Amino acid dipepetide frequency for Trichoplusia ni (Cabbage looper)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.421AlaAla: 8.421 ± 0.085
1.373AlaCys: 1.373 ± 0.024
3.644AlaAsp: 3.644 ± 0.021
4.77AlaGlu: 4.77 ± 0.032
2.16AlaPhe: 2.16 ± 0.017
4.661AlaGly: 4.661 ± 0.041
1.827AlaHis: 1.827 ± 0.016
3.16AlaIle: 3.16 ± 0.023
3.843AlaLys: 3.843 ± 0.028
6.951AlaLeu: 6.951 ± 0.048
1.516AlaMet: 1.516 ± 0.013
2.595AlaAsn: 2.595 ± 0.019
4.829AlaPro: 4.829 ± 0.037
2.87AlaGln: 2.87 ± 0.021
4.491AlaArg: 4.491 ± 0.032
5.345AlaSer: 5.345 ± 0.033
4.139AlaThr: 4.139 ± 0.03
4.763AlaVal: 4.763 ± 0.03
0.736AlaTrp: 0.736 ± 0.01
1.801AlaTyr: 1.801 ± 0.015
0.002AlaXaa: 0.002 ± 0.0
Cys
1.349CysAla: 1.349 ± 0.015
0.465CysCys: 0.465 ± 0.008
1.13CysAsp: 1.13 ± 0.016
1.13CysGlu: 1.13 ± 0.014
0.686CysPhe: 0.686 ± 0.014
1.348CysGly: 1.348 ± 0.025
0.463CysHis: 0.463 ± 0.007
0.912CysIle: 0.912 ± 0.017
1.031CysLys: 1.031 ± 0.015
1.639CysLeu: 1.639 ± 0.021
0.362CysMet: 0.362 ± 0.006
0.824CysAsn: 0.824 ± 0.014
1.057CysPro: 1.057 ± 0.029
0.684CysGln: 0.684 ± 0.013
1.12CysArg: 1.12 ± 0.023
1.458CysSer: 1.458 ± 0.023
1.02CysThr: 1.02 ± 0.019
1.334CysVal: 1.334 ± 0.022
0.211CysTrp: 0.211 ± 0.004
0.564CysTyr: 0.564 ± 0.011
0.001CysXaa: 0.001 ± 0.0
Asp
3.787AspAla: 3.787 ± 0.027
0.965AspCys: 0.965 ± 0.014
4.164AspAsp: 4.164 ± 0.04
4.519AspGlu: 4.519 ± 0.035
1.987AspPhe: 1.987 ± 0.017
3.168AspGly: 3.168 ± 0.024
1.197AspHis: 1.197 ± 0.01
3.192AspIle: 3.192 ± 0.019
3.639AspLys: 3.639 ± 0.03
4.787AspLeu: 4.787 ± 0.027
1.29AspMet: 1.29 ± 0.01
2.63AspAsn: 2.63 ± 0.022
2.695AspPro: 2.695 ± 0.034
1.686AspGln: 1.686 ± 0.012
2.755AspArg: 2.755 ± 0.026
4.453AspSer: 4.453 ± 0.03
3.211AspThr: 3.211 ± 0.026
3.767AspVal: 3.767 ± 0.025
0.625AspTrp: 0.625 ± 0.009
1.765AspTyr: 1.765 ± 0.015
0.001AspXaa: 0.001 ± 0.0
Glu
4.847GluAla: 4.847 ± 0.033
1.193GluCys: 1.193 ± 0.027
4.155GluAsp: 4.155 ± 0.029
6.116GluGlu: 6.116 ± 0.066
1.981GluPhe: 1.981 ± 0.014
3.39GluGly: 3.39 ± 0.033
1.545GluHis: 1.545 ± 0.013
3.675GluIle: 3.675 ± 0.043
5.053GluLys: 5.053 ± 0.064
6.03GluLeu: 6.03 ± 0.041
1.513GluMet: 1.513 ± 0.014
3.346GluAsn: 3.346 ± 0.021
3.364GluPro: 3.364 ± 0.036
3.087GluGln: 3.087 ± 0.056
4.241GluArg: 4.241 ± 0.034
4.723GluSer: 4.723 ± 0.037
3.93GluThr: 3.93 ± 0.045
4.114GluVal: 4.114 ± 0.029
0.739GluTrp: 0.739 ± 0.011
1.978GluTyr: 1.978 ± 0.016
0.001GluXaa: 0.001 ± 0.0
Phe
2.056PheAla: 2.056 ± 0.016
0.675PheCys: 0.675 ± 0.008
1.957PheAsp: 1.957 ± 0.015
2.004PheGlu: 2.004 ± 0.017
1.277PhePhe: 1.277 ± 0.015
2.115PheGly: 2.115 ± 0.019
0.818PheHis: 0.818 ± 0.009
1.859PheIle: 1.859 ± 0.016
1.966PheLys: 1.966 ± 0.015
2.995PheLeu: 2.995 ± 0.022
0.782PheMet: 0.782 ± 0.009
1.642PheAsn: 1.642 ± 0.013
1.491PhePro: 1.491 ± 0.014
1.215PheGln: 1.215 ± 0.011
1.816PheArg: 1.816 ± 0.016
2.497PheSer: 2.497 ± 0.014
1.991PheThr: 1.991 ± 0.015
2.214PheVal: 2.214 ± 0.016
0.379PheTrp: 0.379 ± 0.006
1.184PheTyr: 1.184 ± 0.013
0.001PheXaa: 0.001 ± 0.0
Gly
4.649GlyAla: 4.649 ± 0.044
1.002GlyCys: 1.002 ± 0.018
3.039GlyAsp: 3.039 ± 0.022
3.432GlyGlu: 3.432 ± 0.028
1.998GlyPhe: 1.998 ± 0.017
4.944GlyGly: 4.944 ± 0.053
1.406GlyHis: 1.406 ± 0.017
2.515GlyIle: 2.515 ± 0.019
3.192GlyLys: 3.192 ± 0.028
4.457GlyLeu: 4.457 ± 0.029
1.138GlyMet: 1.138 ± 0.012
2.356GlyAsn: 2.356 ± 0.018
2.924GlyPro: 2.924 ± 0.041
2.196GlyGln: 2.196 ± 0.065
3.155GlyArg: 3.155 ± 0.029
4.829GlySer: 4.829 ± 0.041
3.065GlyThr: 3.065 ± 0.021
3.635GlyVal: 3.635 ± 0.025
0.686GlyTrp: 0.686 ± 0.01
1.934GlyTyr: 1.934 ± 0.024
0.003GlyXaa: 0.003 ± 0.0
His
1.822HisAla: 1.822 ± 0.019
0.534HisCys: 0.534 ± 0.008
1.277HisAsp: 1.277 ± 0.012
1.443HisGlu: 1.443 ± 0.013
0.917HisPhe: 0.917 ± 0.01
1.334HisGly: 1.334 ± 0.012
1.086HisHis: 1.086 ± 0.02
1.282HisIle: 1.282 ± 0.011
1.417HisLys: 1.417 ± 0.013
2.217HisLeu: 2.217 ± 0.016
0.619HisMet: 0.619 ± 0.007
1.144HisAsn: 1.144 ± 0.012
1.403HisPro: 1.403 ± 0.014
1.045HisGln: 1.045 ± 0.011
1.429HisArg: 1.429 ± 0.012
1.919HisSer: 1.919 ± 0.017
1.496HisThr: 1.496 ± 0.016
1.52HisVal: 1.52 ± 0.011
0.286HisTrp: 0.286 ± 0.005
0.904HisTyr: 0.904 ± 0.008
0.001HisXaa: 0.001 ± 0.0
Ile
3.231IleAla: 3.231 ± 0.018
1.02IleCys: 1.02 ± 0.016
2.958IleAsp: 2.958 ± 0.021
3.432IleGlu: 3.432 ± 0.033
1.801IlePhe: 1.801 ± 0.018
2.446IleGly: 2.446 ± 0.019
1.178IleHis: 1.178 ± 0.011
2.906IleIle: 2.906 ± 0.023
3.5IleLys: 3.5 ± 0.031
4.276IleLeu: 4.276 ± 0.024
1.084IleMet: 1.084 ± 0.011
2.492IleAsn: 2.492 ± 0.018
2.577IlePro: 2.577 ± 0.017
2.069IleGln: 2.069 ± 0.017
2.483IleArg: 2.483 ± 0.015
3.749IleSer: 3.749 ± 0.022
3.245IleThr: 3.245 ± 0.032
3.315IleVal: 3.315 ± 0.023
0.438IleTrp: 0.438 ± 0.006
1.495IleTyr: 1.495 ± 0.013
0.001IleXaa: 0.001 ± 0.0
Lys
3.735LysAla: 3.735 ± 0.032
1.165LysCys: 1.165 ± 0.02
3.784LysAsp: 3.784 ± 0.037
4.925LysGlu: 4.925 ± 0.052
1.938LysPhe: 1.938 ± 0.015
2.672LysGly: 2.672 ± 0.022
1.582LysHis: 1.582 ± 0.016
3.399LysIle: 3.399 ± 0.028
5.558LysLys: 5.558 ± 0.075
5.464LysLeu: 5.464 ± 0.034
1.479LysMet: 1.479 ± 0.013
3.033LysAsn: 3.033 ± 0.023
3.75LysPro: 3.75 ± 0.059
2.673LysGln: 2.673 ± 0.023
3.688LysArg: 3.688 ± 0.026
4.462LysSer: 4.462 ± 0.03
3.747LysThr: 3.747 ± 0.035
3.755LysVal: 3.755 ± 0.032
0.633LysTrp: 0.633 ± 0.012
2.083LysTyr: 2.083 ± 0.018
0.003LysXaa: 0.003 ± 0.001
Leu
6.71LeuAla: 6.71 ± 0.041
1.733LeuCys: 1.733 ± 0.014
4.811LeuAsp: 4.811 ± 0.03
6.039LeuGlu: 6.039 ± 0.043
2.871LeuPhe: 2.871 ± 0.025
4.366LeuGly: 4.366 ± 0.028
2.312LeuHis: 2.312 ± 0.016
3.954LeuIle: 3.954 ± 0.023
5.707LeuLys: 5.707 ± 0.038
8.462LeuLeu: 8.462 ± 0.051
1.89LeuMet: 1.89 ± 0.015
3.951LeuAsn: 3.951 ± 0.023
4.854LeuPro: 4.854 ± 0.033
4.304LeuGln: 4.304 ± 0.026
5.486LeuArg: 5.486 ± 0.033
6.642LeuSer: 6.642 ± 0.031
4.945LeuThr: 4.945 ± 0.026
5.244LeuVal: 5.244 ± 0.03
0.858LeuTrp: 0.858 ± 0.011
2.469LeuTyr: 2.469 ± 0.019
0.002LeuXaa: 0.002 ± 0.0
Met
1.572MetAla: 1.572 ± 0.012
0.431MetCys: 0.431 ± 0.007
1.255MetAsp: 1.255 ± 0.011
1.561MetGlu: 1.561 ± 0.012
0.853MetPhe: 0.853 ± 0.011
1.135MetGly: 1.135 ± 0.018
0.514MetHis: 0.514 ± 0.007
0.946MetIle: 0.946 ± 0.009
1.389MetLys: 1.389 ± 0.012
1.924MetLeu: 1.924 ± 0.017
0.612MetMet: 0.612 ± 0.009
0.988MetAsn: 0.988 ± 0.011
1.123MetPro: 1.123 ± 0.012
0.955MetGln: 0.955 ± 0.012
1.192MetArg: 1.192 ± 0.012
1.814MetSer: 1.814 ± 0.013
1.208MetThr: 1.208 ± 0.01
1.229MetVal: 1.229 ± 0.011
0.25MetTrp: 0.25 ± 0.005
0.701MetTyr: 0.701 ± 0.008
0.001MetXaa: 0.001 ± 0.0
Asn
2.797AsnAla: 2.797 ± 0.022
0.81AsnCys: 0.81 ± 0.013
2.462AsnAsp: 2.462 ± 0.018
2.992AsnGlu: 2.992 ± 0.019
1.619AsnPhe: 1.619 ± 0.013
2.647AsnGly: 2.647 ± 0.023
0.984AsnHis: 0.984 ± 0.012
2.883AsnIle: 2.883 ± 0.018
3.093AsnLys: 3.093 ± 0.023
3.923AsnLeu: 3.923 ± 0.024
1.153AsnMet: 1.153 ± 0.011
2.755AsnAsn: 2.755 ± 0.025
2.112AsnPro: 2.112 ± 0.025
1.728AsnGln: 1.728 ± 0.016
2.125AsnArg: 2.125 ± 0.017
3.506AsnSer: 3.506 ± 0.028
2.685AsnThr: 2.685 ± 0.019
3.083AsnVal: 3.083 ± 0.02
0.432AsnTrp: 0.432 ± 0.006
1.51AsnTyr: 1.51 ± 0.016
0.001AsnXaa: 0.001 ± 0.0
Pro
4.941ProAla: 4.941 ± 0.039
0.802ProCys: 0.802 ± 0.03
3.009ProAsp: 3.009 ± 0.02
3.98ProGlu: 3.98 ± 0.043
1.53ProPhe: 1.53 ± 0.014
3.455ProGly: 3.455 ± 0.115
1.557ProHis: 1.557 ± 0.017
2.451ProIle: 2.451 ± 0.022
3.675ProLys: 3.675 ± 0.079
4.403ProLeu: 4.403 ± 0.027
1.053ProMet: 1.053 ± 0.012
2.265ProAsn: 2.265 ± 0.021
5.603ProPro: 5.603 ± 0.062
2.36ProGln: 2.36 ± 0.02
3.2ProArg: 3.2 ± 0.036
4.607ProSer: 4.607 ± 0.044
3.654ProThr: 3.654 ± 0.045
3.669ProVal: 3.669 ± 0.032
0.473ProTrp: 0.473 ± 0.007
1.558ProTyr: 1.558 ± 0.018
0.003ProXaa: 0.003 ± 0.001
Gln
2.831GlnAla: 2.831 ± 0.02
0.75GlnCys: 0.75 ± 0.015
1.926GlnAsp: 1.926 ± 0.013
2.797GlnGlu: 2.797 ± 0.031
1.29GlnPhe: 1.29 ± 0.01
2.004GlnGly: 2.004 ± 0.03
1.217GlnHis: 1.217 ± 0.014
2.027GlnIle: 2.027 ± 0.013
2.458GlnLys: 2.458 ± 0.024
3.891GlnLeu: 3.891 ± 0.027
0.986GlnMet: 0.986 ± 0.012
1.959GlnAsn: 1.959 ± 0.017
2.947GlnPro: 2.947 ± 0.082
2.88GlnGln: 2.88 ± 0.059
2.5GlnArg: 2.5 ± 0.023
2.756GlnSer: 2.756 ± 0.019
2.187GlnThr: 2.187 ± 0.018
2.403GlnVal: 2.403 ± 0.02
0.458GlnTrp: 0.458 ± 0.007
1.293GlnTyr: 1.293 ± 0.013
0.001GlnXaa: 0.001 ± 0.0
Arg
4.563ArgAla: 4.563 ± 0.037
1.151ArgCys: 1.151 ± 0.03
3.203ArgAsp: 3.203 ± 0.025
3.674ArgGlu: 3.674 ± 0.029
1.764ArgPhe: 1.764 ± 0.013
3.128ArgGly: 3.128 ± 0.031
1.608ArgHis: 1.608 ± 0.015
2.531ArgIle: 2.531 ± 0.015
3.57ArgLys: 3.57 ± 0.023
5.193ArgLeu: 5.193 ± 0.034
1.142ArgMet: 1.142 ± 0.01
2.473ArgAsn: 2.473 ± 0.018
3.156ArgPro: 3.156 ± 0.029
2.347ArgGln: 2.347 ± 0.019
4.811ArgArg: 4.811 ± 0.037
4.309ArgSer: 4.309 ± 0.028
2.909ArgThr: 2.909 ± 0.02
3.414ArgVal: 3.414 ± 0.022
0.689ArgTrp: 0.689 ± 0.008
1.692ArgTyr: 1.692 ± 0.015
0.002ArgXaa: 0.002 ± 0.0
Ser
5.294SerAla: 5.294 ± 0.033
1.361SerCys: 1.361 ± 0.023
4.499SerAsp: 4.499 ± 0.027
5.151SerGlu: 5.151 ± 0.029
2.428SerPhe: 2.428 ± 0.017
4.819SerGly: 4.819 ± 0.036
1.773SerHis: 1.773 ± 0.015
3.535SerIle: 3.535 ± 0.021
4.401SerLys: 4.401 ± 0.028
6.558SerLeu: 6.558 ± 0.035
1.561SerMet: 1.561 ± 0.012
3.432SerAsn: 3.432 ± 0.028
4.891SerPro: 4.891 ± 0.046
2.985SerGln: 2.985 ± 0.022
4.214SerArg: 4.214 ± 0.028
8.056SerSer: 8.056 ± 0.08
5.255SerThr: 5.255 ± 0.074
4.733SerVal: 4.733 ± 0.023
0.786SerTrp: 0.786 ± 0.008
2.088SerTyr: 2.088 ± 0.017
0.002SerXaa: 0.002 ± 0.0
Thr
4.176ThrAla: 4.176 ± 0.024
1.106ThrCys: 1.106 ± 0.018
3.19ThrAsp: 3.19 ± 0.023
4.231ThrGlu: 4.231 ± 0.07
2.01ThrPhe: 2.01 ± 0.014
3.289ThrGly: 3.289 ± 0.027
1.44ThrHis: 1.44 ± 0.015
3.093ThrIle: 3.093 ± 0.024
3.572ThrLys: 3.572 ± 0.033
5.112ThrLeu: 5.112 ± 0.025
1.154ThrMet: 1.154 ± 0.01
2.553ThrAsn: 2.553 ± 0.018
4.056ThrPro: 4.056 ± 0.034
2.335ThrGln: 2.335 ± 0.025
2.728ThrArg: 2.728 ± 0.018
4.915ThrSer: 4.915 ± 0.038
5.473ThrThr: 5.473 ± 0.169
4.118ThrVal: 4.118 ± 0.049
0.598ThrTrp: 0.598 ± 0.009
1.663ThrTyr: 1.663 ± 0.015
0.001ThrXaa: 0.001 ± 0.0
Val
4.651ValAla: 4.651 ± 0.03
1.35ValCys: 1.35 ± 0.02
3.482ValAsp: 3.482 ± 0.026
4.259ValGlu: 4.259 ± 0.045
2.208ValPhe: 2.208 ± 0.019
3.206ValGly: 3.206 ± 0.022
1.519ValHis: 1.519 ± 0.012
3.326ValIle: 3.326 ± 0.026
4.008ValLys: 4.008 ± 0.038
5.598ValLeu: 5.598 ± 0.031
1.364ValMet: 1.364 ± 0.011
2.831ValAsn: 2.831 ± 0.02
3.523ValPro: 3.523 ± 0.023
2.519ValGln: 2.519 ± 0.018
3.402ValArg: 3.402 ± 0.022
4.766ValSer: 4.766 ± 0.022
4.306ValThr: 4.306 ± 0.049
4.366ValVal: 4.366 ± 0.028
0.687ValTrp: 0.687 ± 0.01
1.863ValTyr: 1.863 ± 0.014
0.001ValXaa: 0.001 ± 0.0
Trp
0.662TrpAla: 0.662 ± 0.008
0.23TrpCys: 0.23 ± 0.005
0.591TrpAsp: 0.591 ± 0.007
0.656TrpGlu: 0.656 ± 0.009
0.412TrpPhe: 0.412 ± 0.007
0.557TrpGly: 0.557 ± 0.01
0.246TrpHis: 0.246 ± 0.005
0.51TrpIle: 0.51 ± 0.008
0.619TrpLys: 0.619 ± 0.01
1.089TrpLeu: 1.089 ± 0.013
0.266TrpMet: 0.266 ± 0.005
0.482TrpAsn: 0.482 ± 0.007
0.44TrpPro: 0.44 ± 0.007
0.424TrpGln: 0.424 ± 0.006
0.778TrpArg: 0.778 ± 0.011
0.784TrpSer: 0.784 ± 0.009
0.575TrpThr: 0.575 ± 0.009
0.637TrpVal: 0.637 ± 0.007
0.204TrpTrp: 0.204 ± 0.004
0.355TrpTyr: 0.355 ± 0.006
0.001TrpXaa: 0.001 ± 0.0
Tyr
1.8TyrAla: 1.8 ± 0.015
0.67TyrCys: 0.67 ± 0.009
1.747TyrAsp: 1.747 ± 0.015
1.91TyrGlu: 1.91 ± 0.015
1.203TyrPhe: 1.203 ± 0.012
1.865TyrGly: 1.865 ± 0.021
0.822TyrHis: 0.822 ± 0.009
1.535TyrIle: 1.535 ± 0.014
1.834TyrLys: 1.834 ± 0.016
2.64TyrLeu: 2.64 ± 0.021
0.689TyrMet: 0.689 ± 0.008
1.55TyrAsn: 1.55 ± 0.014
1.45TyrPro: 1.45 ± 0.025
1.198TyrGln: 1.198 ± 0.011
1.712TyrArg: 1.712 ± 0.013
2.233TyrSer: 2.233 ± 0.017
1.769TyrThr: 1.769 ± 0.015
1.922TyrVal: 1.922 ± 0.015
0.35TyrTrp: 0.35 ± 0.006
1.186TyrTyr: 1.186 ± 0.013
0.001TyrXaa: 0.001 ± 0.0
Xaa
0.002XaaAla: 0.002 ± 0.0
0.001XaaCys: 0.001 ± 0.0
0.002XaaAsp: 0.002 ± 0.0
0.002XaaGlu: 0.002 ± 0.0
0.001XaaPhe: 0.001 ± 0.0
0.003XaaGly: 0.003 ± 0.001
0.0XaaHis: 0.0 ± 0.0
0.002XaaIle: 0.002 ± 0.001
0.002XaaLys: 0.002 ± 0.0
0.003XaaLeu: 0.003 ± 0.001
0.0XaaMet: 0.0 ± 0.0
0.001XaaAsn: 0.001 ± 0.0
0.002XaaPro: 0.002 ± 0.0
0.001XaaGln: 0.001 ± 0.0
0.002XaaArg: 0.002 ± 0.0
0.002XaaSer: 0.002 ± 0.0
0.001XaaThr: 0.001 ± 0.0
0.001XaaVal: 0.001 ± 0.0
0.001XaaTrp: 0.001 ± 0.0
0.001XaaTyr: 0.001 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 20889 proteins (13497636 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski