573AlaAsp: 4.573 ± 1.207
1.524AlaGlu: 1.524 ± 0.602
0.0AlaPhe: 0.0 ± 0.0
6.86AlaGly: 6.86 ± 2.385
0.762AlaHis: 0.762 ± 0.497
3.811AlaIle: 3.811 ± 1.32
4.573AlaLys: 4.573 ± 2.73
6.86AlaLeu: 6.86 ± 2.645
0.762AlaMet: 0.762 ± 0.767
6.098AlaAsn: 6.098 ± 2.721
3.049AlaPro: 3.049 ± 1.205
1.524AlaGln: 1.524 ± 1.663
6.098AlaArg: 6.098 ± 2.183
1.524AlaSer: 1.524 ± 0.954
2.287AlaThr: 2.287 ± 1.286
2.287AlaVal: 2.287 ± 1.309
0.762AlaTrp: 0.762 ± 0.497
1.524AlaTyr: 1.524 ± 0.713
0.0AlaXaa: 0.0 ± 0.0
Cys
0.762CysAla: 0.762 ± 0.497
0.0CysCys: 0.0 ± 0.0
0.762CysAsp: 0.762 ± 0.497
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.762CysGly: 0.762 ± 0.497
0.0CysHis: 0.0 ± 0.0
0.762CysIle: 0.762 ± 0.497
0.762CysLys: 0.762 ± 0.497
1.524CysLeu: 1.524 ± 0.994
0.762CysMet: 0.762 ± 0.497
0.762CysAsn: 0.762 ± 0.749
0.0CysPro: 0.0 ± 0.0
0.762CysGln: 0.762 ± 0.497
0.762CysArg: 0.762 ± 0.749
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.335AspAla: 5.335 ± 1.747
0.0AspCys: 0.0 ± 0.0
5.335AspAsp: 5.335 ± 2.324
6.098AspGlu: 6.098 ± 0.585
4.573AspPhe: 4.573 ± 2.288
1.524AspGly: 1.524 ± 0.954
2.287AspHis: 2.287 ± 0.974
6.098AspIle: 6.098 ± 2.019
6.098AspLys: 6.098 ± 2.351
3.811AspLeu: 3.811 ± 1.867
3.811AspMet: 3.811 ± 0.961
3.049AspAsn: 3.049 ± 1.181
0.762AspPro: 0.762 ± 0.497
0.0AspGln: 0.0 ± 0.0
3.049AspArg: 3.049 ± 0.594
2.287AspSer: 2.287 ± 1.379
3.049AspThr: 3.049 ± 1.205
3.049AspVal: 3.049 ± 1.137
1.524AspTrp: 1.524 ± 0.602
4.573AspTyr: 4.573 ± 1.39
0.0AspXaa: 0.0 ± 0.0
Glu
5.335GluAla: 5.335 ± 3.872
0.0GluCys: 0.0 ± 0.0
0.762GluAsp: 0.762 ± 0.767
0.762GluGlu: 0.762 ± 1.515
3.811GluPhe: 3.811 ± 1.629
3.049GluGly: 3.049 ± 1.137
1.524GluHis: 1.524 ± 0.713
4.573GluIle: 4.573 ± 0.961
3.049GluLys: 3.049 ± 1.205
3.811GluLeu: 3.811 ± 0.966
3.049GluMet: 3.049 ± 1.918
3.049GluAsn: 3.049 ± 2.03
3.049GluPro: 3.049 ± 4.341
4.573GluGln: 4.573 ± 2.572
6.86GluArg: 6.86 ± 2.191
4.573GluSer: 4.573 ± 4.327
1.524GluThr: 1.524 ± 0.994
3.049GluVal: 3.049 ± 0.594
2.287GluTrp: 2.287 ± 2.247
5.335GluTyr: 5.335 ± 1.108
0.0GluXaa: 0.0 ± 0.0
Phe
3.049PheAla: 3.049 ± 1.331
0.0PheCys: 0.0 ± 0.0
6.098PheAsp: 6.098 ± 2.363
3.049PheGlu: 3.049 ± 1.564
2.287PhePhe: 2.287 ± 1.491
5.335PheGly: 5.335 ± 2.767
0.762PheHis: 0.762 ± 0.497
2.287PheIle: 2.287 ± 0.62
3.049PheLys: 3.049 ± 1.181
2.287PheLeu: 2.287 ± 0.795
2.287PheMet: 2.287 ± 1.491
2.287PheAsn: 2.287 ± 1.375
1.524PhePro: 1.524 ± 0.994
0.0PheGln: 0.0 ± 0.0
3.811PheArg: 3.811 ± 1.629
5.335PheSer: 5.335 ± 1.42
3.049PheThr: 3.049 ± 1.564
3.811PheVal: 3.811 ± 2.485
0.762PheTrp: 0.762 ± 0.497
1.524PheTyr: 1.524 ± 0.994
0.0PheXaa: 0.0 ± 0.0
Gly
3.049GlyAla: 3.049 ± 1.181
0.762GlyCys: 0.762 ± 0.497
6.098GlyAsp: 6.098 ± 2.274
6.098GlyGlu: 6.098 ± 2.131
2.287GlyPhe: 2.287 ± 1.491
3.049GlyGly: 3.049 ± 1.181
0.0GlyHis: 0.0 ± 0.0
5.335GlyIle: 5.335 ± 1.486
0.762GlyLys: 0.762 ± 0.497
5.335GlyLeu: 5.335 ± 0.74
2.287GlyMet: 2.287 ± 1.491
0.0GlyAsn: 0.0 ± 0.0
0.0GlyPro: 0.0 ± 0.0
1.524GlyGln: 1.524 ± 0.602
1.524GlyArg: 1.524 ± 0.713
5.335GlySer: 5.335 ± 1.807
5.335GlyThr: 5.335 ± 1.42
3.811GlyVal: 3.811 ± 1.82
0.0GlyTrp: 0.0 ± 0.0
3.049GlyTyr: 3.049 ± 1.181
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.762HisAsp: 0.762 ± 0.497
0.762HisGlu: 0.762 ± 0.497
2.287HisPhe: 2.287 ± 1.491
3.049HisGly: 3.049 ± 1.373
1.524HisHis: 1.524 ± 0.994
0.0HisIle: 0.0 ± 0.0
0.762HisLys: 0.762 ± 0.767
3.049HisLeu: 3.049 ± 2.097
1.524HisMet: 1.524 ± 0.994
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.762HisGln: 0.762 ± 0.767
0.762HisArg: 0.762 ± 0.749
0.0HisSer: 0.0 ± 0.0
2.287HisThr: 2.287 ± 1.422
0.762HisVal: 0.762 ± 0.749
0.762HisTrp: 0.762 ± 0.497
0.762HisTyr: 0.762 ± 0.749
0.0HisXaa: 0.0 ± 0.0
Ile
1.524IleAla: 1.524 ± 1.533
0.0IleCys: 0.0 ± 0.0
4.573IleAsp: 4.573 ± 1.66
3.049IleGlu: 3.049 ± 1.205
4.573IlePhe: 4.573 ± 2.099
4.573IleGly: 4.573 ± 1.24
1.524IleHis: 1.524 ± 0.994
0.762IleIle: 0.762 ± 0.497
2.287IleLys: 2.287 ± 0.795
3.811IleLeu: 3.811 ± 1.914
1.524IleMet: 1.524 ± 0.994
3.049IleAsn: 3.049 ± 1.331
4.573IlePro: 4.573 ± 1.59
3.049IleGln: 3.049 ± 2.097
4.573IleArg: 4.573 ± 3.383
3.811IleSer: 3.811 ± 1.629
3.811IleThr: 3.811 ± 0.961
1.524IleVal: 1.524 ± 0.954
0.0IleTrp: 0.0 ± 0.0
1.524IleTyr: 1.524 ± 0.994
0.0IleXaa: 0.0 ± 0.0
Lys
2.287LysAla: 2.287 ± 0.795
0.0LysCys: 0.0 ± 0.0
4.573LysAsp: 4.573 ± 2.434
5.335LysGlu: 5.335 ± 3.412
3.811LysPhe: 3.811 ± 0.904
1.524LysGly: 1.524 ± 0.954
1.524LysHis: 1.524 ± 0.602
2.287LysIle: 2.287 ± 0.974
5.335LysLys: 5.335 ± 3.18
7.622LysLeu: 7.622 ± 1.932
2.287LysMet: 2.287 ± 1.022
3.811LysAsn: 3.811 ± 0.966
3.811LysPro: 3.811 ± 1.094
0.762LysGln: 0.762 ± 0.497
4.573LysArg: 4.573 ± 1.779
3.811LysSer: 3.811 ± 1.633
1.524LysThr: 1.524 ± 0.713
3.811LysVal: 3.811 ± 0.961
0.0LysTrp: 0.0 ± 0.0
1.524LysTyr: 1.524 ± 0.954
0.0LysXaa: 0.0 ± 0.0
Leu
5.335LeuAla: 5.335 ± 2.401
0.762LeuCys: 0.762 ± 0.749
7.622LeuAsp: 7.622 ± 1.932
4.573LeuGlu: 4.573 ± 2.658
3.049LeuPhe: 3.049 ± 1.331
3.049LeuGly: 3.049 ± 1.205
0.762LeuHis: 0.762 ± 0.497
2.287LeuIle: 2.287 ± 0.62
5.335LeuLys: 5.335 ± 2.737
3.049LeuLeu: 3.049 ± 1.988
3.811LeuMet: 3.811 ± 1.033
6.098LeuAsn: 6.098 ± 2.409
6.098LeuPro: 6.098 ± 1.312
7.622LeuGln: 7.622 ± 2.808
4.573LeuArg: 4.573 ± 1.332
7.622LeuSer: 7.622 ± 2.329
2.287LeuThr: 2.287 ± 0.62
3.049LeuVal: 3.049 ± 1.236
0.762LeuTrp: 0.762 ± 0.497
2.287LeuTyr: 2.287 ± 1.491
0.0LeuXaa: 0.0 ± 0.0
Met
3.811MetAla: 3.811 ± 2.228
1.524MetCys: 1.524 ± 0.994
3.049MetAsp: 3.049 ± 1.205
0.0MetGlu: 0.0 ± 0.0
0.762MetPhe: 0.762 ± 0.749
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.762MetIle: 0.762 ± 0.767
6.098MetLys: 6.098 ± 1.78
3.811MetLeu: 3.811 ± 0.904
0.0MetMet: 0.0 ± 0.0
2.287MetAsn: 2.287 ± 1.379
3.049MetPro: 3.049 ± 1.331
2.287MetGln: 2.287 ± 1.491
2.287MetArg: 2.287 ± 1.422
4.573MetSer: 4.573 ± 1.166
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.762MetTrp: 0.762 ± 0.767
0.762MetTyr: 0.762 ± 0.497
0.0MetXaa: 0.0 ± 0.0
Asn
3.049AsnAla: 3.049 ± 0.594
2.287AsnCys: 2.287 ± 1.491
1.524AsnAsp: 1.524 ± 0.602
5.335AsnGlu: 5.335 ± 1.486
2.287AsnPhe: 2.287 ± 1.309
2.287AsnGly: 2.287 ± 0.974
2.287AsnHis: 2.287 ± 0.974
1.524AsnIle: 1.524 ± 0.994
3.049AsnLys: 3.049 ± 1.205
7.622AsnLeu: 7.622 ± 2.737
0.0AsnMet: 0.0 ± 0.0
3.811AsnAsn: 3.811 ± 1.363
1.524AsnPro: 1.524 ± 1.622
3.811AsnGln: 3.811 ± 0.961
6.86AsnArg: 6.86 ± 3.1
5.335AsnSer: 5.335 ± 1.885
1.524AsnThr: 1.524 ± 1.533
3.049AsnVal: 3.049 ± 2.03
0.0AsnTrp: 0.0 ± 0.0
3.049AsnTyr: 3.049 ± 2.218
0.0AsnXaa: 0.0 ± 0.0
Pro
1.524ProAla: 1.524 ± 0.713
0.0ProCys: 0.0 ± 0.0
2.287ProAsp: 2.287 ± 1.379
3.049ProGlu: 3.049 ± 2.03
5.335ProPhe: 5.335 ± 1.997
3.049ProGly: 3.049 ± 1.373
0.762ProHis: 0.762 ± 0.749
3.049ProIle: 3.049 ± 2.851
2.287ProLys: 2.287 ± 1.379
4.573ProLeu: 4.573 ± 1.207
0.762ProMet: 0.762 ± 1.515
0.762ProAsn: 0.762 ± 1.515
3.049ProPro: 3.049 ± 1.137
1.524ProGln: 1.524 ± 1.361
3.049ProArg: 3.049 ± 1.236
0.0ProSer: 0.0 ± 0.0
1.524ProThr: 1.524 ± 0.994
4.573ProVal: 4.573 ± 1.117
0.762ProTrp: 0.762 ± 0.497
1.524ProTyr: 1.524 ± 0.602
0.0ProXaa: 0.0 ± 0.0
Gln
3.811GlnAla: 3.811 ± 1.563
1.524GlnCys: 1.524 ± 0.713
2.287GlnAsp: 2.287 ± 0.974
3.049GlnGlu: 3.049 ± 1.373
3.049GlnPhe: 3.049 ± 1.988
0.0GlnGly: 0.0 ± 0.0
0.762GlnHis: 0.762 ± 0.767
2.287GlnIle: 2.287 ± 1.286
2.287GlnLys: 2.287 ± 1.286
3.811GlnLeu: 3.811 ± 2.228
1.524GlnMet: 1.524 ± 0.954
3.811GlnAsn: 3.811 ± 1.914
2.287GlnPro: 2.287 ± 1.422
3.049GlnGln: 3.049 ± 1.181
2.287GlnArg: 2.287 ± 1.379
0.762GlnSer: 0.762 ± 0.749
3.811GlnThr: 3.811 ± 2.558
1.524GlnVal: 1.524 ± 0.994
0.0GlnTrp: 0.0 ± 0.0
1.524GlnTyr: 1.524 ± 1.533
0.0GlnXaa: 0.0 ± 0.0
Arg
6.86ArgAla: 6.86 ± 0.506
1.524ArgCys: 1.524 ± 0.994
2.287ArgAsp: 2.287 ± 0.974
5.335ArgGlu: 5.335 ± 2.234
2.287ArgPhe: 2.287 ± 0.62
5.335ArgGly: 5.335 ± 1.187
0.0ArgHis: 0.0 ± 0.0
3.049ArgIle: 3.049 ± 1.988
3.811ArgLys: 3.811 ± 2.934
3.811ArgLeu: 3.811 ± 1.53
2.287ArgMet: 2.287 ± 2.088
3.049ArgAsn: 3.049 ± 1.908
0.762ArgPro: 0.762 ± 0.749
3.049ArgGln: 3.049 ± 2.722
3.049ArgArg: 3.049 ± 2.03
5.335ArgSer: 5.335 ± 2.401
3.049ArgThr: 3.049 ± 1.181
3.811ArgVal: 3.811 ± 1.42
0.0ArgTrp: 0.0 ± 0.0
7.622ArgTyr: 7.622 ± 1.695
0.0ArgXaa: 0.0 ± 0.0
Ser
2.287SerAla: 2.287 ± 0.62
0.0SerCys: 0.0 ± 0.0
4.573SerAsp: 4.573 ± 2.844
5.335SerGlu: 5.335 ± 2.605
3.049SerPhe: 3.049 ± 1.181
3.811SerGly: 3.811 ± 0.966
0.762SerHis: 0.762 ± 0.497
6.098SerIle: 6.098 ± 1.189
3.049SerLys: 3.049 ± 2.097
6.86SerLeu: 6.86 ± 2.759
1.524SerMet: 1.524 ± 0.994
4.573SerAsn: 4.573 ± 1.896
1.524SerPro: 1.524 ± 0.602
2.287SerGln: 2.287 ± 2.034
3.049SerArg: 3.049 ± 0.594
6.098SerSer: 6.098 ± 1.463
4.573SerThr: 4.573 ± 1.117
3.811SerVal: 3.811 ± 3.055
0.0SerTrp: 0.0 ± 0.0
3.811SerTyr: 3.811 ± 0.966
0.0SerXaa: 0.0 ± 0.0
Thr
2.287ThrAla: 2.287 ± 1.286
0.0ThrCys: 0.0 ± 0.0
2.287ThrAsp: 2.287 ± 1.422
0.762ThrGlu: 0.762 ± 0.767
2.287ThrPhe: 2.287 ± 0.795
2.287ThrGly: 2.287 ± 1.491
0.0ThrHis: 0.0 ± 0.0
2.287ThrIle: 2.287 ± 1.309
4.573ThrLys: 4.573 ± 1.332
2.287ThrLeu: 2.287 ± 0.62
1.524ThrMet: 1.524 ± 0.994
3.049ThrAsn: 3.049 ± 1.198
4.573ThrPro: 4.573 ± 2.844
2.287ThrGln: 2.287 ± 0.795
2.287ThrArg: 2.287 ± 0.62
5.335ThrSer: 5.335 ± 2.579
0.762ThrThr: 0.762 ± 0.497
3.049ThrVal: 3.049 ± 1.331
0.762ThrTrp: 0.762 ± 0.767
5.335ThrTyr: 5.335 ± 2.598
0.0ThrXaa: 0.0 ± 0.0
Val
3.049ValAla: 3.049 ± 1.137
0.0ValCys: 0.0 ± 0.0
2.287ValAsp: 2.287 ± 0.62
7.622ValGlu: 7.622 ± 5.521
2.287ValPhe: 2.287 ± 0.974
2.287ValGly: 2.287 ± 0.974
0.762ValHis: 0.762 ± 1.515
2.287ValIle: 2.287 ± 1.309
1.524ValLys: 1.524 ± 0.713
1.524ValLeu: 1.524 ± 0.602
3.049ValMet: 3.049 ± 1.094
4.573ValAsn: 4.573 ± 1.166
3.811ValPro: 3.811 ± 1.168
0.762ValGln: 0.762 ± 0.497
2.287ValArg: 2.287 ± 0.795
1.524ValSer: 1.524 ± 0.602
3.811ValThr: 3.811 ± 2.058
1.524ValVal: 1.524 ± 0.954
0.0ValTrp: 0.0 ± 0.0
4.573ValTyr: 4.573 ± 2.75
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.762TrpGlu: 0.762 ± 0.497
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.762TrpHis: 0.762 ± 0.497
0.762TrpIle: 0.762 ± 0.767
0.762TrpLys: 0.762 ± 0.497
0.762TrpLeu: 0.762 ± 0.749
0.762TrpMet: 0.762 ± 0.497
0.762TrpAsn: 0.762 ± 0.497
0.0TrpPro: 0.0 ± 0.0
1.524TrpGln: 1.524 ± 0.954
0.762TrpArg: 0.762 ± 0.497
0.762TrpSer: 0.762 ± 0.767
0.762TrpThr: 0.762 ± 0.497
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.762TrpTyr: 0.762 ± 0.749
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.524TyrAla: 1.524 ± 0.602
0.0TyrCys: 0.0 ± 0.0
4.573TyrAsp: 4.573 ± 1.646
1.524TyrGlu: 1.524 ± 1.361
4.573TyrPhe: 4.573 ± 2.983
3.811TyrGly: 3.811 ± 1.094
3.049TyrHis: 3.049 ± 2.997
3.811TyrIle: 3.811 ± 1.094
1.524TyrLys: 1.524 ± 0.954
3.811TyrLeu: 3.811 ± 1.914
1.524TyrMet: 1.524 ± 0.954
5.335TyrAsn: 5.335 ± 1.108
0.0TyrPro: 0.0 ± 0.0
2.287TyrGln: 2.287 ± 0.795
3.811TyrArg: 3.811 ± 1.094
3.049TyrSer: 3.049 ± 1.181
3.049TyrThr: 3.049 ± 1.137
3.049TyrVal: 3.049 ± 1.236
0.762TyrTrp: 0.762 ± 0.497
5.335TyrTyr: 5.335 ± 3.18
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1313 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski