Amino acid dipepetide frequency for Deinococcus ficus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.28AlaAla: 18.28 ± 0.164	0.9AlaCys: 0.9 ± 0.029	6.242AlaAsp: 6.242 ± 0.078	6.515AlaGlu: 6.515 ± 0.088	4.23AlaPhe: 4.23 ± 0.067	12.231AlaGly: 12.231 ± 0.127	3.003AlaHis: 3.003 ± 0.058	3.216AlaIle: 3.216 ± 0.057	2.331AlaLys: 2.331 ± 0.064	16.933AlaLeu: 16.933 ± 0.171	2.45AlaMet: 2.45 ± 0.046	2.112AlaAsn: 2.112 ± 0.051	7.111AlaPro: 7.111 ± 0.103	6.058AlaGln: 6.058 ± 0.082	10.781AlaArg: 10.781 ± 0.113	5.331AlaSer: 5.331 ± 0.074	6.023AlaThr: 6.023 ± 0.081	9.222AlaVal: 9.222 ± 0.103	1.996AlaTrp: 1.996 ± 0.049	2.95AlaTyr: 2.95 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	0.723CysAla: 0.723 ± 0.025	0.058CysCys: 0.058 ± 0.007	0.313CysAsp: 0.313 ± 0.019	0.269CysGlu: 0.269 ± 0.016	0.159CysPhe: 0.159 ± 0.01	0.699CysGly: 0.699 ± 0.025	0.154CysHis: 0.154 ± 0.013	0.179CysIle: 0.179 ± 0.013	0.098CysLys: 0.098 ± 0.009	0.581CysLeu: 0.581 ± 0.021	0.093CysMet: 0.093 ± 0.009	0.136CysAsn: 0.136 ± 0.01	0.417CysPro: 0.417 ± 0.018	0.178CysGln: 0.178 ± 0.014	0.445CysArg: 0.445 ± 0.021	0.28CysSer: 0.28 ± 0.015	0.439CysThr: 0.439 ± 0.02	0.45CysVal: 0.45 ± 0.018	0.079CysTrp: 0.079 ± 0.008	0.119CysTyr: 0.119 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.353AspAla: 7.353 ± 0.073	0.242AspCys: 0.242 ± 0.015	2.654AspAsp: 2.654 ± 0.05	2.824AspGlu: 2.824 ± 0.057	1.734AspPhe: 1.734 ± 0.038	4.799AspGly: 4.799 ± 0.073	1.298AspHis: 1.298 ± 0.036	1.708AspIle: 1.708 ± 0.043	0.906AspLys: 0.906 ± 0.029	7.432AspLeu: 7.432 ± 0.092	0.895AspMet: 0.895 ± 0.028	0.834AspAsn: 0.834 ± 0.03	3.84AspPro: 3.84 ± 0.057	1.605AspGln: 1.605 ± 0.037	3.894AspArg: 3.894 ± 0.07	1.949AspSer: 1.949 ± 0.04	2.998AspThr: 2.998 ± 0.051	4.773AspVal: 4.773 ± 0.071	0.876AspTrp: 0.876 ± 0.029	1.066AspTyr: 1.066 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	7.188GluAla: 7.188 ± 0.092	0.261GluCys: 0.261 ± 0.015	2.666GluAsp: 2.666 ± 0.054	2.691GluGlu: 2.691 ± 0.059	1.638GluPhe: 1.638 ± 0.039	4.276GluGly: 4.276 ± 0.065	1.428GluHis: 1.428 ± 0.04	1.849GluIle: 1.849 ± 0.048	1.489GluLys: 1.489 ± 0.044	5.645GluLeu: 5.645 ± 0.074	0.957GluMet: 0.957 ± 0.032	1.16GluAsn: 1.16 ± 0.031	2.343GluPro: 2.343 ± 0.048	2.308GluGln: 2.308 ± 0.053	4.717GluArg: 4.717 ± 0.073	1.898GluSer: 1.898 ± 0.035	2.66GluThr: 2.66 ± 0.052	4.391GluVal: 4.391 ± 0.076	0.736GluTrp: 0.736 ± 0.027	1.26GluTyr: 1.26 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.273PheAla: 3.273 ± 0.052	0.181PheCys: 0.181 ± 0.011	1.845PheAsp: 1.845 ± 0.042	1.635PheGlu: 1.635 ± 0.031	0.902PhePhe: 0.902 ± 0.035	2.961PheGly: 2.961 ± 0.05	0.665PheHis: 0.665 ± 0.025	1.139PheIle: 1.139 ± 0.032	0.744PheLys: 0.744 ± 0.03	3.264PheLeu: 3.264 ± 0.064	0.657PheMet: 0.657 ± 0.02	0.825PheAsn: 0.825 ± 0.03	1.707PhePro: 1.707 ± 0.04	1.138PheGln: 1.138 ± 0.033	2.073PheArg: 2.073 ± 0.048	1.607PheSer: 1.607 ± 0.038	2.585PheThr: 2.585 ± 0.051	2.271PheVal: 2.271 ± 0.044	0.435PheTrp: 0.435 ± 0.019	0.7PheTyr: 0.7 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	10.092GlyAla: 10.092 ± 0.117	0.565GlyCys: 0.565 ± 0.021	4.346GlyAsp: 4.346 ± 0.063	5.096GlyGlu: 5.096 ± 0.073	2.896GlyPhe: 2.896 ± 0.055	8.342GlyGly: 8.342 ± 0.104	2.099GlyHis: 2.099 ± 0.047	3.037GlyIle: 3.037 ± 0.055	2.577GlyLys: 2.577 ± 0.048	10.212GlyLeu: 10.212 ± 0.101	2.035GlyMet: 2.035 ± 0.045	2.124GlyAsn: 2.124 ± 0.048	4.215GlyPro: 4.215 ± 0.064	4.045GlyGln: 4.045 ± 0.06	6.726GlyArg: 6.726 ± 0.088	4.486GlySer: 4.486 ± 0.065	6.066GlyThr: 6.066 ± 0.1	7.946GlyVal: 7.946 ± 0.092	1.438GlyTrp: 1.438 ± 0.037	2.263GlyTyr: 2.263 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	3.362HisAla: 3.362 ± 0.073	0.159HisCys: 0.159 ± 0.012	1.254HisAsp: 1.254 ± 0.037	1.197HisGlu: 1.197 ± 0.036	0.76HisPhe: 0.76 ± 0.023	2.162HisGly: 2.162 ± 0.043	0.737HisHis: 0.737 ± 0.029	0.606HisIle: 0.606 ± 0.027	0.341HisLys: 0.341 ± 0.019	3.16HisLeu: 3.16 ± 0.056	0.375HisMet: 0.375 ± 0.017	0.388HisAsn: 0.388 ± 0.02	1.934HisPro: 1.934 ± 0.039	0.68HisGln: 0.68 ± 0.026	1.603HisArg: 1.603 ± 0.038	0.911HisSer: 0.911 ± 0.026	1.37HisThr: 1.37 ± 0.036	1.79HisVal: 1.79 ± 0.041	0.367HisTrp: 0.367 ± 0.018	0.576HisTyr: 0.576 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	3.824IleAla: 3.824 ± 0.075	0.187IleCys: 0.187 ± 0.013	1.743IleAsp: 1.743 ± 0.04	1.887IleGlu: 1.887 ± 0.043	0.911IlePhe: 0.911 ± 0.03	3.144IleGly: 3.144 ± 0.064	0.781IleHis: 0.781 ± 0.029	1.184IleIle: 1.184 ± 0.037	0.839IleLys: 0.839 ± 0.031	3.272IleLeu: 3.272 ± 0.058	0.557IleMet: 0.557 ± 0.023	0.854IleAsn: 0.854 ± 0.029	1.958IlePro: 1.958 ± 0.041	1.256IleGln: 1.256 ± 0.035	2.417IleArg: 2.417 ± 0.045	1.703IleSer: 1.703 ± 0.047	2.446IleThr: 2.446 ± 0.049	2.715IleVal: 2.715 ± 0.05	0.314IleTrp: 0.314 ± 0.018	0.688IleTyr: 0.688 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.077LysAla: 3.077 ± 0.065	0.108LysCys: 0.108 ± 0.01	1.338LysAsp: 1.338 ± 0.036	1.07LysGlu: 1.07 ± 0.037	0.716LysPhe: 0.716 ± 0.028	1.877LysGly: 1.877 ± 0.05	0.487LysHis: 0.487 ± 0.019	0.926LysIle: 0.926 ± 0.031	0.966LysLys: 0.966 ± 0.037	2.477LysLeu: 2.477 ± 0.052	0.547LysMet: 0.547 ± 0.022	0.715LysAsn: 0.715 ± 0.031	1.31LysPro: 1.31 ± 0.039	0.738LysGln: 0.738 ± 0.026	1.54LysArg: 1.54 ± 0.038	1.006LysSer: 1.006 ± 0.033	1.505LysThr: 1.505 ± 0.044	2.022LysVal: 2.022 ± 0.052	0.267LysTrp: 0.267 ± 0.016	0.619LysTyr: 0.619 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	14.182LeuAla: 14.182 ± 0.145	0.718LeuCys: 0.718 ± 0.025	6.821LeuAsp: 6.821 ± 0.093	5.664LeuGlu: 5.664 ± 0.077	2.847LeuPhe: 2.847 ± 0.063	10.461LeuGly: 10.461 ± 0.116	3.101LeuHis: 3.101 ± 0.062	4.382LeuIle: 4.382 ± 0.07	3.187LeuLys: 3.187 ± 0.064	13.372LeuLeu: 13.372 ± 0.183	2.159LeuMet: 2.159 ± 0.046	3.492LeuAsn: 3.492 ± 0.05	7.669LeuPro: 7.669 ± 0.092	3.695LeuGln: 3.695 ± 0.068	8.652LeuArg: 8.652 ± 0.103	6.699LeuSer: 6.699 ± 0.089	8.816LeuThr: 8.816 ± 0.103	7.204LeuVal: 7.204 ± 0.089	1.256LeuTrp: 1.256 ± 0.039	2.348LeuTyr: 2.348 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	1.882MetAla: 1.882 ± 0.044	0.085MetCys: 0.085 ± 0.008	0.998MetAsp: 0.998 ± 0.03	0.805MetGlu: 0.805 ± 0.026	0.538MetPhe: 0.538 ± 0.02	1.452MetGly: 1.452 ± 0.038	0.409MetHis: 0.409 ± 0.018	0.824MetIle: 0.824 ± 0.027	0.701MetLys: 0.701 ± 0.025	2.105MetLeu: 2.105 ± 0.048	0.378MetMet: 0.378 ± 0.022	0.756MetAsn: 0.756 ± 0.026	1.203MetPro: 1.203 ± 0.033	0.796MetGln: 0.796 ± 0.025	1.417MetArg: 1.417 ± 0.031	1.114MetSer: 1.114 ± 0.033	2.09MetThr: 2.09 ± 0.045	1.204MetVal: 1.204 ± 0.032	0.185MetTrp: 0.185 ± 0.012	0.384MetTyr: 0.384 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.081AsnAla: 3.081 ± 0.056	0.135AsnCys: 0.135 ± 0.011	1.131AsnAsp: 1.131 ± 0.033	0.989AsnGlu: 0.989 ± 0.027	0.806AsnPhe: 0.806 ± 0.029	1.971AsnGly: 1.971 ± 0.05	0.477AsnHis: 0.477 ± 0.02	0.903AsnIle: 0.903 ± 0.029	0.498AsnLys: 0.498 ± 0.023	2.807AsnLeu: 2.807 ± 0.055	0.482AsnMet: 0.482 ± 0.021	0.622AsnAsn: 0.622 ± 0.03	1.776AsnPro: 1.776 ± 0.04	0.639AsnGln: 0.639 ± 0.026	1.459AsnArg: 1.459 ± 0.034	1.014AsnSer: 1.014 ± 0.03	1.447AsnThr: 1.447 ± 0.05	2.194AsnVal: 2.194 ± 0.048	0.347AsnTrp: 0.347 ± 0.016	0.616AsnTyr: 0.616 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	9.092ProAla: 9.092 ± 0.115	0.289ProCys: 0.289 ± 0.018	4.756ProAsp: 4.756 ± 0.067	4.142ProGlu: 4.142 ± 0.064	1.767ProPhe: 1.767 ± 0.037	6.278ProGly: 6.278 ± 0.072	1.498ProHis: 1.498 ± 0.045	1.45ProIle: 1.45 ± 0.036	1.146ProLys: 1.146 ± 0.033	6.261ProLeu: 6.261 ± 0.082	1.135ProMet: 1.135 ± 0.031	1.238ProAsn: 1.238 ± 0.035	3.259ProPro: 3.259 ± 0.073	2.13ProGln: 2.13 ± 0.035	3.563ProArg: 3.563 ± 0.05	2.527ProSer: 2.527 ± 0.049	3.356ProThr: 3.356 ± 0.055	4.993ProVal: 4.993 ± 0.074	0.776ProTrp: 0.776 ± 0.026	1.255ProTyr: 1.255 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	6.144GlnAla: 6.144 ± 0.084	0.149GlnCys: 0.149 ± 0.01	2.201GlnAsp: 2.201 ± 0.045	2.046GlnGlu: 2.046 ± 0.037	1.035GlnPhe: 1.035 ± 0.029	3.795GlnGly: 3.795 ± 0.063	0.799GlnHis: 0.799 ± 0.028	1.194GlnIle: 1.194 ± 0.035	0.93GlnLys: 0.93 ± 0.03	3.799GlnLeu: 3.799 ± 0.067	0.667GlnMet: 0.667 ± 0.024	0.882GlnAsn: 0.882 ± 0.026	2.355GlnPro: 2.355 ± 0.045	1.51GlnGln: 1.51 ± 0.039	2.579GlnArg: 2.579 ± 0.061	1.586GlnSer: 1.586 ± 0.041	2.126GlnThr: 2.126 ± 0.044	3.484GlnVal: 3.484 ± 0.067	0.455GlnTrp: 0.455 ± 0.02	0.787GlnTyr: 0.787 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	10.035ArgAla: 10.035 ± 0.113	0.403ArgCys: 0.403 ± 0.019	4.216ArgAsp: 4.216 ± 0.061	4.73ArgGlu: 4.73 ± 0.065	2.269ArgPhe: 2.269 ± 0.041	5.717ArgGly: 5.717 ± 0.078	1.877ArgHis: 1.877 ± 0.045	2.395ArgIle: 2.395 ± 0.047	1.502ArgLys: 1.502 ± 0.04	8.224ArgLeu: 8.224 ± 0.102	1.619ArgMet: 1.619 ± 0.033	1.563ArgAsn: 1.563 ± 0.036	4.473ArgPro: 4.473 ± 0.071	3.001ArgGln: 3.001 ± 0.058	5.842ArgArg: 5.842 ± 0.072	3.24ArgSer: 3.24 ± 0.06	4.576ArgThr: 4.576 ± 0.07	6.43ArgVal: 6.43 ± 0.084	1.072ArgTrp: 1.072 ± 0.036	1.778ArgTyr: 1.778 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	5.956SerAla: 5.956 ± 0.082	0.282SerCys: 0.282 ± 0.016	2.196SerAsp: 2.196 ± 0.045	2.029SerGlu: 2.029 ± 0.044	1.571SerPhe: 1.571 ± 0.038	5.392SerGly: 5.392 ± 0.078	0.895SerHis: 0.895 ± 0.028	1.47SerIle: 1.47 ± 0.038	1.008SerLys: 1.008 ± 0.032	5.104SerLeu: 5.104 ± 0.067	1.026SerMet: 1.026 ± 0.034	1.007SerAsn: 1.007 ± 0.035	2.934SerPro: 2.934 ± 0.048	1.322SerGln: 1.322 ± 0.036	3.225SerArg: 3.225 ± 0.054	2.4SerSer: 2.4 ± 0.066	2.743SerThr: 2.743 ± 0.052	4.077SerVal: 4.077 ± 0.06	0.627SerTrp: 0.627 ± 0.025	1.015SerTyr: 1.015 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	7.464ThrAla: 7.464 ± 0.098	0.414ThrCys: 0.414 ± 0.019	3.259ThrAsp: 3.259 ± 0.045	2.737ThrGlu: 2.737 ± 0.054	2.288ThrPhe: 2.288 ± 0.049	5.985ThrGly: 5.985 ± 0.085	1.462ThrHis: 1.462 ± 0.036	1.813ThrIle: 1.813 ± 0.05	0.997ThrLys: 0.997 ± 0.03	8.865ThrLeu: 8.865 ± 0.107	0.896ThrMet: 0.896 ± 0.031	1.268ThrAsn: 1.268 ± 0.037	5.528ThrPro: 5.528 ± 0.079	2.064ThrGln: 2.064 ± 0.051	4.627ThrArg: 4.627 ± 0.078	2.703ThrSer: 2.703 ± 0.055	3.795ThrThr: 3.795 ± 0.093	5.583ThrVal: 5.583 ± 0.097	0.833ThrTrp: 0.833 ± 0.028	1.616ThrTyr: 1.616 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	8.329ValAla: 8.329 ± 0.1	0.473ValCys: 0.473 ± 0.021	3.765ValAsp: 3.765 ± 0.065	3.585ValGlu: 3.585 ± 0.06	2.362ValPhe: 2.362 ± 0.047	5.826ValGly: 5.826 ± 0.077	1.652ValHis: 1.652 ± 0.044	3.486ValIle: 3.486 ± 0.055	2.292ValLys: 2.292 ± 0.053	9.026ValLeu: 9.026 ± 0.106	1.765ValMet: 1.765 ± 0.04	2.486ValAsn: 2.486 ± 0.054	4.842ValPro: 4.842 ± 0.068	3.829ValGln: 3.829 ± 0.057	6.2ValArg: 6.2 ± 0.088	4.096ValSer: 4.096 ± 0.065	6.622ValThr: 6.622 ± 0.09	5.925ValVal: 5.925 ± 0.075	1.07ValTrp: 1.07 ± 0.029	1.738ValTyr: 1.738 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.565TrpAla: 1.565 ± 0.042	0.098TrpCys: 0.098 ± 0.01	0.662TrpAsp: 0.662 ± 0.025	0.599TrpGlu: 0.599 ± 0.024	0.384TrpPhe: 0.384 ± 0.019	1.025TrpGly: 1.025 ± 0.031	0.358TrpHis: 0.358 ± 0.018	0.38TrpIle: 0.38 ± 0.019	0.366TrpLys: 0.366 ± 0.018	1.68TrpLeu: 1.68 ± 0.041	0.308TrpMet: 0.308 ± 0.018	0.431TrpAsn: 0.431 ± 0.02	0.773TrpPro: 0.773 ± 0.028	0.703TrpGln: 0.703 ± 0.027	1.113TrpArg: 1.113 ± 0.038	0.627TrpSer: 0.627 ± 0.026	1.078TrpThr: 1.078 ± 0.03	1.045TrpVal: 1.045 ± 0.032	0.256TrpTrp: 0.256 ± 0.014	0.268TrpTyr: 0.268 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.01TyrAla: 3.01 ± 0.053	0.163TyrCys: 0.163 ± 0.012	1.274TyrAsp: 1.274 ± 0.038	1.052TyrGlu: 1.052 ± 0.029	0.792TyrPhe: 0.792 ± 0.028	2.216TyrGly: 2.216 ± 0.038	0.551TyrHis: 0.551 ± 0.022	0.54TyrIle: 0.54 ± 0.02	0.393TyrLys: 0.393 ± 0.021	2.507TyrLeu: 2.507 ± 0.05	0.327TyrMet: 0.327 ± 0.017	0.501TyrAsn: 0.501 ± 0.022	1.265TyrPro: 1.265 ± 0.03	0.826TyrGln: 0.826 ± 0.027	2.09TyrArg: 2.09 ± 0.041	1.102TyrSer: 1.102 ± 0.033	1.455TyrThr: 1.455 ± 0.04	1.651TyrVal: 1.651 ± 0.038	0.332TyrTrp: 0.332 ± 0.017	0.59TyrTyr: 0.59 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3884 proteins (1209110 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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