Amino acid dipepetide frequency for Fonsecaea pedrosoi CBS 271.37

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.021AlaAla: 9.021 ± 0.05	1.12AlaCys: 1.12 ± 0.014	4.335AlaAsp: 4.335 ± 0.027	5.17AlaGlu: 5.17 ± 0.038	3.218AlaPhe: 3.218 ± 0.024	5.963AlaGly: 5.963 ± 0.036	1.826AlaHis: 1.826 ± 0.019	4.289AlaIle: 4.289 ± 0.03	3.969AlaLys: 3.969 ± 0.029	7.827AlaLeu: 7.827 ± 0.04	1.953AlaMet: 1.953 ± 0.018	2.929AlaAsn: 2.929 ± 0.021	4.486AlaPro: 4.486 ± 0.034	3.569AlaGln: 3.569 ± 0.027	5.125AlaArg: 5.125 ± 0.032	7.064AlaSer: 7.064 ± 0.04	5.441AlaThr: 5.441 ± 0.03	5.596AlaVal: 5.596 ± 0.036	1.186AlaTrp: 1.186 ± 0.014	2.203AlaTyr: 2.203 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.998CysAla: 0.998 ± 0.014	0.232CysCys: 0.232 ± 0.007	0.685CysAsp: 0.685 ± 0.011	0.584CysGlu: 0.584 ± 0.01	0.565CysPhe: 0.565 ± 0.009	0.915CysGly: 0.915 ± 0.014	0.342CysHis: 0.342 ± 0.008	0.706CysIle: 0.706 ± 0.011	0.494CysLys: 0.494 ± 0.009	1.326CysLeu: 1.326 ± 0.016	0.268CysMet: 0.268 ± 0.007	0.406CysAsn: 0.406 ± 0.009	0.669CysPro: 0.669 ± 0.012	0.452CysGln: 0.452 ± 0.01	0.78CysArg: 0.78 ± 0.014	0.872CysSer: 0.872 ± 0.013	0.696CysThr: 0.696 ± 0.011	0.835CysVal: 0.835 ± 0.012	0.208CysTrp: 0.208 ± 0.006	0.358CysTyr: 0.358 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.68AspAla: 4.68 ± 0.03	0.623AspCys: 0.623 ± 0.011	4.287AspAsp: 4.287 ± 0.043	4.436AspGlu: 4.436 ± 0.029	2.302AspPhe: 2.302 ± 0.022	4.041AspGly: 4.041 ± 0.032	1.343AspHis: 1.343 ± 0.015	2.992AspIle: 2.992 ± 0.02	2.399AspLys: 2.399 ± 0.025	5.249AspLeu: 5.249 ± 0.032	1.247AspMet: 1.247 ± 0.014	1.866AspAsn: 1.866 ± 0.017	3.445AspPro: 3.445 ± 0.027	2.037AspGln: 2.037 ± 0.021	3.162AspArg: 3.162 ± 0.03	3.96AspSer: 3.96 ± 0.028	3.012AspThr: 3.012 ± 0.024	3.826AspVal: 3.826 ± 0.027	0.901AspTrp: 0.901 ± 0.012	1.567AspTyr: 1.567 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.333GluAla: 5.333 ± 0.037	0.61GluCys: 0.61 ± 0.01	4.166GluAsp: 4.166 ± 0.029	5.159GluGlu: 5.159 ± 0.048	1.888GluPhe: 1.888 ± 0.019	3.641GluGly: 3.641 ± 0.026	1.462GluHis: 1.462 ± 0.019	3.097GluIle: 3.097 ± 0.022	3.56GluLys: 3.56 ± 0.027	5.096GluLeu: 5.096 ± 0.034	1.444GluMet: 1.444 ± 0.016	2.141GluAsn: 2.141 ± 0.02	2.713GluPro: 2.713 ± 0.027	2.548GluGln: 2.548 ± 0.026	3.929GluArg: 3.929 ± 0.031	4.147GluSer: 4.147 ± 0.034	3.453GluThr: 3.453 ± 0.024	3.627GluVal: 3.627 ± 0.024	0.876GluTrp: 0.876 ± 0.011	1.634GluTyr: 1.634 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.14PheAla: 3.14 ± 0.025	0.57PheCys: 0.57 ± 0.01	2.365PheAsp: 2.365 ± 0.022	2.179PheGlu: 2.179 ± 0.019	1.663PhePhe: 1.663 ± 0.018	2.939PheGly: 2.939 ± 0.026	0.908PheHis: 0.908 ± 0.014	1.752PheIle: 1.752 ± 0.02	1.43PheLys: 1.43 ± 0.015	3.533PheLeu: 3.533 ± 0.029	0.788PheMet: 0.788 ± 0.012	1.373PheAsn: 1.373 ± 0.016	2.003PhePro: 2.003 ± 0.018	1.405PheGln: 1.405 ± 0.015	2.004PheArg: 2.004 ± 0.02	2.916PheSer: 2.916 ± 0.022	2.113PheThr: 2.113 ± 0.018	2.516PheVal: 2.516 ± 0.02	0.674PheTrp: 0.674 ± 0.01	1.125PheTyr: 1.125 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.411GlyAla: 5.411 ± 0.037	0.882GlyCys: 0.882 ± 0.013	3.62GlyAsp: 3.62 ± 0.026	3.574GlyGlu: 3.574 ± 0.024	2.906GlyPhe: 2.906 ± 0.023	5.849GlyGly: 5.849 ± 0.054	1.727GlyHis: 1.727 ± 0.017	3.572GlyIle: 3.572 ± 0.028	3.309GlyLys: 3.309 ± 0.022	6.259GlyLeu: 6.259 ± 0.036	1.641GlyMet: 1.641 ± 0.02	2.413GlyAsn: 2.413 ± 0.025	3.439GlyPro: 3.439 ± 0.028	2.678GlyGln: 2.678 ± 0.021	4.22GlyArg: 4.22 ± 0.03	5.488GlySer: 5.488 ± 0.037	4.109GlyThr: 4.109 ± 0.025	4.581GlyVal: 4.581 ± 0.034	1.178GlyTrp: 1.178 ± 0.016	2.136GlyTyr: 2.136 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.964HisAla: 1.964 ± 0.02	0.332HisCys: 0.332 ± 0.008	1.43HisAsp: 1.43 ± 0.016	1.418HisGlu: 1.418 ± 0.014	0.946HisPhe: 0.946 ± 0.012	1.829HisGly: 1.829 ± 0.019	0.907HisHis: 0.907 ± 0.017	1.191HisIle: 1.191 ± 0.013	0.955HisLys: 0.955 ± 0.014	2.348HisLeu: 2.348 ± 0.022	0.503HisMet: 0.503 ± 0.009	0.828HisAsn: 0.828 ± 0.011	1.718HisPro: 1.718 ± 0.02	1.032HisGln: 1.032 ± 0.014	1.574HisArg: 1.574 ± 0.017	1.827HisSer: 1.827 ± 0.018	1.272HisThr: 1.272 ± 0.013	1.544HisVal: 1.544 ± 0.015	0.368HisTrp: 0.368 ± 0.007	0.693HisTyr: 0.693 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.219IleAla: 4.219 ± 0.032	0.786IleCys: 0.786 ± 0.012	2.853IleAsp: 2.853 ± 0.021	2.8IleGlu: 2.8 ± 0.024	1.976IlePhe: 1.976 ± 0.02	3.282IleGly: 3.282 ± 0.025	1.21IleHis: 1.21 ± 0.016	2.426IleIle: 2.426 ± 0.026	2.078IleLys: 2.078 ± 0.022	4.586IleLeu: 4.586 ± 0.032	0.986IleMet: 0.986 ± 0.015	1.721IleAsn: 1.721 ± 0.017	3.081IlePro: 3.081 ± 0.025	1.928IleGln: 1.928 ± 0.02	2.76IleArg: 2.76 ± 0.02	3.769IleSer: 3.769 ± 0.023	2.777IleThr: 2.777 ± 0.022	3.256IleVal: 3.256 ± 0.026	0.741IleTrp: 0.741 ± 0.011	1.427IleTyr: 1.427 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.103LysAla: 4.103 ± 0.028	0.505LysCys: 0.505 ± 0.01	2.778LysAsp: 2.778 ± 0.026	3.188LysGlu: 3.188 ± 0.027	1.435LysPhe: 1.435 ± 0.016	2.886LysGly: 2.886 ± 0.022	1.168LysHis: 1.168 ± 0.013	2.276LysIle: 2.276 ± 0.02	2.968LysLys: 2.968 ± 0.038	3.911LysLeu: 3.911 ± 0.025	1.022LysMet: 1.022 ± 0.013	1.573LysAsn: 1.573 ± 0.018	2.622LysPro: 2.622 ± 0.024	1.83LysGln: 1.83 ± 0.02	3.372LysArg: 3.372 ± 0.025	3.378LysSer: 3.378 ± 0.027	2.73LysThr: 2.73 ± 0.025	2.835LysVal: 2.835 ± 0.027	0.706LysTrp: 0.706 ± 0.01	1.391LysTyr: 1.391 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.936LeuAla: 7.936 ± 0.044	1.288LeuCys: 1.288 ± 0.017	5.278LeuAsp: 5.278 ± 0.036	5.555LeuGlu: 5.555 ± 0.036	3.351LeuPhe: 3.351 ± 0.025	6.045LeuGly: 6.045 ± 0.04	2.299LeuHis: 2.299 ± 0.021	3.934LeuIle: 3.934 ± 0.031	4.165LeuLys: 4.165 ± 0.03	8.409LeuLeu: 8.409 ± 0.051	1.828LeuMet: 1.828 ± 0.018	3.119LeuAsn: 3.119 ± 0.026	5.511LeuPro: 5.511 ± 0.031	3.882LeuGln: 3.882 ± 0.029	5.841LeuArg: 5.841 ± 0.038	7.222LeuSer: 7.222 ± 0.039	4.942LeuThr: 4.942 ± 0.031	5.603LeuVal: 5.603 ± 0.036	1.26LeuTrp: 1.26 ± 0.016	2.371LeuTyr: 2.371 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.249MetAla: 2.249 ± 0.02	0.258MetCys: 0.258 ± 0.006	1.193MetAsp: 1.193 ± 0.015	1.184MetGlu: 1.184 ± 0.016	0.772MetPhe: 0.772 ± 0.011	1.463MetGly: 1.463 ± 0.017	0.487MetHis: 0.487 ± 0.008	0.996MetIle: 0.996 ± 0.014	0.96MetLys: 0.96 ± 0.012	1.872MetLeu: 1.872 ± 0.019	0.528MetMet: 0.528 ± 0.01	0.788MetAsn: 0.788 ± 0.013	1.265MetPro: 1.265 ± 0.017	0.848MetGln: 0.848 ± 0.011	1.23MetArg: 1.23 ± 0.014	1.868MetSer: 1.868 ± 0.018	1.357MetThr: 1.357 ± 0.015	1.344MetVal: 1.344 ± 0.014	0.259MetTrp: 0.259 ± 0.007	0.536MetTyr: 0.536 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.117AsnAla: 3.117 ± 0.025	0.427AsnCys: 0.427 ± 0.008	1.903AsnAsp: 1.903 ± 0.02	1.918AsnGlu: 1.918 ± 0.018	1.339AsnPhe: 1.339 ± 0.015	2.891AsnGly: 2.891 ± 0.026	0.866AsnHis: 0.866 ± 0.012	1.927AsnIle: 1.927 ± 0.018	1.45AsnLys: 1.45 ± 0.016	3.22AsnLeu: 3.22 ± 0.026	0.779AsnMet: 0.779 ± 0.011	1.403AsnAsn: 1.403 ± 0.016	2.415AsnPro: 2.415 ± 0.023	1.296AsnGln: 1.296 ± 0.017	1.875AsnArg: 1.875 ± 0.019	2.534AsnSer: 2.534 ± 0.022	2.108AsnThr: 2.108 ± 0.019	2.364AsnVal: 2.364 ± 0.021	0.551AsnTrp: 0.551 ± 0.01	1.025AsnTyr: 1.025 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.027ProAla: 5.027 ± 0.043	0.518ProCys: 0.518 ± 0.01	3.32ProAsp: 3.32 ± 0.025	3.801ProGlu: 3.801 ± 0.028	2.059ProPhe: 2.059 ± 0.017	4.047ProGly: 4.047 ± 0.029	1.361ProHis: 1.361 ± 0.017	2.499ProIle: 2.499 ± 0.019	2.595ProLys: 2.595 ± 0.024	4.899ProLeu: 4.899 ± 0.033	1.065ProMet: 1.065 ± 0.014	2.193ProAsn: 2.193 ± 0.022	5.22ProPro: 5.22 ± 0.067	2.555ProGln: 2.555 ± 0.027	3.509ProArg: 3.509 ± 0.031	5.901ProSer: 5.901 ± 0.044	4.049ProThr: 4.049 ± 0.028	3.62ProVal: 3.62 ± 0.03	0.766ProTrp: 0.766 ± 0.013	1.511ProTyr: 1.511 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.555GlnAla: 3.555 ± 0.028	0.447GlnCys: 0.447 ± 0.009	2.168GlnAsp: 2.168 ± 0.019	2.439GlnGlu: 2.439 ± 0.025	1.304GlnPhe: 1.304 ± 0.016	2.535GlnGly: 2.535 ± 0.024	1.161GlnHis: 1.161 ± 0.016	1.974GlnIle: 1.974 ± 0.018	1.988GlnLys: 1.988 ± 0.018	3.446GlnLeu: 3.446 ± 0.027	0.91GlnMet: 0.91 ± 0.013	1.573GlnAsn: 1.573 ± 0.017	2.591GlnPro: 2.591 ± 0.026	2.384GlnGln: 2.384 ± 0.038	2.736GlnArg: 2.736 ± 0.026	3.235GlnSer: 3.235 ± 0.025	2.409GlnThr: 2.409 ± 0.023	2.283GlnVal: 2.283 ± 0.022	0.596GlnTrp: 0.596 ± 0.012	1.191GlnTyr: 1.191 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	4.828ArgAla: 4.828 ± 0.03	0.712ArgCys: 0.712 ± 0.011	3.528ArgAsp: 3.528 ± 0.03	3.85ArgGlu: 3.85 ± 0.03	2.124ArgPhe: 2.124 ± 0.021	3.756ArgGly: 3.756 ± 0.032	1.706ArgHis: 1.706 ± 0.017	2.869ArgIle: 2.869 ± 0.021	3.453ArgLys: 3.453 ± 0.027	5.599ArgLeu: 5.599 ± 0.031	1.278ArgMet: 1.278 ± 0.017	2.175ArgAsn: 2.175 ± 0.02	3.66ArgPro: 3.66 ± 0.031	2.753ArgGln: 2.753 ± 0.024	5.308ArgArg: 5.308 ± 0.042	4.756ArgSer: 4.756 ± 0.037	3.397ArgThr: 3.397 ± 0.024	3.381ArgVal: 3.381 ± 0.022	0.991ArgTrp: 0.991 ± 0.015	1.76ArgTyr: 1.76 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.537SerAla: 6.537 ± 0.038	0.851SerCys: 0.851 ± 0.014	4.13SerAsp: 4.13 ± 0.029	4.0SerGlu: 4.0 ± 0.032	2.927SerPhe: 2.927 ± 0.021	5.455SerGly: 5.455 ± 0.033	1.98SerHis: 1.98 ± 0.019	3.916SerIle: 3.916 ± 0.028	3.515SerLys: 3.515 ± 0.029	7.136SerLeu: 7.136 ± 0.039	1.676SerMet: 1.676 ± 0.016	2.803SerAsn: 2.803 ± 0.023	5.499SerPro: 5.499 ± 0.049	3.354SerGln: 3.354 ± 0.032	5.007SerArg: 5.007 ± 0.037	8.715SerSer: 8.715 ± 0.068	5.754SerThr: 5.754 ± 0.046	4.589SerVal: 4.589 ± 0.03	1.131SerTrp: 1.131 ± 0.015	2.002SerTyr: 2.002 ± 0.017	0.0SerXaa: 0.0 ± 0.0
Thr	5.335ThrAla: 5.335 ± 0.029	0.737ThrCys: 0.737 ± 0.011	2.916ThrAsp: 2.916 ± 0.025	3.064ThrGlu: 3.064 ± 0.027	2.317ThrPhe: 2.317 ± 0.02	4.268ThrGly: 4.268 ± 0.027	1.266ThrHis: 1.266 ± 0.014	3.087ThrIle: 3.087 ± 0.025	2.594ThrLys: 2.594 ± 0.022	5.258ThrLeu: 5.258 ± 0.033	1.239ThrMet: 1.239 ± 0.015	2.135ThrAsn: 2.135 ± 0.019	4.33ThrPro: 4.33 ± 0.033	2.155ThrGln: 2.155 ± 0.018	3.243ThrArg: 3.243 ± 0.024	5.578ThrSer: 5.578 ± 0.05	4.737ThrThr: 4.737 ± 0.058	3.828ThrVal: 3.828 ± 0.029	0.898ThrTrp: 0.898 ± 0.013	1.614ThrTyr: 1.614 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	5.487ValAla: 5.487 ± 0.034	0.86ValCys: 0.86 ± 0.012	3.902ValAsp: 3.902 ± 0.025	3.898ValGlu: 3.898 ± 0.028	2.509ValPhe: 2.509 ± 0.022	4.16ValGly: 4.16 ± 0.03	1.488ValHis: 1.488 ± 0.015	2.959ValIle: 2.959 ± 0.026	2.931ValLys: 2.931 ± 0.023	5.724ValLeu: 5.724 ± 0.04	1.316ValMet: 1.316 ± 0.016	2.29ValAsn: 2.29 ± 0.02	3.656ValPro: 3.656 ± 0.026	2.503ValGln: 2.503 ± 0.022	3.551ValArg: 3.551 ± 0.027	4.643ValSer: 4.643 ± 0.03	3.635ValThr: 3.635 ± 0.026	4.623ValVal: 4.623 ± 0.032	0.9ValTrp: 0.9 ± 0.014	1.754ValTyr: 1.754 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.137TrpAla: 1.137 ± 0.016	0.209TrpCys: 0.209 ± 0.006	0.886TrpAsp: 0.886 ± 0.013	0.802TrpGlu: 0.802 ± 0.012	0.549TrpPhe: 0.549 ± 0.011	0.906TrpGly: 0.906 ± 0.013	0.395TrpHis: 0.395 ± 0.009	0.819TrpIle: 0.819 ± 0.012	0.81TrpLys: 0.81 ± 0.012	1.402TrpLeu: 1.402 ± 0.015	0.369TrpMet: 0.369 ± 0.008	0.61TrpAsn: 0.61 ± 0.009	0.657TrpPro: 0.657 ± 0.01	0.593TrpGln: 0.593 ± 0.009	1.012TrpArg: 1.012 ± 0.013	1.11TrpSer: 1.11 ± 0.013	1.011TrpThr: 1.011 ± 0.012	0.885TrpVal: 0.885 ± 0.013	0.285TrpTrp: 0.285 ± 0.007	0.473TrpTyr: 0.473 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.213TyrAla: 2.213 ± 0.02	0.424TyrCys: 0.424 ± 0.01	1.632TyrAsp: 1.632 ± 0.018	1.506TyrGlu: 1.506 ± 0.016	1.247TyrPhe: 1.247 ± 0.016	2.122TyrGly: 2.122 ± 0.023	0.779TyrHis: 0.779 ± 0.013	1.38TyrIle: 1.38 ± 0.016	1.054TyrLys: 1.054 ± 0.016	2.74TyrLeu: 2.74 ± 0.026	0.619TyrMet: 0.619 ± 0.01	1.068TyrAsn: 1.068 ± 0.015	1.531TyrPro: 1.531 ± 0.017	1.123TyrGln: 1.123 ± 0.013	1.645TyrArg: 1.645 ± 0.019	1.992TyrSer: 1.992 ± 0.021	1.599TyrThr: 1.599 ± 0.019	1.65TyrVal: 1.65 ± 0.016	0.447TyrTrp: 0.447 ± 0.008	0.933TyrTyr: 0.933 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12525 proteins (6141607 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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