Amino acid dipepetide frequency for Pteropus associated gemycircularvirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.039AlaAla: 6.039 ± 1.524
0.0AlaCys: 0.0 ± 0.0
8.454AlaAsp: 8.454 ± 4.087
2.415AlaGlu: 2.415 ± 1.21
1.208AlaPhe: 1.208 ± 0.976
6.039AlaGly: 6.039 ± 1.524
1.208AlaHis: 1.208 ± 0.976
2.415AlaIle: 2.415 ± 1.21
4.831AlaLys: 4.831 ± 0.89
3.623AlaLeu: 3.623 ± 2.928
0.0AlaMet: 0.0 ± 0.0
6.039AlaAsn: 6.039 ± 3.357
2.415AlaPro: 2.415 ± 1.952
3.623AlaGln: 3.623 ± 0.418
3.623AlaArg: 3.623 ± 1.495
2.415AlaSer: 2.415 ± 1.21
6.039AlaThr: 6.039 ± 1.82
2.415AlaVal: 2.415 ± 0.759
1.208AlaTrp: 1.208 ± 0.976
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.208CysAla: 1.208 ± 0.976
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.208CysPhe: 1.208 ± 0.976
3.623CysGly: 3.623 ± 1.786
0.0CysHis: 0.0 ± 0.0
4.831CysIle: 4.831 ± 2.562
0.0CysLys: 0.0 ± 0.0
1.208CysLeu: 1.208 ± 0.908
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.208CysGln: 1.208 ± 0.908
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.831AspAla: 4.831 ± 0.838
0.0AspCys: 0.0 ± 0.0
7.246AspAsp: 7.246 ± 3.572
0.0AspGlu: 0.0 ± 0.0
3.623AspPhe: 3.623 ± 0.418
9.662AspGly: 9.662 ± 4.839
0.0AspHis: 0.0 ± 0.0
3.623AspIle: 3.623 ± 0.418
1.208AspLys: 1.208 ± 0.976
9.662AspLeu: 9.662 ± 1.88
1.208AspMet: 1.208 ± 0.908
1.208AspAsn: 1.208 ± 1.177
12.077AspPro: 12.077 ± 2.729
0.0AspGln: 0.0 ± 0.0
3.623AspArg: 3.623 ± 0.418
1.208AspSer: 1.208 ± 0.908
6.039AspThr: 6.039 ± 4.88
6.039AspVal: 6.039 ± 2.913
7.246AspTrp: 7.246 ± 0.836
3.623AspTyr: 3.623 ± 1.786
0.0AspXaa: 0.0 ± 0.0
Glu
2.415GluAla: 2.415 ± 1.952
2.415GluCys: 2.415 ± 1.21
1.208GluAsp: 1.208 ± 0.976
2.415GluGlu: 2.415 ± 1.21
1.208GluPhe: 1.208 ± 0.976
3.623GluGly: 3.623 ± 0.418
0.0GluHis: 0.0 ± 0.0
1.208GluIle: 1.208 ± 0.976
1.208GluLys: 1.208 ± 0.976
6.039GluLeu: 6.039 ± 2.913
0.0GluMet: 0.0 ± 0.771
2.415GluAsn: 2.415 ± 1.138
2.415GluPro: 2.415 ± 1.21
2.415GluGln: 2.415 ± 1.21
2.415GluArg: 2.415 ± 1.21
3.623GluSer: 3.623 ± 1.786
1.208GluThr: 1.208 ± 0.976
1.208GluVal: 1.208 ± 0.908
2.415GluTrp: 2.415 ± 1.21
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.623PheAla: 3.623 ± 0.418
1.208PheCys: 1.208 ± 0.908
6.039PheAsp: 6.039 ± 2.913
2.415PheGlu: 2.415 ± 1.21
4.831PhePhe: 4.831 ± 0.838
6.039PheGly: 6.039 ± 0.344
2.415PheHis: 2.415 ± 1.815
1.208PheIle: 1.208 ± 0.976
0.0PheLys: 0.0 ± 0.0
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
1.208PheAsn: 1.208 ± 0.976
3.623PhePro: 3.623 ± 0.418
1.208PheGln: 1.208 ± 0.908
8.454PheArg: 8.454 ± 0.99
3.623PheSer: 3.623 ± 1.495
0.0PheThr: 0.0 ± 0.0
8.454PheVal: 8.454 ± 4.087
0.0PheTrp: 0.0 ± 0.0
1.208PheTyr: 1.208 ± 0.976
0.0PheXaa: 0.0 ± 0.0
Gly
3.623GlyAla: 3.623 ± 2.928
1.208GlyCys: 1.208 ± 0.908
7.246GlyAsp: 7.246 ± 0.836
4.831GlyGlu: 4.831 ± 0.838
2.415GlyPhe: 2.415 ± 1.952
13.285GlyGly: 13.285 ± 0.499
1.208GlyHis: 1.208 ± 0.908
7.246GlyIle: 7.246 ± 1.937
4.831GlyLys: 4.831 ± 2.184
10.87GlyLeu: 10.87 ± 2.16
0.0GlyMet: 0.0 ± 0.0
4.831GlyAsn: 4.831 ± 0.89
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
12.077GlyArg: 12.077 ± 3.049
4.831GlySer: 4.831 ± 0.838
4.831GlyThr: 4.831 ± 2.419
1.208GlyVal: 1.208 ± 0.976
1.208GlyTrp: 1.208 ± 0.908
2.415GlyTyr: 2.415 ± 1.21
0.0GlyXaa: 0.0 ± 0.0
His
1.208HisAla: 1.208 ± 0.908
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.208HisGlu: 1.208 ± 0.976
2.415HisPhe: 2.415 ± 1.21
1.208HisGly: 1.208 ± 0.908
1.208HisHis: 1.208 ± 0.908
1.208HisIle: 1.208 ± 0.976
0.0HisLys: 0.0 ± 0.0
2.415HisLeu: 2.415 ± 1.21
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.623HisPro: 3.623 ± 0.418
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
4.831HisSer: 4.831 ± 2.419
0.0HisThr: 0.0 ± 0.0
3.623HisVal: 3.623 ± 1.786
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.831IleAla: 4.831 ± 0.89
0.0IleCys: 0.0 ± 0.0
1.208IleAsp: 1.208 ± 0.976
0.0IleGlu: 0.0 ± 0.0
6.039IlePhe: 6.039 ± 1.696
2.415IleGly: 2.415 ± 1.952
4.831IleHis: 4.831 ± 2.419
2.415IleIle: 2.415 ± 1.952
2.415IleLys: 2.415 ± 1.21
1.208IleLeu: 1.208 ± 0.976
1.208IleMet: 1.208 ± 0.976
2.415IleAsn: 2.415 ± 0.759
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
2.415IleArg: 2.415 ± 1.952
1.208IleSer: 1.208 ± 0.908
8.454IleThr: 8.454 ± 3.751
6.039IleVal: 6.039 ± 1.524
3.623IleTrp: 3.623 ± 1.495
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
2.415LysAsp: 2.415 ± 1.21
2.415LysGlu: 2.415 ± 0.759
4.831LysPhe: 4.831 ± 2.419
1.208LysGly: 1.208 ± 0.976
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
2.415LysLys: 2.415 ± 1.952
2.415LysLeu: 2.415 ± 1.21
1.208LysMet: 1.208 ± 0.781
3.623LysAsn: 3.623 ± 1.36
0.0LysPro: 0.0 ± 0.0
2.415LysGln: 2.415 ± 1.815
3.623LysArg: 3.623 ± 2.928
6.039LysSer: 6.039 ± 0.344
4.831LysThr: 4.831 ± 0.838
1.208LysVal: 1.208 ± 0.976
2.415LysTrp: 2.415 ± 1.21
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
1.208LeuCys: 1.208 ± 0.908
9.662LeuAsp: 9.662 ± 1.88
2.415LeuGlu: 2.415 ± 1.21
3.623LeuPhe: 3.623 ± 1.786
3.623LeuGly: 3.623 ± 1.36
4.831LeuHis: 4.831 ± 2.419
0.0LeuIle: 0.0 ± 0.0
1.208LeuLys: 1.208 ± 0.976
8.454LeuLeu: 8.454 ± 0.964
0.0LeuMet: 0.0 ± 0.0
3.623LeuAsn: 3.623 ± 1.36
4.831LeuPro: 4.831 ± 3.904
8.454LeuGln: 8.454 ± 2.72
1.208LeuArg: 1.208 ± 0.976
4.831LeuSer: 4.831 ± 0.89
4.831LeuThr: 4.831 ± 0.89
4.831LeuVal: 4.831 ± 1.594
1.208LeuTrp: 1.208 ± 0.908
4.831LeuTyr: 4.831 ± 2.408
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.208MetLys: 1.208 ± 0.908
1.208MetLeu: 1.208 ± 0.976
1.208MetMet: 1.208 ± 0.976
0.0MetAsn: 0.0 ± 0.0
3.623MetPro: 3.623 ± 0.418
1.208MetGln: 1.208 ± 0.908
1.208MetArg: 1.208 ± 0.976
0.0MetSer: 0.0 ± 0.0
1.208MetThr: 1.208 ± 0.976
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.208MetTyr: 1.208 ± 0.908
0.0MetXaa: 0.0 ± 0.0
Asn
1.208AsnAla: 1.208 ± 0.976
1.208AsnCys: 1.208 ± 0.908
4.831AsnAsp: 4.831 ± 2.408
1.208AsnGlu: 1.208 ± 0.976
1.208AsnPhe: 1.208 ± 0.908
4.831AsnGly: 4.831 ± 2.419
1.208AsnHis: 1.208 ± 1.177
2.415AsnIle: 2.415 ± 1.21
2.415AsnLys: 2.415 ± 0.759
4.831AsnLeu: 4.831 ± 0.89
0.0AsnMet: 0.0 ± 0.0
3.623AsnAsn: 3.623 ± 1.786
1.208AsnPro: 1.208 ± 0.976
0.0AsnGln: 0.0 ± 0.0
2.415AsnArg: 2.415 ± 1.952
4.831AsnSer: 4.831 ± 0.89
2.415AsnThr: 2.415 ± 0.759
4.831AsnVal: 4.831 ± 0.838
1.208AsnTrp: 1.208 ± 0.908
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.208ProAla: 1.208 ± 0.976
0.0ProCys: 0.0 ± 0.0
2.415ProAsp: 2.415 ± 1.21
6.039ProGlu: 6.039 ± 1.524
3.623ProPhe: 3.623 ± 0.418
2.415ProGly: 2.415 ± 1.952
0.0ProHis: 0.0 ± 0.0
2.415ProIle: 2.415 ± 0.759
2.415ProLys: 2.415 ± 1.21
4.831ProLeu: 4.831 ± 3.904
0.0ProMet: 0.0 ± 0.0
4.831ProAsn: 4.831 ± 2.419
1.208ProPro: 1.208 ± 0.976
1.208ProGln: 1.208 ± 0.976
4.831ProArg: 4.831 ± 0.838
2.415ProSer: 2.415 ± 1.21
4.831ProThr: 4.831 ± 0.89
4.831ProVal: 4.831 ± 2.408
0.0ProTrp: 0.0 ± 0.0
2.415ProTyr: 2.415 ± 1.21
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
2.415GlnCys: 2.415 ± 1.21
3.623GlnAsp: 3.623 ± 0.418
1.208GlnGlu: 1.208 ± 0.976
2.415GlnPhe: 2.415 ± 1.21
3.623GlnGly: 3.623 ± 1.786
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
1.208GlnLeu: 1.208 ± 0.908
2.415GlnMet: 2.415 ± 0.759
0.0GlnAsn: 0.0 ± 0.0
1.208GlnPro: 1.208 ± 0.908
1.208GlnGln: 1.208 ± 0.976
3.623GlnArg: 3.623 ± 0.418
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
2.415GlnVal: 2.415 ± 1.815
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.831ArgAla: 4.831 ± 2.419
0.0ArgCys: 0.0 ± 0.0
4.831ArgAsp: 4.831 ± 0.838
7.246ArgGlu: 7.246 ± 3.629
4.831ArgPhe: 4.831 ± 0.89
2.415ArgGly: 2.415 ± 1.952
2.415ArgHis: 2.415 ± 1.21
8.454ArgIle: 8.454 ± 6.832
3.623ArgLys: 3.623 ± 0.418
3.623ArgLeu: 3.623 ± 1.786
0.0ArgMet: 0.0 ± 0.0
1.208ArgAsn: 1.208 ± 0.976
4.831ArgPro: 4.831 ± 0.89
1.208ArgGln: 1.208 ± 0.976
12.077ArgArg: 12.077 ± 9.76
9.662ArgSer: 9.662 ± 3.12
3.623ArgThr: 3.623 ± 2.928
2.415ArgVal: 2.415 ± 1.952
1.208ArgTrp: 1.208 ± 0.976
6.039ArgTyr: 6.039 ± 1.82
0.0ArgXaa: 0.0 ± 0.0
Ser
6.039SerAla: 6.039 ± 1.82
1.208SerCys: 1.208 ± 0.908
6.039SerAsp: 6.039 ± 1.524
0.0SerGlu: 0.0 ± 0.0
1.208SerPhe: 1.208 ± 0.908
4.831SerGly: 4.831 ± 0.838
0.0SerHis: 0.0 ± 0.0
1.208SerIle: 1.208 ± 0.976
0.0SerLys: 0.0 ± 0.0
6.039SerLeu: 6.039 ± 1.696
2.415SerMet: 2.415 ± 1.086
3.623SerAsn: 3.623 ± 1.786
2.415SerPro: 2.415 ± 1.952
0.0SerGln: 0.0 ± 0.0
9.662SerArg: 9.662 ± 3.12
8.454SerSer: 8.454 ± 5.284
4.831SerThr: 4.831 ± 3.904
2.415SerVal: 2.415 ± 1.21
2.415SerTrp: 2.415 ± 1.21
1.208SerTyr: 1.208 ± 0.976
0.0SerXaa: 0.0 ± 0.0
Thr
4.831ThrAla: 4.831 ± 3.904
1.208ThrCys: 1.208 ± 0.976
3.623ThrAsp: 3.623 ± 0.418
4.831ThrGlu: 4.831 ± 2.408
4.831ThrPhe: 4.831 ± 0.89
3.623ThrGly: 3.623 ± 2.928
0.0ThrHis: 0.0 ± 0.0
6.039ThrIle: 6.039 ± 1.82
2.415ThrLys: 2.415 ± 1.952
2.415ThrLeu: 2.415 ± 0.759
1.208ThrMet: 1.208 ± 0.976
1.208ThrAsn: 1.208 ± 0.976
7.246ThrPro: 7.246 ± 3.629
1.208ThrGln: 1.208 ± 0.908
4.831ThrArg: 4.831 ± 0.89
3.623ThrSer: 3.623 ± 2.928
2.415ThrThr: 2.415 ± 1.952
2.415ThrVal: 2.415 ± 1.952
1.208ThrTrp: 1.208 ± 0.908
3.623ThrTyr: 3.623 ± 0.418
0.0ThrXaa: 0.0 ± 0.0
Val
6.039ValAla: 6.039 ± 1.524
0.0ValCys: 0.0 ± 0.0
9.662ValAsp: 9.662 ± 1.675
1.208ValGlu: 1.208 ± 0.908
3.623ValPhe: 3.623 ± 1.786
8.454ValGly: 8.454 ± 2.72
1.208ValHis: 1.208 ± 0.908
2.415ValIle: 2.415 ± 1.952
3.623ValLys: 3.623 ± 1.786
2.415ValLeu: 2.415 ± 1.138
0.0ValMet: 0.0 ± 0.0
4.831ValAsn: 4.831 ± 0.838
1.208ValPro: 1.208 ± 0.976
0.0ValGln: 0.0 ± 0.0
3.623ValArg: 3.623 ± 1.764
1.208ValSer: 1.208 ± 0.976
7.246ValThr: 7.246 ± 1.045
6.039ValVal: 6.039 ± 1.524
1.208ValTrp: 1.208 ± 0.976
1.208ValTyr: 1.208 ± 0.908
0.0ValXaa: 0.0 ± 0.0
Trp
3.623TrpAla: 3.623 ± 1.786
1.208TrpCys: 1.208 ± 0.976
0.0TrpAsp: 0.0 ± 0.0
1.208TrpGlu: 1.208 ± 1.177
1.208TrpPhe: 1.208 ± 0.908
4.831TrpGly: 4.831 ± 2.562
2.415TrpHis: 2.415 ± 1.952
1.208TrpIle: 1.208 ± 0.908
3.623TrpLys: 3.623 ± 1.786
1.208TrpLeu: 1.208 ± 0.976
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.415TrpArg: 2.415 ± 1.952
1.208TrpSer: 1.208 ± 0.976
0.0TrpThr: 0.0 ± 0.0
3.623TrpVal: 3.623 ± 0.418
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
8.454TyrAla: 8.454 ± 0.964
0.0TyrCys: 0.0 ± 0.0
3.623TyrAsp: 3.623 ± 0.418
0.0TyrGlu: 0.0 ± 0.0
1.208TyrPhe: 1.208 ± 0.908
2.415TyrGly: 2.415 ± 0.759
0.0TyrHis: 0.0 ± 0.0
2.415TyrIle: 2.415 ± 1.21
3.623TyrLys: 3.623 ± 0.418
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
1.208TyrAsn: 1.208 ± 0.976
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
2.415TyrArg: 2.415 ± 0.759
0.0TyrSer: 0.0 ± 0.0
0.0TyrThr: 0.0 ± 0.0
1.208TyrVal: 1.208 ± 0.976
1.208TyrTrp: 1.208 ± 0.976
1.208TyrTyr: 1.208 ± 0.976
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (829 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski