Amino acid dipepetide frequency for Apple chlorotic leaf spot virus (isolate plum P863) (ACLSV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.155AlaAla: 3.155 ± 0.41
0.789AlaCys: 0.789 ± 0.389
1.972AlaAsp: 1.972 ± 0.847
1.972AlaGlu: 1.972 ± 0.624
3.155AlaPhe: 3.155 ± 2.139
5.915AlaGly: 5.915 ± 1.179
1.183AlaHis: 1.183 ± 0.583
3.943AlaIle: 3.943 ± 0.631
7.098AlaLys: 7.098 ± 1.761
2.366AlaLeu: 2.366 ± 0.716
0.789AlaMet: 0.789 ± 0.499
1.972AlaAsn: 1.972 ± 0.753
0.789AlaPro: 0.789 ± 0.734
0.789AlaGln: 0.789 ± 1.136
3.549AlaArg: 3.549 ± 0.495
5.126AlaSer: 5.126 ± 2.245
2.366AlaThr: 2.366 ± 1.09
2.76AlaVal: 2.76 ± 1.697
0.0AlaTrp: 0.0 ± 0.0
1.577AlaTyr: 1.577 ± 0.777
0.0AlaXaa: 0.0 ± 0.0
Cys
0.789CysAla: 0.789 ± 0.389
0.394CysCys: 0.394 ± 0.194
0.789CysAsp: 0.789 ± 0.389
1.183CysGlu: 1.183 ± 0.687
1.183CysPhe: 1.183 ± 0.583
2.366CysGly: 2.366 ± 1.166
0.789CysHis: 0.789 ± 0.389
0.789CysIle: 0.789 ± 0.734
0.394CysLys: 0.394 ± 0.194
2.366CysLeu: 2.366 ± 1.166
0.789CysMet: 0.789 ± 0.389
0.0CysAsn: 0.0 ± 0.0
1.183CysPro: 1.183 ± 0.583
0.0CysGln: 0.0 ± 0.0
2.366CysArg: 2.366 ± 0.467
2.366CysSer: 2.366 ± 1.166
0.789CysThr: 0.789 ± 0.389
0.789CysVal: 0.789 ± 0.389
0.394CysTrp: 0.394 ± 0.194
0.789CysTyr: 0.789 ± 0.499
0.0CysXaa: 0.0 ± 0.0
Asp
2.76AspAla: 2.76 ± 0.408
0.789AspCys: 0.789 ± 0.389
5.915AspAsp: 5.915 ± 1.439
3.549AspGlu: 3.549 ± 1.749
4.732AspPhe: 4.732 ± 0.965
4.338AspGly: 4.338 ± 0.896
0.789AspHis: 0.789 ± 0.389
3.943AspIle: 3.943 ± 1.693
2.366AspLys: 2.366 ± 1.166
4.732AspLeu: 4.732 ± 1.104
0.789AspMet: 0.789 ± 0.389
3.549AspAsn: 3.549 ± 0.593
1.972AspPro: 1.972 ± 2.083
2.76AspGln: 2.76 ± 0.897
2.76AspArg: 2.76 ± 0.619
3.943AspSer: 3.943 ± 1.693
0.789AspThr: 0.789 ± 0.499
2.366AspVal: 2.366 ± 1.166
1.183AspTrp: 1.183 ± 0.583
1.577AspTyr: 1.577 ± 0.287
0.0AspXaa: 0.0 ± 0.0
Glu
4.732GluAla: 4.732 ± 1.816
1.577GluCys: 1.577 ± 0.777
3.155GluAsp: 3.155 ± 0.704
5.521GluGlu: 5.521 ± 2.721
5.915GluPhe: 5.915 ± 1.601
4.732GluGly: 4.732 ± 0.862
1.577GluHis: 1.577 ± 2.671
6.703GluIle: 6.703 ± 1.802
6.703GluLys: 6.703 ± 2.523
4.732GluLeu: 4.732 ± 0.965
0.789GluMet: 0.789 ± 0.389
3.155GluAsn: 3.155 ± 1.567
2.366GluPro: 2.366 ± 1.166
2.76GluGln: 2.76 ± 1.737
3.549GluArg: 3.549 ± 0.994
4.338GluSer: 4.338 ± 0.158
1.577GluThr: 1.577 ± 0.287
6.309GluVal: 6.309 ± 1.798
1.183GluTrp: 1.183 ± 0.583
0.394GluTyr: 0.394 ± 0.194
0.0GluXaa: 0.0 ± 0.0
Phe
5.521PheAla: 5.521 ± 2.025
1.972PheCys: 1.972 ± 0.972
3.943PheAsp: 3.943 ± 0.631
5.521PheGlu: 5.521 ± 2.686
1.183PhePhe: 1.183 ± 0.358
2.366PheGly: 2.366 ± 0.716
2.366PheHis: 2.366 ± 0.467
4.338PheIle: 4.338 ± 1.632
3.943PheLys: 3.943 ± 1.118
5.915PheLeu: 5.915 ± 1.601
2.366PheMet: 2.366 ± 1.118
3.155PheAsn: 3.155 ± 0.704
2.366PhePro: 2.366 ± 0.467
1.183PheGln: 1.183 ± 1.163
3.155PheArg: 3.155 ± 2.337
4.338PheSer: 4.338 ± 1.37
3.155PheThr: 3.155 ± 1.389
1.577PheVal: 1.577 ± 0.287
0.394PheTrp: 0.394 ± 0.194
0.789PheTyr: 0.789 ± 0.389
0.0PheXaa: 0.0 ± 0.0
Gly
2.76GlyAla: 2.76 ± 1.737
1.972GlyCys: 1.972 ± 0.972
3.549GlyAsp: 3.549 ± 0.593
2.76GlyGlu: 2.76 ± 1.36
3.943GlyPhe: 3.943 ± 1.693
1.972GlyGly: 1.972 ± 1.66
0.394GlyHis: 0.394 ± 0.668
3.943GlyIle: 3.943 ± 1.181
5.126GlyLys: 5.126 ± 0.297
5.126GlyLeu: 5.126 ± 1.282
1.183GlyMet: 1.183 ± 1.163
3.943GlyAsn: 3.943 ± 1.693
2.76GlyPro: 2.76 ± 0.619
1.577GlyGln: 1.577 ± 0.287
3.943GlyArg: 3.943 ± 0.671
7.492GlySer: 7.492 ± 3.264
1.972GlyThr: 1.972 ± 0.624
7.492GlyVal: 7.492 ± 2.031
1.972GlyTrp: 1.972 ± 0.335
1.577GlyTyr: 1.577 ± 0.777
0.0GlyXaa: 0.0 ± 0.0
His
0.789HisAla: 0.789 ± 0.389
0.0HisCys: 0.0 ± 0.0
1.183HisAsp: 1.183 ± 0.583
1.183HisGlu: 1.183 ± 0.358
1.577HisPhe: 1.577 ± 0.287
0.789HisGly: 0.789 ± 0.734
0.789HisHis: 0.789 ± 0.389
2.76HisIle: 2.76 ± 1.36
1.972HisLys: 1.972 ± 0.972
2.366HisLeu: 2.366 ± 0.467
0.789HisMet: 0.789 ± 0.389
1.183HisAsn: 1.183 ± 0.583
0.394HisPro: 0.394 ± 0.194
1.577HisGln: 1.577 ± 0.998
1.577HisArg: 1.577 ± 0.287
1.972HisSer: 1.972 ± 0.335
1.183HisThr: 1.183 ± 0.583
1.183HisVal: 1.183 ± 0.583
0.789HisTrp: 0.789 ± 1.335
0.394HisTyr: 0.394 ± 0.194
0.0HisXaa: 0.0 ± 0.0
Ile
2.76IleAla: 2.76 ± 1.697
1.972IleCys: 1.972 ± 0.972
3.549IleAsp: 3.549 ± 0.593
3.943IleGlu: 3.943 ± 1.943
2.366IlePhe: 2.366 ± 0.853
1.972IleGly: 1.972 ± 0.972
2.76IleHis: 2.76 ± 0.632
1.577IleIle: 1.577 ± 0.777
8.281IleLys: 8.281 ± 1.834
5.521IleLeu: 5.521 ± 2.175
2.76IleMet: 2.76 ± 1.158
1.972IleAsn: 1.972 ± 0.624
3.943IlePro: 3.943 ± 2.496
3.549IleGln: 3.549 ± 0.495
1.577IleArg: 1.577 ± 0.287
5.915IleSer: 5.915 ± 3.337
0.789IleThr: 0.789 ± 0.734
1.577IleVal: 1.577 ± 0.777
0.789IleTrp: 0.789 ± 0.389
3.155IleTyr: 3.155 ± 0.81
0.0IleXaa: 0.0 ± 0.0
Lys
5.126LysAla: 5.126 ± 1.804
1.577LysCys: 1.577 ± 0.777
3.549LysAsp: 3.549 ± 0.994
4.732LysGlu: 4.732 ± 0.965
3.943LysPhe: 3.943 ± 0.97
7.886LysGly: 7.886 ± 0.54
0.789LysHis: 0.789 ± 0.389
3.943LysIle: 3.943 ± 1.181
7.886LysLys: 7.886 ± 1.724
7.098LysLeu: 7.098 ± 2.579
2.76LysMet: 2.76 ± 0.982
3.549LysAsn: 3.549 ± 0.593
3.155LysPro: 3.155 ± 0.81
1.183LysGln: 1.183 ± 1.163
3.943LysArg: 3.943 ± 0.671
7.492LysSer: 7.492 ± 0.838
3.155LysThr: 3.155 ± 1.389
6.309LysVal: 6.309 ± 0.781
0.789LysTrp: 0.789 ± 0.389
1.972LysTyr: 1.972 ± 1.409
0.0LysXaa: 0.0 ± 0.0
Leu
5.521LeuAla: 5.521 ± 1.944
2.366LeuCys: 2.366 ± 0.853
5.521LeuAsp: 5.521 ± 0.371
5.521LeuGlu: 5.521 ± 1.242
5.915LeuPhe: 5.915 ± 0.22
5.521LeuGly: 5.521 ± 0.815
0.789LeuHis: 0.789 ± 0.734
3.155LeuIle: 3.155 ± 1.13
6.309LeuLys: 6.309 ± 2.778
7.098LeuLeu: 7.098 ± 2.083
3.155LeuMet: 3.155 ± 0.435
3.155LeuAsn: 3.155 ± 1.214
3.155LeuPro: 3.155 ± 1.555
3.943LeuGln: 3.943 ± 1.248
6.309LeuArg: 6.309 ± 1.149
10.252LeuSer: 10.252 ± 1.293
3.549LeuThr: 3.549 ± 1.749
4.732LeuVal: 4.732 ± 1.104
0.394LeuTrp: 0.394 ± 0.194
1.183LeuTyr: 1.183 ± 0.583
0.0LeuXaa: 0.0 ± 0.0
Met
1.183MetAla: 1.183 ± 0.956
0.789MetCys: 0.789 ± 0.499
2.366MetAsp: 2.366 ± 1.166
1.972MetGlu: 1.972 ± 0.624
1.972MetPhe: 1.972 ± 1.568
0.394MetGly: 0.394 ± 0.668
0.394MetHis: 0.394 ± 0.194
2.76MetIle: 2.76 ± 0.619
3.549MetLys: 3.549 ± 1.749
1.183MetLeu: 1.183 ± 0.358
1.183MetMet: 1.183 ± 0.358
1.972MetAsn: 1.972 ± 1.409
2.366MetPro: 2.366 ± 0.49
0.0MetGln: 0.0 ± 0.0
1.183MetArg: 1.183 ± 0.583
1.183MetSer: 1.183 ± 0.583
1.183MetThr: 1.183 ± 0.687
2.76MetVal: 2.76 ± 1.36
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.183AsnAla: 1.183 ± 1.163
1.183AsnCys: 1.183 ± 0.583
1.972AsnAsp: 1.972 ± 0.335
2.366AsnGlu: 2.366 ± 1.09
3.155AsnPhe: 3.155 ± 1.997
3.549AsnGly: 3.549 ± 0.495
1.972AsnHis: 1.972 ± 0.972
3.155AsnIle: 3.155 ± 1.214
3.943AsnLys: 3.943 ± 2.693
4.732AsnLeu: 4.732 ± 2.867
1.972AsnMet: 1.972 ± 1.568
0.789AsnAsn: 0.789 ± 0.389
0.394AsnPro: 0.394 ± 0.668
1.183AsnGln: 1.183 ± 0.358
3.943AsnArg: 3.943 ± 1.248
2.366AsnSer: 2.366 ± 0.467
0.789AsnThr: 0.789 ± 0.389
2.366AsnVal: 2.366 ± 0.467
0.394AsnTrp: 0.394 ± 0.194
3.549AsnTyr: 3.549 ± 0.593
0.0AsnXaa: 0.0 ± 0.0
Pro
0.789ProAla: 0.789 ± 0.389
1.183ProCys: 1.183 ± 0.583
1.972ProAsp: 1.972 ± 0.972
4.732ProGlu: 4.732 ± 2.351
1.577ProPhe: 1.577 ± 0.287
2.366ProGly: 2.366 ± 2.326
1.183ProHis: 1.183 ± 0.583
1.972ProIle: 1.972 ± 0.847
2.76ProLys: 2.76 ± 0.632
5.521ProLeu: 5.521 ± 1.329
1.183ProMet: 1.183 ± 0.583
1.972ProAsn: 1.972 ± 1.283
0.789ProPro: 0.789 ± 0.389
0.789ProGln: 0.789 ± 0.389
1.577ProArg: 1.577 ± 0.287
1.577ProSer: 1.577 ± 1.83
1.183ProThr: 1.183 ± 0.358
1.972ProVal: 1.972 ± 0.847
0.394ProTrp: 0.394 ± 0.194
1.183ProTyr: 1.183 ± 0.583
0.0ProXaa: 0.0 ± 0.0
Gln
2.76GlnAla: 2.76 ± 2.159
0.394GlnCys: 0.394 ± 0.194
1.577GlnAsp: 1.577 ± 0.998
1.972GlnGlu: 1.972 ± 0.972
1.183GlnPhe: 1.183 ± 0.358
2.366GlnGly: 2.366 ± 1.09
0.394GlnHis: 0.394 ± 0.194
2.366GlnIle: 2.366 ± 0.49
1.577GlnLys: 1.577 ± 0.784
2.76GlnLeu: 2.76 ± 0.408
0.0GlnMet: 0.0 ± 0.0
1.972GlnAsn: 1.972 ± 1.66
0.789GlnPro: 0.789 ± 0.499
1.183GlnGln: 1.183 ± 0.956
1.972GlnArg: 1.972 ± 0.335
2.366GlnSer: 2.366 ± 0.49
2.76GlnThr: 2.76 ± 1.737
3.155GlnVal: 3.155 ± 0.41
0.0GlnTrp: 0.0 ± 0.0
0.394GlnTyr: 0.394 ± 0.194
0.0GlnXaa: 0.0 ± 0.0
Arg
1.577ArgAla: 1.577 ± 0.998
0.394ArgCys: 0.394 ± 0.194
1.183ArgAsp: 1.183 ± 0.583
7.492ArgGlu: 7.492 ± 1.251
3.943ArgPhe: 3.943 ± 1.181
4.732ArgGly: 4.732 ± 1.432
2.366ArgHis: 2.366 ± 1.166
2.76ArgIle: 2.76 ± 0.619
2.366ArgLys: 2.366 ± 3.164
8.281ArgLeu: 8.281 ± 1.834
1.577ArgMet: 1.577 ± 0.777
2.366ArgAsn: 2.366 ± 0.49
1.183ArgPro: 1.183 ± 0.687
1.972ArgGln: 1.972 ± 0.624
5.126ArgArg: 5.126 ± 0.297
5.126ArgSer: 5.126 ± 1.094
1.577ArgThr: 1.577 ± 0.777
2.366ArgVal: 2.366 ± 0.716
0.394ArgTrp: 0.394 ± 0.668
1.972ArgTyr: 1.972 ± 0.972
0.0ArgXaa: 0.0 ± 0.0
Ser
3.155SerAla: 3.155 ± 0.81
0.394SerCys: 0.394 ± 0.194
6.309SerAsp: 6.309 ± 0.869
7.492SerGlu: 7.492 ± 1.607
4.338SerPhe: 4.338 ± 1.556
5.521SerGly: 5.521 ± 4.318
2.366SerHis: 2.366 ± 1.166
5.126SerIle: 5.126 ± 2.245
5.915SerLys: 5.915 ± 0.674
5.521SerLeu: 5.521 ± 1.329
1.972SerMet: 1.972 ± 0.753
4.732SerAsn: 4.732 ± 0.862
2.76SerPro: 2.76 ± 1.343
4.338SerGln: 4.338 ± 0.789
3.943SerArg: 3.943 ± 0.671
9.858SerSer: 9.858 ± 2.979
3.549SerThr: 3.549 ± 1.311
5.915SerVal: 5.915 ± 1.601
0.789SerTrp: 0.789 ± 0.499
4.732SerTyr: 4.732 ± 0.965
0.0SerXaa: 0.0 ± 0.0
Thr
1.577ThrAla: 1.577 ± 0.287
0.789ThrCys: 0.789 ± 0.389
2.366ThrAsp: 2.366 ± 1.09
1.972ThrGlu: 1.972 ± 1.409
4.338ThrPhe: 4.338 ± 0.792
2.366ThrGly: 2.366 ± 0.49
0.789ThrHis: 0.789 ± 0.389
1.577ThrIle: 1.577 ± 0.777
1.972ThrLys: 1.972 ± 0.972
3.549ThrLeu: 3.549 ± 0.495
1.183ThrMet: 1.183 ± 0.956
1.972ThrAsn: 1.972 ± 1.568
1.183ThrPro: 1.183 ± 0.583
0.789ThrGln: 0.789 ± 0.499
1.972ThrArg: 1.972 ± 0.972
3.549ThrSer: 3.549 ± 1.403
1.577ThrThr: 1.577 ± 1.468
1.183ThrVal: 1.183 ± 0.358
0.0ThrTrp: 0.0 ± 0.0
0.394ThrTyr: 0.394 ± 0.194
0.0ThrXaa: 0.0 ± 0.0
Val
4.338ValAla: 4.338 ± 1.37
1.183ValCys: 1.183 ± 0.687
2.366ValAsp: 2.366 ± 1.09
5.126ValGlu: 5.126 ± 1.145
2.76ValPhe: 2.76 ± 0.408
3.155ValGly: 3.155 ± 0.704
1.972ValHis: 1.972 ± 0.847
4.338ValIle: 4.338 ± 0.792
5.521ValLys: 5.521 ± 1.106
5.126ValLeu: 5.126 ± 0.88
1.577ValMet: 1.577 ± 0.998
2.366ValAsn: 2.366 ± 0.853
2.366ValPro: 2.366 ± 0.716
1.183ValGln: 1.183 ± 0.358
3.549ValArg: 3.549 ± 0.593
4.338ValSer: 4.338 ± 1.769
1.972ValThr: 1.972 ± 0.335
1.577ValVal: 1.577 ± 1.468
0.394ValTrp: 0.394 ± 0.194
2.76ValTyr: 2.76 ± 0.632
0.0ValXaa: 0.0 ± 0.0
Trp
0.394TrpAla: 0.394 ± 0.194
0.789TrpCys: 0.789 ± 0.499
0.394TrpAsp: 0.394 ± 0.194
0.789TrpGlu: 0.789 ± 0.499
0.789TrpPhe: 0.789 ± 0.389
1.577TrpGly: 1.577 ± 0.287
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.789TrpLys: 0.789 ± 0.499
1.183TrpLeu: 1.183 ± 0.583
0.0TrpMet: 0.0 ± 0.0
0.394TrpAsn: 0.394 ± 0.668
0.394TrpPro: 0.394 ± 0.194
0.0TrpGln: 0.0 ± 0.0
1.183TrpArg: 1.183 ± 0.583
1.577TrpSer: 1.577 ± 0.777
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.394TrpTyr: 0.394 ± 0.194
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.394TyrAla: 0.394 ± 0.194
0.0TyrCys: 0.0 ± 0.0
1.972TyrAsp: 1.972 ± 0.335
1.972TyrGlu: 1.972 ± 0.972
1.577TyrPhe: 1.577 ± 0.777
1.577TyrGly: 1.577 ± 0.777
0.789TyrHis: 0.789 ± 0.389
1.577TyrIle: 1.577 ± 0.287
2.366TyrLys: 2.366 ± 0.853
2.76TyrLeu: 2.76 ± 0.632
1.183TyrMet: 1.183 ± 0.583
0.789TyrAsn: 0.789 ± 0.734
2.366TyrPro: 2.366 ± 0.49
1.183TyrGln: 1.183 ± 0.583
1.577TyrArg: 1.577 ± 0.777
3.549TyrSer: 3.549 ± 0.994
1.183TyrThr: 1.183 ± 0.583
1.577TyrVal: 1.577 ± 0.998
0.394TyrTrp: 0.394 ± 0.194
0.394TyrTyr: 0.394 ± 0.194
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2537 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski