Amino acid dipepetide frequency for Hubei diptera virus 17

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.958AlaAla: 5.958 ± 0.244
1.986AlaCys: 1.986 ± 1.282
3.972AlaAsp: 3.972 ± 1.526
4.965AlaGlu: 4.965 ± 0.885
3.972AlaPhe: 3.972 ± 0.163
4.965AlaGly: 4.965 ± 2.249
0.993AlaHis: 0.993 ± 0.722
0.993AlaIle: 0.993 ± 0.641
2.979AlaLys: 2.979 ± 0.56
4.965AlaLeu: 4.965 ± 0.479
1.986AlaMet: 1.986 ± 0.571
1.986AlaAsn: 1.986 ± 0.081
3.972AlaPro: 3.972 ± 2.89
4.965AlaGln: 4.965 ± 2.249
6.951AlaArg: 6.951 ± 0.397
9.93AlaSer: 9.93 ± 4.497
2.979AlaThr: 2.979 ± 0.804
5.958AlaVal: 5.958 ± 1.607
0.993AlaTrp: 0.993 ± 0.641
3.972AlaTyr: 3.972 ± 1.201
0.0AlaXaa: 0.0 ± 0.0
Cys
2.979CysAla: 2.979 ± 0.804
0.0CysCys: 0.0 ± 0.0
0.993CysAsp: 0.993 ± 0.641
0.993CysGlu: 0.993 ± 0.722
0.993CysPhe: 0.993 ± 0.641
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.993CysIle: 0.993 ± 0.641
1.986CysLys: 1.986 ± 1.282
1.986CysLeu: 1.986 ± 0.081
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.993CysGln: 0.993 ± 0.722
0.0CysArg: 0.0 ± 0.0
0.993CysSer: 0.993 ± 0.641
0.993CysThr: 0.993 ± 0.641
0.0CysVal: 0.0 ± 0.0
0.993CysTrp: 0.993 ± 0.641
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.958AspAla: 5.958 ± 0.244
0.0AspCys: 0.0 ± 0.0
2.979AspAsp: 2.979 ± 0.56
1.986AspGlu: 1.986 ± 0.081
4.965AspPhe: 4.965 ± 0.479
2.979AspGly: 2.979 ± 0.56
0.0AspHis: 0.0 ± 0.0
2.979AspIle: 2.979 ± 2.167
1.986AspLys: 1.986 ± 1.282
7.944AspLeu: 7.944 ± 0.325
0.0AspMet: 0.0 ± 0.0
1.986AspAsn: 1.986 ± 0.081
1.986AspPro: 1.986 ± 0.081
0.993AspGln: 0.993 ± 0.641
0.993AspArg: 0.993 ± 0.641
1.986AspSer: 1.986 ± 0.081
1.986AspThr: 1.986 ± 0.081
3.972AspVal: 3.972 ± 2.565
3.972AspTrp: 3.972 ± 2.565
2.979AspTyr: 2.979 ± 0.804
0.0AspXaa: 0.0 ± 0.0
Glu
2.979GluAla: 2.979 ± 0.56
0.993GluCys: 0.993 ± 0.641
0.993GluAsp: 0.993 ± 0.641
1.986GluGlu: 1.986 ± 1.282
1.986GluPhe: 1.986 ± 0.081
2.979GluGly: 2.979 ± 1.924
1.986GluHis: 1.986 ± 1.282
3.972GluIle: 3.972 ± 0.163
1.986GluLys: 1.986 ± 0.081
5.958GluLeu: 5.958 ± 0.244
1.986GluMet: 1.986 ± 0.081
1.986GluAsn: 1.986 ± 1.445
0.0GluPro: 0.0 ± 0.0
1.986GluGln: 1.986 ± 1.445
0.993GluArg: 0.993 ± 0.641
2.979GluSer: 2.979 ± 2.167
2.979GluThr: 2.979 ± 1.924
2.979GluVal: 2.979 ± 0.56
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.965PheAla: 4.965 ± 0.885
0.0PheCys: 0.0 ± 0.0
2.979PheAsp: 2.979 ± 0.56
1.986PheGlu: 1.986 ± 0.081
0.993PhePhe: 0.993 ± 0.641
4.965PheGly: 4.965 ± 0.885
0.0PheHis: 0.0 ± 0.0
0.993PheIle: 0.993 ± 0.641
1.986PheLys: 1.986 ± 1.282
2.979PheLeu: 2.979 ± 1.924
0.993PheMet: 0.993 ± 0.722
4.965PheAsn: 4.965 ± 3.206
6.951PhePro: 6.951 ± 0.397
0.993PheGln: 0.993 ± 0.722
2.979PheArg: 2.979 ± 0.804
0.993PheSer: 0.993 ± 0.722
2.979PheThr: 2.979 ± 0.804
1.986PheVal: 1.986 ± 0.081
0.0PheTrp: 0.0 ± 0.0
1.986PheTyr: 1.986 ± 1.282
0.0PheXaa: 0.0 ± 0.0
Gly
1.986GlyAla: 1.986 ± 1.282
1.986GlyCys: 1.986 ± 1.445
3.972GlyAsp: 3.972 ± 0.163
0.993GlyGlu: 0.993 ± 0.641
7.944GlyPhe: 7.944 ± 2.402
5.958GlyGly: 5.958 ± 1.607
0.993GlyHis: 0.993 ± 0.722
2.979GlyIle: 2.979 ± 0.804
8.937GlyLys: 8.937 ± 0.316
4.965GlyLeu: 4.965 ± 0.479
1.986GlyMet: 1.986 ± 0.081
2.979GlyAsn: 2.979 ± 0.804
0.993GlyPro: 0.993 ± 0.641
2.979GlyGln: 2.979 ± 0.804
2.979GlyArg: 2.979 ± 0.804
3.972GlySer: 3.972 ± 1.526
0.993GlyThr: 0.993 ± 0.722
5.958GlyVal: 5.958 ± 1.12
0.0GlyTrp: 0.0 ± 0.0
5.958GlyTyr: 5.958 ± 0.244
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.993HisAsp: 0.993 ± 0.641
0.993HisGlu: 0.993 ± 0.641
2.979HisPhe: 2.979 ± 1.924
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.993HisLys: 0.993 ± 0.641
0.993HisLeu: 0.993 ± 0.641
1.986HisMet: 1.986 ± 0.081
0.0HisAsn: 0.0 ± 0.0
2.979HisPro: 2.979 ± 0.804
0.993HisGln: 0.993 ± 0.722
3.972HisArg: 3.972 ± 0.163
0.0HisSer: 0.0 ± 0.0
1.986HisThr: 1.986 ± 0.081
4.965HisVal: 4.965 ± 0.479
0.0HisTrp: 0.0 ± 0.0
0.993HisTyr: 0.993 ± 0.722
0.0HisXaa: 0.0 ± 0.0
Ile
6.951IleAla: 6.951 ± 0.397
1.986IleCys: 1.986 ± 1.282
7.944IleAsp: 7.944 ± 3.766
0.993IleGlu: 0.993 ± 0.722
0.993IlePhe: 0.993 ± 0.722
1.986IleGly: 1.986 ± 0.081
0.0IleHis: 0.0 ± 0.0
1.986IleIle: 1.986 ± 1.282
3.972IleLys: 3.972 ± 1.201
6.951IleLeu: 6.951 ± 0.966
1.986IleMet: 1.986 ± 0.081
1.986IleAsn: 1.986 ± 1.282
6.951IlePro: 6.951 ± 0.966
0.993IleGln: 0.993 ± 0.641
5.958IleArg: 5.958 ± 1.12
2.979IleSer: 2.979 ± 1.924
1.986IleThr: 1.986 ± 0.081
3.972IleVal: 3.972 ± 1.526
1.986IleTrp: 1.986 ± 1.282
2.979IleTyr: 2.979 ± 0.804
0.0IleXaa: 0.0 ± 0.0
Lys
0.993LysAla: 0.993 ± 0.722
0.993LysCys: 0.993 ± 0.722
2.979LysAsp: 2.979 ± 0.804
0.993LysGlu: 0.993 ± 0.641
0.0LysPhe: 0.0 ± 0.0
5.958LysGly: 5.958 ± 1.12
0.0LysHis: 0.0 ± 0.0
5.958LysIle: 5.958 ± 2.484
0.993LysLys: 0.993 ± 0.722
3.972LysLeu: 3.972 ± 1.201
0.0LysMet: 0.0 ± 0.0
3.972LysAsn: 3.972 ± 1.526
1.986LysPro: 1.986 ± 0.081
0.993LysGln: 0.993 ± 0.641
3.972LysArg: 3.972 ± 1.201
8.937LysSer: 8.937 ± 1.68
5.958LysThr: 5.958 ± 0.244
0.993LysVal: 0.993 ± 0.641
0.0LysTrp: 0.0 ± 0.0
3.972LysTyr: 3.972 ± 1.201
0.0LysXaa: 0.0 ± 0.0
Leu
11.917LeuAla: 11.917 ± 0.488
0.993LeuCys: 0.993 ± 0.641
0.993LeuAsp: 0.993 ± 0.641
3.972LeuGlu: 3.972 ± 1.201
0.993LeuPhe: 0.993 ± 0.641
6.951LeuGly: 6.951 ± 0.397
7.944LeuHis: 7.944 ± 0.325
6.951LeuIle: 6.951 ± 3.125
4.965LeuLys: 4.965 ± 2.249
6.951LeuLeu: 6.951 ± 2.33
0.993LeuMet: 0.993 ± 0.722
3.972LeuAsn: 3.972 ± 1.201
9.93LeuPro: 9.93 ± 1.77
0.993LeuGln: 0.993 ± 0.722
3.972LeuArg: 3.972 ± 1.526
1.986LeuSer: 1.986 ± 1.445
3.972LeuThr: 3.972 ± 0.163
1.986LeuVal: 1.986 ± 1.282
0.993LeuTrp: 0.993 ± 0.641
5.958LeuTyr: 5.958 ± 2.971
0.0LeuXaa: 0.0 ± 0.0
Met
0.993MetAla: 0.993 ± 0.722
0.0MetCys: 0.0 ± 0.0
0.993MetAsp: 0.993 ± 0.641
0.0MetGlu: 0.0 ± 0.0
0.993MetPhe: 0.993 ± 0.722
1.986MetGly: 1.986 ± 0.081
0.0MetHis: 0.0 ± 0.0
1.986MetIle: 1.986 ± 1.282
0.0MetLys: 0.0 ± 0.0
1.986MetLeu: 1.986 ± 0.081
0.993MetMet: 0.993 ± 0.722
0.0MetAsn: 0.0 ± 0.0
0.993MetPro: 0.993 ± 0.722
0.0MetGln: 0.0 ± 0.0
0.993MetArg: 0.993 ± 0.641
4.965MetSer: 4.965 ± 2.249
1.986MetThr: 1.986 ± 0.081
0.993MetVal: 0.993 ± 0.641
0.993MetTrp: 0.993 ± 0.641
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.958AsnAla: 5.958 ± 2.971
0.0AsnCys: 0.0 ± 0.0
0.993AsnAsp: 0.993 ± 0.722
1.986AsnGlu: 1.986 ± 1.445
0.0AsnPhe: 0.0 ± 0.0
2.979AsnGly: 2.979 ± 0.804
0.993AsnHis: 0.993 ± 0.641
2.979AsnIle: 2.979 ± 0.56
1.986AsnLys: 1.986 ± 1.282
3.972AsnLeu: 3.972 ± 1.201
0.993AsnMet: 0.993 ± 0.482
1.986AsnAsn: 1.986 ± 1.445
2.979AsnPro: 2.979 ± 1.924
1.986AsnGln: 1.986 ± 0.081
1.986AsnArg: 1.986 ± 0.081
0.993AsnSer: 0.993 ± 0.722
3.972AsnThr: 3.972 ± 1.526
1.986AsnVal: 1.986 ± 0.081
0.0AsnTrp: 0.0 ± 0.0
1.986AsnTyr: 1.986 ± 0.081
0.0AsnXaa: 0.0 ± 0.0
Pro
4.965ProAla: 4.965 ± 2.249
0.0ProCys: 0.0 ± 0.0
0.993ProAsp: 0.993 ± 0.641
0.993ProGlu: 0.993 ± 0.641
0.993ProPhe: 0.993 ± 0.641
4.965ProGly: 4.965 ± 0.479
0.993ProHis: 0.993 ± 0.641
4.965ProIle: 4.965 ± 0.479
2.979ProLys: 2.979 ± 0.804
7.944ProLeu: 7.944 ± 1.039
0.0ProMet: 0.0 ± 0.0
0.993ProAsn: 0.993 ± 0.722
1.986ProPro: 1.986 ± 0.081
0.993ProGln: 0.993 ± 0.641
2.979ProArg: 2.979 ± 0.56
10.924ProSer: 10.924 ± 0.235
1.986ProThr: 1.986 ± 0.081
5.958ProVal: 5.958 ± 2.971
0.993ProTrp: 0.993 ± 0.641
2.979ProTyr: 2.979 ± 0.804
0.0ProXaa: 0.0 ± 0.0
Gln
2.979GlnAla: 2.979 ± 2.167
0.993GlnCys: 0.993 ± 0.722
3.972GlnAsp: 3.972 ± 0.163
0.993GlnGlu: 0.993 ± 0.722
0.993GlnPhe: 0.993 ± 0.722
2.979GlnGly: 2.979 ± 0.804
0.0GlnHis: 0.0 ± 0.0
3.972GlnIle: 3.972 ± 1.526
1.986GlnLys: 1.986 ± 0.081
0.993GlnLeu: 0.993 ± 0.641
0.993GlnMet: 0.993 ± 0.641
0.0GlnAsn: 0.0 ± 0.0
0.993GlnPro: 0.993 ± 0.641
2.979GlnGln: 2.979 ± 0.804
3.972GlnArg: 3.972 ± 0.163
0.993GlnSer: 0.993 ± 0.641
0.993GlnThr: 0.993 ± 0.722
2.979GlnVal: 2.979 ± 0.804
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.972ArgAla: 3.972 ± 0.163
0.0ArgCys: 0.0 ± 0.0
4.965ArgAsp: 4.965 ± 1.842
3.972ArgGlu: 3.972 ± 1.201
2.979ArgPhe: 2.979 ± 0.56
1.986ArgGly: 1.986 ± 0.081
2.979ArgHis: 2.979 ± 0.56
2.979ArgIle: 2.979 ± 0.804
1.986ArgLys: 1.986 ± 1.282
3.972ArgLeu: 3.972 ± 2.89
2.979ArgMet: 2.979 ± 0.56
2.979ArgAsn: 2.979 ± 0.804
1.986ArgPro: 1.986 ± 1.282
1.986ArgGln: 1.986 ± 0.081
0.993ArgArg: 0.993 ± 0.641
3.972ArgSer: 3.972 ± 1.201
6.951ArgThr: 6.951 ± 1.761
0.0ArgVal: 0.0 ± 0.0
1.986ArgTrp: 1.986 ± 0.081
1.986ArgTyr: 1.986 ± 1.445
0.0ArgXaa: 0.0 ± 0.0
Ser
5.958SerAla: 5.958 ± 2.971
1.986SerCys: 1.986 ± 0.081
1.986SerAsp: 1.986 ± 1.445
2.979SerGlu: 2.979 ± 0.56
4.965SerPhe: 4.965 ± 2.249
6.951SerGly: 6.951 ± 2.33
2.979SerHis: 2.979 ± 0.56
5.958SerIle: 5.958 ± 0.244
2.979SerLys: 2.979 ± 0.804
2.979SerLeu: 2.979 ± 2.167
0.0SerMet: 0.0 ± 0.0
6.951SerAsn: 6.951 ± 3.694
2.979SerPro: 2.979 ± 0.56
1.986SerGln: 1.986 ± 1.445
4.965SerArg: 4.965 ± 1.842
4.965SerSer: 4.965 ± 0.885
4.965SerThr: 4.965 ± 0.479
5.958SerVal: 5.958 ± 2.484
0.993SerTrp: 0.993 ± 0.722
4.965SerTyr: 4.965 ± 0.479
0.0SerXaa: 0.0 ± 0.0
Thr
3.972ThrAla: 3.972 ± 0.163
1.986ThrCys: 1.986 ± 1.282
2.979ThrAsp: 2.979 ± 0.56
1.986ThrGlu: 1.986 ± 0.081
1.986ThrPhe: 1.986 ± 1.282
3.972ThrGly: 3.972 ± 0.163
0.993ThrHis: 0.993 ± 0.641
7.944ThrIle: 7.944 ± 1.689
2.979ThrLys: 2.979 ± 0.804
5.958ThrLeu: 5.958 ± 1.607
0.993ThrMet: 0.993 ± 0.641
2.979ThrAsn: 2.979 ± 0.56
3.972ThrPro: 3.972 ± 1.201
0.0ThrGln: 0.0 ± 0.0
1.986ThrArg: 1.986 ± 1.282
4.965ThrSer: 4.965 ± 2.249
1.986ThrThr: 1.986 ± 1.282
0.993ThrVal: 0.993 ± 0.722
1.986ThrTrp: 1.986 ± 0.081
1.986ThrTyr: 1.986 ± 1.282
0.0ThrXaa: 0.0 ± 0.0
Val
0.993ValAla: 0.993 ± 0.722
0.993ValCys: 0.993 ± 0.641
3.972ValAsp: 3.972 ± 0.163
6.951ValGlu: 6.951 ± 0.397
1.986ValPhe: 1.986 ± 1.445
2.979ValGly: 2.979 ± 0.56
2.979ValHis: 2.979 ± 0.804
4.965ValIle: 4.965 ± 3.206
2.979ValLys: 2.979 ± 0.56
1.986ValLeu: 1.986 ± 0.081
0.993ValMet: 0.993 ± 0.722
0.993ValAsn: 0.993 ± 0.641
4.965ValPro: 4.965 ± 0.885
1.986ValGln: 1.986 ± 0.081
2.979ValArg: 2.979 ± 0.56
4.965ValSer: 4.965 ± 0.885
2.979ValThr: 2.979 ± 0.56
3.972ValVal: 3.972 ± 0.163
0.0ValTrp: 0.0 ± 0.0
1.986ValTyr: 1.986 ± 1.282
0.0ValXaa: 0.0 ± 0.0
Trp
0.993TrpAla: 0.993 ± 0.641
0.0TrpCys: 0.0 ± 0.0
0.993TrpAsp: 0.993 ± 0.722
0.0TrpGlu: 0.0 ± 0.0
0.993TrpPhe: 0.993 ± 0.641
1.986TrpGly: 1.986 ± 0.081
0.0TrpHis: 0.0 ± 0.0
0.993TrpIle: 0.993 ± 0.641
1.986TrpLys: 1.986 ± 1.282
0.993TrpLeu: 0.993 ± 0.641
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.986TrpGln: 1.986 ± 1.282
0.993TrpArg: 0.993 ± 0.722
2.979TrpSer: 2.979 ± 1.924
0.993TrpThr: 0.993 ± 0.641
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.965TyrAla: 4.965 ± 0.885
0.0TyrCys: 0.0 ± 0.0
1.986TyrAsp: 1.986 ± 0.081
1.986TyrGlu: 1.986 ± 1.282
4.965TyrPhe: 4.965 ± 0.479
1.986TyrGly: 1.986 ± 1.282
0.993TyrHis: 0.993 ± 0.641
0.993TyrIle: 0.993 ± 0.641
2.979TyrLys: 2.979 ± 0.56
8.937TyrLeu: 8.937 ± 2.411
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.979TyrPro: 2.979 ± 0.56
2.979TyrGln: 2.979 ± 0.804
0.993TyrArg: 0.993 ± 0.722
3.972TyrSer: 3.972 ± 2.89
2.979TyrThr: 2.979 ± 0.56
0.993TyrVal: 0.993 ± 0.641
0.0TyrTrp: 0.0 ± 0.0
0.993TyrTyr: 0.993 ± 0.722
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1008 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski