Amino acid dipepetide frequency for Papaya meleira virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.706AlaAla: 0.706 ± 0.628
0.0AlaCys: 0.0 ± 0.0
1.411AlaAsp: 1.411 ± 0.451
0.706AlaGlu: 0.706 ± 0.462
2.117AlaPhe: 2.117 ± 2.284
2.117AlaGly: 2.117 ± 0.891
1.764AlaHis: 1.764 ± 2.247
2.47AlaIle: 2.47 ± 0.691
2.47AlaLys: 2.47 ± 0.691
2.47AlaLeu: 2.47 ± 1.924
0.706AlaMet: 0.706 ± 0.38
3.529AlaAsn: 3.529 ± 1.814
1.764AlaPro: 1.764 ± 1.154
2.117AlaGln: 2.117 ± 0.898
2.117AlaArg: 2.117 ± 0.898
4.234AlaSer: 4.234 ± 0.996
2.117AlaThr: 2.117 ± 2.284
1.411AlaVal: 1.411 ± 0.329
0.0AlaTrp: 0.0 ± 0.0
1.764AlaTyr: 1.764 ± 0.353
0.0AlaXaa: 0.0 ± 0.0
Cys
0.353CysAla: 0.353 ± 0.231
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.411CysGlu: 1.411 ± 0.753
0.353CysPhe: 0.353 ± 0.231
0.353CysGly: 0.353 ± 0.231
0.706CysHis: 0.706 ± 2.276
0.353CysIle: 0.353 ± 0.231
0.353CysLys: 0.353 ± 0.314
1.411CysLeu: 1.411 ± 0.329
0.0CysMet: 0.0 ± 0.0
1.764CysAsn: 1.764 ± 1.065
0.353CysPro: 0.353 ± 0.314
0.353CysGln: 0.353 ± 0.314
1.059CysArg: 1.059 ± 0.249
0.706CysSer: 0.706 ± 0.462
0.706CysThr: 0.706 ± 0.165
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.764CysTyr: 1.764 ± 2.056
0.0CysXaa: 0.0 ± 0.0
Asp
1.059AspAla: 1.059 ± 0.249
0.353AspCys: 0.353 ± 0.231
2.823AspAsp: 2.823 ± 0.658
1.764AspGlu: 1.764 ± 0.353
2.47AspPhe: 2.47 ± 1.197
2.47AspGly: 2.47 ± 0.691
0.0AspHis: 0.0 ± 0.0
4.94AspIle: 4.94 ± 2.325
2.47AspLys: 2.47 ± 0.492
5.646AspLeu: 5.646 ± 2.175
1.059AspMet: 1.059 ± 0.445
4.94AspAsn: 4.94 ± 1.382
2.823AspPro: 2.823 ± 1.036
0.706AspGln: 0.706 ± 0.628
1.411AspArg: 1.411 ± 0.923
4.234AspSer: 4.234 ± 0.996
2.117AspThr: 2.117 ± 0.498
2.823AspVal: 2.823 ± 0.589
0.0AspTrp: 0.0 ± 0.0
2.47AspTyr: 2.47 ± 0.691
0.0AspXaa: 0.0 ± 0.0
Glu
3.176GluAla: 3.176 ± 1.921
0.353GluCys: 0.353 ± 0.231
1.764GluAsp: 1.764 ± 1.065
3.881GluGlu: 3.881 ± 0.799
2.823GluPhe: 2.823 ± 0.658
3.881GluGly: 3.881 ± 1.569
0.0GluHis: 0.0 ± 0.0
5.293GluIle: 5.293 ± 1.391
3.881GluLys: 3.881 ± 0.799
6.351GluLeu: 6.351 ± 1.874
0.706GluMet: 0.706 ± 0.462
2.47GluAsn: 2.47 ± 0.492
1.764GluPro: 1.764 ± 0.672
0.706GluGln: 0.706 ± 0.462
2.117GluArg: 2.117 ± 2.205
2.823GluSer: 2.823 ± 1.506
3.176GluThr: 3.176 ± 1.121
1.411GluVal: 1.411 ± 0.923
1.059GluTrp: 1.059 ± 0.249
3.881GluTyr: 3.881 ± 0.832
0.0GluXaa: 0.0 ± 0.0
Phe
0.706PheAla: 0.706 ± 0.165
0.706PheCys: 0.706 ± 2.276
1.764PheAsp: 1.764 ± 0.353
2.117PheGlu: 2.117 ± 4.427
2.117PhePhe: 2.117 ± 1.377
2.47PheGly: 2.47 ± 0.492
0.353PheHis: 0.353 ± 0.231
7.057PheIle: 7.057 ± 1.448
4.234PheLys: 4.234 ± 1.782
4.234PheLeu: 4.234 ± 1.986
0.706PheMet: 0.706 ± 0.462
5.646PheAsn: 5.646 ± 2.073
2.823PhePro: 2.823 ± 0.589
1.411PheGln: 1.411 ± 0.329
1.411PheArg: 1.411 ± 0.329
7.41PheSer: 7.41 ± 1.642
2.117PheThr: 2.117 ± 1.385
1.411PheVal: 1.411 ± 2.128
1.059PheTrp: 1.059 ± 0.445
1.411PheTyr: 1.411 ± 0.329
0.0PheXaa: 0.0 ± 0.0
Gly
2.823GlyAla: 2.823 ± 0.658
1.411GlyCys: 1.411 ± 1.257
2.47GlyAsp: 2.47 ± 0.749
3.176GlyGlu: 3.176 ± 0.907
2.823GlyPhe: 2.823 ± 1.916
3.881GlyGly: 3.881 ± 1.481
1.059GlyHis: 1.059 ± 0.692
4.234GlyIle: 4.234 ± 0.988
3.176GlyLys: 3.176 ± 0.643
5.293GlyLeu: 5.293 ± 1.245
1.411GlyMet: 1.411 ± 2.128
2.47GlyAsn: 2.47 ± 1.616
2.117GlyPro: 2.117 ± 0.898
2.47GlyGln: 2.47 ± 0.691
4.234GlyArg: 4.234 ± 3.979
2.117GlySer: 2.117 ± 0.498
2.117GlyThr: 2.117 ± 0.498
2.117GlyVal: 2.117 ± 0.498
1.059GlyTrp: 1.059 ± 0.445
1.059GlyTyr: 1.059 ± 0.445
0.0GlyXaa: 0.0 ± 0.0
His
1.059HisAla: 1.059 ± 0.692
1.059HisCys: 1.059 ± 0.249
0.706HisAsp: 0.706 ± 0.165
0.706HisGlu: 0.706 ± 0.462
0.706HisPhe: 0.706 ± 4.664
0.353HisGly: 0.353 ± 0.314
0.353HisHis: 0.353 ± 0.231
1.411HisIle: 1.411 ± 0.451
0.706HisLys: 0.706 ± 0.165
2.117HisLeu: 2.117 ± 0.898
0.353HisMet: 0.353 ± 0.231
2.117HisAsn: 2.117 ± 1.385
1.059HisPro: 1.059 ± 0.249
0.706HisGln: 0.706 ± 0.165
1.411HisArg: 1.411 ± 2.128
1.764HisSer: 1.764 ± 0.672
0.706HisThr: 0.706 ± 0.462
0.706HisVal: 0.706 ± 0.462
0.706HisTrp: 0.706 ± 0.165
1.764HisTyr: 1.764 ± 0.594
0.0HisXaa: 0.0 ± 0.0
Ile
0.353IleAla: 0.353 ± 0.314
1.411IleCys: 1.411 ± 0.753
3.529IleAsp: 3.529 ± 0.823
3.176IleGlu: 3.176 ± 1.336
1.411IlePhe: 1.411 ± 0.753
4.587IleGly: 4.587 ± 2.543
2.117IleHis: 2.117 ± 0.898
4.94IleIle: 4.94 ± 1.152
6.704IleLys: 6.704 ± 1.443
10.233IleLeu: 10.233 ± 3.821
0.353IleMet: 0.353 ± 1.571
9.174IleAsn: 9.174 ± 1.823
8.116IlePro: 8.116 ± 2.492
2.117IleGln: 2.117 ± 1.385
4.234IleArg: 4.234 ± 1.341
10.586IleSer: 10.586 ± 2.77
4.94IleThr: 4.94 ± 1.497
2.823IleVal: 2.823 ± 0.658
1.059IleTrp: 1.059 ± 0.445
3.529IleTyr: 3.529 ± 1.187
0.0IleXaa: 0.0 ± 0.0
Lys
3.176LysAla: 3.176 ± 0.643
0.353LysCys: 0.353 ± 0.314
5.646LysAsp: 5.646 ± 1.293
4.234LysGlu: 4.234 ± 0.988
4.234LysPhe: 4.234 ± 1.341
4.94LysGly: 4.94 ± 0.984
0.706LysHis: 0.706 ± 0.165
5.646LysIle: 5.646 ± 1.317
4.234LysLys: 4.234 ± 0.996
5.646LysLeu: 5.646 ± 1.655
1.411LysMet: 1.411 ± 0.753
4.234LysAsn: 4.234 ± 1.341
1.764LysPro: 1.764 ± 0.353
1.411LysGln: 1.411 ± 0.329
2.47LysArg: 2.47 ± 0.691
3.881LysSer: 3.881 ± 0.799
2.47LysThr: 2.47 ± 0.749
7.057LysVal: 7.057 ± 2.255
1.059LysTrp: 1.059 ± 0.445
3.176LysTyr: 3.176 ± 1.336
0.0LysXaa: 0.0 ± 0.0
Leu
5.293LeuAla: 5.293 ± 2.047
0.706LeuCys: 0.706 ± 0.165
4.234LeuAsp: 4.234 ± 0.988
6.351LeuGlu: 6.351 ± 2.673
6.351LeuPhe: 6.351 ± 3.146
5.293LeuGly: 5.293 ± 1.391
1.059LeuHis: 1.059 ± 2.266
9.174LeuIle: 9.174 ± 3.98
5.646LeuLys: 5.646 ± 1.133
9.174LeuLeu: 9.174 ± 3.918
1.764LeuMet: 1.764 ± 0.353
9.174LeuAsn: 9.174 ± 3.599
8.116LeuPro: 8.116 ± 3.229
3.881LeuGln: 3.881 ± 0.832
3.881LeuArg: 3.881 ± 0.799
9.527LeuSer: 9.527 ± 5.67
4.94LeuThr: 4.94 ± 3.988
2.823LeuVal: 2.823 ± 1.846
1.059LeuTrp: 1.059 ± 0.249
4.234LeuTyr: 4.234 ± 1.341
0.0LeuXaa: 0.0 ± 0.0
Met
0.706MetAla: 0.706 ± 0.165
0.353MetCys: 0.353 ± 0.231
0.706MetAsp: 0.706 ± 0.462
0.0MetGlu: 0.0 ± 0.0
1.411MetPhe: 1.411 ± 0.451
0.353MetGly: 0.353 ± 0.314
0.0MetHis: 0.0 ± 0.0
2.47MetIle: 2.47 ± 0.492
1.411MetLys: 1.411 ± 0.329
0.706MetLeu: 0.706 ± 0.165
0.0MetMet: 0.0 ± 0.0
0.706MetAsn: 0.706 ± 0.462
0.353MetPro: 0.353 ± 0.231
0.706MetGln: 0.706 ± 0.165
1.764MetArg: 1.764 ± 0.353
0.353MetSer: 0.353 ± 0.231
1.764MetThr: 1.764 ± 2.088
1.411MetVal: 1.411 ± 2.233
0.0MetTrp: 0.0 ± 0.0
1.059MetTyr: 1.059 ± 0.445
0.0MetXaa: 0.0 ± 0.0
Asn
1.411AsnAla: 1.411 ± 0.451
1.764AsnCys: 1.764 ± 2.156
1.764AsnAsp: 1.764 ± 0.672
3.529AsnGlu: 3.529 ± 1.344
5.999AsnPhe: 5.999 ± 1.376
2.117AsnGly: 2.117 ± 2.073
3.529AsnHis: 3.529 ± 1.814
6.351AsnIle: 6.351 ± 2.673
7.41AsnLys: 7.41 ± 2.666
9.174AsnLeu: 9.174 ± 3.259
0.353AsnMet: 0.353 ± 0.209
7.763AsnAsn: 7.763 ± 2.527
2.823AsnPro: 2.823 ± 0.589
3.529AsnGln: 3.529 ± 1.344
3.176AsnArg: 3.176 ± 4.173
8.469AsnSer: 8.469 ± 0.739
5.646AsnThr: 5.646 ± 1.317
4.587AsnVal: 4.587 ± 1.182
1.411AsnTrp: 1.411 ± 0.923
2.117AsnTyr: 2.117 ± 0.891
0.0AsnXaa: 0.0 ± 0.0
Pro
2.47ProAla: 2.47 ± 2.344
0.353ProCys: 0.353 ± 0.231
2.47ProAsp: 2.47 ± 2.053
2.117ProGlu: 2.117 ± 1.385
1.411ProPhe: 1.411 ± 0.451
2.823ProGly: 2.823 ± 0.902
0.353ProHis: 0.353 ± 0.231
5.646ProIle: 5.646 ± 1.327
5.293ProLys: 5.293 ± 2.016
7.057ProLeu: 7.057 ± 1.133
1.059ProMet: 1.059 ± 0.692
2.117ProAsn: 2.117 ± 0.494
1.764ProPro: 1.764 ± 0.353
1.059ProGln: 1.059 ± 0.692
1.764ProArg: 1.764 ± 0.672
5.646ProSer: 5.646 ± 1.777
1.764ProThr: 1.764 ± 0.672
4.94ProVal: 4.94 ± 1.382
0.706ProTrp: 0.706 ± 0.462
1.764ProTyr: 1.764 ± 0.672
0.0ProXaa: 0.0 ± 0.0
Gln
0.706GlnAla: 0.706 ± 0.462
0.353GlnCys: 0.353 ± 0.231
2.823GlnAsp: 2.823 ± 1.355
2.823GlnGlu: 2.823 ± 0.589
1.059GlnPhe: 1.059 ± 0.692
1.764GlnGly: 1.764 ± 0.353
0.353GlnHis: 0.353 ± 0.314
1.059GlnIle: 1.059 ± 0.249
1.764GlnLys: 1.764 ± 0.672
3.529GlnLeu: 3.529 ± 0.823
0.353GlnMet: 0.353 ± 0.231
1.411GlnAsn: 1.411 ± 0.753
1.764GlnPro: 1.764 ± 0.672
0.0GlnGln: 0.0 ± 0.0
2.117GlnArg: 2.117 ± 0.898
2.823GlnSer: 2.823 ± 1.355
1.411GlnThr: 1.411 ± 0.329
3.529GlnVal: 3.529 ± 0.823
0.0GlnTrp: 0.0 ± 0.0
1.059GlnTyr: 1.059 ± 0.692
0.0GlnXaa: 0.0 ± 0.0
Arg
2.823ArgAla: 2.823 ± 1.915
0.706ArgCys: 0.706 ± 0.165
2.117ArgAsp: 2.117 ± 1.385
3.529ArgGlu: 3.529 ± 0.823
2.823ArgPhe: 2.823 ± 0.589
2.47ArgGly: 2.47 ± 2.053
0.353ArgHis: 0.353 ± 0.231
2.47ArgIle: 2.47 ± 1.126
2.117ArgLys: 2.117 ± 0.898
7.057ArgLeu: 7.057 ± 5.845
0.706ArgMet: 0.706 ± 0.165
3.529ArgAsn: 3.529 ± 0.936
1.764ArgPro: 1.764 ± 2.088
1.059ArgGln: 1.059 ± 0.943
2.47ArgArg: 2.47 ± 1.126
3.529ArgSer: 3.529 ± 2.048
1.764ArgThr: 1.764 ± 1.154
3.881ArgVal: 3.881 ± 0.799
0.353ArgTrp: 0.353 ± 0.231
1.059ArgTyr: 1.059 ± 0.249
0.0ArgXaa: 0.0 ± 0.0
Ser
2.47SerAla: 2.47 ± 0.691
1.059SerCys: 1.059 ± 0.249
3.881SerAsp: 3.881 ± 0.832
4.234SerGlu: 4.234 ± 0.841
4.587SerPhe: 4.587 ± 3.895
4.94SerGly: 4.94 ± 0.984
2.823SerHis: 2.823 ± 0.589
6.704SerIle: 6.704 ± 1.331
5.293SerLys: 5.293 ± 1.738
9.527SerLeu: 9.527 ± 3.752
0.706SerMet: 0.706 ± 0.165
6.704SerAsn: 6.704 ± 6.458
5.999SerPro: 5.999 ± 4.034
3.881SerGln: 3.881 ± 1.14
2.823SerArg: 2.823 ± 0.902
8.469SerSer: 8.469 ± 1.585
3.881SerThr: 3.881 ± 1.14
6.351SerVal: 6.351 ± 1.291
1.764SerTrp: 1.764 ± 0.594
3.176SerTyr: 3.176 ± 0.643
0.0SerXaa: 0.0 ± 0.0
Thr
2.117ThrAla: 2.117 ± 0.898
0.353ThrCys: 0.353 ± 0.231
2.117ThrAsp: 2.117 ± 0.494
2.117ThrGlu: 2.117 ± 0.898
2.47ThrPhe: 2.47 ± 1.197
2.117ThrGly: 2.117 ± 2.284
2.117ThrHis: 2.117 ± 0.898
5.999ThrIle: 5.999 ± 1.626
5.646ThrLys: 5.646 ± 2.073
3.529ThrLeu: 3.529 ± 1.703
0.706ThrMet: 0.706 ± 0.462
4.234ThrAsn: 4.234 ± 2.1
2.823ThrPro: 2.823 ± 1.846
0.706ThrGln: 0.706 ± 0.165
2.117ThrArg: 2.117 ± 1.983
4.234ThrSer: 4.234 ± 1.341
2.47ThrThr: 2.47 ± 0.691
1.764ThrVal: 1.764 ± 0.672
0.353ThrTrp: 0.353 ± 0.314
1.764ThrTyr: 1.764 ± 0.672
0.0ThrXaa: 0.0 ± 0.0
Val
3.176ValAla: 3.176 ± 1.584
0.353ValCys: 0.353 ± 0.231
1.411ValAsp: 1.411 ± 0.451
2.823ValGlu: 2.823 ± 1.915
3.176ValPhe: 3.176 ± 0.643
1.764ValGly: 1.764 ± 1.154
2.117ValHis: 2.117 ± 0.891
4.94ValIle: 4.94 ± 1.382
3.881ValLys: 3.881 ± 1.067
3.881ValLeu: 3.881 ± 1.067
2.823ValMet: 2.823 ± 0.589
5.293ValAsn: 5.293 ± 1.119
2.823ValPro: 2.823 ± 1.355
2.117ValGln: 2.117 ± 0.898
2.823ValArg: 2.823 ± 0.902
3.176ValSer: 3.176 ± 1.121
2.823ValThr: 2.823 ± 0.902
2.47ValVal: 2.47 ± 0.749
0.353ValTrp: 0.353 ± 0.231
1.764ValTyr: 1.764 ± 2.247
0.0ValXaa: 0.0 ± 0.0
Trp
0.353TrpAla: 0.353 ± 0.231
0.0TrpCys: 0.0 ± 0.0
0.706TrpAsp: 0.706 ± 0.462
0.353TrpGlu: 0.353 ± 0.231
0.706TrpPhe: 0.706 ± 0.628
0.353TrpGly: 0.353 ± 0.231
0.0TrpHis: 0.0 ± 0.0
1.411TrpIle: 1.411 ± 1.257
0.0TrpLys: 0.0 ± 0.0
1.764TrpLeu: 1.764 ± 0.672
0.353TrpMet: 0.353 ± 0.231
1.059TrpAsn: 1.059 ± 0.943
1.059TrpPro: 1.059 ± 0.692
1.059TrpGln: 1.059 ± 0.692
0.706TrpArg: 0.706 ± 0.165
1.411TrpSer: 1.411 ± 0.753
0.353TrpThr: 0.353 ± 0.231
0.353TrpVal: 0.353 ± 0.314
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.411TyrAla: 1.411 ± 0.451
0.353TyrCys: 0.353 ± 0.314
4.234TyrAsp: 4.234 ± 0.988
2.47TyrGlu: 2.47 ± 1.126
2.117TyrPhe: 2.117 ± 0.498
2.47TyrGly: 2.47 ± 0.749
0.706TyrHis: 0.706 ± 0.462
2.823TyrIle: 2.823 ± 2.427
1.059TyrLys: 1.059 ± 0.445
3.881TyrLeu: 3.881 ± 1.678
0.353TyrMet: 0.353 ± 0.231
4.587TyrAsn: 4.587 ± 0.939
0.706TyrPro: 0.706 ± 0.165
0.706TyrGln: 0.706 ± 0.165
2.47TyrArg: 2.47 ± 1.126
3.881TyrSer: 3.881 ± 0.799
2.47TyrThr: 2.47 ± 1.691
2.117TyrVal: 2.117 ± 0.498
0.0TyrTrp: 0.0 ± 0.0
2.117TyrTyr: 2.117 ± 0.898
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2835 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski